#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q10570	uniprotkb:O95639-3	intact:EBI-347859|ensembl:ENSP00000478145|ensembl:ENSP00000484669|ensembl:ENSP00000495020|ensembl:ENSP00000495102|uniprotkb:Q96AF0	intact:EBI-21017617	psi-mi:cpsf1_human(display_long)|uniprotkb:CPSF1(gene name)|psi-mi:CPSF1(display_short)|uniprotkb:CPSF160(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 160 kDa subunit(gene name synonym)	psi-mi:o95639-3(display_long)|uniprotkb:Cleavage and polyadenylation specificity factor 30 kDa subunit(gene name synonym)|uniprotkb:NS1 effector domain-binding protein 1(gene name synonym)|uniprotkb:No arches homolog(gene name synonym)|uniprotkb:CPSF4(gene name)|psi-mi:CPSF4(display_short)|uniprotkb:CPSF30(gene name synonym)|uniprotkb:NAR(gene name synonym)|uniprotkb:NEB1(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Clerici et al. (2018)	imex:IM-27482|pubmed:29358758	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-22085845|imex:IM-27482-1|wwpdb:6FBS|emdb:EMD-4225	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6F9N|rcsb pdb:6FBS|rcsb pdb:6FUW|rcsb pdb:6URG|rcsb pdb:6URO|reactome:R-HSA-159231|reactome:R-HSA-6784531|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:6DNH|reactome:R-HSA-77595|ensembl:ENSG00000071894(gene)|ensembl:ENSG00000285049(gene)|ensembl:ENST00000616140(transcript)|ensembl:ENST00000620219(transcript)|ensembl:ENST00000643746(transcript)|ensembl:ENST00000644539(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|mint:Q10570|rcsb pdb:6BLY|rcsb pdb:6BM0|refseq:NP_037423.2|dip:DIP-32694N	intact:EBI-725860(isoform-parent)	-	-	isoform-comment:May be due to a competing acceptor splice site. No experimental confirmation available.	figure legend:fig. 1, Supplementary Table 1|caution:"This structure has four chains in total. One of the chains is a ten-nucleotide RNA; RNA (5'-R(P*AP*AP*UP*AP*AP*AP*GP*G)-3') (6FBS:D)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/10/11	2019/10/12	rogid:YZdY/qkUWUDbe+Dw3g9bY9DFbig9606	rogid:uUQLm5Edkx3iN4FHL80phvobem09606	rigid:SSlXcUj3gKH/mIci9IEdE/U8KiQ	false	binding-associated region:1-1443	binding-associated region:1-115	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:Q10570	uniprotkb:Q9C0J8-1	intact:EBI-347859|ensembl:ENSP00000478145|ensembl:ENSP00000484669|ensembl:ENSP00000495020|ensembl:ENSP00000495102|uniprotkb:Q96AF0	intact:EBI-21017610	psi-mi:cpsf1_human(display_long)|uniprotkb:CPSF1(gene name)|psi-mi:CPSF1(display_short)|uniprotkb:CPSF160(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 160 kDa subunit(gene name synonym)	psi-mi:q9c0j8-1(display_long)|uniprotkb:WDR33(gene name)|psi-mi:WDR33(display_short)|uniprotkb:WDC146(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Clerici et al. (2018)	imex:IM-27482|pubmed:29358758	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-22085845|imex:IM-27482-1|wwpdb:6FBS|emdb:EMD-4225	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6F9N|rcsb pdb:6FBS|rcsb pdb:6FUW|rcsb pdb:6URG|rcsb pdb:6URO|reactome:R-HSA-159231|reactome:R-HSA-6784531|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:6DNH|reactome:R-HSA-77595|ensembl:ENSG00000071894(gene)|ensembl:ENSG00000285049(gene)|ensembl:ENST00000616140(transcript)|ensembl:ENST00000620219(transcript)|ensembl:ENST00000643746(transcript)|ensembl:ENST00000644539(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|mint:Q10570|rcsb pdb:6BLY|rcsb pdb:6BM0|refseq:NP_037423.2|dip:DIP-32694N	uniprotkb:Q9C0J8-1(isoform-parent)	-	-	-	figure legend:fig. 1, Supplementary Table 1|caution:"This structure has four chains in total. One of the chains is a ten-nucleotide RNA; RNA (5'-R(P*AP*AP*UP*AP*AP*AP*GP*G)-3') (6FBS:D)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/10/11	2019/10/12	rogid:YZdY/qkUWUDbe+Dw3g9bY9DFbig9606	rogid:FzGeASJyKaYaqFQfFBYby692REg9606	rigid:SSlXcUj3gKH/mIci9IEdE/U8KiQ	false	binding-associated region:1-1443	binding-associated region:41-410	1	1	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:Q10570	uniprotkb:O95639-3	intact:EBI-347859|ensembl:ENSP00000478145|ensembl:ENSP00000484669|ensembl:ENSP00000495020|ensembl:ENSP00000495102|uniprotkb:Q96AF0	intact:EBI-21017617	psi-mi:cpsf1_human(display_long)|uniprotkb:CPSF1(gene name)|psi-mi:CPSF1(display_short)|uniprotkb:CPSF160(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 160 kDa subunit(gene name synonym)	psi-mi:o95639-3(display_long)|uniprotkb:Cleavage and polyadenylation specificity factor 30 kDa subunit(gene name synonym)|uniprotkb:NS1 effector domain-binding protein 1(gene name synonym)|uniprotkb:No arches homolog(gene name synonym)|uniprotkb:CPSF4(gene name)|psi-mi:CPSF4(display_short)|uniprotkb:CPSF30(gene name synonym)|uniprotkb:NAR(gene name synonym)|uniprotkb:NEB1(gene name synonym)	psi-mi:"MI:0808"(comigration in sds page)	Clerici et al. (2018)	imex:IM-27482|pubmed:29358758	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-22085870|imex:IM-27482-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6F9N|rcsb pdb:6FBS|rcsb pdb:6FUW|rcsb pdb:6URG|rcsb pdb:6URO|reactome:R-HSA-159231|reactome:R-HSA-6784531|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:6DNH|reactome:R-HSA-77595|ensembl:ENSG00000071894(gene)|ensembl:ENSG00000285049(gene)|ensembl:ENST00000616140(transcript)|ensembl:ENST00000620219(transcript)|ensembl:ENST00000643746(transcript)|ensembl:ENST00000644539(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|mint:Q10570|rcsb pdb:6BLY|rcsb pdb:6BM0|refseq:NP_037423.2|dip:DIP-32694N	intact:EBI-725860(isoform-parent)	-	-	isoform-comment:May be due to a competing acceptor splice site. No experimental confirmation available.	figure legend:Supplementary Figure 1a|caution:"This structure has four chains in total. One of the chains is a ten-nucleotide RNA; RNA (5'-R(P*AP*AP*UP*AP*AP*AP*GP*G)-3') (6FBS:D)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells)	-	2019/10/11	2019/11/13	rogid:YZdY/qkUWUDbe+Dw3g9bY9DFbig9606	rogid:uUQLm5Edkx3iN4FHL80phvobem09606	rigid:MajsRlLnM41ZYALjvmHLcnRgcM8	false	binding-associated region:1-1443	binding-associated region:1-115	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:Q10570	uniprotkb:Q6UN15-4	intact:EBI-347859|ensembl:ENSP00000478145|ensembl:ENSP00000484669|ensembl:ENSP00000495020|ensembl:ENSP00000495102|uniprotkb:Q96AF0	intact:EBI-21017602|ensembl:ENSP00000425456	psi-mi:cpsf1_human(display_long)|uniprotkb:CPSF1(gene name)|psi-mi:CPSF1(display_short)|uniprotkb:CPSF160(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 160 kDa subunit(gene name synonym)	psi-mi:q6un15-4(display_long)|uniprotkb:FIP1-like 1 protein(gene name synonym)|uniprotkb:Factor interacting with PAP(gene name synonym)|uniprotkb:Rearranged in hypereosinophilia(gene name synonym)|uniprotkb:FIP1L1(gene name)|psi-mi:FIP1L1(display_short)|uniprotkb:FIP1(gene name synonym)|uniprotkb:RHE(gene name synonym)	psi-mi:"MI:0808"(comigration in sds page)	Clerici et al. (2018)	imex:IM-27482|pubmed:29358758	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-22085870|imex:IM-27482-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6F9N|rcsb pdb:6FBS|rcsb pdb:6FUW|rcsb pdb:6URG|rcsb pdb:6URO|reactome:R-HSA-159231|reactome:R-HSA-6784531|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:6DNH|reactome:R-HSA-77595|ensembl:ENSG00000071894(gene)|ensembl:ENSG00000285049(gene)|ensembl:ENST00000616140(transcript)|ensembl:ENST00000620219(transcript)|ensembl:ENST00000643746(transcript)|ensembl:ENST00000644539(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|mint:Q10570|rcsb pdb:6BLY|rcsb pdb:6BM0|refseq:NP_037423.2|dip:DIP-32694N	intact:EBI-1021914(isoform-parent)|ensembl:ENSG00000145216(gene)|ensembl:ENST00000507922(transcript)	-	-	-	figure legend:Supplementary Figure 1a|caution:"This structure has four chains in total. One of the chains is a ten-nucleotide RNA; RNA (5'-R(P*AP*AP*UP*AP*AP*AP*GP*G)-3') (6FBS:D)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells)	-	2019/10/11	2019/11/13	rogid:YZdY/qkUWUDbe+Dw3g9bY9DFbig9606	rogid:NYN1C7eU8mO8RjY+8aeEXKHpc389606	rigid:MajsRlLnM41ZYALjvmHLcnRgcM8	false	binding-associated region:1-1443	binding-associated region:130-195	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:Q10570	uniprotkb:Q9C0J8-1	intact:EBI-347859|ensembl:ENSP00000478145|ensembl:ENSP00000484669|ensembl:ENSP00000495020|ensembl:ENSP00000495102|uniprotkb:Q96AF0	intact:EBI-21017610	psi-mi:cpsf1_human(display_long)|uniprotkb:CPSF1(gene name)|psi-mi:CPSF1(display_short)|uniprotkb:CPSF160(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 160 kDa subunit(gene name synonym)	psi-mi:q9c0j8-1(display_long)|uniprotkb:WDR33(gene name)|psi-mi:WDR33(display_short)|uniprotkb:WDC146(gene name synonym)	psi-mi:"MI:0808"(comigration in sds page)	Clerici et al. (2018)	imex:IM-27482|pubmed:29358758	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-22085870|imex:IM-27482-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6F9N|rcsb pdb:6FBS|rcsb pdb:6FUW|rcsb pdb:6URG|rcsb pdb:6URO|reactome:R-HSA-159231|reactome:R-HSA-6784531|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:6DNH|reactome:R-HSA-77595|ensembl:ENSG00000071894(gene)|ensembl:ENSG00000285049(gene)|ensembl:ENST00000616140(transcript)|ensembl:ENST00000620219(transcript)|ensembl:ENST00000643746(transcript)|ensembl:ENST00000644539(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|mint:Q10570|rcsb pdb:6BLY|rcsb pdb:6BM0|refseq:NP_037423.2|dip:DIP-32694N	uniprotkb:Q9C0J8-1(isoform-parent)	-	-	-	figure legend:Supplementary Figure 1a|caution:"This structure has four chains in total. One of the chains is a ten-nucleotide RNA; RNA (5'-R(P*AP*AP*UP*AP*AP*AP*GP*G)-3') (6FBS:D)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells)	-	2019/10/11	2019/11/13	rogid:YZdY/qkUWUDbe+Dw3g9bY9DFbig9606	rogid:FzGeASJyKaYaqFQfFBYby692REg9606	rigid:MajsRlLnM41ZYALjvmHLcnRgcM8	false	binding-associated region:1-1443	binding-associated region:41-410	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:2287"(identification by structure determination)