#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9P805 uniprotkb:O13828 intact:EBI-7557105|intact:MINT-4706793|ensemblfungi:"SPBC3B9.21.1:pep" intact:EBI-3647323|ensemblfungi:"SPAC19A8.12.1:pep" psi-mi:dcp1_schpo(display_long)|uniprotkb:dcp1(gene name)|psi-mi:dcp1(display_short)|uniprotkb:SPBC3B9.21(orf name) psi-mi:dcp2_schpo(display_long)|uniprotkb:dcp2(gene name)|psi-mi:dcp2(display_short)|uniprotkb:SPAC19A8.12(orf name) psi-mi:"MI:0114"(x-ray crystallography) Mugridge et al. (2016) imex:IM-27394|pubmed:27694842 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-21945261|wwpdb:5KQ1|wwpdb:5KQ4|imex:IM-27394-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_596662.1|ensemblfungi:SPBC3B9.21(gene)|ensemblfungi:SPBC3B9.21.1(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0034428"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 5'-3')|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0098745"(Dcp1-Dcp2 complex)|go:"GO:1990521"("m7G(5')pppN diphosphatase activator activity")|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|rcsb pdb:2QKL|rcsb pdb:2QKM|rcsb pdb:5J3Q|rcsb pdb:5J3T|rcsb pdb:5J3Y|rcsb pdb:5JP4|rcsb pdb:5KQ1|rcsb pdb:5KQ4|rcsb pdb:5N2V|dip:DIP-29008N ensemblfungi:SPAC19A8.12(gene)|ensemblfungi:SPAC19A8.12.1(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006397"(mRNA processing)|dip:DIP-29009N|refseq:NP_593780.1|go:"GO:0030145"(manganese ion binding)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0034428"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 5'-3')|go:"GO:0050072"("m7G(5')pppN diphosphatase activity")|go:"GO:0098745"(Dcp1-Dcp2 complex)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR007722(Dcp2, box A)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR036189|interpro:IPR044099|rcsb pdb:2A6T|rcsb pdb:2QKL|rcsb pdb:2QKM|rcsb pdb:4A54|rcsb pdb:5J3T|rcsb pdb:5J3Y|rcsb pdb:5KQ1|rcsb pdb:5KQ4|rcsb pdb:5N2V|go:"GO:0010494"(cytoplasmic stress granule) - crc64:DD593F646C61EEC0|comment:mint crc64:B405257B706BC5C0 figure legend:Fig 1a, Table 1, Supplementary Fig 2a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/08/02 2019/08/02 rogid:YZahMq6jxl25BLHhbj42A2988no284812 rogid:uPlzZ3jzyTUxQS0apuaQDOEhpiE284812 rigid:8K04dnfm6vBfIimVuxjtJf8YlAY false - binding-associated region:1-243 1 1 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:Q9P805 uniprotkb:Q9NPJ4 intact:EBI-7557105|intact:MINT-4706793|ensemblfungi:"SPBC3B9.21.1:pep" intact:EBI-726549|uniprotkb:B4DU72|ensembl:ENSP00000334840|ensembl:ENSP00000363592|ensembl:ENSP00000497590 psi-mi:dcp1_schpo(display_long)|uniprotkb:dcp1(gene name)|psi-mi:dcp1(display_short)|uniprotkb:SPBC3B9.21(orf name) psi-mi:pnrc2_human(display_long)|uniprotkb:PNRC2(gene name)|psi-mi:PNRC2(display_short)|uniprotkb:HSPC208(orf name) psi-mi:"MI:0114"(x-ray crystallography) Mugridge et al. (2016) imex:IM-27394|pubmed:27694842 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-21945261|wwpdb:5KQ1|wwpdb:5KQ4|imex:IM-27394-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_596662.1|ensemblfungi:SPBC3B9.21(gene)|ensemblfungi:SPBC3B9.21.1(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0034428"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 5'-3')|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0098745"(Dcp1-Dcp2 complex)|go:"GO:1990521"("m7G(5')pppN diphosphatase activator activity")|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|rcsb pdb:2QKL|rcsb pdb:2QKM|rcsb pdb:5J3Q|rcsb pdb:5J3T|rcsb pdb:5J3Y|rcsb pdb:5JP4|rcsb pdb:5KQ1|rcsb pdb:5KQ4|rcsb pdb:5N2V|dip:DIP-29008N refseq:NP_060231.1|refseq:XP_016857180.1|ensembl:ENSG00000189266(gene)|ensembl:ENST00000334351(transcript)|ensembl:ENST00000374468(transcript)|ensembl:ENST00000647887(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|interpro:IPR026780|interpro:IPR026781|rcsb pdb:4B6H|rcsb pdb:5KQ1|rcsb pdb:5KQ4|reactome:R-HSA-975957|dip:DIP-41328N - crc64:DD593F646C61EEC0|comment:mint - figure legend:Fig 1a, Table 1, Supplementary Fig 2a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/08/02 2019/08/02 rogid:YZahMq6jxl25BLHhbj42A2988no284812 rogid:95yy4wkOEjSuRUGby7OanMTNtCk9606 rigid:8K04dnfm6vBfIimVuxjtJf8YlAY false - binding-associated region:91-121 1 1 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)