#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P41594 uniprotkb:P41594 intact:EBI-6595175|ensembl:ENSP00000306138|uniprotkb:Q6J164 intact:EBI-6595175|ensembl:ENSP00000306138|uniprotkb:Q6J164 psi-mi:grm5_human(display_long)|uniprotkb:GRM5(gene name)|psi-mi:GRM5(display_short)|uniprotkb:GPRC1E(gene name synonym)|uniprotkb:MGLUR5(gene name synonym) psi-mi:grm5_human(display_long)|uniprotkb:GRM5(gene name)|psi-mi:GRM5(display_short)|uniprotkb:GPRC1E(gene name synonym)|uniprotkb:MGLUR5(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Koehl et al. (2019) pubmed:30675062|imex:IM-27213 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-21195090|emdb:EMD-0346|wwpdb:6N51|emdb:EMD-0345|wwpdb:6N52|emdb:EMD-0347|imex:IM-27213-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000168959(gene)|ensembl:ENST00000305447(transcript)|go:"GO:0001640"(adenylate cyclase inhibiting G protein-coupled glutamate receptor activity)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006417"(regulation of translation)|go:"GO:0006448"(regulation of translational elongation)|go:"GO:0007206"(phospholipase C-activating G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0030296"(protein tyrosine kinase activator activity)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050808"(synapse organization)|go:"GO:0050890"(cognition)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090647"(modulation of age-related behavioral decline)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:0099530"(G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential)|go:"GO:0099553"(trans-synaptic signaling by endocannabinoid, modulating synaptic transmission)|go:"GO:0099583"(neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:1902938"(regulation of intracellular calcium activated chloride channel activity)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000162(GPCR, family 3, metabotropic glutamate receptor)|interpro:IPR000202(GPCR, family 3, metabotropic glutamate receptor 5)|interpro:IPR000337(GPCR, family 3)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR011500(GPCR, family 3, nine cysteines region)|interpro:IPR017978|interpro:IPR017979|interpro:IPR019588|interpro:IPR028082|interpro:IPR038550|rcsb pdb:3LMK|rcsb pdb:4OO9|rcsb pdb:5CGC|rcsb pdb:5CGD|rcsb pdb:6N4X|rcsb pdb:6N4Y|rcsb pdb:6N50|rcsb pdb:6N51|rcsb pdb:6N52|reactome:R-HSA-416476|reactome:R-HSA-420499|reactome:R-HSA-6794361|refseq:XP_011541094.1|refseq:NP_000833.1|refseq:NP_001137303.1|refseq:XP_006718891.1|refseq:XP_016873116.1 ensembl:ENSG00000168959(gene)|ensembl:ENST00000305447(transcript)|go:"GO:0001640"(adenylate cyclase inhibiting G protein-coupled glutamate receptor activity)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006417"(regulation of translation)|go:"GO:0006448"(regulation of translational elongation)|go:"GO:0007206"(phospholipase C-activating G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0030296"(protein tyrosine kinase activator activity)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050808"(synapse organization)|go:"GO:0050890"(cognition)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090647"(modulation of age-related behavioral decline)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:0099530"(G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential)|go:"GO:0099553"(trans-synaptic signaling by endocannabinoid, modulating synaptic transmission)|go:"GO:0099583"(neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:1902938"(regulation of intracellular calcium activated chloride channel activity)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000162(GPCR, family 3, metabotropic glutamate receptor)|interpro:IPR000202(GPCR, family 3, metabotropic glutamate receptor 5)|interpro:IPR000337(GPCR, family 3)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR011500(GPCR, family 3, nine cysteines region)|interpro:IPR017978|interpro:IPR017979|interpro:IPR019588|interpro:IPR028082|interpro:IPR038550|rcsb pdb:3LMK|rcsb pdb:4OO9|rcsb pdb:5CGC|rcsb pdb:5CGD|rcsb pdb:6N4X|rcsb pdb:6N4Y|rcsb pdb:6N50|rcsb pdb:6N51|rcsb pdb:6N52|reactome:R-HSA-416476|reactome:R-HSA-420499|reactome:R-HSA-6794361|refseq:XP_011541094.1|refseq:NP_000833.1|refseq:NP_001137303.1|refseq:XP_006718891.1|refseq:XP_016873116.1 - - - figure legend:Fig 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr)|taxid:7108("Spodoptera frugiperda (Fall armyworm)") - 2019/02/07 2019/07/13 rogid:/kz6DJ8xJVDQPX6jEYoTGxmAMsw9606 rogid:/kz6DJ8xJVDQPX6jEYoTGxmAMsw9606 rigid:6rXInvtNd52SJlKpBCsHEAaUpFY false ha tag:n-n|flag tag:n-n|binding-associated region:21-865 ha tag:n-n|flag tag:n-n|binding-associated region:21-865 2 0 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:P41594 uniprotkb:P41594 intact:EBI-6595175|ensembl:ENSP00000306138|uniprotkb:Q6J164 intact:EBI-6595175|ensembl:ENSP00000306138|uniprotkb:Q6J164 psi-mi:grm5_human(display_long)|uniprotkb:GRM5(gene name)|psi-mi:GRM5(display_short)|uniprotkb:GPRC1E(gene name synonym)|uniprotkb:MGLUR5(gene name synonym) psi-mi:grm5_human(display_long)|uniprotkb:GRM5(gene name)|psi-mi:GRM5(display_short)|uniprotkb:GPRC1E(gene name synonym)|uniprotkb:MGLUR5(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Koehl et al. (2019) pubmed:30675062|imex:IM-27213 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-21195701|wwpdb:6n4y|imex:IM-27213-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000168959(gene)|ensembl:ENST00000305447(transcript)|go:"GO:0001640"(adenylate cyclase inhibiting G protein-coupled glutamate receptor activity)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006417"(regulation of translation)|go:"GO:0006448"(regulation of translational elongation)|go:"GO:0007206"(phospholipase C-activating G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0030296"(protein tyrosine kinase activator activity)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050808"(synapse organization)|go:"GO:0050890"(cognition)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090647"(modulation of age-related behavioral decline)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:0099530"(G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential)|go:"GO:0099553"(trans-synaptic signaling by endocannabinoid, modulating synaptic transmission)|go:"GO:0099583"(neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:1902938"(regulation of intracellular calcium activated chloride channel activity)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000162(GPCR, family 3, metabotropic glutamate receptor)|interpro:IPR000202(GPCR, family 3, metabotropic glutamate receptor 5)|interpro:IPR000337(GPCR, family 3)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR011500(GPCR, family 3, nine cysteines region)|interpro:IPR017978|interpro:IPR017979|interpro:IPR019588|interpro:IPR028082|interpro:IPR038550|rcsb pdb:3LMK|rcsb pdb:4OO9|rcsb pdb:5CGC|rcsb pdb:5CGD|rcsb pdb:6N4X|rcsb pdb:6N4Y|rcsb pdb:6N50|rcsb pdb:6N51|rcsb pdb:6N52|reactome:R-HSA-416476|reactome:R-HSA-420499|reactome:R-HSA-6794361|refseq:XP_011541094.1|refseq:NP_000833.1|refseq:NP_001137303.1|refseq:XP_006718891.1|refseq:XP_016873116.1 ensembl:ENSG00000168959(gene)|ensembl:ENST00000305447(transcript)|go:"GO:0001640"(adenylate cyclase inhibiting G protein-coupled glutamate receptor activity)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006417"(regulation of translation)|go:"GO:0006448"(regulation of translational elongation)|go:"GO:0007206"(phospholipase C-activating G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0030296"(protein tyrosine kinase activator activity)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050808"(synapse organization)|go:"GO:0050890"(cognition)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090647"(modulation of age-related behavioral decline)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:0099530"(G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential)|go:"GO:0099553"(trans-synaptic signaling by endocannabinoid, modulating synaptic transmission)|go:"GO:0099583"(neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:1902938"(regulation of intracellular calcium activated chloride channel activity)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000162(GPCR, family 3, metabotropic glutamate receptor)|interpro:IPR000202(GPCR, family 3, metabotropic glutamate receptor 5)|interpro:IPR000337(GPCR, family 3)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR011500(GPCR, family 3, nine cysteines region)|interpro:IPR017978|interpro:IPR017979|interpro:IPR019588|interpro:IPR028082|interpro:IPR038550|rcsb pdb:3LMK|rcsb pdb:4OO9|rcsb pdb:5CGC|rcsb pdb:5CGD|rcsb pdb:6N4X|rcsb pdb:6N4Y|rcsb pdb:6N50|rcsb pdb:6N51|rcsb pdb:6N52|reactome:R-HSA-416476|reactome:R-HSA-420499|reactome:R-HSA-6794361|refseq:XP_011541094.1|refseq:NP_000833.1|refseq:NP_001137303.1|refseq:XP_006718891.1|refseq:XP_016873116.1 - - - figure legend:Fig 2. Ex Data Tab 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs) - 2019/02/07 2019/02/08 rogid:/kz6DJ8xJVDQPX6jEYoTGxmAMsw9606 rogid:/kz6DJ8xJVDQPX6jEYoTGxmAMsw9606 rigid:6rXInvtNd52SJlKpBCsHEAaUpFY false binding-associated region:21-569(6N50) binding-associated region:21-569(6N50) 2 0 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:P41594 uniprotkb:P41594 intact:EBI-6595175|ensembl:ENSP00000306138|uniprotkb:Q6J164 intact:EBI-6595175|ensembl:ENSP00000306138|uniprotkb:Q6J164 psi-mi:grm5_human(display_long)|uniprotkb:GRM5(gene name)|psi-mi:GRM5(display_short)|uniprotkb:GPRC1E(gene name synonym)|uniprotkb:MGLUR5(gene name synonym) psi-mi:grm5_human(display_long)|uniprotkb:GRM5(gene name)|psi-mi:GRM5(display_short)|uniprotkb:GPRC1E(gene name synonym)|uniprotkb:MGLUR5(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Koehl et al. (2019) pubmed:30675062|imex:IM-27213 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-21196547|wwpdb:6N4X|imex:IM-27213-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000168959(gene)|ensembl:ENST00000305447(transcript)|go:"GO:0001640"(adenylate cyclase inhibiting G protein-coupled glutamate receptor activity)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006417"(regulation of translation)|go:"GO:0006448"(regulation of translational elongation)|go:"GO:0007206"(phospholipase C-activating G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0030296"(protein tyrosine kinase activator activity)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050808"(synapse organization)|go:"GO:0050890"(cognition)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090647"(modulation of age-related behavioral decline)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:0099530"(G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential)|go:"GO:0099553"(trans-synaptic signaling by endocannabinoid, modulating synaptic transmission)|go:"GO:0099583"(neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:1902938"(regulation of intracellular calcium activated chloride channel activity)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000162(GPCR, family 3, metabotropic glutamate receptor)|interpro:IPR000202(GPCR, family 3, metabotropic glutamate receptor 5)|interpro:IPR000337(GPCR, family 3)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR011500(GPCR, family 3, nine cysteines region)|interpro:IPR017978|interpro:IPR017979|interpro:IPR019588|interpro:IPR028082|interpro:IPR038550|rcsb pdb:3LMK|rcsb pdb:4OO9|rcsb pdb:5CGC|rcsb pdb:5CGD|rcsb pdb:6N4X|rcsb pdb:6N4Y|rcsb pdb:6N50|rcsb pdb:6N51|rcsb pdb:6N52|reactome:R-HSA-416476|reactome:R-HSA-420499|reactome:R-HSA-6794361|refseq:XP_011541094.1|refseq:NP_000833.1|refseq:NP_001137303.1|refseq:XP_006718891.1|refseq:XP_016873116.1 ensembl:ENSG00000168959(gene)|ensembl:ENST00000305447(transcript)|go:"GO:0001640"(adenylate cyclase inhibiting G protein-coupled glutamate receptor activity)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006417"(regulation of translation)|go:"GO:0006448"(regulation of translational elongation)|go:"GO:0007206"(phospholipase C-activating G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0030296"(protein tyrosine kinase activator activity)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050808"(synapse organization)|go:"GO:0050890"(cognition)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090647"(modulation of age-related behavioral decline)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:0099530"(G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential)|go:"GO:0099553"(trans-synaptic signaling by endocannabinoid, modulating synaptic transmission)|go:"GO:0099583"(neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:1902938"(regulation of intracellular calcium activated chloride channel activity)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000162(GPCR, family 3, metabotropic glutamate receptor)|interpro:IPR000202(GPCR, family 3, metabotropic glutamate receptor 5)|interpro:IPR000337(GPCR, family 3)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR011500(GPCR, family 3, nine cysteines region)|interpro:IPR017978|interpro:IPR017979|interpro:IPR019588|interpro:IPR028082|interpro:IPR038550|rcsb pdb:3LMK|rcsb pdb:4OO9|rcsb pdb:5CGC|rcsb pdb:5CGD|rcsb pdb:6N4X|rcsb pdb:6N4Y|rcsb pdb:6N50|rcsb pdb:6N51|rcsb pdb:6N52|reactome:R-HSA-416476|reactome:R-HSA-420499|reactome:R-HSA-6794361|refseq:XP_011541094.1|refseq:NP_000833.1|refseq:NP_001137303.1|refseq:XP_006718891.1|refseq:XP_016873116.1 - - - figure legend:Fig 2. Ex Data Tab 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr)|taxid:7108("Spodoptera frugiperda (Fall armyworm)") - 2019/02/07 2019/02/08 rogid:/kz6DJ8xJVDQPX6jEYoTGxmAMsw9606 rogid:/kz6DJ8xJVDQPX6jEYoTGxmAMsw9606 rigid:6rXInvtNd52SJlKpBCsHEAaUpFY false ha tag:n-n|flag tag:n-n|binding-associated region:21-865 ha tag:n-n|flag tag:n-n|binding-associated region:21-865 2 0 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)