#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q13133 uniprotkb:Q07869 intact:EBI-781356|uniprotkb:A8K3J9|uniprotkb:Q96H87|uniprotkb:D3DQR1|uniprotkb:Q8IW13|ensembl:ENSP00000387946|ensembl:ENSP00000420656 intact:EBI-78615|uniprotkb:Q16241|uniprotkb:Q92486|uniprotkb:Q92689|uniprotkb:Q9Y3N1|ensembl:ENSP00000262735|ensembl:ENSP00000385246|ensembl:ENSP00000385523|uniprotkb:Q6I9S0|uniprotkb:B0G0X3 psi-mi:nr1h3_human(display_long)|uniprotkb:Liver X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group H member 3(gene name synonym)|uniprotkb:NR1H3(gene name)|psi-mi:NR1H3(display_short)|uniprotkb:LXRA(gene name synonym) psi-mi:ppara_human(display_long)|uniprotkb:PPARA(gene name)|psi-mi:PPARA(display_short)|uniprotkb:NR1C1(gene name synonym)|uniprotkb:PPAR(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group C member 1(gene name synonym) psi-mi:"MI:0016"(circular dichroism) Balanarasimha et al. (2014) imex:IM-27148|pubmed:24713062 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-21446333|imex:IM-27148-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006718175.1|refseq:XP_006718176.1|refseq:XP_006718178.1|refseq:XP_006718179.1|refseq:NP_001123574.1|refseq:NP_001123573.1|refseq:NP_005684.2|refseq:XP_011518107.1|refseq:XP_005252770.1|refseq:XP_005252762.1|refseq:XP_005252763.1|refseq:XP_005252764.1|refseq:XP_005252766.1|refseq:XP_005252767.1|refseq:XP_016872547.1|ensembl:ENSG00000025434(gene)|ensembl:ENST00000441012(transcript)|ensembl:ENST00000467728(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010867"(positive regulation of triglyceride biosynthetic process)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0015485"(cholesterol binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032369"(negative regulation of lipid transport)|go:"GO:0032376"(positive regulation of cholesterol transport)|go:"GO:0032411"(positive regulation of transporter activity)|go:"GO:0032570"(response to progesterone)|go:"GO:0032810"(sterol response element binding)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043031"(negative regulation of macrophage activation)|go:"GO:0043235"(receptor complex)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0090188"(negative regulation of pancreatic juice secretion)|go:"GO:0090341"(negative regulation of secretion of lysosomal enzymes)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1903573"(negative regulation of response to endoplasmic reticulum stress)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR023257|interpro:IPR035500|mint:Q13133|rcsb pdb:1UHL|rcsb pdb:3IPQ|rcsb pdb:3IPS|rcsb pdb:3IPU|rcsb pdb:5AVI|rcsb pdb:5AVL|rcsb pdb:5HJS|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8866427|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974 refseq:XP_005261712.1|refseq:XP_005261713.1|ensembl:ENSG00000186951(gene)|ensembl:ENST00000262735(transcript)|ensembl:ENST00000402126(transcript)|ensembl:ENST00000407236(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008144"(obsolete drug binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008289"(lipid binding)|go:"GO:0008544"(epidermis development)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010565"(regulation of cellular ketone metabolic process)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010876"(lipid localization)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0010891"(negative regulation of sequestering of triglyceride)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019217"(regulation of fatty acid metabolic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032000"(positive regulation of fatty acid beta-oxidation)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032099"(negative regulation of appetite)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033993"(response to lipid)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0042060"(wound healing)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070166"(enamel mineralization)|go:"GO:0045471"(response to ethanol)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045923"(positive regulation of fatty acid metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046321"(positive regulation of fatty acid oxidation)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051525"(NFAT protein binding)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|rcsb pdb:1I7G|go:"GO:0097371"(MDM2/MDM4 family protein binding)|rcsb pdb:1K7L|rcsb pdb:1KKQ|rcsb pdb:2NPA|rcsb pdb:2P54|rcsb pdb:2REW|rcsb pdb:2ZNN|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1903038"(negative regulation of leukocyte cell-cell adhesion)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1903944"(negative regulation of hepatocyte apoptotic process)|go:"GO:2000191"(regulation of fatty acid transport)|go:"GO:2000272"(negative regulation of signaling receptor activity)|rcsb pdb:3ET1|rcsb pdb:3FEI|rcsb pdb:3G8I|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003074(Peroxisome proliferator-activated receptor)|interpro:IPR003076(Peroxisome proliferator-activated receptor, alpha)|rcsb pdb:3KDT|interpro:IPR013088(Zinc finger, NHR/GATA-type)|rcsb pdb:3KDU|interpro:IPR035500|mint:Q07869|rcsb pdb:3SP6|rcsb pdb:3VI8|rcsb pdb:4BCR|rcsb pdb:4CI4|reactome:R-HSA-1989781|rcsb pdb:5AZT|reactome:R-HSA-2151201|reactome:R-HSA-2426168|rcsb pdb:5HYK|rcsb pdb:6KAX|reactome:R-HSA-381340|rcsb pdb:6KAY|rcsb pdb:6KAZ|reactome:R-HSA-383280|rcsb pdb:6KB0|reactome:R-HSA-400206|rcsb pdb:6KB1|rcsb pdb:6KB2|rcsb pdb:6KB3|rcsb pdb:6KB4|rcsb pdb:6KB5|reactome:R-HSA-400253|reactome:R-HSA-4090294|rcsb pdb:6KB6|reactome:R-HSA-9707564|reactome:R-HSA-9707616|rcsb pdb:6KB7|rcsb pdb:6KB8|rcsb pdb:6KB9|rcsb pdb:6KBA|rcsb pdb:6KXX|rcsb pdb:6KXY|rcsb pdb:6KYP|rcsb pdb:6L36|rcsb pdb:6L37|rcsb pdb:6L38|rcsb pdb:6L96|rcsb pdb:6LX4|rcsb pdb:6LX5|rcsb pdb:6LX6|rcsb pdb:6LX7|rcsb pdb:6LX8|rcsb pdb:6LX9|rcsb pdb:6LXA|rcsb pdb:6LXB|rcsb pdb:6LXC|rcsb pdb:7BPY|rcsb pdb:7BPZ|rcsb pdb:7BQ0|rcsb pdb:7BQ1|rcsb pdb:7BQ2|rcsb pdb:7BQ3|rcsb pdb:7BQ4|rcsb pdb:7C6Q|reactome:R-HSA-1368082|reactome:R-HSA-1368108|refseq:NP_001001928.1|refseq:NP_005027.2|refseq:XP_011528541.1|refseq:XP_011528542.1|refseq:XP_011528543.1|refseq:XP_011528544.1|refseq:XP_011528545.1|refseq:XP_006724332.1|refseq:XP_006724333.1|dip:DIP-241N - - - figure legend:Figure 2A,B, FIgure 5, Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/05/30 2019/07/04 rogid:o1qZ/nvjBXMWVvnnwindfL0HBFE9606 rogid:0ZZ5eL0cNC8OgOvd8spQ5ypBvAo9606 rigid:p6DMTorKHFPjanZVaVfasXWqv70 false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0113"(western blot) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0113"(western blot) uniprotkb:Q13133 uniprotkb:Q07869 intact:EBI-781356|uniprotkb:A8K3J9|uniprotkb:Q96H87|uniprotkb:D3DQR1|uniprotkb:Q8IW13|ensembl:ENSP00000387946|ensembl:ENSP00000420656 intact:EBI-78615|uniprotkb:Q16241|uniprotkb:Q92486|uniprotkb:Q92689|uniprotkb:Q9Y3N1|ensembl:ENSP00000262735|ensembl:ENSP00000385246|ensembl:ENSP00000385523|uniprotkb:Q6I9S0|uniprotkb:B0G0X3 psi-mi:nr1h3_human(display_long)|uniprotkb:Liver X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group H member 3(gene name synonym)|uniprotkb:NR1H3(gene name)|psi-mi:NR1H3(display_short)|uniprotkb:LXRA(gene name synonym) psi-mi:ppara_human(display_long)|uniprotkb:PPARA(gene name)|psi-mi:PPARA(display_short)|uniprotkb:NR1C1(gene name synonym)|uniprotkb:PPAR(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group C member 1(gene name synonym) psi-mi:"MI:0051"(fluorescence technology) Balanarasimha et al. (2014) imex:IM-27148|pubmed:24713062 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-21447754|imex:IM-27148-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006718175.1|refseq:XP_006718176.1|refseq:XP_006718178.1|refseq:XP_006718179.1|refseq:NP_001123574.1|refseq:NP_001123573.1|refseq:NP_005684.2|refseq:XP_011518107.1|refseq:XP_005252770.1|refseq:XP_005252762.1|refseq:XP_005252763.1|refseq:XP_005252764.1|refseq:XP_005252766.1|refseq:XP_005252767.1|refseq:XP_016872547.1|ensembl:ENSG00000025434(gene)|ensembl:ENST00000441012(transcript)|ensembl:ENST00000467728(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010867"(positive regulation of triglyceride biosynthetic process)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0015485"(cholesterol binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032369"(negative regulation of lipid transport)|go:"GO:0032376"(positive regulation of cholesterol transport)|go:"GO:0032411"(positive regulation of transporter activity)|go:"GO:0032570"(response to progesterone)|go:"GO:0032810"(sterol response element binding)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043031"(negative regulation of macrophage activation)|go:"GO:0043235"(receptor complex)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0090188"(negative regulation of pancreatic juice secretion)|go:"GO:0090341"(negative regulation of secretion of lysosomal enzymes)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1903573"(negative regulation of response to endoplasmic reticulum stress)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR023257|interpro:IPR035500|mint:Q13133|rcsb pdb:1UHL|rcsb pdb:3IPQ|rcsb pdb:3IPS|rcsb pdb:3IPU|rcsb pdb:5AVI|rcsb pdb:5AVL|rcsb pdb:5HJS|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8866427|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974 refseq:XP_005261712.1|refseq:XP_005261713.1|ensembl:ENSG00000186951(gene)|ensembl:ENST00000262735(transcript)|ensembl:ENST00000402126(transcript)|ensembl:ENST00000407236(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008144"(obsolete drug binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008289"(lipid binding)|go:"GO:0008544"(epidermis development)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010565"(regulation of cellular ketone metabolic process)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010876"(lipid localization)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0010891"(negative regulation of sequestering of triglyceride)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019217"(regulation of fatty acid metabolic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032000"(positive regulation of fatty acid beta-oxidation)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032099"(negative regulation of appetite)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033993"(response to lipid)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0042060"(wound healing)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070166"(enamel mineralization)|go:"GO:0045471"(response to ethanol)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045923"(positive regulation of fatty acid metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046321"(positive regulation of fatty acid oxidation)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051525"(NFAT protein binding)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|rcsb pdb:1I7G|go:"GO:0097371"(MDM2/MDM4 family protein binding)|rcsb pdb:1K7L|rcsb pdb:1KKQ|rcsb pdb:2NPA|rcsb pdb:2P54|rcsb pdb:2REW|rcsb pdb:2ZNN|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1903038"(negative regulation of leukocyte cell-cell adhesion)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1903944"(negative regulation of hepatocyte apoptotic process)|go:"GO:2000191"(regulation of fatty acid transport)|go:"GO:2000272"(negative regulation of signaling receptor activity)|rcsb pdb:3ET1|rcsb pdb:3FEI|rcsb pdb:3G8I|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003074(Peroxisome proliferator-activated receptor)|interpro:IPR003076(Peroxisome proliferator-activated receptor, alpha)|rcsb pdb:3KDT|interpro:IPR013088(Zinc finger, NHR/GATA-type)|rcsb pdb:3KDU|interpro:IPR035500|mint:Q07869|rcsb pdb:3SP6|rcsb pdb:3VI8|rcsb pdb:4BCR|rcsb pdb:4CI4|reactome:R-HSA-1989781|rcsb pdb:5AZT|reactome:R-HSA-2151201|reactome:R-HSA-2426168|rcsb pdb:5HYK|rcsb pdb:6KAX|reactome:R-HSA-381340|rcsb pdb:6KAY|rcsb pdb:6KAZ|reactome:R-HSA-383280|rcsb pdb:6KB0|reactome:R-HSA-400206|rcsb pdb:6KB1|rcsb pdb:6KB2|rcsb pdb:6KB3|rcsb pdb:6KB4|rcsb pdb:6KB5|reactome:R-HSA-400253|reactome:R-HSA-4090294|rcsb pdb:6KB6|reactome:R-HSA-9707564|reactome:R-HSA-9707616|rcsb pdb:6KB7|rcsb pdb:6KB8|rcsb pdb:6KB9|rcsb pdb:6KBA|rcsb pdb:6KXX|rcsb pdb:6KXY|rcsb pdb:6KYP|rcsb pdb:6L36|rcsb pdb:6L37|rcsb pdb:6L38|rcsb pdb:6L96|rcsb pdb:6LX4|rcsb pdb:6LX5|rcsb pdb:6LX6|rcsb pdb:6LX7|rcsb pdb:6LX8|rcsb pdb:6LX9|rcsb pdb:6LXA|rcsb pdb:6LXB|rcsb pdb:6LXC|rcsb pdb:7BPY|rcsb pdb:7BPZ|rcsb pdb:7BQ0|rcsb pdb:7BQ1|rcsb pdb:7BQ2|rcsb pdb:7BQ3|rcsb pdb:7BQ4|rcsb pdb:7C6Q|reactome:R-HSA-1368082|reactome:R-HSA-1368108|refseq:NP_001001928.1|refseq:NP_005027.2|refseq:XP_011528541.1|refseq:XP_011528542.1|refseq:XP_011528543.1|refseq:XP_011528544.1|refseq:XP_011528545.1|refseq:XP_006724332.1|refseq:XP_006724333.1|dip:DIP-241N - - - figure legend:Figure 3A, Figure 6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/05/30 2019/07/04 rogid:o1qZ/nvjBXMWVvnnwindfL0HBFE9606 rogid:0ZZ5eL0cNC8OgOvd8spQ5ypBvAo9606 rigid:p6DMTorKHFPjanZVaVfasXWqv70 false - cy5 label:?-? - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0113"(western blot) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0113"(western blot) uniprotkb:Q13133 uniprotkb:Q07869 intact:EBI-781356|uniprotkb:A8K3J9|uniprotkb:Q96H87|uniprotkb:D3DQR1|uniprotkb:Q8IW13|ensembl:ENSP00000387946|ensembl:ENSP00000420656 intact:EBI-78615|uniprotkb:Q16241|uniprotkb:Q92486|uniprotkb:Q92689|uniprotkb:Q9Y3N1|ensembl:ENSP00000262735|ensembl:ENSP00000385246|ensembl:ENSP00000385523|uniprotkb:Q6I9S0|uniprotkb:B0G0X3 psi-mi:nr1h3_human(display_long)|uniprotkb:Liver X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group H member 3(gene name synonym)|uniprotkb:NR1H3(gene name)|psi-mi:NR1H3(display_short)|uniprotkb:LXRA(gene name synonym) psi-mi:ppara_human(display_long)|uniprotkb:PPARA(gene name)|psi-mi:PPARA(display_short)|uniprotkb:NR1C1(gene name synonym)|uniprotkb:PPAR(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group C member 1(gene name synonym) psi-mi:"MI:0051"(fluorescence technology) Balanarasimha et al. (2014) imex:IM-27148|pubmed:24713062 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-21447760|imex:IM-27148-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006718175.1|refseq:XP_006718176.1|refseq:XP_006718178.1|refseq:XP_006718179.1|refseq:NP_001123574.1|refseq:NP_001123573.1|refseq:NP_005684.2|refseq:XP_011518107.1|refseq:XP_005252770.1|refseq:XP_005252762.1|refseq:XP_005252763.1|refseq:XP_005252764.1|refseq:XP_005252766.1|refseq:XP_005252767.1|refseq:XP_016872547.1|ensembl:ENSG00000025434(gene)|ensembl:ENST00000441012(transcript)|ensembl:ENST00000467728(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010867"(positive regulation of triglyceride biosynthetic process)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0015485"(cholesterol binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032369"(negative regulation of lipid transport)|go:"GO:0032376"(positive regulation of cholesterol transport)|go:"GO:0032411"(positive regulation of transporter activity)|go:"GO:0032570"(response to progesterone)|go:"GO:0032810"(sterol response element binding)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043031"(negative regulation of macrophage activation)|go:"GO:0043235"(receptor complex)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0090188"(negative regulation of pancreatic juice secretion)|go:"GO:0090341"(negative regulation of secretion of lysosomal enzymes)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1903573"(negative regulation of response to endoplasmic reticulum stress)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR023257|interpro:IPR035500|mint:Q13133|rcsb pdb:1UHL|rcsb pdb:3IPQ|rcsb pdb:3IPS|rcsb pdb:3IPU|rcsb pdb:5AVI|rcsb pdb:5AVL|rcsb pdb:5HJS|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8866427|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974 refseq:XP_005261712.1|refseq:XP_005261713.1|ensembl:ENSG00000186951(gene)|ensembl:ENST00000262735(transcript)|ensembl:ENST00000402126(transcript)|ensembl:ENST00000407236(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008144"(obsolete drug binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008289"(lipid binding)|go:"GO:0008544"(epidermis development)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010565"(regulation of cellular ketone metabolic process)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010876"(lipid localization)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0010891"(negative regulation of sequestering of triglyceride)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019217"(regulation of fatty acid metabolic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032000"(positive regulation of fatty acid beta-oxidation)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032099"(negative regulation of appetite)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033993"(response to lipid)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0042060"(wound healing)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070166"(enamel mineralization)|go:"GO:0045471"(response to ethanol)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045923"(positive regulation of fatty acid metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046321"(positive regulation of fatty acid oxidation)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051525"(NFAT protein binding)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|rcsb pdb:1I7G|go:"GO:0097371"(MDM2/MDM4 family protein binding)|rcsb pdb:1K7L|rcsb pdb:1KKQ|rcsb pdb:2NPA|rcsb pdb:2P54|rcsb pdb:2REW|rcsb pdb:2ZNN|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1903038"(negative regulation of leukocyte cell-cell adhesion)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1903944"(negative regulation of hepatocyte apoptotic process)|go:"GO:2000191"(regulation of fatty acid transport)|go:"GO:2000272"(negative regulation of signaling receptor activity)|rcsb pdb:3ET1|rcsb pdb:3FEI|rcsb pdb:3G8I|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003074(Peroxisome proliferator-activated receptor)|interpro:IPR003076(Peroxisome proliferator-activated receptor, alpha)|rcsb pdb:3KDT|interpro:IPR013088(Zinc finger, NHR/GATA-type)|rcsb pdb:3KDU|interpro:IPR035500|mint:Q07869|rcsb pdb:3SP6|rcsb pdb:3VI8|rcsb pdb:4BCR|rcsb pdb:4CI4|reactome:R-HSA-1989781|rcsb pdb:5AZT|reactome:R-HSA-2151201|reactome:R-HSA-2426168|rcsb pdb:5HYK|rcsb pdb:6KAX|reactome:R-HSA-381340|rcsb pdb:6KAY|rcsb pdb:6KAZ|reactome:R-HSA-383280|rcsb pdb:6KB0|reactome:R-HSA-400206|rcsb pdb:6KB1|rcsb pdb:6KB2|rcsb pdb:6KB3|rcsb pdb:6KB4|rcsb pdb:6KB5|reactome:R-HSA-400253|reactome:R-HSA-4090294|rcsb pdb:6KB6|reactome:R-HSA-9707564|reactome:R-HSA-9707616|rcsb pdb:6KB7|rcsb pdb:6KB8|rcsb pdb:6KB9|rcsb pdb:6KBA|rcsb pdb:6KXX|rcsb pdb:6KXY|rcsb pdb:6KYP|rcsb pdb:6L36|rcsb pdb:6L37|rcsb pdb:6L38|rcsb pdb:6L96|rcsb pdb:6LX4|rcsb pdb:6LX5|rcsb pdb:6LX6|rcsb pdb:6LX7|rcsb pdb:6LX8|rcsb pdb:6LX9|rcsb pdb:6LXA|rcsb pdb:6LXB|rcsb pdb:6LXC|rcsb pdb:7BPY|rcsb pdb:7BPZ|rcsb pdb:7BQ0|rcsb pdb:7BQ1|rcsb pdb:7BQ2|rcsb pdb:7BQ3|rcsb pdb:7BQ4|rcsb pdb:7C6Q|reactome:R-HSA-1368082|reactome:R-HSA-1368108|refseq:NP_001001928.1|refseq:NP_005027.2|refseq:XP_011528541.1|refseq:XP_011528542.1|refseq:XP_011528543.1|refseq:XP_011528544.1|refseq:XP_011528545.1|refseq:XP_006724332.1|refseq:XP_006724333.1|dip:DIP-241N - - - figure legend:Figure 3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/05/30 2019/07/04 rogid:o1qZ/nvjBXMWVvnnwindfL0HBFE9606 rogid:0ZZ5eL0cNC8OgOvd8spQ5ypBvAo9606 rigid:p6DMTorKHFPjanZVaVfasXWqv70 false cy3 label:?-? - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0113"(western blot) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0113"(western blot) uniprotkb:Q13133 uniprotkb:Q07869 intact:EBI-781356|uniprotkb:A8K3J9|uniprotkb:Q96H87|uniprotkb:D3DQR1|uniprotkb:Q8IW13|ensembl:ENSP00000387946|ensembl:ENSP00000420656 intact:EBI-78615|uniprotkb:Q16241|uniprotkb:Q92486|uniprotkb:Q92689|uniprotkb:Q9Y3N1|ensembl:ENSP00000262735|ensembl:ENSP00000385246|ensembl:ENSP00000385523|uniprotkb:Q6I9S0|uniprotkb:B0G0X3 psi-mi:nr1h3_human(display_long)|uniprotkb:Liver X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group H member 3(gene name synonym)|uniprotkb:NR1H3(gene name)|psi-mi:NR1H3(display_short)|uniprotkb:LXRA(gene name synonym) psi-mi:ppara_human(display_long)|uniprotkb:PPARA(gene name)|psi-mi:PPARA(display_short)|uniprotkb:NR1C1(gene name synonym)|uniprotkb:PPAR(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group C member 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Balanarasimha et al. (2014) imex:IM-27148|pubmed:24713062 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-21447777|imex:IM-27148-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006718175.1|refseq:XP_006718176.1|refseq:XP_006718178.1|refseq:XP_006718179.1|refseq:NP_001123574.1|refseq:NP_001123573.1|refseq:NP_005684.2|refseq:XP_011518107.1|refseq:XP_005252770.1|refseq:XP_005252762.1|refseq:XP_005252763.1|refseq:XP_005252764.1|refseq:XP_005252766.1|refseq:XP_005252767.1|refseq:XP_016872547.1|ensembl:ENSG00000025434(gene)|ensembl:ENST00000441012(transcript)|ensembl:ENST00000467728(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010867"(positive regulation of triglyceride biosynthetic process)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0015485"(cholesterol binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032369"(negative regulation of lipid transport)|go:"GO:0032376"(positive regulation of cholesterol transport)|go:"GO:0032411"(positive regulation of transporter activity)|go:"GO:0032570"(response to progesterone)|go:"GO:0032810"(sterol response element binding)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043031"(negative regulation of macrophage activation)|go:"GO:0043235"(receptor complex)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0090188"(negative regulation of pancreatic juice secretion)|go:"GO:0090341"(negative regulation of secretion of lysosomal enzymes)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1903573"(negative regulation of response to endoplasmic reticulum stress)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR023257|interpro:IPR035500|mint:Q13133|rcsb pdb:1UHL|rcsb pdb:3IPQ|rcsb pdb:3IPS|rcsb pdb:3IPU|rcsb pdb:5AVI|rcsb pdb:5AVL|rcsb pdb:5HJS|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8866427|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974 refseq:XP_005261712.1|refseq:XP_005261713.1|ensembl:ENSG00000186951(gene)|ensembl:ENST00000262735(transcript)|ensembl:ENST00000402126(transcript)|ensembl:ENST00000407236(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008144"(obsolete drug binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008289"(lipid binding)|go:"GO:0008544"(epidermis development)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010565"(regulation of cellular ketone metabolic process)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010876"(lipid localization)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0010891"(negative regulation of sequestering of triglyceride)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019217"(regulation of fatty acid metabolic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032000"(positive regulation of fatty acid beta-oxidation)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032099"(negative regulation of appetite)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033993"(response to lipid)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0042060"(wound healing)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070166"(enamel mineralization)|go:"GO:0045471"(response to ethanol)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045923"(positive regulation of fatty acid metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046321"(positive regulation of fatty acid oxidation)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051525"(NFAT protein binding)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|rcsb pdb:1I7G|go:"GO:0097371"(MDM2/MDM4 family protein binding)|rcsb pdb:1K7L|rcsb pdb:1KKQ|rcsb pdb:2NPA|rcsb pdb:2P54|rcsb pdb:2REW|rcsb pdb:2ZNN|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1903038"(negative regulation of leukocyte cell-cell adhesion)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1903944"(negative regulation of hepatocyte apoptotic process)|go:"GO:2000191"(regulation of fatty acid transport)|go:"GO:2000272"(negative regulation of signaling receptor activity)|rcsb pdb:3ET1|rcsb pdb:3FEI|rcsb pdb:3G8I|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003074(Peroxisome proliferator-activated receptor)|interpro:IPR003076(Peroxisome proliferator-activated receptor, alpha)|rcsb pdb:3KDT|interpro:IPR013088(Zinc finger, NHR/GATA-type)|rcsb pdb:3KDU|interpro:IPR035500|mint:Q07869|rcsb pdb:3SP6|rcsb pdb:3VI8|rcsb pdb:4BCR|rcsb pdb:4CI4|reactome:R-HSA-1989781|rcsb pdb:5AZT|reactome:R-HSA-2151201|reactome:R-HSA-2426168|rcsb pdb:5HYK|rcsb pdb:6KAX|reactome:R-HSA-381340|rcsb pdb:6KAY|rcsb pdb:6KAZ|reactome:R-HSA-383280|rcsb pdb:6KB0|reactome:R-HSA-400206|rcsb pdb:6KB1|rcsb pdb:6KB2|rcsb pdb:6KB3|rcsb pdb:6KB4|rcsb pdb:6KB5|reactome:R-HSA-400253|reactome:R-HSA-4090294|rcsb pdb:6KB6|reactome:R-HSA-9707564|reactome:R-HSA-9707616|rcsb pdb:6KB7|rcsb pdb:6KB8|rcsb pdb:6KB9|rcsb pdb:6KBA|rcsb pdb:6KXX|rcsb pdb:6KXY|rcsb pdb:6KYP|rcsb pdb:6L36|rcsb pdb:6L37|rcsb pdb:6L38|rcsb pdb:6L96|rcsb pdb:6LX4|rcsb pdb:6LX5|rcsb pdb:6LX6|rcsb pdb:6LX7|rcsb pdb:6LX8|rcsb pdb:6LX9|rcsb pdb:6LXA|rcsb pdb:6LXB|rcsb pdb:6LXC|rcsb pdb:7BPY|rcsb pdb:7BPZ|rcsb pdb:7BQ0|rcsb pdb:7BQ1|rcsb pdb:7BQ2|rcsb pdb:7BQ3|rcsb pdb:7BQ4|rcsb pdb:7C6Q|reactome:R-HSA-1368082|reactome:R-HSA-1368108|refseq:NP_001001928.1|refseq:NP_005027.2|refseq:XP_011528541.1|refseq:XP_011528542.1|refseq:XP_011528543.1|refseq:XP_011528544.1|refseq:XP_011528545.1|refseq:XP_006724332.1|refseq:XP_006724333.1|dip:DIP-241N - - - figure legend:Figure 4, column 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hep_g2)|taxid:9606("Homo sapiens hepatocellular carcinoma (HCC) cells (p53-wt).") - 2019/05/30 2019/06/05 rogid:o1qZ/nvjBXMWVvnnwindfL0HBFE9606 rogid:0ZZ5eL0cNC8OgOvd8spQ5ypBvAo9606 rigid:p6DMTorKHFPjanZVaVfasXWqv70 false - - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0113"(western blot) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0113"(western blot) uniprotkb:Q13133 uniprotkb:Q07869 intact:EBI-781356|uniprotkb:A8K3J9|uniprotkb:Q96H87|uniprotkb:D3DQR1|uniprotkb:Q8IW13|ensembl:ENSP00000387946|ensembl:ENSP00000420656 intact:EBI-78615|uniprotkb:Q16241|uniprotkb:Q92486|uniprotkb:Q92689|uniprotkb:Q9Y3N1|ensembl:ENSP00000262735|ensembl:ENSP00000385246|ensembl:ENSP00000385523|uniprotkb:Q6I9S0|uniprotkb:B0G0X3 psi-mi:nr1h3_human(display_long)|uniprotkb:Liver X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group H member 3(gene name synonym)|uniprotkb:NR1H3(gene name)|psi-mi:NR1H3(display_short)|uniprotkb:LXRA(gene name synonym) psi-mi:ppara_human(display_long)|uniprotkb:PPARA(gene name)|psi-mi:PPARA(display_short)|uniprotkb:NR1C1(gene name synonym)|uniprotkb:PPAR(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group C member 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Balanarasimha et al. (2014) imex:IM-27148|pubmed:24713062 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-21447783|imex:IM-27148-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006718175.1|refseq:XP_006718176.1|refseq:XP_006718178.1|refseq:XP_006718179.1|refseq:NP_001123574.1|refseq:NP_001123573.1|refseq:NP_005684.2|refseq:XP_011518107.1|refseq:XP_005252770.1|refseq:XP_005252762.1|refseq:XP_005252763.1|refseq:XP_005252764.1|refseq:XP_005252766.1|refseq:XP_005252767.1|refseq:XP_016872547.1|ensembl:ENSG00000025434(gene)|ensembl:ENST00000441012(transcript)|ensembl:ENST00000467728(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010867"(positive regulation of triglyceride biosynthetic process)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0015485"(cholesterol binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032369"(negative regulation of lipid transport)|go:"GO:0032376"(positive regulation of cholesterol transport)|go:"GO:0032411"(positive regulation of transporter activity)|go:"GO:0032570"(response to progesterone)|go:"GO:0032810"(sterol response element binding)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043031"(negative regulation of macrophage activation)|go:"GO:0043235"(receptor complex)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0090188"(negative regulation of pancreatic juice secretion)|go:"GO:0090341"(negative regulation of secretion of lysosomal enzymes)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1903573"(negative regulation of response to endoplasmic reticulum stress)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR023257|interpro:IPR035500|mint:Q13133|rcsb pdb:1UHL|rcsb pdb:3IPQ|rcsb pdb:3IPS|rcsb pdb:3IPU|rcsb pdb:5AVI|rcsb pdb:5AVL|rcsb pdb:5HJS|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8866427|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974 refseq:XP_005261712.1|refseq:XP_005261713.1|ensembl:ENSG00000186951(gene)|ensembl:ENST00000262735(transcript)|ensembl:ENST00000402126(transcript)|ensembl:ENST00000407236(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008144"(obsolete drug binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008289"(lipid binding)|go:"GO:0008544"(epidermis development)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010565"(regulation of cellular ketone metabolic process)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010876"(lipid localization)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0010891"(negative regulation of sequestering of triglyceride)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019217"(regulation of fatty acid metabolic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032000"(positive regulation of fatty acid beta-oxidation)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032099"(negative regulation of appetite)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033993"(response to lipid)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0042060"(wound healing)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070166"(enamel mineralization)|go:"GO:0045471"(response to ethanol)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045923"(positive regulation of fatty acid metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046321"(positive regulation of fatty acid oxidation)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051525"(NFAT protein binding)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|rcsb pdb:1I7G|go:"GO:0097371"(MDM2/MDM4 family protein binding)|rcsb pdb:1K7L|rcsb pdb:1KKQ|rcsb pdb:2NPA|rcsb pdb:2P54|rcsb pdb:2REW|rcsb pdb:2ZNN|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1903038"(negative regulation of leukocyte cell-cell adhesion)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1903944"(negative regulation of hepatocyte apoptotic process)|go:"GO:2000191"(regulation of fatty acid transport)|go:"GO:2000272"(negative regulation of signaling receptor activity)|rcsb pdb:3ET1|rcsb pdb:3FEI|rcsb pdb:3G8I|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003074(Peroxisome proliferator-activated receptor)|interpro:IPR003076(Peroxisome proliferator-activated receptor, alpha)|rcsb pdb:3KDT|interpro:IPR013088(Zinc finger, NHR/GATA-type)|rcsb pdb:3KDU|interpro:IPR035500|mint:Q07869|rcsb pdb:3SP6|rcsb pdb:3VI8|rcsb pdb:4BCR|rcsb pdb:4CI4|reactome:R-HSA-1989781|rcsb pdb:5AZT|reactome:R-HSA-2151201|reactome:R-HSA-2426168|rcsb pdb:5HYK|rcsb pdb:6KAX|reactome:R-HSA-381340|rcsb pdb:6KAY|rcsb pdb:6KAZ|reactome:R-HSA-383280|rcsb pdb:6KB0|reactome:R-HSA-400206|rcsb pdb:6KB1|rcsb pdb:6KB2|rcsb pdb:6KB3|rcsb pdb:6KB4|rcsb pdb:6KB5|reactome:R-HSA-400253|reactome:R-HSA-4090294|rcsb pdb:6KB6|reactome:R-HSA-9707564|reactome:R-HSA-9707616|rcsb pdb:6KB7|rcsb pdb:6KB8|rcsb pdb:6KB9|rcsb pdb:6KBA|rcsb pdb:6KXX|rcsb pdb:6KXY|rcsb pdb:6KYP|rcsb pdb:6L36|rcsb pdb:6L37|rcsb pdb:6L38|rcsb pdb:6L96|rcsb pdb:6LX4|rcsb pdb:6LX5|rcsb pdb:6LX6|rcsb pdb:6LX7|rcsb pdb:6LX8|rcsb pdb:6LX9|rcsb pdb:6LXA|rcsb pdb:6LXB|rcsb pdb:6LXC|rcsb pdb:7BPY|rcsb pdb:7BPZ|rcsb pdb:7BQ0|rcsb pdb:7BQ1|rcsb pdb:7BQ2|rcsb pdb:7BQ3|rcsb pdb:7BQ4|rcsb pdb:7C6Q|reactome:R-HSA-1368082|reactome:R-HSA-1368108|refseq:NP_001001928.1|refseq:NP_005027.2|refseq:XP_011528541.1|refseq:XP_011528542.1|refseq:XP_011528543.1|refseq:XP_011528544.1|refseq:XP_011528545.1|refseq:XP_006724332.1|refseq:XP_006724333.1|dip:DIP-241N - - - figure legend:Figure 4, column 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hep_g2)|taxid:9606("Homo sapiens hepatocellular carcinoma (HCC) cells (p53-wt).") - 2019/05/30 2019/06/05 rogid:o1qZ/nvjBXMWVvnnwindfL0HBFE9606 rogid:0ZZ5eL0cNC8OgOvd8spQ5ypBvAo9606 rigid:p6DMTorKHFPjanZVaVfasXWqv70 false - - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0113"(western blot) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0113"(western blot)