#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:A0A126GV13 uniprotkb:A0A126GV13 intact:EBI-21913848|ensemblmetazoa:FBpp0401488 intact:EBI-21913848|ensemblmetazoa:FBpp0401488 psi-mi:a0a126gv13_drome(display_long)|uniprotkb:spas(gene name)|psi-mi:spas(display_short)|uniprotkb:D-spastin(gene name synonym)|uniprotkb:Dmel\CG5977(gene name synonym)|uniprotkb:Dspastin(gene name synonym)|uniprotkb:Spas(gene name synonym)|uniprotkb:Spastin(gene name synonym)|uniprotkb:CG5977(orf name)|uniprotkb:Dmel_CG5977(orf name) psi-mi:a0a126gv13_drome(display_long)|uniprotkb:spas(gene name)|psi-mi:spas(display_short)|uniprotkb:D-spastin(gene name synonym)|uniprotkb:Dmel\CG5977(gene name synonym)|uniprotkb:Dspastin(gene name synonym)|uniprotkb:Spas(gene name synonym)|uniprotkb:Spastin(gene name synonym)|uniprotkb:CG5977(orf name)|uniprotkb:Dmel_CG5977(orf name) psi-mi:"MI:0410"(3D electron microscopy) Sandate et al. (2019) pubmed:31285604|imex:IM-28072 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-21913890|wwpdb:6P07|emdb:EMD-20226|imex:IM-28072-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001303437.1|flybase:FBgn0039141|ensemblmetazoa:FBgn0039141(gene)|ensemblmetazoa:FBtr0445311(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0005524"(ATP binding)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007399"(nervous system development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0031117"(positive regulation of microtubule depolymerization)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0051301"(cell division)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR017179(Spastin)|interpro:IPR027417|interpro:IPR036181|interpro:IPR041569 refseq:NP_001303437.1|flybase:FBgn0039141|ensemblmetazoa:FBgn0039141(gene)|ensemblmetazoa:FBtr0445311(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0005524"(ATP binding)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007399"(nervous system development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0031117"(positive regulation of microtubule depolymerization)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0051301"(cell division)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR017179(Spastin)|interpro:IPR027417|interpro:IPR036181|interpro:IPR041569 - - - figure legend:Fig 1, Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2019/07/11 2019/07/11 rogid:oUTbn3UvHiHJBtxk9Byb5tbS9+o7227 rogid:oUTbn3UvHiHJBtxk9Byb5tbS9+o7227 rigid:89clgBB4WwohF6rUfsRUfR/idmM false mutation:314-314 mutation:314-314 6 0 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:A0A126GV13 uniprotkb:A0A126GV13 intact:EBI-21913848|ensemblmetazoa:FBpp0401488 intact:EBI-21913848|ensemblmetazoa:FBpp0401488 psi-mi:a0a126gv13_drome(display_long)|uniprotkb:spas(gene name)|psi-mi:spas(display_short)|uniprotkb:D-spastin(gene name synonym)|uniprotkb:Dmel\CG5977(gene name synonym)|uniprotkb:Dspastin(gene name synonym)|uniprotkb:Spas(gene name synonym)|uniprotkb:Spastin(gene name synonym)|uniprotkb:CG5977(orf name)|uniprotkb:Dmel_CG5977(orf name) psi-mi:a0a126gv13_drome(display_long)|uniprotkb:spas(gene name)|psi-mi:spas(display_short)|uniprotkb:D-spastin(gene name synonym)|uniprotkb:Dmel\CG5977(gene name synonym)|uniprotkb:Dspastin(gene name synonym)|uniprotkb:Spas(gene name synonym)|uniprotkb:Spastin(gene name synonym)|uniprotkb:CG5977(orf name)|uniprotkb:Dmel_CG5977(orf name) psi-mi:"MI:0028"(cosedimentation in solution) Sandate et al. (2019) pubmed:31285604|imex:IM-28072 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-21913905|imex:IM-28072-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001303437.1|flybase:FBgn0039141|ensemblmetazoa:FBgn0039141(gene)|ensemblmetazoa:FBtr0445311(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0005524"(ATP binding)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007399"(nervous system development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0031117"(positive regulation of microtubule depolymerization)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0051301"(cell division)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR017179(Spastin)|interpro:IPR027417|interpro:IPR036181|interpro:IPR041569 refseq:NP_001303437.1|flybase:FBgn0039141|ensemblmetazoa:FBgn0039141(gene)|ensemblmetazoa:FBtr0445311(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0005524"(ATP binding)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007399"(nervous system development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0031117"(positive regulation of microtubule depolymerization)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0051301"(cell division)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR017179(Spastin)|interpro:IPR027417|interpro:IPR036181|interpro:IPR041569 - - - figure legend:Sup Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2019/07/11 2019/07/11 rogid:oUTbn3UvHiHJBtxk9Byb5tbS9+o7227 rogid:oUTbn3UvHiHJBtxk9Byb5tbS9+o7227 rigid:89clgBB4WwohF6rUfsRUfR/idmM false mutation:314-314 mutation:314-314 6 0 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)