#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
chebi:"CHEBI:39589"	chebi:"CHEBI:144094"	intact:EBI-21941873	intact:EBI-21941846	psi-mi:"(r)-bicalutamide"(display_short)|psi-mi:"CHEBI:39589"(display_long)|intact:"(-)-bicalutamide"(synonym)|intact:"(R)-(-)bicalutamide"(synonym)|intact:"(R)-Casodex"(synonym)|intact:"(2R)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide"(iupac name)	psi-mi:"(s)-bicalutamide"(display_short)|psi-mi:"CHEBI:144094"(display_long)|intact:"(+)-bicalutamide"(synonym)|intact:"(S)-Casodex"(synonym)|intact:"(2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide"(iupac name)	psi-mi:"MI:0114"(x-ray crystallography)	Mast et al. (2013)	pubmed:23288837|imex:IM-27168	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21923382|imex:IM-27168-1|pdbe:4FIA	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0328"(small molecule)	-	-	-	-	-	figure legend:TABLE 1, FIG. 3|3d-resolution:2.1Å|3d-r-factors:"Rwork: 0.208  Rfree: 0.253"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/07/17	2019/08/20	-	-	-	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:39589"	uniprotkb:Q9Y6A2	intact:EBI-21941873	intact:EBI-10697994|uniprotkb:E7EQG9|uniprotkb:B4DHP8|uniprotkb:Q8N2B0|ensembl:ENSP00000261835	psi-mi:"(r)-bicalutamide"(display_short)|psi-mi:"CHEBI:39589"(display_long)|intact:"(-)-bicalutamide"(synonym)|intact:"(R)-(-)bicalutamide"(synonym)|intact:"(R)-Casodex"(synonym)|intact:"(2R)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide"(iupac name)	psi-mi:cp46a_human(display_long)|uniprotkb:CYP46A1(gene name)|psi-mi:CYP46A1(display_short)|uniprotkb:CYP46(gene name synonym)|uniprotkb:Cytochrome P450 46A1(gene name synonym)|uniprotkb:Cholesterol 24-monooxygenase(gene name synonym)|uniprotkb:Cholesterol 24S-hydroxylase(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Mast et al. (2013)	pubmed:23288837|imex:IM-27168	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21923382|imex:IM-27168-1|pdbe:4FIA	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_006659.1|ensembl:ENSG00000036530(gene)|ensembl:ENST00000261835(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0006707"(cholesterol catabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007399"(nervous system development)|go:"GO:0008395"(steroid hydroxylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0020037"(heme binding)|go:"GO:0030425"(dendrite)|go:"GO:0033781"(cholesterol 24-hydroxylase activity)|go:"GO:0042448"(progesterone metabolic process)|go:"GO:0062184"(testosterone 16-beta-hydroxylase activity)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1903044"(protein localization to membrane raft)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002401(Cytochrome P450, E-class, group I)|interpro:IPR017972|interpro:IPR036396|interpro:IPR039983|rcsb pdb:2Q9F|rcsb pdb:2Q9G|rcsb pdb:3MDM|rcsb pdb:3MDR|rcsb pdb:3MDT|rcsb pdb:3MDV|rcsb pdb:4ENH|rcsb pdb:4FIA|rcsb pdb:4J14|reactome:R-HSA-193775|reactome:R-HSA-211976	-	-	-	figure legend:TABLE 1, FIG. 3|3d-resolution:2.1Å|3d-r-factors:"Rwork: 0.208  Rfree: 0.253"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/07/17	2019/08/20	-	rogid:Oui7tClqfeg1rP3Yxb5f+cRMpZ09606	-	false	-	sufficient binding region:51-500|his tag:c-c	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:39589"	chebi:"CHEBI:26355"	intact:EBI-21941873	intact:EBI-1225103	psi-mi:"(r)-bicalutamide"(display_short)|psi-mi:"CHEBI:39589"(display_long)|intact:"(-)-bicalutamide"(synonym)|intact:"(R)-(-)bicalutamide"(synonym)|intact:"(R)-Casodex"(synonym)|intact:"(2R)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide"(iupac name)	psi-mi:heme b(display_short)|psi-mi:"CHEBI:26355"(display_long)	psi-mi:"MI:0114"(x-ray crystallography)	Mast et al. (2013)	pubmed:23288837|imex:IM-27168	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21923382|imex:IM-27168-1|pdbe:4FIA	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0682"(cofactor)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0328"(small molecule)	-	-	-	-	-	figure legend:TABLE 1, FIG. 3|3d-resolution:2.1Å|3d-r-factors:"Rwork: 0.208  Rfree: 0.253"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/07/17	2019/08/20	-	-	-	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:3090"	uniprotkb:Q9Y6A2	intact:EBI-2877554	intact:EBI-10697994|uniprotkb:E7EQG9|uniprotkb:B4DHP8|uniprotkb:Q8N2B0|ensembl:ENSP00000261835	psi-mi:bicalutamide(display_short)|psi-mi:"CHEBI:3090"(display_long)	psi-mi:cp46a_human(display_long)|uniprotkb:CYP46A1(gene name)|psi-mi:CYP46A1(display_short)|uniprotkb:CYP46(gene name synonym)|uniprotkb:Cytochrome P450 46A1(gene name synonym)|uniprotkb:Cholesterol 24-monooxygenase(gene name synonym)|uniprotkb:Cholesterol 24S-hydroxylase(gene name synonym)	psi-mi:"MI:0966"(ultraviolet-visible spectroscopy)	Mast et al. (2013)	pubmed:23288837|imex:IM-27168	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21923401|imex:IM-27168-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_006659.1|ensembl:ENSG00000036530(gene)|ensembl:ENST00000261835(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0006707"(cholesterol catabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007399"(nervous system development)|go:"GO:0008395"(steroid hydroxylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0020037"(heme binding)|go:"GO:0030425"(dendrite)|go:"GO:0033781"(cholesterol 24-hydroxylase activity)|go:"GO:0042448"(progesterone metabolic process)|go:"GO:0062184"(testosterone 16-beta-hydroxylase activity)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1903044"(protein localization to membrane raft)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002401(Cytochrome P450, E-class, group I)|interpro:IPR017972|interpro:IPR036396|interpro:IPR039983|rcsb pdb:2Q9F|rcsb pdb:2Q9G|rcsb pdb:3MDM|rcsb pdb:3MDR|rcsb pdb:3MDT|rcsb pdb:3MDV|rcsb pdb:4ENH|rcsb pdb:4FIA|rcsb pdb:4J14|reactome:R-HSA-193775|reactome:R-HSA-211976	-	-	-	figure legend:FIGURES 1A, 1C, 8, 9|comment:Changes elicited by racBIC in CYP46A1-imidazole adduct were identical to those in substrate-free CYP46A1.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.4x10^-6 ~0.2(molar)	2019/07/17	2019/07/29	-	rogid:Oui7tClqfeg1rP3Yxb5f+cRMpZ09606	-	false	-	mutation disrupting interaction strength:226-226|mutation with no effect:81-81|mutation decreasing interaction strength:82-82|mutation increasing interaction strength:82-82|mutation decreasing interaction strength:110-110|mutation increasing interaction strength:226-226|mutation decreasing interaction strength:306-306|mutation increasing interaction strength:368-368|mutation decreasing interaction strength:474-474	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:144094"	uniprotkb:Q9Y6A2	intact:EBI-21941846	intact:EBI-10697994|uniprotkb:E7EQG9|uniprotkb:B4DHP8|uniprotkb:Q8N2B0|ensembl:ENSP00000261835	psi-mi:"(s)-bicalutamide"(display_short)|psi-mi:"CHEBI:144094"(display_long)|intact:"(+)-bicalutamide"(synonym)|intact:"(S)-Casodex"(synonym)|intact:"(2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide"(iupac name)	psi-mi:cp46a_human(display_long)|uniprotkb:CYP46A1(gene name)|psi-mi:CYP46A1(display_short)|uniprotkb:CYP46(gene name synonym)|uniprotkb:Cytochrome P450 46A1(gene name synonym)|uniprotkb:Cholesterol 24-monooxygenase(gene name synonym)|uniprotkb:Cholesterol 24S-hydroxylase(gene name synonym)	psi-mi:"MI:0966"(ultraviolet-visible spectroscopy)	Mast et al. (2013)	pubmed:23288837|imex:IM-27168	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21941819|imex:IM-27168-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_006659.1|ensembl:ENSG00000036530(gene)|ensembl:ENST00000261835(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0006707"(cholesterol catabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007399"(nervous system development)|go:"GO:0008395"(steroid hydroxylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0020037"(heme binding)|go:"GO:0030425"(dendrite)|go:"GO:0033781"(cholesterol 24-hydroxylase activity)|go:"GO:0042448"(progesterone metabolic process)|go:"GO:0062184"(testosterone 16-beta-hydroxylase activity)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1903044"(protein localization to membrane raft)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002401(Cytochrome P450, E-class, group I)|interpro:IPR017972|interpro:IPR036396|interpro:IPR039983|rcsb pdb:2Q9F|rcsb pdb:2Q9G|rcsb pdb:3MDM|rcsb pdb:3MDR|rcsb pdb:3MDT|rcsb pdb:3MDV|rcsb pdb:4ENH|rcsb pdb:4FIA|rcsb pdb:4J14|reactome:R-HSA-193775|reactome:R-HSA-211976	-	-	-	figure legend:FIGURES 1D, 8, 9|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.8x10^-6 ~0.2(molar)	2019/07/17	2019/07/29	-	rogid:Oui7tClqfeg1rP3Yxb5f+cRMpZ09606	-	false	-	mutation increasing interaction strength:82-82|mutation increasing interaction strength:81-81|mutation increasing interaction strength:82-82|mutation increasing interaction strength:110-110|mutation increasing interaction strength:226-226|mutation increasing interaction strength:226-226|mutation decreasing interaction strength:306-306|mutation increasing interaction strength:368-368|mutation increasing interaction strength:474-474	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:39589"	uniprotkb:Q9Y6A2	intact:EBI-21941873	intact:EBI-10697994|uniprotkb:E7EQG9|uniprotkb:B4DHP8|uniprotkb:Q8N2B0|ensembl:ENSP00000261835	psi-mi:"(r)-bicalutamide"(display_short)|psi-mi:"CHEBI:39589"(display_long)|intact:"(-)-bicalutamide"(synonym)|intact:"(R)-(-)bicalutamide"(synonym)|intact:"(R)-Casodex"(synonym)|intact:"(2R)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide"(iupac name)	psi-mi:cp46a_human(display_long)|uniprotkb:CYP46A1(gene name)|psi-mi:CYP46A1(display_short)|uniprotkb:CYP46(gene name synonym)|uniprotkb:Cytochrome P450 46A1(gene name synonym)|uniprotkb:Cholesterol 24-monooxygenase(gene name synonym)|uniprotkb:Cholesterol 24S-hydroxylase(gene name synonym)	psi-mi:"MI:0966"(ultraviolet-visible spectroscopy)	Mast et al. (2013)	pubmed:23288837|imex:IM-27168	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21941856|imex:IM-27168-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_006659.1|ensembl:ENSG00000036530(gene)|ensembl:ENST00000261835(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0006707"(cholesterol catabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007399"(nervous system development)|go:"GO:0008395"(steroid hydroxylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0020037"(heme binding)|go:"GO:0030425"(dendrite)|go:"GO:0033781"(cholesterol 24-hydroxylase activity)|go:"GO:0042448"(progesterone metabolic process)|go:"GO:0062184"(testosterone 16-beta-hydroxylase activity)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1903044"(protein localization to membrane raft)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002401(Cytochrome P450, E-class, group I)|interpro:IPR017972|interpro:IPR036396|interpro:IPR039983|rcsb pdb:2Q9F|rcsb pdb:2Q9G|rcsb pdb:3MDM|rcsb pdb:3MDR|rcsb pdb:3MDT|rcsb pdb:3MDV|rcsb pdb:4ENH|rcsb pdb:4FIA|rcsb pdb:4J14|reactome:R-HSA-193775|reactome:R-HSA-211976	-	-	-	figure legend:FIGURES 1E, 8, 9|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:2.9x10^-6 ~0.4(molar)	2019/07/17	2019/07/29	-	rogid:Oui7tClqfeg1rP3Yxb5f+cRMpZ09606	-	false	-	mutation increasing interaction strength:226-226|mutation decreasing interaction strength:226-226|mutation disrupting interaction strength:306-306|mutation increasing interaction strength:368-368|mutation decreasing interaction strength:474-474|mutation decreasing interaction strength:82-82|mutation increasing interaction strength:81-81|mutation decreasing interaction strength:82-82|mutation increasing interaction strength:110-110	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:34310"	uniprotkb:Q9Y6A2	intact:EBI-21941965	intact:EBI-10697994|uniprotkb:E7EQG9|uniprotkb:B4DHP8|uniprotkb:Q8N2B0|ensembl:ENSP00000261835	psi-mi:"(24s)-24-hydroxycholesterol"(display_short)|psi-mi:"CHEBI:34310"(display_long)|intact:"(24S)-24-Hydroxycholesterol"(synonym)|intact:"(24S)-hydroxycholesterol"(synonym)|intact:24-Hydroxycholesterol(synonym)|intact:24S-hydroxy-cholesterol(synonym)|intact:Cerebrosterol(synonym)|intact:cholest-5-en-3beta,24S-diol(synonym)|intact:Cholest-5-ene-3,24-diol(synonym)|intact:"(24S)-cholest-5-ene-3beta,24-diol"(iupac name)	psi-mi:cp46a_human(display_long)|uniprotkb:CYP46A1(gene name)|psi-mi:CYP46A1(display_short)|uniprotkb:CYP46(gene name synonym)|uniprotkb:Cytochrome P450 46A1(gene name synonym)|uniprotkb:Cholesterol 24-monooxygenase(gene name synonym)|uniprotkb:Cholesterol 24S-hydroxylase(gene name synonym)	psi-mi:"MI:0966"(ultraviolet-visible spectroscopy)	Mast et al. (2013)	pubmed:23288837|imex:IM-27168	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0414"(enzymatic reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21941927|imex:IM-27168-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_006659.1|ensembl:ENSG00000036530(gene)|ensembl:ENST00000261835(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0006707"(cholesterol catabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007399"(nervous system development)|go:"GO:0008395"(steroid hydroxylase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0020037"(heme binding)|go:"GO:0030425"(dendrite)|go:"GO:0033781"(cholesterol 24-hydroxylase activity)|go:"GO:0042448"(progesterone metabolic process)|go:"GO:0062184"(testosterone 16-beta-hydroxylase activity)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1903044"(protein localization to membrane raft)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002401(Cytochrome P450, E-class, group I)|interpro:IPR017972|interpro:IPR036396|interpro:IPR039983|rcsb pdb:2Q9F|rcsb pdb:2Q9G|rcsb pdb:3MDM|rcsb pdb:3MDR|rcsb pdb:3MDT|rcsb pdb:3MDV|rcsb pdb:4ENH|rcsb pdb:4FIA|rcsb pdb:4J14|reactome:R-HSA-193775|reactome:R-HSA-211976	-	-	-	figure legend:FIGURE 1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:0.2x10^-6(molar)	2019/07/17	2019/08/20	-	rogid:Oui7tClqfeg1rP3Yxb5f+cRMpZ09606	-	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)