#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q16799-3	uniprotkb:P55145	intact:EBI-10180131|ensembl:ENSP00000340716	intact:EBI-1044104|uniprotkb:Q14CX4|uniprotkb:Q86U67|uniprotkb:Q96IS4|ensembl:ENSP00000432799	psi-mi:q16799-3(display_long)|uniprotkb:NSP(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)|uniprotkb:NSP-C(isoform synonym)|uniprotkb:RTN1(gene name)|psi-mi:RTN1(display_short)	psi-mi:manf_human(display_long)|uniprotkb:Protein ARMET(gene name synonym)|uniprotkb:ARMET(gene name synonym)|uniprotkb:ARP(gene name synonym)|uniprotkb:MANF(gene name)|psi-mi:MANF(display_short)|uniprotkb:Arginine-rich protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Chen et al. (2015)	pubmed:25543119|imex:IM-26975	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21368759|imex:IM-26975-36	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000139970(gene)|ensembl:ENST00000342503(transcript)|intact:EBI-742130(isoform-parent)|uniprotkb:Q16799-3(isoform-parent)	ensembl:ENSG00000145050(gene)|ensembl:ENST00000528157(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008083"(growth factor activity)|go:"GO:0031175"(neuron projection development)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0120146"(sulfatide binding)|go:"GO:1905897"(regulation of response to endoplasmic reticulum stress)|interpro:IPR019345|interpro:IPR036361|rcsb pdb:2KVD|rcsb pdb:2KVE|rcsb pdb:2W51|reactome:R-HSA-114608|refseq:NP_006001.4	-	-	-	figure legend:Table 1-2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2019/04/09	2019/04/29	rogid:geQCjvDNlu02XMSdhJirbuxDgh89606	rogid:6MhPWttVgDJsaGyg0sXn/tBXpCQ9606	rigid:CYjIeKRWoYRXGpkSq5xVid6P8OI	false	sufficient binding region:1-20	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q16799-3	uniprotkb:Q8NFW8-1	intact:EBI-10180131|ensembl:ENSP00000340716	intact:EBI-21368775|ensembl:ENSP00000229329	psi-mi:q16799-3(display_long)|uniprotkb:NSP(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)|uniprotkb:NSP-C(isoform synonym)|uniprotkb:RTN1(gene name)|psi-mi:RTN1(display_short)	psi-mi:q8nfw8-1(display_long)|uniprotkb:CMP-N-acetylneuraminic acid synthase(gene name synonym)|uniprotkb:CMAS(gene name)|psi-mi:CMAS(display_short)	psi-mi:"MI:0018"(two hybrid)	Chen et al. (2015)	pubmed:25543119|imex:IM-26975	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21368765|imex:IM-26975-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000139970(gene)|ensembl:ENST00000342503(transcript)|intact:EBI-742130(isoform-parent)|uniprotkb:Q16799-3(isoform-parent)	ensembl:ENSG00000111726(gene)|ensembl:ENST00000229329(transcript)|intact:EBI-2816175(isoform-parent)	-	-	-	figure legend:Table 1-3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2019/04/09	2019/04/29	rogid:geQCjvDNlu02XMSdhJirbuxDgh89606	rogid:N8On3mF4lrgjWtwXAwzmhpUZXn49606	rigid:cJCOe28ijHoAK6nKW+sW8jc3+tY	false	sufficient binding region:1-20	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13439-5	uniprotkb:Q16799-3	intact:EBI-21368801|ensembl:ENSP00000349305	intact:EBI-10180131|ensembl:ENSP00000340716	psi-mi:q13439-5(display_long)|uniprotkb:256 kDa golgin(gene name synonym)|uniprotkb:Golgin-245(gene name synonym)|uniprotkb:Protein 72.1(gene name synonym)|uniprotkb:Trans-Golgi p230(gene name synonym)|uniprotkb:GOLGA4(gene name)|psi-mi:GOLGA4(display_short)	psi-mi:q16799-3(display_long)|uniprotkb:NSP(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)|uniprotkb:NSP-C(isoform synonym)|uniprotkb:RTN1(gene name)|psi-mi:RTN1(display_short)	psi-mi:"MI:0018"(two hybrid)	Chen et al. (2015)	pubmed:25543119|imex:IM-26975	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21368781|imex:IM-26975-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1037845(isoform-parent)|ensembl:ENSG00000144674(gene)|ensembl:ENST00000356847(transcript)	ensembl:ENSG00000139970(gene)|ensembl:ENST00000342503(transcript)|intact:EBI-742130(isoform-parent)|uniprotkb:Q16799-3(isoform-parent)	-	isoform-comment:No experimental confirmation available.	-	figure legend:Table 1-4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2019/04/09	2019/04/29	rogid:9Ar6CevHY6+aLIM1gGPCI7hCBFU9606	rogid:geQCjvDNlu02XMSdhJirbuxDgh89606	rigid:rlvZ9tRwYn33WrXXKofizX1FwqI	false	-	sufficient binding region:1-20	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q16799-3	uniprotkb:P10909-1	intact:EBI-10180131|ensembl:ENSP00000340716	intact:EBI-21368810|ensembl:ENSP00000315130|ensembl:ENSP00000385419|ensembl:ENSP00000429620	psi-mi:q16799-3(display_long)|uniprotkb:NSP(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)|uniprotkb:NSP-C(isoform synonym)|uniprotkb:RTN1(gene name)|psi-mi:RTN1(display_short)	psi-mi:p10909-1(display_long)|uniprotkb:Aging-associated gene 4 protein(gene name synonym)|uniprotkb:Apolipoprotein J(gene name synonym)|uniprotkb:Complement cytolysis inhibitor(gene name synonym)|uniprotkb:Complement-associated protein SP-40,40(gene name synonym)|uniprotkb:Ku70-binding protein 1(gene name synonym)|uniprotkb:NA1/NA2(gene name synonym)|uniprotkb:Sulfated glycoprotein 2(gene name synonym)|uniprotkb:Testosterone-repressed prostate message 2(gene name synonym)|uniprotkb:AAG4(orf name)|uniprotkb:2(isoform synonym)|uniprotkb:CLU35(isoform synonym)|uniprotkb:sCLU(isoform synonym)|uniprotkb:CLU(gene name)|psi-mi:CLU(display_short)|uniprotkb:APOJ(gene name synonym)|uniprotkb:CLI(gene name synonym)|uniprotkb:KUB1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Chen et al. (2015)	pubmed:25543119|imex:IM-26975	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21368794|imex:IM-26975-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000139970(gene)|ensembl:ENST00000342503(transcript)|intact:EBI-742130(isoform-parent)|uniprotkb:Q16799-3(isoform-parent)	ensembl:ENSG00000120885(gene)|ensembl:ENST00000316403(transcript)|ensembl:ENST00000405140(transcript)|ensembl:ENST00000523500(transcript)|intact:EBI-1104674(isoform-parent)	-	-	isoform-comment:"Major isoform. Major isoform. Detectable at protein level in stressed and unstressed cells (Ref.3)."	figure legend:Table 1-5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2019/04/09	2019/04/29	rogid:geQCjvDNlu02XMSdhJirbuxDgh89606	rogid:qlCJp4zYTklC3YZNQvbLmZBiz4U9606	rigid:CzPR72b+YyBFdDgGpu35O/0HkUY	false	sufficient binding region:1-20	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q16799-3	uniprotkb:Q13616	intact:EBI-10180131|ensembl:ENSP00000340716	intact:EBI-359390|uniprotkb:O60719|uniprotkb:Q08AL6|uniprotkb:Q8IYW1|uniprotkb:D3DWG3|ensembl:ENSP00000326804|ensembl:ENSP00000387160|ensembl:ENSP00000473318|ensembl:ENSP00000499255|ensembl:ENSP00000499277|ensembl:ENSP00000499398	psi-mi:q16799-3(display_long)|uniprotkb:NSP(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)|uniprotkb:NSP-C(isoform synonym)|uniprotkb:RTN1(gene name)|psi-mi:RTN1(display_short)	psi-mi:cul1_human(display_long)|uniprotkb:CUL1(gene name)|psi-mi:CUL1(display_short)	psi-mi:"MI:0018"(two hybrid)	Chen et al. (2015)	pubmed:25543119|imex:IM-26975	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21368823|imex:IM-26975-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000139970(gene)|ensembl:ENST00000342503(transcript)|intact:EBI-742130(isoform-parent)|uniprotkb:Q16799-3(isoform-parent)	refseq:NP_003583.2|rcsb pdb:6WCQ|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7B5R|rcsb pdb:7B5S|reactome:R-HSA-1169091|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|refseq:XP_011514931.1|refseq:XP_011514932.1|refseq:XP_011514933.1|refseq:XP_011514934.1|ensembl:ENSG00000055130(gene)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|ensembl:ENST00000325222(transcript)|ensembl:ENST00000409469(transcript)|ensembl:ENST00000602748(transcript)|ensembl:ENST00000662716(transcript)|ensembl:ENST00000663044(transcript)|ensembl:ENST00000665936(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13616|rcsb pdb:1LDJ|rcsb pdb:1LDK|rcsb pdb:1U6G|rcsb pdb:3RTR|rcsb pdb:3TDU|rcsb pdb:3TDZ|rcsb pdb:4F52|rcsb pdb:4P5O|rcsb pdb:5V89|rcsb pdb:6TTU|refseq:XP_005250117.1|dip:DIP-17013N	-	-	-	figure legend:Table 1-6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2019/04/09	2019/04/29	rogid:geQCjvDNlu02XMSdhJirbuxDgh89606	rogid:OAZP+ifWW3eEnQKb937ww9s1fMQ9606	rigid:fqErNBkvkb54VykgAVNzQvy+q4g	false	sufficient binding region:1-20	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q16799-3	uniprotkb:P60900-1	intact:EBI-10180131|ensembl:ENSP00000340716	intact:EBI-21368835|ensembl:ENSP00000261479	psi-mi:q16799-3(display_long)|uniprotkb:NSP(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)|uniprotkb:NSP-C(isoform synonym)|uniprotkb:RTN1(gene name)|psi-mi:RTN1(display_short)	psi-mi:p60900-1(display_long)|uniprotkb:27 kDa prosomal protein(gene name synonym)|uniprotkb:Macropain iota chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex iota chain(gene name synonym)|uniprotkb:Proteasome iota chain(gene name synonym)|uniprotkb:PSMA6(gene name)|psi-mi:PSMA6(display_short)|uniprotkb:PROS27(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Chen et al. (2015)	pubmed:25543119|imex:IM-26975	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21368829|imex:IM-26975-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000139970(gene)|ensembl:ENST00000342503(transcript)|intact:EBI-742130(isoform-parent)|uniprotkb:Q16799-3(isoform-parent)	ensembl:ENSG00000100902(gene)|ensembl:ENST00000261479(transcript)|intact:EBI-357793(isoform-parent)	-	-	-	figure legend:Table 1-7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2019/04/09	2019/04/29	rogid:geQCjvDNlu02XMSdhJirbuxDgh89606	rogid:F+Kwr6rnDS3jD53gBGHDIn7HV/89606	rigid:pj283rTK9myi6irLIrvZMumxUrY	false	sufficient binding region:1-20	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q16799-3	uniprotkb:Q16739	intact:EBI-10180131|ensembl:ENSP00000340716	intact:EBI-11151247|uniprotkb:Q5T258|ensembl:ENSP00000363397	psi-mi:q16799-3(display_long)|uniprotkb:NSP(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)|uniprotkb:NSP-C(isoform synonym)|uniprotkb:RTN1(gene name)|psi-mi:RTN1(display_short)	psi-mi:cegt_human(display_long)|uniprotkb:UGCG(gene name)|psi-mi:UGCG(display_short)|uniprotkb:GLCT-1(gene name synonym)|uniprotkb:Glucosylceramide synthase(gene name synonym)|uniprotkb:UDP-glucose ceramide glucosyltransferase(gene name synonym)|uniprotkb:"UDP-glucose:N-acylsphingosine D-glucosyltransferase"(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Chen et al. (2015)	pubmed:25543119|imex:IM-26975	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21405433|imex:IM-26975-38	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000139970(gene)|ensembl:ENST00000342503(transcript)|intact:EBI-742130(isoform-parent)|uniprotkb:Q16799-3(isoform-parent)	refseq:NP_003349.1|ensembl:ENSG00000148154(gene)|ensembl:ENST00000374279(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0006497"(protein lipidation)|go:"GO:0006687"(glycosphingolipid metabolic process)|go:"GO:0008120"(ceramide glucosyltransferase activity)|go:"GO:0008544"(epidermis development)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0048666"(neuron development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0098856"(intestinal lipid absorption)|go:"GO:0102769"(dihydroceramide glucosyltransferase activity)|go:"GO:1903575"(cornified envelope assembly)|interpro:IPR025993|interpro:IPR029044|reactome:R-HSA-1660662|go:"GO:0006679"(glucosylceramide biosynthetic process)	-	-	-	figure legend:Table 1-1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2019/04/09	2019/05/22	rogid:geQCjvDNlu02XMSdhJirbuxDgh89606	rogid:oC4p6jpq7h3KOPQAlqkjezUP6j09606	rigid:zbz8UmpPK903KKHiuR38oPtpELE	false	sufficient binding region:1-20	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q16799-3	uniprotkb:Q16739	intact:EBI-10180131|ensembl:ENSP00000340716	intact:EBI-11151247|uniprotkb:Q5T258|ensembl:ENSP00000363397	psi-mi:q16799-3(display_long)|uniprotkb:NSP(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)|uniprotkb:NSP-C(isoform synonym)|uniprotkb:RTN1(gene name)|psi-mi:RTN1(display_short)	psi-mi:cegt_human(display_long)|uniprotkb:UGCG(gene name)|psi-mi:UGCG(display_short)|uniprotkb:GLCT-1(gene name synonym)|uniprotkb:Glucosylceramide synthase(gene name synonym)|uniprotkb:UDP-glucose ceramide glucosyltransferase(gene name synonym)|uniprotkb:"UDP-glucose:N-acylsphingosine D-glucosyltransferase"(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Chen et al. (2015)	pubmed:25543119|imex:IM-26975	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21368741|imex:IM-26975-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000139970(gene)|ensembl:ENST00000342503(transcript)|intact:EBI-742130(isoform-parent)|uniprotkb:Q16799-3(isoform-parent)	refseq:NP_003349.1|ensembl:ENSG00000148154(gene)|ensembl:ENST00000374279(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0006497"(protein lipidation)|go:"GO:0006687"(glycosphingolipid metabolic process)|go:"GO:0008120"(ceramide glucosyltransferase activity)|go:"GO:0008544"(epidermis development)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0048666"(neuron development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0098856"(intestinal lipid absorption)|go:"GO:0102769"(dihydroceramide glucosyltransferase activity)|go:"GO:1903575"(cornified envelope assembly)|interpro:IPR025993|interpro:IPR029044|reactome:R-HSA-1660662|go:"GO:0006679"(glucosylceramide biosynthetic process)	-	-	-	figure legend:Figure 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2019/04/09	2019/04/29	rogid:geQCjvDNlu02XMSdhJirbuxDgh89606	rogid:oC4p6jpq7h3KOPQAlqkjezUP6j09606	rigid:zbz8UmpPK903KKHiuR38oPtpELE	false	sufficient binding region:1-20	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q16799-3	uniprotkb:Q8NFW8-1	intact:EBI-10180131|ensembl:ENSP00000340716	intact:EBI-21368775|ensembl:ENSP00000229329	psi-mi:q16799-3(display_long)|uniprotkb:NSP(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)|uniprotkb:NSP-C(isoform synonym)|uniprotkb:RTN1(gene name)|psi-mi:RTN1(display_short)	psi-mi:q8nfw8-1(display_long)|uniprotkb:CMP-N-acetylneuraminic acid synthase(gene name synonym)|uniprotkb:CMAS(gene name)|psi-mi:CMAS(display_short)	psi-mi:"MI:0018"(two hybrid)	Chen et al. (2015)	pubmed:25543119|imex:IM-26975	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21368855|imex:IM-26975-29	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000139970(gene)|ensembl:ENST00000342503(transcript)|intact:EBI-742130(isoform-parent)|uniprotkb:Q16799-3(isoform-parent)	ensembl:ENSG00000111726(gene)|ensembl:ENST00000229329(transcript)|intact:EBI-2816175(isoform-parent)	-	-	-	figure legend:Figure 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2019/04/09	2019/04/29	rogid:geQCjvDNlu02XMSdhJirbuxDgh89606	rogid:N8On3mF4lrgjWtwXAwzmhpUZXn49606	rigid:cJCOe28ijHoAK6nKW+sW8jc3+tY	false	sufficient binding region:1-20	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13439-5	uniprotkb:Q16799-3	intact:EBI-21368801|ensembl:ENSP00000349305	intact:EBI-10180131|ensembl:ENSP00000340716	psi-mi:q13439-5(display_long)|uniprotkb:256 kDa golgin(gene name synonym)|uniprotkb:Golgin-245(gene name synonym)|uniprotkb:Protein 72.1(gene name synonym)|uniprotkb:Trans-Golgi p230(gene name synonym)|uniprotkb:GOLGA4(gene name)|psi-mi:GOLGA4(display_short)	psi-mi:q16799-3(display_long)|uniprotkb:NSP(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)|uniprotkb:NSP-C(isoform synonym)|uniprotkb:RTN1(gene name)|psi-mi:RTN1(display_short)	psi-mi:"MI:0018"(two hybrid)	Chen et al. (2015)	pubmed:25543119|imex:IM-26975	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21368867|imex:IM-26975-31	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1037845(isoform-parent)|ensembl:ENSG00000144674(gene)|ensembl:ENST00000356847(transcript)	ensembl:ENSG00000139970(gene)|ensembl:ENST00000342503(transcript)|intact:EBI-742130(isoform-parent)|uniprotkb:Q16799-3(isoform-parent)	-	isoform-comment:No experimental confirmation available.	-	figure legend:Figure 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2019/04/09	2019/04/29	rogid:9Ar6CevHY6+aLIM1gGPCI7hCBFU9606	rogid:geQCjvDNlu02XMSdhJirbuxDgh89606	rigid:rlvZ9tRwYn33WrXXKofizX1FwqI	false	-	sufficient binding region:1-20	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q16799-3	uniprotkb:P10909-1	intact:EBI-10180131|ensembl:ENSP00000340716	intact:EBI-21368810|ensembl:ENSP00000315130|ensembl:ENSP00000385419|ensembl:ENSP00000429620	psi-mi:q16799-3(display_long)|uniprotkb:NSP(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)|uniprotkb:NSP-C(isoform synonym)|uniprotkb:RTN1(gene name)|psi-mi:RTN1(display_short)	psi-mi:p10909-1(display_long)|uniprotkb:Aging-associated gene 4 protein(gene name synonym)|uniprotkb:Apolipoprotein J(gene name synonym)|uniprotkb:Complement cytolysis inhibitor(gene name synonym)|uniprotkb:Complement-associated protein SP-40,40(gene name synonym)|uniprotkb:Ku70-binding protein 1(gene name synonym)|uniprotkb:NA1/NA2(gene name synonym)|uniprotkb:Sulfated glycoprotein 2(gene name synonym)|uniprotkb:Testosterone-repressed prostate message 2(gene name synonym)|uniprotkb:AAG4(orf name)|uniprotkb:2(isoform synonym)|uniprotkb:CLU35(isoform synonym)|uniprotkb:sCLU(isoform synonym)|uniprotkb:CLU(gene name)|psi-mi:CLU(display_short)|uniprotkb:APOJ(gene name synonym)|uniprotkb:CLI(gene name synonym)|uniprotkb:KUB1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Chen et al. (2015)	pubmed:25543119|imex:IM-26975	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21368879|imex:IM-26975-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000139970(gene)|ensembl:ENST00000342503(transcript)|intact:EBI-742130(isoform-parent)|uniprotkb:Q16799-3(isoform-parent)	ensembl:ENSG00000120885(gene)|ensembl:ENST00000316403(transcript)|ensembl:ENST00000405140(transcript)|ensembl:ENST00000523500(transcript)|intact:EBI-1104674(isoform-parent)	-	-	isoform-comment:"Major isoform. Major isoform. Detectable at protein level in stressed and unstressed cells (Ref.3)."	figure legend:Figure 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2019/04/09	2019/04/29	rogid:geQCjvDNlu02XMSdhJirbuxDgh89606	rogid:qlCJp4zYTklC3YZNQvbLmZBiz4U9606	rigid:CzPR72b+YyBFdDgGpu35O/0HkUY	false	sufficient binding region:1-20	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q16799-3	uniprotkb:P55145	intact:EBI-10180131|ensembl:ENSP00000340716	intact:EBI-1044104|uniprotkb:Q14CX4|uniprotkb:Q86U67|uniprotkb:Q96IS4|ensembl:ENSP00000432799	psi-mi:q16799-3(display_long)|uniprotkb:NSP(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)|uniprotkb:NSP-C(isoform synonym)|uniprotkb:RTN1(gene name)|psi-mi:RTN1(display_short)	psi-mi:manf_human(display_long)|uniprotkb:Protein ARMET(gene name synonym)|uniprotkb:ARMET(gene name synonym)|uniprotkb:ARP(gene name synonym)|uniprotkb:MANF(gene name)|psi-mi:MANF(display_short)|uniprotkb:Arginine-rich protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Chen et al. (2015)	pubmed:25543119|imex:IM-26975	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21368873|imex:IM-26975-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000139970(gene)|ensembl:ENST00000342503(transcript)|intact:EBI-742130(isoform-parent)|uniprotkb:Q16799-3(isoform-parent)	ensembl:ENSG00000145050(gene)|ensembl:ENST00000528157(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008083"(growth factor activity)|go:"GO:0031175"(neuron projection development)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0120146"(sulfatide binding)|go:"GO:1905897"(regulation of response to endoplasmic reticulum stress)|interpro:IPR019345|interpro:IPR036361|rcsb pdb:2KVD|rcsb pdb:2KVE|rcsb pdb:2W51|reactome:R-HSA-114608|refseq:NP_006001.4	-	-	-	figure legend:Figure 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2019/04/09	2019/04/29	rogid:geQCjvDNlu02XMSdhJirbuxDgh89606	rogid:6MhPWttVgDJsaGyg0sXn/tBXpCQ9606	rigid:CYjIeKRWoYRXGpkSq5xVid6P8OI	false	sufficient binding region:1-20	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q16799-3	uniprotkb:Q13616	intact:EBI-10180131|ensembl:ENSP00000340716	intact:EBI-359390|uniprotkb:O60719|uniprotkb:Q08AL6|uniprotkb:Q8IYW1|uniprotkb:D3DWG3|ensembl:ENSP00000326804|ensembl:ENSP00000387160|ensembl:ENSP00000473318|ensembl:ENSP00000499255|ensembl:ENSP00000499277|ensembl:ENSP00000499398	psi-mi:q16799-3(display_long)|uniprotkb:NSP(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)|uniprotkb:NSP-C(isoform synonym)|uniprotkb:RTN1(gene name)|psi-mi:RTN1(display_short)	psi-mi:cul1_human(display_long)|uniprotkb:CUL1(gene name)|psi-mi:CUL1(display_short)	psi-mi:"MI:0018"(two hybrid)	Chen et al. (2015)	pubmed:25543119|imex:IM-26975	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21368885|imex:IM-26975-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000139970(gene)|ensembl:ENST00000342503(transcript)|intact:EBI-742130(isoform-parent)|uniprotkb:Q16799-3(isoform-parent)	refseq:NP_003583.2|rcsb pdb:6WCQ|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7B5R|rcsb pdb:7B5S|reactome:R-HSA-1169091|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|refseq:XP_011514931.1|refseq:XP_011514932.1|refseq:XP_011514933.1|refseq:XP_011514934.1|ensembl:ENSG00000055130(gene)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|ensembl:ENST00000325222(transcript)|ensembl:ENST00000409469(transcript)|ensembl:ENST00000602748(transcript)|ensembl:ENST00000662716(transcript)|ensembl:ENST00000663044(transcript)|ensembl:ENST00000665936(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13616|rcsb pdb:1LDJ|rcsb pdb:1LDK|rcsb pdb:1U6G|rcsb pdb:3RTR|rcsb pdb:3TDU|rcsb pdb:3TDZ|rcsb pdb:4F52|rcsb pdb:4P5O|rcsb pdb:5V89|rcsb pdb:6TTU|refseq:XP_005250117.1|dip:DIP-17013N	-	-	-	figure legend:Figure 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2019/04/09	2019/04/29	rogid:geQCjvDNlu02XMSdhJirbuxDgh89606	rogid:OAZP+ifWW3eEnQKb937ww9s1fMQ9606	rigid:fqErNBkvkb54VykgAVNzQvy+q4g	false	sufficient binding region:1-20	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q16799-3	uniprotkb:P60900-1	intact:EBI-10180131|ensembl:ENSP00000340716	intact:EBI-21368835|ensembl:ENSP00000261479	psi-mi:q16799-3(display_long)|uniprotkb:NSP(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)|uniprotkb:NSP-C(isoform synonym)|uniprotkb:RTN1(gene name)|psi-mi:RTN1(display_short)	psi-mi:p60900-1(display_long)|uniprotkb:27 kDa prosomal protein(gene name synonym)|uniprotkb:Macropain iota chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex iota chain(gene name synonym)|uniprotkb:Proteasome iota chain(gene name synonym)|uniprotkb:PSMA6(gene name)|psi-mi:PSMA6(display_short)|uniprotkb:PROS27(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Chen et al. (2015)	pubmed:25543119|imex:IM-26975	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21368861|imex:IM-26975-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000139970(gene)|ensembl:ENST00000342503(transcript)|intact:EBI-742130(isoform-parent)|uniprotkb:Q16799-3(isoform-parent)	ensembl:ENSG00000100902(gene)|ensembl:ENST00000261479(transcript)|intact:EBI-357793(isoform-parent)	-	-	-	figure legend:Figure 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2019/04/09	2019/04/29	rogid:geQCjvDNlu02XMSdhJirbuxDgh89606	rogid:F+Kwr6rnDS3jD53gBGHDIn7HV/89606	rigid:pj283rTK9myi6irLIrvZMumxUrY	false	sufficient binding region:1-20	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q16799-3	uniprotkb:P55145	intact:EBI-10180131|ensembl:ENSP00000340716	intact:EBI-1044104|uniprotkb:Q14CX4|uniprotkb:Q86U67|uniprotkb:Q96IS4|ensembl:ENSP00000432799	psi-mi:q16799-3(display_long)|uniprotkb:NSP(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)|uniprotkb:NSP-C(isoform synonym)|uniprotkb:RTN1(gene name)|psi-mi:RTN1(display_short)	psi-mi:manf_human(display_long)|uniprotkb:Protein ARMET(gene name synonym)|uniprotkb:ARMET(gene name synonym)|uniprotkb:ARP(gene name synonym)|uniprotkb:MANF(gene name)|psi-mi:MANF(display_short)|uniprotkb:Arginine-rich protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chen et al. (2015)	pubmed:25543119|imex:IM-26975	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21368917|imex:IM-26975-33	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000139970(gene)|ensembl:ENST00000342503(transcript)|intact:EBI-742130(isoform-parent)|uniprotkb:Q16799-3(isoform-parent)	ensembl:ENSG00000145050(gene)|ensembl:ENST00000528157(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008083"(growth factor activity)|go:"GO:0031175"(neuron projection development)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0120146"(sulfatide binding)|go:"GO:1905897"(regulation of response to endoplasmic reticulum stress)|interpro:IPR019345|interpro:IPR036361|rcsb pdb:2KVD|rcsb pdb:2KVE|rcsb pdb:2W51|reactome:R-HSA-114608|refseq:NP_006001.4	-	-	-	figure legend:Figure 3B|comment:Figure 3A shows a C-terminal GST tag on RTN1-C, however the  pGEX6P-1 vector stated to have been used has an N-terminal GST tag.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/09	2019/05/22	rogid:geQCjvDNlu02XMSdhJirbuxDgh89606	rogid:6MhPWttVgDJsaGyg0sXn/tBXpCQ9606	rigid:CYjIeKRWoYRXGpkSq5xVid6P8OI	false	glutathione s tranferase tag:n-n	his tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q16799-3	uniprotkb:P55145	intact:EBI-10180131|ensembl:ENSP00000340716	intact:EBI-1044104|uniprotkb:Q14CX4|uniprotkb:Q86U67|uniprotkb:Q96IS4|ensembl:ENSP00000432799	psi-mi:q16799-3(display_long)|uniprotkb:NSP(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)|uniprotkb:NSP-C(isoform synonym)|uniprotkb:RTN1(gene name)|psi-mi:RTN1(display_short)	psi-mi:manf_human(display_long)|uniprotkb:Protein ARMET(gene name synonym)|uniprotkb:ARMET(gene name synonym)|uniprotkb:ARP(gene name synonym)|uniprotkb:MANF(gene name)|psi-mi:MANF(display_short)|uniprotkb:Arginine-rich protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chen et al. (2015)	pubmed:25543119|imex:IM-26975	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21368941|imex:IM-26975-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000139970(gene)|ensembl:ENST00000342503(transcript)|intact:EBI-742130(isoform-parent)|uniprotkb:Q16799-3(isoform-parent)	ensembl:ENSG00000145050(gene)|ensembl:ENST00000528157(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008083"(growth factor activity)|go:"GO:0031175"(neuron projection development)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0120146"(sulfatide binding)|go:"GO:1905897"(regulation of response to endoplasmic reticulum stress)|interpro:IPR019345|interpro:IPR036361|rcsb pdb:2KVD|rcsb pdb:2KVE|rcsb pdb:2W51|reactome:R-HSA-114608|refseq:NP_006001.4	-	-	-	figure legend:Figure 4A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-neuro_2_a)|taxid:10090("Mus musculus albino neuroblastoma cell line neuro 2 a (N2a)")	-	2019/04/09	2019/04/30	rogid:geQCjvDNlu02XMSdhJirbuxDgh89606	rogid:6MhPWttVgDJsaGyg0sXn/tBXpCQ9606	rigid:CYjIeKRWoYRXGpkSq5xVid6P8OI	false	flag tag:n-n|myc tag:c-c	enhanced green fluorescent protein tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q16799	uniprotkb:P55145	intact:EBI-742130|uniprotkb:Q16800|uniprotkb:Q16801|uniprotkb:Q5BKZ4|intact:EBI-2801527|uniprotkb:Q9BQ59|ensembl:ENSP00000267484	intact:EBI-1044104|uniprotkb:Q14CX4|uniprotkb:Q86U67|uniprotkb:Q96IS4|ensembl:ENSP00000432799	psi-mi:rtn1_human(display_long)|uniprotkb:RTN1(gene name)|psi-mi:RTN1(display_short)|uniprotkb:NSP(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)	psi-mi:manf_human(display_long)|uniprotkb:Protein ARMET(gene name synonym)|uniprotkb:ARMET(gene name synonym)|uniprotkb:ARP(gene name synonym)|uniprotkb:MANF(gene name)|psi-mi:MANF(display_short)|uniprotkb:Arginine-rich protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Chen et al. (2015)	pubmed:25543119|imex:IM-26975	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21368964|imex:IM-26975-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_066959.1|refseq:NP_996734.1|ensembl:ENSG00000139970(gene)|ensembl:ENST00000267484(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|interpro:IPR003388(Reticulon)|mint:Q16799	ensembl:ENSG00000145050(gene)|ensembl:ENST00000528157(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008083"(growth factor activity)|go:"GO:0031175"(neuron projection development)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0120146"(sulfatide binding)|go:"GO:1905897"(regulation of response to endoplasmic reticulum stress)|interpro:IPR019345|interpro:IPR036361|rcsb pdb:2KVD|rcsb pdb:2KVE|rcsb pdb:2W51|reactome:R-HSA-114608|refseq:NP_006001.4	-	-	-	figure legend:Figure 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-sh_sy5y)|taxid:9606(Homo sapiens SH-SY5Y cell line)	-	2019/04/09	2019/04/30	rogid:oBpsOfx4vuPEjlUg5McyYDfqKzo9606	rogid:6MhPWttVgDJsaGyg0sXn/tBXpCQ9606	rigid:H35/SqeNLX3nQxjWFVjt/FonvMs	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P55145	uniprotkb:Q16799	intact:EBI-1044104|uniprotkb:Q14CX4|uniprotkb:Q86U67|uniprotkb:Q96IS4|ensembl:ENSP00000432799	intact:EBI-742130|uniprotkb:Q16800|uniprotkb:Q16801|uniprotkb:Q5BKZ4|intact:EBI-2801527|uniprotkb:Q9BQ59|ensembl:ENSP00000267484	psi-mi:manf_human(display_long)|uniprotkb:Protein ARMET(gene name synonym)|uniprotkb:ARMET(gene name synonym)|uniprotkb:ARP(gene name synonym)|uniprotkb:MANF(gene name)|psi-mi:MANF(display_short)|uniprotkb:Arginine-rich protein(gene name synonym)	psi-mi:rtn1_human(display_long)|uniprotkb:RTN1(gene name)|psi-mi:RTN1(display_short)|uniprotkb:NSP(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Chen et al. (2015)	pubmed:25543119|imex:IM-26975	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21368985|imex:IM-26975-35	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000145050(gene)|ensembl:ENST00000528157(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008083"(growth factor activity)|go:"GO:0031175"(neuron projection development)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0120146"(sulfatide binding)|go:"GO:1905897"(regulation of response to endoplasmic reticulum stress)|interpro:IPR019345|interpro:IPR036361|rcsb pdb:2KVD|rcsb pdb:2KVE|rcsb pdb:2W51|reactome:R-HSA-114608|refseq:NP_006001.4	refseq:NP_066959.1|refseq:NP_996734.1|ensembl:ENSG00000139970(gene)|ensembl:ENST00000267484(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|interpro:IPR003388(Reticulon)|mint:Q16799	go:"GO:0005783"(endoplasmic reticulum)	-	-	figure legend:Figure 5A,6A|comment:The loss of MANF staining in ER is the specific consequence of depletion of RTN1-C.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-sh_sy5y)|taxid:9606(Homo sapiens SH-SY5Y cell line)	-	2019/04/09	2019/04/30	rogid:6MhPWttVgDJsaGyg0sXn/tBXpCQ9606	rogid:oBpsOfx4vuPEjlUg5McyYDfqKzo9606	rigid:H35/SqeNLX3nQxjWFVjt/FonvMs	false	-	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)