#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B chebi:"CHEBI:145416" uniprotkb:Q696P8 intact:EBI-22224505 intact:EBI-22186725 psi-mi:"methyl 9-o-acetyl-5-(acetylamino)-3,5-dideoxy-d-glycero-alpha-d-galacto-non-2-ulopyranosidonic acid"(display_short)|psi-mi:"CHEBI:145416"(display_long) psi-mi:q696p8_cvhoc(display_long)|uniprotkb:E2(gene name synonym)|uniprotkb:Peplomer protein(gene name synonym)|uniprotkb:S(gene name)|psi-mi:S(display_short) psi-mi:"MI:0410"(3D electron microscopy) Tortorici et al. (2019) pubmed:31160783|imex:IM-27499 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:31631(HCoV-OC43)|taxid:31631(Human coronavirus OC43) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-22186748|wwpdb:6nzk|imex:IM-27499-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0044173"(host cell endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046813"(receptor-mediated virion attachment to host cell)|go:"GO:0055036"(virion membrane)|go:"GO:0075509"(endocytosis involved in viral entry into host cell)|interpro:IPR044873|interpro:IPR044874|interpro:IPR043607|interpro:IPR043614|rcsb pdb:6NZK|rcsb pdb:6OHW|interpro:IPR042578|interpro:IPR002552(Coronavirus S2 glycoprotein)|interpro:IPR032500|interpro:IPR018548|interpro:IPR036326|interpro:IPR043002|interpro:IPR043473|interpro:IPR044339|interpro:IPR044372 emdb:EMD-0557(see-also) - - figure legend:Fig. 1, Table 1, Supplementary Figure 1|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2019/11/08 2019/11/19 - rogid:xkuZabRCaKGTLE5HL8623kRatTE31631 - false - sufficient binding region:15-1263|strep tag:c-c|mutation:754-754,755-755,757-757 3 3 psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:2287"(identification by structure determination) uniprotkb:Q696P8 uniprotkb:Q696P8 intact:EBI-22186725 intact:EBI-22186725 psi-mi:q696p8_cvhoc(display_long)|uniprotkb:E2(gene name synonym)|uniprotkb:Peplomer protein(gene name synonym)|uniprotkb:S(gene name)|psi-mi:S(display_short) psi-mi:q696p8_cvhoc(display_long)|uniprotkb:E2(gene name synonym)|uniprotkb:Peplomer protein(gene name synonym)|uniprotkb:S(gene name)|psi-mi:S(display_short) psi-mi:"MI:0410"(3D electron microscopy) Tortorici et al. (2019) pubmed:31160783|imex:IM-27499 taxid:31631(HCoV-OC43)|taxid:31631(Human coronavirus OC43) taxid:31631(HCoV-OC43)|taxid:31631(Human coronavirus OC43) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-22224509|wwpdb:6ohw|imex:IM-27499-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0044173"(host cell endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046813"(receptor-mediated virion attachment to host cell)|go:"GO:0055036"(virion membrane)|go:"GO:0075509"(endocytosis involved in viral entry into host cell)|interpro:IPR044873|interpro:IPR044874|interpro:IPR043607|interpro:IPR043614|rcsb pdb:6NZK|rcsb pdb:6OHW|interpro:IPR042578|interpro:IPR002552(Coronavirus S2 glycoprotein)|interpro:IPR032500|interpro:IPR018548|interpro:IPR036326|interpro:IPR043002|interpro:IPR043473|interpro:IPR044339|interpro:IPR044372 go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0044173"(host cell endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046813"(receptor-mediated virion attachment to host cell)|go:"GO:0055036"(virion membrane)|go:"GO:0075509"(endocytosis involved in viral entry into host cell)|interpro:IPR044873|interpro:IPR044874|interpro:IPR043607|interpro:IPR043614|rcsb pdb:6NZK|rcsb pdb:6OHW|interpro:IPR042578|interpro:IPR002552(Coronavirus S2 glycoprotein)|interpro:IPR032500|interpro:IPR018548|interpro:IPR036326|interpro:IPR043002|interpro:IPR043473|interpro:IPR044339|interpro:IPR044372 emdb:EMD-20070(see-also) - - figure legend:Fig. 1, Table 1, Supplementary Figure 1i|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2019/11/08 2019/11/19 rogid:xkuZabRCaKGTLE5HL8623kRatTE31631 rogid:xkuZabRCaKGTLE5HL8623kRatTE31631 rigid:Mrgn8nFsRXtrtO4ISLHWocYGDKc false strep tag:c-c|sufficient binding region:15-1263|mutation:754-754,755-755,757-757 strep tag:c-c|sufficient binding region:15-1263|mutation:754-754,755-755,757-757 3 0 psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination)