#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q7L0Y3	uniprotkb:Q7L0Y3	intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356	intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356	psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym)	psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Oerum et al. (2018)	pubmed:29880640|imex:IM-27530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21298504|imex:IM-27530-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766	refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766	-	-	-	figure legend:Fig. 3A, Supp Figs. 3 & 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/05	2019/04/05	rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606	rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606	rigid:1XkryS9My8ofJIaL8PUYXOT6OxU	false	sufficient binding region:40-210|his tag:n-n|necessary binding region:20-194	sufficient binding region:40-210|his tag:n-n|necessary binding region:20-194	2	0	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q99714	uniprotkb:O15091	intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9	intact:EBI-2107070|ensembl:ENSP00000440915|uniprotkb:D3DS99|uniprotkb:D3DSA1|uniprotkb:B4DXD9|uniprotkb:B4E0S8|uniprotkb:B4E211|uniprotkb:Q86SZ4|uniprotkb:Q86YB5|uniprotkb:Q8N5L5|uniprotkb:C4AM93	psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)	psi-mi:mrpp3_human(display_long)|uniprotkb:PRORP(gene name)|psi-mi:PRORP(display_short)|uniprotkb:KIAA0391(gene name synonym)|uniprotkb:MRPP3(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 3(gene name synonym)|uniprotkb:Protein only RNase P catalytic subunit(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Oerum et al. (2018)	pubmed:29880640|imex:IM-27530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21299160|imex:IM-27530-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1	ensembl:ENSG00000100890(gene)|ensembl:ENST00000534898(transcript)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR031595|interpro:IPR033495|mint:O15091|refseq:XP_011535711.1|refseq:XP_011535712.1|refseq:NP_055487.2|refseq:NP_001243607.1|refseq:NP_001243608.1|refseq:NP_001243609.1|refseq:NP_001243610.1|refseq:XP_005268294.1|refseq:XP_016877324.1|refseq:XP_016877325.1|refseq:XP_016877326.1|rcsb pdb:4ROU|rcsb pdb:4XGL|rcsb pdb:4XGM|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766	-	-	-	figure legend:Fig. 5B, Supp. Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/05	2019/04/09	rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606	rogid:ecyf1CIBRAhf7Fgt7+UfnVcNHfs9606	-	false	-	his tag:n-n|sufficient binding region:51-583	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q99714	intact:EBI-21298681	intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9	ensembl:ENST00000387365	psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)	psi-mi:mt-ti_human_rna(display_short)|psi-mi:EBI-21298681(display_long)	psi-mi:"MI:0071"(molecular sieving)	Oerum et al. (2018)	pubmed:29880640|imex:IM-27530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21299160|imex:IM-27530-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0325"(transfer rna)	rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1	-	-	-	-	figure legend:Fig. 5B, Supp. Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/05	2019/04/09	rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606	-	-	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q99714	uniprotkb:Q7L0Y3	intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9	intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356	psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)	psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Oerum et al. (2018)	pubmed:29880640|imex:IM-27530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21299160|imex:IM-27530-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1	refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766	-	-	-	figure legend:Fig. 5B, Supp. Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/05	2019/04/09	rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606	rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606	-	false	-	sufficient binding region:40-403|his tag:n-n	-	2	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q99714	uniprotkb:O15091	intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9	intact:EBI-2107070|ensembl:ENSP00000440915|uniprotkb:D3DS99|uniprotkb:D3DSA1|uniprotkb:B4DXD9|uniprotkb:B4E0S8|uniprotkb:B4E211|uniprotkb:Q86SZ4|uniprotkb:Q86YB5|uniprotkb:Q8N5L5|uniprotkb:C4AM93	psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)	psi-mi:mrpp3_human(display_long)|uniprotkb:PRORP(gene name)|psi-mi:PRORP(display_short)|uniprotkb:KIAA0391(gene name synonym)|uniprotkb:MRPP3(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 3(gene name synonym)|uniprotkb:Protein only RNase P catalytic subunit(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Oerum et al. (2018)	pubmed:29880640|imex:IM-27530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21299174|imex:IM-27530-49	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1	ensembl:ENSG00000100890(gene)|ensembl:ENST00000534898(transcript)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR031595|interpro:IPR033495|mint:O15091|refseq:XP_011535711.1|refseq:XP_011535712.1|refseq:NP_055487.2|refseq:NP_001243607.1|refseq:NP_001243608.1|refseq:NP_001243609.1|refseq:NP_001243610.1|refseq:XP_005268294.1|refseq:XP_016877324.1|refseq:XP_016877325.1|refseq:XP_016877326.1|rcsb pdb:4ROU|rcsb pdb:4XGL|rcsb pdb:4XGM|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766	-	-	-	figure legend:Fig. 5B,Supp. Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/05	2019/04/09	rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606	rogid:ecyf1CIBRAhf7Fgt7+UfnVcNHfs9606	rigid:K0VQ4EGOInknB5ptFqkGVjMDVlE	false	-	his tag:n-n|sufficient binding region:51-583	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q99714	uniprotkb:Q7L0Y3	intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9	intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356	psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)	psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Oerum et al. (2018)	pubmed:29880640|imex:IM-27530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21299174|imex:IM-27530-49	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1	refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766	-	-	-	figure legend:Fig. 5B,Supp. Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/05	2019/04/09	rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606	rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606	rigid:K0VQ4EGOInknB5ptFqkGVjMDVlE	false	-	sufficient binding region:40-403|his tag:n-n	-	2	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q7L0Y3	uniprotkb:Q99714	intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356	intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9	psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym)	psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Oerum et al. (2018)	pubmed:29880640|imex:IM-27530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21299564|imex:IM-27530-51	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766	rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1	-	-	-	figure legend:Supp Fig. 3A, 3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/05	2019/04/09	rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606	rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606	rigid:wAVYN0xoUjcmdZPdfMOOg4yei1s	false	necessary binding region:195-403|sufficient binding region:40-403|his tag:n-n|necessary binding region:40-210	-	2	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q7L0Y3	uniprotkb:Q7L0Y3	intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356	intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356	psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym)	psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Oerum et al. (2018)	pubmed:29880640|imex:IM-27530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21298516|imex:IM-27530-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766	refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766	-	-	-	figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/05	2019/04/05	rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606	rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606	rigid:1XkryS9My8ofJIaL8PUYXOT6OxU	false	sufficient binding region:40-403|his tag:n-n	sufficient binding region:40-403|his tag:n-n	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q7L0Y3	uniprotkb:Q99714	intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356	intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9	psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym)	psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Oerum et al. (2018)	pubmed:29880640|imex:IM-27530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21298597|imex:IM-27530-41	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766	rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1	-	-	-	figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/05	2019/04/06	rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606	rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606	rigid:wAVYN0xoUjcmdZPdfMOOg4yei1s	false	necessary binding region:40-210|necessary binding region:195-403|sufficient binding region:40-403|his tag:n-n	-	2	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99714	intact:EBI-21298681	intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9	ensembl:ENST00000387365	psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)	psi-mi:mt-ti_human_rna(display_short)|psi-mi:EBI-21298681(display_long)	psi-mi:"MI:0071"(molecular sieving)	Oerum et al. (2018)	pubmed:29880640|imex:IM-27530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21298669|imex:IM-27530-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0325"(transfer rna)	rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1	-	-	-	-	figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/05	2019/04/08	rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606	-	-	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99714	uniprotkb:Q7L0Y3	intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9	intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356	psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)	psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Oerum et al. (2018)	pubmed:29880640|imex:IM-27530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21298669|imex:IM-27530-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1	refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766	-	-	-	figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/05	2019/04/08	rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606	rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606	-	false	-	sufficient binding region:40-403|his tag:n-n	-	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:67040"	uniprotkb:Q7L0Y3	intact:EBI-12520674	intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356	psi-mi:s-adenosyl-l-methioninate(display_short)|psi-mi:"CHEBI:67040"(display_long)|intact:AdoMet(synonym)|intact:S-Adenosylmethionine(synonym)|intact:SAM(synonym)|intact:"[(3S)-3-amino-3-carboxylatopropyl](5'-deoxyadenosin-5'-yl)(methyl)sulfonioacetate"(iupac name)	psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym)	psi-mi:"MI:1311"(differential scanning calorimetry)	Oerum et al. (2018)	pubmed:29880640|imex:IM-27530	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21298533|imex:IM-27530-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766	-	-	-	figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/05	2019/04/05	-	rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606	-	false	-	sufficient binding region:195-403(IPR028564)|his tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:136699"	uniprotkb:Q7L0Y3	intact:EBI-21298543	intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356	psi-mi:s-adenosyl-s-carboxymethyl-l-homocysteine(display_short)|psi-mi:"CHEBI:136699"(display_long)|intact:carboxy-SAM(synonym)|intact:Cx-SAM(synonym)|intact:carboxy-S-adenosyl-L-methionine(synonym)	psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym)	psi-mi:"MI:1311"(differential scanning calorimetry)	Oerum et al. (2018)	pubmed:29880640|imex:IM-27530	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21298548|imex:IM-27530-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766	-	-	-	figure legend:Supp. Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/05	2019/04/05	-	rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606	-	false	-	sufficient binding region:195-403(IPR028564)|his tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:28931"	uniprotkb:Q7L0Y3	intact:EBI-1778566	intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356	psi-mi:adenosine 3'-monophosphate(display_short)|psi-mi:"CHEBI:28931"(display_long)	psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym)	psi-mi:"MI:1311"(differential scanning calorimetry)	Oerum et al. (2018)	pubmed:29880640|imex:IM-27530	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21298556|interpro:IPR028564|imex:IM-27530-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766	-	-	-	figure legend:Supp. Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/05	2019/04/05	-	rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606	-	false	-	sufficient binding region:195-403|his tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q7L0Y3	uniprotkb:Q99714	intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356	intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9	psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym)	psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)	psi-mi:"MI:1311"(differential scanning calorimetry)	Oerum et al. (2018)	pubmed:29880640|imex:IM-27530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21299524|imex:IM-27530-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766	rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1	-	-	-	figure legend:Supp. Fig. 1F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/05	2019/04/09	rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606	rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606	rigid:wAVYN0xoUjcmdZPdfMOOg4yei1s	false	sufficient binding region:40-403|his tag:n-n	-	2	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:16908"	uniprotkb:Q99714	intact:EBI-4421847	intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9	psi-mi:nadh(display_short)|psi-mi:"CHEBI:16908"(display_long)	psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)	psi-mi:"MI:1311"(differential scanning calorimetry)	Oerum et al. (2018)	pubmed:29880640|imex:IM-27530	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21299536|imex:IM-27530-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1	-	-	-	figure legend:Supp. Fig. 1F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/05	2019/04/09	-	rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606	-	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99714	uniprotkb:Q7L0Y3	intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9	intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356	psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)	psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym)	psi-mi:"MI:1311"(differential scanning calorimetry)	Oerum et al. (2018)	pubmed:29880640|imex:IM-27530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21299536|imex:IM-27530-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1	refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766	-	-	-	figure legend:Supp. Fig. 1F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/05	2019/04/09	rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606	rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606	-	false	-	his tag:n-n|sufficient binding region:40-403	-	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:67040"	uniprotkb:Q99714	intact:EBI-12520674	intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9	psi-mi:s-adenosyl-l-methioninate(display_short)|psi-mi:"CHEBI:67040"(display_long)|intact:AdoMet(synonym)|intact:S-Adenosylmethionine(synonym)|intact:SAM(synonym)|intact:"[(3S)-3-amino-3-carboxylatopropyl](5'-deoxyadenosin-5'-yl)(methyl)sulfonioacetate"(iupac name)	psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)	psi-mi:"MI:1311"(differential scanning calorimetry)	Oerum et al. (2018)	pubmed:29880640|imex:IM-27530	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21299545|imex:IM-27530-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1	-	-	-	figure legend:Supp. Fig. 1F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/05	2019/04/09	-	rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606	-	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99714	uniprotkb:Q7L0Y3	intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9	intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356	psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)	psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym)	psi-mi:"MI:1311"(differential scanning calorimetry)	Oerum et al. (2018)	pubmed:29880640|imex:IM-27530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21299545|imex:IM-27530-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1	refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766	-	-	-	figure legend:Supp. Fig. 1F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/05	2019/04/09	rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606	rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606	-	false	-	his tag:n-n|sufficient binding region:40-403	-	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:67040"	uniprotkb:Q7L0Y3	intact:EBI-12520674	intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356	psi-mi:s-adenosyl-l-methioninate(display_short)|psi-mi:"CHEBI:67040"(display_long)|intact:AdoMet(synonym)|intact:S-Adenosylmethionine(synonym)|intact:SAM(synonym)|intact:"[(3S)-3-amino-3-carboxylatopropyl](5'-deoxyadenosin-5'-yl)(methyl)sulfonioacetate"(iupac name)	psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Oerum et al. (2018)	pubmed:29880640|imex:IM-27530	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21298572|wwpdb:5nfj|imex:IM-27530-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766	-	-	-	figure legend:Table 1|3d-r-factors:R work = 0.1946  R free = 0.2173|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/05	2019/04/05	-	rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606	-	false	-	sufficient binding region:203-403(IPR028564)|his tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q7L0Y3	uniprotkb:Q99714	intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356	intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9	psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym)	psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)	psi-mi:"MI:0081"(peptide array)	Oerum et al. (2018)	pubmed:29880640|imex:IM-27530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21298607|imex:IM-27530-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766	rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1	-	-	-	figure legend:Fig. 3C|comment:Additional binding regions were identified at end of the N domain and start of the methyltransferase domains, within the methyltransferase domain, and in the C terminal but exact coordinates were not given.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/05	2019/12/02	rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606	rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606	rigid:wAVYN0xoUjcmdZPdfMOOg4yei1s	false	sufficient binding region:40-403|sufficient binding region:100-105	his tag:n-n	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:Q7L0Y3	intact:EBI-21298681	intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356	ensembl:ENST00000387365	psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym)	psi-mi:mt-ti_human_rna(display_short)|psi-mi:EBI-21298681(display_long)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Oerum et al. (2018)	pubmed:29880640|imex:IM-27530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21298856|imex:IM-27530-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0325"(transfer rna)	refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766	-	-	-	-	figure legend:Fig.4C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/05	2019/12/02	rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606	-	-	false	sufficient binding region:40-210|his tag:n-n	-	2	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
intact:EBI-21298681	uniprotkb:Q7L0Y3	ensembl:ENST00000387365	intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356	psi-mi:mt-ti_human_rna(display_short)|psi-mi:EBI-21298681(display_long)	psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Oerum et al. (2018)	pubmed:29880640|imex:IM-27530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21298847|imex:IM-27530-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0325"(transfer rna)	psi-mi:"MI:0326"(protein)	-	refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766	-	-	-	figure legend:Fig. 4B, 4C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/05	2019/04/08	-	rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606	-	false	-	sufficient binding region:40-403|his tag:n-n	-	2	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
intact:EBI-21298681	uniprotkb:Q99714	ensembl:ENST00000387365	intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9	psi-mi:mt-ti_human_rna(display_short)|psi-mi:EBI-21298681(display_long)	psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Oerum et al. (2018)	pubmed:29880640|imex:IM-27530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21298847|imex:IM-27530-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0325"(transfer rna)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1	-	-	-	figure legend:Fig. 4B, 4C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/05	2019/04/08	-	rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606	-	false	-	-	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:Q99714	intact:EBI-21298681	intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9	ensembl:ENST00000387365	psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)	psi-mi:mt-ti_human_rna(display_short)|psi-mi:EBI-21298681(display_long)	psi-mi:"MI:0515"(methyltransferase assay)	Oerum et al. (2018)	pubmed:29880640|imex:IM-27530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0213"(methylation reaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21299053|imex:IM-27530-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0325"(transfer rna)	rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1	-	go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")	-	-	figure legend:Fig. 4D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/05	2019/12/02	rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606	-	-	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99714	uniprotkb:Q7L0Y3	intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9	intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356	psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)	psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym)	psi-mi:"MI:0515"(methyltransferase assay)	Oerum et al. (2018)	pubmed:29880640|imex:IM-27530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0213"(methylation reaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21299053|imex:IM-27530-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1	refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766	go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")	-	-	figure legend:Fig. 4D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/05	2019/12/02	rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606	rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606	-	false	-	his tag:n-n|mutation disrupting interaction rate:314-314|sufficient binding region:40-403|mutation disrupting interaction rate:226-226|necessary binding region:40-210|necessary binding region:203-380	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99714	intact:EBI-21299073	intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9	ensembl:ENST00000387342	psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)	psi-mi:mt-tv_human_rna(display_short)|psi-mi:EBI-21299073(display_long)	psi-mi:"MI:0515"(methyltransferase assay)	Oerum et al. (2018)	pubmed:29880640|imex:IM-27530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0213"(methylation reaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21299075|imex:IM-27530-43	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0325"(transfer rna)	rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1	-	go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")	-	-	figure legend:Fig. 4D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/05	2019/12/02	rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606	-	-	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99714	uniprotkb:Q7L0Y3	intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9	intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356	psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)	psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym)	psi-mi:"MI:0515"(methyltransferase assay)	Oerum et al. (2018)	pubmed:29880640|imex:IM-27530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0213"(methylation reaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21299075|imex:IM-27530-43	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1	refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766	go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")	-	-	figure legend:Fig. 4D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/05	2019/12/02	rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606	rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606	-	false	-	mutation disrupting interaction rate:314-314|sufficient binding region:40-403|his tag:n-n|mutation disrupting interaction rate:226-226|necessary binding region:40-210|necessary binding region:203-380	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:50169"	uniprotkb:Q99714	intact:EBI-21299102|chebi:"CHEBI:34347"|chebi:"CHEBI:32924"	intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9	psi-mi:brexanolone(display_short)|psi-mi:"CHEBI:50169"(display_long)|intact:"(3alpha,5alpha)-3-hydroxypregnan-20-one"(synonym)|intact:3alpha,5alpha-tetrahydroprogesterone(synonym)|intact:3alpha,5alpha-THP(synonym)|intact:3alpha-hydroxy-5alpha-dihydroprogesterone(synonym)|intact:3alpha-hydroxy-5alpha-pregnan-20-one(synonym)|intact:3alpha-OH DHP(synonym)|intact:5alpha-pregnan-3alpha-ol-20-one(synonym)|intact:allopregnan-3alpha-ol-20-one(synonym)|intact:allopregnanolone(synonym)|intact:allotetrahydroprogesterone(synonym)|intact:brexanolona(synonym)|intact:brexanolone(synonym)|intact:brexanolonum(synonym)|intact:SAGE-547(synonym)|intact:SGE-102(synonym)|intact:Zulresso(synonym)|intact:3alpha-hydroxy-5alpha-pregnan-20-one(iupac name)	psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)	psi-mi:"MI:0979"(oxidoreductase assay)	Oerum et al. (2018)	pubmed:29880640|imex:IM-27530	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0945"(oxidoreductase activity electron transfer reaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21299126|imex:IM-27530-45	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1	go:"GO:0035410"(dihydrotestosterone 17-beta-dehydrogenase activity)	-	-	figure legend:Fig. 4E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	km:7.7x10^-6(molar)	2019/04/05	2019/04/08	-	rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606	-	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99714	uniprotkb:O15091	intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9	intact:EBI-2107070|ensembl:ENSP00000440915|uniprotkb:D3DS99|uniprotkb:D3DSA1|uniprotkb:B4DXD9|uniprotkb:B4E0S8|uniprotkb:B4E211|uniprotkb:Q86SZ4|uniprotkb:Q86YB5|uniprotkb:Q8N5L5|uniprotkb:C4AM93	psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)	psi-mi:mrpp3_human(display_long)|uniprotkb:PRORP(gene name)|psi-mi:PRORP(display_short)|uniprotkb:KIAA0391(gene name synonym)|uniprotkb:MRPP3(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 3(gene name synonym)|uniprotkb:Protein only RNase P catalytic subunit(gene name synonym)	psi-mi:"MI:1034"(nuclease assay)	Oerum et al. (2018)	pubmed:29880640|imex:IM-27530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0902"(rna cleavage)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21299210|imex:IM-27530-35	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1	ensembl:ENSG00000100890(gene)|ensembl:ENST00000534898(transcript)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR031595|interpro:IPR033495|mint:O15091|refseq:XP_011535711.1|refseq:XP_011535712.1|refseq:NP_055487.2|refseq:NP_001243607.1|refseq:NP_001243608.1|refseq:NP_001243609.1|refseq:NP_001243610.1|refseq:XP_005268294.1|refseq:XP_016877324.1|refseq:XP_016877325.1|refseq:XP_016877326.1|rcsb pdb:4ROU|rcsb pdb:4XGL|rcsb pdb:4XGM|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766	go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")	-	-	figure legend:Fig. 5C, 5D|comment:Reaction is divalent metal cation dependent|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/05	2020/09/11	rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606	rogid:ecyf1CIBRAhf7Fgt7+UfnVcNHfs9606	-	false	-	necessary binding region:274-583,86-274|his tag:n-n|sufficient binding region:95-403	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99714	intact:EBI-21298681	intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9	ensembl:ENST00000387365	psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)	psi-mi:mt-ti_human_rna(display_short)|psi-mi:EBI-21298681(display_long)	psi-mi:"MI:1034"(nuclease assay)	Oerum et al. (2018)	pubmed:29880640|imex:IM-27530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0902"(rna cleavage)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21299210|imex:IM-27530-35	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0325"(transfer rna)	rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1	-	go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")	-	-	figure legend:Fig. 5C, 5D|comment:Reaction is divalent metal cation dependent|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/05	2020/09/11	rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606	-	-	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99714	uniprotkb:Q7L0Y3	intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9	intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356	psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)	psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym)	psi-mi:"MI:1034"(nuclease assay)	Oerum et al. (2018)	pubmed:29880640|imex:IM-27530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0902"(rna cleavage)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21299210|imex:IM-27530-35	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1	refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766	go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")	-	-	figure legend:Fig. 5C, 5D|comment:Reaction is divalent metal cation dependent|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/05	2020/09/11	rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606	rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606	-	false	-	his tag:n-n|sufficient binding region:40-403|necessary binding region:40-210|necessary binding region:203-380	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99714	uniprotkb:O15091	intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9	intact:EBI-2107070|ensembl:ENSP00000440915|uniprotkb:D3DS99|uniprotkb:D3DSA1|uniprotkb:B4DXD9|uniprotkb:B4E0S8|uniprotkb:B4E211|uniprotkb:Q86SZ4|uniprotkb:Q86YB5|uniprotkb:Q8N5L5|uniprotkb:C4AM93	psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)	psi-mi:mrpp3_human(display_long)|uniprotkb:PRORP(gene name)|psi-mi:PRORP(display_short)|uniprotkb:KIAA0391(gene name synonym)|uniprotkb:MRPP3(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 3(gene name synonym)|uniprotkb:Protein only RNase P catalytic subunit(gene name synonym)	psi-mi:"MI:0826"(x ray scattering)	Oerum et al. (2018)	pubmed:29880640|imex:IM-27530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21299485|imex:IM-27530-37	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1	ensembl:ENSG00000100890(gene)|ensembl:ENST00000534898(transcript)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR031595|interpro:IPR033495|mint:O15091|refseq:XP_011535711.1|refseq:XP_011535712.1|refseq:NP_055487.2|refseq:NP_001243607.1|refseq:NP_001243608.1|refseq:NP_001243609.1|refseq:NP_001243610.1|refseq:XP_005268294.1|refseq:XP_016877324.1|refseq:XP_016877325.1|refseq:XP_016877326.1|rcsb pdb:4ROU|rcsb pdb:4XGL|rcsb pdb:4XGM|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766	-	-	-	figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/05	2019/12/02	rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606	rogid:ecyf1CIBRAhf7Fgt7+UfnVcNHfs9606	-	false	-	his tag:n-n|sufficient binding region:51-583	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99714	intact:EBI-21298681	intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9	ensembl:ENST00000387365	psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)	psi-mi:mt-ti_human_rna(display_short)|psi-mi:EBI-21298681(display_long)	psi-mi:"MI:0826"(x ray scattering)	Oerum et al. (2018)	pubmed:29880640|imex:IM-27530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21299485|imex:IM-27530-37	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0325"(transfer rna)	rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1	-	-	-	-	figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/05	2019/12/02	rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606	-	-	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99714	uniprotkb:Q7L0Y3	intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9	intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356	psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)	psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym)	psi-mi:"MI:0826"(x ray scattering)	Oerum et al. (2018)	pubmed:29880640|imex:IM-27530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21299485|imex:IM-27530-37	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1	refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766	-	-	-	figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/05	2019/12/02	rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606	rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606	-	false	-	sufficient binding region:40-403|his tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99714	intact:EBI-21298681	intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9	ensembl:ENST00000387365	psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)	psi-mi:mt-ti_human_rna(display_short)|psi-mi:EBI-21298681(display_long)	psi-mi:"MI:0826"(x ray scattering)	Oerum et al. (2018)	pubmed:29880640|imex:IM-27530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21299499|imex:IM-27530-39	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0325"(transfer rna)	rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1	-	-	-	-	figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/05	2019/12/02	rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606	-	-	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99714	uniprotkb:Q7L0Y3	intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9	intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356	psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)	psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym)	psi-mi:"MI:0826"(x ray scattering)	Oerum et al. (2018)	pubmed:29880640|imex:IM-27530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21299499|imex:IM-27530-39	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1	refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766	-	-	-	figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/05	2019/12/02	rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606	rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606	-	false	-	sufficient binding region:40-403|his tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q7L0Y3	uniprotkb:Q99714	intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356	intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9	psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym)	psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)	psi-mi:"MI:0826"(x ray scattering)	Oerum et al. (2018)	pubmed:29880640|imex:IM-27530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22235441|imex:IM-27530-54	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766	rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1	-	-	-	figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/05	2019/12/02	rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606	rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606	rigid:wAVYN0xoUjcmdZPdfMOOg4yei1s	false	sufficient binding region:40-403|his tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q7L0Y3	uniprotkb:Q99714	intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356	intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9	psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym)	psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Oerum et al. (2018)	pubmed:29880640|imex:IM-27530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-21299595|imex:IM-27530-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766	rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1	-	-	-	figure legend:Supp Fig. 3C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2019/04/05	2019/12/02	rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606	rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606	rigid:wAVYN0xoUjcmdZPdfMOOg4yei1s	false	necessary binding region:195-403|sufficient binding region:40-403|his tag:n-n|necessary binding region:40-210	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q7L0Y3	uniprotkb:Q99714	intact:EBI-2107046|uniprotkb:Q9NRG5|uniprotkb:Q9NX54|uniprotkb:Q9Y596|ensembl:ENSP00000312356	intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9	psi-mi:tm10c_human(display_long)|uniprotkb:TRMT10C(gene name)|psi-mi:TRMT10C(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 2(gene name synonym)|uniprotkb:MRPP1(gene name synonym)|uniprotkb:RG9MTD1(gene name synonym)|uniprotkb:"RNA (guanine-9-)-methyltransferase domain-containing protein 1"(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-49(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 1(gene name synonym)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (adenine(9)-N(1))-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(9)-N(1))-methyltransferase"(gene name synonym)	psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Oerum et al. (2018)	pubmed:29880640|imex:IM-27530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22235348|imex:IM-27530-52	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060289.2|ensembl:ENSG00000174173(gene)|ensembl:ENST00000309922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009019"("tRNA (guanine-N1-)-methyltransferase activity")|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0052905"("tRNA (guanine(9)-N(1))-methyltransferase activity")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0090646"(mitochondrial tRNA processing)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR007356("tRNA (guanine-N1-)-methyltransferase, eukaryotic")|interpro:IPR016009("tRNA (guanine-N1-)-methyltransferase")|interpro:IPR025812|interpro:IPR028564|interpro:IPR038459|mint:Q7L0Y3|rcsb pdb:5NFJ|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766	rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1	-	-	-	figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/05	2019/12/02	rogid:ZvCWxNlWBon4eDq2zgzVTk3dI7U9606	rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606	rigid:wAVYN0xoUjcmdZPdfMOOg4yei1s	false	necessary binding region:40-210|necessary binding region:195-403|sufficient binding region:40-403|his tag:n-n	-	2	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)