#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q8NA31	uniprotkb:P54274	intact:EBI-21942840|uniprotkb:A0AUW1|ensembl:ENSP00000462883|ensembl:ENSP00000463762	intact:EBI-710997|uniprotkb:A7XP29|uniprotkb:Q15553|uniprotkb:Q93029|ensembl:ENSP00000276603|uniprotkb:Q8NHT6	psi-mi:terb1_human(display_long)|uniprotkb:Coiled-coil domain-containing protein 79(gene name synonym)|uniprotkb:TERB1(gene name)|psi-mi:TERB1(display_short)|uniprotkb:CCDC79(gene name synonym)	psi-mi:terf1_human(display_long)|uniprotkb:TTAGGG repeat-binding factor 1(gene name synonym)|uniprotkb:NIMA-interacting protein 2(gene name synonym)|uniprotkb:Telomeric protein Pin2/TRF1(gene name synonym)|uniprotkb:TERF1(gene name)|psi-mi:TERF1(display_short)|uniprotkb:PIN2(gene name synonym)|uniprotkb:TRF(gene name synonym)|uniprotkb:TRF1(gene name synonym)|uniprotkb:TRBF1(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Long et al. (2017)	pubmed:29083416|imex:IM-27349	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-21942838|wwpdb:5XUP|imex:IM-27349-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001129977.1|refseq:XP_011521306.1|refseq:XP_011521307.1|refseq:XP_011521308.1|refseq:XP_011521309.1|refseq:XP_011521310.1|refseq:XP_011521311.1|refseq:XP_011521320.1|ensembl:ENSG00000249961(gene)|ensembl:ENST00000433154(transcript)|ensembl:ENST00000558713(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0070187"(shelterin complex)|go:"GO:0070197"(meiotic attachment of telomere to nuclear envelope)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017930|interpro:IPR042359|rcsb pdb:5WIR|rcsb pdb:5XUP|rcsb pdb:6J07	refseq:NP_003209.2|refseq:NP_059523.2|ensembl:ENSG00000147601(gene)|go:"GO:0051301"(cell division)|go:"GO:0051974"(negative regulation of telomerase activity)|ensembl:ENST00000276603(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0016604"(nuclear body)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032214"(negative regulation of telomere maintenance via semi-conservative replication)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045141"(meiotic telomere clustering)|interpro:IPR013867(Telomere repeat binding factor, dimerisation)|interpro:IPR017357(Telomeric repeat-binding factor 1, Pin2)|interpro:IPR017930|interpro:IPR036507|mint:P54274|rcsb pdb:1BA5|rcsb pdb:1H6O|rcsb pdb:1ITY|rcsb pdb:1IV6|rcsb pdb:1W0T|rcsb pdb:3BQO|rcsb pdb:3L82|rcsb pdb:5HKP|rcsb pdb:5WIR|rcsb pdb:5XUP|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0070187"(shelterin complex)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0090656"(t-circle formation)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904792"(positive regulation of shelterin complex assembly)|go:"GO:1904850"(negative regulation of establishment of protein localization to telomere)|go:"GO:1904911"(negative regulation of establishment of RNA localization to telomere)|go:"GO:1904914"(negative regulation of establishment of protein-containing complex localization to telomere)|go:"GO:1905778"(negative regulation of exonuclease activity)|go:"GO:1905839"(negative regulation of telomeric D-loop disassembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|dip:DIP-29412N	-	-	-	figure legend:Fig 1d, Table 1, Supplementary Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/07/30	2019/11/25	rogid:Zq68ImbOLa86/B99z5coVUY1eZA9606	rogid:3Tjmp8hqEhLBIQqxxWHntpL4hz49606	rigid:733TkE9/NlqNZuYsNlP3bPWG08k	false	binding-associated region:642-656	binding-associated region:65-267	2	2	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P54274	uniprotkb:Q8NA31	intact:EBI-710997|uniprotkb:A7XP29|uniprotkb:Q15553|uniprotkb:Q93029|ensembl:ENSP00000276603|uniprotkb:Q8NHT6	intact:EBI-21942840|uniprotkb:A0AUW1|ensembl:ENSP00000462883|ensembl:ENSP00000463762	psi-mi:terf1_human(display_long)|uniprotkb:TTAGGG repeat-binding factor 1(gene name synonym)|uniprotkb:NIMA-interacting protein 2(gene name synonym)|uniprotkb:Telomeric protein Pin2/TRF1(gene name synonym)|uniprotkb:TERF1(gene name)|psi-mi:TERF1(display_short)|uniprotkb:PIN2(gene name synonym)|uniprotkb:TRF(gene name synonym)|uniprotkb:TRF1(gene name synonym)|uniprotkb:TRBF1(gene name synonym)	psi-mi:terb1_human(display_long)|uniprotkb:Coiled-coil domain-containing protein 79(gene name synonym)|uniprotkb:TERB1(gene name)|psi-mi:TERB1(display_short)|uniprotkb:CCDC79(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Long et al. (2017)	pubmed:29083416|imex:IM-27349	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-21942892|imex:IM-27349-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003209.2|refseq:NP_059523.2|ensembl:ENSG00000147601(gene)|go:"GO:0051301"(cell division)|go:"GO:0051974"(negative regulation of telomerase activity)|ensembl:ENST00000276603(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0016604"(nuclear body)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032214"(negative regulation of telomere maintenance via semi-conservative replication)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045141"(meiotic telomere clustering)|interpro:IPR013867(Telomere repeat binding factor, dimerisation)|interpro:IPR017357(Telomeric repeat-binding factor 1, Pin2)|interpro:IPR017930|interpro:IPR036507|mint:P54274|rcsb pdb:1BA5|rcsb pdb:1H6O|rcsb pdb:1ITY|rcsb pdb:1IV6|rcsb pdb:1W0T|rcsb pdb:3BQO|rcsb pdb:3L82|rcsb pdb:5HKP|rcsb pdb:5WIR|rcsb pdb:5XUP|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0070187"(shelterin complex)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0090656"(t-circle formation)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904792"(positive regulation of shelterin complex assembly)|go:"GO:1904850"(negative regulation of establishment of protein localization to telomere)|go:"GO:1904911"(negative regulation of establishment of RNA localization to telomere)|go:"GO:1904914"(negative regulation of establishment of protein-containing complex localization to telomere)|go:"GO:1905778"(negative regulation of exonuclease activity)|go:"GO:1905839"(negative regulation of telomeric D-loop disassembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|dip:DIP-29412N	refseq:NP_001129977.1|refseq:XP_011521306.1|refseq:XP_011521307.1|refseq:XP_011521308.1|refseq:XP_011521309.1|refseq:XP_011521310.1|refseq:XP_011521311.1|refseq:XP_011521320.1|ensembl:ENSG00000249961(gene)|ensembl:ENST00000433154(transcript)|ensembl:ENST00000558713(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0070187"(shelterin complex)|go:"GO:0070197"(meiotic attachment of telomere to nuclear envelope)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017930|interpro:IPR042359|rcsb pdb:5WIR|rcsb pdb:5XUP|rcsb pdb:6J07	-	-	-	figure legend:Fig 2a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/07/30	2019/07/30	rogid:3Tjmp8hqEhLBIQqxxWHntpL4hz49606	rogid:Zq68ImbOLa86/B99z5coVUY1eZA9606	rigid:733TkE9/NlqNZuYsNlP3bPWG08k	false	myc tag:?-?|binding-associated region:65-267	flag tag:?-?|mutation disrupting interaction rate:647-647|binding-associated region:642-656|mutation disrupting interaction rate:648-648|mutation disrupting interaction rate:649-649	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P54274	uniprotkb:Q8NA31	intact:EBI-710997|uniprotkb:A7XP29|uniprotkb:Q15553|uniprotkb:Q93029|ensembl:ENSP00000276603|uniprotkb:Q8NHT6	intact:EBI-21942840|uniprotkb:A0AUW1|ensembl:ENSP00000462883|ensembl:ENSP00000463762	psi-mi:terf1_human(display_long)|uniprotkb:TTAGGG repeat-binding factor 1(gene name synonym)|uniprotkb:NIMA-interacting protein 2(gene name synonym)|uniprotkb:Telomeric protein Pin2/TRF1(gene name synonym)|uniprotkb:TERF1(gene name)|psi-mi:TERF1(display_short)|uniprotkb:PIN2(gene name synonym)|uniprotkb:TRF(gene name synonym)|uniprotkb:TRF1(gene name synonym)|uniprotkb:TRBF1(gene name synonym)	psi-mi:terb1_human(display_long)|uniprotkb:Coiled-coil domain-containing protein 79(gene name synonym)|uniprotkb:TERB1(gene name)|psi-mi:TERB1(display_short)|uniprotkb:CCDC79(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Long et al. (2017)	pubmed:29083416|imex:IM-27349	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-22230328|imex:IM-27349-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003209.2|refseq:NP_059523.2|ensembl:ENSG00000147601(gene)|go:"GO:0051301"(cell division)|go:"GO:0051974"(negative regulation of telomerase activity)|ensembl:ENST00000276603(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0016604"(nuclear body)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032214"(negative regulation of telomere maintenance via semi-conservative replication)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045141"(meiotic telomere clustering)|interpro:IPR013867(Telomere repeat binding factor, dimerisation)|interpro:IPR017357(Telomeric repeat-binding factor 1, Pin2)|interpro:IPR017930|interpro:IPR036507|mint:P54274|rcsb pdb:1BA5|rcsb pdb:1H6O|rcsb pdb:1ITY|rcsb pdb:1IV6|rcsb pdb:1W0T|rcsb pdb:3BQO|rcsb pdb:3L82|rcsb pdb:5HKP|rcsb pdb:5WIR|rcsb pdb:5XUP|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0070187"(shelterin complex)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0090656"(t-circle formation)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904792"(positive regulation of shelterin complex assembly)|go:"GO:1904850"(negative regulation of establishment of protein localization to telomere)|go:"GO:1904911"(negative regulation of establishment of RNA localization to telomere)|go:"GO:1904914"(negative regulation of establishment of protein-containing complex localization to telomere)|go:"GO:1905778"(negative regulation of exonuclease activity)|go:"GO:1905839"(negative regulation of telomeric D-loop disassembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|dip:DIP-29412N	refseq:NP_001129977.1|refseq:XP_011521306.1|refseq:XP_011521307.1|refseq:XP_011521308.1|refseq:XP_011521309.1|refseq:XP_011521310.1|refseq:XP_011521311.1|refseq:XP_011521320.1|ensembl:ENSG00000249961(gene)|ensembl:ENST00000433154(transcript)|ensembl:ENST00000558713(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0070187"(shelterin complex)|go:"GO:0070197"(meiotic attachment of telomere to nuclear envelope)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017930|interpro:IPR042359|rcsb pdb:5WIR|rcsb pdb:5XUP|rcsb pdb:6J07	-	-	-	figure legend:Fig 1b, Supplementary Fig 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/07/30	2019/11/27	rogid:3Tjmp8hqEhLBIQqxxWHntpL4hz49606	rogid:Zq68ImbOLa86/B99z5coVUY1eZA9606	rigid:733TkE9/NlqNZuYsNlP3bPWG08k	false	myc tag:?-?|binding-associated region:65-267	flag tag:?-?|mutation disrupting interaction rate:647-647|binding-associated region:642-656|mutation disrupting interaction rate:648-648|mutation disrupting interaction rate:649-649	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8NA31	uniprotkb:P54274	intact:EBI-21942840|uniprotkb:A0AUW1|ensembl:ENSP00000462883|ensembl:ENSP00000463762	intact:EBI-710997|uniprotkb:A7XP29|uniprotkb:Q15553|uniprotkb:Q93029|ensembl:ENSP00000276603|uniprotkb:Q8NHT6	psi-mi:terb1_human(display_long)|uniprotkb:Coiled-coil domain-containing protein 79(gene name synonym)|uniprotkb:TERB1(gene name)|psi-mi:TERB1(display_short)|uniprotkb:CCDC79(gene name synonym)	psi-mi:terf1_human(display_long)|uniprotkb:TTAGGG repeat-binding factor 1(gene name synonym)|uniprotkb:NIMA-interacting protein 2(gene name synonym)|uniprotkb:Telomeric protein Pin2/TRF1(gene name synonym)|uniprotkb:TERF1(gene name)|psi-mi:TERF1(display_short)|uniprotkb:PIN2(gene name synonym)|uniprotkb:TRF(gene name synonym)|uniprotkb:TRF1(gene name synonym)|uniprotkb:TRBF1(gene name synonym)	psi-mi:"MI:0051"(fluorescence technology)	Long et al. (2017)	pubmed:29083416|imex:IM-27349	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0465"(DIP)	intact:EBI-22230310|imex:IM-27349-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001129977.1|refseq:XP_011521306.1|refseq:XP_011521307.1|refseq:XP_011521308.1|refseq:XP_011521309.1|refseq:XP_011521310.1|refseq:XP_011521311.1|refseq:XP_011521320.1|ensembl:ENSG00000249961(gene)|ensembl:ENST00000433154(transcript)|ensembl:ENST00000558713(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0070187"(shelterin complex)|go:"GO:0070197"(meiotic attachment of telomere to nuclear envelope)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017930|interpro:IPR042359|rcsb pdb:5WIR|rcsb pdb:5XUP|rcsb pdb:6J07	refseq:NP_003209.2|refseq:NP_059523.2|ensembl:ENSG00000147601(gene)|go:"GO:0051301"(cell division)|go:"GO:0051974"(negative regulation of telomerase activity)|ensembl:ENST00000276603(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0016604"(nuclear body)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032214"(negative regulation of telomere maintenance via semi-conservative replication)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045141"(meiotic telomere clustering)|interpro:IPR013867(Telomere repeat binding factor, dimerisation)|interpro:IPR017357(Telomeric repeat-binding factor 1, Pin2)|interpro:IPR017930|interpro:IPR036507|mint:P54274|rcsb pdb:1BA5|rcsb pdb:1H6O|rcsb pdb:1ITY|rcsb pdb:1IV6|rcsb pdb:1W0T|rcsb pdb:3BQO|rcsb pdb:3L82|rcsb pdb:5HKP|rcsb pdb:5WIR|rcsb pdb:5XUP|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0070187"(shelterin complex)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0090656"(t-circle formation)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904792"(positive regulation of shelterin complex assembly)|go:"GO:1904850"(negative regulation of establishment of protein localization to telomere)|go:"GO:1904911"(negative regulation of establishment of RNA localization to telomere)|go:"GO:1904914"(negative regulation of establishment of protein-containing complex localization to telomere)|go:"GO:1905778"(negative regulation of exonuclease activity)|go:"GO:1905839"(negative regulation of telomeric D-loop disassembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|dip:DIP-29412N	go:"GO:0000781"(chromosome, telomeric region)	-	-	figure legend:Fig 2b, Supplementary Fig 8a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/07/30	2019/11/27	rogid:Zq68ImbOLa86/B99z5coVUY1eZA9606	rogid:3Tjmp8hqEhLBIQqxxWHntpL4hz49606	rigid:733TkE9/NlqNZuYsNlP3bPWG08k	false	mutation:647-647|mutation:648-648|mutation:649-649	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)