#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O00481 uniprotkb:P78410 intact:EBI-2809309|ensembl:ENSP00000289361|uniprotkb:Q147X5|uniprotkb:A2A278|uniprotkb:Q53F15|uniprotkb:Q99420|uniprotkb:Q0P515|uniprotkb:Q9HCY1|uniprotkb:A8K2C8|uniprotkb:B4DIQ1|uniprotkb:E9PHG8|uniprotkb:B4DRM2|uniprotkb:E9PGB4 intact:EBI-17564670|uniprotkb:B4DRT7|uniprotkb:B4E103|uniprotkb:F5H791|uniprotkb:F8W6E0|uniprotkb:O00477|uniprotkb:O15338|uniprotkb:O75658|uniprotkb:Q76PA0|uniprotkb:Q9BU81|uniprotkb:Q9NR44|ensembl:ENSP00000348751|ensembl:ENSP00000366937|ensembl:ENSP00000380152|ensembl:ENSP00000432138 psi-mi:bt3a1_human(display_long)|uniprotkb:BTN3A1(gene name)|psi-mi:BTN3A1(display_short)|uniprotkb:BTF5(gene name synonym) psi-mi:bt3a2_human(display_long)|uniprotkb:BTN3A2(gene name)|psi-mi:BTN3A2(display_short)|uniprotkb:BT3.2(gene name synonym)|uniprotkb:BTF3(gene name synonym)|uniprotkb:BTF4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Vantourout et al. (2018) pubmed:29339503|imex:IM-27242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-21979851|imex:IM-27242-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000026950(gene)|ensembl:ENST00000289361(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0050798"(activated T cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037954|interpro:IPR043136|rcsb pdb:4F80|rcsb pdb:4F9L|rcsb pdb:4F9P|rcsb pdb:4JKW|rcsb pdb:4K55|rcsb pdb:4N7I|rcsb pdb:4N7U|rcsb pdb:4V1P|rcsb pdb:5HM7|rcsb pdb:5LYG|rcsb pdb:5LYK|rcsb pdb:5ZXK|rcsb pdb:6ISM|rcsb pdb:6ITA|rcsb pdb:6J06|rcsb pdb:6XLQ|reactome:R-HSA-8851680|refseq:NP_001138480.1|refseq:NP_001138481.1|refseq:NP_008979.3|refseq:NP_919423.1|refseq:XP_005248891.1 refseq:NP_001184175.1|refseq:NP_001184176.1|refseq:NP_001184177.1|refseq:NP_001184178.1|refseq:NP_008978.2|refseq:XP_005248884.1|refseq:XP_016865700.1|refseq:XP_016865701.1|refseq:XP_016865703.1|ensembl:ENSG00000186470(gene)|ensembl:ENST00000356386(transcript)|ensembl:ENST00000377708(transcript)|ensembl:ENST00000396948(transcript)|ensembl:ENST00000527422(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0002456"(T cell mediated immunity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:4F8Q|reactome:R-HSA-8851680 - - - figure legend:Fig. 2A, Supp. Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/08/07 2019/08/07 rogid:Qx4k0aSGUrS7rLeSZzv3QJLmM6o9606 rogid:I9g4kIWVNaUQ5xIRw0dFe0CsA6w9606 rigid:FNTm2ftxZQtY+RlppuZQM4DBjHk false flag tag:n-n ha tag:n-n|necessary binding region:153..153-234..234 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O00481 uniprotkb:O00478 intact:EBI-2809309|ensembl:ENSP00000289361|uniprotkb:Q147X5|uniprotkb:A2A278|uniprotkb:Q53F15|uniprotkb:Q99420|uniprotkb:Q0P515|uniprotkb:Q9HCY1|uniprotkb:A8K2C8|uniprotkb:B4DIQ1|uniprotkb:E9PHG8|uniprotkb:B4DRM2|uniprotkb:E9PGB4 intact:EBI-2837387|uniprotkb:B4DWI7|uniprotkb:E9PCP5|ensembl:ENSP00000244519 psi-mi:bt3a1_human(display_long)|uniprotkb:BTN3A1(gene name)|psi-mi:BTN3A1(display_short)|uniprotkb:BTF5(gene name synonym) psi-mi:bt3a3_human(display_long)|uniprotkb:BTN3A3(gene name)|psi-mi:BTN3A3(display_short)|uniprotkb:BTF3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Vantourout et al. (2018) pubmed:29339503|imex:IM-27242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-21979997|imex:IM-27242-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000026950(gene)|ensembl:ENST00000289361(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0050798"(activated T cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037954|interpro:IPR043136|rcsb pdb:4F80|rcsb pdb:4F9L|rcsb pdb:4F9P|rcsb pdb:4JKW|rcsb pdb:4K55|rcsb pdb:4N7I|rcsb pdb:4N7U|rcsb pdb:4V1P|rcsb pdb:5HM7|rcsb pdb:5LYG|rcsb pdb:5LYK|rcsb pdb:5ZXK|rcsb pdb:6ISM|rcsb pdb:6ITA|rcsb pdb:6J06|rcsb pdb:6XLQ|reactome:R-HSA-8851680|refseq:NP_001138480.1|refseq:NP_001138481.1|refseq:NP_008979.3|refseq:NP_919423.1|refseq:XP_005248891.1 refseq:NP_001229732.1|refseq:NP_008925.1|refseq:NP_932078.2|interpro:IPR043136|rcsb pdb:4F8T|rcsb pdb:5ZZ3|rcsb pdb:6J0G|rcsb pdb:6J0K|rcsb pdb:6J0L|reactome:R-HSA-8851680|interpro:IPR037954|ensembl:ENSG00000111801(gene)|ensembl:ENST00000244519(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0002456"(T cell mediated immunity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179 - - - figure legend:Supp. Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/08/07 2019/08/07 rogid:Qx4k0aSGUrS7rLeSZzv3QJLmM6o9606 rogid:fQdqpHl1dd0xV76P8O6gBaa+py09606 rigid:zuxiLCMRwlS4rzOaldH/9Fk2G08 false flag tag:n-n ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q6UXE8 uniprotkb:Q6UX41 intact:EBI-21583619|ensembl:ENSP00000341787|uniprotkb:Q496L7|uniprotkb:Q9Y2C7 intact:EBI-4314379|uniprotkb:Q9H730|uniprotkb:A4QMZ8|uniprotkb:B7Z409|uniprotkb:E9PEF6|uniprotkb:E9PG07|uniprotkb:A6NEX6|uniprotkb:B7Z5B1|uniprotkb:F2Z2B2|uniprotkb:F8W712|intact:EBI-28985330|ensembl:ENSP00000342197 psi-mi:btnl3_human(display_long)|uniprotkb:Butyrophilin-like receptor(gene name synonym)|uniprotkb:BTNL3(gene name)|psi-mi:BTNL3(display_short)|uniprotkb:BTNLR(gene name synonym)|uniprotkb:COLF4100(gene name synonym)|uniprotkb:UNQ744/PRO1472(orf name) psi-mi:btnl8_human(display_long)|uniprotkb:BTNL8(gene name)|psi-mi:BTNL8(display_short)|uniprotkb:UNQ702/PRO1347(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Vantourout et al. (2018) pubmed:29339503|imex:IM-27242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-21980016|imex:IM-27242-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000168903(gene)|ensembl:ENST00000342868(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR043136|refseq:NP_932079.1 refseq:NP_001035552.1|refseq:NP_001153179.1|refseq:NP_001153180.1|refseq:NP_001153181.1|refseq:NP_001153182.1|refseq:NP_079126.1|ensembl:ENST00000231229|ensembl:ENSP00000231229|ensembl:ENSP00000342197|ensembl:ENST00000400707|ensembl:ENSP00000383543|ensembl:ENST00000508408|ensembl:ENSP00000424585|ensembl:ENST00000511704|ensembl:ENSP00000425207|ensembl:ENST00000533815|ensembl:ENSP00000435098|ensembl:ENST00000610640|ensembl:ENSP00000483717|ensembl:ENSG00000113303(gene)|ensembl:ENST00000340184(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR043136|reactome:R-HSA-8851680 - - - figure legend:Supp. Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/08/07 2019/08/07 rogid:TKoWo//6A/V6GODOJCAEQw34F8Y9606 rogid:Eo+M4bJU2EN6LjZqQ5pPWdiMEvo9606 rigid:8ts+gBSqGrNff0diz5JFcnZfBJw false flag tag:n-n ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O00481 uniprotkb:P78410 intact:EBI-2809309|ensembl:ENSP00000289361|uniprotkb:Q147X5|uniprotkb:A2A278|uniprotkb:Q53F15|uniprotkb:Q99420|uniprotkb:Q0P515|uniprotkb:Q9HCY1|uniprotkb:A8K2C8|uniprotkb:B4DIQ1|uniprotkb:E9PHG8|uniprotkb:B4DRM2|uniprotkb:E9PGB4 intact:EBI-17564670|uniprotkb:B4DRT7|uniprotkb:B4E103|uniprotkb:F5H791|uniprotkb:F8W6E0|uniprotkb:O00477|uniprotkb:O15338|uniprotkb:O75658|uniprotkb:Q76PA0|uniprotkb:Q9BU81|uniprotkb:Q9NR44|ensembl:ENSP00000348751|ensembl:ENSP00000366937|ensembl:ENSP00000380152|ensembl:ENSP00000432138 psi-mi:bt3a1_human(display_long)|uniprotkb:BTN3A1(gene name)|psi-mi:BTN3A1(display_short)|uniprotkb:BTF5(gene name synonym) psi-mi:bt3a2_human(display_long)|uniprotkb:BTN3A2(gene name)|psi-mi:BTN3A2(display_short)|uniprotkb:BT3.2(gene name synonym)|uniprotkb:BTF3(gene name synonym)|uniprotkb:BTF4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Vantourout et al. (2018) pubmed:29339503|imex:IM-27242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-21979910|imex:IM-27242-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000026950(gene)|ensembl:ENST00000289361(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0050798"(activated T cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037954|interpro:IPR043136|rcsb pdb:4F80|rcsb pdb:4F9L|rcsb pdb:4F9P|rcsb pdb:4JKW|rcsb pdb:4K55|rcsb pdb:4N7I|rcsb pdb:4N7U|rcsb pdb:4V1P|rcsb pdb:5HM7|rcsb pdb:5LYG|rcsb pdb:5LYK|rcsb pdb:5ZXK|rcsb pdb:6ISM|rcsb pdb:6ITA|rcsb pdb:6J06|rcsb pdb:6XLQ|reactome:R-HSA-8851680|refseq:NP_001138480.1|refseq:NP_001138481.1|refseq:NP_008979.3|refseq:NP_919423.1|refseq:XP_005248891.1 refseq:NP_001184175.1|refseq:NP_001184176.1|refseq:NP_001184177.1|refseq:NP_001184178.1|refseq:NP_008978.2|refseq:XP_005248884.1|refseq:XP_016865700.1|refseq:XP_016865701.1|refseq:XP_016865703.1|ensembl:ENSG00000186470(gene)|ensembl:ENST00000356386(transcript)|ensembl:ENST00000377708(transcript)|ensembl:ENST00000396948(transcript)|ensembl:ENST00000527422(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0002456"(T cell mediated immunity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:4F8Q|reactome:R-HSA-8851680 - - - figure legend:Fig. 2B, Supp. Fig. 3C|comment:"Plotting protein intensity ratios (Welch Difference) versus log10 sum of intensities, BTN3A1 wasthe most greatly enriched high-intensity species in anti-FLAG immunoprecipitates from cells cotransduced with FLAG-3A1+HA-3A2 versus cells transduced with empty vector"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/08/07 2019/08/07 rogid:Qx4k0aSGUrS7rLeSZzv3QJLmM6o9606 rogid:I9g4kIWVNaUQ5xIRw0dFe0CsA6w9606 rigid:FNTm2ftxZQtY+RlppuZQM4DBjHk false flag tag:n-n ha tag:n-n|necessary binding region:153..153-234..234 - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q6UXE8 uniprotkb:Q6UX41 intact:EBI-21583619|ensembl:ENSP00000341787|uniprotkb:Q496L7|uniprotkb:Q9Y2C7 intact:EBI-4314379|uniprotkb:Q9H730|uniprotkb:A4QMZ8|uniprotkb:B7Z409|uniprotkb:E9PEF6|uniprotkb:E9PG07|uniprotkb:A6NEX6|uniprotkb:B7Z5B1|uniprotkb:F2Z2B2|uniprotkb:F8W712|intact:EBI-28985330|ensembl:ENSP00000342197 psi-mi:btnl3_human(display_long)|uniprotkb:Butyrophilin-like receptor(gene name synonym)|uniprotkb:BTNL3(gene name)|psi-mi:BTNL3(display_short)|uniprotkb:BTNLR(gene name synonym)|uniprotkb:COLF4100(gene name synonym)|uniprotkb:UNQ744/PRO1472(orf name) psi-mi:btnl8_human(display_long)|uniprotkb:BTNL8(gene name)|psi-mi:BTNL8(display_short)|uniprotkb:UNQ702/PRO1347(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Vantourout et al. (2018) pubmed:29339503|imex:IM-27242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-21980032|imex:IM-27242-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000168903(gene)|ensembl:ENST00000342868(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR043136|refseq:NP_932079.1 refseq:NP_001035552.1|refseq:NP_001153179.1|refseq:NP_001153180.1|refseq:NP_001153181.1|refseq:NP_001153182.1|refseq:NP_079126.1|ensembl:ENST00000231229|ensembl:ENSP00000231229|ensembl:ENSP00000342197|ensembl:ENST00000400707|ensembl:ENSP00000383543|ensembl:ENST00000508408|ensembl:ENSP00000424585|ensembl:ENST00000511704|ensembl:ENSP00000425207|ensembl:ENST00000533815|ensembl:ENSP00000435098|ensembl:ENST00000610640|ensembl:ENSP00000483717|ensembl:ENSG00000113303(gene)|ensembl:ENST00000340184(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR043136|reactome:R-HSA-8851680 - - - figure legend:Fig. 2B, Supp. Fig. 3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/08/07 2019/08/07 rogid:TKoWo//6A/V6GODOJCAEQw34F8Y9606 rogid:Eo+M4bJU2EN6LjZqQ5pPWdiMEvo9606 rigid:8ts+gBSqGrNff0diz5JFcnZfBJw false flag tag:n-n ha tag:n-n - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00481 uniprotkb:P78410 intact:EBI-2809309|ensembl:ENSP00000289361|uniprotkb:Q147X5|uniprotkb:A2A278|uniprotkb:Q53F15|uniprotkb:Q99420|uniprotkb:Q0P515|uniprotkb:Q9HCY1|uniprotkb:A8K2C8|uniprotkb:B4DIQ1|uniprotkb:E9PHG8|uniprotkb:B4DRM2|uniprotkb:E9PGB4 intact:EBI-17564670|uniprotkb:B4DRT7|uniprotkb:B4E103|uniprotkb:F5H791|uniprotkb:F8W6E0|uniprotkb:O00477|uniprotkb:O15338|uniprotkb:O75658|uniprotkb:Q76PA0|uniprotkb:Q9BU81|uniprotkb:Q9NR44|ensembl:ENSP00000348751|ensembl:ENSP00000366937|ensembl:ENSP00000380152|ensembl:ENSP00000432138 psi-mi:bt3a1_human(display_long)|uniprotkb:BTN3A1(gene name)|psi-mi:BTN3A1(display_short)|uniprotkb:BTF5(gene name synonym) psi-mi:bt3a2_human(display_long)|uniprotkb:BTN3A2(gene name)|psi-mi:BTN3A2(display_short)|uniprotkb:BT3.2(gene name synonym)|uniprotkb:BTF3(gene name synonym)|uniprotkb:BTF4(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Vantourout et al. (2018) pubmed:29339503|imex:IM-27242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-21980080|imex:IM-27242-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000026950(gene)|ensembl:ENST00000289361(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0050798"(activated T cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037954|interpro:IPR043136|rcsb pdb:4F80|rcsb pdb:4F9L|rcsb pdb:4F9P|rcsb pdb:4JKW|rcsb pdb:4K55|rcsb pdb:4N7I|rcsb pdb:4N7U|rcsb pdb:4V1P|rcsb pdb:5HM7|rcsb pdb:5LYG|rcsb pdb:5LYK|rcsb pdb:5ZXK|rcsb pdb:6ISM|rcsb pdb:6ITA|rcsb pdb:6J06|rcsb pdb:6XLQ|reactome:R-HSA-8851680|refseq:NP_001138480.1|refseq:NP_001138481.1|refseq:NP_008979.3|refseq:NP_919423.1|refseq:XP_005248891.1 refseq:NP_001184175.1|refseq:NP_001184176.1|refseq:NP_001184177.1|refseq:NP_001184178.1|refseq:NP_008978.2|refseq:XP_005248884.1|refseq:XP_016865700.1|refseq:XP_016865701.1|refseq:XP_016865703.1|ensembl:ENSG00000186470(gene)|ensembl:ENST00000356386(transcript)|ensembl:ENST00000377708(transcript)|ensembl:ENST00000396948(transcript)|ensembl:ENST00000527422(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0002456"(T cell mediated immunity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:4F8Q|reactome:R-HSA-8851680 - - - figure legend:Supp. Fig. 5B|comment:Cells required permeabilization for colocalization to be observed.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/08/07 2019/08/07 rogid:Qx4k0aSGUrS7rLeSZzv3QJLmM6o9606 rogid:I9g4kIWVNaUQ5xIRw0dFe0CsA6w9606 rigid:FNTm2ftxZQtY+RlppuZQM4DBjHk false flag tag:n-n ha tag:n-n|necessary binding region:153..153-234..234 - - psi-mi:"MI:1201"(anti-tag immunocytochemistry) psi-mi:"MI:1201"(anti-tag immunocytochemistry)