#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O94759	uniprotkb:O94759	intact:EBI-14010782|ensembl:ENSP00000300482|ensembl:ENSP00000381023|uniprotkb:D3DSL6|uniprotkb:Q5KTC2|uniprotkb:Q6J3P5|uniprotkb:Q96KN6|uniprotkb:Q96Q93	intact:EBI-14010782|ensembl:ENSP00000300482|ensembl:ENSP00000381023|uniprotkb:D3DSL6|uniprotkb:Q5KTC2|uniprotkb:Q6J3P5|uniprotkb:Q96KN6|uniprotkb:Q96Q93	psi-mi:trpm2_human(display_long)|uniprotkb:TRPM2(gene name)|psi-mi:TRPM2(display_short)|uniprotkb:EREG1(gene name synonym)|uniprotkb:Estrogen-responsive element-associated gene 1 protein(gene name synonym)|uniprotkb:KNP3(gene name synonym)|uniprotkb:LTRPC2(gene name synonym)|uniprotkb:Long transient receptor potential channel 2(gene name synonym)|uniprotkb:TRPC7(gene name synonym)|uniprotkb:Transient receptor potential channel 7(gene name synonym)|uniprotkb:Transient receptor potential melastatin 2(gene name synonym)	psi-mi:trpm2_human(display_long)|uniprotkb:TRPM2(gene name)|psi-mi:TRPM2(display_short)|uniprotkb:EREG1(gene name synonym)|uniprotkb:Estrogen-responsive element-associated gene 1 protein(gene name synonym)|uniprotkb:KNP3(gene name synonym)|uniprotkb:LTRPC2(gene name synonym)|uniprotkb:Long transient receptor potential channel 2(gene name synonym)|uniprotkb:TRPC7(gene name synonym)|uniprotkb:Transient receptor potential channel 7(gene name synonym)|uniprotkb:Transient receptor potential melastatin 2(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Wang et al. (2018)	pubmed:30467180|imex:IM-27233	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-21005109|wwpdb:6MIX|emdb:EMD-9132|emdb:EMD-9133|wwpdb:6MIZ|wwpdb:6MJ2|emdb:EMD-9134|imex:IM-27233-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142185(gene)|ensembl:ENST00000300482(transcript)|ensembl:ENST00000397928(transcript)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005272"(sodium channel activity)|go:"GO:0005384"(manganese ion transmembrane transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0009408"(response to heat)|go:"GO:0014074"(response to purine-containing compound)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0035579"(specific granule membrane)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0044849"(estrous cycle)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:0071502"(cellular response to temperature stimulus)|go:"GO:0071577"(zinc ion transmembrane transport)|go:"GO:0072571"(mono-ADP-D-ribose binding)|go:"GO:0097028"(dendritic cell differentiation)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0099604"(ligand-gated calcium channel activity)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1903223"(positive regulation of oxidative stress-induced neuron death)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR005821(Ion transport)|interpro:IPR015797(NUDIX)|interpro:IPR029594|interpro:IPR041491|rcsb pdb:6MIX|rcsb pdb:6MIZ|rcsb pdb:6MJ2|rcsb pdb:6PUO|rcsb pdb:6PUR|rcsb pdb:6PUS|rcsb pdb:6PUU|reactome:R-HSA-3295583|reactome:R-HSA-6798695|refseq:NP_001307279.1|refseq:NP_001307280.1|refseq:NP_003298.1|refseq:XP_005261228.1	ensembl:ENSG00000142185(gene)|ensembl:ENST00000300482(transcript)|ensembl:ENST00000397928(transcript)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005272"(sodium channel activity)|go:"GO:0005384"(manganese ion transmembrane transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0009408"(response to heat)|go:"GO:0014074"(response to purine-containing compound)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0035579"(specific granule membrane)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0044849"(estrous cycle)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071415"(cellular response to purine-containing compound)|go:"GO:0071502"(cellular response to temperature stimulus)|go:"GO:0071577"(zinc ion transmembrane transport)|go:"GO:0072571"(mono-ADP-D-ribose binding)|go:"GO:0097028"(dendritic cell differentiation)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0099604"(ligand-gated calcium channel activity)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1903223"(positive regulation of oxidative stress-induced neuron death)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR005821(Ion transport)|interpro:IPR015797(NUDIX)|interpro:IPR029594|interpro:IPR041491|rcsb pdb:6MIX|rcsb pdb:6MIZ|rcsb pdb:6MJ2|rcsb pdb:6PUO|rcsb pdb:6PUR|rcsb pdb:6PUS|rcsb pdb:6PUU|reactome:R-HSA-3295583|reactome:R-HSA-6798695|refseq:NP_001307279.1|refseq:NP_001307280.1|refseq:NP_003298.1|refseq:XP_005261228.1	-	-	-	figure legend:Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line)	-	2018/12/11	2019/07/30	rogid:EZJnjzfD1Jt6T9Fl1A7kg+3oZ1A9606	rogid:EZJnjzfD1Jt6T9Fl1A7kg+3oZ1A9606	rigid:OxlKhzgMdealPdXe6j/9uD0oy7g	false	-	-	4	0	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)