#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P55087	uniprotkb:Q5T9L3-2	intact:EBI-10104898|uniprotkb:P78564|ensembl:ENSP00000372654|ensembl:ENSP00000500720	intact:EBI-21508346|ensembl:ENSP00000346829	psi-mi:aqp4_human(display_long)|uniprotkb:AQP4(gene name)|psi-mi:AQP4(display_short)|uniprotkb:Mercurial-insensitive water channel(gene name synonym)|uniprotkb:WCH4(gene name synonym)	psi-mi:q5t9l3-2(display_long)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Petko et al. (2019)	pubmed:31286866|imex:IM-27806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22114456|imex:IM-27806-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001641.1|refseq:NP_004019.1|ensembl:ENSG00000171885(gene)|ensembl:ENST00000383168(transcript)|ensembl:ENST00000672188(transcript)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006833"(water transport)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009992"(cellular water homeostasis)|go:"GO:0010008"(endosome membrane)|go:"GO:0015250"(water channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030104"(water homeostasis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0050891"(multicellular organismal water homeostasis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090660"(cerebrospinal fluid circulation)|go:"GO:0097450"(astrocyte end-foot)|interpro:IPR000425(Major intrinsic protein)|interpro:IPR022357|interpro:IPR023271|interpro:IPR034294|rcsb pdb:3GD8|reactome:R-HSA-432040|reactome:R-HSA-432047|dip:DIP-48842N	ensembl:ENSG00000116729(gene)|ensembl:ENST00000354777(transcript)|intact:EBI-2868748(isoform-parent)	-	-	-	figure legend:Figs 2, 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2019/10/08	2019/10/29	rogid:emloJNSTB0zSwtP91cSKBBr4PA89606	rogid:suSstC7Z1iuclhX7sh47FceaErg9606	rigid:dsLMD/br6rFGiC3KNaj0g0PiM8g	false	nub:?-?|sufficient binding region:1-184	cub:?-?|sufficient binding region:505-543	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5T742	uniprotkb:Q5T9L3-2	intact:EBI-20865573|uniprotkb:A1L424|uniprotkb:Q96NM5	intact:EBI-21508346|ensembl:ENSP00000346829	psi-mi:zfas1_human(display_long)|uniprotkb:ZNF22-AS1(gene name)|psi-mi:ZNF22-AS1(display_short)|uniprotkb:C10orf25(gene name synonym)|uniprotkb:ZNF22 antisense RNA 1(gene name synonym)	psi-mi:q5t9l3-2(display_long)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Petko et al. (2019)	pubmed:31286866|imex:IM-27806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22114465|imex:IM-27806-39	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005576"(extracellular region)|refseq:NP_001034469.2|refseq:XP_016871384.1	ensembl:ENSG00000116729(gene)|ensembl:ENST00000354777(transcript)|intact:EBI-2868748(isoform-parent)	-	-	-	figure legend:Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2019/10/08	2019/10/21	rogid:LflkbwoJqv8ftu6WTtkY/jeG/h49606	rogid:suSstC7Z1iuclhX7sh47FceaErg9606	rigid:lIloUFp/5QCFT4cEkiXGEGHIlms	false	nub:?-?	cub:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96D05	uniprotkb:Q5T9L3-2	intact:EBI-2548784|ensembl:ENSP00000362376	intact:EBI-21508346|ensembl:ENSP00000346829	psi-mi:f241b_human(display_long)|uniprotkb:FAM241B(gene name)|psi-mi:FAM241B(display_short)|uniprotkb:C10orf35(gene name synonym)	psi-mi:q5t9l3-2(display_long)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Petko et al. (2019)	pubmed:31286866|imex:IM-27806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22114469|imex:IM-27806-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000171224(gene)|ensembl:ENST00000373279(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR027953|mint:Q96D05|refseq:XP_011537757.1|refseq:NP_660349.1|refseq:XP_005269663.1|refseq:XP_005269665.1|refseq:XP_016871325.1	ensembl:ENSG00000116729(gene)|ensembl:ENST00000354777(transcript)|intact:EBI-2868748(isoform-parent)	-	-	-	figure legend:Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2019/10/08	2019/10/21	rogid:2Iylns4G5knUSJCXAPnLUE9laUU9606	rogid:suSstC7Z1iuclhX7sh47FceaErg9606	rigid:Oh/Nv4s0y9fRVxoe44QzZrOXggk	false	nub:?-?	cub:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P08962	uniprotkb:Q5T9L3-2	intact:EBI-762053|uniprotkb:Q5TZP3|uniprotkb:Q9UCG6|uniprotkb:Q8N6Z9|uniprotkb:F8VZE2|ensembl:ENSP00000257857|ensembl:ENSP00000393502|ensembl:ENSP00000447730|ensembl:ENSP00000449337	intact:EBI-21508346|ensembl:ENSP00000346829	psi-mi:cd63_human(display_long)|uniprotkb:Melanoma-associated antigen ME491(gene name synonym)|uniprotkb:Ocular melanoma-associated antigen(gene name synonym)|uniprotkb:OMA81H(gene name synonym)|uniprotkb:Granulophysin(gene name synonym)|uniprotkb:Tetraspanin-30(gene name synonym)|uniprotkb:Lysosomal-associated membrane protein 3(gene name synonym)|uniprotkb:CD63(gene name)|psi-mi:CD63(display_short)|uniprotkb:MLA1(gene name synonym)|uniprotkb:TSPAN30(gene name synonym)|uniprotkb:Lysosome integral membrane protein 1(gene name synonym)	psi-mi:q5t9l3-2(display_long)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Petko et al. (2019)	pubmed:31286866|imex:IM-27806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22114473|imex:IM-27806-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001771.1|refseq:NP_001244330.1|refseq:NP_001244318.1|refseq:NP_001244319.1|refseq:NP_001244320.1|refseq:NP_001244329.1|refseq:NP_001254627.1|refseq:NP_001244321.1|ensembl:ENSG00000135404(gene)|ensembl:ENST00000257857(transcript)|go:"GO:1900746"(regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR018503|interpro:IPR042028|mint:P08962|reactome:R-HSA-114608|reactome:R-HSA-6798695|go:"GO:0097487"(multivesicular body, internal vesicle)|ensembl:ENST00000420846(transcript)|ensembl:ENST00000549117(transcript)|ensembl:ENST00000552692(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016477"(cell migration)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031904"(endosome lumen)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0042470"(melanosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048757"(pigment granule maturation)|go:"GO:0070062"(extracellular exosome)	ensembl:ENSG00000116729(gene)|ensembl:ENST00000354777(transcript)|intact:EBI-2868748(isoform-parent)	-	-	-	figure legend:Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2019/10/08	2019/10/21	rogid:stCGi5kkTMIdO84qSwjmjpUwwvs9606	rogid:suSstC7Z1iuclhX7sh47FceaErg9606	rigid:G+4xbm2dGlKeVtVW+oAOQI2RkbU	false	nub:?-?|sufficient binding region:123-197	cub:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9P003	uniprotkb:Q5T9L3-2	intact:EBI-1044341|ensembl:ENSP00000420443|uniprotkb:Q9H0X8|uniprotkb:A8K1Q8|uniprotkb:B2R553	intact:EBI-21508346|ensembl:ENSP00000346829	psi-mi:cnih4_human(display_long)|uniprotkb:CNIH4(gene name)|psi-mi:CNIH4(display_short)|uniprotkb:Cornichon family AMPA receptor auxiliary protein 4(gene name synonym)|uniprotkb:HSPC163(orf name)	psi-mi:q5t9l3-2(display_long)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Petko et al. (2019)	pubmed:31286866|imex:IM-27806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22114477|imex:IM-27806-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000465271(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0031730"(CCR5 chemokine receptor binding)|interpro:IPR003377(Cornichon)|ensembl:ENSG00000143771(gene)|refseq:NP_054903.1|refseq:NP_001264126.1	ensembl:ENSG00000116729(gene)|ensembl:ENST00000354777(transcript)|intact:EBI-2868748(isoform-parent)	-	-	-	figure legend:Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2019/10/08	2019/10/21	rogid:vKqBlBp/B2XQikBgv7RZH8IymEo9606	rogid:suSstC7Z1iuclhX7sh47FceaErg9606	rigid:6Mljgcs+BeY4/kY0cCOYTB12Zts	false	nub:?-?|sufficient binding region:1-138	cub:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q01959	uniprotkb:Q5T9L3-2	intact:EBI-6661445|ensembl:ENSP00000270349|ensembl:ENSP00000479597|uniprotkb:A2RUN4|uniprotkb:Q14996	intact:EBI-21508346|ensembl:ENSP00000346829	psi-mi:sc6a3_human(display_long)|uniprotkb:SLC6A3(gene name)|psi-mi:SLC6A3(display_short)|uniprotkb:DAT1(gene name synonym)|uniprotkb:Solute carrier family 6 member 3(gene name synonym)	psi-mi:q5t9l3-2(display_long)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Petko et al. (2019)	pubmed:31286866|imex:IM-27806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22114481|imex:IM-27806-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0015844"(monoamine transport)|go:"GO:0015872"(dopamine transport)|go:"GO:0007626"(locomotory behavior)|go:"GO:0015874"(norepinephrine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0008504"(monoamine transmembrane transporter activity)|go:"GO:0009986"(cell surface)|go:"GO:0016600"(flotillin complex)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0030424"(axon)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0035094"(response to nicotine)|go:"GO:0035240"(dopamine binding)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042220"(response to cocaine)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042420"(dopamine catabolic process)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051591"(response to cAMP)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0090494"(dopamine uptake)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0010039"(response to iron ion)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1990384"(hyaloid vascular plexus regression)|interpro:IPR000175("Sodium:neurotransmitter symporter")|interpro:IPR002436("Sodium:neurotransmitter symporter, dopamine")|interpro:IPR037272|mint:Q01959|reactome:R-HSA-379401|reactome:R-HSA-442660|reactome:R-HSA-5619081|reactome:R-HSA-5660724|ensembl:ENSG00000142319(gene)|ensembl:ENSG00000276996(gene)|ensembl:ENST00000270349(transcript)|ensembl:ENST00000621716(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005330"("dopamine:sodium symporter activity")|go:"GO:0005334"("norepinephrine:sodium symporter activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007568"(aging)|go:"GO:0007595"(lactation)|go:"GO:0007608"(sensory perception of smell)|refseq:NP_001035.1|dip:DIP-41827N	ensembl:ENSG00000116729(gene)|ensembl:ENST00000354777(transcript)|intact:EBI-2868748(isoform-parent)	-	-	-	figure legend:Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2019/10/08	2019/10/21	rogid:mQKSGpeovNv4Sg8T2E3A8rVB2aY9606	rogid:suSstC7Z1iuclhX7sh47FceaErg9606	rigid:FnjRqnc2ddM2rmePyMoJFkkZdpU	false	nub:?-?|sufficient binding region:1-343	cub:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O94777	uniprotkb:Q5T9L3-2	intact:EBI-9097061|uniprotkb:Q5XKK9|uniprotkb:Q6FGH3|ensembl:ENSP00000322181	intact:EBI-21508346|ensembl:ENSP00000346829	psi-mi:dpm2_human(display_long)|uniprotkb:DPM2(gene name)|psi-mi:DPM2(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 2(gene name synonym)|uniprotkb:My026(orf name)	psi-mi:q5t9l3-2(display_long)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Petko et al. (2019)	pubmed:31286866|imex:IM-27806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22114485|imex:IM-27806-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003854.1|ensembl:ENSG00000136908(gene)|ensembl:ENST00000314392(transcript)|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0019348"(dolichol metabolic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035269"(protein O-linked mannosylation)|interpro:IPR009914(Dolichol phosphate-mannose biosynthesis regulatory)|reactome:R-HSA-162699|reactome:R-HSA-162710|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377	ensembl:ENSG00000116729(gene)|ensembl:ENST00000354777(transcript)|intact:EBI-2868748(isoform-parent)	-	-	-	figure legend:Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2019/10/08	2019/10/21	rogid:b1kR+UX6Sfr1TcOpQ0D4M3+xy8M9606	rogid:suSstC7Z1iuclhX7sh47FceaErg9606	rigid:8CX1iOtc8HS0qefY8HDX2u2o0/Y	false	nub:?-?	cub:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NPA0	uniprotkb:Q5T9L3-2	intact:EBI-6309137|ensembl:ENSP00000256545|uniprotkb:B2RC00|uniprotkb:Q96ED5	intact:EBI-21508346|ensembl:ENSP00000346829	psi-mi:emc7_human(display_long)|uniprotkb:EMC7(gene name)|psi-mi:EMC7(display_short)|uniprotkb:C11orf3(gene name synonym)|uniprotkb:C15orf24(gene name synonym)|uniprotkb:HT022(orf name)|uniprotkb:UNQ905/PRO1926(orf name)	psi-mi:q5t9l3-2(display_long)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Petko et al. (2019)	pubmed:31286866|imex:IM-27806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22114493|imex:IM-27806-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000134153(gene)|ensembl:ENST00000256545(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR019008|interpro:IPR039163|rcsb pdb:1B0G|rcsb pdb:1LP9|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2UWE|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|refseq:NP_064539.1	ensembl:ENSG00000116729(gene)|ensembl:ENST00000354777(transcript)|intact:EBI-2868748(isoform-parent)	-	-	-	figure legend:Figs 2, 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2019/10/08	2019/10/21	rogid:XBg97fKNpvbssNf6YFewsWDmiBE9606	rogid:suSstC7Z1iuclhX7sh47FceaErg9606	rigid:IM4cLBsHU+BXySXMPC4fQfVitcE	false	nub:?-?|sufficient binding region:37-242	cub:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UN67	uniprotkb:Q5T9L3-2	intact:EBI-6308942|ensembl:ENSP00000239446|uniprotkb:Q96T99	intact:EBI-21508346|ensembl:ENSP00000346829	psi-mi:pcdba_human(display_long)|uniprotkb:PCDHB10(gene name)|psi-mi:PCDHB10(display_short)|uniprotkb:UNQ1906/PRO4352(orf name)	psi-mi:q5t9l3-2(display_long)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Petko et al. (2019)	pubmed:31286866|imex:IM-27806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22114497|imex:IM-27806-41	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000120324(gene)|ensembl:ENST00000239446(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007416"(synapse assembly)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0045202"(synapse)|interpro:IPR002126(Cadherin)|interpro:IPR013164(Cadherin, N-terminal)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR032455|refseq:NP_061753.1	ensembl:ENSG00000116729(gene)|ensembl:ENST00000354777(transcript)|intact:EBI-2868748(isoform-parent)	-	-	-	figure legend:Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2019/10/08	2019/10/21	rogid:eDBO6rRJdTj1TzDUyXxX+iDJywo9606	rogid:suSstC7Z1iuclhX7sh47FceaErg9606	rigid:xRe+sk+ZTD+hUtYXqS665bMU5UA	false	nub:?-?	cub:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q7Z7B1	uniprotkb:Q5T9L3-2	intact:EBI-21505660|ensembl:ENSP00000480021|ensembl:ENSP00000481144|ensembl:ENSP00000482202|ensembl:ENSP00000488033|uniprotkb:Q8N9G3	intact:EBI-21508346|ensembl:ENSP00000346829	psi-mi:pigw_human(display_long)|uniprotkb:PIGW(gene name)|psi-mi:PIGW(display_short)	psi-mi:q5t9l3-2(display_long)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Petko et al. (2019)	pubmed:31286866|imex:IM-27806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22114501|imex:IM-27806-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000275600(gene)|ensembl:ENSG00000277161(gene)|ensembl:ENST00000614443(transcript)|ensembl:ENST00000616581(transcript)|ensembl:ENST00000620233(transcript)|ensembl:ENST00000631508(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006505"(GPI anchor metabolic process)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0008374"(O-acyltransferase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016254"(preassembly of GPI anchor in ER membrane)|go:"GO:0032216"(glucosaminyl-phosphatidylinositol O-acyltransferase activity)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR009447(GWT1)|reactome:R-HSA-162710|refseq:NP_001333683.1|refseq:NP_001333684.1|refseq:NP_848612.2	ensembl:ENSG00000116729(gene)|ensembl:ENST00000354777(transcript)|intact:EBI-2868748(isoform-parent)	-	-	-	figure legend:Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2019/10/08	2019/10/21	rogid:1AGBg5TjHW5YNjN7IeJR7/7Foj49606	rogid:suSstC7Z1iuclhX7sh47FceaErg9606	rigid:0Xa5Bn1ZyCi6G98n09Q+dhyUYkQ	false	nub:?-?|sufficient binding region:417-504	cub:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P48436	uniprotkb:Q5T9L3-2	intact:EBI-3920028|ensembl:ENSP00000245479|uniprotkb:Q53Y80	intact:EBI-21508346|ensembl:ENSP00000346829	psi-mi:sox9_human(display_long)|uniprotkb:SOX9(gene name)|psi-mi:SOX9(display_short)	psi-mi:q5t9l3-2(display_long)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Petko et al. (2019)	pubmed:31286866|imex:IM-27806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22114505|imex:IM-27806-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000125398(gene)|ensembl:ENST00000245479(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001502"(cartilage condensation)|go:"GO:0001503"(ossification)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001708"(cell fate specification)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001942"(hair follicle development)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0002683"(negative regulation of immune system process)|go:"GO:0003170"(heart valve development)|go:"GO:0003179"(heart valve morphogenesis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003188"(heart valve formation)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003413"(chondrocyte differentiation involved in endochondral bone morphogenesis)|go:"GO:0003415"(chondrocyte hypertrophy)|go:"GO:0003430"(growth plate cartilage chondrocyte growth)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0014032"(neural crest cell development)|go:"GO:0014036"(neural crest cell fate specification)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0019100"(male germ-line sex determination)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0030850"(prostate gland development)|go:"GO:0030857"(negative regulation of epithelial cell differentiation)|go:"GO:0030858"(positive regulation of epithelial cell differentiation)|go:"GO:0030879"(mammary gland development)|go:"GO:0030903"(notochord development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032808"(lacrimal gland development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0035622"(intrahepatic bile duct development)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046322"(negative regulation of fatty acid oxidation)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051216"(cartilage development)|go:"GO:0060008"(Sertoli cell differentiation)|go:"GO:0060009"(Sertoli cell development)|go:"GO:0060018"(astrocyte fate commitment)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060174"(limb bud formation)|go:"GO:0060221"(retinal rod cell differentiation)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060487"(lung epithelial cell differentiation)|go:"GO:0060517"(epithelial cell proliferation involved in prostatic bud elongation)|go:"GO:0060532"(bronchus cartilage development)|go:"GO:0060534"(trachea cartilage development)|go:"GO:0060729"(intestinal epithelial structure maintenance)|go:"GO:0060784"(regulation of cell proliferation involved in tissue homeostasis)|go:"GO:0061036"(positive regulation of cartilage development)|go:"GO:0061046"(regulation of branching involved in lung morphogenesis)|go:"GO:0061138"(morphogenesis of a branching epithelium)|go:"GO:0061145"(lung smooth muscle development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070168"(negative regulation of biomineral tissue development)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070384"(Harderian gland development)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071504"(cellular response to heparin)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0072034"(renal vesicle induction)|go:"GO:0072190"(ureter urothelium development)|go:"GO:0072193"(ureter smooth muscle cell differentiation)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0072289"(metanephric nephron tubule formation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090184"(positive regulation of kidney development)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:0097065"(anterior head development)|go:"GO:0097157"(pre-mRNA intronic binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1901203"(positive regulation of extracellular matrix assembly)|go:"GO:1902732"(positive regulation of chondrocyte proliferation)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1904864"(negative regulation of beta-catenin-TCF complex assembly)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000020"(positive regulation of male gonad development)|go:"GO:2000138"(positive regulation of cell proliferation involved in heart morphogenesis)|go:"GO:2000741"(positive regulation of mesenchymal stem cell differentiation)|go:"GO:2000794"(regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:2001054"(negative regulation of mesenchymal cell apoptotic process)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022151|interpro:IPR029548|interpro:IPR036910|rcsb pdb:1S9M|rcsb pdb:1SX9|rcsb pdb:4EUW|reactome:R-HSA-3769402|reactome:R-HSA-8878166|reactome:R-HSA-9690406|refseq:NP_000337.1|dip:DIP-61319N	ensembl:ENSG00000116729(gene)|ensembl:ENST00000354777(transcript)|intact:EBI-2868748(isoform-parent)	-	-	-	figure legend:Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2019/10/08	2019/10/21	rogid:9tMOPJUNgC89D1SdrN0b4yCXRUk9606	rogid:suSstC7Z1iuclhX7sh47FceaErg9606	rigid:aLBQOb7v5fDu2c1cPW3AvcdyVR0	false	nub:?-?|sufficient binding region:381-458	cub:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y6G1	uniprotkb:Q5T9L3-2	intact:EBI-2800360|uniprotkb:B2R552|ensembl:ENSP00000211314	intact:EBI-21508346|ensembl:ENSP00000346829	psi-mi:tm14a_human(display_long)|uniprotkb:C6orf73(gene name synonym)|uniprotkb:PTD011(orf name)|uniprotkb:TMEM14A(gene name)|psi-mi:TMEM14A(display_short)	psi-mi:q5t9l3-2(display_long)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Petko et al. (2019)	pubmed:31286866|imex:IM-27806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22114510|imex:IM-27806-57	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000211314(transcript)|refseq:NP_054770.1|ensembl:ENSG00000096092(gene)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|interpro:IPR005349(Protein of unknown function UPF0136, Transmembrane)|interpro:IPR044890|mint:Q9Y6G1|rcsb pdb:2LOO|rcsb pdb:2LOP|go:"GO:0005789"(endoplasmic reticulum membrane)	ensembl:ENSG00000116729(gene)|ensembl:ENST00000354777(transcript)|intact:EBI-2868748(isoform-parent)	-	-	-	figure legend:Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2019/10/08	2019/10/21	rogid:nrvzpoAjkgMJIDiqVIVa5b3jLsQ9606	rogid:suSstC7Z1iuclhX7sh47FceaErg9606	rigid:u0DfqLzeEvDSzxIkyQdyIP3Vkvg	false	nub:?-?|sufficient binding region:1-99	cub:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9H6X4	uniprotkb:Q5T9L3-2	intact:EBI-22084643|uniprotkb:Q08AK4|uniprotkb:Q6PJN3|ensembl:ENSP00000312615	intact:EBI-21508346|ensembl:ENSP00000346829	psi-mi:tm134_human(display_long)|uniprotkb:TMEM134(gene name)|psi-mi:TMEM134(display_short)	psi-mi:q5t9l3-2(display_long)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Petko et al. (2019)	pubmed:31286866|imex:IM-27806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22114514|imex:IM-27806-59	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001072118.1|refseq:NP_001072119.1|refseq:NP_079400.1|ensembl:ENSG00000172663(gene)|ensembl:ENST00000308022(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR008590(Protein of unknown function DUF872, eukaryotic)|interpro:IPR039714	ensembl:ENSG00000116729(gene)|ensembl:ENST00000354777(transcript)|intact:EBI-2868748(isoform-parent)	-	-	-	figure legend:Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2019/10/08	2019/10/21	rogid:lutWi4WCwdkEPwUXGiONGVN/xvY9606	rogid:suSstC7Z1iuclhX7sh47FceaErg9606	rigid:MO1cO8RjrMP31l3Z0+67mSyVixo	false	nub:?-?|sufficient binding region:1-165	cub:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NX00	uniprotkb:Q5T9L3-2	intact:EBI-2514588|ensembl:ENSP00000253047|uniprotkb:Q9BU41	intact:EBI-21508346|ensembl:ENSP00000346829	psi-mi:tm160_human(display_long)|uniprotkb:TMEM160(gene name)|psi-mi:TMEM160(display_short)	psi-mi:q5t9l3-2(display_long)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Petko et al. (2019)	pubmed:31286866|imex:IM-27806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22114519|imex:IM-27806-61	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000130748(gene)|ensembl:ENST00000253047(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR026801|refseq:NP_060324.1	ensembl:ENSG00000116729(gene)|ensembl:ENST00000354777(transcript)|intact:EBI-2868748(isoform-parent)	-	-	-	figure legend:Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2019/10/08	2019/10/21	rogid:5PuVgGSb9lQAD5/1RS6csGdai0Q9606	rogid:suSstC7Z1iuclhX7sh47FceaErg9606	rigid:5BtSzppIsJ7PDn/yAYczUVbVHbM	false	nub:?-?|sufficient binding region:17-187	cub:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96A57	uniprotkb:Q5T9L3-2	intact:EBI-723971|uniprotkb:D3DVZ9|uniprotkb:Q0VGC8|uniprotkb:Q5TDS5|uniprotkb:Q96ES2|uniprotkb:Q9P0A7|uniprotkb:B2RDM8|ensembl:ENSP00000202834|ensembl:ENSP00000368579|ensembl:ENSP00000368581|ensembl:ENSP00000368585|ensembl:ENSP00000368588|ensembl:ENSP00000368601	intact:EBI-21508346|ensembl:ENSP00000346829	psi-mi:tm230_human(display_long)|uniprotkb:TMEM230(gene name)|psi-mi:TMEM230(display_short)|uniprotkb:C20orf30(gene name synonym)|uniprotkb:HSPC274(orf name)|uniprotkb:UNQ2432/PRO4992(orf name)	psi-mi:q5t9l3-2(display_long)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Petko et al. (2019)	pubmed:31286866|imex:IM-27806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22114525|imex:IM-27806-43	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009923.1|refseq:NP_001009924.1|refseq:NP_001009925.1|refseq:NP_054864.3|refseq:NP_001317913.1|refseq:NP_001317914.1|refseq:NP_001317915.1|refseq:XP_016883325.1|ensembl:ENSG00000089063(gene)|ensembl:ENST00000202834(transcript)|ensembl:ENST00000379277(transcript)|ensembl:ENST00000379279(transcript)|ensembl:ENST00000379283(transcript)|ensembl:ENST00000379286(transcript)|ensembl:ENST00000379299(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0055037"(recycling endosome)|interpro:IPR008590(Protein of unknown function DUF872, eukaryotic)|interpro:IPR044234	ensembl:ENSG00000116729(gene)|ensembl:ENST00000354777(transcript)|intact:EBI-2868748(isoform-parent)	-	-	-	figure legend:Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2019/10/08	2019/10/21	rogid:n9vIcFyub2Fl+lSnmvcQ1DrA7PE9606	rogid:suSstC7Z1iuclhX7sh47FceaErg9606	rigid:dvXIcJznfYBPFpx1eYI1g6yrBGQ	false	nub:?-?|sufficient binding region:6-120	cub:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96B49	uniprotkb:Q5T9L3-2	intact:EBI-10826510|uniprotkb:B2DG15|uniprotkb:Q9UH52|ensembl:ENSP00000381856|ensembl:ENSP00000381859	intact:EBI-21508346|ensembl:ENSP00000346829	psi-mi:tom6_human(display_long)|uniprotkb:TOMM6(gene name)|psi-mi:TOMM6(display_short)|uniprotkb:Overexpressed breast tumor protein(gene name synonym)|uniprotkb:Translocase of outer membrane 6 kDa subunit homolog(gene name synonym)|uniprotkb:OBTP(gene name synonym)|uniprotkb:TOM6(gene name synonym)	psi-mi:q5t9l3-2(display_long)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Petko et al. (2019)	pubmed:31286866|imex:IM-27806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22114529|imex:IM-27806-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001127965.1|ensembl:ENSG00000214736(gene)|ensembl:ENST00000398881(transcript)|ensembl:ENST00000398884(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0015031"(protein transport)|interpro:IPR029182|mint:Q96B49|rcsb pdb:7CK6|rcsb pdb:7CP9|reactome:R-HSA-1268020|reactome:R-HSA-5205685	ensembl:ENSG00000116729(gene)|ensembl:ENST00000354777(transcript)|intact:EBI-2868748(isoform-parent)	-	-	-	figure legend:Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2019/10/08	2019/10/21	rogid:j3q/LBZ1XHboUAcHka+T8XtNsIM9606	rogid:suSstC7Z1iuclhX7sh47FceaErg9606	rigid:Alk+oALe4OFoVtXJPPqBSZPumEA	false	nub:?-?	cub:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NYZ1	uniprotkb:Q5T9L3-2	intact:EBI-11343401|uniprotkb:A8K448|uniprotkb:Q9Y3E6|uniprotkb:Q96HK5|ensembl:ENSP00000305654	intact:EBI-21508346|ensembl:ENSP00000346829	psi-mi:tv23b_human(display_long)|uniprotkb:TVP23B(gene name)|psi-mi:TVP23B(display_short)|uniprotkb:FAM18B(gene name synonym)|uniprotkb:FAM18B1(gene name synonym)|uniprotkb:CGI-148(orf name)|uniprotkb:NPD008(orf name)	psi-mi:q5t9l3-2(display_long)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Petko et al. (2019)	pubmed:31286866|imex:IM-27806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22114533|imex:IM-27806-29	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001303848.1|refseq:NP_001303849.1|refseq:NP_001303850.1|refseq:NP_001303851.1|refseq:NP_001303852.1|refseq:NP_001303853.1|refseq:NP_057162.4|ensembl:ENSG00000171928(gene)|ensembl:ENST00000307767(transcript)|go:"GO:0009306"(protein secretion)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|interpro:IPR008564(Protein of unknown function DUF846, eukaryotic)	ensembl:ENSG00000116729(gene)|ensembl:ENST00000354777(transcript)|intact:EBI-2868748(isoform-parent)	-	-	-	figure legend:Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2019/10/08	2019/10/21	rogid:gxyJHSx9RYFnyhZFDzRLW8QwzmU9606	rogid:suSstC7Z1iuclhX7sh47FceaErg9606	rigid:OTy+2oFX0oiu/lcimd1IZFUjL2o	false	nub:?-?|sufficient binding region:34-142	cub:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96EC8	uniprotkb:Q5T9L3-2	intact:EBI-751210|uniprotkb:Q5JP08|uniprotkb:B4E1U7|uniprotkb:G5E997|ensembl:ENSP00000417573	intact:EBI-21508346|ensembl:ENSP00000346829	psi-mi:yipf6_human(display_long)|uniprotkb:YIP1 family member 6(gene name synonym)|uniprotkb:YIPF6(gene name)|psi-mi:YIPF6(display_short)	psi-mi:q5t9l3-2(display_long)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Petko et al. (2019)	pubmed:31286866|imex:IM-27806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22114548|imex:IM-27806-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_776195.2|refseq:NP_001182143.1|ensembl:ENSG00000181704(gene)|ensembl:ENST00000462683(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0060576"(intestinal epithelial cell development)|interpro:IPR006977(Yip1 domain)|mint:Q96EC8|reactome:R-HSA-432722	ensembl:ENSG00000116729(gene)|ensembl:ENST00000354777(transcript)|intact:EBI-2868748(isoform-parent)	-	-	-	figure legend:Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2019/10/08	2019/10/21	rogid:mfHkmdPyX5lK/euzg8v1Ydikf5w9606	rogid:suSstC7Z1iuclhX7sh47FceaErg9606	rigid:sY0nC8IFpY2+35fJ/4wSf+cGPpo	false	nub:?-?|sufficient binding region:1-236	cub:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q6ZNB7	uniprotkb:Q5T9L3-2	intact:EBI-18509181|uniprotkb:A4D114|uniprotkb:A6NCH5|ensembl:ENSP00000341662	intact:EBI-21508346|ensembl:ENSP00000346829	psi-mi:alkmo_human(display_long)|uniprotkb:Transmembrane protein 195(gene name synonym)|uniprotkb:AGMO(gene name)|psi-mi:AGMO(display_short)|uniprotkb:TMEM195(gene name synonym)	psi-mi:q5t9l3-2(display_long)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Petko et al. (2019)	pubmed:31286866|imex:IM-27806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22118747|imex:IM-27806-49	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001004320.1|ensembl:ENSG00000187546(gene)|ensembl:ENST00000342526(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006643"(membrane lipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0050479"(glyceryl-ether monooxygenase activity)|interpro:IPR006694(Fatty acid hydroxylase)|reactome:R-HSA-75109|go:"GO:0046485"(ether lipid metabolic process)	ensembl:ENSG00000116729(gene)|ensembl:ENST00000354777(transcript)|intact:EBI-2868748(isoform-parent)	-	-	-	figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2019/10/08	2019/10/29	rogid:wy+ShH8vBzS15EJFthHNMOFqCs89606	rogid:suSstC7Z1iuclhX7sh47FceaErg9606	rigid:WUgkpG4YK8K+hgGgG5fYa8XJyrw	false	nub:?-?	cub:?-?|sufficient binding region:505-543	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P51674	uniprotkb:Q5T9L3-2	intact:EBI-7187133|ensembl:ENSP00000280187|ensembl:ENSP00000377268|intact:UNK-5379643|uniprotkb:Q92602|uniprotkb:E9PHI5|uniprotkb:B7Z642	intact:EBI-21508346|ensembl:ENSP00000346829	psi-mi:gpm6a_human(display_long)|uniprotkb:GPM6A(gene name)|psi-mi:GPM6A(display_short)|uniprotkb:M6A(gene name synonym)	psi-mi:q5t9l3-2(display_long)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Petko et al. (2019)	pubmed:31286866|imex:IM-27806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22118757|imex:IM-27806-51	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000150625(gene)|ensembl:ENST00000280187(transcript)|ensembl:ENST00000393658(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003407"(neural retina development)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007416"(synapse assembly)|go:"GO:0009617"(response to bacterium)|go:"GO:0030175"(filopodium)|go:"GO:0031175"(neuron projection development)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044295"(axonal growth cone)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR001614(Myelin proteolipid protein PLP)|interpro:IPR018237|refseq:NP_001248377.1|refseq:NP_963885.1|refseq:NP_005268.1|refseq:NP_963886.1	ensembl:ENSG00000116729(gene)|ensembl:ENST00000354777(transcript)|intact:EBI-2868748(isoform-parent)	-	comment:mint|comment:homomint	-	figure legend:fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2019/10/08	2019/10/29	rogid:6h/p/+l8WRhJ9HsGcbxleQuDtSo9606	rogid:suSstC7Z1iuclhX7sh47FceaErg9606	rigid:FRkywS9tuRji0uVWiVzJJmUgvOU	false	nub:?-?	cub:?-?|sufficient binding region:507-543	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96D31	uniprotkb:Q5T9L3-2	intact:EBI-2291476|uniprotkb:Q3MHV3|uniprotkb:Q6DHX2|uniprotkb:Q96BP7|uniprotkb:Q96K71|ensembl:ENSP00000482568	intact:EBI-21508346|ensembl:ENSP00000346829	psi-mi:crcm1_human(display_long)|uniprotkb:ORAI1(gene name)|psi-mi:ORAI1(display_short)|uniprotkb:CRACM1(gene name synonym)|uniprotkb:TMEM142A(gene name synonym)|uniprotkb:Protein orai-1(gene name synonym)|uniprotkb:Transmembrane protein 142A(gene name synonym)	psi-mi:q5t9l3-2(display_long)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Petko et al. (2019)	pubmed:31286866|imex:IM-27806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22118767|imex:IM-27806-35	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_116179.2|go:"GO:0070588"(calcium ion transmembrane transport)|interpro:IPR012446(Protein of unknown function DUF1650)|interpro:IPR038350|rcsb pdb:2MAK|rcsb pdb:4EHQ|reactome:R-HSA-139853|reactome:R-HSA-5578775|reactome:R-HSA-983695|ensembl:ENSG00000276045(gene)|ensembl:ENST00000617316(transcript)|go:"GO:0002115"(store-operated calcium entry)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015279"(store-operated calcium channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0034704"(calcium channel complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045121"(membrane raft)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0061180"(mammary gland epithelium development)|go:"GO:0070509"(calcium ion import)|dip:DIP-46289N	ensembl:ENSG00000116729(gene)|ensembl:ENST00000354777(transcript)|intact:EBI-2868748(isoform-parent)	-	-	-	figure legend:fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2019/10/08	2019/10/29	rogid:VXcTrF/8sZA01XGUFZwvu75L7Kw9606	rogid:suSstC7Z1iuclhX7sh47FceaErg9606	rigid:Jr/yueXRyxvImL4PegCDBBcKbnc	false	nub:?-?	cub:?-?|sufficient binding region:507-543	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P55087	uniprotkb:Q5T9L3-1	intact:EBI-10104898|uniprotkb:P78564|ensembl:ENSP00000372654|ensembl:ENSP00000500720	intact:EBI-22114623|ensembl:ENSP00000262348	psi-mi:aqp4_human(display_long)|uniprotkb:AQP4(gene name)|psi-mi:AQP4(display_short)|uniprotkb:Mercurial-insensitive water channel(gene name synonym)|uniprotkb:WCH4(gene name synonym)	psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Petko et al. (2019)	pubmed:31286866|imex:IM-27806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22118788|imex:IM-27806-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001641.1|refseq:NP_004019.1|ensembl:ENSG00000171885(gene)|ensembl:ENST00000383168(transcript)|ensembl:ENST00000672188(transcript)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006833"(water transport)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009992"(cellular water homeostasis)|go:"GO:0010008"(endosome membrane)|go:"GO:0015250"(water channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030104"(water homeostasis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0050891"(multicellular organismal water homeostasis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090660"(cerebrospinal fluid circulation)|go:"GO:0097450"(astrocyte end-foot)|interpro:IPR000425(Major intrinsic protein)|interpro:IPR022357|interpro:IPR023271|interpro:IPR034294|rcsb pdb:3GD8|reactome:R-HSA-432040|reactome:R-HSA-432047|dip:DIP-48842N	ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent)	-	-	-	figure legend:Figs 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2019/10/08	2019/10/29	rogid:emloJNSTB0zSwtP91cSKBBr4PA89606	rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606	rigid:g8T9s/Y6VKE2rvXk6G339NmfOQs	false	nub:?-?|sufficient binding region:1-184	cub:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NPA0	uniprotkb:Q5T9L3-1	intact:EBI-6309137|ensembl:ENSP00000256545|uniprotkb:B2RC00|uniprotkb:Q96ED5	intact:EBI-22114623|ensembl:ENSP00000262348	psi-mi:emc7_human(display_long)|uniprotkb:EMC7(gene name)|psi-mi:EMC7(display_short)|uniprotkb:C11orf3(gene name synonym)|uniprotkb:C15orf24(gene name synonym)|uniprotkb:HT022(orf name)|uniprotkb:UNQ905/PRO1926(orf name)	psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Petko et al. (2019)	pubmed:31286866|imex:IM-27806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22118797|imex:IM-27806-37	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000134153(gene)|ensembl:ENST00000256545(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR019008|interpro:IPR039163|rcsb pdb:1B0G|rcsb pdb:1LP9|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2UWE|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|refseq:NP_064539.1	ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent)	-	-	-	figure legend:Fig 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2019/10/08	2019/10/29	rogid:XBg97fKNpvbssNf6YFewsWDmiBE9606	rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606	rigid:E4SLLC2dFVPKkpGiAGNlYfzuPp0	false	nub:?-?|sufficient binding region:37-242	cub:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q6ZNB7	uniprotkb:Q5T9L3-1	intact:EBI-18509181|uniprotkb:A4D114|uniprotkb:A6NCH5|ensembl:ENSP00000341662	intact:EBI-22114623|ensembl:ENSP00000262348	psi-mi:alkmo_human(display_long)|uniprotkb:Transmembrane protein 195(gene name synonym)|uniprotkb:AGMO(gene name)|psi-mi:AGMO(display_short)|uniprotkb:TMEM195(gene name synonym)	psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Petko et al. (2019)	pubmed:31286866|imex:IM-27806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22118805|imex:IM-27806-67	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001004320.1|ensembl:ENSG00000187546(gene)|ensembl:ENST00000342526(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006643"(membrane lipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0050479"(glyceryl-ether monooxygenase activity)|interpro:IPR006694(Fatty acid hydroxylase)|reactome:R-HSA-75109|go:"GO:0046485"(ether lipid metabolic process)	ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent)	-	-	-	figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2019/10/08	2019/10/29	rogid:wy+ShH8vBzS15EJFthHNMOFqCs89606	rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606	rigid:uNWhGsCh7+9/u5RZ2QErmw9U4+s	false	nub:?-?	cub:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P51674	uniprotkb:Q5T9L3-1	intact:EBI-7187133|ensembl:ENSP00000280187|ensembl:ENSP00000377268|intact:UNK-5379643|uniprotkb:Q92602|uniprotkb:E9PHI5|uniprotkb:B7Z642	intact:EBI-22114623|ensembl:ENSP00000262348	psi-mi:gpm6a_human(display_long)|uniprotkb:GPM6A(gene name)|psi-mi:GPM6A(display_short)|uniprotkb:M6A(gene name synonym)	psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Petko et al. (2019)	pubmed:31286866|imex:IM-27806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22118815|imex:IM-27806-69	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000150625(gene)|ensembl:ENST00000280187(transcript)|ensembl:ENST00000393658(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003407"(neural retina development)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007416"(synapse assembly)|go:"GO:0009617"(response to bacterium)|go:"GO:0030175"(filopodium)|go:"GO:0031175"(neuron projection development)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044295"(axonal growth cone)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR001614(Myelin proteolipid protein PLP)|interpro:IPR018237|refseq:NP_001248377.1|refseq:NP_963885.1|refseq:NP_005268.1|refseq:NP_963886.1	ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent)	-	comment:mint|comment:homomint	-	figure legend:fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2019/10/08	2019/10/29	rogid:6h/p/+l8WRhJ9HsGcbxleQuDtSo9606	rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606	rigid:rQ3SOnM0672s8E4H4+rVv8cUSUw	false	nub:?-?	cub:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96D31	uniprotkb:Q5T9L3-1	intact:EBI-2291476|uniprotkb:Q3MHV3|uniprotkb:Q6DHX2|uniprotkb:Q96BP7|uniprotkb:Q96K71|ensembl:ENSP00000482568	intact:EBI-22114623|ensembl:ENSP00000262348	psi-mi:crcm1_human(display_long)|uniprotkb:ORAI1(gene name)|psi-mi:ORAI1(display_short)|uniprotkb:CRACM1(gene name synonym)|uniprotkb:TMEM142A(gene name synonym)|uniprotkb:Protein orai-1(gene name synonym)|uniprotkb:Transmembrane protein 142A(gene name synonym)	psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Petko et al. (2019)	pubmed:31286866|imex:IM-27806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22118823|imex:IM-27806-71	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_116179.2|go:"GO:0070588"(calcium ion transmembrane transport)|interpro:IPR012446(Protein of unknown function DUF1650)|interpro:IPR038350|rcsb pdb:2MAK|rcsb pdb:4EHQ|reactome:R-HSA-139853|reactome:R-HSA-5578775|reactome:R-HSA-983695|ensembl:ENSG00000276045(gene)|ensembl:ENST00000617316(transcript)|go:"GO:0002115"(store-operated calcium entry)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015279"(store-operated calcium channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0034704"(calcium channel complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045121"(membrane raft)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0061180"(mammary gland epithelium development)|go:"GO:0070509"(calcium ion import)|dip:DIP-46289N	ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent)	-	-	-	figure legend:fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2019/10/08	2019/10/29	rogid:VXcTrF/8sZA01XGUFZwvu75L7Kw9606	rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606	rigid:LaR5m8AJv0qw1Py2WTqJIAtrcCE	false	nub:?-?	cub:?-?|sufficient binding region:507-541	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15125	uniprotkb:Q5T9L3-2	intact:EBI-3915253|uniprotkb:Q6IBI9|uniprotkb:Q6FGL3|ensembl:ENSP00000417052	intact:EBI-21508346|ensembl:ENSP00000346829	psi-mi:ebp_human(display_long)|uniprotkb:EBP(gene name)|psi-mi:EBP(display_short)|uniprotkb:Cholestenol Delta-isomerase(gene name synonym)|uniprotkb:"Delta(8)-Delta(7) sterol isomerase"(gene name synonym)|uniprotkb:Emopamil-binding protein(gene name synonym)	psi-mi:q5t9l3-2(display_long)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Petko et al. (2019)	pubmed:31286866|imex:IM-27806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25497253|imex:IM-27806-76	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006570.1|ensembl:ENSG00000147155(gene)|ensembl:ENST00000495186(transcript)|go:"GO:0000247"(C-8 sterol isomerase activity)|go:"GO:0001501"(skeletal system development)|go:"GO:0004769"(steroid delta-isomerase activity)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033489"(cholesterol biosynthetic process via desmosterol)|go:"GO:0033490"(cholesterol biosynthetic process via lathosterol)|go:"GO:0042802"(identical protein binding)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0047750"(cholestenol delta-isomerase activity)|interpro:IPR007905(Emopamil-binding)|interpro:IPR033118|rcsb pdb:6OHT|rcsb pdb:6OHU|reactome:R-HSA-6807047|reactome:R-HSA-6807062	ensembl:ENSG00000116729(gene)|ensembl:ENST00000354777(transcript)|intact:EBI-2868748(isoform-parent)	-	-	-	figure legend:Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2019/10/08	2020/04/01	rogid:7XfeeD/twqYll0Hv4YuJUbmAVJ09606	rogid:suSstC7Z1iuclhX7sh47FceaErg9606	rigid:e/kV26Gl9DRgtXDvqvPT4fahbZk	false	nub:?-?	cub:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P55087	uniprotkb:Q5T9L3-2	intact:EBI-10104898|uniprotkb:P78564|ensembl:ENSP00000372654|ensembl:ENSP00000500720	intact:EBI-21508346|ensembl:ENSP00000346829	psi-mi:aqp4_human(display_long)|uniprotkb:AQP4(gene name)|psi-mi:AQP4(display_short)|uniprotkb:Mercurial-insensitive water channel(gene name synonym)|uniprotkb:WCH4(gene name synonym)	psi-mi:q5t9l3-2(display_long)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Petko et al. (2019)	pubmed:31286866|imex:IM-27806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22118600|imex:IM-27806-45	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001641.1|refseq:NP_004019.1|ensembl:ENSG00000171885(gene)|ensembl:ENST00000383168(transcript)|ensembl:ENST00000672188(transcript)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006833"(water transport)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009992"(cellular water homeostasis)|go:"GO:0010008"(endosome membrane)|go:"GO:0015250"(water channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030104"(water homeostasis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0050891"(multicellular organismal water homeostasis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090660"(cerebrospinal fluid circulation)|go:"GO:0097450"(astrocyte end-foot)|interpro:IPR000425(Major intrinsic protein)|interpro:IPR022357|interpro:IPR023271|interpro:IPR034294|rcsb pdb:3GD8|reactome:R-HSA-432040|reactome:R-HSA-432047|dip:DIP-48842N	ensembl:ENSG00000116729(gene)|ensembl:ENST00000354777(transcript)|intact:EBI-2868748(isoform-parent)	-	-	-	figure legend:Text|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2019/10/08	2019/10/29	rogid:emloJNSTB0zSwtP91cSKBBr4PA89606	rogid:suSstC7Z1iuclhX7sh47FceaErg9606	rigid:dsLMD/br6rFGiC3KNaj0g0PiM8g	false	nub:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NPA0	uniprotkb:Q5T9L3-2	intact:EBI-6309137|ensembl:ENSP00000256545|uniprotkb:B2RC00|uniprotkb:Q96ED5	intact:EBI-21508346|ensembl:ENSP00000346829	psi-mi:emc7_human(display_long)|uniprotkb:EMC7(gene name)|psi-mi:EMC7(display_short)|uniprotkb:C11orf3(gene name synonym)|uniprotkb:C15orf24(gene name synonym)|uniprotkb:HT022(orf name)|uniprotkb:UNQ905/PRO1926(orf name)	psi-mi:q5t9l3-2(display_long)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Petko et al. (2019)	pubmed:31286866|imex:IM-27806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22118679|imex:IM-27806-31	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000134153(gene)|ensembl:ENST00000256545(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR019008|interpro:IPR039163|rcsb pdb:1B0G|rcsb pdb:1LP9|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2UWE|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|refseq:NP_064539.1	ensembl:ENSG00000116729(gene)|ensembl:ENST00000354777(transcript)|intact:EBI-2868748(isoform-parent)	-	-	-	figure legend:Text|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2019/10/08	2019/10/29	rogid:XBg97fKNpvbssNf6YFewsWDmiBE9606	rogid:suSstC7Z1iuclhX7sh47FceaErg9606	rigid:IM4cLBsHU+BXySXMPC4fQfVitcE	false	nub:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51674	uniprotkb:Q5T9L3-2	intact:EBI-7187133|ensembl:ENSP00000280187|ensembl:ENSP00000377268|intact:UNK-5379643|uniprotkb:Q92602|uniprotkb:E9PHI5|uniprotkb:B7Z642	intact:EBI-21508346|ensembl:ENSP00000346829	psi-mi:gpm6a_human(display_long)|uniprotkb:GPM6A(gene name)|psi-mi:GPM6A(display_short)|uniprotkb:M6A(gene name synonym)	psi-mi:q5t9l3-2(display_long)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Petko et al. (2019)	pubmed:31286866|imex:IM-27806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22118688|imex:IM-27806-47	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000150625(gene)|ensembl:ENST00000280187(transcript)|ensembl:ENST00000393658(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003407"(neural retina development)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007416"(synapse assembly)|go:"GO:0009617"(response to bacterium)|go:"GO:0030175"(filopodium)|go:"GO:0031175"(neuron projection development)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044295"(axonal growth cone)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR001614(Myelin proteolipid protein PLP)|interpro:IPR018237|refseq:NP_001248377.1|refseq:NP_963885.1|refseq:NP_005268.1|refseq:NP_963886.1	ensembl:ENSG00000116729(gene)|ensembl:ENST00000354777(transcript)|intact:EBI-2868748(isoform-parent)	-	comment:mint|comment:homomint	-	figure legend:Text|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2019/10/08	2019/10/29	rogid:6h/p/+l8WRhJ9HsGcbxleQuDtSo9606	rogid:suSstC7Z1iuclhX7sh47FceaErg9606	rigid:FRkywS9tuRji0uVWiVzJJmUgvOU	false	nub:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6ZNB7	uniprotkb:Q5T9L3-2	intact:EBI-18509181|uniprotkb:A4D114|uniprotkb:A6NCH5|ensembl:ENSP00000341662	intact:EBI-21508346|ensembl:ENSP00000346829	psi-mi:alkmo_human(display_long)|uniprotkb:Transmembrane protein 195(gene name synonym)|uniprotkb:AGMO(gene name)|psi-mi:AGMO(display_short)|uniprotkb:TMEM195(gene name synonym)	psi-mi:q5t9l3-2(display_long)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Petko et al. (2019)	pubmed:31286866|imex:IM-27806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22118696|imex:IM-27806-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001004320.1|ensembl:ENSG00000187546(gene)|ensembl:ENST00000342526(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006643"(membrane lipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0050479"(glyceryl-ether monooxygenase activity)|interpro:IPR006694(Fatty acid hydroxylase)|reactome:R-HSA-75109|go:"GO:0046485"(ether lipid metabolic process)	ensembl:ENSG00000116729(gene)|ensembl:ENST00000354777(transcript)|intact:EBI-2868748(isoform-parent)	-	-	-	figure legend:Text|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2019/10/08	2019/10/29	rogid:wy+ShH8vBzS15EJFthHNMOFqCs89606	rogid:suSstC7Z1iuclhX7sh47FceaErg9606	rigid:WUgkpG4YK8K+hgGgG5fYa8XJyrw	false	nub:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96D31	uniprotkb:Q5T9L3-2	intact:EBI-2291476|uniprotkb:Q3MHV3|uniprotkb:Q6DHX2|uniprotkb:Q96BP7|uniprotkb:Q96K71|ensembl:ENSP00000482568	intact:EBI-21508346|ensembl:ENSP00000346829	psi-mi:crcm1_human(display_long)|uniprotkb:ORAI1(gene name)|psi-mi:ORAI1(display_short)|uniprotkb:CRACM1(gene name synonym)|uniprotkb:TMEM142A(gene name synonym)|uniprotkb:Protein orai-1(gene name synonym)|uniprotkb:Transmembrane protein 142A(gene name synonym)	psi-mi:q5t9l3-2(display_long)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Petko et al. (2019)	pubmed:31286866|imex:IM-27806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22118704|imex:IM-27806-33	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_116179.2|go:"GO:0070588"(calcium ion transmembrane transport)|interpro:IPR012446(Protein of unknown function DUF1650)|interpro:IPR038350|rcsb pdb:2MAK|rcsb pdb:4EHQ|reactome:R-HSA-139853|reactome:R-HSA-5578775|reactome:R-HSA-983695|ensembl:ENSG00000276045(gene)|ensembl:ENST00000617316(transcript)|go:"GO:0002115"(store-operated calcium entry)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015279"(store-operated calcium channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0034704"(calcium channel complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045121"(membrane raft)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0061180"(mammary gland epithelium development)|go:"GO:0070509"(calcium ion import)|dip:DIP-46289N	ensembl:ENSG00000116729(gene)|ensembl:ENST00000354777(transcript)|intact:EBI-2868748(isoform-parent)	-	-	-	figure legend:Text|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2019/10/08	2019/10/29	rogid:VXcTrF/8sZA01XGUFZwvu75L7Kw9606	rogid:suSstC7Z1iuclhX7sh47FceaErg9606	rigid:Jr/yueXRyxvImL4PegCDBBcKbnc	false	nub:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14316	uniprotkb:Q5T9L3-2	intact:EBI-2866589|uniprotkb:Q96B99|intact:EBI-3918980|uniprotkb:D6RCK5|uniprotkb:H0Y8S3|uniprotkb:Q6IAS7|ensembl:ENSP00000377218	intact:EBI-21508346|ensembl:ENSP00000346829	psi-mi:irf2_human(display_long)|uniprotkb:IRF2(gene name)|psi-mi:IRF2(display_short)	psi-mi:q5t9l3-2(display_long)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Petko et al. (2019)	pubmed:31286866|imex:IM-27806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22118712|imex:IM-27806-63	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002190.2|ensembl:ENSG00000168310(gene)|ensembl:ENST00000393593(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031218|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231	ensembl:ENSG00000116729(gene)|ensembl:ENST00000354777(transcript)|intact:EBI-2868748(isoform-parent)	-	-	-	figure legend:Text|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2019/10/08	2019/10/29	rogid:zERch/mQ12S0euBLQp/dEtKzl+49606	rogid:suSstC7Z1iuclhX7sh47FceaErg9606	rigid:qr5tVIz70DtXMR5WFKCCIEeT7pY	false	nub:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H4P4	uniprotkb:Q5T9L3-2	intact:EBI-2130266|uniprotkb:B2RBT8|uniprotkb:O75598|intact:EBI-2563208|intact:EBI-11576203|uniprotkb:A6NFW0|ensembl:ENSP00000342755|ensembl:ENSP00000447303|ensembl:ENSP00000484671	intact:EBI-21508346|ensembl:ENSP00000346829	psi-mi:rnf41_human(display_long)|uniprotkb:RNF41(gene name)|psi-mi:RNF41(display_short)|uniprotkb:FLRF(gene name synonym)|uniprotkb:NRDP1(gene name synonym)|uniprotkb:RING finger protein 41(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase NRDP1(gene name synonym)|uniprotkb:SBBI03(orf name)	psi-mi:q5t9l3-2(display_long)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Petko et al. (2019)	pubmed:31286866|imex:IM-27806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22118732|imex:IM-27806-65	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011536036.1|refseq:XP_011536037.1|refseq:NP_001229755.1|refseq:NP_005776.1|refseq:NP_919340.1|refseq:NP_919339.1|refseq:XP_005268618.1|ensembl:ENSG00000181852(gene)|ensembl:ENST00000345093(transcript)|ensembl:ENST00000552656(transcript)|ensembl:ENST00000615206(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013010(Zinc finger, SIAH-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015036(USP8 interacting)|interpro:IPR017907|interpro:IPR037255|rcsb pdb:2FZP|rcsb pdb:2GWF|reactome:R-HSA-1358803|reactome:R-HSA-983168	ensembl:ENSG00000116729(gene)|ensembl:ENST00000354777(transcript)|intact:EBI-2868748(isoform-parent)	-	-	-	figure legend:Text|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2019/10/08	2019/10/29	rogid:jthVZwxUECSdqeJ2jZQ5UL28kDY9606	rogid:suSstC7Z1iuclhX7sh47FceaErg9606	rigid:1Rkp+AB21eJN2+JkC6X1sJmR9Vg	false	nub:?-?	cub:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51674	uniprotkb:Q5T9L3-1	intact:EBI-7187133|ensembl:ENSP00000280187|ensembl:ENSP00000377268|intact:UNK-5379643|uniprotkb:Q92602|uniprotkb:E9PHI5|uniprotkb:B7Z642	intact:EBI-22114623|ensembl:ENSP00000262348	psi-mi:gpm6a_human(display_long)|uniprotkb:GPM6A(gene name)|psi-mi:GPM6A(display_short)|uniprotkb:M6A(gene name synonym)	psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:"MI:0096"(pull down)	Petko et al. (2019)	pubmed:31286866|imex:IM-27806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22118851|imex:IM-27806-53	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000150625(gene)|ensembl:ENST00000280187(transcript)|ensembl:ENST00000393658(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003407"(neural retina development)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007416"(synapse assembly)|go:"GO:0009617"(response to bacterium)|go:"GO:0030175"(filopodium)|go:"GO:0031175"(neuron projection development)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044295"(axonal growth cone)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR001614(Myelin proteolipid protein PLP)|interpro:IPR018237|refseq:NP_001248377.1|refseq:NP_963885.1|refseq:NP_005268.1|refseq:NP_963886.1	ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent)	-	comment:mint|comment:homomint	-	figure legend:fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/10/08	2019/10/29	rogid:6h/p/+l8WRhJ9HsGcbxleQuDtSo9606	rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606	rigid:rQ3SOnM0672s8E4H4+rVv8cUSUw	false	s tag:?-?|sufficient binding region:235..235-278..278	sufficient binding region:254-268|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P29274	uniprotkb:Q5T9L3-1	intact:EBI-2902702|ensembl:ENSP00000336630|ensembl:ENSP00000480012|ensembl:ENSP00000481552|ensembl:ENSP00000483102|uniprotkb:B2R7E0	intact:EBI-22114623|ensembl:ENSP00000262348	psi-mi:aa2ar_human(display_long)|uniprotkb:ADORA2A(gene name)|psi-mi:ADORA2A(display_short)|uniprotkb:ADORA2(gene name synonym)	psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:"MI:0096"(pull down)	Petko et al. (2019)	pubmed:31286866|imex:IM-27806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22118870|imex:IM-27806-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000128271(gene)|ensembl:ENST00000337539(transcript)|ensembl:ENST00000610595(transcript)|ensembl:ENST00000611543(transcript)|ensembl:ENST00000618076(transcript)|go:"GO:0001609"(G protein-coupled adenosine receptor activity)|go:"GO:0001963"(synaptic transmission, dopaminergic)|go:"GO:0001975"(response to amphetamine)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006909"(phagocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007417"(central nervous system development)|go:"GO:0007596"(blood coagulation)|go:"GO:0007600"(sensory perception)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0012505"(endomembrane system)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014057"(positive regulation of acetylcholine secretion, neurotransmission)|go:"GO:0014061"(regulation of norepinephrine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0030673"(axolemma)|go:"GO:0031000"(response to caffeine)|go:"GO:0031802"(type 5 metabotropic glutamate receptor binding)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035810"(positive regulation of urine volume)|go:"GO:0035815"(positive regulation of renal sodium excretion)|go:"GO:0040013"(negative regulation of locomotion)|go:"GO:0042311"(vasodilation)|go:"GO:0042493"|go:"GO:0042755"(eating behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045938"(positive regulation of circadian sleep/wake cycle, sleep)|go:"GO:0046636"(negative regulation of alpha-beta T cell activation)|go:"GO:0048143"(astrocyte activation)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0051899"(membrane depolarization)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060080"(inhibitory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001513(Adenosine A2A receptor)|interpro:IPR001634(Adenosine receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P29274|rcsb pdb:1MMH|rcsb pdb:1UPE|rcsb pdb:2YDO|rcsb pdb:2YDV|rcsb pdb:3EML|rcsb pdb:3PWH|rcsb pdb:3QAK|rcsb pdb:3REY|rcsb pdb:3RFM|rcsb pdb:3UZA|rcsb pdb:3UZC|rcsb pdb:3VG9|rcsb pdb:3VGA|rcsb pdb:4UG2|rcsb pdb:4UHR|rcsb pdb:5G53|rcsb pdb:5IU4|rcsb pdb:5IU7|rcsb pdb:5IU8|rcsb pdb:5IUA|rcsb pdb:5IUB|rcsb pdb:5JTB|rcsb pdb:5K2A|rcsb pdb:5K2B|rcsb pdb:5K2C|rcsb pdb:5K2D|rcsb pdb:5MZJ|rcsb pdb:5MZP|rcsb pdb:5N2R|rcsb pdb:5NLX|rcsb pdb:5NM2|rcsb pdb:5NM4|rcsb pdb:5OLG|rcsb pdb:5OLH|rcsb pdb:5OLO|rcsb pdb:5OLV|rcsb pdb:5OLZ|rcsb pdb:5OM1|rcsb pdb:5OM4|rcsb pdb:4EIY|rcsb pdb:5UIG|rcsb pdb:5UVI|rcsb pdb:5WF5|rcsb pdb:5WF6|rcsb pdb:6AQF|rcsb pdb:6GDG|rcsb pdb:6GT3|rcsb pdb:6JZH|rcsb pdb:6LPJ|rcsb pdb:6LPK|rcsb pdb:6LPL|rcsb pdb:6MH8|rcsb pdb:6PS7|rcsb pdb:6S0L|rcsb pdb:6S0Q|rcsb pdb:6WQA|rcsb pdb:6ZDR|rcsb pdb:6ZDV|rcsb pdb:7ARO|reactome:R-HSA-187024|reactome:R-HSA-417973|reactome:R-HSA-418555|reactome:R-HSA-5683826|reactome:R-HSA-9660821|rcsb pdb:5VRA|refseq:NP_000666.2|refseq:NP_001265426.1|refseq:NP_001265427.1|refseq:NP_001265428.1|refseq:NP_001265429.1	ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent)	-	-	-	figure legend:fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/10/08	2020/04/02	rogid:3LgXP8J8wfsw4G5kVvY/8vVp4DA9606	rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606	rigid:V1e2yMlRQBE3ZLZVXjGSh69GcGU	false	sufficient binding region:291-412|glutathione s tranferase tag:n-n	sufficient binding region:493-541|s tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q5T9L3-2	uniprotkb:P29274	intact:EBI-21508346|ensembl:ENSP00000346829	intact:EBI-2902702|ensembl:ENSP00000336630|ensembl:ENSP00000480012|ensembl:ENSP00000481552|ensembl:ENSP00000483102|uniprotkb:B2R7E0	psi-mi:q5t9l3-2(display_long)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:aa2ar_human(display_long)|uniprotkb:ADORA2A(gene name)|psi-mi:ADORA2A(display_short)|uniprotkb:ADORA2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Petko et al. (2019)	pubmed:31286866|imex:IM-27806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22118883|imex:IM-27806-73	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000116729(gene)|ensembl:ENST00000354777(transcript)|intact:EBI-2868748(isoform-parent)	ensembl:ENSG00000128271(gene)|ensembl:ENST00000337539(transcript)|ensembl:ENST00000610595(transcript)|ensembl:ENST00000611543(transcript)|ensembl:ENST00000618076(transcript)|go:"GO:0001609"(G protein-coupled adenosine receptor activity)|go:"GO:0001963"(synaptic transmission, dopaminergic)|go:"GO:0001975"(response to amphetamine)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006909"(phagocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007417"(central nervous system development)|go:"GO:0007596"(blood coagulation)|go:"GO:0007600"(sensory perception)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0012505"(endomembrane system)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014057"(positive regulation of acetylcholine secretion, neurotransmission)|go:"GO:0014061"(regulation of norepinephrine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0030673"(axolemma)|go:"GO:0031000"(response to caffeine)|go:"GO:0031802"(type 5 metabotropic glutamate receptor binding)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035810"(positive regulation of urine volume)|go:"GO:0035815"(positive regulation of renal sodium excretion)|go:"GO:0040013"(negative regulation of locomotion)|go:"GO:0042311"(vasodilation)|go:"GO:0042493"|go:"GO:0042755"(eating behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045938"(positive regulation of circadian sleep/wake cycle, sleep)|go:"GO:0046636"(negative regulation of alpha-beta T cell activation)|go:"GO:0048143"(astrocyte activation)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0051899"(membrane depolarization)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060080"(inhibitory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001513(Adenosine A2A receptor)|interpro:IPR001634(Adenosine receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P29274|rcsb pdb:1MMH|rcsb pdb:1UPE|rcsb pdb:2YDO|rcsb pdb:2YDV|rcsb pdb:3EML|rcsb pdb:3PWH|rcsb pdb:3QAK|rcsb pdb:3REY|rcsb pdb:3RFM|rcsb pdb:3UZA|rcsb pdb:3UZC|rcsb pdb:3VG9|rcsb pdb:3VGA|rcsb pdb:4UG2|rcsb pdb:4UHR|rcsb pdb:5G53|rcsb pdb:5IU4|rcsb pdb:5IU7|rcsb pdb:5IU8|rcsb pdb:5IUA|rcsb pdb:5IUB|rcsb pdb:5JTB|rcsb pdb:5K2A|rcsb pdb:5K2B|rcsb pdb:5K2C|rcsb pdb:5K2D|rcsb pdb:5MZJ|rcsb pdb:5MZP|rcsb pdb:5N2R|rcsb pdb:5NLX|rcsb pdb:5NM2|rcsb pdb:5NM4|rcsb pdb:5OLG|rcsb pdb:5OLH|rcsb pdb:5OLO|rcsb pdb:5OLV|rcsb pdb:5OLZ|rcsb pdb:5OM1|rcsb pdb:5OM4|rcsb pdb:4EIY|rcsb pdb:5UIG|rcsb pdb:5UVI|rcsb pdb:5WF5|rcsb pdb:5WF6|rcsb pdb:6AQF|rcsb pdb:6GDG|rcsb pdb:6GT3|rcsb pdb:6JZH|rcsb pdb:6LPJ|rcsb pdb:6LPK|rcsb pdb:6LPL|rcsb pdb:6MH8|rcsb pdb:6PS7|rcsb pdb:6S0L|rcsb pdb:6S0Q|rcsb pdb:6WQA|rcsb pdb:6ZDR|rcsb pdb:6ZDV|rcsb pdb:7ARO|reactome:R-HSA-187024|reactome:R-HSA-417973|reactome:R-HSA-418555|reactome:R-HSA-5683826|reactome:R-HSA-9660821|rcsb pdb:5VRA|refseq:NP_000666.2|refseq:NP_001265426.1|refseq:NP_001265427.1|refseq:NP_001265428.1|refseq:NP_001265429.1	-	-	-	figure legend:fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/10/08	2019/10/29	rogid:suSstC7Z1iuclhX7sh47FceaErg9606	rogid:3LgXP8J8wfsw4G5kVvY/8vVp4DA9606	rigid:liMtwcqz8+xmjwvE+UnVGNsOses	false	sufficient binding region:505-543|s tag:?-?	sufficient binding region:291-412|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P35372	uniprotkb:Q5T9L3-1	intact:EBI-2624570|uniprotkb:B0FXJ1|uniprotkb:B8Q1L8|uniprotkb:B8Q1L9|uniprotkb:Q6UPP1|uniprotkb:Q86V80|uniprotkb:G8XRH8|uniprotkb:B2R9S7|uniprotkb:B8Q1L7|uniprotkb:Q12930|uniprotkb:Q4VWM1|uniprotkb:Q4VWM2|uniprotkb:Q4VWM3|uniprotkb:Q4VWM4|uniprotkb:Q4VWM6|uniprotkb:Q4VWX6|uniprotkb:Q5TDA1|uniprotkb:Q6UQ80|uniprotkb:Q7Z2D8|uniprotkb:Q8IWW3|uniprotkb:Q8IWW4|uniprotkb:Q9UCZ4|uniprotkb:Q9UN57|uniprotkb:G8XRH6|ensembl:ENSP00000328264|uniprotkb:E7EWZ3	intact:EBI-22114623|ensembl:ENSP00000262348	psi-mi:oprm_human(display_long)|uniprotkb:OPRM1(gene name)|psi-mi:OPRM1(display_short)|uniprotkb:MOR1(gene name synonym)|uniprotkb:Mu opioid receptor(gene name synonym)|uniprotkb:Mu opiate receptor(gene name synonym)	psi-mi:q5t9l3-1(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:"MI:0096"(pull down)	Petko et al. (2019)	pubmed:31286866|imex:IM-27806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22118896|imex:IM-27806-55	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001272453.1|refseq:NP_001272455.1|refseq:NP_001272456.1|refseq:NP_001272457.1|refseq:NP_001138752.1|refseq:NP_001138753.1|refseq:NP_001272452.1|refseq:NP_000905.3|refseq:NP_001008503.2|refseq:NP_001008504.2|refseq:NP_001008505.2|refseq:NP_001138751.1|refseq:NP_001138754.1|refseq:NP_001138755.1|refseq:NP_001138756.1|refseq:NP_001138757.1|refseq:NP_001138758.1|refseq:NP_001138759.1|refseq:XP_016866395.1|ensembl:ENSG00000112038(gene)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0007600"(sensory perception)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009314"(response to radiation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031005"(filamin binding)|go:"GO:0031635"(adenylate cyclase-inhibiting opioid receptor signaling pathway)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032094"(response to food)|go:"GO:0032100"(positive regulation of appetite)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032590"(dendrite membrane)|ensembl:ENST00000330432(transcript)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0038003"(G protein-coupled opioid receptor signaling pathway)|go:"GO:0038047"(morphine receptor activity)|go:"GO:0042060"(wound healing)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0002438"(acute inflammatory response to antigenic stimulus)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004979"(beta-endorphin receptor activity)|go:"GO:0042755"(eating behavior)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0043950"(positive regulation of cAMP-mediated signaling)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0044849"(estrous cycle)|go:"GO:0005768"(endosome)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0061358"(negative regulation of Wnt protein secretion)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070848"(response to growth factor)|go:"GO:0080135"(regulation of cellular response to stress)|go:"GO:0097444"(spine apparatus)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:2000310"(regulation of NMDA receptor activity)|interpro:IPR000105(Mu opioid receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001418(Opioid receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P35372|reactome:R-HSA-111885|reactome:R-HSA-202040|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007197"(adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway)|reactome:R-HSA-418594|reactome:R-HSA-6785807|reactome:R-HSA-9022699|reactome:R-HSA-375276	ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|intact:EBI-2868748(isoform-parent)	intact:EBI-22118916(see-also)	-	-	figure legend:fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/10/08	2020/04/02	rogid:pfkhVhvpn9gSXiBRs1OBXJBCI3s9606	rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606	rigid:L0/aG/OpMFYZtU+dhQVG/GuA9eQ	false	sufficient binding region:166-187|glutathione s tranferase tag:n-n	sufficient binding region:493-541|s tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q5T9L3-2	uniprotkb:Q5T9L3-2	intact:EBI-21508346|ensembl:ENSP00000346829	intact:EBI-21508346|ensembl:ENSP00000346829	psi-mi:q5t9l3-2(display_long)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:q5t9l3-2(display_long)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:"MI:0096"(pull down)	Petko et al. (2019)	pubmed:31286866|imex:IM-27806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22118931|imex:IM-27806-75	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000116729(gene)|ensembl:ENST00000354777(transcript)|intact:EBI-2868748(isoform-parent)	ensembl:ENSG00000116729(gene)|ensembl:ENST00000354777(transcript)|intact:EBI-2868748(isoform-parent)	intact:EBI-22118943(see-also)	-	-	figure legend:fig. 5B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/10/08	2019/10/29	rogid:suSstC7Z1iuclhX7sh47FceaErg9606	rogid:suSstC7Z1iuclhX7sh47FceaErg9606	rigid:RGidilBBHWY1lL7aup7euYsJq7g	false	sufficient binding region:505-543|glutathione s tranferase tag:n-n	sufficient binding region:505-543|s tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)