#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P03434 uniprotkb:P03429 intact:EBI-22234925 intact:EBI-22179471 psi-mi:pa_i68a6(display_long)|uniprotkb:RNA-directed RNA polymerase subunit P2(gene name synonym)|uniprotkb:PA(gene name)|psi-mi:PA(display_short) psi-mi:pb2_i68a6(display_long)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short) psi-mi:"MI:0410"(3D electron microscopy) Fan et al. (2019) pubmed:31485076|imex:IM-27487 taxid:384505("Influenza A virus (strain NT60)")|taxid:384505("Influenza A virus (strain A/Northern Territory/60/1968 H3N2)") taxid:384505("Influenza A virus (strain NT60)")|taxid:384505("Influenza A virus (strain A/Northern Territory/60/1968 H3N2)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-22234981|emdb:4661|imex:IM-27487-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0075526"(cap snatching)|rcsb pdb:6QPG|rcsb pdb:6QX3|rcsb pdb:6QX8|rcsb pdb:6QXE|rcsb pdb:6RR7|interpro:IPR037534|interpro:IPR001009(RNA-directed RNA polymerase, P2 subunit)|interpro:IPR038372 rcsb pdb:6QNW|rcsb pdb:6QPG|rcsb pdb:6QX3|rcsb pdb:6QX8|rcsb pdb:6QXE|rcsb pdb:6RR7|interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching) - - - figure legend:Ext Fig 4,5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2019/10/31 2019/12/03 rogid:41D84WKHqOi9JwWBjWg9hCU/5KA384505 rogid:6CdPxzEaYmaefzppFHHyv784Wi4384505 rigid:4C838PGmq1Fvg07P/6XUa1mlv08 false - - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P03434 uniprotkb:Q910D6 intact:EBI-22234925 intact:EBI-22234965 psi-mi:pa_i68a6(display_long)|uniprotkb:RNA-directed RNA polymerase subunit P2(gene name synonym)|uniprotkb:PA(gene name)|psi-mi:PA(display_short) psi-mi:rdrp_i68a4(display_long)|uniprotkb:PB1(gene name)|psi-mi:PB1(display_short)|uniprotkb:Polymerase basic protein 1(gene name synonym)|uniprotkb:RNA-directed RNA polymerase subunit P1(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Fan et al. (2019) pubmed:31485076|imex:IM-27487 taxid:384505("Influenza A virus (strain NT60)")|taxid:384505("Influenza A virus (strain A/Northern Territory/60/1968 H3N2)") taxid:506350(i68a4)|taxid:506350("Influenza A virus (strain A/Hong Kong/1/1968 H3N2)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-22234981|emdb:4661|imex:IM-27487-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0075526"(cap snatching)|rcsb pdb:6QPG|rcsb pdb:6QX3|rcsb pdb:6QX8|rcsb pdb:6QXE|rcsb pdb:6RR7|interpro:IPR037534|interpro:IPR001009(RNA-directed RNA polymerase, P2 subunit)|interpro:IPR038372 go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019083"(viral transcription)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6QX3|interpro:IPR007099(RNA-directed RNA polymerase, negative-strand RNA virus)|interpro:IPR001407(RNA-dependent RNA polymerase, PB1 subunit, Influenza-ype) - - - figure legend:Ext Fig 4,5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2019/10/31 2019/12/03 rogid:41D84WKHqOi9JwWBjWg9hCU/5KA384505 rogid:eabXv+rzpUjJlnHNMBgpUAaPL3I506350 rigid:4C838PGmq1Fvg07P/6XUa1mlv08 false - - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:P03434 uniprotkb:P03429 intact:EBI-22234925 intact:EBI-22179471 psi-mi:pa_i68a6(display_long)|uniprotkb:RNA-directed RNA polymerase subunit P2(gene name synonym)|uniprotkb:PA(gene name)|psi-mi:PA(display_short) psi-mi:pb2_i68a6(display_long)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short) psi-mi:"MI:0410"(3D electron microscopy) Fan et al. (2019) pubmed:31485076|imex:IM-27487 taxid:384505("Influenza A virus (strain NT60)")|taxid:384505("Influenza A virus (strain A/Northern Territory/60/1968 H3N2)") taxid:384505("Influenza A virus (strain NT60)")|taxid:384505("Influenza A virus (strain A/Northern Territory/60/1968 H3N2)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-22235114|emdb:EMD-4986|emdb:EMD-4663|emdb:EMD-4666|imex:IM-27487-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0075526"(cap snatching)|rcsb pdb:6QPG|rcsb pdb:6QX3|rcsb pdb:6QX8|rcsb pdb:6QXE|rcsb pdb:6RR7|interpro:IPR037534|interpro:IPR001009(RNA-directed RNA polymerase, P2 subunit)|interpro:IPR038372 rcsb pdb:6QNW|rcsb pdb:6QPG|rcsb pdb:6QX3|rcsb pdb:6QX8|rcsb pdb:6QXE|rcsb pdb:6RR7|interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching) - - - figure legend:Ext fig 7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2019/10/31 2019/12/02 rogid:41D84WKHqOi9JwWBjWg9hCU/5KA384505 rogid:6CdPxzEaYmaefzppFHHyv784Wi4384505 rigid:f1kZOeSqSSDPDBCVRK+Rv8MV0Zk false - - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:P03434 uniprotkb:P03432 intact:EBI-22234925 intact:EBI-22179451 psi-mi:pa_i68a6(display_long)|uniprotkb:RNA-directed RNA polymerase subunit P2(gene name synonym)|uniprotkb:PA(gene name)|psi-mi:PA(display_short) psi-mi:rdrp_i68a6(display_long)|uniprotkb:Polymerase basic protein 1(gene name synonym)|uniprotkb:RNA-directed RNA polymerase subunit P1(gene name synonym)|uniprotkb:PB1(gene name)|psi-mi:PB1(display_short) psi-mi:"MI:0410"(3D electron microscopy) Fan et al. (2019) pubmed:31485076|imex:IM-27487 taxid:384505("Influenza A virus (strain NT60)")|taxid:384505("Influenza A virus (strain A/Northern Territory/60/1968 H3N2)") taxid:384505("Influenza A virus (strain NT60)")|taxid:384505("Influenza A virus (strain A/Northern Territory/60/1968 H3N2)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-22235114|emdb:EMD-4986|emdb:EMD-4663|emdb:EMD-4666|imex:IM-27487-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0075526"(cap snatching)|rcsb pdb:6QPG|rcsb pdb:6QX3|rcsb pdb:6QX8|rcsb pdb:6QXE|rcsb pdb:6RR7|interpro:IPR037534|interpro:IPR001009(RNA-directed RNA polymerase, P2 subunit)|interpro:IPR038372 rcsb pdb:6QNW|rcsb pdb:6QPG|rcsb pdb:6QX8|rcsb pdb:6QXE|rcsb pdb:6RR7|interpro:IPR007099(RNA-directed RNA polymerase, negative-strand RNA virus)|interpro:IPR001407(RNA-dependent RNA polymerase, PB1 subunit, Influenza-ype)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019083"(viral transcription)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus) - - - figure legend:Ext fig 7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2019/10/31 2019/12/02 rogid:41D84WKHqOi9JwWBjWg9hCU/5KA384505 rogid:ieNGHREkbQEz1OewjcOpz4q4guM384505 rigid:f1kZOeSqSSDPDBCVRK+Rv8MV0Zk false - - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:O36432 uniprotkb:O36431 intact:EBI-22234996 intact:EBI-22235091 psi-mi:pa_inbp9(display_long)|uniprotkb:RNA-directed RNA polymerase subunit P2(gene name synonym)|uniprotkb:PA(gene name)|psi-mi:PA(display_short) psi-mi:pb2_inbp9(display_long)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short) psi-mi:"MI:0410"(3D electron microscopy) Fan et al. (2019) pubmed:31485076|imex:IM-27487 taxid:408929("Influenza B virus (strain B/Panama/45/1990)")|taxid:408929("Influenza B virus (strain B/Panama/45/1990)") taxid:408929("Influenza B virus (strain B/Panama/45/1990)")|taxid:408929("Influenza B virus (strain B/Panama/45/1990)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-22235954|emdb:EMD-4660|imex:IM-27487-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0075526"(cap snatching)|rcsb pdb:6QWL|interpro:IPR037534|interpro:IPR001009(RNA-directed RNA polymerase, P2 subunit)|interpro:IPR038372 go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|rcsb pdb:6QWL|interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258 - - - figure legend:Ext fig 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2019/10/31 2019/12/03 rogid:KawvwvAFtD93fDCiZw3ZF7vS1IQ408929 rogid:842o7u8cM9G27dkajrdgz+zbUZ4408929 rigid:m6IowYzgtAquymx1WcbUODg6E5o false - - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:O36432 uniprotkb:O36430 intact:EBI-22234996 intact:EBI-22235013 psi-mi:pa_inbp9(display_long)|uniprotkb:RNA-directed RNA polymerase subunit P2(gene name synonym)|uniprotkb:PA(gene name)|psi-mi:PA(display_short) psi-mi:rdrp_inbp9(display_long)|uniprotkb:Polymerase basic protein 1(gene name synonym)|uniprotkb:RNA-directed RNA polymerase subunit P1(gene name synonym)|uniprotkb:PB1(gene name)|psi-mi:PB1(display_short) psi-mi:"MI:0410"(3D electron microscopy) Fan et al. (2019) pubmed:31485076|imex:IM-27487 taxid:408929("Influenza B virus (strain B/Panama/45/1990)")|taxid:408929("Influenza B virus (strain B/Panama/45/1990)") taxid:408929("Influenza B virus (strain B/Panama/45/1990)")|taxid:408929("Influenza B virus (strain B/Panama/45/1990)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-22235954|emdb:EMD-4660|imex:IM-27487-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0075526"(cap snatching)|rcsb pdb:6QWL|interpro:IPR037534|interpro:IPR001009(RNA-directed RNA polymerase, P2 subunit)|interpro:IPR038372 go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019083"(viral transcription)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6QWL|interpro:IPR007099(RNA-directed RNA polymerase, negative-strand RNA virus)|interpro:IPR001407(RNA-dependent RNA polymerase, PB1 subunit, Influenza-ype) - - - figure legend:Ext fig 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2019/10/31 2019/12/03 rogid:KawvwvAFtD93fDCiZw3ZF7vS1IQ408929 rogid:X3dTmS/pgXuNj0PKEFEegKlXZgw408929 rigid:m6IowYzgtAquymx1WcbUODg6E5o false - - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:P03429 uniprotkb:Q1AR05 intact:EBI-22179471 intact:EBI-22179433 psi-mi:pb2_i68a6(display_long)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short) psi-mi:q1ar05_9infa(display_long)|uniprotkb:RNA-directed RNA polymerase subunit P2(gene name synonym)|uniprotkb:PA(gene name)|psi-mi:PA(display_short) psi-mi:"MI:0114"(x-ray crystallography) Fan et al. (2019) pubmed:31485076|imex:IM-27487 taxid:384505("Influenza A virus (strain NT60)")|taxid:384505("Influenza A virus (strain A/Northern Territory/60/1968 H3N2)") taxid:370128("A/Northern Territory/60/1968(H3N2)")|taxid:370128(Influenza A virus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-22179494|imex:IM-27487-1|wwpdb:6QNW - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6QNW|rcsb pdb:6QPG|rcsb pdb:6QX3|rcsb pdb:6QX8|rcsb pdb:6QXE|rcsb pdb:6RR7|interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching) rcsb pdb:6QNW|interpro:IPR037534|interpro:IPR001009(RNA-directed RNA polymerase, P2 subunit)|interpro:IPR038372|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0075526"(cap snatching) - - - figure legend:Fig 1A. Ext Tab 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2019/10/31 2019/10/31 rogid:6CdPxzEaYmaefzppFHHyv784Wi4384505 rogid:41D84WKHqOi9JwWBjWg9hCU/5KA370128 rigid:qvQIMG7Zc3C1+jjcXleetveLiI0 false - - 2 2 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:P03429 uniprotkb:P03432 intact:EBI-22179471 intact:EBI-22179451 psi-mi:pb2_i68a6(display_long)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short) psi-mi:rdrp_i68a6(display_long)|uniprotkb:Polymerase basic protein 1(gene name synonym)|uniprotkb:RNA-directed RNA polymerase subunit P1(gene name synonym)|uniprotkb:PB1(gene name)|psi-mi:PB1(display_short) psi-mi:"MI:0114"(x-ray crystallography) Fan et al. (2019) pubmed:31485076|imex:IM-27487 taxid:384505("Influenza A virus (strain NT60)")|taxid:384505("Influenza A virus (strain A/Northern Territory/60/1968 H3N2)") taxid:384505("Influenza A virus (strain NT60)")|taxid:384505("Influenza A virus (strain A/Northern Territory/60/1968 H3N2)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-22179494|imex:IM-27487-1|wwpdb:6QNW - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6QNW|rcsb pdb:6QPG|rcsb pdb:6QX3|rcsb pdb:6QX8|rcsb pdb:6QXE|rcsb pdb:6RR7|interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching) rcsb pdb:6QNW|rcsb pdb:6QPG|rcsb pdb:6QX8|rcsb pdb:6QXE|rcsb pdb:6RR7|interpro:IPR007099(RNA-directed RNA polymerase, negative-strand RNA virus)|interpro:IPR001407(RNA-dependent RNA polymerase, PB1 subunit, Influenza-ype)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019083"(viral transcription)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus) - - - figure legend:Fig 1A. Ext Tab 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2019/10/31 2019/10/31 rogid:6CdPxzEaYmaefzppFHHyv784Wi4384505 rogid:ieNGHREkbQEz1OewjcOpz4q4guM384505 rigid:qvQIMG7Zc3C1+jjcXleetveLiI0 false - - 2 2 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:D3YNB5 uniprotkb:D3YNB6 intact:EBI-22179532 intact:EBI-22179517 psi-mi:d3ynb5_9infa(display_long)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short) psi-mi:d3ynb6_9infa(display_long)|uniprotkb:Polymerase basic protein 1(gene name synonym)|uniprotkb:RNA-directed RNA polymerase subunit P1(gene name synonym)|uniprotkb:PB1(gene name)|psi-mi:PB1(display_short) psi-mi:"MI:0114"(x-ray crystallography) Fan et al. (2019) pubmed:31485076|imex:IM-27487 taxid:274827("A/duck/Fujian/01/2002(H5N1)")|taxid:274827(Influenza A virus) taxid:274827("A/duck/Fujian/01/2002(H5N1)")|taxid:274827(Influenza A virus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-22179547|imex:IM-27487-3|wwpdb:6QPF - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6QPF|interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching) rcsb pdb:6QPF|interpro:IPR007099(RNA-directed RNA polymerase, negative-strand RNA virus)|interpro:IPR001407(RNA-dependent RNA polymerase, PB1 subunit, Influenza-ype)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019083"(viral transcription)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus) - - - figure legend:Fig 1a. Ex Data Tab2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2019/10/31 2019/10/31 rogid:oWsDbCtzc2XfgNCr9NXTHCjwL2Y274827 rogid:iUx5z/5CERs7Xn4rTQLFl0E1z6o274827 rigid:JtVkap/mIz2u7Iss/PSOuHhdTCg false - - 2 2 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:D3YNB5 uniprotkb:D3YNB8 intact:EBI-22179532 intact:EBI-22179501 psi-mi:d3ynb5_9infa(display_long)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short) psi-mi:d3ynb8_9infa(display_long)|uniprotkb:RNA-directed RNA polymerase subunit P2(gene name synonym)|uniprotkb:PA(gene name)|psi-mi:PA(display_short) psi-mi:"MI:0114"(x-ray crystallography) Fan et al. (2019) pubmed:31485076|imex:IM-27487 taxid:274827("A/duck/Fujian/01/2002(H5N1)")|taxid:274827(Influenza A virus) taxid:274827("A/duck/Fujian/01/2002(H5N1)")|taxid:274827(Influenza A virus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-22179547|imex:IM-27487-3|wwpdb:6QPF - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6QPF|interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching) rcsb pdb:6QPF|interpro:IPR037534|interpro:IPR001009(RNA-directed RNA polymerase, P2 subunit)|interpro:IPR038372|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0075526"(cap snatching) - - - figure legend:Fig 1a. Ex Data Tab2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2019/10/31 2019/10/31 rogid:oWsDbCtzc2XfgNCr9NXTHCjwL2Y274827 rogid:v3z9ohDVuyxLHLtpaXqgvB+htec274827 rigid:JtVkap/mIz2u7Iss/PSOuHhdTCg false - - 2 2 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:P03434 uniprotkb:P03429 intact:EBI-22234925 intact:EBI-22179471 psi-mi:pa_i68a6(display_long)|uniprotkb:RNA-directed RNA polymerase subunit P2(gene name synonym)|uniprotkb:PA(gene name)|psi-mi:PA(display_short) psi-mi:pb2_i68a6(display_long)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short) psi-mi:"MI:0114"(x-ray crystallography) Fan et al. (2019) pubmed:31485076|imex:IM-27487 taxid:384505("Influenza A virus (strain NT60)")|taxid:384505("Influenza A virus (strain A/Northern Territory/60/1968 H3N2)") taxid:384505("Influenza A virus (strain NT60)")|taxid:384505("Influenza A virus (strain A/Northern Territory/60/1968 H3N2)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-22234946|wwpdb:6QPG|imex:IM-27487-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0075526"(cap snatching)|rcsb pdb:6QPG|rcsb pdb:6QX3|rcsb pdb:6QX8|rcsb pdb:6QXE|rcsb pdb:6RR7|interpro:IPR037534|interpro:IPR001009(RNA-directed RNA polymerase, P2 subunit)|interpro:IPR038372 rcsb pdb:6QNW|rcsb pdb:6QPG|rcsb pdb:6QX3|rcsb pdb:6QX8|rcsb pdb:6QXE|rcsb pdb:6RR7|interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching) - - - figure legend:Ext fig 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2019/10/31 2019/12/02 rogid:41D84WKHqOi9JwWBjWg9hCU/5KA384505 rogid:6CdPxzEaYmaefzppFHHyv784Wi4384505 rigid:f1kZOeSqSSDPDBCVRK+Rv8MV0Zk false - - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:P03434 uniprotkb:P03432 intact:EBI-22234925 intact:EBI-22179451 psi-mi:pa_i68a6(display_long)|uniprotkb:RNA-directed RNA polymerase subunit P2(gene name synonym)|uniprotkb:PA(gene name)|psi-mi:PA(display_short) psi-mi:rdrp_i68a6(display_long)|uniprotkb:Polymerase basic protein 1(gene name synonym)|uniprotkb:RNA-directed RNA polymerase subunit P1(gene name synonym)|uniprotkb:PB1(gene name)|psi-mi:PB1(display_short) psi-mi:"MI:0114"(x-ray crystallography) Fan et al. (2019) pubmed:31485076|imex:IM-27487 taxid:384505("Influenza A virus (strain NT60)")|taxid:384505("Influenza A virus (strain A/Northern Territory/60/1968 H3N2)") taxid:384505("Influenza A virus (strain NT60)")|taxid:384505("Influenza A virus (strain A/Northern Territory/60/1968 H3N2)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-22234946|wwpdb:6QPG|imex:IM-27487-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0075526"(cap snatching)|rcsb pdb:6QPG|rcsb pdb:6QX3|rcsb pdb:6QX8|rcsb pdb:6QXE|rcsb pdb:6RR7|interpro:IPR037534|interpro:IPR001009(RNA-directed RNA polymerase, P2 subunit)|interpro:IPR038372 rcsb pdb:6QNW|rcsb pdb:6QPG|rcsb pdb:6QX8|rcsb pdb:6QXE|rcsb pdb:6RR7|interpro:IPR007099(RNA-directed RNA polymerase, negative-strand RNA virus)|interpro:IPR001407(RNA-dependent RNA polymerase, PB1 subunit, Influenza-ype)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019083"(viral transcription)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus) - - - figure legend:Ext fig 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2019/10/31 2019/12/02 rogid:41D84WKHqOi9JwWBjWg9hCU/5KA384505 rogid:ieNGHREkbQEz1OewjcOpz4q4guM384505 rigid:f1kZOeSqSSDPDBCVRK+Rv8MV0Zk false - - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:P03434 uniprotkb:P03429 intact:EBI-22234925 intact:EBI-22179471 psi-mi:pa_i68a6(display_long)|uniprotkb:RNA-directed RNA polymerase subunit P2(gene name synonym)|uniprotkb:PA(gene name)|psi-mi:PA(display_short) psi-mi:pb2_i68a6(display_long)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short) psi-mi:"MI:0114"(x-ray crystallography) Fan et al. (2019) pubmed:31485076|imex:IM-27487 taxid:384505("Influenza A virus (strain NT60)")|taxid:384505("Influenza A virus (strain A/Northern Territory/60/1968 H3N2)") taxid:384505("Influenza A virus (strain NT60)")|taxid:384505("Influenza A virus (strain A/Northern Territory/60/1968 H3N2)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-22235979|wwpdb:6qx3|imex:IM-27487-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0075526"(cap snatching)|rcsb pdb:6QPG|rcsb pdb:6QX3|rcsb pdb:6QX8|rcsb pdb:6QXE|rcsb pdb:6RR7|interpro:IPR037534|interpro:IPR001009(RNA-directed RNA polymerase, P2 subunit)|interpro:IPR038372 rcsb pdb:6QNW|rcsb pdb:6QPG|rcsb pdb:6QX3|rcsb pdb:6QX8|rcsb pdb:6QXE|rcsb pdb:6RR7|interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching) - - - figure legend:Ext Fig 4,5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2019/10/31 2019/12/03 rogid:41D84WKHqOi9JwWBjWg9hCU/5KA384505 rogid:6CdPxzEaYmaefzppFHHyv784Wi4384505 rigid:4C838PGmq1Fvg07P/6XUa1mlv08 false - - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P03434 uniprotkb:Q910D6 intact:EBI-22234925 intact:EBI-22234965 psi-mi:pa_i68a6(display_long)|uniprotkb:RNA-directed RNA polymerase subunit P2(gene name synonym)|uniprotkb:PA(gene name)|psi-mi:PA(display_short) psi-mi:rdrp_i68a4(display_long)|uniprotkb:PB1(gene name)|psi-mi:PB1(display_short)|uniprotkb:Polymerase basic protein 1(gene name synonym)|uniprotkb:RNA-directed RNA polymerase subunit P1(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Fan et al. (2019) pubmed:31485076|imex:IM-27487 taxid:384505("Influenza A virus (strain NT60)")|taxid:384505("Influenza A virus (strain A/Northern Territory/60/1968 H3N2)") taxid:506350(i68a4)|taxid:506350("Influenza A virus (strain A/Hong Kong/1/1968 H3N2)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-22235979|wwpdb:6qx3|imex:IM-27487-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0075526"(cap snatching)|rcsb pdb:6QPG|rcsb pdb:6QX3|rcsb pdb:6QX8|rcsb pdb:6QXE|rcsb pdb:6RR7|interpro:IPR037534|interpro:IPR001009(RNA-directed RNA polymerase, P2 subunit)|interpro:IPR038372 go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019083"(viral transcription)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6QX3|interpro:IPR007099(RNA-directed RNA polymerase, negative-strand RNA virus)|interpro:IPR001407(RNA-dependent RNA polymerase, PB1 subunit, Influenza-ype) - - - figure legend:Ext Fig 4,5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2019/10/31 2019/12/03 rogid:41D84WKHqOi9JwWBjWg9hCU/5KA384505 rogid:eabXv+rzpUjJlnHNMBgpUAaPL3I506350 rigid:4C838PGmq1Fvg07P/6XUa1mlv08 false - - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:O36432 uniprotkb:O36431 intact:EBI-22234996 intact:EBI-22235091 psi-mi:pa_inbp9(display_long)|uniprotkb:RNA-directed RNA polymerase subunit P2(gene name synonym)|uniprotkb:PA(gene name)|psi-mi:PA(display_short) psi-mi:pb2_inbp9(display_long)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short) psi-mi:"MI:0114"(x-ray crystallography) Fan et al. (2019) pubmed:31485076|imex:IM-27487 taxid:408929("Influenza B virus (strain B/Panama/45/1990)")|taxid:408929("Influenza B virus (strain B/Panama/45/1990)") taxid:408929("Influenza B virus (strain B/Panama/45/1990)")|taxid:408929("Influenza B virus (strain B/Panama/45/1990)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-22235990|wwpdb:6qwl|imex:IM-27487-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0075526"(cap snatching)|rcsb pdb:6QWL|interpro:IPR037534|interpro:IPR001009(RNA-directed RNA polymerase, P2 subunit)|interpro:IPR038372 go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|rcsb pdb:6QWL|interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258 - - - figure legend:Ext fig 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2019/10/31 2019/12/03 rogid:KawvwvAFtD93fDCiZw3ZF7vS1IQ408929 rogid:842o7u8cM9G27dkajrdgz+zbUZ4408929 rigid:m6IowYzgtAquymx1WcbUODg6E5o false - - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:O36432 uniprotkb:O36430 intact:EBI-22234996 intact:EBI-22235013 psi-mi:pa_inbp9(display_long)|uniprotkb:RNA-directed RNA polymerase subunit P2(gene name synonym)|uniprotkb:PA(gene name)|psi-mi:PA(display_short) psi-mi:rdrp_inbp9(display_long)|uniprotkb:Polymerase basic protein 1(gene name synonym)|uniprotkb:RNA-directed RNA polymerase subunit P1(gene name synonym)|uniprotkb:PB1(gene name)|psi-mi:PB1(display_short) psi-mi:"MI:0114"(x-ray crystallography) Fan et al. (2019) pubmed:31485076|imex:IM-27487 taxid:408929("Influenza B virus (strain B/Panama/45/1990)")|taxid:408929("Influenza B virus (strain B/Panama/45/1990)") taxid:408929("Influenza B virus (strain B/Panama/45/1990)")|taxid:408929("Influenza B virus (strain B/Panama/45/1990)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-22235990|wwpdb:6qwl|imex:IM-27487-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0075526"(cap snatching)|rcsb pdb:6QWL|interpro:IPR037534|interpro:IPR001009(RNA-directed RNA polymerase, P2 subunit)|interpro:IPR038372 go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019083"(viral transcription)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6QWL|interpro:IPR007099(RNA-directed RNA polymerase, negative-strand RNA virus)|interpro:IPR001407(RNA-dependent RNA polymerase, PB1 subunit, Influenza-ype) - - - figure legend:Ext fig 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2019/10/31 2019/12/03 rogid:KawvwvAFtD93fDCiZw3ZF7vS1IQ408929 rogid:X3dTmS/pgXuNj0PKEFEegKlXZgw408929 rigid:m6IowYzgtAquymx1WcbUODg6E5o false - - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:P03434 uniprotkb:P03429 intact:EBI-22234925 intact:EBI-22179471 psi-mi:pa_i68a6(display_long)|uniprotkb:RNA-directed RNA polymerase subunit P2(gene name synonym)|uniprotkb:PA(gene name)|psi-mi:PA(display_short) psi-mi:pb2_i68a6(display_long)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short) psi-mi:"MI:0114"(x-ray crystallography) Fan et al. (2019) pubmed:31485076|imex:IM-27487 taxid:384505("Influenza A virus (strain NT60)")|taxid:384505("Influenza A virus (strain A/Northern Territory/60/1968 H3N2)") taxid:384505("Influenza A virus (strain NT60)")|taxid:384505("Influenza A virus (strain A/Northern Territory/60/1968 H3N2)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-22235997|wwpdb:6rr7|wwpdb:6qxe|wwpdb:6qx8|imex:IM-27487-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0075526"(cap snatching)|rcsb pdb:6QPG|rcsb pdb:6QX3|rcsb pdb:6QX8|rcsb pdb:6QXE|rcsb pdb:6RR7|interpro:IPR037534|interpro:IPR001009(RNA-directed RNA polymerase, P2 subunit)|interpro:IPR038372 rcsb pdb:6QNW|rcsb pdb:6QPG|rcsb pdb:6QX3|rcsb pdb:6QX8|rcsb pdb:6QXE|rcsb pdb:6RR7|interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching) - - - figure legend:Ext fig 7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2019/10/31 2019/12/03 rogid:41D84WKHqOi9JwWBjWg9hCU/5KA384505 rogid:6CdPxzEaYmaefzppFHHyv784Wi4384505 rigid:f1kZOeSqSSDPDBCVRK+Rv8MV0Zk false - - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:P03434 uniprotkb:P03432 intact:EBI-22234925 intact:EBI-22179451 psi-mi:pa_i68a6(display_long)|uniprotkb:RNA-directed RNA polymerase subunit P2(gene name synonym)|uniprotkb:PA(gene name)|psi-mi:PA(display_short) psi-mi:rdrp_i68a6(display_long)|uniprotkb:Polymerase basic protein 1(gene name synonym)|uniprotkb:RNA-directed RNA polymerase subunit P1(gene name synonym)|uniprotkb:PB1(gene name)|psi-mi:PB1(display_short) psi-mi:"MI:0114"(x-ray crystallography) Fan et al. (2019) pubmed:31485076|imex:IM-27487 taxid:384505("Influenza A virus (strain NT60)")|taxid:384505("Influenza A virus (strain A/Northern Territory/60/1968 H3N2)") taxid:384505("Influenza A virus (strain NT60)")|taxid:384505("Influenza A virus (strain A/Northern Territory/60/1968 H3N2)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-22235997|wwpdb:6rr7|wwpdb:6qxe|wwpdb:6qx8|imex:IM-27487-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0075526"(cap snatching)|rcsb pdb:6QPG|rcsb pdb:6QX3|rcsb pdb:6QX8|rcsb pdb:6QXE|rcsb pdb:6RR7|interpro:IPR037534|interpro:IPR001009(RNA-directed RNA polymerase, P2 subunit)|interpro:IPR038372 rcsb pdb:6QNW|rcsb pdb:6QPG|rcsb pdb:6QX8|rcsb pdb:6QXE|rcsb pdb:6RR7|interpro:IPR007099(RNA-directed RNA polymerase, negative-strand RNA virus)|interpro:IPR001407(RNA-dependent RNA polymerase, PB1 subunit, Influenza-ype)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019083"(viral transcription)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus) - - - figure legend:Ext fig 7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2019/10/31 2019/12/03 rogid:41D84WKHqOi9JwWBjWg9hCU/5KA384505 rogid:ieNGHREkbQEz1OewjcOpz4q4guM384505 rigid:f1kZOeSqSSDPDBCVRK+Rv8MV0Zk false - - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)