#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9UKJ1	uniprotkb:Q9NQX5	intact:EBI-965833|ensembl:ENSP00000198536|uniprotkb:Q8NHI1	intact:EBI-748927|uniprotkb:Q5SPY8|uniprotkb:Q9BTD6|uniprotkb:Q9BXT3|uniprotkb:Q9NQS2|uniprotkb:Q9Y434|ensembl:ENSP00000360660	psi-mi:pilra_human(display_long)|uniprotkb:PILRA(gene name)|psi-mi:PILRA(display_short)|uniprotkb:Inhibitory receptor PILR-alpha(gene name synonym)|uniprotkb:Cell surface receptor FDF03(gene name synonym)	psi-mi:npdc1_human(display_long)|uniprotkb:NPDC1(gene name)|psi-mi:NPDC1(display_short)	psi-mi:"MI:0054"(fluorescence-activated cell sorting)	Rathore et al. (2018)	pubmed:30388101|imex:IM-27382	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21198468|imex:IM-27382-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000085514(gene)|ensembl:ENST00000198536(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:3WUZ|rcsb pdb:3WV0|rcsb pdb:4NFB|rcsb pdb:5XO2|rcsb pdb:5XOF|reactome:R-HSA-198933|refseq:NP_038467.2|refseq:NP_840056.1|refseq:NP_840057.1	refseq:NP_056207.3|ensembl:ENSG00000107281(gene)|ensembl:ENST00000371601(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR009635(Neural proliferation differentiation control-1)|reactome:R-HSA-198933	-	-	-	figure legend:Fig. 1C, 3D, Supp Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/13	2019/02/13	rogid:QWSaRQHGXRXAOOMvijnTQztvSpY9606	rogid:XMT47N4ONSRPydRJyvdcqEyTs3Q9606	rigid:B9gXoMnqOmG+a/Ny+cH5nD9pkfY	false	mutation increasing interaction strength:80-80|mutation disrupting interaction strength:72-72|mutation disrupting interaction strength:76-76|mutation increasing interaction strength:78-78|mutation disrupting interaction strength:140-140|mutation increasing interaction strength:141-141	fc-igg tag:c-c|sufficient binding region:1-190	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:Q9UKJ1	uniprotkb:Q9NQX5	intact:EBI-965833|ensembl:ENSP00000198536|uniprotkb:Q8NHI1	intact:EBI-748927|uniprotkb:Q5SPY8|uniprotkb:Q9BTD6|uniprotkb:Q9BXT3|uniprotkb:Q9NQS2|uniprotkb:Q9Y434|ensembl:ENSP00000360660	psi-mi:pilra_human(display_long)|uniprotkb:PILRA(gene name)|psi-mi:PILRA(display_short)|uniprotkb:Inhibitory receptor PILR-alpha(gene name synonym)|uniprotkb:Cell surface receptor FDF03(gene name synonym)	psi-mi:npdc1_human(display_long)|uniprotkb:NPDC1(gene name)|psi-mi:NPDC1(display_short)	psi-mi:"MI:0054"(fluorescence-activated cell sorting)	Rathore et al. (2018)	pubmed:30388101|imex:IM-27382	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21198538|imex:IM-27382-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000085514(gene)|ensembl:ENST00000198536(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:3WUZ|rcsb pdb:3WV0|rcsb pdb:4NFB|rcsb pdb:5XO2|rcsb pdb:5XOF|reactome:R-HSA-198933|refseq:NP_038467.2|refseq:NP_840056.1|refseq:NP_840057.1	refseq:NP_056207.3|ensembl:ENSG00000107281(gene)|ensembl:ENST00000371601(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR009635(Neural proliferation differentiation control-1)|reactome:R-HSA-198933	-	-	-	figure legend:Fig. 1E, 2B Supp Fig. 4, 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/13	2019/02/13	rogid:QWSaRQHGXRXAOOMvijnTQztvSpY9606	rogid:XMT47N4ONSRPydRJyvdcqEyTs3Q9606	rigid:B9gXoMnqOmG+a/Ny+cH5nD9pkfY	false	fc-igg tag:c-c|sufficient binding region:1-196|mutation increasing interaction strength:80-80|mutation disrupting interaction strength:72-72|mutation disrupting interaction strength:76-76|mutation increasing interaction strength:78-78	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:Q9UKJ1	uniprotkb:A1Z0P7	intact:EBI-965833|ensembl:ENSP00000198536|uniprotkb:Q8NHI1	intact:EBI-21198571	psi-mi:pilra_human(display_long)|uniprotkb:PILRA(gene name)|psi-mi:PILRA(display_short)|uniprotkb:Inhibitory receptor PILR-alpha(gene name synonym)|uniprotkb:Cell surface receptor FDF03(gene name synonym)	psi-mi:a1z0p7_hhv1(display_long)|uniprotkb:UL27(gene name)|psi-mi:UL27(display_short)|uniprotkb:gB(gene name synonym)|uniprotkb:HHV1gp041(orf name)	psi-mi:"MI:0054"(fluorescence-activated cell sorting)	Rathore et al. (2018)	pubmed:30388101|imex:IM-27382	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10298(hhv1)|taxid:10298(Human herpesvirus 1)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21198589|imex:IM-27382-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000085514(gene)|ensembl:ENST00000198536(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:3WUZ|rcsb pdb:3WV0|rcsb pdb:4NFB|rcsb pdb:5XO2|rcsb pdb:5XOF|reactome:R-HSA-198933|refseq:NP_038467.2|refseq:NP_840056.1|refseq:NP_840057.1	go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0044175"(host cell endosome membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0055036"(virion membrane)|interpro:IPR035377|interpro:IPR035381|interpro:IPR038631|interpro:IPR000234(Herpesvirus Glycoprotein B)	-	-	-	figure legend:Fig. 1F, Supp. FIg. 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/13	2019/02/13	rogid:QWSaRQHGXRXAOOMvijnTQztvSpY9606	rogid:JL1F8IrZDDbVmg2n2aUbkjwQbSg10298	rigid:F5VG63DXEe46YebPTroIEZdva/A	false	fc-igg tag:c-c|sufficient binding region:1-196|mutation increasing interaction strength:80-80|mutation disrupting interaction strength:72-72|mutation disrupting interaction strength:76-76|mutation increasing interaction strength:78-78	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:Q9UKJ1	uniprotkb:Q8IYJ0	intact:EBI-965833|ensembl:ENSP00000198536|uniprotkb:Q8NHI1	intact:EBI-12204277|uniprotkb:A8K0T3|uniprotkb:B3KPF7|uniprotkb:B3KRI6|uniprotkb:Q6UX35|ensembl:ENSP00000317818|ensembl:ENSP00000442157	psi-mi:pilra_human(display_long)|uniprotkb:PILRA(gene name)|psi-mi:PILRA(display_short)|uniprotkb:Inhibitory receptor PILR-alpha(gene name synonym)|uniprotkb:Cell surface receptor FDF03(gene name synonym)	psi-mi:pianp_human(display_long)|uniprotkb:PIANP(gene name)|psi-mi:PIANP(display_short)|uniprotkb:C12orf53(gene name synonym)|uniprotkb:PANP(gene name synonym)|uniprotkb:PILR-associating neural protein(gene name synonym)|uniprotkb:Paired immunoglobin-like type 2 receptor-associating neural protein(gene name synonym)|uniprotkb:UNQ828/PRO1755(orf name)	psi-mi:"MI:0054"(fluorescence-activated cell sorting)	Rathore et al. (2018)	pubmed:30388101|imex:IM-27382	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21198608|imex:IM-27382-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000085514(gene)|ensembl:ENST00000198536(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:3WUZ|rcsb pdb:3WV0|rcsb pdb:4NFB|rcsb pdb:5XO2|rcsb pdb:5XOF|reactome:R-HSA-198933|refseq:NP_038467.2|refseq:NP_840056.1|refseq:NP_840057.1	refseq:NP_001230943.1|refseq:NP_001230944.1|refseq:NP_710152.1|ensembl:ENSG00000139200(gene)|ensembl:ENST00000320591(transcript)|ensembl:ENST00000540656(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0050776"(regulation of immune response)|interpro:IPR029198|interpro:IPR039628|reactome:R-HSA-198933	-	-	-	figure legend:Fig. 1G, Supp FIg. 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/13	2019/02/13	rogid:QWSaRQHGXRXAOOMvijnTQztvSpY9606	rogid:n4T+Br0iuayFhh5bmOssnkoM3789606	rigid:ARk416Ddbth1W0gepSGVVzgXWCE	false	fc-igg tag:c-c|sufficient binding region:1-196|mutation increasing interaction strength:80-80|mutation disrupting interaction strength:72-72|mutation disrupting interaction strength:76-76|mutation increasing interaction strength:78-78	myc tag:c-c	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:Q9UKJ1	uniprotkb:Q8WY21	intact:EBI-965833|ensembl:ENSP00000198536|uniprotkb:Q8NHI1	intact:EBI-21198627|ensembl:ENSP00000263054|uniprotkb:A2RRF4|uniprotkb:Q59GG7|uniprotkb:Q5JVT7|uniprotkb:Q5JVT8|uniprotkb:Q5VY14|uniprotkb:Q86WQ1|uniprotkb:Q86WQ2|uniprotkb:Q9H1Y1|uniprotkb:Q9H1Y2	psi-mi:pilra_human(display_long)|uniprotkb:PILRA(gene name)|psi-mi:PILRA(display_short)|uniprotkb:Inhibitory receptor PILR-alpha(gene name synonym)|uniprotkb:Cell surface receptor FDF03(gene name synonym)	psi-mi:sorc1_human(display_long)|uniprotkb:SORCS1(gene name)|psi-mi:SORCS1(display_short)|uniprotkb:SORCS(gene name synonym)	psi-mi:"MI:0054"(fluorescence-activated cell sorting)	Rathore et al. (2018)	pubmed:30388101|imex:IM-27382	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21198662|imex:IM-27382-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000085514(gene)|ensembl:ENST00000198536(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:3WUZ|rcsb pdb:3WV0|rcsb pdb:4NFB|rcsb pdb:5XO2|rcsb pdb:5XOF|reactome:R-HSA-198933|refseq:NP_038467.2|refseq:NP_840056.1|refseq:NP_840057.1	ensembl:ENSG00000108018(gene)|ensembl:ENST00000263054(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0008188"(neuropeptide receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000601(PKD)|interpro:IPR006581(VPS10)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031777|interpro:IPR031778|interpro:IPR035986|refseq:NP_001013049.1|refseq:NP_001193498.1|refseq:NP_001193499.1|refseq:NP_001193500.1|refseq:NP_001193501.1|refseq:NP_443150.3	-	-	-	figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/13	2019/02/13	rogid:QWSaRQHGXRXAOOMvijnTQztvSpY9606	rogid:bPunafWY9F5U9T5ikvKMSbBOkLE9606	rigid:3rS/dfam5My+7n8sIKAgjh2mrzk	false	fc-igg tag:c-c|sufficient binding region:1-196|mutation:78-78	tag:c-c|sufficient binding region:1-1102|fusion protein:c-c	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:Q9UKJ1	uniprotkb:P51693	intact:EBI-965833|ensembl:ENSP00000198536|uniprotkb:Q8NHI1	intact:EBI-74648|uniprotkb:O00113|uniprotkb:Q96A92|ensembl:ENSP00000498366	psi-mi:pilra_human(display_long)|uniprotkb:PILRA(gene name)|psi-mi:PILRA(display_short)|uniprotkb:Inhibitory receptor PILR-alpha(gene name synonym)|uniprotkb:Cell surface receptor FDF03(gene name synonym)	psi-mi:aplp1_human(display_long)|uniprotkb:APLP1(gene name)|psi-mi:APLP1(display_short)|uniprotkb:"Amyloid beta (A4) precursor-like protein 1"(gene name synonym)|uniprotkb:Amyloid-like protein 1(gene name synonym)	psi-mi:"MI:0054"(fluorescence-activated cell sorting)	Rathore et al. (2018)	pubmed:30388101|imex:IM-27382	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21198679|imex:IM-27382-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000085514(gene)|ensembl:ENST00000198536(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:3WUZ|rcsb pdb:3WV0|rcsb pdb:4NFB|rcsb pdb:5XO2|rcsb pdb:5XOF|reactome:R-HSA-198933|refseq:NP_038467.2|refseq:NP_840056.1|refseq:NP_840057.1	refseq:NP_001019978.1|refseq:NP_005157.1|dip:DIP-30846N|ensembl:ENSG00000105290(gene)|ensembl:ENST00000652533(transcript)|go:"GO:0005604"(basement membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0008201"(heparin binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030900"(forebrain development)|go:"GO:0031694"(alpha-2A adrenergic receptor binding)|go:"GO:0031695"(alpha-2B adrenergic receptor binding)|go:"GO:0031696"(alpha-2C adrenergic receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071874"(cellular response to norepinephrine stimulus)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|interpro:IPR008154(Amyloidogenic glycoprotein, extracellular)|interpro:IPR008155(Amyloidogenic glycoprotein, core)|interpro:IPR011178(Amyloidogenic glycoprotein, copper-binding)|interpro:IPR015849(Amyloidogenic glycoprotein, heparin-binding)|interpro:IPR019543|interpro:IPR019744|interpro:IPR019745|interpro:IPR024329|interpro:IPR036176|interpro:IPR036669|rcsb pdb:3PMR|rcsb pdb:3Q7G|rcsb pdb:3Q7L|rcsb pdb:3QMK|rcsb pdb:4RD9|rcsb pdb:4RDA|interpro:IPR036454	-	-	-	figure legend:Fig. 2B, Supp. Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/13	2019/02/13	rogid:QWSaRQHGXRXAOOMvijnTQztvSpY9606	rogid:6PKn8miZNOLOS3c4MjZFchs1yaQ9606	rigid:CzdGQ3WbX9hWsn5wucT95Vjvahw	false	fc-igg tag:c-c|sufficient binding region:1-196|mutation:78-78	sufficient binding region:1-580|tag:c-c|fusion protein:c-c	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:Q9UKJ1	uniprotkb:P0C0L4	intact:EBI-965833|ensembl:ENSP00000198536|uniprotkb:Q8NHI1	intact:EBI-1223619|uniprotkb:P01028|uniprotkb:P78445|uniprotkb:Q13160|uniprotkb:Q13906|uniprotkb:Q14033|uniprotkb:Q14835|uniprotkb:Q5JQM8|uniprotkb:Q9NPK5|uniprotkb:Q9UIP5|uniprotkb:B0QZR6|uniprotkb:A6H8M8|uniprotkb:A6NHJ5|uniprotkb:A7E2V2|uniprotkb:B0V2C8|uniprotkb:B2RUT6|uniprotkb:B7ZVZ6|uniprotkb:Q4LE82|uniprotkb:Q5JNX2|uniprotkb:Q6P4R1|uniprotkb:Q6U2E5|uniprotkb:Q6U2E8|uniprotkb:Q6U2F0|uniprotkb:Q6U2F3|uniprotkb:Q6U2F4|uniprotkb:Q6U2F6|uniprotkb:Q6U2F8|uniprotkb:Q6U2G0|uniprotkb:Q96EG2|uniprotkb:Q96SA8|ensembl:ENSP00000388662|ensembl:ENSP00000396688|ensembl:ENSP00000372815	psi-mi:pilra_human(display_long)|uniprotkb:PILRA(gene name)|psi-mi:PILRA(display_short)|uniprotkb:Inhibitory receptor PILR-alpha(gene name synonym)|uniprotkb:Cell surface receptor FDF03(gene name synonym)	psi-mi:co4a_human(display_long)|uniprotkb:C4A(gene name)|psi-mi:C4A(display_short)|uniprotkb:CO4(gene name synonym)|uniprotkb:CPAMD2(gene name synonym)|uniprotkb:Acidic complement C4(gene name synonym)|uniprotkb:C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2(gene name synonym)	psi-mi:"MI:0054"(fluorescence-activated cell sorting)	Rathore et al. (2018)	pubmed:30388101|imex:IM-27382	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21198689|imex:IM-27382-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000085514(gene)|ensembl:ENST00000198536(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:3WUZ|rcsb pdb:3WV0|rcsb pdb:4NFB|rcsb pdb:5XO2|rcsb pdb:5XOF|reactome:R-HSA-198933|refseq:NP_038467.2|refseq:NP_840056.1|refseq:NP_840057.1	refseq:NP_009224.2|refseq:NP_001002029.3|refseq:NP_001239133.1|ensembl:ENSG00000206340(gene)|ensembl:ENSG00000227746(gene)|ensembl:ENSG00000244731(gene)|ensembl:ENST00000383325(transcript)|ensembl:ENST00000421274(transcript)|ensembl:ENST00000428956(transcript)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0006956"(complement activation)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:2000427"(positive regulation of apoptotic cell clearance)|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR001840(Complement C3a/C4a/C5a anaphylatoxin)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018081|interpro:IPR018933|interpro:IPR019742|interpro:IPR036595|interpro:IPR037569|interpro:IPR040839|interpro:IPR041555|rcsb pdb:1HZF|rcsb pdb:4FXG|rcsb pdb:4FXK|rcsb pdb:4XAM|rcsb pdb:5JPM|rcsb pdb:5JPN|rcsb pdb:5JTW|reactome:R-HSA-166663|reactome:R-HSA-174577|reactome:R-HSA-381426|reactome:R-HSA-8957275|reactome:R-HSA-977606	-	-	-	figure legend:Fig. 2B, 2C, Supp. Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/13	2019/02/13	rogid:QWSaRQHGXRXAOOMvijnTQztvSpY9606	rogid:nLlIFlW5RCngnXASkYPGREjA/1E9606	rigid:q3QR0YNj6gdd0F6Z+zA8+chChQA	false	fc-igg tag:c-c|sufficient binding region:1-196|mutation increasing interaction strength:78-78|mutation disrupting interaction strength:76-76|mutation increasing interaction strength:80-80	tag:c-c|fusion protein:c-c	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:Q9UKJ1	uniprotkb:Q9NQX5	intact:EBI-965833|ensembl:ENSP00000198536|uniprotkb:Q8NHI1	intact:EBI-748927|uniprotkb:Q5SPY8|uniprotkb:Q9BTD6|uniprotkb:Q9BXT3|uniprotkb:Q9NQS2|uniprotkb:Q9Y434|ensembl:ENSP00000360660	psi-mi:pilra_human(display_long)|uniprotkb:PILRA(gene name)|psi-mi:PILRA(display_short)|uniprotkb:Inhibitory receptor PILR-alpha(gene name synonym)|uniprotkb:Cell surface receptor FDF03(gene name synonym)	psi-mi:npdc1_human(display_long)|uniprotkb:NPDC1(gene name)|psi-mi:NPDC1(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Rathore et al. (2018)	pubmed:30388101|imex:IM-27382	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21198714|imex:IM-27382-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000085514(gene)|ensembl:ENST00000198536(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:3WUZ|rcsb pdb:3WV0|rcsb pdb:4NFB|rcsb pdb:5XO2|rcsb pdb:5XOF|reactome:R-HSA-198933|refseq:NP_038467.2|refseq:NP_840056.1|refseq:NP_840057.1	refseq:NP_056207.3|ensembl:ENSG00000107281(gene)|ensembl:ENST00000371601(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR009635(Neural proliferation differentiation control-1)|reactome:R-HSA-198933	-	-	-	figure legend:Fig. 3E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/02/13	2019/02/13	rogid:QWSaRQHGXRXAOOMvijnTQztvSpY9606	rogid:XMT47N4ONSRPydRJyvdcqEyTs3Q9606	rigid:B9gXoMnqOmG+a/Ny+cH5nD9pkfY	false	fc-igg tag:c-c|S-myristoylated residue:1-196|mutation decreasing interaction strength:140-140|mutation increasing interaction strength:78-78	fc-igg tag:c-c|sufficient binding region:1-190	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)