#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q12778	uniprotkb:P14921-3	intact:EBI-1108782|uniprotkb:O43523|uniprotkb:Q5VYC7|uniprotkb:Q6NSK6|ensembl:ENSP00000368880	intact:EBI-21403286|ensembl:ENSP00000376436	psi-mi:foxo1_human(display_long)|uniprotkb:FOXO1(gene name)|psi-mi:FOXO1(display_short)|uniprotkb:FKHR(gene name synonym)|uniprotkb:FOXO1A(gene name synonym)|uniprotkb:Forkhead box protein O1A(gene name synonym)|uniprotkb:Forkhead in rhabdomyosarcoma(gene name synonym)	psi-mi:p14921-3(display_long)|uniprotkb:p54(gene name synonym)|uniprotkb:ETS1(gene name)|psi-mi:ETS1(display_short)|uniprotkb:EWSR2(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Choy et al. (2014)	pubmed:24419615|imex:IM-27016	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21403581|imex:IM-27016-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000150907(gene)|ensembl:ENST00000379561(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006473"(protein acetylation)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070166"(enamel mineralization)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070417"(cellular response to cold)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071455"(cellular response to hyperoxia)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097009"(energy homeostasis)|go:"GO:1902617"(response to fluoride)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR030456|interpro:IPR032067|interpro:IPR032068|interpro:IPR036388|interpro:IPR036390|mint:Q12778|rcsb pdb:3CO6|rcsb pdb:3CO7|rcsb pdb:3COA|rcsb pdb:4LG0|rcsb pdb:5DUI|rcsb pdb:6LBI|rcsb pdb:6QVW|rcsb pdb:6QZR|rcsb pdb:6QZS|reactome:R-HSA-198693|reactome:R-HSA-210745|reactome:R-HSA-211163|reactome:R-HSA-5674400|reactome:R-HSA-5687128|reactome:R-HSA-6785807|reactome:R-HSA-9614399|reactome:R-HSA-9614657|reactome:R-HSA-9615017|reactome:R-HSA-9617629|reactome:R-HSA-9617828|refseq:NP_002006.2|dip:DIP-35654N	ensembl:ENSG00000134954(gene)|ensembl:ENST00000392668(transcript)|intact:EBI-913209(isoform-parent)	-	-	isoform-comment:No experimental confirmation available.	figure legend:Figure 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/25	2019/05/15	rogid:oc4WR5KxeJntPcwhZU8zHFyTHCQ9606	rogid:zbR9n7OLsOvxvSAuegx8SpLlw1c9606	-	false	sufficient binding region:143-270(IPR036388)	his tag:n-n|sufficient binding region:331-440(IPR036390)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12778	intact:EBI-21403570	intact:EBI-1108782|uniprotkb:O43523|uniprotkb:Q5VYC7|uniprotkb:Q6NSK6|ensembl:ENSP00000368880	-	psi-mi:foxo1_human(display_long)|uniprotkb:FOXO1(gene name)|psi-mi:FOXO1(display_short)|uniprotkb:FKHR(gene name synonym)|uniprotkb:FOXO1A(gene name synonym)|uniprotkb:Forkhead box protein O1A(gene name synonym)|uniprotkb:Forkhead in rhabdomyosarcoma(gene name synonym)	psi-mi:vecfox_ets(display_short)|psi-mi:EBI-21403570(display_long)	psi-mi:"MI:0071"(molecular sieving)	Choy et al. (2014)	pubmed:24419615|imex:IM-27016	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21403581|imex:IM-27016-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0681"(double stranded deoxyribonucleic acid)	ensembl:ENSG00000150907(gene)|ensembl:ENST00000379561(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006473"(protein acetylation)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070166"(enamel mineralization)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070417"(cellular response to cold)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071455"(cellular response to hyperoxia)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097009"(energy homeostasis)|go:"GO:1902617"(response to fluoride)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR030456|interpro:IPR032067|interpro:IPR032068|interpro:IPR036388|interpro:IPR036390|mint:Q12778|rcsb pdb:3CO6|rcsb pdb:3CO7|rcsb pdb:3COA|rcsb pdb:4LG0|rcsb pdb:5DUI|rcsb pdb:6LBI|rcsb pdb:6QVW|rcsb pdb:6QZR|rcsb pdb:6QZS|reactome:R-HSA-198693|reactome:R-HSA-210745|reactome:R-HSA-211163|reactome:R-HSA-5674400|reactome:R-HSA-5687128|reactome:R-HSA-6785807|reactome:R-HSA-9614399|reactome:R-HSA-9614657|reactome:R-HSA-9615017|reactome:R-HSA-9617629|reactome:R-HSA-9617828|refseq:NP_002006.2|dip:DIP-35654N	-	-	-	-	figure legend:Figure 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/25	2019/05/15	rogid:oc4WR5KxeJntPcwhZU8zHFyTHCQ9606	-	-	false	sufficient binding region:143-270(IPR036388)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-21403570	uniprotkb:P14921-3	-	intact:EBI-21403286|ensembl:ENSP00000376436	psi-mi:vecfox_ets(display_short)|psi-mi:EBI-21403570(display_long)	psi-mi:p14921-3(display_long)|uniprotkb:p54(gene name synonym)|uniprotkb:ETS1(gene name)|psi-mi:ETS1(display_short)|uniprotkb:EWSR2(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Choy et al. (2014)	pubmed:24419615|imex:IM-27016	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21403595|imex:IM-27016-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0681"(double stranded deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000134954(gene)|ensembl:ENST00000392668(transcript)|intact:EBI-913209(isoform-parent)	-	-	isoform-comment:No experimental confirmation available.	figure legend:Figure 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/25	2019/05/15	-	rogid:zbR9n7OLsOvxvSAuegx8SpLlw1c9606	-	false	-	his tag:n-n|sufficient binding region:331-440(IPR036390)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14921-3	uniprotkb:Q12778	intact:EBI-21403286|ensembl:ENSP00000376436	intact:EBI-1108782|uniprotkb:O43523|uniprotkb:Q5VYC7|uniprotkb:Q6NSK6|ensembl:ENSP00000368880	psi-mi:p14921-3(display_long)|uniprotkb:p54(gene name synonym)|uniprotkb:ETS1(gene name)|psi-mi:ETS1(display_short)|uniprotkb:EWSR2(gene name synonym)	psi-mi:foxo1_human(display_long)|uniprotkb:FOXO1(gene name)|psi-mi:FOXO1(display_short)|uniprotkb:FKHR(gene name synonym)|uniprotkb:FOXO1A(gene name synonym)|uniprotkb:Forkhead box protein O1A(gene name synonym)|uniprotkb:Forkhead in rhabdomyosarcoma(gene name synonym)	psi-mi:"MI:0982"(electrophoretic mobility-based method)	Choy et al. (2014)	pubmed:24419615|imex:IM-27016	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21403629|imex:IM-27016-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000134954(gene)|ensembl:ENST00000392668(transcript)|intact:EBI-913209(isoform-parent)	ensembl:ENSG00000150907(gene)|ensembl:ENST00000379561(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006473"(protein acetylation)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070166"(enamel mineralization)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070417"(cellular response to cold)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071455"(cellular response to hyperoxia)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097009"(energy homeostasis)|go:"GO:1902617"(response to fluoride)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR030456|interpro:IPR032067|interpro:IPR032068|interpro:IPR036388|interpro:IPR036390|mint:Q12778|rcsb pdb:3CO6|rcsb pdb:3CO7|rcsb pdb:3COA|rcsb pdb:4LG0|rcsb pdb:5DUI|rcsb pdb:6LBI|rcsb pdb:6QVW|rcsb pdb:6QZR|rcsb pdb:6QZS|reactome:R-HSA-198693|reactome:R-HSA-210745|reactome:R-HSA-211163|reactome:R-HSA-5674400|reactome:R-HSA-5687128|reactome:R-HSA-6785807|reactome:R-HSA-9614399|reactome:R-HSA-9614657|reactome:R-HSA-9615017|reactome:R-HSA-9617629|reactome:R-HSA-9617828|refseq:NP_002006.2|dip:DIP-35654N	-	isoform-comment:No experimental confirmation available.	-	figure legend:Figure 6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/25	2019/09/18	rogid:zbR9n7OLsOvxvSAuegx8SpLlw1c9606	rogid:oc4WR5KxeJntPcwhZU8zHFyTHCQ9606	rigid:E9xG0qFmteAwB4zF+cLt/gj2mUo	false	his tag:n-n|sufficient binding region:331-440(IPR036390)	sufficient binding region:143-270(IPR036388)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)