#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O75558 uniprotkb:Q15833 intact:EBI-714135|uniprotkb:O75378|uniprotkb:O95148|uniprotkb:Q5TCL6|ensembl:ENSP00000356540|uniprotkb:E1P598 intact:EBI-4401015|uniprotkb:Q9BU65|uniprotkb:B4E175|uniprotkb:E7EQD5|ensembl:ENSP00000221283 psi-mi:stx11_human(display_long)|uniprotkb:STX11(gene name)|psi-mi:STX11(display_short) psi-mi:stxb2_human(display_long)|uniprotkb:STXBP2(gene name)|psi-mi:STXBP2(display_short)|uniprotkb:UNC18B(gene name synonym)|uniprotkb:Protein unc-18 homolog 2(gene name synonym)|uniprotkb:Protein unc-18 homolog B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Côte et al. (2009) imex:IM-29089|pubmed:19884660 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-27034912|imex:IM-29089-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028672|interpro:IPR042781|mint:O75558|ensembl:ENSG00000135604(gene)|ensembl:ENST00000367568(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0048278"(vesicle docking)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0061025"(membrane fusion)|refseq:NP_003755.2|refseq:XP_016866889.1|refseq:XP_011534516.1|refseq:XP_011534519.1|refseq:XP_011534520.1 refseq:NP_001120868.1|refseq:NP_008880.2|refseq:NP_001258963.1|ensembl:ENSG00000076944(gene)|ensembl:ENST00000221283(transcript)|go:"GO:0001909"(leukocyte mediated cytotoxicity)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030348"(syntaxin-3 binding)|go:"GO:0042581"(specific granule)|go:"GO:0042582"(azurophil granule)|go:"GO:0043304"(regulation of mast cell degranulation)|go:"GO:0043312"(neutrophil degranulation)|go:"GO:0044194"(cytolytic granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070820"(tertiary granule)|go:"GO:0098793"(presynapse)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|rcsb pdb:4CCA|reactome:R-HSA-114608|reactome:R-HSA-449836 - - - figure legend:Supp. Fig. 1|comment:"Splice mutant of STXBP2 - IVS14-1G>C [NM_006949.4:c.1247-1G>C/rs140148806] was still able to interact with STX11"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2021/07/15 2021/07/15 rogid:LckEg7WERVC628sZGjvi3qlYJ549606 rogid:KNJQ1UD62S+WDYG1zWW0NOjVmLc9606 rigid:o/eEmTZo1JthYsRVVPS/YZD5Okg false flag tag:n-n enhanced green fluorescent protein tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)