#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P51149	uniprotkb:Q9Y4G2	intact:EBI-1056089|uniprotkb:A8K3V6|uniprotkb:Q9NWJ0|uniprotkb:Q9UPB0|ensembl:ENSP00000265062|ensembl:ENSP00000501618|ensembl:ENSP00000502000|ensembl:ENSP00000502088|ensembl:ENSP00000502486	intact:EBI-473814|uniprotkb:Q6P2R5|uniprotkb:Q8TEL9|uniprotkb:Q9NPP5|intact:EBI-715406|uniprotkb:Q9NYA0|ensembl:ENSP00000389913|ensembl:ENSP00000479066|ensembl:ENSP00000483820	psi-mi:rab7a_human(display_long)|uniprotkb:RAB7A(gene name)|psi-mi:RAB7A(display_short)|uniprotkb:RAB7(gene name synonym)	psi-mi:pkhm1_human(display_long)|uniprotkb:PLEKHM1(gene name)|psi-mi:PLEKHM1(display_short)|uniprotkb:KIAA0356(gene name synonym)|uniprotkb:162 kDa adapter protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bo et al. (2016)	pubmed:27291868|imex:IM-27217	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21950027|imex:IM-27217-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004628.4|ensembl:ENSG00000075785(gene)|ensembl:ENST00000265062(transcript)|ensembl:ENST00000674589(transcript)|ensembl:ENST00000675342(transcript)|ensembl:ENST00000675497(transcript)|ensembl:ENST00000676214(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006897"(endocytosis)|go:"GO:0007174"(epidermal growth factor catabolic process)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0019003"(GDP binding)|go:"GO:0019076"(viral release from host cell)|go:"GO:0022615"(protein to membrane docking)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032419"(extrinsic component of lysosome membrane)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0061724"(lipophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090382"(phagosome maturation)|go:"GO:0090383"(phagosome acidification)|go:"GO:0090385"(phagosome-lysosome fusion)|go:"GO:0099638"(endosome to plasma membrane protein transport)|go:"GO:1902586"(obsolete multi-organism intercellular transport)|go:"GO:1903542"(negative regulation of exosomal secretion)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1905366"(negative regulation of intralumenal vesicle formation)|go:"GO:1905394"(retromer complex binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P51149|rcsb pdb:1T91|rcsb pdb:1YHN|rcsb pdb:6IYB|rcsb pdb:6WCW|reactome:R-HSA-2132295|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9636383|reactome:R-HSA-9636569|rcsb pdb:3LAW|dip:DIP-39879N	refseq:NP_055613.1|refseq:XP_011523825.1|refseq:XP_011523826.1|refseq:XP_006722264.1|ensembl:ENSG00000225190(gene)|ensembl:ENSG00000276358(gene)|ensembl:ENSG00000277111(gene)|ensembl:ENST00000430334(transcript)|ensembl:ENST00000613787(transcript)|ensembl:ENST00000617688(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0015031"(protein transport)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044754"(autolysosome)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0046872"(metal ion binding)|go:"GO:0061909"(autophagosome-lysosome fusion)|go:"GO:1900029"(positive regulation of ruffle assembly)|go:"GO:1902774"(late endosome to lysosome transport)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR004012(RUN)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR025258|interpro:IPR037213|interpro:IPR042827|rcsb pdb:5DPR|rcsb pdb:5DPS|rcsb pdb:5DPT|rcsb pdb:5DPW|refseq:XP_016880940.1|refseq:XP_016880942.1	-	-	-	figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2019/08/05	2019/08/05	rogid:AJbKizzw4zCAn+roRF2Im1Tt4xE9606	rogid:g3g9CyLRMoFDvX6Yoc231I8+y5E9606	rigid:DX3RnPfZBwW5FevVhxlUVDEeRqE	false	green fluorescent protein tag:?-?	flag tag:?-?|mutation decreasing interaction strength:1018-1056	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P51149	uniprotkb:Q9Y4G2	intact:EBI-1056089|uniprotkb:A8K3V6|uniprotkb:Q9NWJ0|uniprotkb:Q9UPB0|ensembl:ENSP00000265062|ensembl:ENSP00000501618|ensembl:ENSP00000502000|ensembl:ENSP00000502088|ensembl:ENSP00000502486	intact:EBI-473814|uniprotkb:Q6P2R5|uniprotkb:Q8TEL9|uniprotkb:Q9NPP5|intact:EBI-715406|uniprotkb:Q9NYA0|ensembl:ENSP00000389913|ensembl:ENSP00000479066|ensembl:ENSP00000483820	psi-mi:rab7a_human(display_long)|uniprotkb:RAB7A(gene name)|psi-mi:RAB7A(display_short)|uniprotkb:RAB7(gene name synonym)	psi-mi:pkhm1_human(display_long)|uniprotkb:PLEKHM1(gene name)|psi-mi:PLEKHM1(display_short)|uniprotkb:KIAA0356(gene name synonym)|uniprotkb:162 kDa adapter protein(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Bo et al. (2016)	pubmed:27291868|imex:IM-27217	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21950048|imex:IM-27217-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004628.4|ensembl:ENSG00000075785(gene)|ensembl:ENST00000265062(transcript)|ensembl:ENST00000674589(transcript)|ensembl:ENST00000675342(transcript)|ensembl:ENST00000675497(transcript)|ensembl:ENST00000676214(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006897"(endocytosis)|go:"GO:0007174"(epidermal growth factor catabolic process)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0019003"(GDP binding)|go:"GO:0019076"(viral release from host cell)|go:"GO:0022615"(protein to membrane docking)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032419"(extrinsic component of lysosome membrane)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0061724"(lipophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090382"(phagosome maturation)|go:"GO:0090383"(phagosome acidification)|go:"GO:0090385"(phagosome-lysosome fusion)|go:"GO:0099638"(endosome to plasma membrane protein transport)|go:"GO:1902586"(obsolete multi-organism intercellular transport)|go:"GO:1903542"(negative regulation of exosomal secretion)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1905366"(negative regulation of intralumenal vesicle formation)|go:"GO:1905394"(retromer complex binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P51149|rcsb pdb:1T91|rcsb pdb:1YHN|rcsb pdb:6IYB|rcsb pdb:6WCW|reactome:R-HSA-2132295|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9636383|reactome:R-HSA-9636569|rcsb pdb:3LAW|dip:DIP-39879N	refseq:NP_055613.1|refseq:XP_011523825.1|refseq:XP_011523826.1|refseq:XP_006722264.1|ensembl:ENSG00000225190(gene)|ensembl:ENSG00000276358(gene)|ensembl:ENSG00000277111(gene)|ensembl:ENST00000430334(transcript)|ensembl:ENST00000613787(transcript)|ensembl:ENST00000617688(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0015031"(protein transport)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044754"(autolysosome)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0046872"(metal ion binding)|go:"GO:0061909"(autophagosome-lysosome fusion)|go:"GO:1900029"(positive regulation of ruffle assembly)|go:"GO:1902774"(late endosome to lysosome transport)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR004012(RUN)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR025258|interpro:IPR037213|interpro:IPR042827|rcsb pdb:5DPR|rcsb pdb:5DPS|rcsb pdb:5DPT|rcsb pdb:5DPW|refseq:XP_016880940.1|refseq:XP_016880942.1	go:"GO:0005737"(cytoplasm)	-	-	figure legend:Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2019/08/05	2019/09/16	rogid:AJbKizzw4zCAn+roRF2Im1Tt4xE9606	rogid:g3g9CyLRMoFDvX6Yoc231I8+y5E9606	rigid:DX3RnPfZBwW5FevVhxlUVDEeRqE	false	green fluorescent protein tag:?-?	flag tag:?-?|mutation decreasing interaction strength:1018-1056	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)