#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P61073	uniprotkb:P49682	intact:EBI-489411|uniprotkb:Q53S69|uniprotkb:O60835|uniprotkb:P30991|uniprotkb:P56438|uniprotkb:Q9UKN2|uniprotkb:B2R5N0|uniprotkb:Q9BXA0|ensembl:ENSP00000241393	intact:EBI-12836456|ensembl:ENSP00000362797|uniprotkb:B2R982|uniprotkb:O15185|uniprotkb:Q7Z710|uniprotkb:Q9P2T4|uniprotkb:Q9P2T5	psi-mi:cxcr4_human(display_long)|uniprotkb:Stromal cell-derived factor 1 receptor(gene name synonym)|uniprotkb:Fusin(gene name synonym)|uniprotkb:Leukocyte-derived seven transmembrane domain receptor(gene name synonym)|uniprotkb:LCR1(gene name synonym)|uniprotkb:FB22(gene name synonym)|uniprotkb:NPYRL(gene name synonym)|uniprotkb:HM89(gene name synonym)|uniprotkb:CXCR4(gene name)|psi-mi:CXCR4(display_short)|uniprotkb:Lipopolysaccharide-associated protein 3(gene name synonym)	psi-mi:cxcr3_human(display_long)|uniprotkb:CXCR3(gene name)|psi-mi:CXCR3(display_short)|uniprotkb:CKR-L2(gene name synonym)|uniprotkb:G protein-coupled receptor 9(gene name synonym)|uniprotkb:GPR9(gene name synonym)|uniprotkb:Interferon-inducible protein 10 receptor(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Watts et al. (2013)	imex:IM-26956|pubmed:23170857	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21396987|imex:IM-26956-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008540.1|refseq:NP_003458.1|refseq:NP_001334985.1|refseq:NP_001334988.1|refseq:NP_001334989.1|dip:DIP-34773N|dip:DIP-46290N|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007420"(brain development)|go:"GO:0008038"(neuron recognition)|go:"GO:0009615"(response to virus)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0022029"(telencephalon cell migration)|go:"GO:0030054"(cell junction)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035470"(positive regulation of vascular wound healing)|go:"GO:0035690"|go:"GO:0038147"(C-X-C motif chemokine 12 receptor activity)|go:"GO:0038160"(CXCL12-activated CXCR4 signaling pathway)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR022726|mint:P61073|rcsb pdb:2K03|rcsb pdb:2K04|rcsb pdb:2K05|rcsb pdb:2N55|rcsb pdb:3ODU|rcsb pdb:3OE0|rcsb pdb:3OE6|rcsb pdb:3OE8|rcsb pdb:3OE9|rcsb pdb:4RWS|reactome:R-HSA-173107|reactome:R-HSA-376176|reactome:R-HSA-380108|reactome:R-HSA-418594|go:"GO:0043217"(myelin maintenance)|go:"GO:0043278"(response to morphine)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050792"(regulation of viral process)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1905322"(positive regulation of mesenchymal stem cell migration)|go:"GO:1990478"(response to ultrasound)|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR001277(C-X-C chemokine receptor, type 4)|ensembl:ENSG00000121966(gene)|ensembl:ENST00000241393(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001764"(neuron migration)|go:"GO:0002064"(epithelial cell development)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0003779"(actin binding)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)	go:"GO:0038023"(signaling receptor activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0060326"(cell chemotaxis)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR004070(C-X-C chemokine receptor, type 3)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-380108|reactome:R-HSA-418594|go:"GO:0030155"(regulation of cell adhesion)|ensembl:ENSG00000186810(gene)|ensembl:ENST00000373693(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002685"(regulation of leukocyte migration)|go:"GO:0004950"(chemokine receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010818"(T cell chemotaxis)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019956"(chemokine binding)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0019958"(C-X-C chemokine binding)|refseq:NP_001136269.1|refseq:NP_001495.1|refseq:XP_016884924.1|dip:DIP-5891N	-	-	-	figure legend:Figure 1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/04/30	2019/05/02	rogid:/DC0/+M1YsFLLfsDimppXSS/vpQ9606	rogid:P9WxnLkV6IH50a6feWDd6KsoNlA9606	rigid:Cs898bCY32xzEyBVbVn83zzzKz0	false	flag tag:n-n	ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P61073	uniprotkb:P49682	intact:EBI-489411|uniprotkb:Q53S69|uniprotkb:O60835|uniprotkb:P30991|uniprotkb:P56438|uniprotkb:Q9UKN2|uniprotkb:B2R5N0|uniprotkb:Q9BXA0|ensembl:ENSP00000241393	intact:EBI-12836456|ensembl:ENSP00000362797|uniprotkb:B2R982|uniprotkb:O15185|uniprotkb:Q7Z710|uniprotkb:Q9P2T4|uniprotkb:Q9P2T5	psi-mi:cxcr4_human(display_long)|uniprotkb:Stromal cell-derived factor 1 receptor(gene name synonym)|uniprotkb:Fusin(gene name synonym)|uniprotkb:Leukocyte-derived seven transmembrane domain receptor(gene name synonym)|uniprotkb:LCR1(gene name synonym)|uniprotkb:FB22(gene name synonym)|uniprotkb:NPYRL(gene name synonym)|uniprotkb:HM89(gene name synonym)|uniprotkb:CXCR4(gene name)|psi-mi:CXCR4(display_short)|uniprotkb:Lipopolysaccharide-associated protein 3(gene name synonym)	psi-mi:cxcr3_human(display_long)|uniprotkb:CXCR3(gene name)|psi-mi:CXCR3(display_short)|uniprotkb:CKR-L2(gene name synonym)|uniprotkb:G protein-coupled receptor 9(gene name synonym)|uniprotkb:GPR9(gene name synonym)|uniprotkb:Interferon-inducible protein 10 receptor(gene name synonym)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Watts et al. (2013)	imex:IM-26956|pubmed:23170857	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21397004|imex:IM-26956-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008540.1|refseq:NP_003458.1|refseq:NP_001334985.1|refseq:NP_001334988.1|refseq:NP_001334989.1|dip:DIP-34773N|dip:DIP-46290N|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007420"(brain development)|go:"GO:0008038"(neuron recognition)|go:"GO:0009615"(response to virus)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0022029"(telencephalon cell migration)|go:"GO:0030054"(cell junction)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035470"(positive regulation of vascular wound healing)|go:"GO:0035690"|go:"GO:0038147"(C-X-C motif chemokine 12 receptor activity)|go:"GO:0038160"(CXCL12-activated CXCR4 signaling pathway)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR022726|mint:P61073|rcsb pdb:2K03|rcsb pdb:2K04|rcsb pdb:2K05|rcsb pdb:2N55|rcsb pdb:3ODU|rcsb pdb:3OE0|rcsb pdb:3OE6|rcsb pdb:3OE8|rcsb pdb:3OE9|rcsb pdb:4RWS|reactome:R-HSA-173107|reactome:R-HSA-376176|reactome:R-HSA-380108|reactome:R-HSA-418594|go:"GO:0043217"(myelin maintenance)|go:"GO:0043278"(response to morphine)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050792"(regulation of viral process)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1905322"(positive regulation of mesenchymal stem cell migration)|go:"GO:1990478"(response to ultrasound)|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR001277(C-X-C chemokine receptor, type 4)|ensembl:ENSG00000121966(gene)|ensembl:ENST00000241393(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001764"(neuron migration)|go:"GO:0002064"(epithelial cell development)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0003779"(actin binding)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)	go:"GO:0038023"(signaling receptor activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0060326"(cell chemotaxis)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR004070(C-X-C chemokine receptor, type 3)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-380108|reactome:R-HSA-418594|go:"GO:0030155"(regulation of cell adhesion)|ensembl:ENSG00000186810(gene)|ensembl:ENST00000373693(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002685"(regulation of leukocyte migration)|go:"GO:0004950"(chemokine receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010818"(T cell chemotaxis)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019956"(chemokine binding)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0019958"(C-X-C chemokine binding)|refseq:NP_001136269.1|refseq:NP_001495.1|refseq:XP_016884924.1|dip:DIP-5891N	-	-	-	figure legend:Figure 1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/04/30	2019/05/02	rogid:/DC0/+M1YsFLLfsDimppXSS/vpQ9606	rogid:P9WxnLkV6IH50a6feWDd6KsoNlA9606	rigid:Cs898bCY32xzEyBVbVn83zzzKz0	false	flag tag:n-n	ha tag:n-n	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:P49682	uniprotkb:P49682	intact:EBI-12836456|ensembl:ENSP00000362797|uniprotkb:B2R982|uniprotkb:O15185|uniprotkb:Q7Z710|uniprotkb:Q9P2T4|uniprotkb:Q9P2T5	intact:EBI-12836456|ensembl:ENSP00000362797|uniprotkb:B2R982|uniprotkb:O15185|uniprotkb:Q7Z710|uniprotkb:Q9P2T4|uniprotkb:Q9P2T5	psi-mi:cxcr3_human(display_long)|uniprotkb:CXCR3(gene name)|psi-mi:CXCR3(display_short)|uniprotkb:CKR-L2(gene name synonym)|uniprotkb:G protein-coupled receptor 9(gene name synonym)|uniprotkb:GPR9(gene name synonym)|uniprotkb:Interferon-inducible protein 10 receptor(gene name synonym)	psi-mi:cxcr3_human(display_long)|uniprotkb:CXCR3(gene name)|psi-mi:CXCR3(display_short)|uniprotkb:CKR-L2(gene name synonym)|uniprotkb:G protein-coupled receptor 9(gene name synonym)|uniprotkb:GPR9(gene name synonym)|uniprotkb:Interferon-inducible protein 10 receptor(gene name synonym)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Watts et al. (2013)	imex:IM-26956|pubmed:23170857	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21397033|imex:IM-26956-18	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0038023"(signaling receptor activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0060326"(cell chemotaxis)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR004070(C-X-C chemokine receptor, type 3)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-380108|reactome:R-HSA-418594|go:"GO:0030155"(regulation of cell adhesion)|ensembl:ENSG00000186810(gene)|ensembl:ENST00000373693(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002685"(regulation of leukocyte migration)|go:"GO:0004950"(chemokine receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010818"(T cell chemotaxis)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019956"(chemokine binding)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0019958"(C-X-C chemokine binding)|refseq:NP_001136269.1|refseq:NP_001495.1|refseq:XP_016884924.1|dip:DIP-5891N	go:"GO:0038023"(signaling receptor activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0060326"(cell chemotaxis)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR004070(C-X-C chemokine receptor, type 3)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-380108|reactome:R-HSA-418594|go:"GO:0030155"(regulation of cell adhesion)|ensembl:ENSG00000186810(gene)|ensembl:ENST00000373693(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002685"(regulation of leukocyte migration)|go:"GO:0004950"(chemokine receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010818"(T cell chemotaxis)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019956"(chemokine binding)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0019958"(C-X-C chemokine binding)|refseq:NP_001136269.1|refseq:NP_001495.1|refseq:XP_016884924.1|dip:DIP-5891N	-	-	-	figure legend:Figure 2-2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/04/30	2019/05/02	rogid:P9WxnLkV6IH50a6feWDd6KsoNlA9606	rogid:P9WxnLkV6IH50a6feWDd6KsoNlA9606	rigid:jeB/eTdYkWzl1NOgaTMlyvAiIGU	false	cyan fluorescent protein tag:c-c	venus fluorescent protein tag:c-c	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P49682	uniprotkb:P61073	intact:EBI-12836456|ensembl:ENSP00000362797|uniprotkb:B2R982|uniprotkb:O15185|uniprotkb:Q7Z710|uniprotkb:Q9P2T4|uniprotkb:Q9P2T5	intact:EBI-489411|uniprotkb:Q53S69|uniprotkb:O60835|uniprotkb:P30991|uniprotkb:P56438|uniprotkb:Q9UKN2|uniprotkb:B2R5N0|uniprotkb:Q9BXA0|ensembl:ENSP00000241393	psi-mi:cxcr3_human(display_long)|uniprotkb:CXCR3(gene name)|psi-mi:CXCR3(display_short)|uniprotkb:CKR-L2(gene name synonym)|uniprotkb:G protein-coupled receptor 9(gene name synonym)|uniprotkb:GPR9(gene name synonym)|uniprotkb:Interferon-inducible protein 10 receptor(gene name synonym)	psi-mi:cxcr4_human(display_long)|uniprotkb:Stromal cell-derived factor 1 receptor(gene name synonym)|uniprotkb:Fusin(gene name synonym)|uniprotkb:Leukocyte-derived seven transmembrane domain receptor(gene name synonym)|uniprotkb:LCR1(gene name synonym)|uniprotkb:FB22(gene name synonym)|uniprotkb:NPYRL(gene name synonym)|uniprotkb:HM89(gene name synonym)|uniprotkb:CXCR4(gene name)|psi-mi:CXCR4(display_short)|uniprotkb:Lipopolysaccharide-associated protein 3(gene name synonym)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Watts et al. (2013)	imex:IM-26956|pubmed:23170857	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21405409|imex:IM-26956-20	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0038023"(signaling receptor activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0060326"(cell chemotaxis)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR004070(C-X-C chemokine receptor, type 3)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-380108|reactome:R-HSA-418594|go:"GO:0030155"(regulation of cell adhesion)|ensembl:ENSG00000186810(gene)|ensembl:ENST00000373693(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002685"(regulation of leukocyte migration)|go:"GO:0004950"(chemokine receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010818"(T cell chemotaxis)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019956"(chemokine binding)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0019958"(C-X-C chemokine binding)|refseq:NP_001136269.1|refseq:NP_001495.1|refseq:XP_016884924.1|dip:DIP-5891N	refseq:NP_001008540.1|refseq:NP_003458.1|refseq:NP_001334985.1|refseq:NP_001334988.1|refseq:NP_001334989.1|dip:DIP-34773N|dip:DIP-46290N|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007420"(brain development)|go:"GO:0008038"(neuron recognition)|go:"GO:0009615"(response to virus)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0022029"(telencephalon cell migration)|go:"GO:0030054"(cell junction)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035470"(positive regulation of vascular wound healing)|go:"GO:0035690"|go:"GO:0038147"(C-X-C motif chemokine 12 receptor activity)|go:"GO:0038160"(CXCL12-activated CXCR4 signaling pathway)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR022726|mint:P61073|rcsb pdb:2K03|rcsb pdb:2K04|rcsb pdb:2K05|rcsb pdb:2N55|rcsb pdb:3ODU|rcsb pdb:3OE0|rcsb pdb:3OE6|rcsb pdb:3OE8|rcsb pdb:3OE9|rcsb pdb:4RWS|reactome:R-HSA-173107|reactome:R-HSA-376176|reactome:R-HSA-380108|reactome:R-HSA-418594|go:"GO:0043217"(myelin maintenance)|go:"GO:0043278"(response to morphine)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050792"(regulation of viral process)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1905322"(positive regulation of mesenchymal stem cell migration)|go:"GO:1990478"(response to ultrasound)|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR001277(C-X-C chemokine receptor, type 4)|ensembl:ENSG00000121966(gene)|ensembl:ENST00000241393(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001764"(neuron migration)|go:"GO:0002064"(epithelial cell development)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0003779"(actin binding)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)	-	-	-	figure legend:Figure 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/04/30	2019/05/22	rogid:P9WxnLkV6IH50a6feWDd6KsoNlA9606	rogid:/DC0/+M1YsFLLfsDimppXSS/vpQ9606	rigid:Cs898bCY32xzEyBVbVn83zzzKz0	false	cyan fluorescent protein tag:c-c	venus fluorescent protein tag:c-c	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P61073	uniprotkb:P49682	intact:EBI-489411|uniprotkb:Q53S69|uniprotkb:O60835|uniprotkb:P30991|uniprotkb:P56438|uniprotkb:Q9UKN2|uniprotkb:B2R5N0|uniprotkb:Q9BXA0|ensembl:ENSP00000241393	intact:EBI-12836456|ensembl:ENSP00000362797|uniprotkb:B2R982|uniprotkb:O15185|uniprotkb:Q7Z710|uniprotkb:Q9P2T4|uniprotkb:Q9P2T5	psi-mi:cxcr4_human(display_long)|uniprotkb:Stromal cell-derived factor 1 receptor(gene name synonym)|uniprotkb:Fusin(gene name synonym)|uniprotkb:Leukocyte-derived seven transmembrane domain receptor(gene name synonym)|uniprotkb:LCR1(gene name synonym)|uniprotkb:FB22(gene name synonym)|uniprotkb:NPYRL(gene name synonym)|uniprotkb:HM89(gene name synonym)|uniprotkb:CXCR4(gene name)|psi-mi:CXCR4(display_short)|uniprotkb:Lipopolysaccharide-associated protein 3(gene name synonym)	psi-mi:cxcr3_human(display_long)|uniprotkb:CXCR3(gene name)|psi-mi:CXCR3(display_short)|uniprotkb:CKR-L2(gene name synonym)|uniprotkb:G protein-coupled receptor 9(gene name synonym)|uniprotkb:GPR9(gene name synonym)|uniprotkb:Interferon-inducible protein 10 receptor(gene name synonym)	psi-mi:"MI:0012"(bioluminescence resonance energy transfer)	Watts et al. (2013)	imex:IM-26956|pubmed:23170857	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21397024|imex:IM-26956-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008540.1|refseq:NP_003458.1|refseq:NP_001334985.1|refseq:NP_001334988.1|refseq:NP_001334989.1|dip:DIP-34773N|dip:DIP-46290N|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007420"(brain development)|go:"GO:0008038"(neuron recognition)|go:"GO:0009615"(response to virus)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0022029"(telencephalon cell migration)|go:"GO:0030054"(cell junction)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035470"(positive regulation of vascular wound healing)|go:"GO:0035690"|go:"GO:0038147"(C-X-C motif chemokine 12 receptor activity)|go:"GO:0038160"(CXCL12-activated CXCR4 signaling pathway)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR022726|mint:P61073|rcsb pdb:2K03|rcsb pdb:2K04|rcsb pdb:2K05|rcsb pdb:2N55|rcsb pdb:3ODU|rcsb pdb:3OE0|rcsb pdb:3OE6|rcsb pdb:3OE8|rcsb pdb:3OE9|rcsb pdb:4RWS|reactome:R-HSA-173107|reactome:R-HSA-376176|reactome:R-HSA-380108|reactome:R-HSA-418594|go:"GO:0043217"(myelin maintenance)|go:"GO:0043278"(response to morphine)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050792"(regulation of viral process)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1905322"(positive regulation of mesenchymal stem cell migration)|go:"GO:1990478"(response to ultrasound)|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR001277(C-X-C chemokine receptor, type 4)|ensembl:ENSG00000121966(gene)|ensembl:ENST00000241393(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001764"(neuron migration)|go:"GO:0002064"(epithelial cell development)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0003779"(actin binding)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)	go:"GO:0038023"(signaling receptor activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0060326"(cell chemotaxis)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR004070(C-X-C chemokine receptor, type 3)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-380108|reactome:R-HSA-418594|go:"GO:0030155"(regulation of cell adhesion)|ensembl:ENSG00000186810(gene)|ensembl:ENST00000373693(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002685"(regulation of leukocyte migration)|go:"GO:0004950"(chemokine receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010818"(T cell chemotaxis)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019956"(chemokine binding)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0019958"(C-X-C chemokine binding)|refseq:NP_001136269.1|refseq:NP_001495.1|refseq:XP_016884924.1|dip:DIP-5891N	-	-	-	figure legend:Figure 3, Table 1-2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/04/30	2019/05/22	rogid:/DC0/+M1YsFLLfsDimppXSS/vpQ9606	rogid:P9WxnLkV6IH50a6feWDd6KsoNlA9606	rigid:Cs898bCY32xzEyBVbVn83zzzKz0	false	renilla luciferase protein tag:c-c	enhanced yellow fluorescent protein tag:c-c	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:P61073	uniprotkb:P61073	intact:EBI-489411|uniprotkb:Q53S69|uniprotkb:O60835|uniprotkb:P30991|uniprotkb:P56438|uniprotkb:Q9UKN2|uniprotkb:B2R5N0|uniprotkb:Q9BXA0|ensembl:ENSP00000241393	intact:EBI-489411|uniprotkb:Q53S69|uniprotkb:O60835|uniprotkb:P30991|uniprotkb:P56438|uniprotkb:Q9UKN2|uniprotkb:B2R5N0|uniprotkb:Q9BXA0|ensembl:ENSP00000241393	psi-mi:cxcr4_human(display_long)|uniprotkb:Stromal cell-derived factor 1 receptor(gene name synonym)|uniprotkb:Fusin(gene name synonym)|uniprotkb:Leukocyte-derived seven transmembrane domain receptor(gene name synonym)|uniprotkb:LCR1(gene name synonym)|uniprotkb:FB22(gene name synonym)|uniprotkb:NPYRL(gene name synonym)|uniprotkb:HM89(gene name synonym)|uniprotkb:CXCR4(gene name)|psi-mi:CXCR4(display_short)|uniprotkb:Lipopolysaccharide-associated protein 3(gene name synonym)	psi-mi:cxcr4_human(display_long)|uniprotkb:Stromal cell-derived factor 1 receptor(gene name synonym)|uniprotkb:Fusin(gene name synonym)|uniprotkb:Leukocyte-derived seven transmembrane domain receptor(gene name synonym)|uniprotkb:LCR1(gene name synonym)|uniprotkb:FB22(gene name synonym)|uniprotkb:NPYRL(gene name synonym)|uniprotkb:HM89(gene name synonym)|uniprotkb:CXCR4(gene name)|psi-mi:CXCR4(display_short)|uniprotkb:Lipopolysaccharide-associated protein 3(gene name synonym)	psi-mi:"MI:0012"(bioluminescence resonance energy transfer)	Watts et al. (2013)	imex:IM-26956|pubmed:23170857	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21397066|imex:IM-26956-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008540.1|refseq:NP_003458.1|refseq:NP_001334985.1|refseq:NP_001334988.1|refseq:NP_001334989.1|dip:DIP-34773N|dip:DIP-46290N|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007420"(brain development)|go:"GO:0008038"(neuron recognition)|go:"GO:0009615"(response to virus)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0022029"(telencephalon cell migration)|go:"GO:0030054"(cell junction)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035470"(positive regulation of vascular wound healing)|go:"GO:0035690"|go:"GO:0038147"(C-X-C motif chemokine 12 receptor activity)|go:"GO:0038160"(CXCL12-activated CXCR4 signaling pathway)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR022726|mint:P61073|rcsb pdb:2K03|rcsb pdb:2K04|rcsb pdb:2K05|rcsb pdb:2N55|rcsb pdb:3ODU|rcsb pdb:3OE0|rcsb pdb:3OE6|rcsb pdb:3OE8|rcsb pdb:3OE9|rcsb pdb:4RWS|reactome:R-HSA-173107|reactome:R-HSA-376176|reactome:R-HSA-380108|reactome:R-HSA-418594|go:"GO:0043217"(myelin maintenance)|go:"GO:0043278"(response to morphine)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050792"(regulation of viral process)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1905322"(positive regulation of mesenchymal stem cell migration)|go:"GO:1990478"(response to ultrasound)|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR001277(C-X-C chemokine receptor, type 4)|ensembl:ENSG00000121966(gene)|ensembl:ENST00000241393(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001764"(neuron migration)|go:"GO:0002064"(epithelial cell development)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0003779"(actin binding)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)	refseq:NP_001008540.1|refseq:NP_003458.1|refseq:NP_001334985.1|refseq:NP_001334988.1|refseq:NP_001334989.1|dip:DIP-34773N|dip:DIP-46290N|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007420"(brain development)|go:"GO:0008038"(neuron recognition)|go:"GO:0009615"(response to virus)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0022029"(telencephalon cell migration)|go:"GO:0030054"(cell junction)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035470"(positive regulation of vascular wound healing)|go:"GO:0035690"|go:"GO:0038147"(C-X-C motif chemokine 12 receptor activity)|go:"GO:0038160"(CXCL12-activated CXCR4 signaling pathway)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR022726|mint:P61073|rcsb pdb:2K03|rcsb pdb:2K04|rcsb pdb:2K05|rcsb pdb:2N55|rcsb pdb:3ODU|rcsb pdb:3OE0|rcsb pdb:3OE6|rcsb pdb:3OE8|rcsb pdb:3OE9|rcsb pdb:4RWS|reactome:R-HSA-173107|reactome:R-HSA-376176|reactome:R-HSA-380108|reactome:R-HSA-418594|go:"GO:0043217"(myelin maintenance)|go:"GO:0043278"(response to morphine)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050792"(regulation of viral process)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1905322"(positive regulation of mesenchymal stem cell migration)|go:"GO:1990478"(response to ultrasound)|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR001277(C-X-C chemokine receptor, type 4)|ensembl:ENSG00000121966(gene)|ensembl:ENST00000241393(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001764"(neuron migration)|go:"GO:0002064"(epithelial cell development)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0003779"(actin binding)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)	-	-	-	figure legend:Figure 3, Table 1-1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/04/30	2019/05/22	rogid:/DC0/+M1YsFLLfsDimppXSS/vpQ9606	rogid:/DC0/+M1YsFLLfsDimppXSS/vpQ9606	rigid:hhJ9t4WNPkRthtmHETsqvI5YaO0	false	renilla luciferase protein tag:c-c	enhanced yellow fluorescent protein tag:c-c	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:P49682	uniprotkb:P49682	intact:EBI-12836456|ensembl:ENSP00000362797|uniprotkb:B2R982|uniprotkb:O15185|uniprotkb:Q7Z710|uniprotkb:Q9P2T4|uniprotkb:Q9P2T5	intact:EBI-12836456|ensembl:ENSP00000362797|uniprotkb:B2R982|uniprotkb:O15185|uniprotkb:Q7Z710|uniprotkb:Q9P2T4|uniprotkb:Q9P2T5	psi-mi:cxcr3_human(display_long)|uniprotkb:CXCR3(gene name)|psi-mi:CXCR3(display_short)|uniprotkb:CKR-L2(gene name synonym)|uniprotkb:G protein-coupled receptor 9(gene name synonym)|uniprotkb:GPR9(gene name synonym)|uniprotkb:Interferon-inducible protein 10 receptor(gene name synonym)	psi-mi:cxcr3_human(display_long)|uniprotkb:CXCR3(gene name)|psi-mi:CXCR3(display_short)|uniprotkb:CKR-L2(gene name synonym)|uniprotkb:G protein-coupled receptor 9(gene name synonym)|uniprotkb:GPR9(gene name synonym)|uniprotkb:Interferon-inducible protein 10 receptor(gene name synonym)	psi-mi:"MI:0012"(bioluminescence resonance energy transfer)	Watts et al. (2013)	imex:IM-26956|pubmed:23170857	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21397074|imex:IM-26956-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0038023"(signaling receptor activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0060326"(cell chemotaxis)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR004070(C-X-C chemokine receptor, type 3)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-380108|reactome:R-HSA-418594|go:"GO:0030155"(regulation of cell adhesion)|ensembl:ENSG00000186810(gene)|ensembl:ENST00000373693(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002685"(regulation of leukocyte migration)|go:"GO:0004950"(chemokine receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010818"(T cell chemotaxis)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019956"(chemokine binding)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0019958"(C-X-C chemokine binding)|refseq:NP_001136269.1|refseq:NP_001495.1|refseq:XP_016884924.1|dip:DIP-5891N	go:"GO:0038023"(signaling receptor activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0060326"(cell chemotaxis)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR004070(C-X-C chemokine receptor, type 3)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-380108|reactome:R-HSA-418594|go:"GO:0030155"(regulation of cell adhesion)|ensembl:ENSG00000186810(gene)|ensembl:ENST00000373693(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002685"(regulation of leukocyte migration)|go:"GO:0004950"(chemokine receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010818"(T cell chemotaxis)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019956"(chemokine binding)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0019958"(C-X-C chemokine binding)|refseq:NP_001136269.1|refseq:NP_001495.1|refseq:XP_016884924.1|dip:DIP-5891N	-	-	-	figure legend:Figure 3, Table 1-4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/04/30	2019/05/22	rogid:P9WxnLkV6IH50a6feWDd6KsoNlA9606	rogid:P9WxnLkV6IH50a6feWDd6KsoNlA9606	rigid:jeB/eTdYkWzl1NOgaTMlyvAiIGU	false	renilla luciferase protein tag:c-c	enhanced yellow fluorescent protein tag:c-c	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:P49682	uniprotkb:P61073	intact:EBI-12836456|ensembl:ENSP00000362797|uniprotkb:B2R982|uniprotkb:O15185|uniprotkb:Q7Z710|uniprotkb:Q9P2T4|uniprotkb:Q9P2T5	intact:EBI-489411|uniprotkb:Q53S69|uniprotkb:O60835|uniprotkb:P30991|uniprotkb:P56438|uniprotkb:Q9UKN2|uniprotkb:B2R5N0|uniprotkb:Q9BXA0|ensembl:ENSP00000241393	psi-mi:cxcr3_human(display_long)|uniprotkb:CXCR3(gene name)|psi-mi:CXCR3(display_short)|uniprotkb:CKR-L2(gene name synonym)|uniprotkb:G protein-coupled receptor 9(gene name synonym)|uniprotkb:GPR9(gene name synonym)|uniprotkb:Interferon-inducible protein 10 receptor(gene name synonym)	psi-mi:cxcr4_human(display_long)|uniprotkb:Stromal cell-derived factor 1 receptor(gene name synonym)|uniprotkb:Fusin(gene name synonym)|uniprotkb:Leukocyte-derived seven transmembrane domain receptor(gene name synonym)|uniprotkb:LCR1(gene name synonym)|uniprotkb:FB22(gene name synonym)|uniprotkb:NPYRL(gene name synonym)|uniprotkb:HM89(gene name synonym)|uniprotkb:CXCR4(gene name)|psi-mi:CXCR4(display_short)|uniprotkb:Lipopolysaccharide-associated protein 3(gene name synonym)	psi-mi:"MI:0012"(bioluminescence resonance energy transfer)	Watts et al. (2013)	imex:IM-26956|pubmed:23170857	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21397082|imex:IM-26956-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0038023"(signaling receptor activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0060326"(cell chemotaxis)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR004070(C-X-C chemokine receptor, type 3)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-380108|reactome:R-HSA-418594|go:"GO:0030155"(regulation of cell adhesion)|ensembl:ENSG00000186810(gene)|ensembl:ENST00000373693(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002685"(regulation of leukocyte migration)|go:"GO:0004950"(chemokine receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010818"(T cell chemotaxis)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019956"(chemokine binding)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0019958"(C-X-C chemokine binding)|refseq:NP_001136269.1|refseq:NP_001495.1|refseq:XP_016884924.1|dip:DIP-5891N	refseq:NP_001008540.1|refseq:NP_003458.1|refseq:NP_001334985.1|refseq:NP_001334988.1|refseq:NP_001334989.1|dip:DIP-34773N|dip:DIP-46290N|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007420"(brain development)|go:"GO:0008038"(neuron recognition)|go:"GO:0009615"(response to virus)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0022029"(telencephalon cell migration)|go:"GO:0030054"(cell junction)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035470"(positive regulation of vascular wound healing)|go:"GO:0035690"|go:"GO:0038147"(C-X-C motif chemokine 12 receptor activity)|go:"GO:0038160"(CXCL12-activated CXCR4 signaling pathway)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR022726|mint:P61073|rcsb pdb:2K03|rcsb pdb:2K04|rcsb pdb:2K05|rcsb pdb:2N55|rcsb pdb:3ODU|rcsb pdb:3OE0|rcsb pdb:3OE6|rcsb pdb:3OE8|rcsb pdb:3OE9|rcsb pdb:4RWS|reactome:R-HSA-173107|reactome:R-HSA-376176|reactome:R-HSA-380108|reactome:R-HSA-418594|go:"GO:0043217"(myelin maintenance)|go:"GO:0043278"(response to morphine)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050792"(regulation of viral process)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1905322"(positive regulation of mesenchymal stem cell migration)|go:"GO:1990478"(response to ultrasound)|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR001277(C-X-C chemokine receptor, type 4)|ensembl:ENSG00000121966(gene)|ensembl:ENST00000241393(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001764"(neuron migration)|go:"GO:0002064"(epithelial cell development)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0003779"(actin binding)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)	-	-	-	figure legend:Figure 3, Table 1-3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/04/30	2019/05/22	rogid:P9WxnLkV6IH50a6feWDd6KsoNlA9606	rogid:/DC0/+M1YsFLLfsDimppXSS/vpQ9606	rigid:Cs898bCY32xzEyBVbVn83zzzKz0	false	renilla luciferase protein tag:c-c	enhanced yellow fluorescent protein tag:c-c	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:P49682	uniprotkb:P29067	intact:EBI-12836456|ensembl:ENSP00000362797|uniprotkb:B2R982|uniprotkb:O15185|uniprotkb:Q7Z710|uniprotkb:Q9P2T4|uniprotkb:Q9P2T5	intact:EBI-1636616|ensembl:ENSRNOP00000026207	psi-mi:cxcr3_human(display_long)|uniprotkb:CXCR3(gene name)|psi-mi:CXCR3(display_short)|uniprotkb:CKR-L2(gene name synonym)|uniprotkb:G protein-coupled receptor 9(gene name synonym)|uniprotkb:GPR9(gene name synonym)|uniprotkb:Interferon-inducible protein 10 receptor(gene name synonym)	psi-mi:arrb2_rat(display_long)|uniprotkb:Arrb2(gene name)|psi-mi:Arrb2(display_short)|uniprotkb:Arrestin beta-2(gene name synonym)	psi-mi:"MI:0012"(bioluminescence resonance energy transfer)	Watts et al. (2013)	imex:IM-26956|pubmed:23170857	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21397093|imex:IM-26956-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0038023"(signaling receptor activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0060326"(cell chemotaxis)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR004070(C-X-C chemokine receptor, type 3)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-380108|reactome:R-HSA-418594|go:"GO:0030155"(regulation of cell adhesion)|ensembl:ENSG00000186810(gene)|ensembl:ENST00000373693(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002685"(regulation of leukocyte migration)|go:"GO:0004950"(chemokine receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010818"(T cell chemotaxis)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019956"(chemokine binding)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0019958"(C-X-C chemokine binding)|refseq:NP_001136269.1|refseq:NP_001495.1|refseq:XP_016884924.1|dip:DIP-5891N	rgd:2157|refseq:NP_037043.1|dip:DIP-40507N|ensembl:ENSRNOG00000019308(gene)|ensembl:ENSRNOT00000026207(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0002032"(desensitization of G protein-coupled receptor signaling pathway by arrestin)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006897"(endocytosis)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031691"(alpha-1A adrenergic receptor binding)|go:"GO:0031692"(alpha-1B adrenergic receptor binding)|go:"GO:0031701"(angiotensin receptor binding)|go:"GO:0031702"(type 1 angiotensin receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031762"(follicle-stimulating hormone receptor binding)|go:"GO:0031826"(type 2A serotonin receptor binding)|go:"GO:0031859"(platelet activating factor receptor binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032226"(positive regulation of synaptic transmission, dopaminergic)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034392"(negative regulation of smooth muscle cell apoptotic process)|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045953"(negative regulation of natural killer cell mediated cytotoxicity)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:1904037"(positive regulation of epithelial cell apoptotic process)|go:"GO:1990763"(arrestin family protein binding)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|rcsb pdb:6K3F|reactome:R-RNO-418555|reactome:R-RNO-456926|reactome:R-RNO-5099900|reactome:R-RNO-5635838|reactome:R-RNO-5674135|reactome:R-RNO-5689880|reactome:R-RNO-8856825|reactome:R-RNO-8856828	-	-	-	figure legend:Figure 4A|agonist:CXCL11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293ft)|taxid:9606(Homo sapiens HEK293FT cell line)	-	2019/04/30	2019/05/22	rogid:P9WxnLkV6IH50a6feWDd6KsoNlA9606	rogid:CmLKfjz9uKH8AcfJcGB/SlhkeuE10116	rigid:pEe9yl8p5Pi/rvbU6zTNWmNgA4Q	false	renilla luciferase protein tag:c-c	venus fluorescent protein tag:c-c	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:P61073	uniprotkb:P29067	intact:EBI-489411|uniprotkb:Q53S69|uniprotkb:O60835|uniprotkb:P30991|uniprotkb:P56438|uniprotkb:Q9UKN2|uniprotkb:B2R5N0|uniprotkb:Q9BXA0|ensembl:ENSP00000241393	intact:EBI-1636616|ensembl:ENSRNOP00000026207	psi-mi:cxcr4_human(display_long)|uniprotkb:Stromal cell-derived factor 1 receptor(gene name synonym)|uniprotkb:Fusin(gene name synonym)|uniprotkb:Leukocyte-derived seven transmembrane domain receptor(gene name synonym)|uniprotkb:LCR1(gene name synonym)|uniprotkb:FB22(gene name synonym)|uniprotkb:NPYRL(gene name synonym)|uniprotkb:HM89(gene name synonym)|uniprotkb:CXCR4(gene name)|psi-mi:CXCR4(display_short)|uniprotkb:Lipopolysaccharide-associated protein 3(gene name synonym)	psi-mi:arrb2_rat(display_long)|uniprotkb:Arrb2(gene name)|psi-mi:Arrb2(display_short)|uniprotkb:Arrestin beta-2(gene name synonym)	psi-mi:"MI:0012"(bioluminescence resonance energy transfer)	Watts et al. (2013)	imex:IM-26956|pubmed:23170857	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21397110|imex:IM-26956-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008540.1|refseq:NP_003458.1|refseq:NP_001334985.1|refseq:NP_001334988.1|refseq:NP_001334989.1|dip:DIP-34773N|dip:DIP-46290N|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007420"(brain development)|go:"GO:0008038"(neuron recognition)|go:"GO:0009615"(response to virus)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0022029"(telencephalon cell migration)|go:"GO:0030054"(cell junction)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035470"(positive regulation of vascular wound healing)|go:"GO:0035690"|go:"GO:0038147"(C-X-C motif chemokine 12 receptor activity)|go:"GO:0038160"(CXCL12-activated CXCR4 signaling pathway)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR022726|mint:P61073|rcsb pdb:2K03|rcsb pdb:2K04|rcsb pdb:2K05|rcsb pdb:2N55|rcsb pdb:3ODU|rcsb pdb:3OE0|rcsb pdb:3OE6|rcsb pdb:3OE8|rcsb pdb:3OE9|rcsb pdb:4RWS|reactome:R-HSA-173107|reactome:R-HSA-376176|reactome:R-HSA-380108|reactome:R-HSA-418594|go:"GO:0043217"(myelin maintenance)|go:"GO:0043278"(response to morphine)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050792"(regulation of viral process)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1905322"(positive regulation of mesenchymal stem cell migration)|go:"GO:1990478"(response to ultrasound)|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR001277(C-X-C chemokine receptor, type 4)|ensembl:ENSG00000121966(gene)|ensembl:ENST00000241393(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001764"(neuron migration)|go:"GO:0002064"(epithelial cell development)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0003779"(actin binding)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)	rgd:2157|refseq:NP_037043.1|dip:DIP-40507N|ensembl:ENSRNOG00000019308(gene)|ensembl:ENSRNOT00000026207(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0002032"(desensitization of G protein-coupled receptor signaling pathway by arrestin)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006897"(endocytosis)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031691"(alpha-1A adrenergic receptor binding)|go:"GO:0031692"(alpha-1B adrenergic receptor binding)|go:"GO:0031701"(angiotensin receptor binding)|go:"GO:0031702"(type 1 angiotensin receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031762"(follicle-stimulating hormone receptor binding)|go:"GO:0031826"(type 2A serotonin receptor binding)|go:"GO:0031859"(platelet activating factor receptor binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032226"(positive regulation of synaptic transmission, dopaminergic)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034392"(negative regulation of smooth muscle cell apoptotic process)|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045953"(negative regulation of natural killer cell mediated cytotoxicity)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:1904037"(positive regulation of epithelial cell apoptotic process)|go:"GO:1990763"(arrestin family protein binding)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|rcsb pdb:6K3F|reactome:R-RNO-418555|reactome:R-RNO-456926|reactome:R-RNO-5099900|reactome:R-RNO-5635838|reactome:R-RNO-5674135|reactome:R-RNO-5689880|reactome:R-RNO-8856825|reactome:R-RNO-8856828	-	-	-	figure legend:Figure 4B/C|agonist:CXCL12|comment:The CXCL12-induced BRET signal for beta-arrestin2-Venus recruitment to CXCR4-Rluc8 was smaller and more transient than that observed in the absence of co-expressed non-tagged CXCR3. A very weak signal was observed with CXCL11 alone, but this signal was increased when both CXCL11 and CXCL12 added simultaneously, giving a  substantially stronger than that observed with CXCL12 alone.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293ft)|taxid:9606(Homo sapiens HEK293FT cell line)	-	2019/04/30	2019/05/22	rogid:/DC0/+M1YsFLLfsDimppXSS/vpQ9606	rogid:CmLKfjz9uKH8AcfJcGB/SlhkeuE10116	rigid:10J1UpS2ZaOPMt4+55evbLoSNB8	false	renilla luciferase protein tag:c-c	venus fluorescent protein tag:c-c	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)