#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O60353 uniprotkb:P47972 intact:EBI-8754490|uniprotkb:B4DRN0|uniprotkb:Q6N0A5|uniprotkb:Q6P9C3|uniprotkb:Q8WXR9|ensembl:ENSP00000351605|ensembl:ENSP00000429055 intact:EBI-3957229|ensembl:ENSP00000265634|uniprotkb:A4D267|uniprotkb:Q86XV7|uniprotkb:Q96G70 psi-mi:fzd6_human(display_long)|uniprotkb:FZD6(gene name)|psi-mi:FZD6(display_short) psi-mi:nptx2_human(display_long)|uniprotkb:NPTX2(gene name)|psi-mi:NPTX2(display_short)|uniprotkb:Neuronal pentraxin II(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xu et al. (2019) pubmed:30833544|imex:IM-27500 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-21257432|imex:IM-27500-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001304725.1|refseq:NP_001158087.1|refseq:NP_001158088.1|refseq:NP_003497.2|ensembl:ENSG00000164930(gene)|ensembl:ENST00000358755(transcript)|ensembl:ENST00000522566(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001942"(hair follicle development)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030168"(platelet activation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033278"(cell proliferation in midbrain)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0035880"(embryonic nail plate morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042813"(Wnt-activated receptor activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0048105"(establishment of body hair planar orientation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904693"(midbrain morphogenesis)|interpro:IPR000539(Frizzled protein)|interpro:IPR015526(Frizzled related)|interpro:IPR017981|interpro:IPR020067|interpro:IPR026543|interpro:IPR036790|interpro:IPR041770|reactome:R-HSA-373080|reactome:R-HSA-4086398|reactome:R-HSA-4086400|reactome:R-HSA-4641263|reactome:R-HSA-5340588|dip:DIP-59893N ensembl:ENSG00000106236(gene)|ensembl:ENST00000265634(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008306"(associative learning)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001759(Pentaxin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR030476|refseq:NP_002514.1 - - - figure legend:Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sw480)|taxid:9606(Human SW480 adenocarcinoma cell line) - 2019/03/13 2019/03/13 rogid:vBccj/vFYRExa+isZOvQLQXm4409606 rogid:Z/EPfPB0inTUQyHKIDh172ltpaw9606 rigid:T27w7at2mmyHQ1xw9U4meYe/lbk false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O60353 uniprotkb:P47972 intact:EBI-8754490|uniprotkb:B4DRN0|uniprotkb:Q6N0A5|uniprotkb:Q6P9C3|uniprotkb:Q8WXR9|ensembl:ENSP00000351605|ensembl:ENSP00000429055 intact:EBI-3957229|ensembl:ENSP00000265634|uniprotkb:A4D267|uniprotkb:Q86XV7|uniprotkb:Q96G70 psi-mi:fzd6_human(display_long)|uniprotkb:FZD6(gene name)|psi-mi:FZD6(display_short) psi-mi:nptx2_human(display_long)|uniprotkb:NPTX2(gene name)|psi-mi:NPTX2(display_short)|uniprotkb:Neuronal pentraxin II(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xu et al. (2019) pubmed:30833544|imex:IM-27500 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-21257436|imex:IM-27500-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001304725.1|refseq:NP_001158087.1|refseq:NP_001158088.1|refseq:NP_003497.2|ensembl:ENSG00000164930(gene)|ensembl:ENST00000358755(transcript)|ensembl:ENST00000522566(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001942"(hair follicle development)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030168"(platelet activation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033278"(cell proliferation in midbrain)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0035880"(embryonic nail plate morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042813"(Wnt-activated receptor activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0048105"(establishment of body hair planar orientation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904693"(midbrain morphogenesis)|interpro:IPR000539(Frizzled protein)|interpro:IPR015526(Frizzled related)|interpro:IPR017981|interpro:IPR020067|interpro:IPR026543|interpro:IPR036790|interpro:IPR041770|reactome:R-HSA-373080|reactome:R-HSA-4086398|reactome:R-HSA-4086400|reactome:R-HSA-4641263|reactome:R-HSA-5340588|dip:DIP-59893N ensembl:ENSG00000106236(gene)|ensembl:ENST00000265634(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008306"(associative learning)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001759(Pentaxin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR030476|refseq:NP_002514.1 - - - figure legend:Fig. 5D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sw480)|taxid:9606(Human SW480 adenocarcinoma cell line) - 2019/03/13 2019/03/13 rogid:vBccj/vFYRExa+isZOvQLQXm4409606 rogid:Z/EPfPB0inTUQyHKIDh172ltpaw9606 rigid:T27w7at2mmyHQ1xw9U4meYe/lbk false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O60353 uniprotkb:P47972 intact:EBI-8754490|uniprotkb:B4DRN0|uniprotkb:Q6N0A5|uniprotkb:Q6P9C3|uniprotkb:Q8WXR9|ensembl:ENSP00000351605|ensembl:ENSP00000429055 intact:EBI-3957229|ensembl:ENSP00000265634|uniprotkb:A4D267|uniprotkb:Q86XV7|uniprotkb:Q96G70 psi-mi:fzd6_human(display_long)|uniprotkb:FZD6(gene name)|psi-mi:FZD6(display_short) psi-mi:nptx2_human(display_long)|uniprotkb:NPTX2(gene name)|psi-mi:NPTX2(display_short)|uniprotkb:Neuronal pentraxin II(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xu et al. (2019) pubmed:30833544|imex:IM-27500 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-21257448|imex:IM-27500-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001304725.1|refseq:NP_001158087.1|refseq:NP_001158088.1|refseq:NP_003497.2|ensembl:ENSG00000164930(gene)|ensembl:ENST00000358755(transcript)|ensembl:ENST00000522566(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001942"(hair follicle development)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030168"(platelet activation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033278"(cell proliferation in midbrain)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0035880"(embryonic nail plate morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042813"(Wnt-activated receptor activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0048105"(establishment of body hair planar orientation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904693"(midbrain morphogenesis)|interpro:IPR000539(Frizzled protein)|interpro:IPR015526(Frizzled related)|interpro:IPR017981|interpro:IPR020067|interpro:IPR026543|interpro:IPR036790|interpro:IPR041770|reactome:R-HSA-373080|reactome:R-HSA-4086398|reactome:R-HSA-4086400|reactome:R-HSA-4641263|reactome:R-HSA-5340588|dip:DIP-59893N ensembl:ENSG00000106236(gene)|ensembl:ENST00000265634(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008306"(associative learning)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001759(Pentaxin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR030476|refseq:NP_002514.1 - - - figure legend:Fig. 5D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-lovo)|taxid:9606(Homo sapiens colon adenocarcinoma cell line lovo) - 2019/03/13 2019/03/13 rogid:vBccj/vFYRExa+isZOvQLQXm4409606 rogid:Z/EPfPB0inTUQyHKIDh172ltpaw9606 rigid:T27w7at2mmyHQ1xw9U4meYe/lbk false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O60353 uniprotkb:P47972 intact:EBI-8754490|uniprotkb:B4DRN0|uniprotkb:Q6N0A5|uniprotkb:Q6P9C3|uniprotkb:Q8WXR9|ensembl:ENSP00000351605|ensembl:ENSP00000429055 intact:EBI-3957229|ensembl:ENSP00000265634|uniprotkb:A4D267|uniprotkb:Q86XV7|uniprotkb:Q96G70 psi-mi:fzd6_human(display_long)|uniprotkb:FZD6(gene name)|psi-mi:FZD6(display_short) psi-mi:nptx2_human(display_long)|uniprotkb:NPTX2(gene name)|psi-mi:NPTX2(display_short)|uniprotkb:Neuronal pentraxin II(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xu et al. (2019) pubmed:30833544|imex:IM-27500 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-21257452|imex:IM-27500-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001304725.1|refseq:NP_001158087.1|refseq:NP_001158088.1|refseq:NP_003497.2|ensembl:ENSG00000164930(gene)|ensembl:ENST00000358755(transcript)|ensembl:ENST00000522566(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001942"(hair follicle development)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030168"(platelet activation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033278"(cell proliferation in midbrain)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0035880"(embryonic nail plate morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042813"(Wnt-activated receptor activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0048105"(establishment of body hair planar orientation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904693"(midbrain morphogenesis)|interpro:IPR000539(Frizzled protein)|interpro:IPR015526(Frizzled related)|interpro:IPR017981|interpro:IPR020067|interpro:IPR026543|interpro:IPR036790|interpro:IPR041770|reactome:R-HSA-373080|reactome:R-HSA-4086398|reactome:R-HSA-4086400|reactome:R-HSA-4641263|reactome:R-HSA-5340588|dip:DIP-59893N ensembl:ENSG00000106236(gene)|ensembl:ENST00000265634(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008306"(associative learning)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001759(Pentaxin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR030476|refseq:NP_002514.1 - - - figure legend:Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-lovo)|taxid:9606(Homo sapiens colon adenocarcinoma cell line lovo) - 2019/03/13 2019/03/13 rogid:vBccj/vFYRExa+isZOvQLQXm4409606 rogid:Z/EPfPB0inTUQyHKIDh172ltpaw9606 rigid:T27w7at2mmyHQ1xw9U4meYe/lbk false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O60353 uniprotkb:P47972 intact:EBI-8754490|uniprotkb:B4DRN0|uniprotkb:Q6N0A5|uniprotkb:Q6P9C3|uniprotkb:Q8WXR9|ensembl:ENSP00000351605|ensembl:ENSP00000429055 intact:EBI-3957229|ensembl:ENSP00000265634|uniprotkb:A4D267|uniprotkb:Q86XV7|uniprotkb:Q96G70 psi-mi:fzd6_human(display_long)|uniprotkb:FZD6(gene name)|psi-mi:FZD6(display_short) psi-mi:nptx2_human(display_long)|uniprotkb:NPTX2(gene name)|psi-mi:NPTX2(display_short)|uniprotkb:Neuronal pentraxin II(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Xu et al. (2019) pubmed:30833544|imex:IM-27500 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-21257464|imex:IM-27500-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001304725.1|refseq:NP_001158087.1|refseq:NP_001158088.1|refseq:NP_003497.2|ensembl:ENSG00000164930(gene)|ensembl:ENST00000358755(transcript)|ensembl:ENST00000522566(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001942"(hair follicle development)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030168"(platelet activation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033278"(cell proliferation in midbrain)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0035880"(embryonic nail plate morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042813"(Wnt-activated receptor activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0048105"(establishment of body hair planar orientation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904693"(midbrain morphogenesis)|interpro:IPR000539(Frizzled protein)|interpro:IPR015526(Frizzled related)|interpro:IPR017981|interpro:IPR020067|interpro:IPR026543|interpro:IPR036790|interpro:IPR041770|reactome:R-HSA-373080|reactome:R-HSA-4086398|reactome:R-HSA-4086400|reactome:R-HSA-4641263|reactome:R-HSA-5340588|dip:DIP-59893N ensembl:ENSG00000106236(gene)|ensembl:ENST00000265634(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008306"(associative learning)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001759(Pentaxin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR030476|refseq:NP_002514.1 - - - figure legend:Fig. 5E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-colorectal_cancer)|taxid:9606(human) - 2019/03/13 2019/03/13 rogid:vBccj/vFYRExa+isZOvQLQXm4409606 rogid:Z/EPfPB0inTUQyHKIDh172ltpaw9606 rigid:T27w7at2mmyHQ1xw9U4meYe/lbk false - - - - psi-mi:"MI:1198"(immunohistochemistry) psi-mi:"MI:1198"(immunohistochemistry) uniprotkb:O60353 uniprotkb:P47972 intact:EBI-8754490|uniprotkb:B4DRN0|uniprotkb:Q6N0A5|uniprotkb:Q6P9C3|uniprotkb:Q8WXR9|ensembl:ENSP00000351605|ensembl:ENSP00000429055 intact:EBI-3957229|ensembl:ENSP00000265634|uniprotkb:A4D267|uniprotkb:Q86XV7|uniprotkb:Q96G70 psi-mi:fzd6_human(display_long)|uniprotkb:FZD6(gene name)|psi-mi:FZD6(display_short) psi-mi:nptx2_human(display_long)|uniprotkb:NPTX2(gene name)|psi-mi:NPTX2(display_short)|uniprotkb:Neuronal pentraxin II(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Xu et al. (2019) pubmed:30833544|imex:IM-27500 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-21257485|imex:IM-27500-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001304725.1|refseq:NP_001158087.1|refseq:NP_001158088.1|refseq:NP_003497.2|ensembl:ENSG00000164930(gene)|ensembl:ENST00000358755(transcript)|ensembl:ENST00000522566(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001942"(hair follicle development)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030168"(platelet activation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033278"(cell proliferation in midbrain)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0035880"(embryonic nail plate morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042813"(Wnt-activated receptor activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0048105"(establishment of body hair planar orientation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904693"(midbrain morphogenesis)|interpro:IPR000539(Frizzled protein)|interpro:IPR015526(Frizzled related)|interpro:IPR017981|interpro:IPR020067|interpro:IPR026543|interpro:IPR036790|interpro:IPR041770|reactome:R-HSA-373080|reactome:R-HSA-4086398|reactome:R-HSA-4086400|reactome:R-HSA-4641263|reactome:R-HSA-5340588|dip:DIP-59893N ensembl:ENSG00000106236(gene)|ensembl:ENST00000265634(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008306"(associative learning)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001759(Pentaxin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR030476|refseq:NP_002514.1 - - - figure legend:Supp. Fig. 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sw480)|taxid:9606(Human SW480 adenocarcinoma cell line) - 2019/03/13 2019/03/13 rogid:vBccj/vFYRExa+isZOvQLQXm4409606 rogid:Z/EPfPB0inTUQyHKIDh172ltpaw9606 rigid:T27w7at2mmyHQ1xw9U4meYe/lbk false - ha tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O60353 uniprotkb:P47972 intact:EBI-8754490|uniprotkb:B4DRN0|uniprotkb:Q6N0A5|uniprotkb:Q6P9C3|uniprotkb:Q8WXR9|ensembl:ENSP00000351605|ensembl:ENSP00000429055 intact:EBI-3957229|ensembl:ENSP00000265634|uniprotkb:A4D267|uniprotkb:Q86XV7|uniprotkb:Q96G70 psi-mi:fzd6_human(display_long)|uniprotkb:FZD6(gene name)|psi-mi:FZD6(display_short) psi-mi:nptx2_human(display_long)|uniprotkb:NPTX2(gene name)|psi-mi:NPTX2(display_short)|uniprotkb:Neuronal pentraxin II(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Xu et al. (2019) pubmed:30833544|imex:IM-27500 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-21257512|imex:IM-27500-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001304725.1|refseq:NP_001158087.1|refseq:NP_001158088.1|refseq:NP_003497.2|ensembl:ENSG00000164930(gene)|ensembl:ENST00000358755(transcript)|ensembl:ENST00000522566(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001942"(hair follicle development)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030168"(platelet activation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033278"(cell proliferation in midbrain)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0035880"(embryonic nail plate morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042813"(Wnt-activated receptor activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0048105"(establishment of body hair planar orientation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904693"(midbrain morphogenesis)|interpro:IPR000539(Frizzled protein)|interpro:IPR015526(Frizzled related)|interpro:IPR017981|interpro:IPR020067|interpro:IPR026543|interpro:IPR036790|interpro:IPR041770|reactome:R-HSA-373080|reactome:R-HSA-4086398|reactome:R-HSA-4086400|reactome:R-HSA-4641263|reactome:R-HSA-5340588|dip:DIP-59893N ensembl:ENSG00000106236(gene)|ensembl:ENST00000265634(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008306"(associative learning)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001759(Pentaxin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR030476|refseq:NP_002514.1 - - - figure legend:Supp. Fig. 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-lovo)|taxid:9606(Homo sapiens colon adenocarcinoma cell line lovo) - 2019/03/13 2019/03/13 rogid:vBccj/vFYRExa+isZOvQLQXm4409606 rogid:Z/EPfPB0inTUQyHKIDh172ltpaw9606 rigid:T27w7at2mmyHQ1xw9U4meYe/lbk false - ha tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O60353 uniprotkb:P47972 intact:EBI-8754490|uniprotkb:B4DRN0|uniprotkb:Q6N0A5|uniprotkb:Q6P9C3|uniprotkb:Q8WXR9|ensembl:ENSP00000351605|ensembl:ENSP00000429055 intact:EBI-3957229|ensembl:ENSP00000265634|uniprotkb:A4D267|uniprotkb:Q86XV7|uniprotkb:Q96G70 psi-mi:fzd6_human(display_long)|uniprotkb:FZD6(gene name)|psi-mi:FZD6(display_short) psi-mi:nptx2_human(display_long)|uniprotkb:NPTX2(gene name)|psi-mi:NPTX2(display_short)|uniprotkb:Neuronal pentraxin II(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Xu et al. (2019) pubmed:30833544|imex:IM-27500 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-21257526|imex:IM-27500-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001304725.1|refseq:NP_001158087.1|refseq:NP_001158088.1|refseq:NP_003497.2|ensembl:ENSG00000164930(gene)|ensembl:ENST00000358755(transcript)|ensembl:ENST00000522566(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001942"(hair follicle development)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030168"(platelet activation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033278"(cell proliferation in midbrain)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0035880"(embryonic nail plate morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042813"(Wnt-activated receptor activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0048105"(establishment of body hair planar orientation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904693"(midbrain morphogenesis)|interpro:IPR000539(Frizzled protein)|interpro:IPR015526(Frizzled related)|interpro:IPR017981|interpro:IPR020067|interpro:IPR026543|interpro:IPR036790|interpro:IPR041770|reactome:R-HSA-373080|reactome:R-HSA-4086398|reactome:R-HSA-4086400|reactome:R-HSA-4641263|reactome:R-HSA-5340588|dip:DIP-59893N ensembl:ENSG00000106236(gene)|ensembl:ENST00000265634(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008306"(associative learning)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001759(Pentaxin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR030476|refseq:NP_002514.1 - - - figure legend:Supp. Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-lovo)|taxid:9606(Homo sapiens colon adenocarcinoma cell line lovo) - 2019/03/13 2019/03/13 rogid:vBccj/vFYRExa+isZOvQLQXm4409606 rogid:Z/EPfPB0inTUQyHKIDh172ltpaw9606 rigid:T27w7at2mmyHQ1xw9U4meYe/lbk false - - - - psi-mi:"MI:1198"(immunohistochemistry) psi-mi:"MI:1198"(immunohistochemistry) uniprotkb:O60353 uniprotkb:P47972 intact:EBI-8754490|uniprotkb:B4DRN0|uniprotkb:Q6N0A5|uniprotkb:Q6P9C3|uniprotkb:Q8WXR9|ensembl:ENSP00000351605|ensembl:ENSP00000429055 intact:EBI-3957229|ensembl:ENSP00000265634|uniprotkb:A4D267|uniprotkb:Q86XV7|uniprotkb:Q96G70 psi-mi:fzd6_human(display_long)|uniprotkb:FZD6(gene name)|psi-mi:FZD6(display_short) psi-mi:nptx2_human(display_long)|uniprotkb:NPTX2(gene name)|psi-mi:NPTX2(display_short)|uniprotkb:Neuronal pentraxin II(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Xu et al. (2019) pubmed:30833544|imex:IM-27500 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-21257537|imex:IM-27500-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001304725.1|refseq:NP_001158087.1|refseq:NP_001158088.1|refseq:NP_003497.2|ensembl:ENSG00000164930(gene)|ensembl:ENST00000358755(transcript)|ensembl:ENST00000522566(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001942"(hair follicle development)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030168"(platelet activation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033278"(cell proliferation in midbrain)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0035880"(embryonic nail plate morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042813"(Wnt-activated receptor activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0048105"(establishment of body hair planar orientation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904693"(midbrain morphogenesis)|interpro:IPR000539(Frizzled protein)|interpro:IPR015526(Frizzled related)|interpro:IPR017981|interpro:IPR020067|interpro:IPR026543|interpro:IPR036790|interpro:IPR041770|reactome:R-HSA-373080|reactome:R-HSA-4086398|reactome:R-HSA-4086400|reactome:R-HSA-4641263|reactome:R-HSA-5340588|dip:DIP-59893N ensembl:ENSG00000106236(gene)|ensembl:ENST00000265634(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008306"(associative learning)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001759(Pentaxin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR030476|refseq:NP_002514.1 - - - figure legend:Supp. Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sw480)|taxid:9606(Human SW480 adenocarcinoma cell line) - 2019/03/13 2019/03/13 rogid:vBccj/vFYRExa+isZOvQLQXm4409606 rogid:Z/EPfPB0inTUQyHKIDh172ltpaw9606 rigid:T27w7at2mmyHQ1xw9U4meYe/lbk false - - - - psi-mi:"MI:1198"(immunohistochemistry) psi-mi:"MI:1198"(immunohistochemistry)