#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
chebi:"CHEBI:31286"	uniprotkb:P14779	intact:EBI-21444780	intact:EBI-7701704|ensemblbacteria:AJI21949|intact:MINT-8313368|uniprotkb:A0A0B6AQ66|uniprotkb:Q9AE23	psi-mi:bifonazole(display_short)|psi-mi:"CHEBI:31286"(display_long)|intact:"(+-)-bifonazole"(synonym)|intact:"(+-)-1-(p,alpha-Diphenylbenzyl)imidazole"(synonym)|intact:"(+-)1-([1,1'-Biphenyl]-4-ylphenylmethyl)-1H-imidazole"(synonym)|intact:"(RS)-bifonazole"(synonym)|intact:"1-((4-Biphenylyl)phenylmethyl)-1H-imidazole"(synonym)|intact:"1-(alpha-(4-Biphenylyl)benzyl)imidazole"(synonym)|intact:bifonazol(synonym)|intact:bifonazole(synonym)|intact:bifonazolum(synonym)|intact:Mycospor(synonym)|intact:rac-bifonazole(synonym)|intact:racemic bifonazole(synonym)|intact:"rac-1-[biphenyl-4-yl(phenyl)methyl]-1H-imidazole"(iupac name)	psi-mi:cpxb_bacmb(display_long)|uniprotkb:cyp102A1(gene name)|psi-mi:cyp102A1(display_short)|uniprotkb:"Cytochrome P450(BM-3)"(gene name synonym)|uniprotkb:cyp102(gene name synonym)|uniprotkb:Cytochrome P450BM-3(gene name synonym)|uniprotkb:Fatty acid monooxygenase(gene name synonym)|uniprotkb:Flavocytochrome P450 BM3(gene name synonym)|uniprotkb:BG04_163(orf name)	psi-mi:"MI:0966"(ultraviolet-visible spectroscopy)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1348623(bacmb)|taxid:1348623(bacmb)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21444795|imex:IM-27046-61	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:5XHJ|rcsb pdb:5E7Y|rcsb pdb:4ZF6|rcsb pdb:4ZF8|rcsb pdb:4ZFA|rcsb pdb:4ZFB|rcsb pdb:5E78|rcsb pdb:5JQ2|rcsb pdb:5JQU|rcsb pdb:5JQV|rcsb pdb:5JTD|interpro:IPR023173|rcsb pdb:5XA3|ensemblbacteria:AJI21949(transcript)|ensemblbacteria:BG04_163(gene)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070330"(aromatase activity)|rcsb pdb:3WSP|rcsb pdb:5OG9|rcsb pdb:5ZLH|rcsb pdb:4RSN|rcsb pdb:6K3Q|rcsb pdb:6L1A|rcsb pdb:6L1B|rcsb pdb:1SMJ|rcsb pdb:4DUE|rcsb pdb:4DUB|rcsb pdb:3NPL|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|rcsb pdb:4HGI|rcsb pdb:4DUF|rcsb pdb:1JPZ|interpro:IPR001128(Cytochrome P450)|rcsb pdb:3DGI|rcsb pdb:2J1M|rcsb pdb:4DUC|rcsb pdb:3HF2|interpro:IPR023206|rcsb pdb:4DQK|rcsb pdb:1ZO9|rcsb pdb:3CBD|rcsb pdb:2IJ2|rcsb pdb:2UWH|rcsb pdb:1ZO4|rcsb pdb:4HGH|rcsb pdb:1JME|rcsb pdb:2X7Y|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|rcsb pdb:3KX4|rcsb pdb:1BVY|rcsb pdb:1YQP|rcsb pdb:2BMH|rcsb pdb:4DU2|rcsb pdb:3EKF|rcsb pdb:2HPD|interpro:IPR017927|rcsb pdb:3EKD|rcsb pdb:1SMI|rcsb pdb:4DUA|rcsb pdb:4DTY|rcsb pdb:3KX3|rcsb pdb:3M4V|rcsb pdb:4DUD|rcsb pdb:4HGF|rcsb pdb:4DTZ|rcsb pdb:1BU7|interpro:IPR001094(Flavodoxin-like)|rcsb pdb:2X80|rcsb pdb:1YQO|interpro:IPR017972|rcsb pdb:1FAH|rcsb pdb:3KX5|rcsb pdb:4DQL|rcsb pdb:1P0X|rcsb pdb:1P0V|rcsb pdb:3PSX|rcsb pdb:2IJ3|rcsb pdb:3EKB|interpro:IPR017938|rcsb pdb:2IJ4|rcsb pdb:4HGG|rcsb pdb:4HGJ|rcsb pdb:1P0W|rcsb pdb:3BEN|rcsb pdb:2J4S|rcsb pdb:1ZOA|rcsb pdb:2NNB|rcsb pdb:4DTW|rcsb pdb:1FAG|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|rcsb pdb:5DYP|rcsb pdb:5DYZ|rcsb pdb:5E9Z|rcsb pdb:4KPA|rcsb pdb:4KPB|rcsb pdb:4H23|rcsb pdb:4H24|rcsb pdb:4KEW|rcsb pdb:4KEY|rcsb pdb:4KF0|rcsb pdb:4KF2|rcsb pdb:4O4P|refseq:WP_034650526.1|interpro:IPR029039|rcsb pdb:4WG2|rcsb pdb:5B2U|rcsb pdb:5B2V|rcsb pdb:5B2W|rcsb pdb:5B2X|rcsb pdb:5B2Y|interpro:IPR036396|rcsb pdb:5UCW|interpro:IPR039261|rcsb pdb:5ZIS|rcsb pdb:6H1O|rcsb pdb:6H1S|rcsb pdb:6IAO|rcsb pdb:6HN8|rcsb pdb:6LY4|rcsb pdb:6JLV|rcsb pdb:6JMH|rcsb pdb:6JMW|rcsb pdb:6JO1|rcsb pdb:6JS8|rcsb pdb:6JVC|rcsb pdb:6JZS|rcsb pdb:6K58|rcsb pdb:6K9S|rcsb pdb:6K24	-	-	comment:mint	figure legend:Table 1, Figure 1, S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:3.54x10^-6 ~0.05(molar)	2019/05/29	2019/09/19	-	rogid:Oqu3y1hkk4FKpdRjfHQQkRz2qPQ1348623	-	false	-	mutation increasing interaction strength:83-83,88-88	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:3241"	uniprotkb:P14779	intact:EBI-21444804	intact:EBI-7701704|ensemblbacteria:AJI21949|intact:MINT-8313368|uniprotkb:A0A0B6AQ66|uniprotkb:Q9AE23	psi-mi:butoconazole nitrate(display_short)|psi-mi:"CHEBI:3241"(display_long)|intact:"(+-)-1-(4-(4-chlorophenyl)-2-((2,6-dichlorophenyl)thio)butyl)-1H-imidazole mononitrate"(synonym)|intact:"(+-)-1-(4-(p-chlorophenyl)-2-((2,6-dichlorophenyl)thio)butyl)imidazole mononitrate"(synonym)|intact:Butoconazole nitrate(synonym)|intact:nitrato de butoconazol(synonym)|intact:"1-{4-(4-chlorophenyl)-2-[(2,6-dichlorophenyl)sulfanyl]butyl}-1H-imidazole nitrate"(iupac name)	psi-mi:cpxb_bacmb(display_long)|uniprotkb:cyp102A1(gene name)|psi-mi:cyp102A1(display_short)|uniprotkb:"Cytochrome P450(BM-3)"(gene name synonym)|uniprotkb:cyp102(gene name synonym)|uniprotkb:Cytochrome P450BM-3(gene name synonym)|uniprotkb:Fatty acid monooxygenase(gene name synonym)|uniprotkb:Flavocytochrome P450 BM3(gene name synonym)|uniprotkb:BG04_163(orf name)	psi-mi:"MI:0966"(ultraviolet-visible spectroscopy)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1348623(bacmb)|taxid:1348623(bacmb)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21444814|imex:IM-27046-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:5XHJ|rcsb pdb:5E7Y|rcsb pdb:4ZF6|rcsb pdb:4ZF8|rcsb pdb:4ZFA|rcsb pdb:4ZFB|rcsb pdb:5E78|rcsb pdb:5JQ2|rcsb pdb:5JQU|rcsb pdb:5JQV|rcsb pdb:5JTD|interpro:IPR023173|rcsb pdb:5XA3|ensemblbacteria:AJI21949(transcript)|ensemblbacteria:BG04_163(gene)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070330"(aromatase activity)|rcsb pdb:3WSP|rcsb pdb:5OG9|rcsb pdb:5ZLH|rcsb pdb:4RSN|rcsb pdb:6K3Q|rcsb pdb:6L1A|rcsb pdb:6L1B|rcsb pdb:1SMJ|rcsb pdb:4DUE|rcsb pdb:4DUB|rcsb pdb:3NPL|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|rcsb pdb:4HGI|rcsb pdb:4DUF|rcsb pdb:1JPZ|interpro:IPR001128(Cytochrome P450)|rcsb pdb:3DGI|rcsb pdb:2J1M|rcsb pdb:4DUC|rcsb pdb:3HF2|interpro:IPR023206|rcsb pdb:4DQK|rcsb pdb:1ZO9|rcsb pdb:3CBD|rcsb pdb:2IJ2|rcsb pdb:2UWH|rcsb pdb:1ZO4|rcsb pdb:4HGH|rcsb pdb:1JME|rcsb pdb:2X7Y|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|rcsb pdb:3KX4|rcsb pdb:1BVY|rcsb pdb:1YQP|rcsb pdb:2BMH|rcsb pdb:4DU2|rcsb pdb:3EKF|rcsb pdb:2HPD|interpro:IPR017927|rcsb pdb:3EKD|rcsb pdb:1SMI|rcsb pdb:4DUA|rcsb pdb:4DTY|rcsb pdb:3KX3|rcsb pdb:3M4V|rcsb pdb:4DUD|rcsb pdb:4HGF|rcsb pdb:4DTZ|rcsb pdb:1BU7|interpro:IPR001094(Flavodoxin-like)|rcsb pdb:2X80|rcsb pdb:1YQO|interpro:IPR017972|rcsb pdb:1FAH|rcsb pdb:3KX5|rcsb pdb:4DQL|rcsb pdb:1P0X|rcsb pdb:1P0V|rcsb pdb:3PSX|rcsb pdb:2IJ3|rcsb pdb:3EKB|interpro:IPR017938|rcsb pdb:2IJ4|rcsb pdb:4HGG|rcsb pdb:4HGJ|rcsb pdb:1P0W|rcsb pdb:3BEN|rcsb pdb:2J4S|rcsb pdb:1ZOA|rcsb pdb:2NNB|rcsb pdb:4DTW|rcsb pdb:1FAG|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|rcsb pdb:5DYP|rcsb pdb:5DYZ|rcsb pdb:5E9Z|rcsb pdb:4KPA|rcsb pdb:4KPB|rcsb pdb:4H23|rcsb pdb:4H24|rcsb pdb:4KEW|rcsb pdb:4KEY|rcsb pdb:4KF0|rcsb pdb:4KF2|rcsb pdb:4O4P|refseq:WP_034650526.1|interpro:IPR029039|rcsb pdb:4WG2|rcsb pdb:5B2U|rcsb pdb:5B2V|rcsb pdb:5B2W|rcsb pdb:5B2X|rcsb pdb:5B2Y|interpro:IPR036396|rcsb pdb:5UCW|interpro:IPR039261|rcsb pdb:5ZIS|rcsb pdb:6H1O|rcsb pdb:6H1S|rcsb pdb:6IAO|rcsb pdb:6HN8|rcsb pdb:6LY4|rcsb pdb:6JLV|rcsb pdb:6JMH|rcsb pdb:6JMW|rcsb pdb:6JO1|rcsb pdb:6JS8|rcsb pdb:6JVC|rcsb pdb:6JZS|rcsb pdb:6K58|rcsb pdb:6K9S|rcsb pdb:6K24	-	-	comment:mint	figure legend:Table 1, Figure 1, S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:3.8x10^-6 ~0.12(molar)	2019/05/29	2019/09/19	-	rogid:Oqu3y1hkk4FKpdRjfHQQkRz2qPQ1348623	-	false	-	mutation increasing interaction strength:83-83,88-88	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:83499"	uniprotkb:P14779	intact:EBI-21444823	intact:EBI-7701704|ensemblbacteria:AJI21949|intact:MINT-8313368|uniprotkb:A0A0B6AQ66|uniprotkb:Q9AE23	psi-mi:climbazole(display_short)|psi-mi:"CHEBI:83499"(display_long)|intact:"rac-1-(4-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethylbutan-2-one"(iupac name)|intact:"(RS)-1-(4-chlorophenoxy)-1-imidazol-1-yl-3,3-dimethylbutan-2-one"(synonym)|intact:"1-(p-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethyl -2-butanone"(synonym)|intact:climbazol(synonym)|intact:climbazole(synonym)|intact:Climbazolum(synonym)	psi-mi:cpxb_bacmb(display_long)|uniprotkb:cyp102A1(gene name)|psi-mi:cyp102A1(display_short)|uniprotkb:"Cytochrome P450(BM-3)"(gene name synonym)|uniprotkb:cyp102(gene name synonym)|uniprotkb:Cytochrome P450BM-3(gene name synonym)|uniprotkb:Fatty acid monooxygenase(gene name synonym)|uniprotkb:Flavocytochrome P450 BM3(gene name synonym)|uniprotkb:BG04_163(orf name)	psi-mi:"MI:0966"(ultraviolet-visible spectroscopy)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1348623(bacmb)|taxid:1348623(bacmb)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21444831|imex:IM-27046-41	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:5XHJ|rcsb pdb:5E7Y|rcsb pdb:4ZF6|rcsb pdb:4ZF8|rcsb pdb:4ZFA|rcsb pdb:4ZFB|rcsb pdb:5E78|rcsb pdb:5JQ2|rcsb pdb:5JQU|rcsb pdb:5JQV|rcsb pdb:5JTD|interpro:IPR023173|rcsb pdb:5XA3|ensemblbacteria:AJI21949(transcript)|ensemblbacteria:BG04_163(gene)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070330"(aromatase activity)|rcsb pdb:3WSP|rcsb pdb:5OG9|rcsb pdb:5ZLH|rcsb pdb:4RSN|rcsb pdb:6K3Q|rcsb pdb:6L1A|rcsb pdb:6L1B|rcsb pdb:1SMJ|rcsb pdb:4DUE|rcsb pdb:4DUB|rcsb pdb:3NPL|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|rcsb pdb:4HGI|rcsb pdb:4DUF|rcsb pdb:1JPZ|interpro:IPR001128(Cytochrome P450)|rcsb pdb:3DGI|rcsb pdb:2J1M|rcsb pdb:4DUC|rcsb pdb:3HF2|interpro:IPR023206|rcsb pdb:4DQK|rcsb pdb:1ZO9|rcsb pdb:3CBD|rcsb pdb:2IJ2|rcsb pdb:2UWH|rcsb pdb:1ZO4|rcsb pdb:4HGH|rcsb pdb:1JME|rcsb pdb:2X7Y|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|rcsb pdb:3KX4|rcsb pdb:1BVY|rcsb pdb:1YQP|rcsb pdb:2BMH|rcsb pdb:4DU2|rcsb pdb:3EKF|rcsb pdb:2HPD|interpro:IPR017927|rcsb pdb:3EKD|rcsb pdb:1SMI|rcsb pdb:4DUA|rcsb pdb:4DTY|rcsb pdb:3KX3|rcsb pdb:3M4V|rcsb pdb:4DUD|rcsb pdb:4HGF|rcsb pdb:4DTZ|rcsb pdb:1BU7|interpro:IPR001094(Flavodoxin-like)|rcsb pdb:2X80|rcsb pdb:1YQO|interpro:IPR017972|rcsb pdb:1FAH|rcsb pdb:3KX5|rcsb pdb:4DQL|rcsb pdb:1P0X|rcsb pdb:1P0V|rcsb pdb:3PSX|rcsb pdb:2IJ3|rcsb pdb:3EKB|interpro:IPR017938|rcsb pdb:2IJ4|rcsb pdb:4HGG|rcsb pdb:4HGJ|rcsb pdb:1P0W|rcsb pdb:3BEN|rcsb pdb:2J4S|rcsb pdb:1ZOA|rcsb pdb:2NNB|rcsb pdb:4DTW|rcsb pdb:1FAG|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|rcsb pdb:5DYP|rcsb pdb:5DYZ|rcsb pdb:5E9Z|rcsb pdb:4KPA|rcsb pdb:4KPB|rcsb pdb:4H23|rcsb pdb:4H24|rcsb pdb:4KEW|rcsb pdb:4KEY|rcsb pdb:4KF0|rcsb pdb:4KF2|rcsb pdb:4O4P|refseq:WP_034650526.1|interpro:IPR029039|rcsb pdb:4WG2|rcsb pdb:5B2U|rcsb pdb:5B2V|rcsb pdb:5B2W|rcsb pdb:5B2X|rcsb pdb:5B2Y|interpro:IPR036396|rcsb pdb:5UCW|interpro:IPR039261|rcsb pdb:5ZIS|rcsb pdb:6H1O|rcsb pdb:6H1S|rcsb pdb:6IAO|rcsb pdb:6HN8|rcsb pdb:6LY4|rcsb pdb:6JLV|rcsb pdb:6JMH|rcsb pdb:6JMW|rcsb pdb:6JO1|rcsb pdb:6JS8|rcsb pdb:6JVC|rcsb pdb:6JZS|rcsb pdb:6K58|rcsb pdb:6K9S|rcsb pdb:6K24	-	-	comment:mint	figure legend:Table 1, Figure 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.52x10^-6 ~0.02(molar)	2019/05/29	2019/09/19	-	rogid:Oqu3y1hkk4FKpdRjfHQQkRz2qPQ1348623	-	false	-	mutation increasing interaction strength:83-83,88-88	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:3764"	uniprotkb:P14779	intact:EBI-21444840	intact:EBI-7701704|ensemblbacteria:AJI21949|intact:MINT-8313368|uniprotkb:A0A0B6AQ66|uniprotkb:Q9AE23	psi-mi:clotrimazole(display_short)|psi-mi:"CHEBI:3764"(display_long)|intact:"1-((2-Chlorophenyl)diphenylmethyl)-1H-imidazole"(synonym)|intact:"1-(alpha-(2-Chlorophenyl)benzhydryl)imidazole"(synonym)|intact:"1-(o-Chloro-alpha,alpha-diphenylbenzyl)imidazole"(synonym)|intact:"1-(o-Chlorotrityl)imidazole"(synonym)|intact:Clotrimazole(synonym)|intact:"Lotrimin (TN)"(synonym)|intact:"Mycelex (TN)"(synonym)|intact:"1-[(2-chlorophenyl)(diphenyl)methyl]-1H-imidazole"(iupac name)	psi-mi:cpxb_bacmb(display_long)|uniprotkb:cyp102A1(gene name)|psi-mi:cyp102A1(display_short)|uniprotkb:"Cytochrome P450(BM-3)"(gene name synonym)|uniprotkb:cyp102(gene name synonym)|uniprotkb:Cytochrome P450BM-3(gene name synonym)|uniprotkb:Fatty acid monooxygenase(gene name synonym)|uniprotkb:Flavocytochrome P450 BM3(gene name synonym)|uniprotkb:BG04_163(orf name)	psi-mi:"MI:0966"(ultraviolet-visible spectroscopy)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1348623(bacmb)|taxid:1348623(bacmb)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21444853|imex:IM-27046-63	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:5XHJ|rcsb pdb:5E7Y|rcsb pdb:4ZF6|rcsb pdb:4ZF8|rcsb pdb:4ZFA|rcsb pdb:4ZFB|rcsb pdb:5E78|rcsb pdb:5JQ2|rcsb pdb:5JQU|rcsb pdb:5JQV|rcsb pdb:5JTD|interpro:IPR023173|rcsb pdb:5XA3|ensemblbacteria:AJI21949(transcript)|ensemblbacteria:BG04_163(gene)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070330"(aromatase activity)|rcsb pdb:3WSP|rcsb pdb:5OG9|rcsb pdb:5ZLH|rcsb pdb:4RSN|rcsb pdb:6K3Q|rcsb pdb:6L1A|rcsb pdb:6L1B|rcsb pdb:1SMJ|rcsb pdb:4DUE|rcsb pdb:4DUB|rcsb pdb:3NPL|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|rcsb pdb:4HGI|rcsb pdb:4DUF|rcsb pdb:1JPZ|interpro:IPR001128(Cytochrome P450)|rcsb pdb:3DGI|rcsb pdb:2J1M|rcsb pdb:4DUC|rcsb pdb:3HF2|interpro:IPR023206|rcsb pdb:4DQK|rcsb pdb:1ZO9|rcsb pdb:3CBD|rcsb pdb:2IJ2|rcsb pdb:2UWH|rcsb pdb:1ZO4|rcsb pdb:4HGH|rcsb pdb:1JME|rcsb pdb:2X7Y|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|rcsb pdb:3KX4|rcsb pdb:1BVY|rcsb pdb:1YQP|rcsb pdb:2BMH|rcsb pdb:4DU2|rcsb pdb:3EKF|rcsb pdb:2HPD|interpro:IPR017927|rcsb pdb:3EKD|rcsb pdb:1SMI|rcsb pdb:4DUA|rcsb pdb:4DTY|rcsb pdb:3KX3|rcsb pdb:3M4V|rcsb pdb:4DUD|rcsb pdb:4HGF|rcsb pdb:4DTZ|rcsb pdb:1BU7|interpro:IPR001094(Flavodoxin-like)|rcsb pdb:2X80|rcsb pdb:1YQO|interpro:IPR017972|rcsb pdb:1FAH|rcsb pdb:3KX5|rcsb pdb:4DQL|rcsb pdb:1P0X|rcsb pdb:1P0V|rcsb pdb:3PSX|rcsb pdb:2IJ3|rcsb pdb:3EKB|interpro:IPR017938|rcsb pdb:2IJ4|rcsb pdb:4HGG|rcsb pdb:4HGJ|rcsb pdb:1P0W|rcsb pdb:3BEN|rcsb pdb:2J4S|rcsb pdb:1ZOA|rcsb pdb:2NNB|rcsb pdb:4DTW|rcsb pdb:1FAG|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|rcsb pdb:5DYP|rcsb pdb:5DYZ|rcsb pdb:5E9Z|rcsb pdb:4KPA|rcsb pdb:4KPB|rcsb pdb:4H23|rcsb pdb:4H24|rcsb pdb:4KEW|rcsb pdb:4KEY|rcsb pdb:4KF0|rcsb pdb:4KF2|rcsb pdb:4O4P|refseq:WP_034650526.1|interpro:IPR029039|rcsb pdb:4WG2|rcsb pdb:5B2U|rcsb pdb:5B2V|rcsb pdb:5B2W|rcsb pdb:5B2X|rcsb pdb:5B2Y|interpro:IPR036396|rcsb pdb:5UCW|interpro:IPR039261|rcsb pdb:5ZIS|rcsb pdb:6H1O|rcsb pdb:6H1S|rcsb pdb:6IAO|rcsb pdb:6HN8|rcsb pdb:6LY4|rcsb pdb:6JLV|rcsb pdb:6JMH|rcsb pdb:6JMW|rcsb pdb:6JO1|rcsb pdb:6JS8|rcsb pdb:6JVC|rcsb pdb:6JZS|rcsb pdb:6K58|rcsb pdb:6K9S|rcsb pdb:6K24	-	-	comment:mint	figure legend:Table 1, Figure 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:32.8x10^-6 ~1.9(molar)	2019/05/29	2019/09/19	-	rogid:Oqu3y1hkk4FKpdRjfHQQkRz2qPQ1348623	-	false	-	mutation increasing interaction strength:83-83,88-88	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:4755"	uniprotkb:P14779	intact:EBI-21444862	intact:EBI-7701704|ensemblbacteria:AJI21949|intact:MINT-8313368|uniprotkb:A0A0B6AQ66|uniprotkb:Q9AE23	psi-mi:econazole nitrate(display_short)|psi-mi:"CHEBI:4755"(display_long)|intact:"(+-)-econazole nitrate"(synonym)|intact:"(RS)-econazole nitrate"(synonym)|intact:"1-(2,4-Dichloro-beta-((p-chlorobenzyl)oxy)phenethyl)imidazole nitrate"(synonym)|intact:Econazole mononitrate(synonym)|intact:rac-econazole nitrate(synonym)|intact:Spectazole(synonym)|intact:"1-{2-[(4-chlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole nitrate"(iupac name)	psi-mi:cpxb_bacmb(display_long)|uniprotkb:cyp102A1(gene name)|psi-mi:cyp102A1(display_short)|uniprotkb:"Cytochrome P450(BM-3)"(gene name synonym)|uniprotkb:cyp102(gene name synonym)|uniprotkb:Cytochrome P450BM-3(gene name synonym)|uniprotkb:Fatty acid monooxygenase(gene name synonym)|uniprotkb:Flavocytochrome P450 BM3(gene name synonym)|uniprotkb:BG04_163(orf name)	psi-mi:"MI:0966"(ultraviolet-visible spectroscopy)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1348623(bacmb)|taxid:1348623(bacmb)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21444871|imex:IM-27046-43	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:5XHJ|rcsb pdb:5E7Y|rcsb pdb:4ZF6|rcsb pdb:4ZF8|rcsb pdb:4ZFA|rcsb pdb:4ZFB|rcsb pdb:5E78|rcsb pdb:5JQ2|rcsb pdb:5JQU|rcsb pdb:5JQV|rcsb pdb:5JTD|interpro:IPR023173|rcsb pdb:5XA3|ensemblbacteria:AJI21949(transcript)|ensemblbacteria:BG04_163(gene)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070330"(aromatase activity)|rcsb pdb:3WSP|rcsb pdb:5OG9|rcsb pdb:5ZLH|rcsb pdb:4RSN|rcsb pdb:6K3Q|rcsb pdb:6L1A|rcsb pdb:6L1B|rcsb pdb:1SMJ|rcsb pdb:4DUE|rcsb pdb:4DUB|rcsb pdb:3NPL|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|rcsb pdb:4HGI|rcsb pdb:4DUF|rcsb pdb:1JPZ|interpro:IPR001128(Cytochrome P450)|rcsb pdb:3DGI|rcsb pdb:2J1M|rcsb pdb:4DUC|rcsb pdb:3HF2|interpro:IPR023206|rcsb pdb:4DQK|rcsb pdb:1ZO9|rcsb pdb:3CBD|rcsb pdb:2IJ2|rcsb pdb:2UWH|rcsb pdb:1ZO4|rcsb pdb:4HGH|rcsb pdb:1JME|rcsb pdb:2X7Y|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|rcsb pdb:3KX4|rcsb pdb:1BVY|rcsb pdb:1YQP|rcsb pdb:2BMH|rcsb pdb:4DU2|rcsb pdb:3EKF|rcsb pdb:2HPD|interpro:IPR017927|rcsb pdb:3EKD|rcsb pdb:1SMI|rcsb pdb:4DUA|rcsb pdb:4DTY|rcsb pdb:3KX3|rcsb pdb:3M4V|rcsb pdb:4DUD|rcsb pdb:4HGF|rcsb pdb:4DTZ|rcsb pdb:1BU7|interpro:IPR001094(Flavodoxin-like)|rcsb pdb:2X80|rcsb pdb:1YQO|interpro:IPR017972|rcsb pdb:1FAH|rcsb pdb:3KX5|rcsb pdb:4DQL|rcsb pdb:1P0X|rcsb pdb:1P0V|rcsb pdb:3PSX|rcsb pdb:2IJ3|rcsb pdb:3EKB|interpro:IPR017938|rcsb pdb:2IJ4|rcsb pdb:4HGG|rcsb pdb:4HGJ|rcsb pdb:1P0W|rcsb pdb:3BEN|rcsb pdb:2J4S|rcsb pdb:1ZOA|rcsb pdb:2NNB|rcsb pdb:4DTW|rcsb pdb:1FAG|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|rcsb pdb:5DYP|rcsb pdb:5DYZ|rcsb pdb:5E9Z|rcsb pdb:4KPA|rcsb pdb:4KPB|rcsb pdb:4H23|rcsb pdb:4H24|rcsb pdb:4KEW|rcsb pdb:4KEY|rcsb pdb:4KF0|rcsb pdb:4KF2|rcsb pdb:4O4P|refseq:WP_034650526.1|interpro:IPR029039|rcsb pdb:4WG2|rcsb pdb:5B2U|rcsb pdb:5B2V|rcsb pdb:5B2W|rcsb pdb:5B2X|rcsb pdb:5B2Y|interpro:IPR036396|rcsb pdb:5UCW|interpro:IPR039261|rcsb pdb:5ZIS|rcsb pdb:6H1O|rcsb pdb:6H1S|rcsb pdb:6IAO|rcsb pdb:6HN8|rcsb pdb:6LY4|rcsb pdb:6JLV|rcsb pdb:6JMH|rcsb pdb:6JMW|rcsb pdb:6JO1|rcsb pdb:6JS8|rcsb pdb:6JVC|rcsb pdb:6JZS|rcsb pdb:6K58|rcsb pdb:6K9S|rcsb pdb:6K24	-	-	comment:mint	figure legend:Table 1, Figure 1, S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:19.3x10^-6 ~0.27(molar)	2019/05/29	2019/09/19	-	rogid:Oqu3y1hkk4FKpdRjfHQQkRz2qPQ1348623	-	false	-	mutation increasing interaction strength:88-88,83-83	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:83606"	uniprotkb:P14779	intact:EBI-21444917	intact:EBI-7701704|ensemblbacteria:AJI21949|intact:MINT-8313368|uniprotkb:A0A0B6AQ66|uniprotkb:Q9AE23	psi-mi:fenticonazole nitrate(display_short)|psi-mi:"CHEBI:83606"(display_long)|intact:"(+-)-1-(2,4-Dichloro-beta-((p-(phenylthio)benzyl)oxy)phenethyl)imidazole mononitrate"(synonym)|intact:"alpha-(2,4-Dichlorophenyl)-beta,N-imidazolylethyl-4-phenylthiobenzyl ether nitrate"(synonym)|intact:fenticonazole mononitrate(synonym)|intact:Lomexin(synonym)|intact:"rac-1-[2-(2,4-dichlorophenyl)-2-{[4-(phenylsulfanyl)benzyl]oxy}ethyl]-1H-imidazole nitrate"(iupac name)	psi-mi:cpxb_bacmb(display_long)|uniprotkb:cyp102A1(gene name)|psi-mi:cyp102A1(display_short)|uniprotkb:"Cytochrome P450(BM-3)"(gene name synonym)|uniprotkb:cyp102(gene name synonym)|uniprotkb:Cytochrome P450BM-3(gene name synonym)|uniprotkb:Fatty acid monooxygenase(gene name synonym)|uniprotkb:Flavocytochrome P450 BM3(gene name synonym)|uniprotkb:BG04_163(orf name)	psi-mi:"MI:0966"(ultraviolet-visible spectroscopy)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1348623(bacmb)|taxid:1348623(bacmb)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21444897|imex:IM-27046-65	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:5XHJ|rcsb pdb:5E7Y|rcsb pdb:4ZF6|rcsb pdb:4ZF8|rcsb pdb:4ZFA|rcsb pdb:4ZFB|rcsb pdb:5E78|rcsb pdb:5JQ2|rcsb pdb:5JQU|rcsb pdb:5JQV|rcsb pdb:5JTD|interpro:IPR023173|rcsb pdb:5XA3|ensemblbacteria:AJI21949(transcript)|ensemblbacteria:BG04_163(gene)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070330"(aromatase activity)|rcsb pdb:3WSP|rcsb pdb:5OG9|rcsb pdb:5ZLH|rcsb pdb:4RSN|rcsb pdb:6K3Q|rcsb pdb:6L1A|rcsb pdb:6L1B|rcsb pdb:1SMJ|rcsb pdb:4DUE|rcsb pdb:4DUB|rcsb pdb:3NPL|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|rcsb pdb:4HGI|rcsb pdb:4DUF|rcsb pdb:1JPZ|interpro:IPR001128(Cytochrome P450)|rcsb pdb:3DGI|rcsb pdb:2J1M|rcsb pdb:4DUC|rcsb pdb:3HF2|interpro:IPR023206|rcsb pdb:4DQK|rcsb pdb:1ZO9|rcsb pdb:3CBD|rcsb pdb:2IJ2|rcsb pdb:2UWH|rcsb pdb:1ZO4|rcsb pdb:4HGH|rcsb pdb:1JME|rcsb pdb:2X7Y|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|rcsb pdb:3KX4|rcsb pdb:1BVY|rcsb pdb:1YQP|rcsb pdb:2BMH|rcsb pdb:4DU2|rcsb pdb:3EKF|rcsb pdb:2HPD|interpro:IPR017927|rcsb pdb:3EKD|rcsb pdb:1SMI|rcsb pdb:4DUA|rcsb pdb:4DTY|rcsb pdb:3KX3|rcsb pdb:3M4V|rcsb pdb:4DUD|rcsb pdb:4HGF|rcsb pdb:4DTZ|rcsb pdb:1BU7|interpro:IPR001094(Flavodoxin-like)|rcsb pdb:2X80|rcsb pdb:1YQO|interpro:IPR017972|rcsb pdb:1FAH|rcsb pdb:3KX5|rcsb pdb:4DQL|rcsb pdb:1P0X|rcsb pdb:1P0V|rcsb pdb:3PSX|rcsb pdb:2IJ3|rcsb pdb:3EKB|interpro:IPR017938|rcsb pdb:2IJ4|rcsb pdb:4HGG|rcsb pdb:4HGJ|rcsb pdb:1P0W|rcsb pdb:3BEN|rcsb pdb:2J4S|rcsb pdb:1ZOA|rcsb pdb:2NNB|rcsb pdb:4DTW|rcsb pdb:1FAG|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|rcsb pdb:5DYP|rcsb pdb:5DYZ|rcsb pdb:5E9Z|rcsb pdb:4KPA|rcsb pdb:4KPB|rcsb pdb:4H23|rcsb pdb:4H24|rcsb pdb:4KEW|rcsb pdb:4KEY|rcsb pdb:4KF0|rcsb pdb:4KF2|rcsb pdb:4O4P|refseq:WP_034650526.1|interpro:IPR029039|rcsb pdb:4WG2|rcsb pdb:5B2U|rcsb pdb:5B2V|rcsb pdb:5B2W|rcsb pdb:5B2X|rcsb pdb:5B2Y|interpro:IPR036396|rcsb pdb:5UCW|interpro:IPR039261|rcsb pdb:5ZIS|rcsb pdb:6H1O|rcsb pdb:6H1S|rcsb pdb:6IAO|rcsb pdb:6HN8|rcsb pdb:6LY4|rcsb pdb:6JLV|rcsb pdb:6JMH|rcsb pdb:6JMW|rcsb pdb:6JO1|rcsb pdb:6JS8|rcsb pdb:6JVC|rcsb pdb:6JZS|rcsb pdb:6K58|rcsb pdb:6K9S|rcsb pdb:6K24	-	-	comment:mint	figure legend:Table 1, Figure 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.89x10^-6 ~0.05(molar)	2019/05/29	2019/09/19	-	rogid:Oqu3y1hkk4FKpdRjfHQQkRz2qPQ1348623	-	false	-	mutation increasing interaction strength:83-83,88-88	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:31728"	uniprotkb:P14779	intact:EBI-21444928	intact:EBI-7701704|ensemblbacteria:AJI21949|intact:MINT-8313368|uniprotkb:A0A0B6AQ66|uniprotkb:Q9AE23	psi-mi:isoconazole nitrate(display_short)|psi-mi:"CHEBI:31728"(display_long)|intact:"(+-)-isoconazole nitrate"(synonym)|intact:"(RS)-isoconazole nitrate"(synonym)|intact:"1-(2,4-Dichloro-beta-(2,6-dichlorobenzyloxy)phenethyl)imidazole nitrate"(synonym)|intact:"1-(2-((2,6-Dichlorobenzyl)oxy)-2-(2,4-dichlorophenyl)ethyl)imidazole nitrate"(synonym)|intact:isoconazole mononitrate(synonym)|intact:rac-isoconazole nitrate(synonym)|intact:racemic isoconazole nitrate(synonym)|intact:"rac-1-{2-[(2,6-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole nitrate"(iupac name)	psi-mi:cpxb_bacmb(display_long)|uniprotkb:cyp102A1(gene name)|psi-mi:cyp102A1(display_short)|uniprotkb:"Cytochrome P450(BM-3)"(gene name synonym)|uniprotkb:cyp102(gene name synonym)|uniprotkb:Cytochrome P450BM-3(gene name synonym)|uniprotkb:Fatty acid monooxygenase(gene name synonym)|uniprotkb:Flavocytochrome P450 BM3(gene name synonym)|uniprotkb:BG04_163(orf name)	psi-mi:"MI:0966"(ultraviolet-visible spectroscopy)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1348623(bacmb)|taxid:1348623(bacmb)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21444938|imex:IM-27046-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:5XHJ|rcsb pdb:5E7Y|rcsb pdb:4ZF6|rcsb pdb:4ZF8|rcsb pdb:4ZFA|rcsb pdb:4ZFB|rcsb pdb:5E78|rcsb pdb:5JQ2|rcsb pdb:5JQU|rcsb pdb:5JQV|rcsb pdb:5JTD|interpro:IPR023173|rcsb pdb:5XA3|ensemblbacteria:AJI21949(transcript)|ensemblbacteria:BG04_163(gene)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070330"(aromatase activity)|rcsb pdb:3WSP|rcsb pdb:5OG9|rcsb pdb:5ZLH|rcsb pdb:4RSN|rcsb pdb:6K3Q|rcsb pdb:6L1A|rcsb pdb:6L1B|rcsb pdb:1SMJ|rcsb pdb:4DUE|rcsb pdb:4DUB|rcsb pdb:3NPL|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|rcsb pdb:4HGI|rcsb pdb:4DUF|rcsb pdb:1JPZ|interpro:IPR001128(Cytochrome P450)|rcsb pdb:3DGI|rcsb pdb:2J1M|rcsb pdb:4DUC|rcsb pdb:3HF2|interpro:IPR023206|rcsb pdb:4DQK|rcsb pdb:1ZO9|rcsb pdb:3CBD|rcsb pdb:2IJ2|rcsb pdb:2UWH|rcsb pdb:1ZO4|rcsb pdb:4HGH|rcsb pdb:1JME|rcsb pdb:2X7Y|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|rcsb pdb:3KX4|rcsb pdb:1BVY|rcsb pdb:1YQP|rcsb pdb:2BMH|rcsb pdb:4DU2|rcsb pdb:3EKF|rcsb pdb:2HPD|interpro:IPR017927|rcsb pdb:3EKD|rcsb pdb:1SMI|rcsb pdb:4DUA|rcsb pdb:4DTY|rcsb pdb:3KX3|rcsb pdb:3M4V|rcsb pdb:4DUD|rcsb pdb:4HGF|rcsb pdb:4DTZ|rcsb pdb:1BU7|interpro:IPR001094(Flavodoxin-like)|rcsb pdb:2X80|rcsb pdb:1YQO|interpro:IPR017972|rcsb pdb:1FAH|rcsb pdb:3KX5|rcsb pdb:4DQL|rcsb pdb:1P0X|rcsb pdb:1P0V|rcsb pdb:3PSX|rcsb pdb:2IJ3|rcsb pdb:3EKB|interpro:IPR017938|rcsb pdb:2IJ4|rcsb pdb:4HGG|rcsb pdb:4HGJ|rcsb pdb:1P0W|rcsb pdb:3BEN|rcsb pdb:2J4S|rcsb pdb:1ZOA|rcsb pdb:2NNB|rcsb pdb:4DTW|rcsb pdb:1FAG|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|rcsb pdb:5DYP|rcsb pdb:5DYZ|rcsb pdb:5E9Z|rcsb pdb:4KPA|rcsb pdb:4KPB|rcsb pdb:4H23|rcsb pdb:4H24|rcsb pdb:4KEW|rcsb pdb:4KEY|rcsb pdb:4KF0|rcsb pdb:4KF2|rcsb pdb:4O4P|refseq:WP_034650526.1|interpro:IPR029039|rcsb pdb:4WG2|rcsb pdb:5B2U|rcsb pdb:5B2V|rcsb pdb:5B2W|rcsb pdb:5B2X|rcsb pdb:5B2Y|interpro:IPR036396|rcsb pdb:5UCW|interpro:IPR039261|rcsb pdb:5ZIS|rcsb pdb:6H1O|rcsb pdb:6H1S|rcsb pdb:6IAO|rcsb pdb:6HN8|rcsb pdb:6LY4|rcsb pdb:6JLV|rcsb pdb:6JMH|rcsb pdb:6JMW|rcsb pdb:6JO1|rcsb pdb:6JS8|rcsb pdb:6JVC|rcsb pdb:6JZS|rcsb pdb:6K58|rcsb pdb:6K9S|rcsb pdb:6K24	-	-	comment:mint	figure legend:Table 1, Figure 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:12.0x10^-6 ~0.5(molar)	2019/05/29	2019/09/19	-	rogid:Oqu3y1hkk4FKpdRjfHQQkRz2qPQ1348623	-	false	-	mutation increasing interaction strength:83-83,88-88	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:47519"	uniprotkb:P14779	intact:EBI-21444955|chebi:"CHEBI:6126"	intact:EBI-7701704|ensemblbacteria:AJI21949|intact:MINT-8313368|uniprotkb:A0A0B6AQ66|uniprotkb:Q9AE23	psi-mi:ketoconazole(display_short)|psi-mi:"CHEBI:47519"(display_long)|intact:Fungarest(synonym)|intact:Fungoral(synonym)|intact:ketoconazol(synonym)|intact:ketoconazole(synonym)|intact:ketoconazolum(synonym)|intact:Ketoderm(synonym)|intact:Ketoisdin(synonym)|intact:Nizoral(synonym)|intact:Panfungol(synonym)|intact:Xolegel(synonym)|intact:"rac-1-acetyl-4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine"(iupac name)|intact:"(+-)-cis-1-acetyl-4-(p-((2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazine"(synonym)|intact:"cis-1-acetyl-4-(4-((2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazine"(synonym)	psi-mi:cpxb_bacmb(display_long)|uniprotkb:cyp102A1(gene name)|psi-mi:cyp102A1(display_short)|uniprotkb:"Cytochrome P450(BM-3)"(gene name synonym)|uniprotkb:cyp102(gene name synonym)|uniprotkb:Cytochrome P450BM-3(gene name synonym)|uniprotkb:Fatty acid monooxygenase(gene name synonym)|uniprotkb:Flavocytochrome P450 BM3(gene name synonym)|uniprotkb:BG04_163(orf name)	psi-mi:"MI:0966"(ultraviolet-visible spectroscopy)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1348623(bacmb)|taxid:1348623(bacmb)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21444971|imex:IM-27046-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:5XHJ|rcsb pdb:5E7Y|rcsb pdb:4ZF6|rcsb pdb:4ZF8|rcsb pdb:4ZFA|rcsb pdb:4ZFB|rcsb pdb:5E78|rcsb pdb:5JQ2|rcsb pdb:5JQU|rcsb pdb:5JQV|rcsb pdb:5JTD|interpro:IPR023173|rcsb pdb:5XA3|ensemblbacteria:AJI21949(transcript)|ensemblbacteria:BG04_163(gene)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070330"(aromatase activity)|rcsb pdb:3WSP|rcsb pdb:5OG9|rcsb pdb:5ZLH|rcsb pdb:4RSN|rcsb pdb:6K3Q|rcsb pdb:6L1A|rcsb pdb:6L1B|rcsb pdb:1SMJ|rcsb pdb:4DUE|rcsb pdb:4DUB|rcsb pdb:3NPL|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|rcsb pdb:4HGI|rcsb pdb:4DUF|rcsb pdb:1JPZ|interpro:IPR001128(Cytochrome P450)|rcsb pdb:3DGI|rcsb pdb:2J1M|rcsb pdb:4DUC|rcsb pdb:3HF2|interpro:IPR023206|rcsb pdb:4DQK|rcsb pdb:1ZO9|rcsb pdb:3CBD|rcsb pdb:2IJ2|rcsb pdb:2UWH|rcsb pdb:1ZO4|rcsb pdb:4HGH|rcsb pdb:1JME|rcsb pdb:2X7Y|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|rcsb pdb:3KX4|rcsb pdb:1BVY|rcsb pdb:1YQP|rcsb pdb:2BMH|rcsb pdb:4DU2|rcsb pdb:3EKF|rcsb pdb:2HPD|interpro:IPR017927|rcsb pdb:3EKD|rcsb pdb:1SMI|rcsb pdb:4DUA|rcsb pdb:4DTY|rcsb pdb:3KX3|rcsb pdb:3M4V|rcsb pdb:4DUD|rcsb pdb:4HGF|rcsb pdb:4DTZ|rcsb pdb:1BU7|interpro:IPR001094(Flavodoxin-like)|rcsb pdb:2X80|rcsb pdb:1YQO|interpro:IPR017972|rcsb pdb:1FAH|rcsb pdb:3KX5|rcsb pdb:4DQL|rcsb pdb:1P0X|rcsb pdb:1P0V|rcsb pdb:3PSX|rcsb pdb:2IJ3|rcsb pdb:3EKB|interpro:IPR017938|rcsb pdb:2IJ4|rcsb pdb:4HGG|rcsb pdb:4HGJ|rcsb pdb:1P0W|rcsb pdb:3BEN|rcsb pdb:2J4S|rcsb pdb:1ZOA|rcsb pdb:2NNB|rcsb pdb:4DTW|rcsb pdb:1FAG|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|rcsb pdb:5DYP|rcsb pdb:5DYZ|rcsb pdb:5E9Z|rcsb pdb:4KPA|rcsb pdb:4KPB|rcsb pdb:4H23|rcsb pdb:4H24|rcsb pdb:4KEW|rcsb pdb:4KEY|rcsb pdb:4KF0|rcsb pdb:4KF2|rcsb pdb:4O4P|refseq:WP_034650526.1|interpro:IPR029039|rcsb pdb:4WG2|rcsb pdb:5B2U|rcsb pdb:5B2V|rcsb pdb:5B2W|rcsb pdb:5B2X|rcsb pdb:5B2Y|interpro:IPR036396|rcsb pdb:5UCW|interpro:IPR039261|rcsb pdb:5ZIS|rcsb pdb:6H1O|rcsb pdb:6H1S|rcsb pdb:6IAO|rcsb pdb:6HN8|rcsb pdb:6LY4|rcsb pdb:6JLV|rcsb pdb:6JMH|rcsb pdb:6JMW|rcsb pdb:6JO1|rcsb pdb:6JS8|rcsb pdb:6JVC|rcsb pdb:6JZS|rcsb pdb:6K58|rcsb pdb:6K9S|rcsb pdb:6K24	-	-	comment:mint	figure legend:Table 1, Figure 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:4.41x10^-6 ~0.15(molar)	2019/05/29	2019/09/19	-	rogid:Oqu3y1hkk4FKpdRjfHQQkRz2qPQ1348623	-	false	-	mutation increasing interaction strength:83-83,88-88	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:6923"	uniprotkb:P14779	intact:EBI-21444994|chebi:"CHEBI:108917"	intact:EBI-7701704|ensemblbacteria:AJI21949|intact:MINT-8313368|uniprotkb:A0A0B6AQ66|uniprotkb:Q9AE23	psi-mi:miconazole(display_short)|psi-mi:"CHEBI:6923"(display_long)|intact:"(+-)-miconazole"(synonym)|intact:"(RS)-miconazole"(synonym)|intact:"1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole"(synonym)|intact:"1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole"(synonym)|intact:Daktarin IV(synonym)|intact:Miconazole(synonym)|intact:"Monistat IV (TN)"(synonym)|intact:rac-miconazole(synonym)|intact:"rac-1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole"(iupac name)	psi-mi:cpxb_bacmb(display_long)|uniprotkb:cyp102A1(gene name)|psi-mi:cyp102A1(display_short)|uniprotkb:"Cytochrome P450(BM-3)"(gene name synonym)|uniprotkb:cyp102(gene name synonym)|uniprotkb:Cytochrome P450BM-3(gene name synonym)|uniprotkb:Fatty acid monooxygenase(gene name synonym)|uniprotkb:Flavocytochrome P450 BM3(gene name synonym)|uniprotkb:BG04_163(orf name)	psi-mi:"MI:0966"(ultraviolet-visible spectroscopy)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1348623(bacmb)|taxid:1348623(bacmb)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21445006|imex:IM-27046-67	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:5XHJ|rcsb pdb:5E7Y|rcsb pdb:4ZF6|rcsb pdb:4ZF8|rcsb pdb:4ZFA|rcsb pdb:4ZFB|rcsb pdb:5E78|rcsb pdb:5JQ2|rcsb pdb:5JQU|rcsb pdb:5JQV|rcsb pdb:5JTD|interpro:IPR023173|rcsb pdb:5XA3|ensemblbacteria:AJI21949(transcript)|ensemblbacteria:BG04_163(gene)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070330"(aromatase activity)|rcsb pdb:3WSP|rcsb pdb:5OG9|rcsb pdb:5ZLH|rcsb pdb:4RSN|rcsb pdb:6K3Q|rcsb pdb:6L1A|rcsb pdb:6L1B|rcsb pdb:1SMJ|rcsb pdb:4DUE|rcsb pdb:4DUB|rcsb pdb:3NPL|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|rcsb pdb:4HGI|rcsb pdb:4DUF|rcsb pdb:1JPZ|interpro:IPR001128(Cytochrome P450)|rcsb pdb:3DGI|rcsb pdb:2J1M|rcsb pdb:4DUC|rcsb pdb:3HF2|interpro:IPR023206|rcsb pdb:4DQK|rcsb pdb:1ZO9|rcsb pdb:3CBD|rcsb pdb:2IJ2|rcsb pdb:2UWH|rcsb pdb:1ZO4|rcsb pdb:4HGH|rcsb pdb:1JME|rcsb pdb:2X7Y|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|rcsb pdb:3KX4|rcsb pdb:1BVY|rcsb pdb:1YQP|rcsb pdb:2BMH|rcsb pdb:4DU2|rcsb pdb:3EKF|rcsb pdb:2HPD|interpro:IPR017927|rcsb pdb:3EKD|rcsb pdb:1SMI|rcsb pdb:4DUA|rcsb pdb:4DTY|rcsb pdb:3KX3|rcsb pdb:3M4V|rcsb pdb:4DUD|rcsb pdb:4HGF|rcsb pdb:4DTZ|rcsb pdb:1BU7|interpro:IPR001094(Flavodoxin-like)|rcsb pdb:2X80|rcsb pdb:1YQO|interpro:IPR017972|rcsb pdb:1FAH|rcsb pdb:3KX5|rcsb pdb:4DQL|rcsb pdb:1P0X|rcsb pdb:1P0V|rcsb pdb:3PSX|rcsb pdb:2IJ3|rcsb pdb:3EKB|interpro:IPR017938|rcsb pdb:2IJ4|rcsb pdb:4HGG|rcsb pdb:4HGJ|rcsb pdb:1P0W|rcsb pdb:3BEN|rcsb pdb:2J4S|rcsb pdb:1ZOA|rcsb pdb:2NNB|rcsb pdb:4DTW|rcsb pdb:1FAG|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|rcsb pdb:5DYP|rcsb pdb:5DYZ|rcsb pdb:5E9Z|rcsb pdb:4KPA|rcsb pdb:4KPB|rcsb pdb:4H23|rcsb pdb:4H24|rcsb pdb:4KEW|rcsb pdb:4KEY|rcsb pdb:4KF0|rcsb pdb:4KF2|rcsb pdb:4O4P|refseq:WP_034650526.1|interpro:IPR029039|rcsb pdb:4WG2|rcsb pdb:5B2U|rcsb pdb:5B2V|rcsb pdb:5B2W|rcsb pdb:5B2X|rcsb pdb:5B2Y|interpro:IPR036396|rcsb pdb:5UCW|interpro:IPR039261|rcsb pdb:5ZIS|rcsb pdb:6H1O|rcsb pdb:6H1S|rcsb pdb:6IAO|rcsb pdb:6HN8|rcsb pdb:6LY4|rcsb pdb:6JLV|rcsb pdb:6JMH|rcsb pdb:6JMW|rcsb pdb:6JO1|rcsb pdb:6JS8|rcsb pdb:6JVC|rcsb pdb:6JZS|rcsb pdb:6K58|rcsb pdb:6K9S|rcsb pdb:6K24	-	-	comment:mint	figure legend:Table 1, Figure 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:6.94x10^-6 ~0.15(molar)	2019/05/29	2019/09/19	-	rogid:Oqu3y1hkk4FKpdRjfHQQkRz2qPQ1348623	-	false	-	mutation increasing interaction strength:83-83,88-88	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:83687"	uniprotkb:P14779	intact:EBI-21445017	intact:EBI-7701704|ensemblbacteria:AJI21949|intact:MINT-8313368|uniprotkb:A0A0B6AQ66|uniprotkb:Q9AE23	psi-mi:sertaconazole nitrate(display_short)|psi-mi:"CHEBI:83687"(display_long)|intact:"(+-)-sertaconazole nitrate"(synonym)|intact:"(RS)-sertaconazole nitrate"(synonym)|intact:Ertaczo(synonym)|intact:rac-sertaconazole nitrate(synonym)|intact:racemic sertaconazole nitrate(synonym)|intact:sertaconazole mononitrate(synonym)|intact:Zalain(synonym)|intact:"rac-1-{2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole nitrate"(iupac name)	psi-mi:cpxb_bacmb(display_long)|uniprotkb:cyp102A1(gene name)|psi-mi:cyp102A1(display_short)|uniprotkb:"Cytochrome P450(BM-3)"(gene name synonym)|uniprotkb:cyp102(gene name synonym)|uniprotkb:Cytochrome P450BM-3(gene name synonym)|uniprotkb:Fatty acid monooxygenase(gene name synonym)|uniprotkb:Flavocytochrome P450 BM3(gene name synonym)|uniprotkb:BG04_163(orf name)	psi-mi:"MI:0966"(ultraviolet-visible spectroscopy)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1348623(bacmb)|taxid:1348623(bacmb)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21445027|imex:IM-27046-69	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:5XHJ|rcsb pdb:5E7Y|rcsb pdb:4ZF6|rcsb pdb:4ZF8|rcsb pdb:4ZFA|rcsb pdb:4ZFB|rcsb pdb:5E78|rcsb pdb:5JQ2|rcsb pdb:5JQU|rcsb pdb:5JQV|rcsb pdb:5JTD|interpro:IPR023173|rcsb pdb:5XA3|ensemblbacteria:AJI21949(transcript)|ensemblbacteria:BG04_163(gene)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070330"(aromatase activity)|rcsb pdb:3WSP|rcsb pdb:5OG9|rcsb pdb:5ZLH|rcsb pdb:4RSN|rcsb pdb:6K3Q|rcsb pdb:6L1A|rcsb pdb:6L1B|rcsb pdb:1SMJ|rcsb pdb:4DUE|rcsb pdb:4DUB|rcsb pdb:3NPL|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|rcsb pdb:4HGI|rcsb pdb:4DUF|rcsb pdb:1JPZ|interpro:IPR001128(Cytochrome P450)|rcsb pdb:3DGI|rcsb pdb:2J1M|rcsb pdb:4DUC|rcsb pdb:3HF2|interpro:IPR023206|rcsb pdb:4DQK|rcsb pdb:1ZO9|rcsb pdb:3CBD|rcsb pdb:2IJ2|rcsb pdb:2UWH|rcsb pdb:1ZO4|rcsb pdb:4HGH|rcsb pdb:1JME|rcsb pdb:2X7Y|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|rcsb pdb:3KX4|rcsb pdb:1BVY|rcsb pdb:1YQP|rcsb pdb:2BMH|rcsb pdb:4DU2|rcsb pdb:3EKF|rcsb pdb:2HPD|interpro:IPR017927|rcsb pdb:3EKD|rcsb pdb:1SMI|rcsb pdb:4DUA|rcsb pdb:4DTY|rcsb pdb:3KX3|rcsb pdb:3M4V|rcsb pdb:4DUD|rcsb pdb:4HGF|rcsb pdb:4DTZ|rcsb pdb:1BU7|interpro:IPR001094(Flavodoxin-like)|rcsb pdb:2X80|rcsb pdb:1YQO|interpro:IPR017972|rcsb pdb:1FAH|rcsb pdb:3KX5|rcsb pdb:4DQL|rcsb pdb:1P0X|rcsb pdb:1P0V|rcsb pdb:3PSX|rcsb pdb:2IJ3|rcsb pdb:3EKB|interpro:IPR017938|rcsb pdb:2IJ4|rcsb pdb:4HGG|rcsb pdb:4HGJ|rcsb pdb:1P0W|rcsb pdb:3BEN|rcsb pdb:2J4S|rcsb pdb:1ZOA|rcsb pdb:2NNB|rcsb pdb:4DTW|rcsb pdb:1FAG|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|rcsb pdb:5DYP|rcsb pdb:5DYZ|rcsb pdb:5E9Z|rcsb pdb:4KPA|rcsb pdb:4KPB|rcsb pdb:4H23|rcsb pdb:4H24|rcsb pdb:4KEW|rcsb pdb:4KEY|rcsb pdb:4KF0|rcsb pdb:4KF2|rcsb pdb:4O4P|refseq:WP_034650526.1|interpro:IPR029039|rcsb pdb:4WG2|rcsb pdb:5B2U|rcsb pdb:5B2V|rcsb pdb:5B2W|rcsb pdb:5B2X|rcsb pdb:5B2Y|interpro:IPR036396|rcsb pdb:5UCW|interpro:IPR039261|rcsb pdb:5ZIS|rcsb pdb:6H1O|rcsb pdb:6H1S|rcsb pdb:6IAO|rcsb pdb:6HN8|rcsb pdb:6LY4|rcsb pdb:6JLV|rcsb pdb:6JMH|rcsb pdb:6JMW|rcsb pdb:6JO1|rcsb pdb:6JS8|rcsb pdb:6JVC|rcsb pdb:6JZS|rcsb pdb:6K58|rcsb pdb:6K9S|rcsb pdb:6K24	-	-	comment:mint	figure legend:Table 1, Figure 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:2.44x10^-6 ~0.14(molar)	2019/05/29	2019/09/19	-	rogid:Oqu3y1hkk4FKpdRjfHQQkRz2qPQ1348623	-	false	-	mutation increasing interaction strength:88-88,83-83	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:9326"	uniprotkb:P14779	intact:EBI-21445036	intact:EBI-7701704|ensemblbacteria:AJI21949|intact:MINT-8313368|uniprotkb:A0A0B6AQ66|uniprotkb:Q9AE23	psi-mi:sulconazole nitrate(display_short)|psi-mi:"CHEBI:9326"(display_long)|intact:Sulconazole nitrate(synonym)	psi-mi:cpxb_bacmb(display_long)|uniprotkb:cyp102A1(gene name)|psi-mi:cyp102A1(display_short)|uniprotkb:"Cytochrome P450(BM-3)"(gene name synonym)|uniprotkb:cyp102(gene name synonym)|uniprotkb:Cytochrome P450BM-3(gene name synonym)|uniprotkb:Fatty acid monooxygenase(gene name synonym)|uniprotkb:Flavocytochrome P450 BM3(gene name synonym)|uniprotkb:BG04_163(orf name)	psi-mi:"MI:0966"(ultraviolet-visible spectroscopy)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1348623(bacmb)|taxid:1348623(bacmb)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21445042|imex:IM-27046-45	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:5XHJ|rcsb pdb:5E7Y|rcsb pdb:4ZF6|rcsb pdb:4ZF8|rcsb pdb:4ZFA|rcsb pdb:4ZFB|rcsb pdb:5E78|rcsb pdb:5JQ2|rcsb pdb:5JQU|rcsb pdb:5JQV|rcsb pdb:5JTD|interpro:IPR023173|rcsb pdb:5XA3|ensemblbacteria:AJI21949(transcript)|ensemblbacteria:BG04_163(gene)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070330"(aromatase activity)|rcsb pdb:3WSP|rcsb pdb:5OG9|rcsb pdb:5ZLH|rcsb pdb:4RSN|rcsb pdb:6K3Q|rcsb pdb:6L1A|rcsb pdb:6L1B|rcsb pdb:1SMJ|rcsb pdb:4DUE|rcsb pdb:4DUB|rcsb pdb:3NPL|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|rcsb pdb:4HGI|rcsb pdb:4DUF|rcsb pdb:1JPZ|interpro:IPR001128(Cytochrome P450)|rcsb pdb:3DGI|rcsb pdb:2J1M|rcsb pdb:4DUC|rcsb pdb:3HF2|interpro:IPR023206|rcsb pdb:4DQK|rcsb pdb:1ZO9|rcsb pdb:3CBD|rcsb pdb:2IJ2|rcsb pdb:2UWH|rcsb pdb:1ZO4|rcsb pdb:4HGH|rcsb pdb:1JME|rcsb pdb:2X7Y|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|rcsb pdb:3KX4|rcsb pdb:1BVY|rcsb pdb:1YQP|rcsb pdb:2BMH|rcsb pdb:4DU2|rcsb pdb:3EKF|rcsb pdb:2HPD|interpro:IPR017927|rcsb pdb:3EKD|rcsb pdb:1SMI|rcsb pdb:4DUA|rcsb pdb:4DTY|rcsb pdb:3KX3|rcsb pdb:3M4V|rcsb pdb:4DUD|rcsb pdb:4HGF|rcsb pdb:4DTZ|rcsb pdb:1BU7|interpro:IPR001094(Flavodoxin-like)|rcsb pdb:2X80|rcsb pdb:1YQO|interpro:IPR017972|rcsb pdb:1FAH|rcsb pdb:3KX5|rcsb pdb:4DQL|rcsb pdb:1P0X|rcsb pdb:1P0V|rcsb pdb:3PSX|rcsb pdb:2IJ3|rcsb pdb:3EKB|interpro:IPR017938|rcsb pdb:2IJ4|rcsb pdb:4HGG|rcsb pdb:4HGJ|rcsb pdb:1P0W|rcsb pdb:3BEN|rcsb pdb:2J4S|rcsb pdb:1ZOA|rcsb pdb:2NNB|rcsb pdb:4DTW|rcsb pdb:1FAG|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|rcsb pdb:5DYP|rcsb pdb:5DYZ|rcsb pdb:5E9Z|rcsb pdb:4KPA|rcsb pdb:4KPB|rcsb pdb:4H23|rcsb pdb:4H24|rcsb pdb:4KEW|rcsb pdb:4KEY|rcsb pdb:4KF0|rcsb pdb:4KF2|rcsb pdb:4O4P|refseq:WP_034650526.1|interpro:IPR029039|rcsb pdb:4WG2|rcsb pdb:5B2U|rcsb pdb:5B2V|rcsb pdb:5B2W|rcsb pdb:5B2X|rcsb pdb:5B2Y|interpro:IPR036396|rcsb pdb:5UCW|interpro:IPR039261|rcsb pdb:5ZIS|rcsb pdb:6H1O|rcsb pdb:6H1S|rcsb pdb:6IAO|rcsb pdb:6HN8|rcsb pdb:6LY4|rcsb pdb:6JLV|rcsb pdb:6JMH|rcsb pdb:6JMW|rcsb pdb:6JO1|rcsb pdb:6JS8|rcsb pdb:6JVC|rcsb pdb:6JZS|rcsb pdb:6K58|rcsb pdb:6K9S|rcsb pdb:6K24	-	-	comment:mint	figure legend:Table 1, Figure 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:8.93x10^-6 ~0.54(molar)	2019/05/29	2019/09/19	-	rogid:Oqu3y1hkk4FKpdRjfHQQkRz2qPQ1348623	-	false	-	mutation increasing interaction strength:83-83,88-88	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:9604"	uniprotkb:P14779	intact:EBI-21445074	intact:EBI-7701704|ensemblbacteria:AJI21949|intact:MINT-8313368|uniprotkb:A0A0B6AQ66|uniprotkb:Q9AE23	psi-mi:tioconazole(display_short)|psi-mi:"CHEBI:9604"(display_long)|intact:"(+-)-tioconazole"(synonym)|intact:"(+-)-1-(2,4-Dichloro-beta-((2-chloro-3-ethenyl)oxy)phenethyl)imidazole"(synonym)|intact:"(RS)-tioconazole"(synonym)|intact:"1-(2,4-Dichloro-(beta-(2-chloro-3-thenyl)oxy)phenethyl)imidazole"(synonym)|intact:rac-tioconazole(synonym)|intact:racemic tioconazole(synonym)|intact:tioconazol(synonym)|intact:tioconazole(synonym)|intact:tioconazolum(synonym)|intact:UK 20349(synonym)|intact:UK-20,349(synonym)|intact:Vagistat-1(synonym)|intact:"rac-1-{2-[(2-chloro-3-thienyl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole"(iupac name)	psi-mi:cpxb_bacmb(display_long)|uniprotkb:cyp102A1(gene name)|psi-mi:cyp102A1(display_short)|uniprotkb:"Cytochrome P450(BM-3)"(gene name synonym)|uniprotkb:cyp102(gene name synonym)|uniprotkb:Cytochrome P450BM-3(gene name synonym)|uniprotkb:Fatty acid monooxygenase(gene name synonym)|uniprotkb:Flavocytochrome P450 BM3(gene name synonym)|uniprotkb:BG04_163(orf name)	psi-mi:"MI:0966"(ultraviolet-visible spectroscopy)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1348623(bacmb)|taxid:1348623(bacmb)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21445089|imex:IM-27046-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:5XHJ|rcsb pdb:5E7Y|rcsb pdb:4ZF6|rcsb pdb:4ZF8|rcsb pdb:4ZFA|rcsb pdb:4ZFB|rcsb pdb:5E78|rcsb pdb:5JQ2|rcsb pdb:5JQU|rcsb pdb:5JQV|rcsb pdb:5JTD|interpro:IPR023173|rcsb pdb:5XA3|ensemblbacteria:AJI21949(transcript)|ensemblbacteria:BG04_163(gene)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070330"(aromatase activity)|rcsb pdb:3WSP|rcsb pdb:5OG9|rcsb pdb:5ZLH|rcsb pdb:4RSN|rcsb pdb:6K3Q|rcsb pdb:6L1A|rcsb pdb:6L1B|rcsb pdb:1SMJ|rcsb pdb:4DUE|rcsb pdb:4DUB|rcsb pdb:3NPL|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|rcsb pdb:4HGI|rcsb pdb:4DUF|rcsb pdb:1JPZ|interpro:IPR001128(Cytochrome P450)|rcsb pdb:3DGI|rcsb pdb:2J1M|rcsb pdb:4DUC|rcsb pdb:3HF2|interpro:IPR023206|rcsb pdb:4DQK|rcsb pdb:1ZO9|rcsb pdb:3CBD|rcsb pdb:2IJ2|rcsb pdb:2UWH|rcsb pdb:1ZO4|rcsb pdb:4HGH|rcsb pdb:1JME|rcsb pdb:2X7Y|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|rcsb pdb:3KX4|rcsb pdb:1BVY|rcsb pdb:1YQP|rcsb pdb:2BMH|rcsb pdb:4DU2|rcsb pdb:3EKF|rcsb pdb:2HPD|interpro:IPR017927|rcsb pdb:3EKD|rcsb pdb:1SMI|rcsb pdb:4DUA|rcsb pdb:4DTY|rcsb pdb:3KX3|rcsb pdb:3M4V|rcsb pdb:4DUD|rcsb pdb:4HGF|rcsb pdb:4DTZ|rcsb pdb:1BU7|interpro:IPR001094(Flavodoxin-like)|rcsb pdb:2X80|rcsb pdb:1YQO|interpro:IPR017972|rcsb pdb:1FAH|rcsb pdb:3KX5|rcsb pdb:4DQL|rcsb pdb:1P0X|rcsb pdb:1P0V|rcsb pdb:3PSX|rcsb pdb:2IJ3|rcsb pdb:3EKB|interpro:IPR017938|rcsb pdb:2IJ4|rcsb pdb:4HGG|rcsb pdb:4HGJ|rcsb pdb:1P0W|rcsb pdb:3BEN|rcsb pdb:2J4S|rcsb pdb:1ZOA|rcsb pdb:2NNB|rcsb pdb:4DTW|rcsb pdb:1FAG|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|rcsb pdb:5DYP|rcsb pdb:5DYZ|rcsb pdb:5E9Z|rcsb pdb:4KPA|rcsb pdb:4KPB|rcsb pdb:4H23|rcsb pdb:4H24|rcsb pdb:4KEW|rcsb pdb:4KEY|rcsb pdb:4KF0|rcsb pdb:4KF2|rcsb pdb:4O4P|refseq:WP_034650526.1|interpro:IPR029039|rcsb pdb:4WG2|rcsb pdb:5B2U|rcsb pdb:5B2V|rcsb pdb:5B2W|rcsb pdb:5B2X|rcsb pdb:5B2Y|interpro:IPR036396|rcsb pdb:5UCW|interpro:IPR039261|rcsb pdb:5ZIS|rcsb pdb:6H1O|rcsb pdb:6H1S|rcsb pdb:6IAO|rcsb pdb:6HN8|rcsb pdb:6LY4|rcsb pdb:6JLV|rcsb pdb:6JMH|rcsb pdb:6JMW|rcsb pdb:6JO1|rcsb pdb:6JS8|rcsb pdb:6JVC|rcsb pdb:6JZS|rcsb pdb:6K58|rcsb pdb:6K9S|rcsb pdb:6K24	-	-	comment:mint	figure legend:Table 1, Figure 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:24.5x10^-6 ~1.1(molar)	2019/05/29	2019/09/19	-	rogid:Oqu3y1hkk4FKpdRjfHQQkRz2qPQ1348623	-	false	-	mutation increasing interaction strength:83-83,88-88	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:46081"	uniprotkb:P14779	intact:EBI-21444880|chebi:"CHEBI:46079"|chebi:"CHEBI:5099"	intact:EBI-7701704|ensemblbacteria:AJI21949|intact:MINT-8313368|uniprotkb:A0A0B6AQ66|uniprotkb:Q9AE23	psi-mi:fluconazole(display_short)|psi-mi:"CHEBI:46081"(display_long)|intact:"2,4-difluoro-alpha,alpha-bis(1H-1,2,4-triazol-1-ylmethyl)benzyl alcohol"(synonym)|intact:"2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL"(synonym)|intact:Biozole(synonym)|intact:Diflucan(synonym)|intact:Elazor(synonym)|intact:fluconazol(synonym)|intact:fluconazole(synonym)|intact:fluconazolum(synonym)|intact:Triflucan(synonym)|intact:"2-(2,4-difluorophenyl)-1,3-bis-(1H-1,2,4-triazol-1-yl)propan-2-ol"(iupac name)	psi-mi:cpxb_bacmb(display_long)|uniprotkb:cyp102A1(gene name)|psi-mi:cyp102A1(display_short)|uniprotkb:"Cytochrome P450(BM-3)"(gene name synonym)|uniprotkb:cyp102(gene name synonym)|uniprotkb:Cytochrome P450BM-3(gene name synonym)|uniprotkb:Fatty acid monooxygenase(gene name synonym)|uniprotkb:Flavocytochrome P450 BM3(gene name synonym)|uniprotkb:BG04_163(orf name)	psi-mi:"MI:0966"(ultraviolet-visible spectroscopy)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1348623(bacmb)|taxid:1348623(bacmb)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21445722|imex:IM-27046-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:5XHJ|rcsb pdb:5E7Y|rcsb pdb:4ZF6|rcsb pdb:4ZF8|rcsb pdb:4ZFA|rcsb pdb:4ZFB|rcsb pdb:5E78|rcsb pdb:5JQ2|rcsb pdb:5JQU|rcsb pdb:5JQV|rcsb pdb:5JTD|interpro:IPR023173|rcsb pdb:5XA3|ensemblbacteria:AJI21949(transcript)|ensemblbacteria:BG04_163(gene)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070330"(aromatase activity)|rcsb pdb:3WSP|rcsb pdb:5OG9|rcsb pdb:5ZLH|rcsb pdb:4RSN|rcsb pdb:6K3Q|rcsb pdb:6L1A|rcsb pdb:6L1B|rcsb pdb:1SMJ|rcsb pdb:4DUE|rcsb pdb:4DUB|rcsb pdb:3NPL|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|rcsb pdb:4HGI|rcsb pdb:4DUF|rcsb pdb:1JPZ|interpro:IPR001128(Cytochrome P450)|rcsb pdb:3DGI|rcsb pdb:2J1M|rcsb pdb:4DUC|rcsb pdb:3HF2|interpro:IPR023206|rcsb pdb:4DQK|rcsb pdb:1ZO9|rcsb pdb:3CBD|rcsb pdb:2IJ2|rcsb pdb:2UWH|rcsb pdb:1ZO4|rcsb pdb:4HGH|rcsb pdb:1JME|rcsb pdb:2X7Y|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|rcsb pdb:3KX4|rcsb pdb:1BVY|rcsb pdb:1YQP|rcsb pdb:2BMH|rcsb pdb:4DU2|rcsb pdb:3EKF|rcsb pdb:2HPD|interpro:IPR017927|rcsb pdb:3EKD|rcsb pdb:1SMI|rcsb pdb:4DUA|rcsb pdb:4DTY|rcsb pdb:3KX3|rcsb pdb:3M4V|rcsb pdb:4DUD|rcsb pdb:4HGF|rcsb pdb:4DTZ|rcsb pdb:1BU7|interpro:IPR001094(Flavodoxin-like)|rcsb pdb:2X80|rcsb pdb:1YQO|interpro:IPR017972|rcsb pdb:1FAH|rcsb pdb:3KX5|rcsb pdb:4DQL|rcsb pdb:1P0X|rcsb pdb:1P0V|rcsb pdb:3PSX|rcsb pdb:2IJ3|rcsb pdb:3EKB|interpro:IPR017938|rcsb pdb:2IJ4|rcsb pdb:4HGG|rcsb pdb:4HGJ|rcsb pdb:1P0W|rcsb pdb:3BEN|rcsb pdb:2J4S|rcsb pdb:1ZOA|rcsb pdb:2NNB|rcsb pdb:4DTW|rcsb pdb:1FAG|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|rcsb pdb:5DYP|rcsb pdb:5DYZ|rcsb pdb:5E9Z|rcsb pdb:4KPA|rcsb pdb:4KPB|rcsb pdb:4H23|rcsb pdb:4H24|rcsb pdb:4KEW|rcsb pdb:4KEY|rcsb pdb:4KF0|rcsb pdb:4KF2|rcsb pdb:4O4P|refseq:WP_034650526.1|interpro:IPR029039|rcsb pdb:4WG2|rcsb pdb:5B2U|rcsb pdb:5B2V|rcsb pdb:5B2W|rcsb pdb:5B2X|rcsb pdb:5B2Y|interpro:IPR036396|rcsb pdb:5UCW|interpro:IPR039261|rcsb pdb:5ZIS|rcsb pdb:6H1O|rcsb pdb:6H1S|rcsb pdb:6IAO|rcsb pdb:6HN8|rcsb pdb:6LY4|rcsb pdb:6JLV|rcsb pdb:6JMH|rcsb pdb:6JMW|rcsb pdb:6JO1|rcsb pdb:6JS8|rcsb pdb:6JVC|rcsb pdb:6JZS|rcsb pdb:6K58|rcsb pdb:6K9S|rcsb pdb:6K24	-	-	comment:mint	figure legend:Table 1, Figure 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/05/29	2019/09/19	-	rogid:Oqu3y1hkk4FKpdRjfHQQkRz2qPQ1348623	-	false	-	mutation causing an interaction:88-88,83-83	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:6076"	uniprotkb:P14779	intact:EBI-21445742	intact:EBI-7701704|ensemblbacteria:AJI21949|intact:MINT-8313368|uniprotkb:A0A0B6AQ66|uniprotkb:Q9AE23	psi-mi:itraconazole(display_short)|psi-mi:"CHEBI:6076"(display_long)|intact:Itraconazole(synonym)|intact:"Itrizole (TN)"(synonym)|intact:Oriconazole(synonym)|intact:"Sporanox (TN)"(synonym)|intact:"2-(butan-2-yl)-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-2,4-dihydro-3H-1,2,4-triazol-3-one"(iupac name)	psi-mi:cpxb_bacmb(display_long)|uniprotkb:cyp102A1(gene name)|psi-mi:cyp102A1(display_short)|uniprotkb:"Cytochrome P450(BM-3)"(gene name synonym)|uniprotkb:cyp102(gene name synonym)|uniprotkb:Cytochrome P450BM-3(gene name synonym)|uniprotkb:Fatty acid monooxygenase(gene name synonym)|uniprotkb:Flavocytochrome P450 BM3(gene name synonym)|uniprotkb:BG04_163(orf name)	psi-mi:"MI:0966"(ultraviolet-visible spectroscopy)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1348623(bacmb)|taxid:1348623(bacmb)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21445752|imex:IM-27046-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:5XHJ|rcsb pdb:5E7Y|rcsb pdb:4ZF6|rcsb pdb:4ZF8|rcsb pdb:4ZFA|rcsb pdb:4ZFB|rcsb pdb:5E78|rcsb pdb:5JQ2|rcsb pdb:5JQU|rcsb pdb:5JQV|rcsb pdb:5JTD|interpro:IPR023173|rcsb pdb:5XA3|ensemblbacteria:AJI21949(transcript)|ensemblbacteria:BG04_163(gene)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070330"(aromatase activity)|rcsb pdb:3WSP|rcsb pdb:5OG9|rcsb pdb:5ZLH|rcsb pdb:4RSN|rcsb pdb:6K3Q|rcsb pdb:6L1A|rcsb pdb:6L1B|rcsb pdb:1SMJ|rcsb pdb:4DUE|rcsb pdb:4DUB|rcsb pdb:3NPL|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|rcsb pdb:4HGI|rcsb pdb:4DUF|rcsb pdb:1JPZ|interpro:IPR001128(Cytochrome P450)|rcsb pdb:3DGI|rcsb pdb:2J1M|rcsb pdb:4DUC|rcsb pdb:3HF2|interpro:IPR023206|rcsb pdb:4DQK|rcsb pdb:1ZO9|rcsb pdb:3CBD|rcsb pdb:2IJ2|rcsb pdb:2UWH|rcsb pdb:1ZO4|rcsb pdb:4HGH|rcsb pdb:1JME|rcsb pdb:2X7Y|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|rcsb pdb:3KX4|rcsb pdb:1BVY|rcsb pdb:1YQP|rcsb pdb:2BMH|rcsb pdb:4DU2|rcsb pdb:3EKF|rcsb pdb:2HPD|interpro:IPR017927|rcsb pdb:3EKD|rcsb pdb:1SMI|rcsb pdb:4DUA|rcsb pdb:4DTY|rcsb pdb:3KX3|rcsb pdb:3M4V|rcsb pdb:4DUD|rcsb pdb:4HGF|rcsb pdb:4DTZ|rcsb pdb:1BU7|interpro:IPR001094(Flavodoxin-like)|rcsb pdb:2X80|rcsb pdb:1YQO|interpro:IPR017972|rcsb pdb:1FAH|rcsb pdb:3KX5|rcsb pdb:4DQL|rcsb pdb:1P0X|rcsb pdb:1P0V|rcsb pdb:3PSX|rcsb pdb:2IJ3|rcsb pdb:3EKB|interpro:IPR017938|rcsb pdb:2IJ4|rcsb pdb:4HGG|rcsb pdb:4HGJ|rcsb pdb:1P0W|rcsb pdb:3BEN|rcsb pdb:2J4S|rcsb pdb:1ZOA|rcsb pdb:2NNB|rcsb pdb:4DTW|rcsb pdb:1FAG|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|rcsb pdb:5DYP|rcsb pdb:5DYZ|rcsb pdb:5E9Z|rcsb pdb:4KPA|rcsb pdb:4KPB|rcsb pdb:4H23|rcsb pdb:4H24|rcsb pdb:4KEW|rcsb pdb:4KEY|rcsb pdb:4KF0|rcsb pdb:4KF2|rcsb pdb:4O4P|refseq:WP_034650526.1|interpro:IPR029039|rcsb pdb:4WG2|rcsb pdb:5B2U|rcsb pdb:5B2V|rcsb pdb:5B2W|rcsb pdb:5B2X|rcsb pdb:5B2Y|interpro:IPR036396|rcsb pdb:5UCW|interpro:IPR039261|rcsb pdb:5ZIS|rcsb pdb:6H1O|rcsb pdb:6H1S|rcsb pdb:6IAO|rcsb pdb:6HN8|rcsb pdb:6LY4|rcsb pdb:6JLV|rcsb pdb:6JMH|rcsb pdb:6JMW|rcsb pdb:6JO1|rcsb pdb:6JS8|rcsb pdb:6JVC|rcsb pdb:6JZS|rcsb pdb:6K58|rcsb pdb:6K9S|rcsb pdb:6K24	-	-	comment:mint	figure legend:Table 1, Figure 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/05/29	2019/09/19	-	rogid:Oqu3y1hkk4FKpdRjfHQQkRz2qPQ1348623	-	false	-	mutation causing an interaction:83-83,88-88	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:64355"	uniprotkb:P14779	intact:EBI-21445797	intact:EBI-7701704|ensemblbacteria:AJI21949|intact:MINT-8313368|uniprotkb:A0A0B6AQ66|uniprotkb:Q9AE23	psi-mi:posaconazole(display_short)|psi-mi:"CHEBI:64355"(display_long)|intact:Noxafil(synonym)|intact:posaconazole(synonym)|intact:Sch 56592(synonym)|intact:SCH56592(synonym)|intact:Schering 56592(synonym)|intact:"2,5-anhydro-1,3,4-trideoxy-2-(2,4-difluorophenyl)-4-({4-[4-(4-{1-[(2S,3S)-2-hydroxypentan-3-yl]-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl}phenyl)piperazin-1-yl]phenoxy}methyl)-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol"(iupac name)	psi-mi:cpxb_bacmb(display_long)|uniprotkb:cyp102A1(gene name)|psi-mi:cyp102A1(display_short)|uniprotkb:"Cytochrome P450(BM-3)"(gene name synonym)|uniprotkb:cyp102(gene name synonym)|uniprotkb:Cytochrome P450BM-3(gene name synonym)|uniprotkb:Fatty acid monooxygenase(gene name synonym)|uniprotkb:Flavocytochrome P450 BM3(gene name synonym)|uniprotkb:BG04_163(orf name)	psi-mi:"MI:0966"(ultraviolet-visible spectroscopy)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1348623(bacmb)|taxid:1348623(bacmb)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21445808|imex:IM-27046-71	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:5XHJ|rcsb pdb:5E7Y|rcsb pdb:4ZF6|rcsb pdb:4ZF8|rcsb pdb:4ZFA|rcsb pdb:4ZFB|rcsb pdb:5E78|rcsb pdb:5JQ2|rcsb pdb:5JQU|rcsb pdb:5JQV|rcsb pdb:5JTD|interpro:IPR023173|rcsb pdb:5XA3|ensemblbacteria:AJI21949(transcript)|ensemblbacteria:BG04_163(gene)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070330"(aromatase activity)|rcsb pdb:3WSP|rcsb pdb:5OG9|rcsb pdb:5ZLH|rcsb pdb:4RSN|rcsb pdb:6K3Q|rcsb pdb:6L1A|rcsb pdb:6L1B|rcsb pdb:1SMJ|rcsb pdb:4DUE|rcsb pdb:4DUB|rcsb pdb:3NPL|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|rcsb pdb:4HGI|rcsb pdb:4DUF|rcsb pdb:1JPZ|interpro:IPR001128(Cytochrome P450)|rcsb pdb:3DGI|rcsb pdb:2J1M|rcsb pdb:4DUC|rcsb pdb:3HF2|interpro:IPR023206|rcsb pdb:4DQK|rcsb pdb:1ZO9|rcsb pdb:3CBD|rcsb pdb:2IJ2|rcsb pdb:2UWH|rcsb pdb:1ZO4|rcsb pdb:4HGH|rcsb pdb:1JME|rcsb pdb:2X7Y|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|rcsb pdb:3KX4|rcsb pdb:1BVY|rcsb pdb:1YQP|rcsb pdb:2BMH|rcsb pdb:4DU2|rcsb pdb:3EKF|rcsb pdb:2HPD|interpro:IPR017927|rcsb pdb:3EKD|rcsb pdb:1SMI|rcsb pdb:4DUA|rcsb pdb:4DTY|rcsb pdb:3KX3|rcsb pdb:3M4V|rcsb pdb:4DUD|rcsb pdb:4HGF|rcsb pdb:4DTZ|rcsb pdb:1BU7|interpro:IPR001094(Flavodoxin-like)|rcsb pdb:2X80|rcsb pdb:1YQO|interpro:IPR017972|rcsb pdb:1FAH|rcsb pdb:3KX5|rcsb pdb:4DQL|rcsb pdb:1P0X|rcsb pdb:1P0V|rcsb pdb:3PSX|rcsb pdb:2IJ3|rcsb pdb:3EKB|interpro:IPR017938|rcsb pdb:2IJ4|rcsb pdb:4HGG|rcsb pdb:4HGJ|rcsb pdb:1P0W|rcsb pdb:3BEN|rcsb pdb:2J4S|rcsb pdb:1ZOA|rcsb pdb:2NNB|rcsb pdb:4DTW|rcsb pdb:1FAG|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|rcsb pdb:5DYP|rcsb pdb:5DYZ|rcsb pdb:5E9Z|rcsb pdb:4KPA|rcsb pdb:4KPB|rcsb pdb:4H23|rcsb pdb:4H24|rcsb pdb:4KEW|rcsb pdb:4KEY|rcsb pdb:4KF0|rcsb pdb:4KF2|rcsb pdb:4O4P|refseq:WP_034650526.1|interpro:IPR029039|rcsb pdb:4WG2|rcsb pdb:5B2U|rcsb pdb:5B2V|rcsb pdb:5B2W|rcsb pdb:5B2X|rcsb pdb:5B2Y|interpro:IPR036396|rcsb pdb:5UCW|interpro:IPR039261|rcsb pdb:5ZIS|rcsb pdb:6H1O|rcsb pdb:6H1S|rcsb pdb:6IAO|rcsb pdb:6HN8|rcsb pdb:6LY4|rcsb pdb:6JLV|rcsb pdb:6JMH|rcsb pdb:6JMW|rcsb pdb:6JO1|rcsb pdb:6JS8|rcsb pdb:6JVC|rcsb pdb:6JZS|rcsb pdb:6K58|rcsb pdb:6K9S|rcsb pdb:6K24	-	-	comment:mint	figure legend:Table 1, Figure 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/05/29	2019/09/19	-	rogid:Oqu3y1hkk4FKpdRjfHQQkRz2qPQ1348623	-	false	-	mutation causing an interaction:83-83,88-88	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:143825"	uniprotkb:P14779	intact:EBI-21445816	intact:EBI-7701704|ensemblbacteria:AJI21949|intact:MINT-8313368|uniprotkb:A0A0B6AQ66|uniprotkb:Q9AE23	psi-mi:ravuconazole(display_short)|psi-mi:"CHEBI:143825"(display_long)	psi-mi:cpxb_bacmb(display_long)|uniprotkb:cyp102A1(gene name)|psi-mi:cyp102A1(display_short)|uniprotkb:"Cytochrome P450(BM-3)"(gene name synonym)|uniprotkb:cyp102(gene name synonym)|uniprotkb:Cytochrome P450BM-3(gene name synonym)|uniprotkb:Fatty acid monooxygenase(gene name synonym)|uniprotkb:Flavocytochrome P450 BM3(gene name synonym)|uniprotkb:BG04_163(orf name)	psi-mi:"MI:0966"(ultraviolet-visible spectroscopy)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1348623(bacmb)|taxid:1348623(bacmb)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21445818|imex:IM-27046-51	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:5XHJ|rcsb pdb:5E7Y|rcsb pdb:4ZF6|rcsb pdb:4ZF8|rcsb pdb:4ZFA|rcsb pdb:4ZFB|rcsb pdb:5E78|rcsb pdb:5JQ2|rcsb pdb:5JQU|rcsb pdb:5JQV|rcsb pdb:5JTD|interpro:IPR023173|rcsb pdb:5XA3|ensemblbacteria:AJI21949(transcript)|ensemblbacteria:BG04_163(gene)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070330"(aromatase activity)|rcsb pdb:3WSP|rcsb pdb:5OG9|rcsb pdb:5ZLH|rcsb pdb:4RSN|rcsb pdb:6K3Q|rcsb pdb:6L1A|rcsb pdb:6L1B|rcsb pdb:1SMJ|rcsb pdb:4DUE|rcsb pdb:4DUB|rcsb pdb:3NPL|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|rcsb pdb:4HGI|rcsb pdb:4DUF|rcsb pdb:1JPZ|interpro:IPR001128(Cytochrome P450)|rcsb pdb:3DGI|rcsb pdb:2J1M|rcsb pdb:4DUC|rcsb pdb:3HF2|interpro:IPR023206|rcsb pdb:4DQK|rcsb pdb:1ZO9|rcsb pdb:3CBD|rcsb pdb:2IJ2|rcsb pdb:2UWH|rcsb pdb:1ZO4|rcsb pdb:4HGH|rcsb pdb:1JME|rcsb pdb:2X7Y|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|rcsb pdb:3KX4|rcsb pdb:1BVY|rcsb pdb:1YQP|rcsb pdb:2BMH|rcsb pdb:4DU2|rcsb pdb:3EKF|rcsb pdb:2HPD|interpro:IPR017927|rcsb pdb:3EKD|rcsb pdb:1SMI|rcsb pdb:4DUA|rcsb pdb:4DTY|rcsb pdb:3KX3|rcsb pdb:3M4V|rcsb pdb:4DUD|rcsb pdb:4HGF|rcsb pdb:4DTZ|rcsb pdb:1BU7|interpro:IPR001094(Flavodoxin-like)|rcsb pdb:2X80|rcsb pdb:1YQO|interpro:IPR017972|rcsb pdb:1FAH|rcsb pdb:3KX5|rcsb pdb:4DQL|rcsb pdb:1P0X|rcsb pdb:1P0V|rcsb pdb:3PSX|rcsb pdb:2IJ3|rcsb pdb:3EKB|interpro:IPR017938|rcsb pdb:2IJ4|rcsb pdb:4HGG|rcsb pdb:4HGJ|rcsb pdb:1P0W|rcsb pdb:3BEN|rcsb pdb:2J4S|rcsb pdb:1ZOA|rcsb pdb:2NNB|rcsb pdb:4DTW|rcsb pdb:1FAG|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|rcsb pdb:5DYP|rcsb pdb:5DYZ|rcsb pdb:5E9Z|rcsb pdb:4KPA|rcsb pdb:4KPB|rcsb pdb:4H23|rcsb pdb:4H24|rcsb pdb:4KEW|rcsb pdb:4KEY|rcsb pdb:4KF0|rcsb pdb:4KF2|rcsb pdb:4O4P|refseq:WP_034650526.1|interpro:IPR029039|rcsb pdb:4WG2|rcsb pdb:5B2U|rcsb pdb:5B2V|rcsb pdb:5B2W|rcsb pdb:5B2X|rcsb pdb:5B2Y|interpro:IPR036396|rcsb pdb:5UCW|interpro:IPR039261|rcsb pdb:5ZIS|rcsb pdb:6H1O|rcsb pdb:6H1S|rcsb pdb:6IAO|rcsb pdb:6HN8|rcsb pdb:6LY4|rcsb pdb:6JLV|rcsb pdb:6JMH|rcsb pdb:6JMW|rcsb pdb:6JO1|rcsb pdb:6JS8|rcsb pdb:6JVC|rcsb pdb:6JZS|rcsb pdb:6K58|rcsb pdb:6K9S|rcsb pdb:6K24	-	-	comment:mint	figure legend:Table 1, Figure 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/05/29	2019/09/19	-	rogid:Oqu3y1hkk4FKpdRjfHQQkRz2qPQ1348623	-	false	-	mutation causing an interaction:83-83,88-88	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:10023"	uniprotkb:P14779	intact:EBI-21445844|chebi:"CHEBI:127308"	intact:EBI-7701704|ensemblbacteria:AJI21949|intact:MINT-8313368|uniprotkb:A0A0B6AQ66|uniprotkb:Q9AE23	psi-mi:voriconazole(display_short)|psi-mi:"CHEBI:10023"(display_long)|intact:"(alphaR,betaS)-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol"(synonym)|intact:"(R-(R*,S*))-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol"(synonym)|intact:VCZ(synonym)|intact:Vfend(synonym)|intact:voriconazol(synonym)|intact:voriconazole(synonym)|intact:voriconazolum(synonym)|intact:"(2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol"(iupac name)	psi-mi:cpxb_bacmb(display_long)|uniprotkb:cyp102A1(gene name)|psi-mi:cyp102A1(display_short)|uniprotkb:"Cytochrome P450(BM-3)"(gene name synonym)|uniprotkb:cyp102(gene name synonym)|uniprotkb:Cytochrome P450BM-3(gene name synonym)|uniprotkb:Fatty acid monooxygenase(gene name synonym)|uniprotkb:Flavocytochrome P450 BM3(gene name synonym)|uniprotkb:BG04_163(orf name)	psi-mi:"MI:0966"(ultraviolet-visible spectroscopy)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1348623(bacmb)|taxid:1348623(bacmb)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21445858|imex:IM-27046-73	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:5XHJ|rcsb pdb:5E7Y|rcsb pdb:4ZF6|rcsb pdb:4ZF8|rcsb pdb:4ZFA|rcsb pdb:4ZFB|rcsb pdb:5E78|rcsb pdb:5JQ2|rcsb pdb:5JQU|rcsb pdb:5JQV|rcsb pdb:5JTD|interpro:IPR023173|rcsb pdb:5XA3|ensemblbacteria:AJI21949(transcript)|ensemblbacteria:BG04_163(gene)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070330"(aromatase activity)|rcsb pdb:3WSP|rcsb pdb:5OG9|rcsb pdb:5ZLH|rcsb pdb:4RSN|rcsb pdb:6K3Q|rcsb pdb:6L1A|rcsb pdb:6L1B|rcsb pdb:1SMJ|rcsb pdb:4DUE|rcsb pdb:4DUB|rcsb pdb:3NPL|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|rcsb pdb:4HGI|rcsb pdb:4DUF|rcsb pdb:1JPZ|interpro:IPR001128(Cytochrome P450)|rcsb pdb:3DGI|rcsb pdb:2J1M|rcsb pdb:4DUC|rcsb pdb:3HF2|interpro:IPR023206|rcsb pdb:4DQK|rcsb pdb:1ZO9|rcsb pdb:3CBD|rcsb pdb:2IJ2|rcsb pdb:2UWH|rcsb pdb:1ZO4|rcsb pdb:4HGH|rcsb pdb:1JME|rcsb pdb:2X7Y|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|rcsb pdb:3KX4|rcsb pdb:1BVY|rcsb pdb:1YQP|rcsb pdb:2BMH|rcsb pdb:4DU2|rcsb pdb:3EKF|rcsb pdb:2HPD|interpro:IPR017927|rcsb pdb:3EKD|rcsb pdb:1SMI|rcsb pdb:4DUA|rcsb pdb:4DTY|rcsb pdb:3KX3|rcsb pdb:3M4V|rcsb pdb:4DUD|rcsb pdb:4HGF|rcsb pdb:4DTZ|rcsb pdb:1BU7|interpro:IPR001094(Flavodoxin-like)|rcsb pdb:2X80|rcsb pdb:1YQO|interpro:IPR017972|rcsb pdb:1FAH|rcsb pdb:3KX5|rcsb pdb:4DQL|rcsb pdb:1P0X|rcsb pdb:1P0V|rcsb pdb:3PSX|rcsb pdb:2IJ3|rcsb pdb:3EKB|interpro:IPR017938|rcsb pdb:2IJ4|rcsb pdb:4HGG|rcsb pdb:4HGJ|rcsb pdb:1P0W|rcsb pdb:3BEN|rcsb pdb:2J4S|rcsb pdb:1ZOA|rcsb pdb:2NNB|rcsb pdb:4DTW|rcsb pdb:1FAG|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|rcsb pdb:5DYP|rcsb pdb:5DYZ|rcsb pdb:5E9Z|rcsb pdb:4KPA|rcsb pdb:4KPB|rcsb pdb:4H23|rcsb pdb:4H24|rcsb pdb:4KEW|rcsb pdb:4KEY|rcsb pdb:4KF0|rcsb pdb:4KF2|rcsb pdb:4O4P|refseq:WP_034650526.1|interpro:IPR029039|rcsb pdb:4WG2|rcsb pdb:5B2U|rcsb pdb:5B2V|rcsb pdb:5B2W|rcsb pdb:5B2X|rcsb pdb:5B2Y|interpro:IPR036396|rcsb pdb:5UCW|interpro:IPR039261|rcsb pdb:5ZIS|rcsb pdb:6H1O|rcsb pdb:6H1S|rcsb pdb:6IAO|rcsb pdb:6HN8|rcsb pdb:6LY4|rcsb pdb:6JLV|rcsb pdb:6JMH|rcsb pdb:6JMW|rcsb pdb:6JO1|rcsb pdb:6JS8|rcsb pdb:6JVC|rcsb pdb:6JZS|rcsb pdb:6K58|rcsb pdb:6K9S|rcsb pdb:6K24	-	-	comment:mint	figure legend:Table 1, Figure 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/05/29	2019/09/19	-	rogid:Oqu3y1hkk4FKpdRjfHQQkRz2qPQ1348623	-	false	-	mutation causing an interaction:83-83,88-88	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:31286"	uniprotkb:P14779	intact:EBI-21444780	intact:EBI-7701704|ensemblbacteria:AJI21949|intact:MINT-8313368|uniprotkb:A0A0B6AQ66|uniprotkb:Q9AE23	psi-mi:bifonazole(display_short)|psi-mi:"CHEBI:31286"(display_long)|intact:"(+-)-bifonazole"(synonym)|intact:"(+-)-1-(p,alpha-Diphenylbenzyl)imidazole"(synonym)|intact:"(+-)1-([1,1'-Biphenyl]-4-ylphenylmethyl)-1H-imidazole"(synonym)|intact:"(RS)-bifonazole"(synonym)|intact:"1-((4-Biphenylyl)phenylmethyl)-1H-imidazole"(synonym)|intact:"1-(alpha-(4-Biphenylyl)benzyl)imidazole"(synonym)|intact:bifonazol(synonym)|intact:bifonazole(synonym)|intact:bifonazolum(synonym)|intact:Mycospor(synonym)|intact:rac-bifonazole(synonym)|intact:racemic bifonazole(synonym)|intact:"rac-1-[biphenyl-4-yl(phenyl)methyl]-1H-imidazole"(iupac name)	psi-mi:cpxb_bacmb(display_long)|uniprotkb:cyp102A1(gene name)|psi-mi:cyp102A1(display_short)|uniprotkb:"Cytochrome P450(BM-3)"(gene name synonym)|uniprotkb:cyp102(gene name synonym)|uniprotkb:Cytochrome P450BM-3(gene name synonym)|uniprotkb:Fatty acid monooxygenase(gene name synonym)|uniprotkb:Flavocytochrome P450 BM3(gene name synonym)|uniprotkb:BG04_163(orf name)	psi-mi:"MI:0042"(electron paramagnetic resonance)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1348623(bacmb)|taxid:1348623(bacmb)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21445138|imex:IM-27046-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:5XHJ|rcsb pdb:5E7Y|rcsb pdb:4ZF6|rcsb pdb:4ZF8|rcsb pdb:4ZFA|rcsb pdb:4ZFB|rcsb pdb:5E78|rcsb pdb:5JQ2|rcsb pdb:5JQU|rcsb pdb:5JQV|rcsb pdb:5JTD|interpro:IPR023173|rcsb pdb:5XA3|ensemblbacteria:AJI21949(transcript)|ensemblbacteria:BG04_163(gene)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070330"(aromatase activity)|rcsb pdb:3WSP|rcsb pdb:5OG9|rcsb pdb:5ZLH|rcsb pdb:4RSN|rcsb pdb:6K3Q|rcsb pdb:6L1A|rcsb pdb:6L1B|rcsb pdb:1SMJ|rcsb pdb:4DUE|rcsb pdb:4DUB|rcsb pdb:3NPL|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|rcsb pdb:4HGI|rcsb pdb:4DUF|rcsb pdb:1JPZ|interpro:IPR001128(Cytochrome P450)|rcsb pdb:3DGI|rcsb pdb:2J1M|rcsb pdb:4DUC|rcsb pdb:3HF2|interpro:IPR023206|rcsb pdb:4DQK|rcsb pdb:1ZO9|rcsb pdb:3CBD|rcsb pdb:2IJ2|rcsb pdb:2UWH|rcsb pdb:1ZO4|rcsb pdb:4HGH|rcsb pdb:1JME|rcsb pdb:2X7Y|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|rcsb pdb:3KX4|rcsb pdb:1BVY|rcsb pdb:1YQP|rcsb pdb:2BMH|rcsb pdb:4DU2|rcsb pdb:3EKF|rcsb pdb:2HPD|interpro:IPR017927|rcsb pdb:3EKD|rcsb pdb:1SMI|rcsb pdb:4DUA|rcsb pdb:4DTY|rcsb pdb:3KX3|rcsb pdb:3M4V|rcsb pdb:4DUD|rcsb pdb:4HGF|rcsb pdb:4DTZ|rcsb pdb:1BU7|interpro:IPR001094(Flavodoxin-like)|rcsb pdb:2X80|rcsb pdb:1YQO|interpro:IPR017972|rcsb pdb:1FAH|rcsb pdb:3KX5|rcsb pdb:4DQL|rcsb pdb:1P0X|rcsb pdb:1P0V|rcsb pdb:3PSX|rcsb pdb:2IJ3|rcsb pdb:3EKB|interpro:IPR017938|rcsb pdb:2IJ4|rcsb pdb:4HGG|rcsb pdb:4HGJ|rcsb pdb:1P0W|rcsb pdb:3BEN|rcsb pdb:2J4S|rcsb pdb:1ZOA|rcsb pdb:2NNB|rcsb pdb:4DTW|rcsb pdb:1FAG|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|rcsb pdb:5DYP|rcsb pdb:5DYZ|rcsb pdb:5E9Z|rcsb pdb:4KPA|rcsb pdb:4KPB|rcsb pdb:4H23|rcsb pdb:4H24|rcsb pdb:4KEW|rcsb pdb:4KEY|rcsb pdb:4KF0|rcsb pdb:4KF2|rcsb pdb:4O4P|refseq:WP_034650526.1|interpro:IPR029039|rcsb pdb:4WG2|rcsb pdb:5B2U|rcsb pdb:5B2V|rcsb pdb:5B2W|rcsb pdb:5B2X|rcsb pdb:5B2Y|interpro:IPR036396|rcsb pdb:5UCW|interpro:IPR039261|rcsb pdb:5ZIS|rcsb pdb:6H1O|rcsb pdb:6H1S|rcsb pdb:6IAO|rcsb pdb:6HN8|rcsb pdb:6LY4|rcsb pdb:6JLV|rcsb pdb:6JMH|rcsb pdb:6JMW|rcsb pdb:6JO1|rcsb pdb:6JS8|rcsb pdb:6JVC|rcsb pdb:6JZS|rcsb pdb:6K58|rcsb pdb:6K9S|rcsb pdb:6K24	-	-	comment:mint	figure legend:Figure 3, Table S2, S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/05/29	2019/09/19	-	rogid:Oqu3y1hkk4FKpdRjfHQQkRz2qPQ1348623	-	false	-	mutation with no effect:88-88,83-83	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:3241"	uniprotkb:P14779	intact:EBI-21444804	intact:EBI-7701704|ensemblbacteria:AJI21949|intact:MINT-8313368|uniprotkb:A0A0B6AQ66|uniprotkb:Q9AE23	psi-mi:butoconazole nitrate(display_short)|psi-mi:"CHEBI:3241"(display_long)|intact:"(+-)-1-(4-(4-chlorophenyl)-2-((2,6-dichlorophenyl)thio)butyl)-1H-imidazole mononitrate"(synonym)|intact:"(+-)-1-(4-(p-chlorophenyl)-2-((2,6-dichlorophenyl)thio)butyl)imidazole mononitrate"(synonym)|intact:Butoconazole nitrate(synonym)|intact:nitrato de butoconazol(synonym)|intact:"1-{4-(4-chlorophenyl)-2-[(2,6-dichlorophenyl)sulfanyl]butyl}-1H-imidazole nitrate"(iupac name)	psi-mi:cpxb_bacmb(display_long)|uniprotkb:cyp102A1(gene name)|psi-mi:cyp102A1(display_short)|uniprotkb:"Cytochrome P450(BM-3)"(gene name synonym)|uniprotkb:cyp102(gene name synonym)|uniprotkb:Cytochrome P450BM-3(gene name synonym)|uniprotkb:Fatty acid monooxygenase(gene name synonym)|uniprotkb:Flavocytochrome P450 BM3(gene name synonym)|uniprotkb:BG04_163(orf name)	psi-mi:"MI:0042"(electron paramagnetic resonance)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1348623(bacmb)|taxid:1348623(bacmb)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21445557|imex:IM-27046-47	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:5XHJ|rcsb pdb:5E7Y|rcsb pdb:4ZF6|rcsb pdb:4ZF8|rcsb pdb:4ZFA|rcsb pdb:4ZFB|rcsb pdb:5E78|rcsb pdb:5JQ2|rcsb pdb:5JQU|rcsb pdb:5JQV|rcsb pdb:5JTD|interpro:IPR023173|rcsb pdb:5XA3|ensemblbacteria:AJI21949(transcript)|ensemblbacteria:BG04_163(gene)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070330"(aromatase activity)|rcsb pdb:3WSP|rcsb pdb:5OG9|rcsb pdb:5ZLH|rcsb pdb:4RSN|rcsb pdb:6K3Q|rcsb pdb:6L1A|rcsb pdb:6L1B|rcsb pdb:1SMJ|rcsb pdb:4DUE|rcsb pdb:4DUB|rcsb pdb:3NPL|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|rcsb pdb:4HGI|rcsb pdb:4DUF|rcsb pdb:1JPZ|interpro:IPR001128(Cytochrome P450)|rcsb pdb:3DGI|rcsb pdb:2J1M|rcsb pdb:4DUC|rcsb pdb:3HF2|interpro:IPR023206|rcsb pdb:4DQK|rcsb pdb:1ZO9|rcsb pdb:3CBD|rcsb pdb:2IJ2|rcsb pdb:2UWH|rcsb pdb:1ZO4|rcsb pdb:4HGH|rcsb pdb:1JME|rcsb pdb:2X7Y|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|rcsb pdb:3KX4|rcsb pdb:1BVY|rcsb pdb:1YQP|rcsb pdb:2BMH|rcsb pdb:4DU2|rcsb pdb:3EKF|rcsb pdb:2HPD|interpro:IPR017927|rcsb pdb:3EKD|rcsb pdb:1SMI|rcsb pdb:4DUA|rcsb pdb:4DTY|rcsb pdb:3KX3|rcsb pdb:3M4V|rcsb pdb:4DUD|rcsb pdb:4HGF|rcsb pdb:4DTZ|rcsb pdb:1BU7|interpro:IPR001094(Flavodoxin-like)|rcsb pdb:2X80|rcsb pdb:1YQO|interpro:IPR017972|rcsb pdb:1FAH|rcsb pdb:3KX5|rcsb pdb:4DQL|rcsb pdb:1P0X|rcsb pdb:1P0V|rcsb pdb:3PSX|rcsb pdb:2IJ3|rcsb pdb:3EKB|interpro:IPR017938|rcsb pdb:2IJ4|rcsb pdb:4HGG|rcsb pdb:4HGJ|rcsb pdb:1P0W|rcsb pdb:3BEN|rcsb pdb:2J4S|rcsb pdb:1ZOA|rcsb pdb:2NNB|rcsb pdb:4DTW|rcsb pdb:1FAG|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|rcsb pdb:5DYP|rcsb pdb:5DYZ|rcsb pdb:5E9Z|rcsb pdb:4KPA|rcsb pdb:4KPB|rcsb pdb:4H23|rcsb pdb:4H24|rcsb pdb:4KEW|rcsb pdb:4KEY|rcsb pdb:4KF0|rcsb pdb:4KF2|rcsb pdb:4O4P|refseq:WP_034650526.1|interpro:IPR029039|rcsb pdb:4WG2|rcsb pdb:5B2U|rcsb pdb:5B2V|rcsb pdb:5B2W|rcsb pdb:5B2X|rcsb pdb:5B2Y|interpro:IPR036396|rcsb pdb:5UCW|interpro:IPR039261|rcsb pdb:5ZIS|rcsb pdb:6H1O|rcsb pdb:6H1S|rcsb pdb:6IAO|rcsb pdb:6HN8|rcsb pdb:6LY4|rcsb pdb:6JLV|rcsb pdb:6JMH|rcsb pdb:6JMW|rcsb pdb:6JO1|rcsb pdb:6JS8|rcsb pdb:6JVC|rcsb pdb:6JZS|rcsb pdb:6K58|rcsb pdb:6K9S|rcsb pdb:6K24	-	-	comment:mint	figure legend:Table S2, S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/05/29	2019/09/19	-	rogid:Oqu3y1hkk4FKpdRjfHQQkRz2qPQ1348623	-	false	-	mutation with no effect:88-88,83-83	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:46081"	uniprotkb:P14779	intact:EBI-21444880|chebi:"CHEBI:46079"|chebi:"CHEBI:5099"	intact:EBI-7701704|ensemblbacteria:AJI21949|intact:MINT-8313368|uniprotkb:A0A0B6AQ66|uniprotkb:Q9AE23	psi-mi:fluconazole(display_short)|psi-mi:"CHEBI:46081"(display_long)|intact:"2,4-difluoro-alpha,alpha-bis(1H-1,2,4-triazol-1-ylmethyl)benzyl alcohol"(synonym)|intact:"2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL"(synonym)|intact:Biozole(synonym)|intact:Diflucan(synonym)|intact:Elazor(synonym)|intact:fluconazol(synonym)|intact:fluconazole(synonym)|intact:fluconazolum(synonym)|intact:Triflucan(synonym)|intact:"2-(2,4-difluorophenyl)-1,3-bis-(1H-1,2,4-triazol-1-yl)propan-2-ol"(iupac name)	psi-mi:cpxb_bacmb(display_long)|uniprotkb:cyp102A1(gene name)|psi-mi:cyp102A1(display_short)|uniprotkb:"Cytochrome P450(BM-3)"(gene name synonym)|uniprotkb:cyp102(gene name synonym)|uniprotkb:Cytochrome P450BM-3(gene name synonym)|uniprotkb:Fatty acid monooxygenase(gene name synonym)|uniprotkb:Flavocytochrome P450 BM3(gene name synonym)|uniprotkb:BG04_163(orf name)	psi-mi:"MI:0042"(electron paramagnetic resonance)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1348623(bacmb)|taxid:1348623(bacmb)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21445567|imex:IM-27046-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:5XHJ|rcsb pdb:5E7Y|rcsb pdb:4ZF6|rcsb pdb:4ZF8|rcsb pdb:4ZFA|rcsb pdb:4ZFB|rcsb pdb:5E78|rcsb pdb:5JQ2|rcsb pdb:5JQU|rcsb pdb:5JQV|rcsb pdb:5JTD|interpro:IPR023173|rcsb pdb:5XA3|ensemblbacteria:AJI21949(transcript)|ensemblbacteria:BG04_163(gene)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070330"(aromatase activity)|rcsb pdb:3WSP|rcsb pdb:5OG9|rcsb pdb:5ZLH|rcsb pdb:4RSN|rcsb pdb:6K3Q|rcsb pdb:6L1A|rcsb pdb:6L1B|rcsb pdb:1SMJ|rcsb pdb:4DUE|rcsb pdb:4DUB|rcsb pdb:3NPL|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|rcsb pdb:4HGI|rcsb pdb:4DUF|rcsb pdb:1JPZ|interpro:IPR001128(Cytochrome P450)|rcsb pdb:3DGI|rcsb pdb:2J1M|rcsb pdb:4DUC|rcsb pdb:3HF2|interpro:IPR023206|rcsb pdb:4DQK|rcsb pdb:1ZO9|rcsb pdb:3CBD|rcsb pdb:2IJ2|rcsb pdb:2UWH|rcsb pdb:1ZO4|rcsb pdb:4HGH|rcsb pdb:1JME|rcsb pdb:2X7Y|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|rcsb pdb:3KX4|rcsb pdb:1BVY|rcsb pdb:1YQP|rcsb pdb:2BMH|rcsb pdb:4DU2|rcsb pdb:3EKF|rcsb pdb:2HPD|interpro:IPR017927|rcsb pdb:3EKD|rcsb pdb:1SMI|rcsb pdb:4DUA|rcsb pdb:4DTY|rcsb pdb:3KX3|rcsb pdb:3M4V|rcsb pdb:4DUD|rcsb pdb:4HGF|rcsb pdb:4DTZ|rcsb pdb:1BU7|interpro:IPR001094(Flavodoxin-like)|rcsb pdb:2X80|rcsb pdb:1YQO|interpro:IPR017972|rcsb pdb:1FAH|rcsb pdb:3KX5|rcsb pdb:4DQL|rcsb pdb:1P0X|rcsb pdb:1P0V|rcsb pdb:3PSX|rcsb pdb:2IJ3|rcsb pdb:3EKB|interpro:IPR017938|rcsb pdb:2IJ4|rcsb pdb:4HGG|rcsb pdb:4HGJ|rcsb pdb:1P0W|rcsb pdb:3BEN|rcsb pdb:2J4S|rcsb pdb:1ZOA|rcsb pdb:2NNB|rcsb pdb:4DTW|rcsb pdb:1FAG|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|rcsb pdb:5DYP|rcsb pdb:5DYZ|rcsb pdb:5E9Z|rcsb pdb:4KPA|rcsb pdb:4KPB|rcsb pdb:4H23|rcsb pdb:4H24|rcsb pdb:4KEW|rcsb pdb:4KEY|rcsb pdb:4KF0|rcsb pdb:4KF2|rcsb pdb:4O4P|refseq:WP_034650526.1|interpro:IPR029039|rcsb pdb:4WG2|rcsb pdb:5B2U|rcsb pdb:5B2V|rcsb pdb:5B2W|rcsb pdb:5B2X|rcsb pdb:5B2Y|interpro:IPR036396|rcsb pdb:5UCW|interpro:IPR039261|rcsb pdb:5ZIS|rcsb pdb:6H1O|rcsb pdb:6H1S|rcsb pdb:6IAO|rcsb pdb:6HN8|rcsb pdb:6LY4|rcsb pdb:6JLV|rcsb pdb:6JMH|rcsb pdb:6JMW|rcsb pdb:6JO1|rcsb pdb:6JS8|rcsb pdb:6JVC|rcsb pdb:6JZS|rcsb pdb:6K58|rcsb pdb:6K9S|rcsb pdb:6K24	-	-	comment:mint	figure legend:Figure 3, Table S2, S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/05/29	2019/09/19	-	rogid:Oqu3y1hkk4FKpdRjfHQQkRz2qPQ1348623	-	false	-	mutation with no effect:83-83,88-88	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:83687"	uniprotkb:P14779	intact:EBI-21445017	intact:EBI-7701704|ensemblbacteria:AJI21949|intact:MINT-8313368|uniprotkb:A0A0B6AQ66|uniprotkb:Q9AE23	psi-mi:sertaconazole nitrate(display_short)|psi-mi:"CHEBI:83687"(display_long)|intact:"(+-)-sertaconazole nitrate"(synonym)|intact:"(RS)-sertaconazole nitrate"(synonym)|intact:Ertaczo(synonym)|intact:rac-sertaconazole nitrate(synonym)|intact:racemic sertaconazole nitrate(synonym)|intact:sertaconazole mononitrate(synonym)|intact:Zalain(synonym)|intact:"rac-1-{2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole nitrate"(iupac name)	psi-mi:cpxb_bacmb(display_long)|uniprotkb:cyp102A1(gene name)|psi-mi:cyp102A1(display_short)|uniprotkb:"Cytochrome P450(BM-3)"(gene name synonym)|uniprotkb:cyp102(gene name synonym)|uniprotkb:Cytochrome P450BM-3(gene name synonym)|uniprotkb:Fatty acid monooxygenase(gene name synonym)|uniprotkb:Flavocytochrome P450 BM3(gene name synonym)|uniprotkb:BG04_163(orf name)	psi-mi:"MI:0042"(electron paramagnetic resonance)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1348623(bacmb)|taxid:1348623(bacmb)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21445576|imex:IM-27046-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:5XHJ|rcsb pdb:5E7Y|rcsb pdb:4ZF6|rcsb pdb:4ZF8|rcsb pdb:4ZFA|rcsb pdb:4ZFB|rcsb pdb:5E78|rcsb pdb:5JQ2|rcsb pdb:5JQU|rcsb pdb:5JQV|rcsb pdb:5JTD|interpro:IPR023173|rcsb pdb:5XA3|ensemblbacteria:AJI21949(transcript)|ensemblbacteria:BG04_163(gene)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070330"(aromatase activity)|rcsb pdb:3WSP|rcsb pdb:5OG9|rcsb pdb:5ZLH|rcsb pdb:4RSN|rcsb pdb:6K3Q|rcsb pdb:6L1A|rcsb pdb:6L1B|rcsb pdb:1SMJ|rcsb pdb:4DUE|rcsb pdb:4DUB|rcsb pdb:3NPL|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|rcsb pdb:4HGI|rcsb pdb:4DUF|rcsb pdb:1JPZ|interpro:IPR001128(Cytochrome P450)|rcsb pdb:3DGI|rcsb pdb:2J1M|rcsb pdb:4DUC|rcsb pdb:3HF2|interpro:IPR023206|rcsb pdb:4DQK|rcsb pdb:1ZO9|rcsb pdb:3CBD|rcsb pdb:2IJ2|rcsb pdb:2UWH|rcsb pdb:1ZO4|rcsb pdb:4HGH|rcsb pdb:1JME|rcsb pdb:2X7Y|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|rcsb pdb:3KX4|rcsb pdb:1BVY|rcsb pdb:1YQP|rcsb pdb:2BMH|rcsb pdb:4DU2|rcsb pdb:3EKF|rcsb pdb:2HPD|interpro:IPR017927|rcsb pdb:3EKD|rcsb pdb:1SMI|rcsb pdb:4DUA|rcsb pdb:4DTY|rcsb pdb:3KX3|rcsb pdb:3M4V|rcsb pdb:4DUD|rcsb pdb:4HGF|rcsb pdb:4DTZ|rcsb pdb:1BU7|interpro:IPR001094(Flavodoxin-like)|rcsb pdb:2X80|rcsb pdb:1YQO|interpro:IPR017972|rcsb pdb:1FAH|rcsb pdb:3KX5|rcsb pdb:4DQL|rcsb pdb:1P0X|rcsb pdb:1P0V|rcsb pdb:3PSX|rcsb pdb:2IJ3|rcsb pdb:3EKB|interpro:IPR017938|rcsb pdb:2IJ4|rcsb pdb:4HGG|rcsb pdb:4HGJ|rcsb pdb:1P0W|rcsb pdb:3BEN|rcsb pdb:2J4S|rcsb pdb:1ZOA|rcsb pdb:2NNB|rcsb pdb:4DTW|rcsb pdb:1FAG|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|rcsb pdb:5DYP|rcsb pdb:5DYZ|rcsb pdb:5E9Z|rcsb pdb:4KPA|rcsb pdb:4KPB|rcsb pdb:4H23|rcsb pdb:4H24|rcsb pdb:4KEW|rcsb pdb:4KEY|rcsb pdb:4KF0|rcsb pdb:4KF2|rcsb pdb:4O4P|refseq:WP_034650526.1|interpro:IPR029039|rcsb pdb:4WG2|rcsb pdb:5B2U|rcsb pdb:5B2V|rcsb pdb:5B2W|rcsb pdb:5B2X|rcsb pdb:5B2Y|interpro:IPR036396|rcsb pdb:5UCW|interpro:IPR039261|rcsb pdb:5ZIS|rcsb pdb:6H1O|rcsb pdb:6H1S|rcsb pdb:6IAO|rcsb pdb:6HN8|rcsb pdb:6LY4|rcsb pdb:6JLV|rcsb pdb:6JMH|rcsb pdb:6JMW|rcsb pdb:6JO1|rcsb pdb:6JS8|rcsb pdb:6JVC|rcsb pdb:6JZS|rcsb pdb:6K58|rcsb pdb:6K9S|rcsb pdb:6K24	-	-	comment:mint	figure legend:Figure 3, Table S2, S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/05/29	2019/09/19	-	rogid:Oqu3y1hkk4FKpdRjfHQQkRz2qPQ1348623	-	false	-	mutation with no effect:83-83,88-88	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:83499"	uniprotkb:P14779	intact:EBI-21444823	intact:EBI-7701704|ensemblbacteria:AJI21949|intact:MINT-8313368|uniprotkb:A0A0B6AQ66|uniprotkb:Q9AE23	psi-mi:climbazole(display_short)|psi-mi:"CHEBI:83499"(display_long)|intact:"rac-1-(4-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethylbutan-2-one"(iupac name)|intact:"(RS)-1-(4-chlorophenoxy)-1-imidazol-1-yl-3,3-dimethylbutan-2-one"(synonym)|intact:"1-(p-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethyl -2-butanone"(synonym)|intact:climbazol(synonym)|intact:climbazole(synonym)|intact:Climbazolum(synonym)	psi-mi:cpxb_bacmb(display_long)|uniprotkb:cyp102A1(gene name)|psi-mi:cyp102A1(display_short)|uniprotkb:"Cytochrome P450(BM-3)"(gene name synonym)|uniprotkb:cyp102(gene name synonym)|uniprotkb:Cytochrome P450BM-3(gene name synonym)|uniprotkb:Fatty acid monooxygenase(gene name synonym)|uniprotkb:Flavocytochrome P450 BM3(gene name synonym)|uniprotkb:BG04_163(orf name)	psi-mi:"MI:0042"(electron paramagnetic resonance)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1348623(bacmb)|taxid:1348623(bacmb)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21445586|imex:IM-27046-29	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:5XHJ|rcsb pdb:5E7Y|rcsb pdb:4ZF6|rcsb pdb:4ZF8|rcsb pdb:4ZFA|rcsb pdb:4ZFB|rcsb pdb:5E78|rcsb pdb:5JQ2|rcsb pdb:5JQU|rcsb pdb:5JQV|rcsb pdb:5JTD|interpro:IPR023173|rcsb pdb:5XA3|ensemblbacteria:AJI21949(transcript)|ensemblbacteria:BG04_163(gene)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070330"(aromatase activity)|rcsb pdb:3WSP|rcsb pdb:5OG9|rcsb pdb:5ZLH|rcsb pdb:4RSN|rcsb pdb:6K3Q|rcsb pdb:6L1A|rcsb pdb:6L1B|rcsb pdb:1SMJ|rcsb pdb:4DUE|rcsb pdb:4DUB|rcsb pdb:3NPL|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|rcsb pdb:4HGI|rcsb pdb:4DUF|rcsb pdb:1JPZ|interpro:IPR001128(Cytochrome P450)|rcsb pdb:3DGI|rcsb pdb:2J1M|rcsb pdb:4DUC|rcsb pdb:3HF2|interpro:IPR023206|rcsb pdb:4DQK|rcsb pdb:1ZO9|rcsb pdb:3CBD|rcsb pdb:2IJ2|rcsb pdb:2UWH|rcsb pdb:1ZO4|rcsb pdb:4HGH|rcsb pdb:1JME|rcsb pdb:2X7Y|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|rcsb pdb:3KX4|rcsb pdb:1BVY|rcsb pdb:1YQP|rcsb pdb:2BMH|rcsb pdb:4DU2|rcsb pdb:3EKF|rcsb pdb:2HPD|interpro:IPR017927|rcsb pdb:3EKD|rcsb pdb:1SMI|rcsb pdb:4DUA|rcsb pdb:4DTY|rcsb pdb:3KX3|rcsb pdb:3M4V|rcsb pdb:4DUD|rcsb pdb:4HGF|rcsb pdb:4DTZ|rcsb pdb:1BU7|interpro:IPR001094(Flavodoxin-like)|rcsb pdb:2X80|rcsb pdb:1YQO|interpro:IPR017972|rcsb pdb:1FAH|rcsb pdb:3KX5|rcsb pdb:4DQL|rcsb pdb:1P0X|rcsb pdb:1P0V|rcsb pdb:3PSX|rcsb pdb:2IJ3|rcsb pdb:3EKB|interpro:IPR017938|rcsb pdb:2IJ4|rcsb pdb:4HGG|rcsb pdb:4HGJ|rcsb pdb:1P0W|rcsb pdb:3BEN|rcsb pdb:2J4S|rcsb pdb:1ZOA|rcsb pdb:2NNB|rcsb pdb:4DTW|rcsb pdb:1FAG|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|rcsb pdb:5DYP|rcsb pdb:5DYZ|rcsb pdb:5E9Z|rcsb pdb:4KPA|rcsb pdb:4KPB|rcsb pdb:4H23|rcsb pdb:4H24|rcsb pdb:4KEW|rcsb pdb:4KEY|rcsb pdb:4KF0|rcsb pdb:4KF2|rcsb pdb:4O4P|refseq:WP_034650526.1|interpro:IPR029039|rcsb pdb:4WG2|rcsb pdb:5B2U|rcsb pdb:5B2V|rcsb pdb:5B2W|rcsb pdb:5B2X|rcsb pdb:5B2Y|interpro:IPR036396|rcsb pdb:5UCW|interpro:IPR039261|rcsb pdb:5ZIS|rcsb pdb:6H1O|rcsb pdb:6H1S|rcsb pdb:6IAO|rcsb pdb:6HN8|rcsb pdb:6LY4|rcsb pdb:6JLV|rcsb pdb:6JMH|rcsb pdb:6JMW|rcsb pdb:6JO1|rcsb pdb:6JS8|rcsb pdb:6JVC|rcsb pdb:6JZS|rcsb pdb:6K58|rcsb pdb:6K9S|rcsb pdb:6K24	-	-	comment:mint	figure legend:Table S2, S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/05/29	2019/09/19	-	rogid:Oqu3y1hkk4FKpdRjfHQQkRz2qPQ1348623	-	false	-	mutation with no effect:83-83,88-88	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:3764"	uniprotkb:P14779	intact:EBI-21444840	intact:EBI-7701704|ensemblbacteria:AJI21949|intact:MINT-8313368|uniprotkb:A0A0B6AQ66|uniprotkb:Q9AE23	psi-mi:clotrimazole(display_short)|psi-mi:"CHEBI:3764"(display_long)|intact:"1-((2-Chlorophenyl)diphenylmethyl)-1H-imidazole"(synonym)|intact:"1-(alpha-(2-Chlorophenyl)benzhydryl)imidazole"(synonym)|intact:"1-(o-Chloro-alpha,alpha-diphenylbenzyl)imidazole"(synonym)|intact:"1-(o-Chlorotrityl)imidazole"(synonym)|intact:Clotrimazole(synonym)|intact:"Lotrimin (TN)"(synonym)|intact:"Mycelex (TN)"(synonym)|intact:"1-[(2-chlorophenyl)(diphenyl)methyl]-1H-imidazole"(iupac name)	psi-mi:cpxb_bacmb(display_long)|uniprotkb:cyp102A1(gene name)|psi-mi:cyp102A1(display_short)|uniprotkb:"Cytochrome P450(BM-3)"(gene name synonym)|uniprotkb:cyp102(gene name synonym)|uniprotkb:Cytochrome P450BM-3(gene name synonym)|uniprotkb:Fatty acid monooxygenase(gene name synonym)|uniprotkb:Flavocytochrome P450 BM3(gene name synonym)|uniprotkb:BG04_163(orf name)	psi-mi:"MI:0042"(electron paramagnetic resonance)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1348623(bacmb)|taxid:1348623(bacmb)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21445622|imex:IM-27046-49	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:5XHJ|rcsb pdb:5E7Y|rcsb pdb:4ZF6|rcsb pdb:4ZF8|rcsb pdb:4ZFA|rcsb pdb:4ZFB|rcsb pdb:5E78|rcsb pdb:5JQ2|rcsb pdb:5JQU|rcsb pdb:5JQV|rcsb pdb:5JTD|interpro:IPR023173|rcsb pdb:5XA3|ensemblbacteria:AJI21949(transcript)|ensemblbacteria:BG04_163(gene)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070330"(aromatase activity)|rcsb pdb:3WSP|rcsb pdb:5OG9|rcsb pdb:5ZLH|rcsb pdb:4RSN|rcsb pdb:6K3Q|rcsb pdb:6L1A|rcsb pdb:6L1B|rcsb pdb:1SMJ|rcsb pdb:4DUE|rcsb pdb:4DUB|rcsb pdb:3NPL|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|rcsb pdb:4HGI|rcsb pdb:4DUF|rcsb pdb:1JPZ|interpro:IPR001128(Cytochrome P450)|rcsb pdb:3DGI|rcsb pdb:2J1M|rcsb pdb:4DUC|rcsb pdb:3HF2|interpro:IPR023206|rcsb pdb:4DQK|rcsb pdb:1ZO9|rcsb pdb:3CBD|rcsb pdb:2IJ2|rcsb pdb:2UWH|rcsb pdb:1ZO4|rcsb pdb:4HGH|rcsb pdb:1JME|rcsb pdb:2X7Y|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|rcsb pdb:3KX4|rcsb pdb:1BVY|rcsb pdb:1YQP|rcsb pdb:2BMH|rcsb pdb:4DU2|rcsb pdb:3EKF|rcsb pdb:2HPD|interpro:IPR017927|rcsb pdb:3EKD|rcsb pdb:1SMI|rcsb pdb:4DUA|rcsb pdb:4DTY|rcsb pdb:3KX3|rcsb pdb:3M4V|rcsb pdb:4DUD|rcsb pdb:4HGF|rcsb pdb:4DTZ|rcsb pdb:1BU7|interpro:IPR001094(Flavodoxin-like)|rcsb pdb:2X80|rcsb pdb:1YQO|interpro:IPR017972|rcsb pdb:1FAH|rcsb pdb:3KX5|rcsb pdb:4DQL|rcsb pdb:1P0X|rcsb pdb:1P0V|rcsb pdb:3PSX|rcsb pdb:2IJ3|rcsb pdb:3EKB|interpro:IPR017938|rcsb pdb:2IJ4|rcsb pdb:4HGG|rcsb pdb:4HGJ|rcsb pdb:1P0W|rcsb pdb:3BEN|rcsb pdb:2J4S|rcsb pdb:1ZOA|rcsb pdb:2NNB|rcsb pdb:4DTW|rcsb pdb:1FAG|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|rcsb pdb:5DYP|rcsb pdb:5DYZ|rcsb pdb:5E9Z|rcsb pdb:4KPA|rcsb pdb:4KPB|rcsb pdb:4H23|rcsb pdb:4H24|rcsb pdb:4KEW|rcsb pdb:4KEY|rcsb pdb:4KF0|rcsb pdb:4KF2|rcsb pdb:4O4P|refseq:WP_034650526.1|interpro:IPR029039|rcsb pdb:4WG2|rcsb pdb:5B2U|rcsb pdb:5B2V|rcsb pdb:5B2W|rcsb pdb:5B2X|rcsb pdb:5B2Y|interpro:IPR036396|rcsb pdb:5UCW|interpro:IPR039261|rcsb pdb:5ZIS|rcsb pdb:6H1O|rcsb pdb:6H1S|rcsb pdb:6IAO|rcsb pdb:6HN8|rcsb pdb:6LY4|rcsb pdb:6JLV|rcsb pdb:6JMH|rcsb pdb:6JMW|rcsb pdb:6JO1|rcsb pdb:6JS8|rcsb pdb:6JVC|rcsb pdb:6JZS|rcsb pdb:6K58|rcsb pdb:6K9S|rcsb pdb:6K24	-	-	comment:mint	figure legend:Table S2, S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/05/29	2019/09/19	-	rogid:Oqu3y1hkk4FKpdRjfHQQkRz2qPQ1348623	-	false	-	mutation with no effect:83-83,88-88	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:4755"	uniprotkb:P14779	intact:EBI-21444862	intact:EBI-7701704|ensemblbacteria:AJI21949|intact:MINT-8313368|uniprotkb:A0A0B6AQ66|uniprotkb:Q9AE23	psi-mi:econazole nitrate(display_short)|psi-mi:"CHEBI:4755"(display_long)|intact:"(+-)-econazole nitrate"(synonym)|intact:"(RS)-econazole nitrate"(synonym)|intact:"1-(2,4-Dichloro-beta-((p-chlorobenzyl)oxy)phenethyl)imidazole nitrate"(synonym)|intact:Econazole mononitrate(synonym)|intact:rac-econazole nitrate(synonym)|intact:Spectazole(synonym)|intact:"1-{2-[(4-chlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole nitrate"(iupac name)	psi-mi:cpxb_bacmb(display_long)|uniprotkb:cyp102A1(gene name)|psi-mi:cyp102A1(display_short)|uniprotkb:"Cytochrome P450(BM-3)"(gene name synonym)|uniprotkb:cyp102(gene name synonym)|uniprotkb:Cytochrome P450BM-3(gene name synonym)|uniprotkb:Fatty acid monooxygenase(gene name synonym)|uniprotkb:Flavocytochrome P450 BM3(gene name synonym)|uniprotkb:BG04_163(orf name)	psi-mi:"MI:0042"(electron paramagnetic resonance)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1348623(bacmb)|taxid:1348623(bacmb)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21445632|imex:IM-27046-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:5XHJ|rcsb pdb:5E7Y|rcsb pdb:4ZF6|rcsb pdb:4ZF8|rcsb pdb:4ZFA|rcsb pdb:4ZFB|rcsb pdb:5E78|rcsb pdb:5JQ2|rcsb pdb:5JQU|rcsb pdb:5JQV|rcsb pdb:5JTD|interpro:IPR023173|rcsb pdb:5XA3|ensemblbacteria:AJI21949(transcript)|ensemblbacteria:BG04_163(gene)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070330"(aromatase activity)|rcsb pdb:3WSP|rcsb pdb:5OG9|rcsb pdb:5ZLH|rcsb pdb:4RSN|rcsb pdb:6K3Q|rcsb pdb:6L1A|rcsb pdb:6L1B|rcsb pdb:1SMJ|rcsb pdb:4DUE|rcsb pdb:4DUB|rcsb pdb:3NPL|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|rcsb pdb:4HGI|rcsb pdb:4DUF|rcsb pdb:1JPZ|interpro:IPR001128(Cytochrome P450)|rcsb pdb:3DGI|rcsb pdb:2J1M|rcsb pdb:4DUC|rcsb pdb:3HF2|interpro:IPR023206|rcsb pdb:4DQK|rcsb pdb:1ZO9|rcsb pdb:3CBD|rcsb pdb:2IJ2|rcsb pdb:2UWH|rcsb pdb:1ZO4|rcsb pdb:4HGH|rcsb pdb:1JME|rcsb pdb:2X7Y|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|rcsb pdb:3KX4|rcsb pdb:1BVY|rcsb pdb:1YQP|rcsb pdb:2BMH|rcsb pdb:4DU2|rcsb pdb:3EKF|rcsb pdb:2HPD|interpro:IPR017927|rcsb pdb:3EKD|rcsb pdb:1SMI|rcsb pdb:4DUA|rcsb pdb:4DTY|rcsb pdb:3KX3|rcsb pdb:3M4V|rcsb pdb:4DUD|rcsb pdb:4HGF|rcsb pdb:4DTZ|rcsb pdb:1BU7|interpro:IPR001094(Flavodoxin-like)|rcsb pdb:2X80|rcsb pdb:1YQO|interpro:IPR017972|rcsb pdb:1FAH|rcsb pdb:3KX5|rcsb pdb:4DQL|rcsb pdb:1P0X|rcsb pdb:1P0V|rcsb pdb:3PSX|rcsb pdb:2IJ3|rcsb pdb:3EKB|interpro:IPR017938|rcsb pdb:2IJ4|rcsb pdb:4HGG|rcsb pdb:4HGJ|rcsb pdb:1P0W|rcsb pdb:3BEN|rcsb pdb:2J4S|rcsb pdb:1ZOA|rcsb pdb:2NNB|rcsb pdb:4DTW|rcsb pdb:1FAG|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|rcsb pdb:5DYP|rcsb pdb:5DYZ|rcsb pdb:5E9Z|rcsb pdb:4KPA|rcsb pdb:4KPB|rcsb pdb:4H23|rcsb pdb:4H24|rcsb pdb:4KEW|rcsb pdb:4KEY|rcsb pdb:4KF0|rcsb pdb:4KF2|rcsb pdb:4O4P|refseq:WP_034650526.1|interpro:IPR029039|rcsb pdb:4WG2|rcsb pdb:5B2U|rcsb pdb:5B2V|rcsb pdb:5B2W|rcsb pdb:5B2X|rcsb pdb:5B2Y|interpro:IPR036396|rcsb pdb:5UCW|interpro:IPR039261|rcsb pdb:5ZIS|rcsb pdb:6H1O|rcsb pdb:6H1S|rcsb pdb:6IAO|rcsb pdb:6HN8|rcsb pdb:6LY4|rcsb pdb:6JLV|rcsb pdb:6JMH|rcsb pdb:6JMW|rcsb pdb:6JO1|rcsb pdb:6JS8|rcsb pdb:6JVC|rcsb pdb:6JZS|rcsb pdb:6K58|rcsb pdb:6K9S|rcsb pdb:6K24	-	-	comment:mint	figure legend:Table S2, S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/05/29	2019/09/19	-	rogid:Oqu3y1hkk4FKpdRjfHQQkRz2qPQ1348623	-	false	-	mutation with no effect:83-83,88-88	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:83606"	uniprotkb:P14779	intact:EBI-21444917	intact:EBI-7701704|ensemblbacteria:AJI21949|intact:MINT-8313368|uniprotkb:A0A0B6AQ66|uniprotkb:Q9AE23	psi-mi:fenticonazole nitrate(display_short)|psi-mi:"CHEBI:83606"(display_long)|intact:"(+-)-1-(2,4-Dichloro-beta-((p-(phenylthio)benzyl)oxy)phenethyl)imidazole mononitrate"(synonym)|intact:"alpha-(2,4-Dichlorophenyl)-beta,N-imidazolylethyl-4-phenylthiobenzyl ether nitrate"(synonym)|intact:fenticonazole mononitrate(synonym)|intact:Lomexin(synonym)|intact:"rac-1-[2-(2,4-dichlorophenyl)-2-{[4-(phenylsulfanyl)benzyl]oxy}ethyl]-1H-imidazole nitrate"(iupac name)	psi-mi:cpxb_bacmb(display_long)|uniprotkb:cyp102A1(gene name)|psi-mi:cyp102A1(display_short)|uniprotkb:"Cytochrome P450(BM-3)"(gene name synonym)|uniprotkb:cyp102(gene name synonym)|uniprotkb:Cytochrome P450BM-3(gene name synonym)|uniprotkb:Fatty acid monooxygenase(gene name synonym)|uniprotkb:Flavocytochrome P450 BM3(gene name synonym)|uniprotkb:BG04_163(orf name)	psi-mi:"MI:0042"(electron paramagnetic resonance)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1348623(bacmb)|taxid:1348623(bacmb)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21445641|imex:IM-27046-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:5XHJ|rcsb pdb:5E7Y|rcsb pdb:4ZF6|rcsb pdb:4ZF8|rcsb pdb:4ZFA|rcsb pdb:4ZFB|rcsb pdb:5E78|rcsb pdb:5JQ2|rcsb pdb:5JQU|rcsb pdb:5JQV|rcsb pdb:5JTD|interpro:IPR023173|rcsb pdb:5XA3|ensemblbacteria:AJI21949(transcript)|ensemblbacteria:BG04_163(gene)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070330"(aromatase activity)|rcsb pdb:3WSP|rcsb pdb:5OG9|rcsb pdb:5ZLH|rcsb pdb:4RSN|rcsb pdb:6K3Q|rcsb pdb:6L1A|rcsb pdb:6L1B|rcsb pdb:1SMJ|rcsb pdb:4DUE|rcsb pdb:4DUB|rcsb pdb:3NPL|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|rcsb pdb:4HGI|rcsb pdb:4DUF|rcsb pdb:1JPZ|interpro:IPR001128(Cytochrome P450)|rcsb pdb:3DGI|rcsb pdb:2J1M|rcsb pdb:4DUC|rcsb pdb:3HF2|interpro:IPR023206|rcsb pdb:4DQK|rcsb pdb:1ZO9|rcsb pdb:3CBD|rcsb pdb:2IJ2|rcsb pdb:2UWH|rcsb pdb:1ZO4|rcsb pdb:4HGH|rcsb pdb:1JME|rcsb pdb:2X7Y|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|rcsb pdb:3KX4|rcsb pdb:1BVY|rcsb pdb:1YQP|rcsb pdb:2BMH|rcsb pdb:4DU2|rcsb pdb:3EKF|rcsb pdb:2HPD|interpro:IPR017927|rcsb pdb:3EKD|rcsb pdb:1SMI|rcsb pdb:4DUA|rcsb pdb:4DTY|rcsb pdb:3KX3|rcsb pdb:3M4V|rcsb pdb:4DUD|rcsb pdb:4HGF|rcsb pdb:4DTZ|rcsb pdb:1BU7|interpro:IPR001094(Flavodoxin-like)|rcsb pdb:2X80|rcsb pdb:1YQO|interpro:IPR017972|rcsb pdb:1FAH|rcsb pdb:3KX5|rcsb pdb:4DQL|rcsb pdb:1P0X|rcsb pdb:1P0V|rcsb pdb:3PSX|rcsb pdb:2IJ3|rcsb pdb:3EKB|interpro:IPR017938|rcsb pdb:2IJ4|rcsb pdb:4HGG|rcsb pdb:4HGJ|rcsb pdb:1P0W|rcsb pdb:3BEN|rcsb pdb:2J4S|rcsb pdb:1ZOA|rcsb pdb:2NNB|rcsb pdb:4DTW|rcsb pdb:1FAG|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|rcsb pdb:5DYP|rcsb pdb:5DYZ|rcsb pdb:5E9Z|rcsb pdb:4KPA|rcsb pdb:4KPB|rcsb pdb:4H23|rcsb pdb:4H24|rcsb pdb:4KEW|rcsb pdb:4KEY|rcsb pdb:4KF0|rcsb pdb:4KF2|rcsb pdb:4O4P|refseq:WP_034650526.1|interpro:IPR029039|rcsb pdb:4WG2|rcsb pdb:5B2U|rcsb pdb:5B2V|rcsb pdb:5B2W|rcsb pdb:5B2X|rcsb pdb:5B2Y|interpro:IPR036396|rcsb pdb:5UCW|interpro:IPR039261|rcsb pdb:5ZIS|rcsb pdb:6H1O|rcsb pdb:6H1S|rcsb pdb:6IAO|rcsb pdb:6HN8|rcsb pdb:6LY4|rcsb pdb:6JLV|rcsb pdb:6JMH|rcsb pdb:6JMW|rcsb pdb:6JO1|rcsb pdb:6JS8|rcsb pdb:6JVC|rcsb pdb:6JZS|rcsb pdb:6K58|rcsb pdb:6K9S|rcsb pdb:6K24	-	-	comment:mint	figure legend:Table S2, S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/05/29	2019/09/19	-	rogid:Oqu3y1hkk4FKpdRjfHQQkRz2qPQ1348623	-	false	-	mutation with no effect:83-83,88-88	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:31728"	uniprotkb:P14779	intact:EBI-21444928	intact:EBI-7701704|ensemblbacteria:AJI21949|intact:MINT-8313368|uniprotkb:A0A0B6AQ66|uniprotkb:Q9AE23	psi-mi:isoconazole nitrate(display_short)|psi-mi:"CHEBI:31728"(display_long)|intact:"(+-)-isoconazole nitrate"(synonym)|intact:"(RS)-isoconazole nitrate"(synonym)|intact:"1-(2,4-Dichloro-beta-(2,6-dichlorobenzyloxy)phenethyl)imidazole nitrate"(synonym)|intact:"1-(2-((2,6-Dichlorobenzyl)oxy)-2-(2,4-dichlorophenyl)ethyl)imidazole nitrate"(synonym)|intact:isoconazole mononitrate(synonym)|intact:rac-isoconazole nitrate(synonym)|intact:racemic isoconazole nitrate(synonym)|intact:"rac-1-{2-[(2,6-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole nitrate"(iupac name)	psi-mi:cpxb_bacmb(display_long)|uniprotkb:cyp102A1(gene name)|psi-mi:cyp102A1(display_short)|uniprotkb:"Cytochrome P450(BM-3)"(gene name synonym)|uniprotkb:cyp102(gene name synonym)|uniprotkb:Cytochrome P450BM-3(gene name synonym)|uniprotkb:Fatty acid monooxygenase(gene name synonym)|uniprotkb:Flavocytochrome P450 BM3(gene name synonym)|uniprotkb:BG04_163(orf name)	psi-mi:"MI:0042"(electron paramagnetic resonance)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1348623(bacmb)|taxid:1348623(bacmb)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21445651|imex:IM-27046-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:5XHJ|rcsb pdb:5E7Y|rcsb pdb:4ZF6|rcsb pdb:4ZF8|rcsb pdb:4ZFA|rcsb pdb:4ZFB|rcsb pdb:5E78|rcsb pdb:5JQ2|rcsb pdb:5JQU|rcsb pdb:5JQV|rcsb pdb:5JTD|interpro:IPR023173|rcsb pdb:5XA3|ensemblbacteria:AJI21949(transcript)|ensemblbacteria:BG04_163(gene)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070330"(aromatase activity)|rcsb pdb:3WSP|rcsb pdb:5OG9|rcsb pdb:5ZLH|rcsb pdb:4RSN|rcsb pdb:6K3Q|rcsb pdb:6L1A|rcsb pdb:6L1B|rcsb pdb:1SMJ|rcsb pdb:4DUE|rcsb pdb:4DUB|rcsb pdb:3NPL|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|rcsb pdb:4HGI|rcsb pdb:4DUF|rcsb pdb:1JPZ|interpro:IPR001128(Cytochrome P450)|rcsb pdb:3DGI|rcsb pdb:2J1M|rcsb pdb:4DUC|rcsb pdb:3HF2|interpro:IPR023206|rcsb pdb:4DQK|rcsb pdb:1ZO9|rcsb pdb:3CBD|rcsb pdb:2IJ2|rcsb pdb:2UWH|rcsb pdb:1ZO4|rcsb pdb:4HGH|rcsb pdb:1JME|rcsb pdb:2X7Y|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|rcsb pdb:3KX4|rcsb pdb:1BVY|rcsb pdb:1YQP|rcsb pdb:2BMH|rcsb pdb:4DU2|rcsb pdb:3EKF|rcsb pdb:2HPD|interpro:IPR017927|rcsb pdb:3EKD|rcsb pdb:1SMI|rcsb pdb:4DUA|rcsb pdb:4DTY|rcsb pdb:3KX3|rcsb pdb:3M4V|rcsb pdb:4DUD|rcsb pdb:4HGF|rcsb pdb:4DTZ|rcsb pdb:1BU7|interpro:IPR001094(Flavodoxin-like)|rcsb pdb:2X80|rcsb pdb:1YQO|interpro:IPR017972|rcsb pdb:1FAH|rcsb pdb:3KX5|rcsb pdb:4DQL|rcsb pdb:1P0X|rcsb pdb:1P0V|rcsb pdb:3PSX|rcsb pdb:2IJ3|rcsb pdb:3EKB|interpro:IPR017938|rcsb pdb:2IJ4|rcsb pdb:4HGG|rcsb pdb:4HGJ|rcsb pdb:1P0W|rcsb pdb:3BEN|rcsb pdb:2J4S|rcsb pdb:1ZOA|rcsb pdb:2NNB|rcsb pdb:4DTW|rcsb pdb:1FAG|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|rcsb pdb:5DYP|rcsb pdb:5DYZ|rcsb pdb:5E9Z|rcsb pdb:4KPA|rcsb pdb:4KPB|rcsb pdb:4H23|rcsb pdb:4H24|rcsb pdb:4KEW|rcsb pdb:4KEY|rcsb pdb:4KF0|rcsb pdb:4KF2|rcsb pdb:4O4P|refseq:WP_034650526.1|interpro:IPR029039|rcsb pdb:4WG2|rcsb pdb:5B2U|rcsb pdb:5B2V|rcsb pdb:5B2W|rcsb pdb:5B2X|rcsb pdb:5B2Y|interpro:IPR036396|rcsb pdb:5UCW|interpro:IPR039261|rcsb pdb:5ZIS|rcsb pdb:6H1O|rcsb pdb:6H1S|rcsb pdb:6IAO|rcsb pdb:6HN8|rcsb pdb:6LY4|rcsb pdb:6JLV|rcsb pdb:6JMH|rcsb pdb:6JMW|rcsb pdb:6JO1|rcsb pdb:6JS8|rcsb pdb:6JVC|rcsb pdb:6JZS|rcsb pdb:6K58|rcsb pdb:6K9S|rcsb pdb:6K24	-	-	comment:mint	figure legend:Table S2, S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/05/29	2019/09/19	-	rogid:Oqu3y1hkk4FKpdRjfHQQkRz2qPQ1348623	-	false	-	mutation with no effect:83-83,88-88	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:47519"	uniprotkb:P14779	intact:EBI-21444955|chebi:"CHEBI:6126"	intact:EBI-7701704|ensemblbacteria:AJI21949|intact:MINT-8313368|uniprotkb:A0A0B6AQ66|uniprotkb:Q9AE23	psi-mi:ketoconazole(display_short)|psi-mi:"CHEBI:47519"(display_long)|intact:Fungarest(synonym)|intact:Fungoral(synonym)|intact:ketoconazol(synonym)|intact:ketoconazole(synonym)|intact:ketoconazolum(synonym)|intact:Ketoderm(synonym)|intact:Ketoisdin(synonym)|intact:Nizoral(synonym)|intact:Panfungol(synonym)|intact:Xolegel(synonym)|intact:"rac-1-acetyl-4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine"(iupac name)|intact:"(+-)-cis-1-acetyl-4-(p-((2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazine"(synonym)|intact:"cis-1-acetyl-4-(4-((2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazine"(synonym)	psi-mi:cpxb_bacmb(display_long)|uniprotkb:cyp102A1(gene name)|psi-mi:cyp102A1(display_short)|uniprotkb:"Cytochrome P450(BM-3)"(gene name synonym)|uniprotkb:cyp102(gene name synonym)|uniprotkb:Cytochrome P450BM-3(gene name synonym)|uniprotkb:Fatty acid monooxygenase(gene name synonym)|uniprotkb:Flavocytochrome P450 BM3(gene name synonym)|uniprotkb:BG04_163(orf name)	psi-mi:"MI:0042"(electron paramagnetic resonance)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1348623(bacmb)|taxid:1348623(bacmb)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21445660|imex:IM-27046-31	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:5XHJ|rcsb pdb:5E7Y|rcsb pdb:4ZF6|rcsb pdb:4ZF8|rcsb pdb:4ZFA|rcsb pdb:4ZFB|rcsb pdb:5E78|rcsb pdb:5JQ2|rcsb pdb:5JQU|rcsb pdb:5JQV|rcsb pdb:5JTD|interpro:IPR023173|rcsb pdb:5XA3|ensemblbacteria:AJI21949(transcript)|ensemblbacteria:BG04_163(gene)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070330"(aromatase activity)|rcsb pdb:3WSP|rcsb pdb:5OG9|rcsb pdb:5ZLH|rcsb pdb:4RSN|rcsb pdb:6K3Q|rcsb pdb:6L1A|rcsb pdb:6L1B|rcsb pdb:1SMJ|rcsb pdb:4DUE|rcsb pdb:4DUB|rcsb pdb:3NPL|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|rcsb pdb:4HGI|rcsb pdb:4DUF|rcsb pdb:1JPZ|interpro:IPR001128(Cytochrome P450)|rcsb pdb:3DGI|rcsb pdb:2J1M|rcsb pdb:4DUC|rcsb pdb:3HF2|interpro:IPR023206|rcsb pdb:4DQK|rcsb pdb:1ZO9|rcsb pdb:3CBD|rcsb pdb:2IJ2|rcsb pdb:2UWH|rcsb pdb:1ZO4|rcsb pdb:4HGH|rcsb pdb:1JME|rcsb pdb:2X7Y|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|rcsb pdb:3KX4|rcsb pdb:1BVY|rcsb pdb:1YQP|rcsb pdb:2BMH|rcsb pdb:4DU2|rcsb pdb:3EKF|rcsb pdb:2HPD|interpro:IPR017927|rcsb pdb:3EKD|rcsb pdb:1SMI|rcsb pdb:4DUA|rcsb pdb:4DTY|rcsb pdb:3KX3|rcsb pdb:3M4V|rcsb pdb:4DUD|rcsb pdb:4HGF|rcsb pdb:4DTZ|rcsb pdb:1BU7|interpro:IPR001094(Flavodoxin-like)|rcsb pdb:2X80|rcsb pdb:1YQO|interpro:IPR017972|rcsb pdb:1FAH|rcsb pdb:3KX5|rcsb pdb:4DQL|rcsb pdb:1P0X|rcsb pdb:1P0V|rcsb pdb:3PSX|rcsb pdb:2IJ3|rcsb pdb:3EKB|interpro:IPR017938|rcsb pdb:2IJ4|rcsb pdb:4HGG|rcsb pdb:4HGJ|rcsb pdb:1P0W|rcsb pdb:3BEN|rcsb pdb:2J4S|rcsb pdb:1ZOA|rcsb pdb:2NNB|rcsb pdb:4DTW|rcsb pdb:1FAG|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|rcsb pdb:5DYP|rcsb pdb:5DYZ|rcsb pdb:5E9Z|rcsb pdb:4KPA|rcsb pdb:4KPB|rcsb pdb:4H23|rcsb pdb:4H24|rcsb pdb:4KEW|rcsb pdb:4KEY|rcsb pdb:4KF0|rcsb pdb:4KF2|rcsb pdb:4O4P|refseq:WP_034650526.1|interpro:IPR029039|rcsb pdb:4WG2|rcsb pdb:5B2U|rcsb pdb:5B2V|rcsb pdb:5B2W|rcsb pdb:5B2X|rcsb pdb:5B2Y|interpro:IPR036396|rcsb pdb:5UCW|interpro:IPR039261|rcsb pdb:5ZIS|rcsb pdb:6H1O|rcsb pdb:6H1S|rcsb pdb:6IAO|rcsb pdb:6HN8|rcsb pdb:6LY4|rcsb pdb:6JLV|rcsb pdb:6JMH|rcsb pdb:6JMW|rcsb pdb:6JO1|rcsb pdb:6JS8|rcsb pdb:6JVC|rcsb pdb:6JZS|rcsb pdb:6K58|rcsb pdb:6K9S|rcsb pdb:6K24	-	-	comment:mint	figure legend:Table S2, S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/05/29	2019/09/19	-	rogid:Oqu3y1hkk4FKpdRjfHQQkRz2qPQ1348623	-	false	-	mutation with no effect:83-83,88-88	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:6076"	uniprotkb:P14779	intact:EBI-21445742	intact:EBI-7701704|ensemblbacteria:AJI21949|intact:MINT-8313368|uniprotkb:A0A0B6AQ66|uniprotkb:Q9AE23	psi-mi:itraconazole(display_short)|psi-mi:"CHEBI:6076"(display_long)|intact:Itraconazole(synonym)|intact:"Itrizole (TN)"(synonym)|intact:Oriconazole(synonym)|intact:"Sporanox (TN)"(synonym)|intact:"2-(butan-2-yl)-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-2,4-dihydro-3H-1,2,4-triazol-3-one"(iupac name)	psi-mi:cpxb_bacmb(display_long)|uniprotkb:cyp102A1(gene name)|psi-mi:cyp102A1(display_short)|uniprotkb:"Cytochrome P450(BM-3)"(gene name synonym)|uniprotkb:cyp102(gene name synonym)|uniprotkb:Cytochrome P450BM-3(gene name synonym)|uniprotkb:Fatty acid monooxygenase(gene name synonym)|uniprotkb:Flavocytochrome P450 BM3(gene name synonym)|uniprotkb:BG04_163(orf name)	psi-mi:"MI:0042"(electron paramagnetic resonance)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1348623(bacmb)|taxid:1348623(bacmb)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21445925|imex:IM-27046-33	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:5XHJ|rcsb pdb:5E7Y|rcsb pdb:4ZF6|rcsb pdb:4ZF8|rcsb pdb:4ZFA|rcsb pdb:4ZFB|rcsb pdb:5E78|rcsb pdb:5JQ2|rcsb pdb:5JQU|rcsb pdb:5JQV|rcsb pdb:5JTD|interpro:IPR023173|rcsb pdb:5XA3|ensemblbacteria:AJI21949(transcript)|ensemblbacteria:BG04_163(gene)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070330"(aromatase activity)|rcsb pdb:3WSP|rcsb pdb:5OG9|rcsb pdb:5ZLH|rcsb pdb:4RSN|rcsb pdb:6K3Q|rcsb pdb:6L1A|rcsb pdb:6L1B|rcsb pdb:1SMJ|rcsb pdb:4DUE|rcsb pdb:4DUB|rcsb pdb:3NPL|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|rcsb pdb:4HGI|rcsb pdb:4DUF|rcsb pdb:1JPZ|interpro:IPR001128(Cytochrome P450)|rcsb pdb:3DGI|rcsb pdb:2J1M|rcsb pdb:4DUC|rcsb pdb:3HF2|interpro:IPR023206|rcsb pdb:4DQK|rcsb pdb:1ZO9|rcsb pdb:3CBD|rcsb pdb:2IJ2|rcsb pdb:2UWH|rcsb pdb:1ZO4|rcsb pdb:4HGH|rcsb pdb:1JME|rcsb pdb:2X7Y|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|rcsb pdb:3KX4|rcsb pdb:1BVY|rcsb pdb:1YQP|rcsb pdb:2BMH|rcsb pdb:4DU2|rcsb pdb:3EKF|rcsb pdb:2HPD|interpro:IPR017927|rcsb pdb:3EKD|rcsb pdb:1SMI|rcsb pdb:4DUA|rcsb pdb:4DTY|rcsb pdb:3KX3|rcsb pdb:3M4V|rcsb pdb:4DUD|rcsb pdb:4HGF|rcsb pdb:4DTZ|rcsb pdb:1BU7|interpro:IPR001094(Flavodoxin-like)|rcsb pdb:2X80|rcsb pdb:1YQO|interpro:IPR017972|rcsb pdb:1FAH|rcsb pdb:3KX5|rcsb pdb:4DQL|rcsb pdb:1P0X|rcsb pdb:1P0V|rcsb pdb:3PSX|rcsb pdb:2IJ3|rcsb pdb:3EKB|interpro:IPR017938|rcsb pdb:2IJ4|rcsb pdb:4HGG|rcsb pdb:4HGJ|rcsb pdb:1P0W|rcsb pdb:3BEN|rcsb pdb:2J4S|rcsb pdb:1ZOA|rcsb pdb:2NNB|rcsb pdb:4DTW|rcsb pdb:1FAG|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|rcsb pdb:5DYP|rcsb pdb:5DYZ|rcsb pdb:5E9Z|rcsb pdb:4KPA|rcsb pdb:4KPB|rcsb pdb:4H23|rcsb pdb:4H24|rcsb pdb:4KEW|rcsb pdb:4KEY|rcsb pdb:4KF0|rcsb pdb:4KF2|rcsb pdb:4O4P|refseq:WP_034650526.1|interpro:IPR029039|rcsb pdb:4WG2|rcsb pdb:5B2U|rcsb pdb:5B2V|rcsb pdb:5B2W|rcsb pdb:5B2X|rcsb pdb:5B2Y|interpro:IPR036396|rcsb pdb:5UCW|interpro:IPR039261|rcsb pdb:5ZIS|rcsb pdb:6H1O|rcsb pdb:6H1S|rcsb pdb:6IAO|rcsb pdb:6HN8|rcsb pdb:6LY4|rcsb pdb:6JLV|rcsb pdb:6JMH|rcsb pdb:6JMW|rcsb pdb:6JO1|rcsb pdb:6JS8|rcsb pdb:6JVC|rcsb pdb:6JZS|rcsb pdb:6K58|rcsb pdb:6K9S|rcsb pdb:6K24	-	-	comment:mint	figure legend:Table S2, S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/05/29	2019/09/19	-	rogid:Oqu3y1hkk4FKpdRjfHQQkRz2qPQ1348623	-	false	-	mutation with no effect:83-83,88-88	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:6923"	uniprotkb:P14779	intact:EBI-21444994|chebi:"CHEBI:108917"	intact:EBI-7701704|ensemblbacteria:AJI21949|intact:MINT-8313368|uniprotkb:A0A0B6AQ66|uniprotkb:Q9AE23	psi-mi:miconazole(display_short)|psi-mi:"CHEBI:6923"(display_long)|intact:"(+-)-miconazole"(synonym)|intact:"(RS)-miconazole"(synonym)|intact:"1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole"(synonym)|intact:"1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole"(synonym)|intact:Daktarin IV(synonym)|intact:Miconazole(synonym)|intact:"Monistat IV (TN)"(synonym)|intact:rac-miconazole(synonym)|intact:"rac-1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole"(iupac name)	psi-mi:cpxb_bacmb(display_long)|uniprotkb:cyp102A1(gene name)|psi-mi:cyp102A1(display_short)|uniprotkb:"Cytochrome P450(BM-3)"(gene name synonym)|uniprotkb:cyp102(gene name synonym)|uniprotkb:Cytochrome P450BM-3(gene name synonym)|uniprotkb:Fatty acid monooxygenase(gene name synonym)|uniprotkb:Flavocytochrome P450 BM3(gene name synonym)|uniprotkb:BG04_163(orf name)	psi-mi:"MI:0042"(electron paramagnetic resonance)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1348623(bacmb)|taxid:1348623(bacmb)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21445933|imex:IM-27046-35	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:5XHJ|rcsb pdb:5E7Y|rcsb pdb:4ZF6|rcsb pdb:4ZF8|rcsb pdb:4ZFA|rcsb pdb:4ZFB|rcsb pdb:5E78|rcsb pdb:5JQ2|rcsb pdb:5JQU|rcsb pdb:5JQV|rcsb pdb:5JTD|interpro:IPR023173|rcsb pdb:5XA3|ensemblbacteria:AJI21949(transcript)|ensemblbacteria:BG04_163(gene)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070330"(aromatase activity)|rcsb pdb:3WSP|rcsb pdb:5OG9|rcsb pdb:5ZLH|rcsb pdb:4RSN|rcsb pdb:6K3Q|rcsb pdb:6L1A|rcsb pdb:6L1B|rcsb pdb:1SMJ|rcsb pdb:4DUE|rcsb pdb:4DUB|rcsb pdb:3NPL|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|rcsb pdb:4HGI|rcsb pdb:4DUF|rcsb pdb:1JPZ|interpro:IPR001128(Cytochrome P450)|rcsb pdb:3DGI|rcsb pdb:2J1M|rcsb pdb:4DUC|rcsb pdb:3HF2|interpro:IPR023206|rcsb pdb:4DQK|rcsb pdb:1ZO9|rcsb pdb:3CBD|rcsb pdb:2IJ2|rcsb pdb:2UWH|rcsb pdb:1ZO4|rcsb pdb:4HGH|rcsb pdb:1JME|rcsb pdb:2X7Y|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|rcsb pdb:3KX4|rcsb pdb:1BVY|rcsb pdb:1YQP|rcsb pdb:2BMH|rcsb pdb:4DU2|rcsb pdb:3EKF|rcsb pdb:2HPD|interpro:IPR017927|rcsb pdb:3EKD|rcsb pdb:1SMI|rcsb pdb:4DUA|rcsb pdb:4DTY|rcsb pdb:3KX3|rcsb pdb:3M4V|rcsb pdb:4DUD|rcsb pdb:4HGF|rcsb pdb:4DTZ|rcsb pdb:1BU7|interpro:IPR001094(Flavodoxin-like)|rcsb pdb:2X80|rcsb pdb:1YQO|interpro:IPR017972|rcsb pdb:1FAH|rcsb pdb:3KX5|rcsb pdb:4DQL|rcsb pdb:1P0X|rcsb pdb:1P0V|rcsb pdb:3PSX|rcsb pdb:2IJ3|rcsb pdb:3EKB|interpro:IPR017938|rcsb pdb:2IJ4|rcsb pdb:4HGG|rcsb pdb:4HGJ|rcsb pdb:1P0W|rcsb pdb:3BEN|rcsb pdb:2J4S|rcsb pdb:1ZOA|rcsb pdb:2NNB|rcsb pdb:4DTW|rcsb pdb:1FAG|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|rcsb pdb:5DYP|rcsb pdb:5DYZ|rcsb pdb:5E9Z|rcsb pdb:4KPA|rcsb pdb:4KPB|rcsb pdb:4H23|rcsb pdb:4H24|rcsb pdb:4KEW|rcsb pdb:4KEY|rcsb pdb:4KF0|rcsb pdb:4KF2|rcsb pdb:4O4P|refseq:WP_034650526.1|interpro:IPR029039|rcsb pdb:4WG2|rcsb pdb:5B2U|rcsb pdb:5B2V|rcsb pdb:5B2W|rcsb pdb:5B2X|rcsb pdb:5B2Y|interpro:IPR036396|rcsb pdb:5UCW|interpro:IPR039261|rcsb pdb:5ZIS|rcsb pdb:6H1O|rcsb pdb:6H1S|rcsb pdb:6IAO|rcsb pdb:6HN8|rcsb pdb:6LY4|rcsb pdb:6JLV|rcsb pdb:6JMH|rcsb pdb:6JMW|rcsb pdb:6JO1|rcsb pdb:6JS8|rcsb pdb:6JVC|rcsb pdb:6JZS|rcsb pdb:6K58|rcsb pdb:6K9S|rcsb pdb:6K24	-	-	comment:mint	figure legend:Table S2, S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/05/29	2019/09/19	-	rogid:Oqu3y1hkk4FKpdRjfHQQkRz2qPQ1348623	-	false	-	mutation with no effect:83-83,88-88	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:64355"	uniprotkb:P14779	intact:EBI-21445797	intact:EBI-7701704|ensemblbacteria:AJI21949|intact:MINT-8313368|uniprotkb:A0A0B6AQ66|uniprotkb:Q9AE23	psi-mi:posaconazole(display_short)|psi-mi:"CHEBI:64355"(display_long)|intact:Noxafil(synonym)|intact:posaconazole(synonym)|intact:Sch 56592(synonym)|intact:SCH56592(synonym)|intact:Schering 56592(synonym)|intact:"2,5-anhydro-1,3,4-trideoxy-2-(2,4-difluorophenyl)-4-({4-[4-(4-{1-[(2S,3S)-2-hydroxypentan-3-yl]-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl}phenyl)piperazin-1-yl]phenoxy}methyl)-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol"(iupac name)	psi-mi:cpxb_bacmb(display_long)|uniprotkb:cyp102A1(gene name)|psi-mi:cyp102A1(display_short)|uniprotkb:"Cytochrome P450(BM-3)"(gene name synonym)|uniprotkb:cyp102(gene name synonym)|uniprotkb:Cytochrome P450BM-3(gene name synonym)|uniprotkb:Fatty acid monooxygenase(gene name synonym)|uniprotkb:Flavocytochrome P450 BM3(gene name synonym)|uniprotkb:BG04_163(orf name)	psi-mi:"MI:0042"(electron paramagnetic resonance)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1348623(bacmb)|taxid:1348623(bacmb)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21445942|imex:IM-27046-75	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:5XHJ|rcsb pdb:5E7Y|rcsb pdb:4ZF6|rcsb pdb:4ZF8|rcsb pdb:4ZFA|rcsb pdb:4ZFB|rcsb pdb:5E78|rcsb pdb:5JQ2|rcsb pdb:5JQU|rcsb pdb:5JQV|rcsb pdb:5JTD|interpro:IPR023173|rcsb pdb:5XA3|ensemblbacteria:AJI21949(transcript)|ensemblbacteria:BG04_163(gene)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070330"(aromatase activity)|rcsb pdb:3WSP|rcsb pdb:5OG9|rcsb pdb:5ZLH|rcsb pdb:4RSN|rcsb pdb:6K3Q|rcsb pdb:6L1A|rcsb pdb:6L1B|rcsb pdb:1SMJ|rcsb pdb:4DUE|rcsb pdb:4DUB|rcsb pdb:3NPL|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|rcsb pdb:4HGI|rcsb pdb:4DUF|rcsb pdb:1JPZ|interpro:IPR001128(Cytochrome P450)|rcsb pdb:3DGI|rcsb pdb:2J1M|rcsb pdb:4DUC|rcsb pdb:3HF2|interpro:IPR023206|rcsb pdb:4DQK|rcsb pdb:1ZO9|rcsb pdb:3CBD|rcsb pdb:2IJ2|rcsb pdb:2UWH|rcsb pdb:1ZO4|rcsb pdb:4HGH|rcsb pdb:1JME|rcsb pdb:2X7Y|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|rcsb pdb:3KX4|rcsb pdb:1BVY|rcsb pdb:1YQP|rcsb pdb:2BMH|rcsb pdb:4DU2|rcsb pdb:3EKF|rcsb pdb:2HPD|interpro:IPR017927|rcsb pdb:3EKD|rcsb pdb:1SMI|rcsb pdb:4DUA|rcsb pdb:4DTY|rcsb pdb:3KX3|rcsb pdb:3M4V|rcsb pdb:4DUD|rcsb pdb:4HGF|rcsb pdb:4DTZ|rcsb pdb:1BU7|interpro:IPR001094(Flavodoxin-like)|rcsb pdb:2X80|rcsb pdb:1YQO|interpro:IPR017972|rcsb pdb:1FAH|rcsb pdb:3KX5|rcsb pdb:4DQL|rcsb pdb:1P0X|rcsb pdb:1P0V|rcsb pdb:3PSX|rcsb pdb:2IJ3|rcsb pdb:3EKB|interpro:IPR017938|rcsb pdb:2IJ4|rcsb pdb:4HGG|rcsb pdb:4HGJ|rcsb pdb:1P0W|rcsb pdb:3BEN|rcsb pdb:2J4S|rcsb pdb:1ZOA|rcsb pdb:2NNB|rcsb pdb:4DTW|rcsb pdb:1FAG|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|rcsb pdb:5DYP|rcsb pdb:5DYZ|rcsb pdb:5E9Z|rcsb pdb:4KPA|rcsb pdb:4KPB|rcsb pdb:4H23|rcsb pdb:4H24|rcsb pdb:4KEW|rcsb pdb:4KEY|rcsb pdb:4KF0|rcsb pdb:4KF2|rcsb pdb:4O4P|refseq:WP_034650526.1|interpro:IPR029039|rcsb pdb:4WG2|rcsb pdb:5B2U|rcsb pdb:5B2V|rcsb pdb:5B2W|rcsb pdb:5B2X|rcsb pdb:5B2Y|interpro:IPR036396|rcsb pdb:5UCW|interpro:IPR039261|rcsb pdb:5ZIS|rcsb pdb:6H1O|rcsb pdb:6H1S|rcsb pdb:6IAO|rcsb pdb:6HN8|rcsb pdb:6LY4|rcsb pdb:6JLV|rcsb pdb:6JMH|rcsb pdb:6JMW|rcsb pdb:6JO1|rcsb pdb:6JS8|rcsb pdb:6JVC|rcsb pdb:6JZS|rcsb pdb:6K58|rcsb pdb:6K9S|rcsb pdb:6K24	-	-	comment:mint	figure legend:Table S2, S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/05/29	2019/09/19	-	rogid:Oqu3y1hkk4FKpdRjfHQQkRz2qPQ1348623	-	false	-	mutation with no effect:83-83,88-88	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:143825"	uniprotkb:P14779	intact:EBI-21445816	intact:EBI-7701704|ensemblbacteria:AJI21949|intact:MINT-8313368|uniprotkb:A0A0B6AQ66|uniprotkb:Q9AE23	psi-mi:ravuconazole(display_short)|psi-mi:"CHEBI:143825"(display_long)	psi-mi:cpxb_bacmb(display_long)|uniprotkb:cyp102A1(gene name)|psi-mi:cyp102A1(display_short)|uniprotkb:"Cytochrome P450(BM-3)"(gene name synonym)|uniprotkb:cyp102(gene name synonym)|uniprotkb:Cytochrome P450BM-3(gene name synonym)|uniprotkb:Fatty acid monooxygenase(gene name synonym)|uniprotkb:Flavocytochrome P450 BM3(gene name synonym)|uniprotkb:BG04_163(orf name)	psi-mi:"MI:0042"(electron paramagnetic resonance)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1348623(bacmb)|taxid:1348623(bacmb)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21445950|imex:IM-27046-53	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:5XHJ|rcsb pdb:5E7Y|rcsb pdb:4ZF6|rcsb pdb:4ZF8|rcsb pdb:4ZFA|rcsb pdb:4ZFB|rcsb pdb:5E78|rcsb pdb:5JQ2|rcsb pdb:5JQU|rcsb pdb:5JQV|rcsb pdb:5JTD|interpro:IPR023173|rcsb pdb:5XA3|ensemblbacteria:AJI21949(transcript)|ensemblbacteria:BG04_163(gene)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070330"(aromatase activity)|rcsb pdb:3WSP|rcsb pdb:5OG9|rcsb pdb:5ZLH|rcsb pdb:4RSN|rcsb pdb:6K3Q|rcsb pdb:6L1A|rcsb pdb:6L1B|rcsb pdb:1SMJ|rcsb pdb:4DUE|rcsb pdb:4DUB|rcsb pdb:3NPL|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|rcsb pdb:4HGI|rcsb pdb:4DUF|rcsb pdb:1JPZ|interpro:IPR001128(Cytochrome P450)|rcsb pdb:3DGI|rcsb pdb:2J1M|rcsb pdb:4DUC|rcsb pdb:3HF2|interpro:IPR023206|rcsb pdb:4DQK|rcsb pdb:1ZO9|rcsb pdb:3CBD|rcsb pdb:2IJ2|rcsb pdb:2UWH|rcsb pdb:1ZO4|rcsb pdb:4HGH|rcsb pdb:1JME|rcsb pdb:2X7Y|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|rcsb pdb:3KX4|rcsb pdb:1BVY|rcsb pdb:1YQP|rcsb pdb:2BMH|rcsb pdb:4DU2|rcsb pdb:3EKF|rcsb pdb:2HPD|interpro:IPR017927|rcsb pdb:3EKD|rcsb pdb:1SMI|rcsb pdb:4DUA|rcsb pdb:4DTY|rcsb pdb:3KX3|rcsb pdb:3M4V|rcsb pdb:4DUD|rcsb pdb:4HGF|rcsb pdb:4DTZ|rcsb pdb:1BU7|interpro:IPR001094(Flavodoxin-like)|rcsb pdb:2X80|rcsb pdb:1YQO|interpro:IPR017972|rcsb pdb:1FAH|rcsb pdb:3KX5|rcsb pdb:4DQL|rcsb pdb:1P0X|rcsb pdb:1P0V|rcsb pdb:3PSX|rcsb pdb:2IJ3|rcsb pdb:3EKB|interpro:IPR017938|rcsb pdb:2IJ4|rcsb pdb:4HGG|rcsb pdb:4HGJ|rcsb pdb:1P0W|rcsb pdb:3BEN|rcsb pdb:2J4S|rcsb pdb:1ZOA|rcsb pdb:2NNB|rcsb pdb:4DTW|rcsb pdb:1FAG|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|rcsb pdb:5DYP|rcsb pdb:5DYZ|rcsb pdb:5E9Z|rcsb pdb:4KPA|rcsb pdb:4KPB|rcsb pdb:4H23|rcsb pdb:4H24|rcsb pdb:4KEW|rcsb pdb:4KEY|rcsb pdb:4KF0|rcsb pdb:4KF2|rcsb pdb:4O4P|refseq:WP_034650526.1|interpro:IPR029039|rcsb pdb:4WG2|rcsb pdb:5B2U|rcsb pdb:5B2V|rcsb pdb:5B2W|rcsb pdb:5B2X|rcsb pdb:5B2Y|interpro:IPR036396|rcsb pdb:5UCW|interpro:IPR039261|rcsb pdb:5ZIS|rcsb pdb:6H1O|rcsb pdb:6H1S|rcsb pdb:6IAO|rcsb pdb:6HN8|rcsb pdb:6LY4|rcsb pdb:6JLV|rcsb pdb:6JMH|rcsb pdb:6JMW|rcsb pdb:6JO1|rcsb pdb:6JS8|rcsb pdb:6JVC|rcsb pdb:6JZS|rcsb pdb:6K58|rcsb pdb:6K9S|rcsb pdb:6K24	-	-	comment:mint	figure legend:Table S2, S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/05/29	2019/09/19	-	rogid:Oqu3y1hkk4FKpdRjfHQQkRz2qPQ1348623	-	false	-	mutation with no effect:83-83,88-88	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:9326"	uniprotkb:P14779	intact:EBI-21445036	intact:EBI-7701704|ensemblbacteria:AJI21949|intact:MINT-8313368|uniprotkb:A0A0B6AQ66|uniprotkb:Q9AE23	psi-mi:sulconazole nitrate(display_short)|psi-mi:"CHEBI:9326"(display_long)|intact:Sulconazole nitrate(synonym)	psi-mi:cpxb_bacmb(display_long)|uniprotkb:cyp102A1(gene name)|psi-mi:cyp102A1(display_short)|uniprotkb:"Cytochrome P450(BM-3)"(gene name synonym)|uniprotkb:cyp102(gene name synonym)|uniprotkb:Cytochrome P450BM-3(gene name synonym)|uniprotkb:Fatty acid monooxygenase(gene name synonym)|uniprotkb:Flavocytochrome P450 BM3(gene name synonym)|uniprotkb:BG04_163(orf name)	psi-mi:"MI:0042"(electron paramagnetic resonance)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1348623(bacmb)|taxid:1348623(bacmb)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21445958|imex:IM-27046-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:5XHJ|rcsb pdb:5E7Y|rcsb pdb:4ZF6|rcsb pdb:4ZF8|rcsb pdb:4ZFA|rcsb pdb:4ZFB|rcsb pdb:5E78|rcsb pdb:5JQ2|rcsb pdb:5JQU|rcsb pdb:5JQV|rcsb pdb:5JTD|interpro:IPR023173|rcsb pdb:5XA3|ensemblbacteria:AJI21949(transcript)|ensemblbacteria:BG04_163(gene)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070330"(aromatase activity)|rcsb pdb:3WSP|rcsb pdb:5OG9|rcsb pdb:5ZLH|rcsb pdb:4RSN|rcsb pdb:6K3Q|rcsb pdb:6L1A|rcsb pdb:6L1B|rcsb pdb:1SMJ|rcsb pdb:4DUE|rcsb pdb:4DUB|rcsb pdb:3NPL|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|rcsb pdb:4HGI|rcsb pdb:4DUF|rcsb pdb:1JPZ|interpro:IPR001128(Cytochrome P450)|rcsb pdb:3DGI|rcsb pdb:2J1M|rcsb pdb:4DUC|rcsb pdb:3HF2|interpro:IPR023206|rcsb pdb:4DQK|rcsb pdb:1ZO9|rcsb pdb:3CBD|rcsb pdb:2IJ2|rcsb pdb:2UWH|rcsb pdb:1ZO4|rcsb pdb:4HGH|rcsb pdb:1JME|rcsb pdb:2X7Y|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|rcsb pdb:3KX4|rcsb pdb:1BVY|rcsb pdb:1YQP|rcsb pdb:2BMH|rcsb pdb:4DU2|rcsb pdb:3EKF|rcsb pdb:2HPD|interpro:IPR017927|rcsb pdb:3EKD|rcsb pdb:1SMI|rcsb pdb:4DUA|rcsb pdb:4DTY|rcsb pdb:3KX3|rcsb pdb:3M4V|rcsb pdb:4DUD|rcsb pdb:4HGF|rcsb pdb:4DTZ|rcsb pdb:1BU7|interpro:IPR001094(Flavodoxin-like)|rcsb pdb:2X80|rcsb pdb:1YQO|interpro:IPR017972|rcsb pdb:1FAH|rcsb pdb:3KX5|rcsb pdb:4DQL|rcsb pdb:1P0X|rcsb pdb:1P0V|rcsb pdb:3PSX|rcsb pdb:2IJ3|rcsb pdb:3EKB|interpro:IPR017938|rcsb pdb:2IJ4|rcsb pdb:4HGG|rcsb pdb:4HGJ|rcsb pdb:1P0W|rcsb pdb:3BEN|rcsb pdb:2J4S|rcsb pdb:1ZOA|rcsb pdb:2NNB|rcsb pdb:4DTW|rcsb pdb:1FAG|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|rcsb pdb:5DYP|rcsb pdb:5DYZ|rcsb pdb:5E9Z|rcsb pdb:4KPA|rcsb pdb:4KPB|rcsb pdb:4H23|rcsb pdb:4H24|rcsb pdb:4KEW|rcsb pdb:4KEY|rcsb pdb:4KF0|rcsb pdb:4KF2|rcsb pdb:4O4P|refseq:WP_034650526.1|interpro:IPR029039|rcsb pdb:4WG2|rcsb pdb:5B2U|rcsb pdb:5B2V|rcsb pdb:5B2W|rcsb pdb:5B2X|rcsb pdb:5B2Y|interpro:IPR036396|rcsb pdb:5UCW|interpro:IPR039261|rcsb pdb:5ZIS|rcsb pdb:6H1O|rcsb pdb:6H1S|rcsb pdb:6IAO|rcsb pdb:6HN8|rcsb pdb:6LY4|rcsb pdb:6JLV|rcsb pdb:6JMH|rcsb pdb:6JMW|rcsb pdb:6JO1|rcsb pdb:6JS8|rcsb pdb:6JVC|rcsb pdb:6JZS|rcsb pdb:6K58|rcsb pdb:6K9S|rcsb pdb:6K24	-	-	comment:mint	figure legend:Table S2, S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/05/29	2019/09/19	-	rogid:Oqu3y1hkk4FKpdRjfHQQkRz2qPQ1348623	-	false	-	mutation with no effect:83-83,88-88	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:9604"	uniprotkb:P14779	intact:EBI-21445074	intact:EBI-7701704|ensemblbacteria:AJI21949|intact:MINT-8313368|uniprotkb:A0A0B6AQ66|uniprotkb:Q9AE23	psi-mi:tioconazole(display_short)|psi-mi:"CHEBI:9604"(display_long)|intact:"(+-)-tioconazole"(synonym)|intact:"(+-)-1-(2,4-Dichloro-beta-((2-chloro-3-ethenyl)oxy)phenethyl)imidazole"(synonym)|intact:"(RS)-tioconazole"(synonym)|intact:"1-(2,4-Dichloro-(beta-(2-chloro-3-thenyl)oxy)phenethyl)imidazole"(synonym)|intact:rac-tioconazole(synonym)|intact:racemic tioconazole(synonym)|intact:tioconazol(synonym)|intact:tioconazole(synonym)|intact:tioconazolum(synonym)|intact:UK 20349(synonym)|intact:UK-20,349(synonym)|intact:Vagistat-1(synonym)|intact:"rac-1-{2-[(2-chloro-3-thienyl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole"(iupac name)	psi-mi:cpxb_bacmb(display_long)|uniprotkb:cyp102A1(gene name)|psi-mi:cyp102A1(display_short)|uniprotkb:"Cytochrome P450(BM-3)"(gene name synonym)|uniprotkb:cyp102(gene name synonym)|uniprotkb:Cytochrome P450BM-3(gene name synonym)|uniprotkb:Fatty acid monooxygenase(gene name synonym)|uniprotkb:Flavocytochrome P450 BM3(gene name synonym)|uniprotkb:BG04_163(orf name)	psi-mi:"MI:0042"(electron paramagnetic resonance)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1348623(bacmb)|taxid:1348623(bacmb)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21445967|imex:IM-27046-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:5XHJ|rcsb pdb:5E7Y|rcsb pdb:4ZF6|rcsb pdb:4ZF8|rcsb pdb:4ZFA|rcsb pdb:4ZFB|rcsb pdb:5E78|rcsb pdb:5JQ2|rcsb pdb:5JQU|rcsb pdb:5JQV|rcsb pdb:5JTD|interpro:IPR023173|rcsb pdb:5XA3|ensemblbacteria:AJI21949(transcript)|ensemblbacteria:BG04_163(gene)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070330"(aromatase activity)|rcsb pdb:3WSP|rcsb pdb:5OG9|rcsb pdb:5ZLH|rcsb pdb:4RSN|rcsb pdb:6K3Q|rcsb pdb:6L1A|rcsb pdb:6L1B|rcsb pdb:1SMJ|rcsb pdb:4DUE|rcsb pdb:4DUB|rcsb pdb:3NPL|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|rcsb pdb:4HGI|rcsb pdb:4DUF|rcsb pdb:1JPZ|interpro:IPR001128(Cytochrome P450)|rcsb pdb:3DGI|rcsb pdb:2J1M|rcsb pdb:4DUC|rcsb pdb:3HF2|interpro:IPR023206|rcsb pdb:4DQK|rcsb pdb:1ZO9|rcsb pdb:3CBD|rcsb pdb:2IJ2|rcsb pdb:2UWH|rcsb pdb:1ZO4|rcsb pdb:4HGH|rcsb pdb:1JME|rcsb pdb:2X7Y|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|rcsb pdb:3KX4|rcsb pdb:1BVY|rcsb pdb:1YQP|rcsb pdb:2BMH|rcsb pdb:4DU2|rcsb pdb:3EKF|rcsb pdb:2HPD|interpro:IPR017927|rcsb pdb:3EKD|rcsb pdb:1SMI|rcsb pdb:4DUA|rcsb pdb:4DTY|rcsb pdb:3KX3|rcsb pdb:3M4V|rcsb pdb:4DUD|rcsb pdb:4HGF|rcsb pdb:4DTZ|rcsb pdb:1BU7|interpro:IPR001094(Flavodoxin-like)|rcsb pdb:2X80|rcsb pdb:1YQO|interpro:IPR017972|rcsb pdb:1FAH|rcsb pdb:3KX5|rcsb pdb:4DQL|rcsb pdb:1P0X|rcsb pdb:1P0V|rcsb pdb:3PSX|rcsb pdb:2IJ3|rcsb pdb:3EKB|interpro:IPR017938|rcsb pdb:2IJ4|rcsb pdb:4HGG|rcsb pdb:4HGJ|rcsb pdb:1P0W|rcsb pdb:3BEN|rcsb pdb:2J4S|rcsb pdb:1ZOA|rcsb pdb:2NNB|rcsb pdb:4DTW|rcsb pdb:1FAG|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|rcsb pdb:5DYP|rcsb pdb:5DYZ|rcsb pdb:5E9Z|rcsb pdb:4KPA|rcsb pdb:4KPB|rcsb pdb:4H23|rcsb pdb:4H24|rcsb pdb:4KEW|rcsb pdb:4KEY|rcsb pdb:4KF0|rcsb pdb:4KF2|rcsb pdb:4O4P|refseq:WP_034650526.1|interpro:IPR029039|rcsb pdb:4WG2|rcsb pdb:5B2U|rcsb pdb:5B2V|rcsb pdb:5B2W|rcsb pdb:5B2X|rcsb pdb:5B2Y|interpro:IPR036396|rcsb pdb:5UCW|interpro:IPR039261|rcsb pdb:5ZIS|rcsb pdb:6H1O|rcsb pdb:6H1S|rcsb pdb:6IAO|rcsb pdb:6HN8|rcsb pdb:6LY4|rcsb pdb:6JLV|rcsb pdb:6JMH|rcsb pdb:6JMW|rcsb pdb:6JO1|rcsb pdb:6JS8|rcsb pdb:6JVC|rcsb pdb:6JZS|rcsb pdb:6K58|rcsb pdb:6K9S|rcsb pdb:6K24	-	-	comment:mint	figure legend:Table S2, S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/05/29	2019/09/19	-	rogid:Oqu3y1hkk4FKpdRjfHQQkRz2qPQ1348623	-	false	-	mutation with no effect:83-83,88-88	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:10023"	uniprotkb:P14779	intact:EBI-21445844|chebi:"CHEBI:127308"	intact:EBI-7701704|ensemblbacteria:AJI21949|intact:MINT-8313368|uniprotkb:A0A0B6AQ66|uniprotkb:Q9AE23	psi-mi:voriconazole(display_short)|psi-mi:"CHEBI:10023"(display_long)|intact:"(alphaR,betaS)-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol"(synonym)|intact:"(R-(R*,S*))-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol"(synonym)|intact:VCZ(synonym)|intact:Vfend(synonym)|intact:voriconazol(synonym)|intact:voriconazole(synonym)|intact:voriconazolum(synonym)|intact:"(2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol"(iupac name)	psi-mi:cpxb_bacmb(display_long)|uniprotkb:cyp102A1(gene name)|psi-mi:cyp102A1(display_short)|uniprotkb:"Cytochrome P450(BM-3)"(gene name synonym)|uniprotkb:cyp102(gene name synonym)|uniprotkb:Cytochrome P450BM-3(gene name synonym)|uniprotkb:Fatty acid monooxygenase(gene name synonym)|uniprotkb:Flavocytochrome P450 BM3(gene name synonym)|uniprotkb:BG04_163(orf name)	psi-mi:"MI:0042"(electron paramagnetic resonance)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1348623(bacmb)|taxid:1348623(bacmb)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21445976|imex:IM-27046-37	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:5XHJ|rcsb pdb:5E7Y|rcsb pdb:4ZF6|rcsb pdb:4ZF8|rcsb pdb:4ZFA|rcsb pdb:4ZFB|rcsb pdb:5E78|rcsb pdb:5JQ2|rcsb pdb:5JQU|rcsb pdb:5JQV|rcsb pdb:5JTD|interpro:IPR023173|rcsb pdb:5XA3|ensemblbacteria:AJI21949(transcript)|ensemblbacteria:BG04_163(gene)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070330"(aromatase activity)|rcsb pdb:3WSP|rcsb pdb:5OG9|rcsb pdb:5ZLH|rcsb pdb:4RSN|rcsb pdb:6K3Q|rcsb pdb:6L1A|rcsb pdb:6L1B|rcsb pdb:1SMJ|rcsb pdb:4DUE|rcsb pdb:4DUB|rcsb pdb:3NPL|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|rcsb pdb:4HGI|rcsb pdb:4DUF|rcsb pdb:1JPZ|interpro:IPR001128(Cytochrome P450)|rcsb pdb:3DGI|rcsb pdb:2J1M|rcsb pdb:4DUC|rcsb pdb:3HF2|interpro:IPR023206|rcsb pdb:4DQK|rcsb pdb:1ZO9|rcsb pdb:3CBD|rcsb pdb:2IJ2|rcsb pdb:2UWH|rcsb pdb:1ZO4|rcsb pdb:4HGH|rcsb pdb:1JME|rcsb pdb:2X7Y|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|rcsb pdb:3KX4|rcsb pdb:1BVY|rcsb pdb:1YQP|rcsb pdb:2BMH|rcsb pdb:4DU2|rcsb pdb:3EKF|rcsb pdb:2HPD|interpro:IPR017927|rcsb pdb:3EKD|rcsb pdb:1SMI|rcsb pdb:4DUA|rcsb pdb:4DTY|rcsb pdb:3KX3|rcsb pdb:3M4V|rcsb pdb:4DUD|rcsb pdb:4HGF|rcsb pdb:4DTZ|rcsb pdb:1BU7|interpro:IPR001094(Flavodoxin-like)|rcsb pdb:2X80|rcsb pdb:1YQO|interpro:IPR017972|rcsb pdb:1FAH|rcsb pdb:3KX5|rcsb pdb:4DQL|rcsb pdb:1P0X|rcsb pdb:1P0V|rcsb pdb:3PSX|rcsb pdb:2IJ3|rcsb pdb:3EKB|interpro:IPR017938|rcsb pdb:2IJ4|rcsb pdb:4HGG|rcsb pdb:4HGJ|rcsb pdb:1P0W|rcsb pdb:3BEN|rcsb pdb:2J4S|rcsb pdb:1ZOA|rcsb pdb:2NNB|rcsb pdb:4DTW|rcsb pdb:1FAG|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|rcsb pdb:5DYP|rcsb pdb:5DYZ|rcsb pdb:5E9Z|rcsb pdb:4KPA|rcsb pdb:4KPB|rcsb pdb:4H23|rcsb pdb:4H24|rcsb pdb:4KEW|rcsb pdb:4KEY|rcsb pdb:4KF0|rcsb pdb:4KF2|rcsb pdb:4O4P|refseq:WP_034650526.1|interpro:IPR029039|rcsb pdb:4WG2|rcsb pdb:5B2U|rcsb pdb:5B2V|rcsb pdb:5B2W|rcsb pdb:5B2X|rcsb pdb:5B2Y|interpro:IPR036396|rcsb pdb:5UCW|interpro:IPR039261|rcsb pdb:5ZIS|rcsb pdb:6H1O|rcsb pdb:6H1S|rcsb pdb:6IAO|rcsb pdb:6HN8|rcsb pdb:6LY4|rcsb pdb:6JLV|rcsb pdb:6JMH|rcsb pdb:6JMW|rcsb pdb:6JO1|rcsb pdb:6JS8|rcsb pdb:6JVC|rcsb pdb:6JZS|rcsb pdb:6K58|rcsb pdb:6K9S|rcsb pdb:6K24	-	-	comment:mint	figure legend:Table S2, S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/05/29	2019/09/19	-	rogid:Oqu3y1hkk4FKpdRjfHQQkRz2qPQ1348623	-	false	-	mutation with no effect:83-83,88-88	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:3764"	uniprotkb:A0A1Q8UP87	intact:EBI-21444840	intact:EBI-21444754|ensemblbacteria:OLO37644	psi-mi:clotrimazole(display_short)|psi-mi:"CHEBI:3764"(display_long)|intact:"1-((2-Chlorophenyl)diphenylmethyl)-1H-imidazole"(synonym)|intact:"1-(alpha-(2-Chlorophenyl)benzhydryl)imidazole"(synonym)|intact:"1-(o-Chloro-alpha,alpha-diphenylbenzyl)imidazole"(synonym)|intact:"1-(o-Chlorotrityl)imidazole"(synonym)|intact:Clotrimazole(synonym)|intact:"Lotrimin (TN)"(synonym)|intact:"Mycelex (TN)"(synonym)|intact:"1-[(2-chlorophenyl)(diphenyl)methyl]-1H-imidazole"(iupac name)	psi-mi:a0a1q8up87_bacme(display_long)|uniprotkb:BTA37_15100(orf name)	psi-mi:"MI:0114"(x-ray crystallography)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1404(bacme)|taxid:1404(Bacillus megaterium)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21445994|pdbe:6H1T|imex:IM-27046-55	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:WP_075421014.1|rcsb pdb:6H1T|interpro:IPR023206|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR036396|interpro:IPR017927|interpro:IPR001094(Flavodoxin-like)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR029039|interpro:IPR039261|interpro:IPR023173|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR017938|ensemblbacteria:BTA37_15100(gene)|ensemblbacteria:OLO37644(transcript)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0010181"(FMN binding)|go:"GO:0020037"(heme binding)|go:"GO:0070330"(aromatase activity)	-	-	-	figure legend:Table S1|3d-r-factors:"Rwork/Rfree: 0.170/0.213"|3d-resolution:"Resolution (Å): 2.08"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/05/29	2019/09/19	-	rogid:9loc7Kv0DCz2UdBGG1f2gjvPK/E1404	-	false	-	sufficient binding region:2-459	4	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:26355"	uniprotkb:A0A1Q8UP87	intact:EBI-1225103	intact:EBI-21444754|ensemblbacteria:OLO37644	psi-mi:heme b(display_short)|psi-mi:"CHEBI:26355"(display_long)	psi-mi:a0a1q8up87_bacme(display_long)|uniprotkb:BTA37_15100(orf name)	psi-mi:"MI:0114"(x-ray crystallography)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1404(bacme)|taxid:1404(Bacillus megaterium)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21445994|pdbe:6H1T|imex:IM-27046-55	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0682"(cofactor)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:WP_075421014.1|rcsb pdb:6H1T|interpro:IPR023206|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR036396|interpro:IPR017927|interpro:IPR001094(Flavodoxin-like)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR029039|interpro:IPR039261|interpro:IPR023173|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR017938|ensemblbacteria:BTA37_15100(gene)|ensemblbacteria:OLO37644(transcript)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0010181"(FMN binding)|go:"GO:0020037"(heme binding)|go:"GO:0070330"(aromatase activity)	-	-	-	figure legend:Table S1|3d-r-factors:"Rwork/Rfree: 0.170/0.213"|3d-resolution:"Resolution (Å): 2.08"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/05/29	2019/09/19	-	rogid:9loc7Kv0DCz2UdBGG1f2gjvPK/E1404	-	false	-	sufficient binding region:2-459	4	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:46081"	uniprotkb:P14779	intact:EBI-21444880|chebi:"CHEBI:46079"|chebi:"CHEBI:5099"	intact:EBI-7701704|ensemblbacteria:AJI21949|intact:MINT-8313368|uniprotkb:A0A0B6AQ66|uniprotkb:Q9AE23	psi-mi:fluconazole(display_short)|psi-mi:"CHEBI:46081"(display_long)|intact:"2,4-difluoro-alpha,alpha-bis(1H-1,2,4-triazol-1-ylmethyl)benzyl alcohol"(synonym)|intact:"2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL"(synonym)|intact:Biozole(synonym)|intact:Diflucan(synonym)|intact:Elazor(synonym)|intact:fluconazol(synonym)|intact:fluconazole(synonym)|intact:fluconazolum(synonym)|intact:Triflucan(synonym)|intact:"2-(2,4-difluorophenyl)-1,3-bis-(1H-1,2,4-triazol-1-yl)propan-2-ol"(iupac name)	psi-mi:cpxb_bacmb(display_long)|uniprotkb:cyp102A1(gene name)|psi-mi:cyp102A1(display_short)|uniprotkb:"Cytochrome P450(BM-3)"(gene name synonym)|uniprotkb:cyp102(gene name synonym)|uniprotkb:Cytochrome P450BM-3(gene name synonym)|uniprotkb:Fatty acid monooxygenase(gene name synonym)|uniprotkb:Flavocytochrome P450 BM3(gene name synonym)|uniprotkb:BG04_163(orf name)	psi-mi:"MI:0114"(x-ray crystallography)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1348623(bacmb)|taxid:1348623(bacmb)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21446001|pdbe:6H1S|imex:IM-27046-57	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0682"(cofactor)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:5XHJ|rcsb pdb:5E7Y|rcsb pdb:4ZF6|rcsb pdb:4ZF8|rcsb pdb:4ZFA|rcsb pdb:4ZFB|rcsb pdb:5E78|rcsb pdb:5JQ2|rcsb pdb:5JQU|rcsb pdb:5JQV|rcsb pdb:5JTD|interpro:IPR023173|rcsb pdb:5XA3|ensemblbacteria:AJI21949(transcript)|ensemblbacteria:BG04_163(gene)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070330"(aromatase activity)|rcsb pdb:3WSP|rcsb pdb:5OG9|rcsb pdb:5ZLH|rcsb pdb:4RSN|rcsb pdb:6K3Q|rcsb pdb:6L1A|rcsb pdb:6L1B|rcsb pdb:1SMJ|rcsb pdb:4DUE|rcsb pdb:4DUB|rcsb pdb:3NPL|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|rcsb pdb:4HGI|rcsb pdb:4DUF|rcsb pdb:1JPZ|interpro:IPR001128(Cytochrome P450)|rcsb pdb:3DGI|rcsb pdb:2J1M|rcsb pdb:4DUC|rcsb pdb:3HF2|interpro:IPR023206|rcsb pdb:4DQK|rcsb pdb:1ZO9|rcsb pdb:3CBD|rcsb pdb:2IJ2|rcsb pdb:2UWH|rcsb pdb:1ZO4|rcsb pdb:4HGH|rcsb pdb:1JME|rcsb pdb:2X7Y|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|rcsb pdb:3KX4|rcsb pdb:1BVY|rcsb pdb:1YQP|rcsb pdb:2BMH|rcsb pdb:4DU2|rcsb pdb:3EKF|rcsb pdb:2HPD|interpro:IPR017927|rcsb pdb:3EKD|rcsb pdb:1SMI|rcsb pdb:4DUA|rcsb pdb:4DTY|rcsb pdb:3KX3|rcsb pdb:3M4V|rcsb pdb:4DUD|rcsb pdb:4HGF|rcsb pdb:4DTZ|rcsb pdb:1BU7|interpro:IPR001094(Flavodoxin-like)|rcsb pdb:2X80|rcsb pdb:1YQO|interpro:IPR017972|rcsb pdb:1FAH|rcsb pdb:3KX5|rcsb pdb:4DQL|rcsb pdb:1P0X|rcsb pdb:1P0V|rcsb pdb:3PSX|rcsb pdb:2IJ3|rcsb pdb:3EKB|interpro:IPR017938|rcsb pdb:2IJ4|rcsb pdb:4HGG|rcsb pdb:4HGJ|rcsb pdb:1P0W|rcsb pdb:3BEN|rcsb pdb:2J4S|rcsb pdb:1ZOA|rcsb pdb:2NNB|rcsb pdb:4DTW|rcsb pdb:1FAG|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|rcsb pdb:5DYP|rcsb pdb:5DYZ|rcsb pdb:5E9Z|rcsb pdb:4KPA|rcsb pdb:4KPB|rcsb pdb:4H23|rcsb pdb:4H24|rcsb pdb:4KEW|rcsb pdb:4KEY|rcsb pdb:4KF0|rcsb pdb:4KF2|rcsb pdb:4O4P|refseq:WP_034650526.1|interpro:IPR029039|rcsb pdb:4WG2|rcsb pdb:5B2U|rcsb pdb:5B2V|rcsb pdb:5B2W|rcsb pdb:5B2X|rcsb pdb:5B2Y|interpro:IPR036396|rcsb pdb:5UCW|interpro:IPR039261|rcsb pdb:5ZIS|rcsb pdb:6H1O|rcsb pdb:6H1S|rcsb pdb:6IAO|rcsb pdb:6HN8|rcsb pdb:6LY4|rcsb pdb:6JLV|rcsb pdb:6JMH|rcsb pdb:6JMW|rcsb pdb:6JO1|rcsb pdb:6JS8|rcsb pdb:6JVC|rcsb pdb:6JZS|rcsb pdb:6K58|rcsb pdb:6K9S|rcsb pdb:6K24	-	-	comment:mint	figure legend:Table S1|3d-r-factors:"Rwork/Rfree: 0.162/0.200"|3d-resolution:"Resolution (Å): 1.95"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/05/29	2019/09/19	-	rogid:Oqu3y1hkk4FKpdRjfHQQkRz2qPQ1348623	-	false	-	sufficient binding region:2-458	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:26355"	uniprotkb:P14779	intact:EBI-1225103	intact:EBI-7701704|ensemblbacteria:AJI21949|intact:MINT-8313368|uniprotkb:A0A0B6AQ66|uniprotkb:Q9AE23	psi-mi:heme b(display_short)|psi-mi:"CHEBI:26355"(display_long)	psi-mi:cpxb_bacmb(display_long)|uniprotkb:cyp102A1(gene name)|psi-mi:cyp102A1(display_short)|uniprotkb:"Cytochrome P450(BM-3)"(gene name synonym)|uniprotkb:cyp102(gene name synonym)|uniprotkb:Cytochrome P450BM-3(gene name synonym)|uniprotkb:Fatty acid monooxygenase(gene name synonym)|uniprotkb:Flavocytochrome P450 BM3(gene name synonym)|uniprotkb:BG04_163(orf name)	psi-mi:"MI:0114"(x-ray crystallography)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1348623(bacmb)|taxid:1348623(bacmb)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21446001|pdbe:6H1S|imex:IM-27046-57	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0682"(cofactor)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:5XHJ|rcsb pdb:5E7Y|rcsb pdb:4ZF6|rcsb pdb:4ZF8|rcsb pdb:4ZFA|rcsb pdb:4ZFB|rcsb pdb:5E78|rcsb pdb:5JQ2|rcsb pdb:5JQU|rcsb pdb:5JQV|rcsb pdb:5JTD|interpro:IPR023173|rcsb pdb:5XA3|ensemblbacteria:AJI21949(transcript)|ensemblbacteria:BG04_163(gene)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070330"(aromatase activity)|rcsb pdb:3WSP|rcsb pdb:5OG9|rcsb pdb:5ZLH|rcsb pdb:4RSN|rcsb pdb:6K3Q|rcsb pdb:6L1A|rcsb pdb:6L1B|rcsb pdb:1SMJ|rcsb pdb:4DUE|rcsb pdb:4DUB|rcsb pdb:3NPL|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|rcsb pdb:4HGI|rcsb pdb:4DUF|rcsb pdb:1JPZ|interpro:IPR001128(Cytochrome P450)|rcsb pdb:3DGI|rcsb pdb:2J1M|rcsb pdb:4DUC|rcsb pdb:3HF2|interpro:IPR023206|rcsb pdb:4DQK|rcsb pdb:1ZO9|rcsb pdb:3CBD|rcsb pdb:2IJ2|rcsb pdb:2UWH|rcsb pdb:1ZO4|rcsb pdb:4HGH|rcsb pdb:1JME|rcsb pdb:2X7Y|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|rcsb pdb:3KX4|rcsb pdb:1BVY|rcsb pdb:1YQP|rcsb pdb:2BMH|rcsb pdb:4DU2|rcsb pdb:3EKF|rcsb pdb:2HPD|interpro:IPR017927|rcsb pdb:3EKD|rcsb pdb:1SMI|rcsb pdb:4DUA|rcsb pdb:4DTY|rcsb pdb:3KX3|rcsb pdb:3M4V|rcsb pdb:4DUD|rcsb pdb:4HGF|rcsb pdb:4DTZ|rcsb pdb:1BU7|interpro:IPR001094(Flavodoxin-like)|rcsb pdb:2X80|rcsb pdb:1YQO|interpro:IPR017972|rcsb pdb:1FAH|rcsb pdb:3KX5|rcsb pdb:4DQL|rcsb pdb:1P0X|rcsb pdb:1P0V|rcsb pdb:3PSX|rcsb pdb:2IJ3|rcsb pdb:3EKB|interpro:IPR017938|rcsb pdb:2IJ4|rcsb pdb:4HGG|rcsb pdb:4HGJ|rcsb pdb:1P0W|rcsb pdb:3BEN|rcsb pdb:2J4S|rcsb pdb:1ZOA|rcsb pdb:2NNB|rcsb pdb:4DTW|rcsb pdb:1FAG|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|rcsb pdb:5DYP|rcsb pdb:5DYZ|rcsb pdb:5E9Z|rcsb pdb:4KPA|rcsb pdb:4KPB|rcsb pdb:4H23|rcsb pdb:4H24|rcsb pdb:4KEW|rcsb pdb:4KEY|rcsb pdb:4KF0|rcsb pdb:4KF2|rcsb pdb:4O4P|refseq:WP_034650526.1|interpro:IPR029039|rcsb pdb:4WG2|rcsb pdb:5B2U|rcsb pdb:5B2V|rcsb pdb:5B2W|rcsb pdb:5B2X|rcsb pdb:5B2Y|interpro:IPR036396|rcsb pdb:5UCW|interpro:IPR039261|rcsb pdb:5ZIS|rcsb pdb:6H1O|rcsb pdb:6H1S|rcsb pdb:6IAO|rcsb pdb:6HN8|rcsb pdb:6LY4|rcsb pdb:6JLV|rcsb pdb:6JMH|rcsb pdb:6JMW|rcsb pdb:6JO1|rcsb pdb:6JS8|rcsb pdb:6JVC|rcsb pdb:6JZS|rcsb pdb:6K58|rcsb pdb:6K9S|rcsb pdb:6K24	-	-	comment:mint	figure legend:Table S1|3d-r-factors:"Rwork/Rfree: 0.162/0.200"|3d-resolution:"Resolution (Å): 1.95"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/05/29	2019/09/19	-	rogid:Oqu3y1hkk4FKpdRjfHQQkRz2qPQ1348623	-	false	-	sufficient binding region:2-458	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:26355"	uniprotkb:F2Q7T0	intact:EBI-1225103	intact:EBI-22031055	psi-mi:heme b(display_short)|psi-mi:"CHEBI:26355"(display_long)	psi-mi:f2q7t0_bacme(display_long)	psi-mi:"MI:0114"(x-ray crystallography)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1404(bacme)|taxid:1404(Bacillus megaterium)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21446008|pdbe:6H1L|imex:IM-27046-39	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0682"(cofactor)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:6H1L|interpro:IPR023206|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR036396|interpro:IPR017927|interpro:IPR001094(Flavodoxin-like)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR029039|interpro:IPR039261|interpro:IPR023173|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR017938|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0010181"(FMN binding)|go:"GO:0020037"(heme binding)|go:"GO:0070330"(aromatase activity)	-	-	-	figure legend:Table S1|3d-r-factors:"Rwork/Rfree: 0.189/0.215"|3d-resolution:"Resolution (Å): 1.97"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/05/29	2019/09/19	-	rogid:BpzVP0rk8rw04Q3nTq1ikA49VT41404	-	false	-	sufficient binding region:2-458	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:9604"	uniprotkb:F2Q7T0	intact:EBI-21445074	intact:EBI-22031055	psi-mi:tioconazole(display_short)|psi-mi:"CHEBI:9604"(display_long)|intact:"(+-)-tioconazole"(synonym)|intact:"(+-)-1-(2,4-Dichloro-beta-((2-chloro-3-ethenyl)oxy)phenethyl)imidazole"(synonym)|intact:"(RS)-tioconazole"(synonym)|intact:"1-(2,4-Dichloro-(beta-(2-chloro-3-thenyl)oxy)phenethyl)imidazole"(synonym)|intact:rac-tioconazole(synonym)|intact:racemic tioconazole(synonym)|intact:tioconazol(synonym)|intact:tioconazole(synonym)|intact:tioconazolum(synonym)|intact:UK 20349(synonym)|intact:UK-20,349(synonym)|intact:Vagistat-1(synonym)|intact:"rac-1-{2-[(2-chloro-3-thienyl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole"(iupac name)	psi-mi:f2q7t0_bacme(display_long)	psi-mi:"MI:0114"(x-ray crystallography)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1404(bacme)|taxid:1404(Bacillus megaterium)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21446008|pdbe:6H1L|imex:IM-27046-39	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:6H1L|interpro:IPR023206|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR036396|interpro:IPR017927|interpro:IPR001094(Flavodoxin-like)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR029039|interpro:IPR039261|interpro:IPR023173|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR017938|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0010181"(FMN binding)|go:"GO:0020037"(heme binding)|go:"GO:0070330"(aromatase activity)	-	-	-	figure legend:Table S1|3d-r-factors:"Rwork/Rfree: 0.189/0.215"|3d-resolution:"Resolution (Å): 1.97"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/05/29	2019/09/19	-	rogid:BpzVP0rk8rw04Q3nTq1ikA49VT41404	-	false	-	sufficient binding region:2-458	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:26355"	uniprotkb:P14779	intact:EBI-1225103	intact:EBI-7701704|ensemblbacteria:AJI21949|intact:MINT-8313368|uniprotkb:A0A0B6AQ66|uniprotkb:Q9AE23	psi-mi:heme b(display_short)|psi-mi:"CHEBI:26355"(display_long)	psi-mi:cpxb_bacmb(display_long)|uniprotkb:cyp102A1(gene name)|psi-mi:cyp102A1(display_short)|uniprotkb:"Cytochrome P450(BM-3)"(gene name synonym)|uniprotkb:cyp102(gene name synonym)|uniprotkb:Cytochrome P450BM-3(gene name synonym)|uniprotkb:Fatty acid monooxygenase(gene name synonym)|uniprotkb:Flavocytochrome P450 BM3(gene name synonym)|uniprotkb:BG04_163(orf name)	psi-mi:"MI:0114"(x-ray crystallography)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1348623(bacmb)|taxid:1348623(bacmb)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21446015|pdbe:6H1O|imex:IM-27046-59	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0682"(cofactor)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:5XHJ|rcsb pdb:5E7Y|rcsb pdb:4ZF6|rcsb pdb:4ZF8|rcsb pdb:4ZFA|rcsb pdb:4ZFB|rcsb pdb:5E78|rcsb pdb:5JQ2|rcsb pdb:5JQU|rcsb pdb:5JQV|rcsb pdb:5JTD|interpro:IPR023173|rcsb pdb:5XA3|ensemblbacteria:AJI21949(transcript)|ensemblbacteria:BG04_163(gene)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070330"(aromatase activity)|rcsb pdb:3WSP|rcsb pdb:5OG9|rcsb pdb:5ZLH|rcsb pdb:4RSN|rcsb pdb:6K3Q|rcsb pdb:6L1A|rcsb pdb:6L1B|rcsb pdb:1SMJ|rcsb pdb:4DUE|rcsb pdb:4DUB|rcsb pdb:3NPL|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|rcsb pdb:4HGI|rcsb pdb:4DUF|rcsb pdb:1JPZ|interpro:IPR001128(Cytochrome P450)|rcsb pdb:3DGI|rcsb pdb:2J1M|rcsb pdb:4DUC|rcsb pdb:3HF2|interpro:IPR023206|rcsb pdb:4DQK|rcsb pdb:1ZO9|rcsb pdb:3CBD|rcsb pdb:2IJ2|rcsb pdb:2UWH|rcsb pdb:1ZO4|rcsb pdb:4HGH|rcsb pdb:1JME|rcsb pdb:2X7Y|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|rcsb pdb:3KX4|rcsb pdb:1BVY|rcsb pdb:1YQP|rcsb pdb:2BMH|rcsb pdb:4DU2|rcsb pdb:3EKF|rcsb pdb:2HPD|interpro:IPR017927|rcsb pdb:3EKD|rcsb pdb:1SMI|rcsb pdb:4DUA|rcsb pdb:4DTY|rcsb pdb:3KX3|rcsb pdb:3M4V|rcsb pdb:4DUD|rcsb pdb:4HGF|rcsb pdb:4DTZ|rcsb pdb:1BU7|interpro:IPR001094(Flavodoxin-like)|rcsb pdb:2X80|rcsb pdb:1YQO|interpro:IPR017972|rcsb pdb:1FAH|rcsb pdb:3KX5|rcsb pdb:4DQL|rcsb pdb:1P0X|rcsb pdb:1P0V|rcsb pdb:3PSX|rcsb pdb:2IJ3|rcsb pdb:3EKB|interpro:IPR017938|rcsb pdb:2IJ4|rcsb pdb:4HGG|rcsb pdb:4HGJ|rcsb pdb:1P0W|rcsb pdb:3BEN|rcsb pdb:2J4S|rcsb pdb:1ZOA|rcsb pdb:2NNB|rcsb pdb:4DTW|rcsb pdb:1FAG|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|rcsb pdb:5DYP|rcsb pdb:5DYZ|rcsb pdb:5E9Z|rcsb pdb:4KPA|rcsb pdb:4KPB|rcsb pdb:4H23|rcsb pdb:4H24|rcsb pdb:4KEW|rcsb pdb:4KEY|rcsb pdb:4KF0|rcsb pdb:4KF2|rcsb pdb:4O4P|refseq:WP_034650526.1|interpro:IPR029039|rcsb pdb:4WG2|rcsb pdb:5B2U|rcsb pdb:5B2V|rcsb pdb:5B2W|rcsb pdb:5B2X|rcsb pdb:5B2Y|interpro:IPR036396|rcsb pdb:5UCW|interpro:IPR039261|rcsb pdb:5ZIS|rcsb pdb:6H1O|rcsb pdb:6H1S|rcsb pdb:6IAO|rcsb pdb:6HN8|rcsb pdb:6LY4|rcsb pdb:6JLV|rcsb pdb:6JMH|rcsb pdb:6JMW|rcsb pdb:6JO1|rcsb pdb:6JS8|rcsb pdb:6JVC|rcsb pdb:6JZS|rcsb pdb:6K58|rcsb pdb:6K9S|rcsb pdb:6K24	-	-	comment:mint	figure legend:Table S1|3d-r-factors:"Rwork/Rfree: 0.159/0.199"|3d-resolution:"Resolution (Å): 1.73"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/05/29	2019/09/19	-	rogid:Oqu3y1hkk4FKpdRjfHQQkRz2qPQ1348623	-	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:10023"	uniprotkb:P14779	intact:EBI-21445844|chebi:"CHEBI:127308"	intact:EBI-7701704|ensemblbacteria:AJI21949|intact:MINT-8313368|uniprotkb:A0A0B6AQ66|uniprotkb:Q9AE23	psi-mi:voriconazole(display_short)|psi-mi:"CHEBI:10023"(display_long)|intact:"(alphaR,betaS)-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol"(synonym)|intact:"(R-(R*,S*))-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol"(synonym)|intact:VCZ(synonym)|intact:Vfend(synonym)|intact:voriconazol(synonym)|intact:voriconazole(synonym)|intact:voriconazolum(synonym)|intact:"(2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol"(iupac name)	psi-mi:cpxb_bacmb(display_long)|uniprotkb:cyp102A1(gene name)|psi-mi:cyp102A1(display_short)|uniprotkb:"Cytochrome P450(BM-3)"(gene name synonym)|uniprotkb:cyp102(gene name synonym)|uniprotkb:Cytochrome P450BM-3(gene name synonym)|uniprotkb:Fatty acid monooxygenase(gene name synonym)|uniprotkb:Flavocytochrome P450 BM3(gene name synonym)|uniprotkb:BG04_163(orf name)	psi-mi:"MI:0114"(x-ray crystallography)	Jeffreys et al. (2019)	pubmed:30733479|imex:IM-27046	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:1348623(bacmb)|taxid:1348623(bacmb)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21446015|pdbe:6H1O|imex:IM-27046-59	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:5XHJ|rcsb pdb:5E7Y|rcsb pdb:4ZF6|rcsb pdb:4ZF8|rcsb pdb:4ZFA|rcsb pdb:4ZFB|rcsb pdb:5E78|rcsb pdb:5JQ2|rcsb pdb:5JQU|rcsb pdb:5JQV|rcsb pdb:5JTD|interpro:IPR023173|rcsb pdb:5XA3|ensemblbacteria:AJI21949(transcript)|ensemblbacteria:BG04_163(gene)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008152"(metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070330"(aromatase activity)|rcsb pdb:3WSP|rcsb pdb:5OG9|rcsb pdb:5ZLH|rcsb pdb:4RSN|rcsb pdb:6K3Q|rcsb pdb:6L1A|rcsb pdb:6L1B|rcsb pdb:1SMJ|rcsb pdb:4DUE|rcsb pdb:4DUB|rcsb pdb:3NPL|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|rcsb pdb:4HGI|rcsb pdb:4DUF|rcsb pdb:1JPZ|interpro:IPR001128(Cytochrome P450)|rcsb pdb:3DGI|rcsb pdb:2J1M|rcsb pdb:4DUC|rcsb pdb:3HF2|interpro:IPR023206|rcsb pdb:4DQK|rcsb pdb:1ZO9|rcsb pdb:3CBD|rcsb pdb:2IJ2|rcsb pdb:2UWH|rcsb pdb:1ZO4|rcsb pdb:4HGH|rcsb pdb:1JME|rcsb pdb:2X7Y|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|rcsb pdb:3KX4|rcsb pdb:1BVY|rcsb pdb:1YQP|rcsb pdb:2BMH|rcsb pdb:4DU2|rcsb pdb:3EKF|rcsb pdb:2HPD|interpro:IPR017927|rcsb pdb:3EKD|rcsb pdb:1SMI|rcsb pdb:4DUA|rcsb pdb:4DTY|rcsb pdb:3KX3|rcsb pdb:3M4V|rcsb pdb:4DUD|rcsb pdb:4HGF|rcsb pdb:4DTZ|rcsb pdb:1BU7|interpro:IPR001094(Flavodoxin-like)|rcsb pdb:2X80|rcsb pdb:1YQO|interpro:IPR017972|rcsb pdb:1FAH|rcsb pdb:3KX5|rcsb pdb:4DQL|rcsb pdb:1P0X|rcsb pdb:1P0V|rcsb pdb:3PSX|rcsb pdb:2IJ3|rcsb pdb:3EKB|interpro:IPR017938|rcsb pdb:2IJ4|rcsb pdb:4HGG|rcsb pdb:4HGJ|rcsb pdb:1P0W|rcsb pdb:3BEN|rcsb pdb:2J4S|rcsb pdb:1ZOA|rcsb pdb:2NNB|rcsb pdb:4DTW|rcsb pdb:1FAG|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|rcsb pdb:5DYP|rcsb pdb:5DYZ|rcsb pdb:5E9Z|rcsb pdb:4KPA|rcsb pdb:4KPB|rcsb pdb:4H23|rcsb pdb:4H24|rcsb pdb:4KEW|rcsb pdb:4KEY|rcsb pdb:4KF0|rcsb pdb:4KF2|rcsb pdb:4O4P|refseq:WP_034650526.1|interpro:IPR029039|rcsb pdb:4WG2|rcsb pdb:5B2U|rcsb pdb:5B2V|rcsb pdb:5B2W|rcsb pdb:5B2X|rcsb pdb:5B2Y|interpro:IPR036396|rcsb pdb:5UCW|interpro:IPR039261|rcsb pdb:5ZIS|rcsb pdb:6H1O|rcsb pdb:6H1S|rcsb pdb:6IAO|rcsb pdb:6HN8|rcsb pdb:6LY4|rcsb pdb:6JLV|rcsb pdb:6JMH|rcsb pdb:6JMW|rcsb pdb:6JO1|rcsb pdb:6JS8|rcsb pdb:6JVC|rcsb pdb:6JZS|rcsb pdb:6K58|rcsb pdb:6K9S|rcsb pdb:6K24	-	-	comment:mint	figure legend:Table S1|3d-r-factors:"Rwork/Rfree: 0.159/0.199"|3d-resolution:"Resolution (Å): 1.73"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/05/29	2019/09/19	-	rogid:Oqu3y1hkk4FKpdRjfHQQkRz2qPQ1348623	-	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)