#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P59637 uniprotkb:P59637 intact:EBI-25487741|uniprotkb:Q7TA13|uniprotkb:Q7TFA8 intact:EBI-25487741|uniprotkb:Q7TA13|uniprotkb:Q7TFA8 psi-mi:vemp_sars(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name) psi-mi:vemp_sars(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name) psi-mi:"MI:0676"(tandem affinity purification) Alvarez et al. (2010) pubmed:20409569|imex:IM-28038 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25635717|imex:IM-28038-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|rcsb pdb:7NTJ|go:"GO:0000139"(Golgi membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044377|rcsb pdb:2MM4|rcsb pdb:5X29|rcsb pdb:5XER|rcsb pdb:5XES|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR043506|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683683|reactome:R-HSA-9683701|refseq:NP_828854.1 go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|rcsb pdb:7NTJ|go:"GO:0000139"(Golgi membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044377|rcsb pdb:2MM4|rcsb pdb:5X29|rcsb pdb:5XER|rcsb pdb:5XES|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR043506|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683683|reactome:R-HSA-9683701|refseq:NP_828854.1 - - - figure legend:Fig. 4a, Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/06/03 2020/06/17 rogid:RohltRPJbmvNaZQpQQDxwwUkjd0694009 rogid:RohltRPJbmvNaZQpQQDxwwUkjd0694009 rigid:bKaEeWxqmc+DK4SOFVxQedr9P5g false tandem tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P59637 uniprotkb:P59596 intact:EBI-25487741|uniprotkb:Q7TA13|uniprotkb:Q7TFA8 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 psi-mi:vemp_sars(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name) psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:"MI:0676"(tandem affinity purification) Alvarez et al. (2010) pubmed:20409569|imex:IM-28038 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25635717|imex:IM-28038-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|rcsb pdb:7NTJ|go:"GO:0000139"(Golgi membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044377|rcsb pdb:2MM4|rcsb pdb:5X29|rcsb pdb:5XER|rcsb pdb:5XES|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR043506|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683683|reactome:R-HSA-9683701|refseq:NP_828854.1 go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 - - - figure legend:Fig. 4a, Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/06/03 2020/06/17 rogid:RohltRPJbmvNaZQpQQDxwwUkjd0694009 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rigid:bKaEeWxqmc+DK4SOFVxQedr9P5g false tandem tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P59637 uniprotkb:P59594 intact:EBI-25487741|uniprotkb:Q7TA13|uniprotkb:Q7TFA8 intact:EBI-15582614|intact:EBI-16063777|uniprotkb:Q6QU82|uniprotkb:Q7T696|uniprotkb:Q7TA19|uniprotkb:Q7TFA2|uniprotkb:Q7TFB1|uniprotkb:Q80BV6 psi-mi:vemp_sars(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name) psi-mi:spike_sars(display_long)|uniprotkb:S(gene name)|psi-mi:S(display_short)|uniprotkb:E2(gene name synonym)|uniprotkb:Peplomer protein(gene name synonym)|uniprotkb:2(orf name) psi-mi:"MI:0676"(tandem affinity purification) Alvarez et al. (2010) pubmed:20409569|imex:IM-28038 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25635717|imex:IM-28038-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|rcsb pdb:7NTJ|go:"GO:0000139"(Golgi membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044377|rcsb pdb:2MM4|rcsb pdb:5X29|rcsb pdb:5XER|rcsb pdb:5XES|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR043506|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683683|reactome:R-HSA-9683701|refseq:NP_828854.1 go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039587"(suppression by virus of host tetherin activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044173"(host cell endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046789"(host cell surface receptor binding)|go:"GO:0046813"(receptor-mediated virion attachment to host cell)|go:"GO:0055036"(virion membrane)|go:"GO:0075509"(endocytosis involved in viral entry into host cell)|interpro:IPR002552(Coronavirus S2 glycoprotein)|interpro:IPR018548|interpro:IPR032500|interpro:IPR036326|interpro:IPR042578|interpro:IPR043002|interpro:IPR043473|interpro:IPR043607|interpro:IPR044341|interpro:IPR044370|interpro:IPR044873|interpro:IPR044874|rcsb pdb:1Q4Z|rcsb pdb:1T7G|rcsb pdb:1U4K|rcsb pdb:1WNC|rcsb pdb:1WYY|rcsb pdb:1XJP|rcsb pdb:1ZV7|rcsb pdb:1ZV8|rcsb pdb:1ZVB|rcsb pdb:2AJF|rcsb pdb:2BEQ|rcsb pdb:2BEZ|rcsb pdb:2DD8|rcsb pdb:2FXP|rcsb pdb:2GHV|rcsb pdb:2GHW|rcsb pdb:2RUM|rcsb pdb:2RUN|rcsb pdb:2RUO|rcsb pdb:3BGF|rcsb pdb:3D0G|rcsb pdb:3D0H|rcsb pdb:3D0I|rcsb pdb:3SCI|rcsb pdb:3SCJ|rcsb pdb:3SCK|rcsb pdb:3SCL|rcsb pdb:5WRG|rcsb pdb:5X4S|rcsb pdb:5X58|rcsb pdb:5X5B|rcsb pdb:5XJK|rcsb pdb:5XLR|rcsb pdb:5ZVM|rcsb pdb:6ACC|rcsb pdb:6ACD|rcsb pdb:6ACG|rcsb pdb:6ACK|rcsb pdb:6CRV|rcsb pdb:6CRW|rcsb pdb:6CRX|rcsb pdb:6CRZ|rcsb pdb:6CS0|rcsb pdb:6CS1|rcsb pdb:6CS2|rcsb pdb:6M3W|rcsb pdb:6NB6|rcsb pdb:6NB7|rcsb pdb:6VW1|rcsb pdb:6WAQ|rcsb pdb:7JN5|rcsb pdb:6ACJ|dip:DIP-29105N|reactome:R-HSA-9679509|reactome:R-HSA-9683686|reactome:R-HSA-9683701|refseq:NP_828851.1|reactome:R-HSA-9678110 - - - figure legend:Fig. 4a, Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/06/03 2020/06/17 rogid:RohltRPJbmvNaZQpQQDxwwUkjd0694009 rogid:H4uZUhfNNQNcF4O+7CmC50IoAi8694009 rigid:bKaEeWxqmc+DK4SOFVxQedr9P5g false tandem tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P59637 uniprotkb:P0C6X7-PRO_0000037311 intact:EBI-25487741|uniprotkb:Q7TA13|uniprotkb:Q7TFA8 intact:EBI-25474079 psi-mi:vemp_sars(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name) psi-mi:p0c6x7-pro_0000037311(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0676"(tandem affinity purification) Alvarez et al. (2010) pubmed:20409569|imex:IM-28038 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25635717|imex:IM-28038-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|rcsb pdb:7NTJ|go:"GO:0000139"(Golgi membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044377|rcsb pdb:2MM4|rcsb pdb:5X29|rcsb pdb:5XER|rcsb pdb:5XES|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR043506|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683683|reactome:R-HSA-9683701|refseq:NP_828854.1 intact:EBI-7843867(chain-parent) - - chain-seq-start:819|chain-seq-end:2740 figure legend:Fig. 4a, Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/06/03 2020/06/17 rogid:RohltRPJbmvNaZQpQQDxwwUkjd0694009 rogid:NKZ5d0D2HjefhmJQwgHz+M1lSt8694009 rigid:bKaEeWxqmc+DK4SOFVxQedr9P5g false tandem tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P0C6X7-PRO_0000037311 uniprotkb:P59637 intact:EBI-25474079 intact:EBI-25487741|uniprotkb:Q7TA13|uniprotkb:Q7TFA8 psi-mi:p0c6x7-pro_0000037311(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:vemp_sars(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Alvarez et al. (2010) pubmed:20409569|imex:IM-28038 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25638253|imex:IM-28038-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent) go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|rcsb pdb:7NTJ|go:"GO:0000139"(Golgi membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044377|rcsb pdb:2MM4|rcsb pdb:5X29|rcsb pdb:5XER|rcsb pdb:5XES|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR043506|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683683|reactome:R-HSA-9683701|refseq:NP_828854.1 - chain-seq-start:819|chain-seq-end:2740 - figure legend:Fig. 4b|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-vero_e6)|taxid:9534(chlae-vero_e6 cells) - 2020/06/03 2020/06/04 rogid:NKZ5d0D2HjefhmJQwgHz+M1lSt8694009 rogid:RohltRPJbmvNaZQpQQDxwwUkjd0694009 rigid:EGe5f6nncQL948R/k7eH3zQbxsk false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P0C6X7-PRO_0000037311 uniprotkb:P59637 intact:EBI-25474079 intact:EBI-25487741|uniprotkb:Q7TA13|uniprotkb:Q7TFA8 psi-mi:p0c6x7-pro_0000037311(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:vemp_sars(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Alvarez et al. (2010) pubmed:20409569|imex:IM-28038 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25638257|imex:IM-28038-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent) go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|rcsb pdb:7NTJ|go:"GO:0000139"(Golgi membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044377|rcsb pdb:2MM4|rcsb pdb:5X29|rcsb pdb:5XER|rcsb pdb:5XES|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR043506|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683683|reactome:R-HSA-9683701|refseq:NP_828854.1 - chain-seq-start:819|chain-seq-end:2740 - figure legend:Fig. 4b|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-vero_e6)|taxid:9534(chlae-vero_e6 cells) - 2020/06/03 2020/06/04 rogid:NKZ5d0D2HjefhmJQwgHz+M1lSt8694009 rogid:RohltRPJbmvNaZQpQQDxwwUkjd0694009 rigid:EGe5f6nncQL948R/k7eH3zQbxsk false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P0C6X7-PRO_0000037311 uniprotkb:P59637 intact:EBI-25474079 intact:EBI-25487741|uniprotkb:Q7TA13|uniprotkb:Q7TFA8 psi-mi:p0c6x7-pro_0000037311(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:vemp_sars(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Alvarez et al. (2010) pubmed:20409569|imex:IM-28038 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25638451|imex:IM-28038-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent) go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|rcsb pdb:7NTJ|go:"GO:0000139"(Golgi membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044377|rcsb pdb:2MM4|rcsb pdb:5X29|rcsb pdb:5XER|rcsb pdb:5XES|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR043506|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683683|reactome:R-HSA-9683701|refseq:NP_828854.1 - chain-seq-start:819|chain-seq-end:2740 - figure legend:Figs. 5a-b, 6a-b|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/06/03 2020/06/17 rogid:NKZ5d0D2HjefhmJQwgHz+M1lSt8694009 rogid:RohltRPJbmvNaZQpQQDxwwUkjd0694009 rigid:EGe5f6nncQL948R/k7eH3zQbxsk false sufficient binding region:1-183(IPR038083)|necessary binding region:1-183(IPR038083)|biotin tag:?-? ha tag:c-c|flag tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P59637 uniprotkb:P0C6X7-PRO_0000037311 intact:EBI-25487741|uniprotkb:Q7TA13|uniprotkb:Q7TFA8 intact:EBI-25474079 psi-mi:vemp_sars(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name) psi-mi:p0c6x7-pro_0000037311(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0663"(confocal microscopy) Alvarez et al. (2010) pubmed:20409569|imex:IM-28038 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-25638553|imex:IM-28038-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|rcsb pdb:7NTJ|go:"GO:0000139"(Golgi membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044377|rcsb pdb:2MM4|rcsb pdb:5X29|rcsb pdb:5XER|rcsb pdb:5XES|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR043506|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683683|reactome:R-HSA-9683701|refseq:NP_828854.1 intact:EBI-7843867(chain-parent) go:"GO:0048471"(perinuclear region of cytoplasm) - chain-seq-start:819|chain-seq-end:2740 figure legend:Fig. 7.|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-vero_e6)|taxid:9534(chlae-vero_e6 cells) - 2020/06/03 2020/06/04 rogid:RohltRPJbmvNaZQpQQDxwwUkjd0694009 rogid:NKZ5d0D2HjefhmJQwgHz+M1lSt8694009 rigid:EGe5f6nncQL948R/k7eH3zQbxsk false ha tag:c-c|flag tag:c-c - - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry)