#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q83FA5 uniprotkb:Q9NZJ5 intact:EBI-21284971|ensemblbacteria:AAO89610 intact:EBI-766076|uniprotkb:A0AVH2|uniprotkb:A0AVH1|uniprotkb:B2RCU9|uniprotkb:Q53QY0|uniprotkb:Q53SB1|uniprotkb:O95846|ensembl:ENSP00000307235 psi-mi:y041_coxbu(display_long)|uniprotkb:CBU_0041(locus name) psi-mi:e2ak3_human(display_long)|uniprotkb:PRKR-like endoplasmic reticulum kinase(gene name synonym)|uniprotkb:Pancreatic eIF2-alpha kinase(gene name synonym)|uniprotkb:EIF2AK3(gene name)|psi-mi:EIF2AK3(display_short)|uniprotkb:PEK(gene name synonym)|uniprotkb:PERK(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21284977|imex:IM-26899-101 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO89610(transcript)|ensemblbacteria:CBU_0041(gene)|refseq:NP_819096.1|refseq:WP_010957340.1|mint:Q83FA5 refseq:NP_004827.4|rcsb pdb:4YZS|rcsb pdb:5SV7|rcsb pdb:7MF0|reactome:R-HSA-381042|rcsb pdb:4X7O|ensembl:ENSG00000172071(gene)|ensembl:ENST00000303236(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001503"(ossification)|go:"GO:0001525"(angiogenesis)|go:"GO:0002063"(chondrocyte development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004694"(eukaryotic translation initiation factor 2alpha kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006983"(ER overload response)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010998"(regulation of translational initiation by eIF2 alpha phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030282"(bone mineralization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031642"(negative regulation of myelination)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036492"(eiF2alpha phosphorylation in response to endoplasmic reticulum stress)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060734"(regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:0070417"(cellular response to cold)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902235"(regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1990737"(response to manganese-induced endoplasmic reticulum stress)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q9NZJ5|rcsb pdb:4G31|rcsb pdb:4G34|rcsb pdb:4M7I|rcsb pdb:4X7H|rcsb pdb:4X7J|rcsb pdb:4X7K|rcsb pdb:4X7L|rcsb pdb:4X7N|go:"GO:0051879"(Hsp90 protein binding) - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:BbqKG2wpwMV+ZnUeGk4QizCbmtI227377 rogid:sjPIYQzmbvq1fvSgn0HR781yf9w9606 rigid:K9LKn8FuvoGZY1xuRLgy+ArSpd0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83FA5 uniprotkb:Q12866 intact:EBI-21284971|ensemblbacteria:AAO89610 intact:EBI-2804911|uniprotkb:Q9HBB4|ensembl:ENSP00000295408|ensembl:ENSP00000389152 psi-mi:y041_coxbu(display_long)|uniprotkb:CBU_0041(locus name) psi-mi:mertk_human(display_long)|uniprotkb:MER(gene name synonym)|uniprotkb:Proto-oncogene c-Mer(gene name synonym)|uniprotkb:Receptor tyrosine kinase MerTK(gene name synonym)|uniprotkb:MERTK(gene name)|psi-mi:MERTK(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21284983|imex:IM-26899-103 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO89610(transcript)|ensemblbacteria:CBU_0041(gene)|refseq:NP_819096.1|refseq:WP_010957340.1|mint:Q83FA5 ensembl:ENSG00000153208(gene)|ensembl:ENST00000295408(transcript)|ensembl:ENST00000421804(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006909"(phagocytosis)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0016028"(rhabdomere)|go:"GO:0016477"(cell migration)|go:"GO:0030168"(platelet activation)|go:"GO:0032940"(secretion by cell)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0043235"(receptor complex)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051250"(negative regulation of lymphocyte activation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060068"(vagina development)|go:"GO:0097350"(neutrophil clearance)|go:"GO:2000107"(negative regulation of leukocyte apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036116|interpro:IPR036179|mint:Q12866|rcsb pdb:2DBJ|rcsb pdb:2P0C|rcsb pdb:3BPR|rcsb pdb:3BRB|rcsb pdb:3TCP|rcsb pdb:4M3Q|rcsb pdb:4MH7|rcsb pdb:5K0K|rcsb pdb:5K0X|rcsb pdb:5TC0|rcsb pdb:5TD2|rcsb pdb:5U6C|rcsb pdb:6MEP|rcsb pdb:7AAX|rcsb pdb:7AAY|rcsb pdb:7AAZ|rcsb pdb:7AB0|rcsb pdb:7AB1|rcsb pdb:7AB2|rcsb pdb:4MHA|rcsb pdb:7AVX|rcsb pdb:7AVY|rcsb pdb:7AVZ|rcsb pdb:7AW0|rcsb pdb:7AW1|rcsb pdb:7AW2|rcsb pdb:7AW3|rcsb pdb:7AW4|rcsb pdb:7CQE|rcsb pdb:7OAM|reactome:R-HSA-202733|refseq:NP_006334.2 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:BbqKG2wpwMV+ZnUeGk4QizCbmtI227377 rogid:d1TXRqQHZG+X91BEM32fecg/0bU9606 rigid:m4dbB/Ncfj5XqfnDBcy+sB6bT9s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83FA5 uniprotkb:Q6P4A8 intact:EBI-21284971|ensemblbacteria:AAO89610 intact:EBI-2861204|uniprotkb:Q9BVV3|uniprotkb:Q9H625|uniprotkb:A8K4E9|ensembl:ENSP00000240617 psi-mi:y041_coxbu(display_long)|uniprotkb:CBU_0041(locus name) psi-mi:plbl1_human(display_long)|uniprotkb:PLBD1(gene name)|psi-mi:PLBD1(display_short)|uniprotkb:LAMA-like protein 1(gene name synonym)|uniprotkb:Lamina ancestor homolog 1(gene name synonym)|uniprotkb:Phospholipase B domain-containing protein 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21284989|imex:IM-26899-201 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO89610(transcript)|ensemblbacteria:CBU_0041(gene)|refseq:NP_819096.1|refseq:WP_010957340.1|mint:Q83FA5 refseq:NP_079105.4|ensembl:ENSG00000121316(gene)|ensembl:ENST00000240617(transcript)|go:"GO:0004620"(phospholipase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0009395"(phospholipid catabolic process)|interpro:IPR007000(Laminin A)|interpro:IPR043040|interpro:IPR043041|interpro:IPR043042|mint:Q6P4A8|reactome:R-HSA-1482788|reactome:R-HSA-1482839|reactome:R-HSA-1482922|reactome:R-HSA-1483115 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:BbqKG2wpwMV+ZnUeGk4QizCbmtI227377 rogid:6ZbYKlwkiOBkyp3kckZ4QkLCj689606 rigid:iQAKggyD/1M0RcrA571j9OphqpE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83F71 uniprotkb:P11310 intact:EBI-21284995|ensemblbacteria:AAO89644 intact:EBI-514381|uniprotkb:Q9NYF1|uniprotkb:Q5T4U4|ensembl:ENSP00000359878 psi-mi:q83f71_coxbu(display_long)|uniprotkb:CBU_0077(locus name) psi-mi:acadm_human(display_long)|uniprotkb:Medium chain acyl-CoA dehydrogenase(gene name synonym)|uniprotkb:ACADM(gene name)|psi-mi:ACADM(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285002|imex:IM-26899-541 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO89644(transcript)|ensemblbacteria:CBU_0077(gene)|go:"GO:0016021"(integral component of membrane)|refseq:NP_819130.1|refseq:WP_010957363.1|mint:Q83F71 refseq:NP_000007.1|refseq:NP_001120800.1|dip:DIP-34281N|ensembl:ENSG00000117054(gene)|ensembl:ENST00000370841(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003995"(acyl-CoA dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0009409"(response to cold)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019254"(carnitine metabolic process, CoA-linked)|go:"GO:0030424"(axon)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045329"(carnitine biosynthetic process)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|go:"GO:0051793"(medium-chain fatty acid catabolic process)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR034180|interpro:IPR036250|interpro:IPR037069|mint:P11310|rcsb pdb:1EGC|rcsb pdb:1EGD|rcsb pdb:1EGE|rcsb pdb:1T9G|rcsb pdb:2A1T|rcsb pdb:4P13|reactome:R-HSA-1989781|reactome:R-HSA-77288|reactome:R-HSA-77346|reactome:R-HSA-77348 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JKMfHyEgVdel7cHzOgnLRUH7JWo227377 rogid:rfmTmYKNQr6R6ikvfYovZIctoz49606 rigid:mME0wb4+1HJKUzL3WnxTQjAL+Co false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83F71 uniprotkb:P63146 intact:EBI-21284995|ensemblbacteria:AAO89644 intact:EBI-712629|uniprotkb:P23567|uniprotkb:Q4PJ15|ensembl:ENSP00000265339|uniprotkb:Q9D0J6|uniprotkb:B2R503|uniprotkb:D3DQA2 psi-mi:q83f71_coxbu(display_long)|uniprotkb:CBU_0077(locus name) psi-mi:ube2b_human(display_long)|uniprotkb:Ubiquitin-protein ligase B(gene name synonym)|uniprotkb:Ubiquitin carrier protein B(gene name synonym)|uniprotkb:RAD6 homolog B(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa(gene name synonym)|uniprotkb:UBE2B(gene name)|psi-mi:UBE2B(display_short)|uniprotkb:RAD6B(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme B(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285008|imex:IM-26899-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO89644(transcript)|ensemblbacteria:CBU_0077(gene)|go:"GO:0016021"(integral component of membrane)|refseq:NP_819130.1|refseq:WP_010957363.1|mint:Q83F71 ensembl:ENSG00000119048(gene)|ensembl:ENST00000265339(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001741"(XY body)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007288"(sperm axoneme assembly)|go:"GO:0009411"(response to UV)|go:"GO:0010845"(positive regulation of reciprocal meiotic recombination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR023313|mint:P63146|rcsb pdb:1JAS|rcsb pdb:1NXA|rcsb pdb:2Y4W|rcsb pdb:2YB6|rcsb pdb:2YBF|reactome:R-HSA-110314|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033128"(negative regulation of histone phosphorylation)|go:"GO:0033503"(HULC complex)|go:"GO:0033522"(histone H2A ubiquitination)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0050821"(protein stabilization)|go:"GO:0051026"(chiasma assembly)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070076"(histone lysine demethylation)|go:"GO:0070193"(synaptonemal complex organization)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070829"(obsolete heterochromatin maintenance)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|refseq:NP_003328.1|dip:DIP-29832N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JKMfHyEgVdel7cHzOgnLRUH7JWo227377 rogid:JvcUPH+3qQXicPsIRFnW19NOc3c9606 rigid:Fh16LEJbF/27rBzwUYgfNuwUxWk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83F71 uniprotkb:O95388 intact:EBI-21284995|ensemblbacteria:AAO89644 intact:EBI-1050638|uniprotkb:Q9HCS3|uniprotkb:A8KAG6|uniprotkb:Q5JBS8|ensembl:ENSP00000250160|uniprotkb:E7EMM5|uniprotkb:Q5JBS6|uniprotkb:Q5JBS7 psi-mi:q83f71_coxbu(display_long)|uniprotkb:CBU_0077(locus name) psi-mi:ccn4_human(display_long)|uniprotkb:CCN4(gene name)|psi-mi:CCN4(display_short)|uniprotkb:WISP1(gene name synonym)|uniprotkb:WNT1-inducible-signaling pathway protein 1(gene name synonym)|uniprotkb:Wnt-1-induced secreted protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285014|imex:IM-26899-301 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO89644(transcript)|ensemblbacteria:CBU_0077(gene)|go:"GO:0016021"(integral component of membrane)|refseq:NP_819130.1|refseq:WP_010957363.1|mint:Q83F71 refseq:NP_001191798.1|refseq:NP_003873.1|refseq:NP_543028.1|ensembl:ENST00000250160(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0005178"(integrin binding)|go:"GO:0005520"(insulin-like growth factor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008201"(heparin binding)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0042593"(glucose homeostasis)|ensembl:ENSG00000104415(gene)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0060348"(bone development)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0090303"(positive regulation of wound healing)|interpro:IPR000867(Insulin-like growth factor-binding protein, IGFBP)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR006208(Cystine knot)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR012395(IGFBP-related, CNN)|interpro:IPR017891|interpro:IPR036383|interpro:IPR043973|mint:O95388|go:"GO:0045599"(negative regulation of fat cell differentiation)|refseq:NP_001191799.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JKMfHyEgVdel7cHzOgnLRUH7JWo227377 rogid:ZHPmZwRC/cRYTsWrXTLBoMZiI8k9606 rigid:nsA/OP3BiXmldHJE7lQD8IXjd0U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q820B6 uniprotkb:P08758 intact:EBI-21285020|ensemblbacteria:AAO89735 intact:EBI-296601|ensembl:ENSP00000296511|uniprotkb:Q6FI16|uniprotkb:Q8WV69|uniprotkb:Q6FHB3|uniprotkb:Q9UDH9|uniprotkb:D3DNW7 psi-mi:q820b6_coxbu(display_long)|uniprotkb:CBU_0175(locus name) psi-mi:anxa5_human(display_long)|uniprotkb:ANXA5(gene name)|psi-mi:ANXA5(display_short)|uniprotkb:ANX5(gene name synonym)|uniprotkb:ENX2(gene name synonym)|uniprotkb:PP4(gene name synonym)|uniprotkb:Annexin-5(gene name synonym)|uniprotkb:Annexin V(gene name synonym)|uniprotkb:Lipocortin V(gene name synonym)|uniprotkb:Endonexin II(gene name synonym)|uniprotkb:Calphobindin I(gene name synonym)|uniprotkb:Placental anticoagulant protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein 4(gene name synonym)|uniprotkb:Thromboplastin inhibitor(gene name synonym)|uniprotkb:Vascular anticoagulant-alpha(gene name synonym)|uniprotkb:Anchorin CII(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285030|imex:IM-26899-303 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:CBU_0175(gene)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|ensemblbacteria:AAO89735(transcript)|refseq:NP_819221.1|refseq:WP_010957418.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|mint:Q820B6 ensembl:ENSG00000164111(gene)|ensembl:ENST00000296511(transcript)|go:"GO:0004859"(phospholipase inhibitor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007596"(blood coagulation)|go:"GO:0016020"(membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050819"(negative regulation of coagulation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001464(Annexin)|interpro:IPR002392(Annexin, type V)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P08758|rcsb pdb:1ANW|rcsb pdb:1ANX|rcsb pdb:1AVH|rcsb pdb:1AVR|rcsb pdb:1HAK|rcsb pdb:1HVD|rcsb pdb:1HVE|rcsb pdb:1HVF|rcsb pdb:1HVG|rcsb pdb:1SAV|rcsb pdb:2XO2|rcsb pdb:2XO3|rcsb pdb:6K22|rcsb pdb:6K25|reactome:R-HSA-114608|refseq:NP_001145.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:Id/EXbJk5RDOXZ5nF+ifzUaPfJ0227377 rogid:vIp2wWkAz7uOtQSzbUJick5bT5o9606 rigid:aod9T7pvkEIgZefAST7fYrN+0ug false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q820B6 uniprotkb:O60337 intact:EBI-21285020|ensemblbacteria:AAO89735 intact:EBI-2684600|uniprotkb:A5PKZ4|uniprotkb:O14670|uniprotkb:Q86X77|uniprotkb:D3DTC8|intact:EBI-28971061|ensembl:ENSP00000274140|uniprotkb:B4DKJ2|uniprotkb:B4DT33 psi-mi:q820b6_coxbu(display_long)|uniprotkb:CBU_0175(locus name) psi-mi:marh6_human(display_long)|uniprotkb:MARCHF6(gene name)|psi-mi:MARCHF6(display_short)|uniprotkb:Doa10 homolog(gene name synonym)|uniprotkb:KIAA0597(gene name synonym)|uniprotkb:MARCH6(gene name synonym)|uniprotkb:Membrane-associated RING finger protein 6(gene name synonym)|uniprotkb:Membrane-associated RING-CH protein VI(gene name synonym)|uniprotkb:Protein TEB-4(gene name synonym)|uniprotkb:RING finger protein 176(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MARCHF6(gene name synonym)|uniprotkb:RNF176(gene name synonym)|uniprotkb:TEB4(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285036|imex:IM-26899-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:CBU_0175(gene)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|ensemblbacteria:AAO89735(transcript)|refseq:NP_819221.1|refseq:WP_010957418.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|mint:Q820B6 ensembl:ENSP00000274140|ensembl:ENST00000449913|ensembl:ENSP00000414643|ensembl:ENST00000503788|ensembl:ENSP00000425930|refseq:NP_005876.2|ensembl:ENSG00000145495(gene)|ensembl:ENST00000274140(transcript)|go:"GO:0000835"(ER ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|refseq:NP_001257589.1|refseq:NP_001257590.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:O60337|reactome:R-HSA-901032|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|dip:DIP-56134N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:Id/EXbJk5RDOXZ5nF+ifzUaPfJ0227377 rogid:ow2W2xIcL82tgIHRS0SxlY4Ffjs9606 rigid:rd+zFykkyOZ8tv+zGxg0mhZx9Qs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q820B6 uniprotkb:P46782 intact:EBI-21285020|ensemblbacteria:AAO89735 intact:EBI-350569|uniprotkb:Q96BN0|uniprotkb:B2R4T2|ensembl:ENSP00000196551|ensembl:ENSP00000470114|ensembl:ENSP00000472985 psi-mi:q820b6_coxbu(display_long)|uniprotkb:CBU_0175(locus name) psi-mi:rs5_human(display_long)|uniprotkb:RPS5(gene name)|psi-mi:RPS5(display_short)|uniprotkb:Small ribosomal subunit protein uS7(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285066|imex:IM-26899-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:CBU_0175(gene)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|ensemblbacteria:AAO89735(transcript)|refseq:NP_819221.1|refseq:WP_010957418.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|mint:Q820B6 refseq:NP_001000.2|rcsb pdb:6OLZ|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6Z6M|rcsb pdb:6XA1|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6Y0G|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:5FLX|rcsb pdb:6OLG|rcsb pdb:6OLI|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-72706|ensembl:ENSG00000083845(gene)|ensembl:ENST00000196551(transcript)|ensembl:ENST00000596046(transcript)|ensembl:ENST00000601521(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006450"(regulation of translational fidelity)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000235(Ribosomal protein S7)|interpro:IPR005716(Ribosomal protein S7, eukaryotic/archaeal)|interpro:IPR020606|interpro:IPR023798|interpro:IPR036823|mint:P46782|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|go:"GO:0003735"(structural constituent of ribosome)|rcsb pdb:5AJ0|reactome:R-HSA-72702 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:Id/EXbJk5RDOXZ5nF+ifzUaPfJ0227377 rogid:SoCJdf2InngZZtlz5qD1k5CEfEo9606 rigid:YUUvHygy9RkSNbX3mY4/s+77yec false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q820B6 uniprotkb:Q9NTM9 intact:EBI-21285020|ensemblbacteria:AAO89735 intact:EBI-714918|uniprotkb:Q5TCZ8|uniprotkb:Q9Y321|ensembl:ENSP00000359507 psi-mi:q820b6_coxbu(display_long)|uniprotkb:CBU_0175(locus name) psi-mi:cutc_human(display_long)|uniprotkb:CUTC(gene name)|psi-mi:CUTC(display_short)|uniprotkb:CGI-32(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285042|imex:IM-26899-621 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:CBU_0175(gene)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|ensemblbacteria:AAO89735(transcript)|refseq:NP_819221.1|refseq:WP_010957418.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|mint:Q820B6 ensembl:ENSG00000119929(gene)|ensembl:ENST00000370476(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006825"(copper ion transport)|go:"GO:0051262"(protein tetramerization)|go:"GO:0055070"(copper ion homeostasis)|interpro:IPR005627(CutC)|interpro:IPR023648|interpro:IPR036822|mint:Q9NTM9|refseq:NP_057044.2|reactome:R-HSA-936837|rcsb pdb:3IWP - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:Id/EXbJk5RDOXZ5nF+ifzUaPfJ0227377 rogid:MkxQTQ5IGq+/IZzPy3wSurdtB6w9606 rigid:bcebAC2jLu5CACqhbTxp8UW8CiQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q820B6 uniprotkb:P49257 intact:EBI-21285020|ensemblbacteria:AAO89735 intact:EBI-1057738|uniprotkb:Q9UQG4|uniprotkb:Q9UQG5|uniprotkb:Q9UQG6|uniprotkb:Q9UQG7|uniprotkb:Q9UQG8|uniprotkb:Q9UQG9|uniprotkb:Q9UQH0|uniprotkb:Q9UQH1|uniprotkb:Q9UQH2|uniprotkb:Q12895|uniprotkb:Q8N5I7|uniprotkb:Q9UQG1|uniprotkb:Q9UQG2|uniprotkb:Q9UQG3|ensembl:ENSP00000251047 psi-mi:q820b6_coxbu(display_long)|uniprotkb:CBU_0175(locus name) psi-mi:lman1_human(display_long)|uniprotkb:LMAN1(gene name)|psi-mi:LMAN1(display_short)|uniprotkb:ERGIC53(gene name synonym)|uniprotkb:F5F8D(gene name synonym)|uniprotkb:ER-Golgi intermediate compartment 53 kDa protein(gene name synonym)|uniprotkb:Lectin mannose-binding 1(gene name synonym)|uniprotkb:Gp58(gene name synonym)|uniprotkb:Intracellular mannose-specific lectin MR60(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285048|imex:IM-26899-321 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:CBU_0175(gene)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|ensemblbacteria:AAO89735(transcript)|refseq:NP_819221.1|refseq:WP_010957418.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|mint:Q820B6 refseq:NP_005561.1|ensembl:ENSG00000074695(gene)|ensembl:ENST00000251047(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005537"(mannose binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007596"(blood coagulation)|go:"GO:0010638"(positive regulation of organelle organization)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030017"(sarcomere)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903215"(negative regulation of protein targeting to mitochondrion)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR033085|mint:P49257|rcsb pdb:3A4U|rcsb pdb:3LCP|rcsb pdb:3WHT|rcsb pdb:3WHU|rcsb pdb:3WNX|rcsb pdb:4GKX|rcsb pdb:4GKY|rcsb pdb:4YGB|rcsb pdb:4YGC|rcsb pdb:4YGD|rcsb pdb:4YGE|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-948021|reactome:R-HSA-9013423|dip:DIP-42188N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:Id/EXbJk5RDOXZ5nF+ifzUaPfJ0227377 rogid:CWmvVATvXXjzMqSD0KjTBvmKKuI9606 rigid:dTgVVUj5pJCREXZhGsgMOTy0rKk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q820B6 uniprotkb:P23515 intact:EBI-21285020|ensemblbacteria:AAO89735 intact:EBI-20720752|ensembl:ENSP00000247271|uniprotkb:E1P659 psi-mi:q820b6_coxbu(display_long)|uniprotkb:CBU_0175(locus name) psi-mi:omgp_human(display_long)|uniprotkb:OMG(gene name)|psi-mi:OMG(display_short)|uniprotkb:OMGP(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285054|imex:IM-26899-323 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:CBU_0175(gene)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|ensemblbacteria:AAO89735(transcript)|refseq:NP_819221.1|refseq:WP_010957418.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|mint:Q820B6 ensembl:ENSG00000126861(gene)|ensembl:ENST00000247271(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0031225"(anchored component of membrane)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|mint:P23515|reactome:R-HSA-193634|refseq:NP_002535.3 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:Id/EXbJk5RDOXZ5nF+ifzUaPfJ0227377 rogid:tTKo2vTV2DB2ocBMyTnhwef0w+k9606 rigid:r0Y+f1ANDfZ54Za/aDQzPkY0A1I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q820B6 uniprotkb:Q93062 intact:EBI-21285020|ensemblbacteria:AAO89735 intact:EBI-740322|uniprotkb:Q92516|uniprotkb:Q92517|uniprotkb:Q92518|uniprotkb:Q96J26|uniprotkb:D3DSU9|ensembl:ENSP00000318102|ensembl:ENSP00000380486 psi-mi:q820b6_coxbu(display_long)|uniprotkb:CBU_0175(locus name) psi-mi:rbpms_human(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285060|imex:IM-26899-441 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:CBU_0175(gene)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|ensemblbacteria:AAO89735(transcript)|refseq:NP_819221.1|refseq:WP_010957418.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|mint:Q820B6 refseq:NP_001008710.1|refseq:NP_001008711.1|refseq:NP_001008712.1|refseq:NP_006858.1|ensembl:ENSG00000157110(gene)|ensembl:ENST00000320203(transcript)|ensembl:ENST00000397323(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008143"("poly(A) binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:Q93062|rcsb pdb:1BNY|rcsb pdb:5CYJ|rcsb pdb:5DET|refseq:XP_016868475.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:Id/EXbJk5RDOXZ5nF+ifzUaPfJ0227377 rogid:3PsLJDzqs+19eVFeQlN+yLielYM9606 rigid:uV56NwlhJbF17nUVpjz/yU1Zl4E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q820B6 uniprotkb:Q9Y5X3 intact:EBI-21285020|ensemblbacteria:AAO89735 intact:EBI-715760|uniprotkb:Q52LC4|uniprotkb:B7ZKN3|uniprotkb:Q9BWP0|uniprotkb:Q7KZN0|uniprotkb:D3DW26|ensembl:ENSP00000366988|ensembl:ENSP00000366998 psi-mi:q820b6_coxbu(display_long)|uniprotkb:CBU_0175(locus name) psi-mi:snx5_human(display_long)|uniprotkb:SNX5(gene name)|psi-mi:SNX5(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285072|imex:IM-26899-721 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:CBU_0175(gene)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|ensemblbacteria:AAO89735(transcript)|refseq:NP_819221.1|refseq:WP_010957418.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|mint:Q820B6 refseq:NP_055241.1|refseq:NP_689413.1|ensembl:ENSG00000089006(gene)|ensembl:ENST00000377759(transcript)|ensembl:ENST00000377768(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001891"(phagocytic cup)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006907"(pinocytosis)|go:"GO:0007174"(epidermal growth factor catabolic process)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031313"(extrinsic component of endosome membrane)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034452"(dynactin binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035815"(positive regulation of renal sodium excretion)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070685"(macropinocytic cup)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0097422"(tubular endosome)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028654|interpro:IPR036871|interpro:IPR042135|mint:Q9Y5X3|rcsb pdb:1SYS|rcsb pdb:5TGH|rcsb pdb:5TGI|rcsb pdb:5TGJ|rcsb pdb:5WY2|rcsb pdb:6N5X|rcsb pdb:6N5Y|rcsb pdb:6N5Z|reactome:R-HSA-432722 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:Id/EXbJk5RDOXZ5nF+ifzUaPfJ0227377 rogid:VR2oUxQ4M2bm5zKeHQlao046QL09606 rigid:z4DrhUOs5WhDnxThcjrh4CsMcaM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q820B6 uniprotkb:Q9C030 intact:EBI-21285020|ensemblbacteria:AAO89735 intact:EBI-21285078|uniprotkb:A8K2A7|uniprotkb:B4DDQ5|uniprotkb:Q86WZ8|uniprotkb:Q9HCR1|ensembl:ENSP00000278302 psi-mi:q820b6_coxbu(display_long)|uniprotkb:CBU_0175(locus name) psi-mi:trim6_human(display_long)|uniprotkb:TRIM6(gene name)|psi-mi:TRIM6(display_short)|uniprotkb:RNF89(gene name synonym)|uniprotkb:RING finger protein 89(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM6(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285143|imex:IM-26899-443 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:CBU_0175(gene)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|ensemblbacteria:AAO89735(transcript)|refseq:NP_819221.1|refseq:WP_010957418.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|mint:Q820B6 refseq:NP_001003818.1|refseq:NP_001185573.1|refseq:NP_001185574.1|refseq:NP_477514.1|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032880"(regulation of protein localization)|ensembl:ENSG00000121236(gene)|ensembl:ENST00000278302(transcript)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR027370|interpro:IPR035828|interpro:IPR043136|mint:Q9C030|reactome:R-HSA-877300 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:Id/EXbJk5RDOXZ5nF+ifzUaPfJ0227377 rogid:7zeiA3CcNpnvDcv1wI+2jZRw+1Q9606 rigid:5C5bFPBMo+QQPPj5WZfh5b4pnkQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DF6 uniprotkb:O75936 intact:EBI-21285191|ensemblbacteria:AAO90316 intact:EBI-715662|uniprotkb:Q6IBJ2|ensembl:ENSP00000263182|ensembl:ENSP00000433772|ensembl:ENSP00000434918|ensembl:ENSP00000435781|uniprotkb:B2R8L7|uniprotkb:D3DQZ1 psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name) psi-mi:bodg_human(display_long)|uniprotkb:Gamma-butyrobetaine,2-oxoglutarate dioxygenase(gene name synonym)|uniprotkb:Gamma-butyrobetaine hydroxylase(gene name synonym)|uniprotkb:BBOX1(gene name)|psi-mi:BBOX1(display_short)|uniprotkb:BBH(gene name synonym)|uniprotkb:BBOX(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285230|imex:IM-26899-641 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90316(transcript)|ensemblbacteria:CBU_0781(gene)|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q83DF6 refseq:NP_003977.1|refseq:XP_005253216.1|refseq:XP_005253217.1|refseq:XP_005253218.1|ensembl:ENSG00000129151(gene)|ensembl:ENST00000263182(transcript)|ensembl:ENST00000525090(transcript)|ensembl:ENST00000528583(transcript)|ensembl:ENST00000529202(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008336"(gamma-butyrobetaine dioxygenase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045329"(carnitine biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003819(Taurine catabolism dioxygenase TauD/TfdA)|interpro:IPR010376(Protein of unknown function DUF971)|interpro:IPR012775(Gamma-butyrobetaine,2-oxoglutarate dioxygenase)|interpro:IPR038492|interpro:IPR042098|mint:O75936|rcsb pdb:3MS5|rcsb pdb:3N6W|rcsb pdb:3O2G|rcsb pdb:4BG1|rcsb pdb:4BGK|rcsb pdb:4BGM|rcsb pdb:4BHF|rcsb pdb:4BHG|rcsb pdb:4BHI|rcsb pdb:4C5W|rcsb pdb:4C8R|rcsb pdb:4CWD|reactome:R-HSA-71262|refseq:XP_011518704.1|refseq:XP_016873892.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377 rogid:oEjzTzRRvj9ygqEj2pca6MxK1Jo9606 rigid:voSMywqU1l/hNmm0ZYi9fBibqzc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83E81 uniprotkb:Q9UGI8 intact:EBI-21285176|ensemblbacteria:AAO89998 intact:EBI-2561654|uniprotkb:Q9HAJ9|uniprotkb:Q9GZQ1|uniprotkb:A4D0U6|ensembl:ENSP00000350937 psi-mi:q83e81_coxbu(display_long)|uniprotkb:CBU_0447(locus name) psi-mi:tes_human(display_long)|uniprotkb:TESS(gene name synonym)|uniprotkb:TES(gene name)|psi-mi:TES(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285185|imex:IM-26899-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO89998(transcript)|ensemblbacteria:CBU_0447(gene)|refseq:NP_819484.1|refseq:WP_010957582.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q83E81 refseq:NP_056456.1|refseq:NP_690042.1|ensembl:ENSG00000135269(gene)|ensembl:ENST00000358204(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045296"(cadherin binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR010442(PET)|interpro:IPR027683|interpro:IPR033724|interpro:IPR034958|interpro:IPR034959|interpro:IPR034960|mint:Q9UGI8|rcsb pdb:2IYB|rcsb pdb:2XQN - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:sPpsju+FHsaThB3KcXKrHhNwlxc227377 rogid:19bO7/55OMgcMT5lx1404AluskE9606 rigid:Ebz7tVre6PTHjPZx/xsGyEtYm3s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DF6 uniprotkb:Q9UIF8 intact:EBI-21285191|ensemblbacteria:AAO90316 intact:EBI-741542|ensembl:ENSP00000376534|uniprotkb:Q96EA1|uniprotkb:Q96SQ8|uniprotkb:Q9P252|uniprotkb:Q9Y4N8|uniprotkb:D3DPA8 psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name) psi-mi:baz2b_human(display_long)|uniprotkb:BAZ2B(gene name)|psi-mi:BAZ2B(display_short)|uniprotkb:KIAA1476(gene name synonym)|uniprotkb:hWALp4(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285224|imex:IM-26899-331 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90316(transcript)|ensemblbacteria:CBU_0781(gene)|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q83DF6 ensembl:ENSG00000123636(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090647"(modulation of age-related behavioral decline)|interpro:IPR001487(Bromodomain)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR018359|interpro:IPR018501|interpro:IPR019787|interpro:IPR028941|interpro:IPR036427|interpro:IPR037374|mint:Q9UIF8|rcsb pdb:2E7O|rcsb pdb:3G0L|rcsb pdb:3Q2F|rcsb pdb:4CUP|rcsb pdb:4CUQ|ensembl:ENST00000392783(transcript)|rcsb pdb:4CUR|rcsb pdb:4CUS|rcsb pdb:4CUT|rcsb pdb:4CUU|rcsb pdb:4IR3|rcsb pdb:4IR4|rcsb pdb:4IR5|rcsb pdb:4IR6|rcsb pdb:4NR9|rcsb pdb:4NRA|rcsb pdb:4NRB|rcsb pdb:4NRC|rcsb pdb:4QC1|rcsb pdb:4QC3|rcsb pdb:4QF3|rcsb pdb:4RVR|rcsb pdb:4XUA|refseq:NP_038478.2|rcsb pdb:4XUB|rcsb pdb:5CQ3|rcsb pdb:5CQ4|rcsb pdb:5CQ5|rcsb pdb:5CQ6|rcsb pdb:5CQ7|rcsb pdb:5CQ8|rcsb pdb:5CQA|rcsb pdb:5CU8|rcsb pdb:5CUA|rcsb pdb:5CUB|rcsb pdb:5CUC|rcsb pdb:5CUD|rcsb pdb:5CUE|rcsb pdb:5CUG|rcsb pdb:5DYU|rcsb pdb:5DYX|rcsb pdb:5E73|rcsb pdb:5E74|rcsb pdb:5E9I|rcsb pdb:5E9K|rcsb pdb:5E9L|rcsb pdb:5E9M|rcsb pdb:5PCH|rcsb pdb:5PCI|rcsb pdb:5PCJ|rcsb pdb:5PCK|rcsb pdb:5PCL|rcsb pdb:5PCM|rcsb pdb:5PCN|rcsb pdb:5PCO|rcsb pdb:5PCP|rcsb pdb:5PCQ|rcsb pdb:5PCR|rcsb pdb:5PCS|rcsb pdb:5PCT|rcsb pdb:5PCG|rcsb pdb:5PCU|rcsb pdb:5PCV|rcsb pdb:5PCW|rcsb pdb:5PCX|rcsb pdb:5PCZ|rcsb pdb:5PD0|rcsb pdb:5PD1|rcsb pdb:5L8T|rcsb pdb:5L8U|rcsb pdb:5L96|rcsb pdb:5L97|rcsb pdb:5L98|rcsb pdb:5L99|rcsb pdb:5MGE|rcsb pdb:5MGF|rcsb pdb:5MGG|rcsb pdb:5OR9|rcsb pdb:5ORB|rcsb pdb:5PB7|rcsb pdb:5PB8|rcsb pdb:5PB9|rcsb pdb:5PBA|rcsb pdb:5PBB|rcsb pdb:5PBC|rcsb pdb:5PBD|rcsb pdb:5PBE|rcsb pdb:5PBF|rcsb pdb:5PBG|rcsb pdb:5PBH|rcsb pdb:5PBI|rcsb pdb:5PBJ|rcsb pdb:5PBK|rcsb pdb:5E9Y|rcsb pdb:5PBL|rcsb pdb:5PBM|rcsb pdb:5PBO|rcsb pdb:5PBP|rcsb pdb:5PBQ|rcsb pdb:5PBR|rcsb pdb:5PBS|rcsb pdb:5PBT|rcsb pdb:5PBU|rcsb pdb:5PBV|rcsb pdb:5PBW|rcsb pdb:5PBX|rcsb pdb:5PBY|rcsb pdb:5PBZ|rcsb pdb:5PC0|rcsb pdb:5PC1|rcsb pdb:5PC2|rcsb pdb:5PC3|rcsb pdb:5PC4|rcsb pdb:5PC5|rcsb pdb:5PC6|rcsb pdb:5PC7|rcsb pdb:5PC8|rcsb pdb:5PC9|rcsb pdb:5PCA|rcsb pdb:5PCB|rcsb pdb:5PCC|rcsb pdb:5PBN|rcsb pdb:5PCD|rcsb pdb:5PCE|rcsb pdb:5PCF|rcsb pdb:5PDY|rcsb pdb:5PDZ|rcsb pdb:5PE0|rcsb pdb:5PE1|rcsb pdb:5PE2|rcsb pdb:5PE3|rcsb pdb:5PE4|rcsb pdb:5PE5|rcsb pdb:5PE6|rcsb pdb:5PE7|rcsb pdb:5PE8|rcsb pdb:5PE9|rcsb pdb:5PEA|rcsb pdb:5PEB|rcsb pdb:5PEC|rcsb pdb:5PED|rcsb pdb:5PEE|rcsb pdb:5PEF|rcsb pdb:5PDX|rcsb pdb:5PEG|rcsb pdb:5PEH|rcsb pdb:5PEI|rcsb pdb:5PEJ|rcsb pdb:5PEK|rcsb pdb:5PEL|rcsb pdb:5PEM|rcsb pdb:5PEN|rcsb pdb:5PEO|rcsb pdb:5PD2|rcsb pdb:5PD4|rcsb pdb:5PD5|rcsb pdb:5PD6|rcsb pdb:5PD7|rcsb pdb:5PD8|rcsb pdb:5PD9|rcsb pdb:5PDA|rcsb pdb:5PDB|rcsb pdb:5PDC|rcsb pdb:5PDD|rcsb pdb:5PDE|rcsb pdb:5PDF|rcsb pdb:5PDG|rcsb pdb:5PDH|rcsb pdb:5PDI|rcsb pdb:5PDJ|rcsb pdb:5PD3|rcsb pdb:5PDK|rcsb pdb:5PDL|rcsb pdb:5PDM|rcsb pdb:5PDN|rcsb pdb:5PDO|rcsb pdb:5PDP|rcsb pdb:5PDQ|rcsb pdb:5PDR|rcsb pdb:5PDS|rcsb pdb:5PDT|rcsb pdb:5PDU|rcsb pdb:5PDV|rcsb pdb:5PDW|rcsb pdb:5PFN|rcsb pdb:5PFO|rcsb pdb:5PFP|rcsb pdb:5PFQ|rcsb pdb:5PFR|rcsb pdb:5PFS|rcsb pdb:5PFT|rcsb pdb:5PFU|rcsb pdb:5PFV|rcsb pdb:5PFW|rcsb pdb:5PFX|rcsb pdb:5PFY|rcsb pdb:5PFZ|rcsb pdb:5PG0|rcsb pdb:5PG1|rcsb pdb:5PG2|rcsb pdb:5PG3|rcsb pdb:5PG4|rcsb pdb:5PG5|rcsb pdb:5PG6|rcsb pdb:5PFM|rcsb pdb:5PG7|rcsb pdb:5PG8|rcsb pdb:5PEQ|rcsb pdb:5PES|rcsb pdb:5PET|rcsb pdb:5PEU|rcsb pdb:5PEV|rcsb pdb:5PEW|rcsb pdb:5PEX|rcsb pdb:5PEY|rcsb pdb:5PEZ|rcsb pdb:5PF0|rcsb pdb:5PF1|rcsb pdb:5PF2|rcsb pdb:5PF3|rcsb pdb:5PF4|rcsb pdb:5PF5|rcsb pdb:5PF6|rcsb pdb:5PF7|rcsb pdb:5PF8|rcsb pdb:5PF9|rcsb pdb:5PFA|rcsb pdb:5PFB|rcsb pdb:5PFC|rcsb pdb:5PFD|rcsb pdb:5PER|rcsb pdb:5PFE|rcsb pdb:5PFF|rcsb pdb:5PFG|rcsb pdb:5PFH|rcsb pdb:5PFI|rcsb pdb:5PFJ|rcsb pdb:5PFL|rcsb pdb:5PG9|rcsb pdb:5PGA|rcsb pdb:5PGB|rcsb pdb:5PGC|rcsb pdb:5PGD|rcsb pdb:5PGE|rcsb pdb:5PGF|rcsb pdb:5PGG|rcsb pdb:5PGH|rcsb pdb:5PGI|rcsb pdb:5PGJ|rcsb pdb:5PGK|rcsb pdb:5PGL|rcsb pdb:5PGN|rcsb pdb:5PGO|rcsb pdb:5PGP|rcsb pdb:5PGQ|rcsb pdb:5PGR|rcsb pdb:5PGS|rcsb pdb:5PGT|rcsb pdb:6FGT|rcsb pdb:6FGU|rcsb pdb:6FH6|rcsb pdb:6FH7|rcsb pdb:6FHQ|rcsb pdb:6FI1|ensembl:ENST00000392782|ensembl:ENSP00000376533|ensembl:ENSP00000376534|refseq:NP_001276904.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377 rogid:KpbxkrPxL1uFuikn8vLISOc4wog9606 rigid:QagPTBg/LibE4OUIFHkQkuJQD9Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DF6 uniprotkb:Q5VV63 intact:EBI-21285191|ensemblbacteria:AAO90316 intact:EBI-2682407|uniprotkb:Q6ZSN4|uniprotkb:Q6T256|uniprotkb:Q5JSE8|uniprotkb:Q86WX2|uniprotkb:O60283|uniprotkb:Q5T5Y9|intact:EBI-28971977|ensembl:ENSP00000347152 psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name) psi-mi:atrn1_human(display_long)|uniprotkb:KIAA0534(gene name synonym)|uniprotkb:ATRNL1(gene name)|psi-mi:ATRNL1(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285218|imex:IM-26899-329 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90316(transcript)|ensemblbacteria:CBU_0781(gene)|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q83DF6 ensembl:ENSP00000347152|ensembl:ENST00000609571|ensembl:ENSP00000476902|refseq:NP_997186.1|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000859(CUB)|interpro:IPR001304(C-type lectin)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR002165(Plexin)|ensembl:ENSG00000107518(gene)|interpro:IPR013111(EGF, extracellular)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR016201(Plexin-like fold)|interpro:IPR034011|interpro:IPR035914|ensembl:ENST00000355044(transcript)|go:"GO:0005604"(basement membrane)|mint:Q5VV63|refseq:NP_001263211.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377 rogid:4qYka2D3uDPSg1Fh6WBMMP1MLtE9606 rigid:IjASExPzoS0K+/XI+Soi9RiXQwE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83EM2 uniprotkb:Q9UIF8 intact:EBI-21285149|ensemblbacteria:AAO89852 intact:EBI-741542|ensembl:ENSP00000376534|uniprotkb:Q96EA1|uniprotkb:Q96SQ8|uniprotkb:Q9P252|uniprotkb:Q9Y4N8|uniprotkb:D3DPA8 psi-mi:q83em2_coxbu(display_long)|uniprotkb:CBU_0295(locus name) psi-mi:baz2b_human(display_long)|uniprotkb:BAZ2B(gene name)|psi-mi:BAZ2B(display_short)|uniprotkb:KIAA1476(gene name synonym)|uniprotkb:hWALp4(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285157|imex:IM-26899-543 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO89852(transcript)|ensemblbacteria:CBU_0295(gene)|refseq:NP_819338.1|refseq:WP_010957484.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q83EM2 ensembl:ENSG00000123636(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090647"(modulation of age-related behavioral decline)|interpro:IPR001487(Bromodomain)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR018359|interpro:IPR018501|interpro:IPR019787|interpro:IPR028941|interpro:IPR036427|interpro:IPR037374|mint:Q9UIF8|rcsb pdb:2E7O|rcsb pdb:3G0L|rcsb pdb:3Q2F|rcsb pdb:4CUP|rcsb pdb:4CUQ|ensembl:ENST00000392783(transcript)|rcsb pdb:4CUR|rcsb pdb:4CUS|rcsb pdb:4CUT|rcsb pdb:4CUU|rcsb pdb:4IR3|rcsb pdb:4IR4|rcsb pdb:4IR5|rcsb pdb:4IR6|rcsb pdb:4NR9|rcsb pdb:4NRA|rcsb pdb:4NRB|rcsb pdb:4NRC|rcsb pdb:4QC1|rcsb pdb:4QC3|rcsb pdb:4QF3|rcsb pdb:4RVR|rcsb pdb:4XUA|refseq:NP_038478.2|rcsb pdb:4XUB|rcsb pdb:5CQ3|rcsb pdb:5CQ4|rcsb pdb:5CQ5|rcsb pdb:5CQ6|rcsb pdb:5CQ7|rcsb pdb:5CQ8|rcsb pdb:5CQA|rcsb pdb:5CU8|rcsb pdb:5CUA|rcsb pdb:5CUB|rcsb pdb:5CUC|rcsb pdb:5CUD|rcsb pdb:5CUE|rcsb pdb:5CUG|rcsb pdb:5DYU|rcsb pdb:5DYX|rcsb pdb:5E73|rcsb pdb:5E74|rcsb pdb:5E9I|rcsb pdb:5E9K|rcsb pdb:5E9L|rcsb pdb:5E9M|rcsb pdb:5PCH|rcsb pdb:5PCI|rcsb pdb:5PCJ|rcsb pdb:5PCK|rcsb pdb:5PCL|rcsb pdb:5PCM|rcsb pdb:5PCN|rcsb pdb:5PCO|rcsb pdb:5PCP|rcsb pdb:5PCQ|rcsb pdb:5PCR|rcsb pdb:5PCS|rcsb pdb:5PCT|rcsb pdb:5PCG|rcsb pdb:5PCU|rcsb pdb:5PCV|rcsb pdb:5PCW|rcsb pdb:5PCX|rcsb pdb:5PCZ|rcsb pdb:5PD0|rcsb pdb:5PD1|rcsb pdb:5L8T|rcsb pdb:5L8U|rcsb pdb:5L96|rcsb pdb:5L97|rcsb pdb:5L98|rcsb pdb:5L99|rcsb pdb:5MGE|rcsb pdb:5MGF|rcsb pdb:5MGG|rcsb pdb:5OR9|rcsb pdb:5ORB|rcsb pdb:5PB7|rcsb pdb:5PB8|rcsb pdb:5PB9|rcsb pdb:5PBA|rcsb pdb:5PBB|rcsb pdb:5PBC|rcsb pdb:5PBD|rcsb pdb:5PBE|rcsb pdb:5PBF|rcsb pdb:5PBG|rcsb pdb:5PBH|rcsb pdb:5PBI|rcsb pdb:5PBJ|rcsb pdb:5PBK|rcsb pdb:5E9Y|rcsb pdb:5PBL|rcsb pdb:5PBM|rcsb pdb:5PBO|rcsb pdb:5PBP|rcsb pdb:5PBQ|rcsb pdb:5PBR|rcsb pdb:5PBS|rcsb pdb:5PBT|rcsb pdb:5PBU|rcsb pdb:5PBV|rcsb pdb:5PBW|rcsb pdb:5PBX|rcsb pdb:5PBY|rcsb pdb:5PBZ|rcsb pdb:5PC0|rcsb pdb:5PC1|rcsb pdb:5PC2|rcsb pdb:5PC3|rcsb pdb:5PC4|rcsb pdb:5PC5|rcsb pdb:5PC6|rcsb pdb:5PC7|rcsb pdb:5PC8|rcsb pdb:5PC9|rcsb pdb:5PCA|rcsb pdb:5PCB|rcsb pdb:5PCC|rcsb pdb:5PBN|rcsb pdb:5PCD|rcsb pdb:5PCE|rcsb pdb:5PCF|rcsb pdb:5PDY|rcsb pdb:5PDZ|rcsb pdb:5PE0|rcsb pdb:5PE1|rcsb pdb:5PE2|rcsb pdb:5PE3|rcsb pdb:5PE4|rcsb pdb:5PE5|rcsb pdb:5PE6|rcsb pdb:5PE7|rcsb pdb:5PE8|rcsb pdb:5PE9|rcsb pdb:5PEA|rcsb pdb:5PEB|rcsb pdb:5PEC|rcsb pdb:5PED|rcsb pdb:5PEE|rcsb pdb:5PEF|rcsb pdb:5PDX|rcsb pdb:5PEG|rcsb pdb:5PEH|rcsb pdb:5PEI|rcsb pdb:5PEJ|rcsb pdb:5PEK|rcsb pdb:5PEL|rcsb pdb:5PEM|rcsb pdb:5PEN|rcsb pdb:5PEO|rcsb pdb:5PD2|rcsb pdb:5PD4|rcsb pdb:5PD5|rcsb pdb:5PD6|rcsb pdb:5PD7|rcsb pdb:5PD8|rcsb pdb:5PD9|rcsb pdb:5PDA|rcsb pdb:5PDB|rcsb pdb:5PDC|rcsb pdb:5PDD|rcsb pdb:5PDE|rcsb pdb:5PDF|rcsb pdb:5PDG|rcsb pdb:5PDH|rcsb pdb:5PDI|rcsb pdb:5PDJ|rcsb pdb:5PD3|rcsb pdb:5PDK|rcsb pdb:5PDL|rcsb pdb:5PDM|rcsb pdb:5PDN|rcsb pdb:5PDO|rcsb pdb:5PDP|rcsb pdb:5PDQ|rcsb pdb:5PDR|rcsb pdb:5PDS|rcsb pdb:5PDT|rcsb pdb:5PDU|rcsb pdb:5PDV|rcsb pdb:5PDW|rcsb pdb:5PFN|rcsb pdb:5PFO|rcsb pdb:5PFP|rcsb pdb:5PFQ|rcsb pdb:5PFR|rcsb pdb:5PFS|rcsb pdb:5PFT|rcsb pdb:5PFU|rcsb pdb:5PFV|rcsb pdb:5PFW|rcsb pdb:5PFX|rcsb pdb:5PFY|rcsb pdb:5PFZ|rcsb pdb:5PG0|rcsb pdb:5PG1|rcsb pdb:5PG2|rcsb pdb:5PG3|rcsb pdb:5PG4|rcsb pdb:5PG5|rcsb pdb:5PG6|rcsb pdb:5PFM|rcsb pdb:5PG7|rcsb pdb:5PG8|rcsb pdb:5PEQ|rcsb pdb:5PES|rcsb pdb:5PET|rcsb pdb:5PEU|rcsb pdb:5PEV|rcsb pdb:5PEW|rcsb pdb:5PEX|rcsb pdb:5PEY|rcsb pdb:5PEZ|rcsb pdb:5PF0|rcsb pdb:5PF1|rcsb pdb:5PF2|rcsb pdb:5PF3|rcsb pdb:5PF4|rcsb pdb:5PF5|rcsb pdb:5PF6|rcsb pdb:5PF7|rcsb pdb:5PF8|rcsb pdb:5PF9|rcsb pdb:5PFA|rcsb pdb:5PFB|rcsb pdb:5PFC|rcsb pdb:5PFD|rcsb pdb:5PER|rcsb pdb:5PFE|rcsb pdb:5PFF|rcsb pdb:5PFG|rcsb pdb:5PFH|rcsb pdb:5PFI|rcsb pdb:5PFJ|rcsb pdb:5PFL|rcsb pdb:5PG9|rcsb pdb:5PGA|rcsb pdb:5PGB|rcsb pdb:5PGC|rcsb pdb:5PGD|rcsb pdb:5PGE|rcsb pdb:5PGF|rcsb pdb:5PGG|rcsb pdb:5PGH|rcsb pdb:5PGI|rcsb pdb:5PGJ|rcsb pdb:5PGK|rcsb pdb:5PGL|rcsb pdb:5PGN|rcsb pdb:5PGO|rcsb pdb:5PGP|rcsb pdb:5PGQ|rcsb pdb:5PGR|rcsb pdb:5PGS|rcsb pdb:5PGT|rcsb pdb:6FGT|rcsb pdb:6FGU|rcsb pdb:6FH6|rcsb pdb:6FH7|rcsb pdb:6FHQ|rcsb pdb:6FI1|ensembl:ENST00000392782|ensembl:ENSP00000376533|ensembl:ENSP00000376534|refseq:NP_001276904.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:93t8PoA8XuYP8WAnEuBgVdP88/U227377 rogid:KpbxkrPxL1uFuikn8vLISOc4wog9606 rigid:I3j3qGhKibKQuwN0VT3U4jnDOBM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83ED7 uniprotkb:Q99496 intact:EBI-21285163|ensemblbacteria:AAO89941 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:q83ed7_coxbu(display_long)|uniprotkb:CBU_0388(locus name) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285170|imex:IM-26899-325 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO89941(transcript)|ensemblbacteria:CBU_0388(gene)|go:"GO:0042025"(host cell nucleus)|refseq:NP_819427.1|refseq:WP_010957544.1|mint:Q83ED7 refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:szWBjlt2UW4YQjhWye714QtnMk4227377 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rigid:Ho5LrArnwW9fMnkxxZKQ1n5ydtI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DF6 uniprotkb:P20020 intact:EBI-21285191|ensemblbacteria:AAO90316 intact:EBI-5279998|uniprotkb:Q12992|uniprotkb:Q12993|uniprotkb:Q13819|uniprotkb:Q13820|uniprotkb:Q13821|uniprotkb:Q16504|uniprotkb:Q93082|ensembl:ENSP00000261173|ensembl:ENSP00000392043 psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name) psi-mi:at2b1_human(display_long)|uniprotkb:ATP2B1(gene name)|psi-mi:ATP2B1(display_short)|uniprotkb:PMCA1(gene name synonym)|uniprotkb:Plasma membrane calcium ATPase isoform 1(gene name synonym)|uniprotkb:Plasma membrane calcium pump isoform 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285206|imex:IM-26899-623 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90316(transcript)|ensemblbacteria:CBU_0781(gene)|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q83DF6 refseq:XP_011536709.1|refseq:NP_001001323.1|refseq:NP_001673.2|refseq:XP_016874847.1|reactome:R-HSA-9662360|ensembl:ENSG00000070961(gene)|ensembl:ENST00000261173(transcript)|ensembl:ENST00000428670(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0003056"(regulation of vascular associated smooth muscle contraction)|go:"GO:0003407"(neural retina development)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009409"(response to cold)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015085"(calcium ion transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0034220"(ion transmembrane transport)|interpro:IPR022141|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR030320|interpro:IPR036412|interpro:IPR044492|mint:P20020|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045121"(membrane raft)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6A69|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071305"(cellular response to vitamin D)|go:"GO:0071386"(cellular response to corticosterone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900076"(regulation of cellular response to insulin stimulus)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1905056"(P-type calcium transporter activity involved in regulation of presynaptic cytosolic calcium ion concentration)|go:"GO:1990034"(calcium ion export across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377 rogid:kCpUNLYDF38hciXj32D8rXbXULg9606 rigid:677j1EcJol8wZp4tJSBQye8NAvQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DF6 uniprotkb:O95477 intact:EBI-21285191|ensemblbacteria:AAO90316 intact:EBI-784112|uniprotkb:Q96S56|uniprotkb:Q96T85|uniprotkb:Q9NQV4|uniprotkb:Q9UN06|uniprotkb:Q9UN07|uniprotkb:Q9UN08|uniprotkb:Q9UN09|uniprotkb:Q5VX33|ensembl:ENSP00000363868 psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name) psi-mi:abca1_human(display_long)|uniprotkb:ATP-binding cassette transporter 1(gene name synonym)|uniprotkb:Cholesterol efflux regulatory protein(gene name synonym)|uniprotkb:ABCA1(gene name)|psi-mi:ABCA1(display_short)|uniprotkb:ABC1(gene name synonym)|uniprotkb:CERP(gene name synonym)|uniprotkb:ATP-binding cassette sub-family A member 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285200|imex:IM-26899-545 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90316(transcript)|ensemblbacteria:CBU_0781(gene)|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q83DF6 refseq:NP_005493.2|dip:DIP-29211N|ensembl:ENSG00000165029(gene)|ensembl:ENST00000374736(transcript)|go:"GO:0002790"(peptide secretion)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006497"(protein lipidation)|go:"GO:0006869"(lipid transport)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007040"(lysosome organization)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007584"(response to nutrient)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0009306"(protein secretion)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016197"(endosomal transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0023061"(signal release)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032367"(intracellular cholesterol transport)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034186"(apolipoprotein A-I binding)|go:"GO:0034188"(apolipoprotein A-I receptor activity)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034616"(response to laminar fluid shear stress)|go:"GO:0035690"|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045121"(membrane raft)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046623"(sphingolipid floppase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051117"(ATPase binding)|go:"GO:0055091"(phospholipid homeostasis)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071397"(cellular response to cholesterol)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0071806"(protein transmembrane transport)|go:"GO:0090107"(regulation of high-density lipoprotein particle assembly)|go:"GO:0090108"(positive regulation of high-density lipoprotein particle assembly)|go:"GO:0090554"(phosphatidylcholine floppase activity)|go:"GO:0090556"(phosphatidylserine floppase activity)|go:"GO:0097708"(intracellular vesicle)|go:"GO:0120020"(cholesterol transfer activity)|go:"GO:0140115"(export across plasma membrane)|go:"GO:0140328"(floppase activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR026082|interpro:IPR027417|interpro:IPR030365|mint:O95477|rcsb pdb:5XJY|reactome:R-HSA-1989781|reactome:R-HSA-5682113|reactome:R-HSA-8963896|reactome:R-HSA-9029569 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377 rogid:DtErjp3P9x9wQEBDIbWae+OkfRc9606 rigid:IPSxuxrYz9IcPrzN4UTw4Tf2Yag false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DF6 uniprotkb:Q9Y5K8 intact:EBI-21285191|ensemblbacteria:AAO90316 intact:EBI-2684998|uniprotkb:Q9Y688|uniprotkb:B2RE33|ensembl:ENSP00000216442|ensembl:ENSP00000451167 psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name) psi-mi:vatd_human(display_long)|uniprotkb:ATP6M(gene name synonym)|uniprotkb:VATD(gene name synonym)|uniprotkb:V-ATPase 28 kDa accessory protein(gene name synonym)|uniprotkb:Vacuolar proton pump subunit D(gene name synonym)|uniprotkb:ATP6V1D(gene name)|psi-mi:ATP6V1D(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285212|imex:IM-26899-327 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90316(transcript)|ensemblbacteria:CBU_0781(gene)|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q83DF6 refseq:NP_057078.1|ensembl:ENSG00000100554(gene)|ensembl:ENST00000216442(transcript)|ensembl:ENST00000554087(transcript)|go:"GO:0005765"(lysosomal membrane)|interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|mint:Q9Y5K8|rcsb pdb:6WLZ|go:"GO:0005829"(cytosol)|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-1222556|reactome:R-HSA-6798695|reactome:R-HSA-77387|go:"GO:0005886"(plasma membrane)|reactome:R-HSA-917977|reactome:R-HSA-9639288|reactome:R-HSA-983712|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0033176"(proton-transporting V-type ATPase complex)|go:"GO:0035579"(specific granule membrane)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0070062"(extracellular exosome) - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377 rogid:UBGjCKLxcq9lkUY/Vh6+Kr2i+uk9606 rigid:J1qgi+out/wNCLsFu3LFHdnayi8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DF6 uniprotkb:P10515 intact:EBI-21285191|ensemblbacteria:AAO90316 intact:EBI-2959723|ensembl:ENSP00000280346|uniprotkb:Q16783|uniprotkb:Q53EP3 psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name) psi-mi:odp2_human(display_long)|uniprotkb:DLAT(gene name)|psi-mi:DLAT(display_short)|uniprotkb:DLTA(gene name synonym)|uniprotkb:70 kDa mitochondrial autoantigen of primary biliary cirrhosis(gene name synonym)|uniprotkb:Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:M2 antigen complex 70 kDa subunit(gene name synonym)|uniprotkb:Pyruvate dehydrogenase complex component E2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285260|imex:IM-26899-547 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90316(transcript)|ensemblbacteria:CBU_0781(gene)|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q83DF6 refseq:NP_001922.2|ensembl:ENSG00000150768(gene)|ensembl:ENST00000280346(transcript)|go:"GO:0004742"(dihydrolipoyllysine-residue acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0030431"(sleep)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045254"(pyruvate dehydrogenase complex)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR004167(E3 binding)|interpro:IPR006257(Dihydrolipoamide acetyltransferase, long form)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|interpro:IPR036625|mint:P10515|rcsb pdb:1FYC|rcsb pdb:1Y8N|rcsb pdb:1Y8O|rcsb pdb:1Y8P|rcsb pdb:2DNE|rcsb pdb:2PNR|rcsb pdb:2Q8I|rcsb pdb:3B8K|rcsb pdb:3CRK|rcsb pdb:3CRL|rcsb pdb:6CT0|rcsb pdb:6H55|reactome:R-HSA-204174|reactome:R-HSA-389661|reactome:R-HSA-5362517|reactome:R-HSA-70268|dip:DIP-29496N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377 rogid:Owh80Cm4CXvo2rPKUhLGc/U47co9606 rigid:F4s1DOT6hDDJbWJqw5RjKY/tTHg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DF6 uniprotkb:O15075 intact:EBI-21285191|ensemblbacteria:AAO90316 intact:EBI-2684263|uniprotkb:Q5VZZ1|uniprotkb:B7Z3E9|uniprotkb:Q5VZY8|uniprotkb:Q5VZZ0|ensembl:ENSP00000353846 psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name) psi-mi:dclk1_human(display_long)|uniprotkb:DCAMKL1(gene name synonym)|uniprotkb:DCDC3A(gene name synonym)|uniprotkb:KIAA0369(gene name synonym)|uniprotkb:Doublecortin-like and CAM kinase-like 1(gene name synonym)|uniprotkb:Doublecortin-like kinase 1(gene name synonym)|uniprotkb:Doublecortin domain-containing protein 3A(gene name synonym)|uniprotkb:DCLK1(gene name)|psi-mi:DCLK1(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285254|imex:IM-26899-107 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90316(transcript)|ensemblbacteria:CBU_0781(gene)|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q83DF6 refseq:NP_001182344.1|refseq:NP_001182345.1|refseq:NP_004725.1|ensembl:ENSG00000133083(gene)|ensembl:ENST00000360631(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007399"(nervous system development)|go:"GO:0007417"(central nervous system development)|go:"GO:0009615"(response to virus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016197"(endosomal transport)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0030900"(forebrain development)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048675"(axon extension)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003533(Doublecortin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR036572|mint:O15075|rcsb pdb:1MFW|rcsb pdb:1MG4|rcsb pdb:1UF0|rcsb pdb:5JZJ|rcsb pdb:5JZN|rcsb pdb:6KYQ|rcsb pdb:6KYR|refseq:NP_001317000.1|refseq:NP_001317001.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377 rogid:zCZrL4FeF69gU85zd6h/LE0nDI49606 rigid:p3agzkJALbXnOK8ScPRLQ/b2PGs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DF6 uniprotkb:P00918 intact:EBI-21285191|ensemblbacteria:AAO90316 intact:EBI-724062|ensembl:ENSP00000285379|uniprotkb:Q6FI12|uniprotkb:Q96ET9|uniprotkb:B2R7G8 psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name) psi-mi:cah2_human(display_long)|uniprotkb:Carbonic anhydrase II(gene name synonym)|uniprotkb:Carbonate dehydratase II(gene name synonym)|uniprotkb:Carbonic anhydrase C(gene name synonym)|uniprotkb:CA2(gene name)|psi-mi:CA2(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285236|imex:IM-26899-105 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90316(transcript)|ensemblbacteria:CBU_0781(gene)|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q83DF6 refseq:NP_000058.1|rcsb pdb:5YUI|rcsb pdb:5YUJ|rcsb pdb:5U0G|rcsb pdb:5YUK|rcsb pdb:5ZXW|rcsb pdb:6B4D|rcsb pdb:6B59|rcsb pdb:5ULN|rcsb pdb:6B5A|rcsb pdb:6BBS|rcsb pdb:6BC9|rcsb pdb:6BCC|rcsb pdb:6C7W|rcsb pdb:6C7X|rcsb pdb:6CA2|rcsb pdb:6CEH|rcsb pdb:6CJV|rcsb pdb:6D1L|rcsb pdb:6D1M|rcsb pdb:5UMC|rcsb pdb:5VGY|rcsb pdb:6E8P|rcsb pdb:6E8X|rcsb pdb:6E91|rcsb pdb:6E92|rcsb pdb:6EBE|rcsb pdb:6ECZ|rcsb pdb:6EDA|rcsb pdb:6EEA|rcsb pdb:6EEH|rcsb pdb:6EEO|rcsb pdb:6EQU|rcsb pdb:5W8B|rcsb pdb:6FJI|rcsb pdb:5WEX|rcsb pdb:6FJJ|rcsb pdb:6G3Q|rcsb pdb:6G6T|rcsb pdb:6GCY|rcsb pdb:6GDC|rcsb pdb:6GM9|rcsb pdb:5WG7|rcsb pdb:5WGP|rcsb pdb:5WLR|rcsb pdb:6GOT|rcsb pdb:6GXB|rcsb pdb:5WLT|rcsb pdb:5WLU|rcsb pdb:5WLV|rcsb pdb:5Y2R|rcsb pdb:5Y2S|rcsb pdb:6GXE|rcsb pdb:6H29|rcsb pdb:6H2Z|rcsb pdb:6H33|rcsb pdb:6H34|rcsb pdb:6H3Q|rcsb pdb:6H6S|rcsb pdb:6HD2|rcsb pdb:1BV3|rcsb pdb:1CA2|rcsb pdb:1CA3|rcsb pdb:1CAH|rcsb pdb:1CAI|rcsb pdb:1CAJ|rcsb pdb:1CAK|rcsb pdb:1CAL|rcsb pdb:1CAM|rcsb pdb:1CAN|rcsb pdb:1CAO|rcsb pdb:1CAY|rcsb pdb:1CAZ|rcsb pdb:1CCS|rcsb pdb:1CCT|rcsb pdb:1CCU|rcsb pdb:1CIL|rcsb pdb:1CIM|rcsb pdb:1CIN|rcsb pdb:1CNB|rcsb pdb:1CNC|rcsb pdb:1CNG|rcsb pdb:1CNH|rcsb pdb:1CNI|rcsb pdb:1CNJ|rcsb pdb:1BNW|rcsb pdb:1CNK|rcsb pdb:1CNW|rcsb pdb:1CNX|rcsb pdb:1CNY|rcsb pdb:1CRA|rcsb pdb:1CVA|rcsb pdb:1CVB|rcsb pdb:1IF4|rcsb pdb:1IF5|rcsb pdb:1IF6|rcsb pdb:1IF7|rcsb pdb:1IF8|rcsb pdb:1IF9|rcsb pdb:1KWQ|rcsb pdb:1I9Q|rcsb pdb:1KWR|rcsb pdb:1LG5|rcsb pdb:1LG6|rcsb pdb:1LGD|rcsb pdb:1LUG|rcsb pdb:1LZV|rcsb pdb:1MOO|rcsb pdb:1MUA|rcsb pdb:1OKL|rcsb pdb:1OKM|rcsb pdb:1OKN|rcsb pdb:1OQ5|rcsb pdb:1RAY|rcsb pdb:1RAZ|rcsb pdb:1RZA|rcsb pdb:1RZB|rcsb pdb:1RZC|rcsb pdb:1RZD|rcsb pdb:1RZE|rcsb pdb:1T9N|rcsb pdb:1TB0|rcsb pdb:1TBT|rcsb pdb:1TE3|rcsb pdb:1TEQ|rcsb pdb:1TEU|rcsb pdb:6HR3|rcsb pdb:6HX5|rcsb pdb:6HXD|rcsb pdb:6HZX|rcsb pdb:6I0W|rcsb pdb:6I1U|rcsb pdb:6I2F|rcsb pdb:6I3E|rcsb pdb:6IC2|rcsb pdb:6KLZ|rcsb pdb:6KM0|rcsb pdb:6KM1|rcsb pdb:6KM2|rcsb pdb:6KM3|rcsb pdb:6KM4|rcsb pdb:6KM5|rcsb pdb:6KM6|rcsb pdb:6LUU|rcsb pdb:6LUV|rcsb pdb:6LUW|rcsb pdb:6LUX|rcsb pdb:6LUY|rcsb pdb:6LUZ|rcsb pdb:6LV1|rcsb pdb:6LV2|rcsb pdb:6LV3|rcsb pdb:6LV4|rcsb pdb:6LV5|rcsb pdb:6LV6|rcsb pdb:6LV7|rcsb pdb:6LV8|rcsb pdb:6LV9|rcsb pdb:6HQX|rcsb pdb:6LVA|rcsb pdb:6MBV|rcsb pdb:6MBY|rcsb pdb:6NLV|rcsb pdb:6NM0|rcsb pdb:6ODZ|rcsb pdb:6OE0|rcsb pdb:6OE1|rcsb pdb:6OTI|rcsb pdb:6OTK|rcsb pdb:6OTM|rcsb pdb:6OTO|rcsb pdb:6OTP|rcsb pdb:6OTQ|rcsb pdb:1CVC|rcsb pdb:1CVD|rcsb pdb:1CVE|rcsb pdb:1G46|rcsb pdb:1G48|rcsb pdb:1CVF|rcsb pdb:1CVH|rcsb pdb:1DCA|rcsb pdb:1DCB|rcsb pdb:1EOU|rcsb pdb:1F2W|rcsb pdb:1FQL|rcsb pdb:1FQM|rcsb pdb:1FQN|rcsb pdb:1FQR|rcsb pdb:1FR4|rcsb pdb:1FR7|rcsb pdb:1FSN|rcsb pdb:1FSQ|rcsb pdb:1FSR|rcsb pdb:1G0E|rcsb pdb:1G0F|rcsb pdb:1G1D|rcsb pdb:1G3Z|rcsb pdb:1G45|rcsb pdb:6OUD|rcsb pdb:6OUE|rcsb pdb:6OUF|rcsb pdb:6OUH|rcsb pdb:6OUI|rcsb pdb:6OUJ|rcsb pdb:6OUK|rcsb pdb:6OUM|rcsb pdb:6PDV|rcsb pdb:6PEA|rcsb pdb:6PGX|rcsb pdb:6Q3O|rcsb pdb:6Q9T|rcsb pdb:6QEB|rcsb pdb:6QL1|rcsb pdb:6QL2|rcsb pdb:6QL3|rcsb pdb:6OUB|rcsb pdb:6R6F|rcsb pdb:6R6J|rcsb pdb:6RFH|rcsb pdb:6RG3|rcsb pdb:6RG4|rcsb pdb:6RG5|rcsb pdb:6RH4|rcsb pdb:6RHJ|rcsb pdb:6RHK|rcsb pdb:6RIG|rcsb pdb:6RIT|rcsb pdb:6RJJ|rcsb pdb:6RKN|rcsb pdb:6RL9|rcsb pdb:6RM1|rcsb pdb:6RMP|rcsb pdb:6RMX|rcsb pdb:6RMY|rcsb pdb:6RNP|rcsb pdb:6ROB|rcsb pdb:6ROE|rcsb pdb:6ROF|rcsb pdb:3TVO|rcsb pdb:3U3A|rcsb pdb:3U45|rcsb pdb:3U47|rcsb pdb:3U7C|rcsb pdb:3V2J|rcsb pdb:3TVN|rcsb pdb:3V2M|rcsb pdb:3V3F|rcsb pdb:3V3G|rcsb pdb:3V3H|rcsb pdb:3V3I|rcsb pdb:3V3J|rcsb pdb:3V5G|rcsb pdb:3V7X|rcsb pdb:3VBD|rcsb pdb:3ZP9|rcsb pdb:4BCW|rcsb pdb:4BF1|rcsb pdb:4BF6|rcsb pdb:4CA2|rcsb pdb:4CAC|rcsb pdb:4CQ0|rcsb pdb:4DZ7|rcsb pdb:4DZ9|rcsb pdb:4E3D|rcsb pdb:6RQI|rcsb pdb:6T5C|rcsb pdb:6T7U|rcsb pdb:6T81|rcsb pdb:6T9Z|rcsb pdb:6U4Q|rcsb pdb:6U4T|rcsb pdb:6UFB|rcsb pdb:6UFC|rcsb pdb:6UFD|rcsb pdb:6UGN|rcsb pdb:6UGO|rcsb pdb:6UGP|rcsb pdb:6UGQ|rcsb pdb:6UGR|rcsb pdb:6UGZ|rcsb pdb:6UH0|rcsb pdb:6UX1|rcsb pdb:6UZU|rcsb pdb:6VJ3|rcsb pdb:6VKG|rcsb pdb:1TG3|rcsb pdb:1TG9|rcsb pdb:1TH9|rcsb pdb:1THK|rcsb pdb:1TTM|rcsb pdb:1UGA|rcsb pdb:1UGB|rcsb pdb:1UGC|rcsb pdb:1UGD|rcsb pdb:1UGE|rcsb pdb:1UGF|rcsb pdb:1UGG|rcsb pdb:1XEG|rcsb pdb:1XEV|rcsb pdb:1XPZ|rcsb pdb:1XQ0|rcsb pdb:1YDA|rcsb pdb:1YDB|rcsb pdb:1YDC|rcsb pdb:1YDD|rcsb pdb:1YO0|rcsb pdb:1YO1|rcsb pdb:1YO2|rcsb pdb:1Z9Y|rcsb pdb:1ZE8|rcsb pdb:1ZFK|rcsb pdb:1ZFQ|rcsb pdb:1ZGE|rcsb pdb:4E3F|rcsb pdb:4E3G|rcsb pdb:4E3H|rcsb pdb:4E49|rcsb pdb:4E4A|rcsb pdb:4E5Q|rcsb pdb:4FIK|rcsb pdb:4FL7|rcsb pdb:4FPT|rcsb pdb:4FRC|rcsb pdb:4FU5|rcsb pdb:4FVN|rcsb pdb:4FVO|rcsb pdb:4G0C|rcsb pdb:4GL1|rcsb pdb:4HBA|rcsb pdb:4HEW|rcsb pdb:4HEY|rcsb pdb:4HEZ|rcsb pdb:4HF3|rcsb pdb:4HT0|rcsb pdb:4IDR|rcsb pdb:4ILX|rcsb pdb:4ITO|rcsb pdb:4ITP|rcsb pdb:4IWZ|rcsb pdb:4JS6|rcsb pdb:4JSA|rcsb pdb:4JSS|rcsb pdb:4JSW|rcsb pdb:4JSZ|rcsb pdb:4K0S|rcsb pdb:4K0T|rcsb pdb:4K0Z|rcsb pdb:4K13|rcsb pdb:4K1Q|rcsb pdb:4KAP|rcsb pdb:4KNI|rcsb pdb:4KNJ|rcsb pdb:4KUV|rcsb pdb:4KUW|rcsb pdb:4KUY|rcsb pdb:4KV0|rcsb pdb:4L5U|rcsb pdb:4L5V|rcsb pdb:4L5W|rcsb pdb:4LHI|rcsb pdb:4LP6|rcsb pdb:4M2R|rcsb pdb:4M2U|rcsb pdb:4M2V|rcsb pdb:4M2W|rcsb pdb:4MDG|rcsb pdb:4MDL|rcsb pdb:4MDM|rcsb pdb:4MLT|rcsb pdb:4MLX|rcsb pdb:1ZGF|rcsb pdb:1ZH9|rcsb pdb:1ZSA|rcsb pdb:1ZSB|rcsb pdb:1ZSC|rcsb pdb:2ABE|rcsb pdb:2AW1|rcsb pdb:2AX2|rcsb pdb:2CA2|rcsb pdb:2CBA|rcsb pdb:2CBB|rcsb pdb:2CBC|rcsb pdb:2CBD|rcsb pdb:2CBE|rcsb pdb:2EU2|rcsb pdb:2EU3|rcsb pdb:2EZ7|rcsb pdb:2F14|rcsb pdb:2FMG|rcsb pdb:2FMZ|rcsb pdb:2FNK|rcsb pdb:2FNM|rcsb pdb:2FNN|rcsb pdb:2HOC|rcsb pdb:2FOQ|rcsb pdb:2FOS|rcsb pdb:2ILI|rcsb pdb:2FOU|rcsb pdb:2NNG|rcsb pdb:2NNO|rcsb pdb:2NNS|rcsb pdb:2FOV|rcsb pdb:2GD8|rcsb pdb:2GEH|rcsb pdb:2NNV|rcsb pdb:2NWO|rcsb pdb:2NWP|rcsb pdb:2NWY|rcsb pdb:2NWZ|rcsb pdb:2H15|rcsb pdb:2NXR|rcsb pdb:2NXS|rcsb pdb:2NXT|rcsb pdb:2O4Z|rcsb pdb:2OSF|rcsb pdb:2OSM|rcsb pdb:2POU|rcsb pdb:2POV|rcsb pdb:2POW|rcsb pdb:2H4N|rcsb pdb:2Q1B|rcsb pdb:2Q1Q|rcsb pdb:2Q38|rcsb pdb:2QO8|rcsb pdb:2QOA|rcsb pdb:2QP6|rcsb pdb:2VVA|rcsb pdb:2VVB|rcsb pdb:2HD6|rcsb pdb:2HKK|rcsb pdb:2WD2|rcsb pdb:2WD3|rcsb pdb:2HL4|rcsb pdb:2HNC|rcsb pdb:2WEG|rcsb pdb:2WEH|rcsb pdb:2WEJ|rcsb pdb:2WEO|rcsb pdb:4MTY|rcsb pdb:4N0X|rcsb pdb:4N16|rcsb pdb:4PQ7|rcsb pdb:4PXX|rcsb pdb:4PYX|rcsb pdb:4PYY|rcsb pdb:4PZH|rcsb pdb:4Q06|rcsb pdb:4Q07|rcsb pdb:4Q08|rcsb pdb:4Q09|rcsb pdb:4Q49|rcsb pdb:4Q6D|rcsb pdb:4Q6E|rcsb pdb:4Q78|rcsb pdb:4Q7P|rcsb pdb:4Q7S|rcsb pdb:4Q7V|rcsb pdb:4Q7W|rcsb pdb:4Q81|rcsb pdb:4Q83|rcsb pdb:4Q87|rcsb pdb:4Q8X|rcsb pdb:4Q8Y|rcsb pdb:4Q8Z|rcsb pdb:4Q90|rcsb pdb:4Q99|rcsb pdb:4Q9Y|rcsb pdb:4QEF|rcsb pdb:4QIY|rcsb pdb:4QJM|rcsb pdb:4QK1|rcsb pdb:4QK2|rcsb pdb:4QK3|rcsb pdb:4QSA|rcsb pdb:4QSB|rcsb pdb:4QSI|rcsb pdb:4QTL|rcsb pdb:4QY3|rcsb pdb:4R59|rcsb pdb:4R5A|rcsb pdb:4R5B|rcsb pdb:4RFC|rcsb pdb:4RFD|rcsb pdb:4RH2|rcsb pdb:4RIU|rcsb pdb:4RIV|rcsb pdb:4RN4|rcsb pdb:4RUX|rcsb pdb:4RUY|rcsb pdb:4RUZ|rcsb pdb:4WL4|rcsb pdb:4WW6|rcsb pdb:4MO8|rcsb pdb:4XE1|rcsb pdb:4Y0J|rcsb pdb:4YGJ|rcsb pdb:4YGK|rcsb pdb:4YGL|rcsb pdb:4YGN|rcsb pdb:4YVY|rcsb pdb:4YWP|rcsb pdb:4YX4|rcsb pdb:4YXI|rcsb pdb:4YXO|rcsb pdb:6RRI|rcsb pdb:6RS5|rcsb pdb:6RSZ|rcsb pdb:6RVF|rcsb pdb:6RVK|rcsb pdb:6RVL|rcsb pdb:6RW1|rcsb pdb:6RZX|rcsb pdb:6S03|rcsb pdb:6S9G|rcsb pdb:6S9Z|rcsb pdb:6SAC|rcsb pdb:6SAS|rcsb pdb:6SAY|rcsb pdb:6SB7|rcsb pdb:6SBH|rcsb pdb:6SBL|rcsb pdb:6SBM|rcsb pdb:6SD7|rcsb pdb:6SDH|rcsb pdb:6SDI|rcsb pdb:6SDJ|rcsb pdb:6SDL|rcsb pdb:6SDS|rcsb pdb:6SEY|rcsb pdb:6RRG|rcsb pdb:6SFQ|rcsb pdb:6SFU|rcsb pdb:6SG0|rcsb pdb:6SG6|rcsb pdb:6SX9|rcsb pdb:6SYB|rcsb pdb:6SYS|rcsb pdb:6T4N|rcsb pdb:6T4O|rcsb pdb:6T4P|rcsb pdb:2X7S|rcsb pdb:2X7T|rcsb pdb:2X7U|rcsb pdb:3B4F|rcsb pdb:3BET|rcsb pdb:3BL0|rcsb pdb:3BL1|rcsb pdb:3C7P|rcsb pdb:3CA2|rcsb pdb:3CAJ|rcsb pdb:3CYU|rcsb pdb:3D8W|rcsb pdb:3D92|rcsb pdb:3D93|rcsb pdb:3D9Z|rcsb pdb:3DAZ|rcsb pdb:3DBU|rcsb pdb:3DC3|rcsb pdb:3DC9|rcsb pdb:3DCC|rcsb pdb:3DCS|rcsb pdb:3DCW|rcsb pdb:3DD0|rcsb pdb:3DD8|rcsb pdb:3DV7|rcsb pdb:3DVB|rcsb pdb:3DVC|rcsb pdb:3DVD|rcsb pdb:3EFI|rcsb pdb:3EFT|rcsb pdb:4YYT|rcsb pdb:4Z0Q|rcsb pdb:4Z1E|rcsb pdb:4Z1J|rcsb pdb:4Z1K|rcsb pdb:4Z1N|rcsb pdb:4ZAO|rcsb pdb:4ZWI|rcsb pdb:4ZWX|rcsb pdb:4ZWY|rcsb pdb:4ZWZ|rcsb pdb:4ZX0|rcsb pdb:4ZX1|rcsb pdb:5A6H|rcsb pdb:5AMD|rcsb pdb:5AMG|rcsb pdb:5AML|rcsb pdb:5BNL|rcsb pdb:5BRU|rcsb pdb:5BRV|rcsb pdb:5BRW|rcsb pdb:5BYI|rcsb pdb:5C8I|rcsb pdb:5CA2|rcsb pdb:5CAC|rcsb pdb:5CLU|rcsb pdb:5DOG|rcsb pdb:5DOH|rcsb pdb:5DRS|rcsb pdb:5DSK|rcsb pdb:5DSL|rcsb pdb:5DSM|rcsb pdb:5DSO|rcsb pdb:5DSP|rcsb pdb:4YXU|rcsb pdb:5DSQ|rcsb pdb:5DSR|rcsb pdb:5E28|rcsb pdb:5E2K|rcsb pdb:5E2R|rcsb pdb:5E2S|rcsb pdb:5EH5|rcsb pdb:5EH7|rcsb pdb:5EH8|rcsb pdb:5EHE|rcsb pdb:5EHV|rcsb pdb:5EHW|rcsb pdb:5EIJ|rcsb pdb:5EKH|rcsb pdb:3F4X|rcsb pdb:3F8E|rcsb pdb:3FFP|rcsb pdb:3GZ0|rcsb pdb:3HFP|rcsb pdb:3HKN|rcsb pdb:3HKQ|rcsb pdb:3HKT|rcsb pdb:3HKU|rcsb pdb:3HLJ|rcsb pdb:3HS4|rcsb pdb:3IBI|rcsb pdb:3IBL|rcsb pdb:3IBN|rcsb pdb:3IBU|rcsb pdb:3IEO|rcsb pdb:3IGP|rcsb pdb:3K2F|rcsb pdb:3K34|rcsb pdb:3K7K|rcsb pdb:3KIG|rcsb pdb:3KKX|rcsb pdb:3KNE|rcsb pdb:3KOI|rcsb pdb:3KOK|rcsb pdb:3KON|rcsb pdb:3KS3|rcsb pdb:3KWA|rcsb pdb:3L14|rcsb pdb:3M04|rcsb pdb:3M14|rcsb pdb:3M1J|rcsb pdb:3M1K|rcsb pdb:3M1Q|rcsb pdb:3M1W|rcsb pdb:3M2N|rcsb pdb:3M2X|rcsb pdb:3M2Y|rcsb pdb:3M2Z|rcsb pdb:3M3X|rcsb pdb:3M40|rcsb pdb:3M5E|rcsb pdb:3M5S|rcsb pdb:3M5T|rcsb pdb:3M67|rcsb pdb:3M96|rcsb pdb:3M98|rcsb pdb:3MHC|rcsb pdb:3MHI|rcsb pdb:3MHL|rcsb pdb:3MHM|rcsb pdb:3MHO|rcsb pdb:3ML2|rcsb pdb:3MMF|rcsb pdb:3MNA|rcsb pdb:3MNH|rcsb pdb:3MNI|rcsb pdb:3MNJ|rcsb pdb:3MNK|rcsb pdb:3MNU|rcsb pdb:3MWO|rcsb pdb:3MYQ|rcsb pdb:3MZC|rcsb pdb:3N0N|rcsb pdb:3N2P|rcsb pdb:5EKM|rcsb pdb:5EOI|rcsb pdb:5FDC|rcsb pdb:5FDI|rcsb pdb:5FLO|rcsb pdb:5FLP|rcsb pdb:5FLQ|rcsb pdb:5FLR|rcsb pdb:5FLS|rcsb pdb:5FLT|rcsb pdb:5FNG|rcsb pdb:5FNH|rcsb pdb:5FNI|rcsb pdb:5FNJ|rcsb pdb:5FNK|rcsb pdb:5FNL|rcsb pdb:5FNM|rcsb pdb:5G01|rcsb pdb:5G03|rcsb pdb:5G0B|rcsb pdb:5G0C|rcsb pdb:5GMN|rcsb pdb:5J8Z|rcsb pdb:5EKJ|rcsb pdb:3N4B|rcsb pdb:3N3J|rcsb pdb:3NB5|rcsb pdb:3NI5|rcsb pdb:3NJ9|rcsb pdb:3OIK|rcsb pdb:3OIL|rcsb pdb:3OIM|rcsb pdb:3OKU|rcsb pdb:3OKV|rcsb pdb:3OY0|rcsb pdb:3OYQ|rcsb pdb:3OYS|rcsb pdb:3P3H|rcsb pdb:3P3J|rcsb pdb:3P44|rcsb pdb:3P4V|rcsb pdb:3P55|rcsb pdb:3P58|rcsb pdb:3P5A|rcsb pdb:3P5L|rcsb pdb:3PJJ|rcsb pdb:3PO6|rcsb pdb:5JE7|rcsb pdb:5JEG|rcsb pdb:5JEH|rcsb pdb:5JEP|rcsb pdb:5JES|rcsb pdb:5JG3|rcsb pdb:5JG5|rcsb pdb:5JGS|rcsb pdb:5JGT|rcsb pdb:5JMZ|rcsb pdb:5JN3|rcsb pdb:5JN7|rcsb pdb:5JQ0|rcsb pdb:5JQT|rcsb pdb:5L3O|rcsb pdb:5L6K|rcsb pdb:5L6T|rcsb pdb:5L70|rcsb pdb:5L9E|rcsb pdb:5JDV|rcsb pdb:5LJQ|rcsb pdb:5LJT|rcsb pdb:5LL4|rcsb pdb:5LL8|rcsb pdb:5LLC|rcsb pdb:5LLE|rcsb pdb:5LLG|rcsb pdb:5LLH|rcsb pdb:5LMD|rcsb pdb:5LVS|rcsb pdb:5M78|rcsb pdb:5MJN|rcsb pdb:5N0D|rcsb pdb:5N0E|rcsb pdb:5N1R|rcsb pdb:5N1S|rcsb pdb:5N24|rcsb pdb:5N25|rcsb pdb:5NEA|rcsb pdb:5NEE|rcsb pdb:5NXG|ensembl:ENSG00000104267(gene)|ensembl:ENST00000285379(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0004064"(arylesterase activity)|go:"GO:0004089"(carbonate dehydratase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009268"(response to pH)|go:"GO:0010043"(response to zinc ion)|go:"GO:0015670"(carbon dioxide transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016836"(hydro-lyase activity)|go:"GO:0030424"(axon)|go:"GO:0032849"(positive regulation of cellular pH reduction)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043627"(response to estrogen)|go:"GO:0044070"(regulation of anion transport)|rcsb pdb:1G4O|rcsb pdb:1G52|rcsb pdb:1G53|rcsb pdb:1G54|rcsb pdb:1H4N|rcsb pdb:1H9N|rcsb pdb:1H9Q|rcsb pdb:1HCA|rcsb pdb:1G4J|rcsb pdb:1HEA|rcsb pdb:1HEB|rcsb pdb:1HEC|rcsb pdb:1HED|rcsb pdb:1HVA|rcsb pdb:1I8Z|rcsb pdb:1I90|rcsb pdb:1I91|rcsb pdb:1I9L|rcsb pdb:1I9M|rcsb pdb:1I9N|rcsb pdb:1I9O|rcsb pdb:1I9P|rcsb pdb:3QYK|rcsb pdb:3R16|rcsb pdb:3R17|rcsb pdb:3RG3|rcsb pdb:3RG4|rcsb pdb:3RGE|rcsb pdb:3RJ7|rcsb pdb:3RLD|rcsb pdb:3RYJ|rcsb pdb:3RYV|rcsb pdb:3RYX|rcsb pdb:3RYY|rcsb pdb:3RYZ|rcsb pdb:3RZ0|rcsb pdb:3RZ1|rcsb pdb:3PYK|rcsb pdb:3RZ5|rcsb pdb:3RZ7|rcsb pdb:3RZ8|rcsb pdb:3S71|rcsb pdb:3S72|rcsb pdb:3S73|rcsb pdb:3S74|rcsb pdb:3S75|rcsb pdb:3S76|rcsb pdb:3S77|rcsb pdb:3S78|rcsb pdb:3S8X|rcsb pdb:3S9T|rcsb pdb:3SAP|rcsb pdb:3SAX|rcsb pdb:3SBH|rcsb pdb:3SBI|rcsb pdb:3T5U|rcsb pdb:3T5Z|rcsb pdb:3T82|rcsb pdb:3T83|rcsb pdb:3T84|rcsb pdb:3T85|rcsb pdb:3TMJ|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:2001150"(positive regulation of dipeptide transmembrane transport)|interpro:IPR001148(Carbonic anhydrase, eukaryotic)|interpro:IPR018338|interpro:IPR023561|interpro:IPR036398|mint:P00918|rcsb pdb:12CA|rcsb pdb:1A42|rcsb pdb:1AM6|rcsb pdb:1AVN|rcsb pdb:1BCD|rcsb pdb:1BIC|rcsb pdb:1BN1|rcsb pdb:1BN3|rcsb pdb:1BN4|rcsb pdb:1BNM|rcsb pdb:1BNN|rcsb pdb:1BNQ|rcsb pdb:1BNT|rcsb pdb:1BNU|rcsb pdb:1BNV|rcsb pdb:5NXI|rcsb pdb:5NY3|rcsb pdb:5NY6|rcsb pdb:5NYA|rcsb pdb:5O07|rcsb pdb:5OGN|rcsb pdb:5OGO|rcsb pdb:5OGP|rcsb pdb:5SZ0|rcsb pdb:5SZ1|rcsb pdb:5SZ2|rcsb pdb:5NXM|rcsb pdb:5NXO|rcsb pdb:5SZ3|rcsb pdb:5SZ4|rcsb pdb:5SZ5|rcsb pdb:5SZ6|rcsb pdb:5NXP|rcsb pdb:5SZ7|rcsb pdb:5T71|rcsb pdb:5T72|rcsb pdb:5T74|rcsb pdb:5T75|rcsb pdb:5TFX|rcsb pdb:5TH4|rcsb pdb:5THI|rcsb pdb:5THJ|rcsb pdb:5THN|rcsb pdb:5TI0|rcsb pdb:5TXY|rcsb pdb:5TY1|rcsb pdb:5TY8|rcsb pdb:5TY9|rcsb pdb:5NXV|rcsb pdb:5NXW|rcsb pdb:5NY1|rcsb pdb:5TYA|rcsb pdb:5U0D|rcsb pdb:5U0E|rcsb pdb:5U0F|rcsb pdb:6WKA|rcsb pdb:6WQ4|rcsb pdb:6WQ5|rcsb pdb:6WQ7|rcsb pdb:6WQ8|rcsb pdb:6WQ9|rcsb pdb:6XVH|rcsb pdb:6XWZ|rcsb pdb:6XXT|rcsb pdb:6YH4|rcsb pdb:6YH5|rcsb pdb:6YH6|rcsb pdb:6YH7|rcsb pdb:6YH8|rcsb pdb:6YH9|rcsb pdb:6YHA|rcsb pdb:6YHB|rcsb pdb:6YHC|rcsb pdb:6YJ3|rcsb pdb:6YKC|rcsb pdb:6YKH|rcsb pdb:6YMA|rcsb pdb:6YMB|rcsb pdb:6YO2|rcsb pdb:6YO4|rcsb pdb:6YO7|rcsb pdb:6YOI|rcsb pdb:6YOK|rcsb pdb:6YOL|rcsb pdb:6YPW|rcsb pdb:6YQT|rcsb pdb:6YQU|rcsb pdb:6YRI|rcsb pdb:6YZJ|rcsb pdb:6YZK|rcsb pdb:6YZL|rcsb pdb:6YZT|rcsb pdb:6YZU|rcsb pdb:6YZV|rcsb pdb:6YZM|rcsb pdb:6YZW|rcsb pdb:6YZX|rcsb pdb:6Z04|rcsb pdb:6ZR8|rcsb pdb:6YZN|rcsb pdb:6YZO|rcsb pdb:7BI5|rcsb pdb:7CA2|rcsb pdb:7JNR|rcsb pdb:7JNV|rcsb pdb:7JNW|rcsb pdb:7JNX|rcsb pdb:7JNZ|rcsb pdb:7JO0|rcsb pdb:7JO1|rcsb pdb:7JO2|rcsb pdb:7JO3|rcsb pdb:7JOB|rcsb pdb:7JOC|rcsb pdb:7K6I|rcsb pdb:7K6J|rcsb pdb:7K6K|rcsb pdb:7K6L|rcsb pdb:7K6T|rcsb pdb:7K6U|rcsb pdb:7K6X|rcsb pdb:7K6Z|rcsb pdb:8CA2|rcsb pdb:9CA2|reactome:R-HSA-1237044|reactome:R-HSA-1247673|reactome:R-HSA-1475029|rcsb pdb:6YZP|rcsb pdb:6YZQ|rcsb pdb:6YZR|rcsb pdb:6YZS - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377 rogid:Er5rv/L2XS7uyrm/fPxFFsN+EsU9606 rigid:SUsW/LV0bql9AbWP9EH6clpLE+g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DF6 uniprotkb:O94921 intact:EBI-21285191|ensemblbacteria:AAO90316 intact:EBI-1043945|uniprotkb:Q75N06|uniprotkb:Q75N22|uniprotkb:Q8N764|uniprotkb:Q9H3D7|uniprotkb:Q9UDR0|uniprotkb:A6NK51|uniprotkb:A4D1E6|uniprotkb:A8WFP6|uniprotkb:B4DHG5|uniprotkb:B4DNM2|ensembl:ENSP00000369390 psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name) psi-mi:cdk14_human(display_long)|uniprotkb:CDK14(gene name)|psi-mi:CDK14(display_short)|uniprotkb:KIAA0834(gene name synonym)|uniprotkb:PFTK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PFTAIRE-1(gene name synonym)|uniprotkb:Cell division protein kinase 14(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285242|imex:IM-26899-333 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90316(transcript)|ensemblbacteria:CBU_0781(gene)|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q83DF6 refseq:NP_036527.1|refseq:XP_005250495.1|refseq:XP_005250496.1|refseq:NP_001274064.1|refseq:NP_001274065.1|refseq:NP_001274066.1|refseq:XP_011514608.1|refseq:XP_016867809.1|refseq:XP_016867810.1|refseq:XP_016867811.1|dip:DIP-39618N|ensembl:ENSG00000058091(gene)|ensembl:ENST00000380050(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000308"(cytoplasmic cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030332"(cyclin binding)|go:"GO:0051301"(cell division)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:O94921 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377 rogid:7qBB2uRgR1pz0G9qLYJ7i+GGMuk9606 rigid:o61UukmNpy5eB7jwBjGnd7M3y6Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DF6 uniprotkb:Q9Y6G5 intact:EBI-21285191|ensemblbacteria:AAO90316 intact:EBI-1550310|uniprotkb:Q9P077|uniprotkb:D3DT07|ensembl:ENSP00000274458 psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name) psi-mi:comda_human(display_long)|uniprotkb:COMMD10(gene name)|psi-mi:COMMD10(display_short)|uniprotkb:HSPC305(orf name)|uniprotkb:PTD002(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285248|imex:IM-26899-643 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90316(transcript)|ensemblbacteria:CBU_0781(gene)|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q83DF6 refseq:NP_057228.1|refseq:NP_001295009.1|ensembl:ENSG00000145781(gene)|ensembl:ENST00000274458(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|interpro:IPR017920|interpro:IPR037361|mint:Q9Y6G5|reactome:R-HSA-8951664 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377 rogid:yRozKabxLJMAEbM9QfLGOQCzRxE9606 rigid:4UKp1/AC9Y+jJsERxnVtKp8xW4g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DF6 uniprotkb:Q14766 intact:EBI-21285191|ensemblbacteria:AAO90316 intact:EBI-947693|uniprotkb:A1L3V1|uniprotkb:P22064|uniprotkb:Q53SD8|uniprotkb:Q53SF3|uniprotkb:Q53SG1|uniprotkb:Q59HF7|uniprotkb:Q8TD95|ensembl:ENSP00000386043 psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name) psi-mi:ltbp1_human(display_long)|uniprotkb:LTBP1(gene name)|psi-mi:LTBP1(display_short)|uniprotkb:Transforming growth factor beta-1-binding protein 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285296|imex:IM-26899-447 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90316(transcript)|ensemblbacteria:CBU_0781(gene)|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q83DF6 refseq:NP_000618.3|refseq:NP_001159736.1|refseq:NP_001159737.1|refseq:NP_001159738.1|refseq:NP_996826.2|refseq:XP_011531155.1|dip:DIP-50011N|ensembl:ENSG00000049323(gene)|ensembl:ENST00000404816(transcript)|go:"GO:0001527"(microfibril)|go:"GO:0005024"(transforming growth factor beta-activated receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035583"(sequestering of TGFbeta in extracellular matrix)|go:"GO:0050431"(transforming growth factor beta binding)|go:"GO:0050436"(microfibril binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:1901388"(regulation of transforming growth factor beta activation)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR017878|interpro:IPR018097|interpro:IPR026823|interpro:IPR036773|mint:Q14766|rcsb pdb:1KSQ|reactome:R-HSA-2129379|reactome:R-HSA-381426|reactome:R-HSA-8957275 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377 rogid:OgHGfOcQWdQuLUT85Xg04lfggcs9606 rigid:ubPnm4xFNpISXSENZVf0wjpAaG0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DF6 uniprotkb:Q99538 intact:EBI-21285191|ensemblbacteria:AAO90316 intact:EBI-2511794|ensembl:ENSP00000334052|ensembl:ENSP00000376911|uniprotkb:Q86TV2|uniprotkb:Q86TV3|uniprotkb:Q9BTY1|uniprotkb:O00123|intact:EBI-10963477 psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name) psi-mi:lgmn_human(display_long)|uniprotkb:LGMN(gene name)|psi-mi:LGMN(display_short)|uniprotkb:PRSC1(gene name synonym)|uniprotkb:Asparaginyl endopeptidase(gene name synonym)|uniprotkb:Protease, cysteine 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285290|imex:IM-26899-109 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90316(transcript)|ensemblbacteria:CBU_0781(gene)|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q83DF6 ensembl:ENSG00000100600(gene)|ensembl:ENST00000334869(transcript)|ensembl:ENST00000393218(transcript)|go:"GO:0003014"(renal system process)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0006508"(proteolysis)|go:"GO:0006624"(vacuolar protein processing)|go:"GO:0007613"(memory)|go:"GO:0008233"(peptidase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008306"(associative learning)|go:"GO:0010447"(response to acidic pH)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0036021"(endolysosome lumen)|go:"GO:0042359"(vitamin D metabolic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045177"(apical part of cell)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0097264"(self proteolysis)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1901185"(negative regulation of ERBB signaling pathway)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|interpro:IPR001096(Peptidase C13, legumain)|interpro:IPR043577|mint:Q99538|rcsb pdb:4AW9|rcsb pdb:4AWA|rcsb pdb:4AWB|rcsb pdb:4FGU|rcsb pdb:4N6N|rcsb pdb:4N6O|rcsb pdb:5LU8|rcsb pdb:5LU9|rcsb pdb:5LUA|rcsb pdb:5LUB|reactome:R-HSA-1679131|go:"GO:0040015"(negative regulation of multicellular organism growth)|reactome:R-HSA-196791|reactome:R-HSA-2132295|refseq:XP_005267919.1|refseq:XP_005267920.1|refseq:NP_001008530.1|refseq:NP_005597.3|refseq:XP_016876952.1|refseq:XP_016876953.1|refseq:XP_016876954.1|refseq:XP_016876955.1|refseq:XP_016876956.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377 rogid:W2jPq8/peH5iXt1wmbm8lFnkJwM9606 rigid:4FANyorWpONCi+Bh5Djt5E9Us10 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DF6 uniprotkb:P30273 intact:EBI-21285191|ensemblbacteria:AAO90316 intact:EBI-515289|uniprotkb:Q5VTW4|ensembl:ENSP00000289902 psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name) psi-mi:fcerg_human(display_long)|uniprotkb:IgE Fc receptor subunit gamma(gene name synonym)|uniprotkb:Fc-epsilon RI-gamma(gene name synonym)|uniprotkb:FCER1G(gene name)|psi-mi:FCER1G(display_short)|uniprotkb:Fc receptor gamma-chain(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285266|imex:IM-26899-335 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90316(transcript)|ensemblbacteria:CBU_0781(gene)|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q83DF6 refseq:NP_004097.1|dip:DIP-29514N|ensembl:ENSG00000158869(gene)|ensembl:ENST00000289902(transcript)|go:"GO:0002283"(neutrophil activation involved in immune response)|go:"GO:0002292"(T cell differentiation involved in immune response)|go:"GO:0002431"(Fc receptor mediated stimulatory signaling pathway)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010543"(regulation of platelet activation)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019767"(IgE receptor activity)|go:"GO:0019863"(IgE binding)|go:"GO:0019864"(IgG binding)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031623"(receptor internalization)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032998"(Fc-epsilon receptor I complex)|go:"GO:0038094"(Fc-gamma receptor signaling pathway)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0038156"(interleukin-3-mediated signaling pathway)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0042590"(antigen processing and presentation of exogenous peptide antigen via MHC class I)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|interpro:IPR042340|mint:P30273|reactome:R-HSA-114604|reactome:R-HSA-202733|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|go:"GO:0042742"(defense response to bacterium)|reactome:R-HSA-2871837|reactome:R-HSA-5621480|reactome:R-HSA-6798695|reactome:R-HSA-75892|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response) - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377 rogid:sYW44kyg+jmeUmR9vWSSPdyq4N49606 rigid:r/2hWduE2qCHACX66ES5kQb4+y0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DF6 uniprotkb:O14979 intact:EBI-21285191|ensemblbacteria:AAO90316 intact:EBI-299727|ensembl:ENSP00000295470|ensembl:ENSP00000422040|ensembl:ENSP00000483254|uniprotkb:Q6SPF2|uniprotkb:Q7KZ74|uniprotkb:Q7KZ75|uniprotkb:Q96IM0|uniprotkb:Q96S43 psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name) psi-mi:hnrdl_human(display_long)|uniprotkb:HNRNPDL(gene name)|psi-mi:HNRNPDL(display_short)|uniprotkb:AU-rich element RNA-binding factor(gene name synonym)|uniprotkb:HNRPDL(gene name synonym)|uniprotkb:JKT41-binding protein(gene name synonym)|uniprotkb:JKTBP(gene name synonym)|uniprotkb:Protein laAUF1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285278|imex:IM-26899-549 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90316(transcript)|ensemblbacteria:CBU_0781(gene)|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q83DF6 ensembl:ENSG00000152795(gene)|ensembl:ENST00000295470(transcript)|ensembl:ENST00000502762(transcript)|ensembl:ENST00000621267(transcript)|go:"GO:0003677"(DNA binding)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034847|interpro:IPR035979|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|mint:O14979|go:"GO:0003723"(RNA binding)|reactome:R-HSA-8950505|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008143"("poly(A) binding")|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034046"("poly(G) binding")|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001193929.1|refseq:NP_112740.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377 rogid:oOnEEar8AtKO5G6ldehucaRr4kM9606 rigid:PiMvt6LpSdjN1jkOLNp3EHLUcRE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DF6 uniprotkb:Q92820 intact:EBI-21285191|ensemblbacteria:AAO90316 intact:EBI-3045534|ensembl:ENSP00000260118 psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name) psi-mi:ggh_human(display_long)|uniprotkb:GGH(gene name)|psi-mi:GGH(display_short)|uniprotkb:Conjugase(gene name synonym)|uniprotkb:GH(gene name synonym)|uniprotkb:Gamma-Glu-X carboxypeptidase(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285272|imex:IM-26899-203 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90316(transcript)|ensemblbacteria:CBU_0781(gene)|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q83DF6 ensembl:ENSG00000137563(gene)|ensembl:ENST00000260118(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0008238"(exopeptidase activity)|go:"GO:0008242"(omega peptidase activity)|go:"GO:0010043"(response to zinc ion)|go:"GO:0032868"(response to insulin)|go:"GO:0034722"(gamma-glutamyl-peptidase activity)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0045471"(response to ethanol)|go:"GO:0046900"(tetrahydrofolylpolyglutamate metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070500"(poly-gamma-glutamate metabolic process)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR011697(Peptidase C26)|interpro:IPR015527(Peptidase C26, gamma-glutamyl hydrolase)|interpro:IPR029062|mint:Q92820|rcsb pdb:1L9X|reactome:R-HSA-6798695|refseq:NP_003869.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377 rogid:QjPbv+fLXWnf6gmW2PsXVuyatR49606 rigid:4BxTSWaFx/U43BqJOC771VxcVpo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DF6 uniprotkb:O00505 intact:EBI-21285191|ensemblbacteria:AAO90316 intact:EBI-358297|intact:EBI-28976892|ensembl:ENSP00000261667|uniprotkb:O00191|uniprotkb:O43195|uniprotkb:Q96AA7|uniprotkb:Q5JVM9|intact:EBI-742146|uniprotkb:Q8IYQ9 psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name) psi-mi:ima4_human(display_long)|uniprotkb:KPNA3(gene name)|psi-mi:KPNA3(display_short)|uniprotkb:QIP2(gene name synonym)|uniprotkb:Karyopherin subunit alpha-3(gene name synonym)|uniprotkb:SRP1-gamma(gene name synonym)|uniprotkb:Importin alpha Q2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285284|imex:IM-26899-445 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90316(transcript)|ensemblbacteria:CBU_0781(gene)|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q83DF6 ensembl:ENSG00000102753(gene)|ensembl:ENST00000261667(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0043657"(host cell)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR000225(Armadillo)|refseq:NP_002258.2|ensembl:ENSP00000261667|dip:DIP-27586N|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O00505|reactome:R-HSA-1169408|reactome:R-HSA-168276 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377 rogid:kx/oTYWMYG7dhwJHvr1POLD6FTU9606 rigid:2z6fMftN89WjgDDEDeP7TNJeJaE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DF6 uniprotkb:Q8N0U8 intact:EBI-21285191|ensemblbacteria:AAO90316 intact:EBI-11337915|uniprotkb:E7ETM5|uniprotkb:Q6AHW9|uniprotkb:B4E222|uniprotkb:Q6TEK6|ensembl:ENSP00000353998|ensembl:ENSP00000497394 psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name) psi-mi:vkorl_human(display_long)|uniprotkb:VKORC1L1(gene name)|psi-mi:VKORC1L1(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285378|imex:IM-26899-561 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90316(transcript)|ensemblbacteria:CBU_0781(gene)|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q83DF6 refseq:NP_001271271.1|refseq:NP_775788.2|ensembl:ENSG00000196715(gene)|ensembl:ENST00000360768(transcript)|ensembl:ENST00000648179(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017187"(peptidyl-glutamic acid carboxylation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042373"(vitamin K metabolic process)|go:"GO:0047057"("vitamin-K-epoxide reductase (warfarin-sensitive) activity")|go:"GO:0048038"(quinone binding)|interpro:IPR012932(Vitamin K epoxide reductase)|interpro:IPR038354|interpro:IPR042406|mint:Q8N0U8|reactome:R-HSA-6806664 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377 rogid:0gdoyZTMoqEjTsPOfeUNSlH4M7k9606 rigid:PdfEnjmcGa+uuKy6mjRRG6RbZbw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DF6 uniprotkb:Q8IXX5 intact:EBI-21285191|ensemblbacteria:AAO90316 intact:EBI-2841953|uniprotkb:A8K5W1|uniprotkb:Q6NW15|uniprotkb:Q96E06|ensembl:ENSP00000356211 psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name) psi-mi:t183a_human(display_long)|uniprotkb:TMEM183A(gene name)|psi-mi:TMEM183A(display_short)|uniprotkb:C1orf37(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285372|imex:IM-26899-741 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90316(transcript)|ensemblbacteria:CBU_0781(gene)|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q83DF6 refseq:NP_612400.3|ensembl:ENSG00000163444(gene)|ensembl:ENST00000367242(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR026509|interpro:IPR036047|mint:Q8IXX5 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377 rogid:XNJR0b9RbNBEXSE9ohP+TfVtxzM9606 rigid:CcEnP/Z5j291L7IA0z3ExJlNoQU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DF6 uniprotkb:Q93045 intact:EBI-21285191|ensemblbacteria:AAO90316 intact:EBI-714194|uniprotkb:O14952|uniprotkb:Q6PK68|ensembl:ENSP00000220876|uniprotkb:A8K9M2|uniprotkb:G3V110 psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name) psi-mi:stmn2_human(display_long)|uniprotkb:Superior cervical ganglion-10 protein(gene name synonym)|uniprotkb:STMN2(gene name)|psi-mi:STMN2(display_short)|uniprotkb:SCG10(gene name synonym)|uniprotkb:SCGN10(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285366|imex:IM-26899-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90316(transcript)|ensemblbacteria:CBU_0781(gene)|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q83DF6 ensembl:ENSG00000104435(gene)|ensembl:ENST00000220876(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030426"(growth cone)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0031115"(negative regulation of microtubule polymerization)|go:"GO:0031117"(positive regulation of microtubule depolymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR000956(Stathmin)|interpro:IPR026729|interpro:IPR030514|interpro:IPR036002|mint:Q93045|reactome:R-HSA-9696273|refseq:NP_008960.2|refseq:NP_001186143.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377 rogid:tM3wU+n2JiO1Cp4YeaAOYgBCDDA9606 rigid:64c2KOSD5lONZ083Sf6rF4g0k80 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DF6 uniprotkb:Q1EHB4 intact:EBI-21285191|ensemblbacteria:AAO90316 intact:EBI-21285338|uniprotkb:Q86UC7|ensembl:ENSP00000379326 psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name) psi-mi:sc5ac_human(display_long)|uniprotkb:SLC5A12(gene name)|psi-mi:SLC5A12(display_short)|uniprotkb:SMCT2(gene name synonym)|uniprotkb:Electroneutral sodium monocarboxylate cotransporter(gene name synonym)|uniprotkb:Low-affinity sodium-lactate cotransporter(gene name synonym)|uniprotkb:Solute carrier family 5 member 12(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285360|imex:IM-26899-553 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90316(transcript)|ensemblbacteria:CBU_0781(gene)|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q83DF6 refseq:NP_848593.2|ensembl:ENSG00000148942(gene)|ensembl:ENST00000396005(transcript)|go:"GO:0005343"("organic acid:sodium symporter activity")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0015129"(lactate transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001734(Na+/solute symporter)|interpro:IPR042700|mint:Q1EHB4|reactome:R-HSA-427601 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377 rogid:yIZjC3TzY1kdEvq2qDj/CKb2jVc9606 rigid:jU5GF9N2FxEsIsbk2i+zDc6YCeU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DF6 uniprotkb:Q9NX40 intact:EBI-21285191|ensemblbacteria:AAO90316 intact:EBI-2683029|uniprotkb:C9K030|uniprotkb:Q9BZE8|ensembl:ENSP00000264312|ensembl:ENSP00000370882|ensembl:ENSP00000423002|ensembl:ENSP00000423909|uniprotkb:G8JLN7 psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name) psi-mi:ocad1_human(display_long)|uniprotkb:OCIA(gene name synonym)|uniprotkb:Ovarian carcinoma immunoreactive antigen(gene name synonym)|uniprotkb:OCIAD1(gene name)|psi-mi:OCIAD1(display_short)|uniprotkb:ASRIJ(gene name synonym)|uniprotkb:Ovarian cancer immunoreactive antigen domain containing 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285302|imex:IM-26899-337 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90316(transcript)|ensemblbacteria:CBU_0781(gene)|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q83DF6 refseq:NP_001073309.1|refseq:NP_001073311.2|refseq:NP_001073308.1|refseq:NP_001073310.1|refseq:NP_060300.1|ensembl:ENSG00000109180(gene)|ensembl:ENST00000264312(transcript)|ensembl:ENST00000381473(transcript)|ensembl:ENST00000508293(transcript)|ensembl:ENST00000513391(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006897"(endocytosis)|go:"GO:0016020"(membrane)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR009764(Ovarian carcinoma immunoreactive antigen)|interpro:IPR040187|mint:Q9NX40|refseq:XP_016863818.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377 rogid:e3Ojv8LBlgj056bssUZjEC+MB+Q9606 rigid:4InJ3OPdicngjsNpg7ezCF0MgSA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DF6 uniprotkb:O15173 intact:EBI-21285191|ensemblbacteria:AAO90316 intact:EBI-1050125|uniprotkb:Q569H1|ensembl:ENSP00000296425|ensembl:ENSP00000429301 psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name) psi-mi:pgrc2_human(display_long)|uniprotkb:Progesterone membrane-binding protein(gene name synonym)|uniprotkb:Steroid receptor protein DG6(gene name synonym)|uniprotkb:PGRMC2(gene name)|psi-mi:PGRMC2(display_short)|uniprotkb:DG6(gene name synonym)|uniprotkb:PMBP(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285326|imex:IM-26899-451 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90316(transcript)|ensemblbacteria:CBU_0781(gene)|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q83DF6 refseq:NP_006311.2|ensembl:ENSG00000164040(gene)|ensembl:ENST00000296425(transcript)|ensembl:ENST00000520121(transcript)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0012505"(endomembrane system)|go:"GO:0015232"(heme transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0060612"(adipose tissue development)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400|mint:O15173|reactome:R-HSA-8980692|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377 rogid:y8PU98eUcxnJLxobBcFL40xaprw9606 rigid:7b4z6nCmq84hE/+ZrGPxKKQl9mM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DF6 uniprotkb:Q8IYB4 intact:EBI-21285191|ensemblbacteria:AAO90316 intact:EBI-15749355|intact:EBI-28986271|ensembl:ENSP00000419975|uniprotkb:B7Z2A5|uniprotkb:B7Z305|uniprotkb:B7Z318|uniprotkb:B7Z5Z5|uniprotkb:B7Z8P2|uniprotkb:E7EUV8|uniprotkb:E7EUZ0|uniprotkb:E9PEC1|uniprotkb:E9PH97|uniprotkb:Q9NQD1|uniprotkb:Q9P2U3|uniprotkb:Q9P2U4 psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name) psi-mi:pex5r_human(display_long)|uniprotkb:PEX5L(gene name)|psi-mi:PEX5L(display_short)|uniprotkb:PEX5R(gene name synonym)|uniprotkb:PXR2(gene name synonym)|uniprotkb:PEX2-related protein(gene name synonym)|uniprotkb:PEX5-like protein(gene name synonym)|uniprotkb:Peroxin-5-related protein(gene name synonym)|uniprotkb:Peroxisome biogenesis factor 5-like(gene name synonym)|uniprotkb:Tetratricopeptide repeat-containing Rab8b-interacting protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285320|imex:IM-26899-221 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90316(transcript)|ensemblbacteria:CBU_0781(gene)|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q83DF6 ensembl:ENSG00000114757(gene)|ensembl:ENST00000467460(transcript)|go:"GO:0000268"(peroxisome targeting sequence binding)|go:"GO:0005052"(peroxisome matrix targeting signal-1 binding)|go:"GO:0005221"(intracellular cyclic nucleotide activated cation channel activity)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR024111|interpro:IPR024112|mint:Q8IYB4|ensembl:ENST00000263962|ensembl:ENSP00000263962|ensembl:ENST00000392649|ensembl:ENSP00000376420|ensembl:ENST00000464614|ensembl:ENSP00000417270|ensembl:ENST00000465751|ensembl:ENSP00000419348|ensembl:ENSP00000419975|ensembl:ENST00000468741|ensembl:ENSP00000418665|ensembl:ENST00000472994|ensembl:ENSP00000418054|ensembl:ENST00000476138|ensembl:ENSP00000420555|ensembl:ENST00000485199|ensembl:ENSP00000418440|refseq:NP_001243679.1|refseq:NP_001243680.1|refseq:NP_001243681.1|refseq:NP_001243682.1|refseq:NP_001243683.1|refseq:NP_001243684.1|refseq:NP_001243685.1|refseq:NP_057643.1|refseq:XP_011511189.1|refseq:XP_011511193.1|refseq:XP_011511194.1|refseq:XP_016862095.1|refseq:XP_016862096.1|refseq:XP_016862097.1|refseq:XP_016862098.1|refseq:XP_016862099.1|refseq:XP_016862100.1|dip:DIP-58547N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377 rogid:ToCqEYoApcFXqlRyDgfd/tchKRM9606 rigid:xV1OgKjvlZl+Mb4RgPTKLoRNpyw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DF6 uniprotkb:Q9UKK3 intact:EBI-21285191|ensemblbacteria:AAO90316 intact:EBI-2623021|uniprotkb:Q5QNZ9|uniprotkb:O75903|uniprotkb:Q14682|uniprotkb:Q9H1M6|ensembl:ENSP00000371419 psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name) psi-mi:parp4_human(display_long)|uniprotkb:ADPRTL1(gene name synonym)|uniprotkb:KIAA0177(gene name synonym)|uniprotkb:PARPL(gene name synonym)|uniprotkb:193 kDa vault protein(gene name synonym)|uniprotkb:PARP-related/IalphaI-related H5/proline-rich(gene name synonym)|uniprotkb:"Vault poly(ADP-ribose) polymerase"(gene name synonym)|uniprotkb:PARP4(gene name)|psi-mi:PARP4(display_short)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 4(gene name synonym)|uniprotkb:Poly [ADP-ribose] polymerase 4(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285314|imex:IM-26899-449 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90316(transcript)|ensemblbacteria:CBU_0781(gene)|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q83DF6 refseq:XP_011533234.1|refseq:NP_006428.2|ensembl:ENSG00000102699(gene)|ensembl:ENST00000381989(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006281"(DNA repair)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008219"(cell death)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0042493"|go:"GO:0051972"(regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140289"(protein mono-ADP-ribosylation)|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001357(BRCT)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR013694(Vault protein inter-alpha-trypsin)|interpro:IPR031273|interpro:IPR036420|interpro:IPR036465|interpro:IPR036616|mint:Q9UKK3|reactome:R-HSA-197264|reactome:R-HSA-9683610|reactome:R-HSA-9694631 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377 rogid:d1n+oei4ZSmqUnvJzMe6RLq2XOc9606 rigid:55uEzh09onA0Q2aNoJTWMYBOdYg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DF6 uniprotkb:P00439 intact:EBI-21285191|ensemblbacteria:AAO90316 intact:EBI-2861444|uniprotkb:Q16717|uniprotkb:Q8TC14|ensembl:ENSP00000448059 psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name) psi-mi:ph4h_human(display_long)|uniprotkb:PAH(gene name)|psi-mi:PAH(display_short)|uniprotkb:Phe-4-monooxygenase(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285308|imex:IM-26899-339 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90316(transcript)|ensemblbacteria:CBU_0781(gene)|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q83DF6 refseq:NP_000268.1|dip:DIP-58927N|ensembl:ENSG00000171759(gene)|ensembl:ENST00000553106(transcript)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0006559"(L-phenylalanine catabolic process)|go:"GO:0006571"(tyrosine biosynthetic process)|rcsb pdb:1DMW|rcsb pdb:1J8T|rcsb pdb:1J8U|rcsb pdb:1KW0|rcsb pdb:1LRM|rcsb pdb:1MMK|go:"GO:0008652"(cellular amino acid biosynthetic process)|rcsb pdb:1MMT|rcsb pdb:1PAH|rcsb pdb:1TDW|rcsb pdb:1TG2|rcsb pdb:2PAH|rcsb pdb:3PAH|rcsb pdb:4ANP|rcsb pdb:4PAH|rcsb pdb:5FII|rcsb pdb:5PAH|rcsb pdb:6HPO|rcsb pdb:6HYC|rcsb pdb:6N1K|rcsb pdb:6PAH|reactome:R-HSA-2160456|reactome:R-HSA-8964208|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042423"(catecholamine biosynthetic process)|interpro:IPR001273(Aromatic amino acid hydroxylase)|interpro:IPR002912(Amino acid-binding ACT)|interpro:IPR005961(Phenylalanine-4-hydroxylase, tetrameric form)|interpro:IPR018301|interpro:IPR019773|interpro:IPR019774|interpro:IPR036329|interpro:IPR036951|interpro:IPR041912|mint:P00439 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377 rogid:byO1PdD6RTWtUZOt5A9/N/Gl4Do9606 rigid:Dc5LJB5XIrKoCFt7aRoRAF4NFi4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DF6 uniprotkb:P48382 intact:EBI-21285191|ensemblbacteria:AAO90316 intact:EBI-923266|uniprotkb:Q5VWC3|uniprotkb:D3DV19|uniprotkb:B7Z848|uniprotkb:E9PFU4|ensembl:ENSP00000290524|ensembl:ENSP00000357864|ensembl:ENSP00000389130 psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name) psi-mi:rfx5_human(display_long)|uniprotkb:RFX5(gene name)|psi-mi:RFX5(display_short)|uniprotkb:Regulatory factor X 5(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285332|imex:IM-26899-551 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90316(transcript)|ensemblbacteria:CBU_0781(gene)|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q83DF6 refseq:NP_000440.1|refseq:NP_001020774.1|refseq:XP_005245462.1|refseq:XP_005245463.1|refseq:XP_011508149.1|refseq:XP_011508150.1|refseq:XP_011508151.1|refseq:XP_011508152.1|ensembl:ENSG00000143390(gene)|ensembl:ENST00000290524(transcript)|ensembl:ENST00000368870(transcript)|ensembl:ENST00000452671(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR029298|interpro:IPR033486|interpro:IPR036388|interpro:IPR036390|interpro:IPR039779|interpro:IPR040889|mint:P48382|rcsb pdb:2KW3|rcsb pdb:3V30|go:"GO:1990837"(sequence-specific double-stranded DNA binding) - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377 rogid:kElLakR+ct4K8Mw6q91im3K8Zh89606 rigid:lUYBOwaqdRdQK+vgnz4NRX25mTo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DF6 uniprotkb:Q9NR11 intact:EBI-21285191|ensemblbacteria:AAO90316 intact:EBI-3916142|uniprotkb:Q9P0J4|uniprotkb:Q9BZD8|uniprotkb:Q658J3 psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name) psi-mi:zn302_human(display_long)|uniprotkb:ZNF302(gene name)|psi-mi:ZNF302(display_short)|uniprotkb:ZNF135L(gene name synonym)|uniprotkb:ZNF140L(gene name synonym)|uniprotkb:ZNF327(gene name synonym)|uniprotkb:Zinc finger protein 135-like(gene name synonym)|uniprotkb:Zinc finger protein 140-like(gene name synonym)|uniprotkb:Zinc finger protein 327(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285408|imex:IM-26899-743 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90316(transcript)|ensemblbacteria:CBU_0781(gene)|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q83DF6 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|reactome:R-HSA-212436|interpro:IPR036051|interpro:IPR036236|refseq:NP_001012320.1|refseq:NP_060913.2|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001276116.1|refseq:NP_001276117.1|refseq:NP_001276118.1|refseq:NP_001276110.1|refseq:NP_001276111.1|refseq:NP_001276119.1|refseq:NP_001276112.1|refseq:NP_001276113.1|refseq:NP_001276120.1|refseq:NP_001276114.1|refseq:NP_001276115.1|refseq:NP_001276121.1|refseq:NP_061145.2|mint:Q9NR11 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377 rogid:FihdHXyOLfG5HUdPhyThDDsJHkA9606 rigid:mdO1rgTGCnO19QRRZxdlwyiNfqc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DF6 uniprotkb:Q9H6R6 intact:EBI-21285191|ensemblbacteria:AAO90316 intact:EBI-725179|uniprotkb:Q53G45|uniprotkb:Q96IV7|uniprotkb:Q9H605|uniprotkb:D3DRB6|ensembl:ENSP00000358413|ensembl:ENSP00000507009|ensembl:ENSP00000507661 psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name) psi-mi:zdhc6_human(display_long)|uniprotkb:Zinc finger DHHC domain-containing protein 6(gene name synonym)|uniprotkb:Zinc finger protein 376(gene name synonym)|uniprotkb:Transmembrane protein H4(gene name synonym)|uniprotkb:ZDHHC6(gene name)|psi-mi:ZDHHC6(display_short)|uniprotkb:ZNF376(gene name synonym)|uniprotkb:Stearoyltransferase ZDHHC6(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285402|imex:IM-26899-225 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90316(transcript)|ensemblbacteria:CBU_0781(gene)|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q83DF6 refseq:NP_071939.1|refseq:NP_001290063.1|refseq:XP_005270108.1|refseq:XP_006718011.1|refseq:XP_016872050.1|refseq:XP_016872051.1|refseq:XP_016872052.1|ensembl:ENSG00000023041(gene)|ensembl:ENST00000369405(transcript)|ensembl:ENST00000683895(transcript)|ensembl:ENST00000684507(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0010636"(positive regulation of mitochondrial fusion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0043543"(protein acylation)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001452(Src homology-3)|interpro:IPR001594(Zinc finger, DHHC-type)|go:"GO:0016747"(acyltransferase activity, transferring groups other than amino-acyl groups)|mint:Q9H6R6 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377 rogid:GLUdVccZzQNxx/i8l0yMS/p6GXo9606 rigid:zhv3Cf1fIoRGvkk4ADu7KV/29vw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DF6 uniprotkb:O75132 intact:EBI-21285191|ensemblbacteria:AAO90316 intact:EBI-2860059|uniprotkb:B2RZH1|uniprotkb:Q9UGG8|uniprotkb:Q1ECU0|ensembl:ENSP00000216268 psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name) psi-mi:zbed4_human(display_long)|uniprotkb:ZBED4(gene name)|psi-mi:ZBED4(display_short)|uniprotkb:KIAA0637(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285384|imex:IM-26899-645 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90316(transcript)|ensemblbacteria:CBU_0781(gene)|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q83DF6 refseq:NP_055653.2|ensembl:ENSG00000100426(gene)|ensembl:ENST00000216268(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR003656(Zinc finger, BED-type predicted)|interpro:IPR008906(HAT dimerisation)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036236|mint:O75132 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377 rogid:T1pqiOcpLeOA25QudngK1xk+xaA9606 rigid:+p+H+wxZpfDuSlGf8rxwuQP18Ss false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DF6 uniprotkb:Q8WU90 intact:EBI-21285191|ensemblbacteria:AAO90316 intact:EBI-1042636|uniprotkb:Q5QTQ4|uniprotkb:Q8WZ06|uniprotkb:Q9NUZ3|uniprotkb:Q9P079|uniprotkb:Q9NZ37|uniprotkb:B4DMW2|uniprotkb:D3DPG7|ensembl:ENSP00000338788 psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name) psi-mi:zc3hf_human(display_long)|uniprotkb:ZC3H15(gene name)|psi-mi:ZC3H15(display_short)|uniprotkb:DFRP1(gene name synonym)|uniprotkb:LEREPO4(gene name synonym)|uniprotkb:DRG family-regulatory protein 1(gene name synonym)|uniprotkb:Likely ortholog of mouse immediate early response erythropoietin 4(gene name synonym)|uniprotkb:HSPC303(orf name)|uniprotkb:HT010(orf name)|uniprotkb:MSTP012(orf name)|uniprotkb:PP730(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285390|imex:IM-26899-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90316(transcript)|ensemblbacteria:CBU_0781(gene)|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q83DF6 refseq:NP_060941.2|ensembl:ENSG00000065548(gene)|ensembl:ENST00000337859(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR032378|interpro:IPR036855|interpro:IPR041367|mint:Q8WU90 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377 rogid:MrcssHMHDoQKqsIXdhfMWOnHlBY9606 rigid:tMxZdX80/zCXH89j4y4pBhxo2gs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DF6 uniprotkb:Q8N5P1 intact:EBI-21285191|ensemblbacteria:AAO90316 intact:EBI-5280267|uniprotkb:Q9BZ75|ensembl:ENSP00000272570|ensembl:ENSP00000386488 psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name) psi-mi:zc3h8_human(display_long)|uniprotkb:ZC3H8(gene name)|psi-mi:ZC3H8(display_short)|uniprotkb:ZC3HDC8(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285396|imex:IM-26899-223 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90316(transcript)|ensemblbacteria:CBU_0781(gene)|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q83DF6 refseq:NP_115883.2|go:"GO:0035363"(histone locus body)|go:"GO:0042795"(snRNA transcription by RNA polymerase II)|go:"GO:0042796"(snRNA transcription by RNA polymerase III)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|mint:Q8N5P1|reactome:R-HSA-6807505|ensembl:ENSG00000144161(gene)|ensembl:ENST00000272570(transcript)|ensembl:ENST00000409573(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0033085"(negative regulation of T cell differentiation in thymus)|go:"GO:0035327" - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377 rogid:ltW8I583M/LV8XKPzLRvojXc+AA9606 rigid:knQPKVk2a+q+j5Q+5mQSv5lRqzg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DE4 uniprotkb:Q8NAN2 intact:EBI-21285423|ensemblbacteria:AAO90328 intact:EBI-13943438|uniprotkb:Q6MZG0|ensembl:ENSP00000359827|ensembl:ENSP00000495281 psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name) psi-mi:miga1_human(display_long)|uniprotkb:MIGA1(gene name)|psi-mi:MIGA1(display_short)|uniprotkb:FAM73A(gene name synonym)|uniprotkb:Protein FAM73A(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285447|imex:IM-26899-341 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90328(transcript)|ensemblbacteria:CBU_0794(gene)|refseq:NP_819814.1|refseq:WP_010957806.1|mint:Q83DE4 refseq:NP_001257313.1|refseq:NP_940951.1|ensembl:ENSG00000180488(gene)|ensembl:ENST00000370791(transcript)|ensembl:ENST00000643143(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR019392|mint:Q8NAN2|reactome:R-HSA-1483166 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:XVA7R483yYdpYkhCnAqOzU8u000227377 rogid:ZIDtgENE8en73tFnADIVIal9wcg9606 rigid:JL31FQj0DDusidun8UNouSNBd0o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DE4 uniprotkb:Q9Y3M2 intact:EBI-21285423|ensemblbacteria:AAO90328 intact:EBI-947308|uniprotkb:Q66GT6|uniprotkb:Q9UIK9|uniprotkb:B2R4S2|ensembl:ENSP00000216029|ensembl:ENSP00000380026 psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name) psi-mi:cby1_human(display_long)|uniprotkb:CBY1(gene name)|psi-mi:CBY1(display_short)|uniprotkb:C22orf2(gene name synonym)|uniprotkb:CBY(gene name synonym)|uniprotkb:HRIHFB2025(orf name)|uniprotkb:ARB1(gene name synonym)|uniprotkb:PGEA1(gene name synonym)|uniprotkb:PKD2 interactor, Golgi and endoplasmic reticulum-associated 1(gene name synonym)|uniprotkb:PIGEA-14(gene name synonym)|uniprotkb:Cytosolic leucine-rich protein(gene name synonym)|uniprotkb:ARPP-binding protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285441|imex:IM-26899-563 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90328(transcript)|ensemblbacteria:CBU_0794(gene)|refseq:NP_819814.1|refseq:WP_010957806.1|mint:Q83DE4 refseq:NP_056188.1|refseq:NP_001002880.2|dip:DIP-29651N|ensembl:ENSG00000100211(gene)|ensembl:ENST00000216029(transcript)|ensembl:ENST00000396811(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008104"(protein localization)|go:"GO:0016607"(nuclear speck)|go:"GO:0030030"(cell projection organization)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055007"(cardiac muscle cell differentiation)|interpro:IPR028118|mint:Q9Y3M2|rcsb pdb:4WRQ|reactome:R-HSA-3769402 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:XVA7R483yYdpYkhCnAqOzU8u000227377 rogid:RqvyVBe3nAEf0bYnToiVsM5hLhc9606 rigid:vFnPTlXRna1ZE9gghKtkET9gbDk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DF6 uniprotkb:O75123 intact:EBI-21285191|ensemblbacteria:AAO90316 intact:EBI-18560922|uniprotkb:A4FU80|uniprotkb:B4DGP3|uniprotkb:E7ENV5|ensembl:ENSP00000445979|ensembl:ENSP00000487869 psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name) psi-mi:zn623_human(display_long)|uniprotkb:ZNF623(gene name)|psi-mi:ZNF623(display_short)|uniprotkb:KIAA0628(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285417|imex:IM-26899-745 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90316(transcript)|ensemblbacteria:CBU_0781(gene)|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q83DF6 refseq:NP_001075949.1|refseq:NP_001248772.1|refseq:NP_055604.3|ensembl:ENSG00000183309(gene)|ensembl:ENSG00000276340(gene)|ensembl:ENST00000501748(transcript)|ensembl:ENST00000633071(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:O75123|refseq:XP_006716771.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2020/03/03 rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377 rogid:ZPDs42UpkZdzLtqeMEZie5uUhdA9606 rigid:h4LwyiGdqoFQi0GlNn6buSQ8ZDo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DE4 uniprotkb:Q15389 intact:EBI-21285423|ensemblbacteria:AAO90328 intact:EBI-2922365|ensembl:ENSP00000428340|uniprotkb:Q5HYA0 psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name) psi-mi:angp1_human(display_long)|uniprotkb:ANGPT1(gene name)|psi-mi:ANGPT1(display_short)|uniprotkb:KIAA0003(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285429|imex:IM-26899-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90328(transcript)|ensemblbacteria:CBU_0794(gene)|refseq:NP_819814.1|refseq:WP_010957806.1|mint:Q83DE4 ensembl:ENSG00000154188(gene)|ensembl:ENST00000517746(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0002719"(negative regulation of cytokine production involved in immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007171"(activation of transmembrane receptor protein tyrosine kinase activity)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014842"(regulation of skeletal muscle satellite cell proliferation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030210"(heparin biosynthetic process)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045121"(membrane raft)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048014"(Tie signaling pathway)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0072012"(glomerulus vasculature development)|go:"GO:1905605"(positive regulation of blood-brain barrier permeability)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2000446"(regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR028843|interpro:IPR036056|mint:Q15389|rcsb pdb:4EPU|rcsb pdb:4JYO|rcsb pdb:4K0V|reactome:R-HSA-210993|reactome:R-HSA-5673001|go:"GO:0031398"(positive regulation of protein ubiquitination)|refseq:NP_001137.2|refseq:NP_001186788.1|refseq:NP_001300980.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:XVA7R483yYdpYkhCnAqOzU8u000227377 rogid:UQX0FGhzdmPbYOvuvmXxBdkEgjk9606 rigid:ynj5TnB5OoYuzNGp5ngOZZw0310 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DE4 uniprotkb:Q13137 intact:EBI-21285423|ensemblbacteria:AAO90328 intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5 psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name) psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285435|imex:IM-26899-453 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90328(transcript)|ensemblbacteria:CBU_0794(gene)|refseq:NP_819814.1|refseq:WP_010957806.1|mint:Q83DE4 refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N - - crc64:609B121DA1A9DCB8 figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:XVA7R483yYdpYkhCnAqOzU8u000227377 rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606 rigid:0Wk3ugIC7O1MWcWd1gq46Y8wqGo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DE4 uniprotkb:Q9NUP9 intact:EBI-21285423|ensemblbacteria:AAO90328 intact:EBI-1171517|ensembl:ENSP00000278193 psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name) psi-mi:lin7c_human(display_long)|uniprotkb:Mammalian lin-seven protein 3(gene name synonym)|uniprotkb:Vertebrate lin-7 homolog 3(gene name synonym)|uniprotkb:LIN7C(gene name)|psi-mi:LIN7C(display_short)|uniprotkb:MALS3(gene name synonym)|uniprotkb:VELI3(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285459|imex:IM-26899-647 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90328(transcript)|ensemblbacteria:CBU_0794(gene)|refseq:NP_819814.1|refseq:WP_010957806.1|mint:Q83DE4 refseq:NP_060832.1|ensembl:ENSG00000148943(gene)|ensembl:ENST00000278193(transcript)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006887"(exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0098793"(presynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR017365(Lin-7 homologue)|interpro:IPR036034|interpro:IPR036892|mint:Q9NUP9|rcsb pdb:3LRA|reactome:R-HSA-212676|reactome:R-HSA-6794361|reactome:R-HSA-9609736 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:XVA7R483yYdpYkhCnAqOzU8u000227377 rogid:F2rasaJ64Olc9qScN79LJRqsUEE9606 rigid:hSTd/VycxbFX5I0w0139tjMI0AU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DE4 uniprotkb:Q96PY5 intact:EBI-21285423|ensemblbacteria:AAO90328 intact:EBI-3438448|uniprotkb:Q8N3E0|uniprotkb:Q4ZG52|uniprotkb:Q14CC9|uniprotkb:B2RZH5 psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name) psi-mi:fmnl2_human(display_long)|uniprotkb:FMNL2(gene name)|psi-mi:FMNL2(display_short)|uniprotkb:FHOD2(gene name synonym)|uniprotkb:KIAA1902(gene name synonym)|uniprotkb:Formin homology 2 domain-containing protein 2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285453|imex:IM-26899-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90328(transcript)|ensemblbacteria:CBU_0794(gene)|refseq:NP_819814.1|refseq:WP_010957806.1|mint:Q83DE4 interpro:IPR043592|refseq:NP_443137.2|interpro:IPR016024(Armadillo-type fold)|interpro:IPR014767(Diaphanous autoregulatory)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR014768(GTPase-binding/formin homology 3)|mint:Q96PY5|interpro:IPR027656|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|rcsb pdb:4YC7|reactome:R-HSA-5663220|reactome:R-HSA-9013106|reactome:R-HSA-9013148|interpro:IPR042201|interpro:IPR011989(Armadillo-like helical) - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:XVA7R483yYdpYkhCnAqOzU8u000227377 rogid:My1jgXVf11giGBKinod/inR4HH49606 rigid:BLjntn/o5sh8JBC8fxURcuEdHw0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DE4 uniprotkb:Q03112 intact:EBI-21285423|ensemblbacteria:AAO90328 intact:EBI-1384862|uniprotkb:Q16122|uniprotkb:Q99917|uniprotkb:C9JAK0|uniprotkb:Q5HYI1|uniprotkb:Q6MZS6|uniprotkb:Q8NEI5|uniprotkb:A1L4F3|uniprotkb:A8KA00|uniprotkb:B7Z8W7|uniprotkb:B7ZLQ3|uniprotkb:B7ZLQ4|uniprotkb:D3DNP7|ensembl:ENSP00000417899|intact:EBI-8475192|intact:MINT-8417693|uniprotkb:E7EQ57|uniprotkb:Q13465|uniprotkb:Q13466|uniprotkb:Q6FH90 psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name) psi-mi:mecom_human(display_long)|uniprotkb:MECOM(gene name)|psi-mi:MECOM(display_short)|uniprotkb:EVI1(gene name synonym)|uniprotkb:Ecotropic virus integration site 1 protein homolog(gene name synonym)|uniprotkb:MDS1(gene name synonym)|uniprotkb:Myelodysplasia syndrome 1 protein(gene name synonym)|uniprotkb:Myelodysplasia syndrome-associated protein 1(gene name synonym)|uniprotkb:MDS1 and EVI1 complex locus protein(gene name synonym)|uniprotkb:PRDM3(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285465|imex:IM-26899-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90328(transcript)|ensemblbacteria:CBU_0794(gene)|refseq:NP_819814.1|refseq:WP_010957806.1|mint:Q83DE4 refseq:NP_001098547.3|refseq:NP_001098548.2|refseq:NP_001157471.1|refseq:NP_001157472.1|refseq:NP_001192123.1|refseq:NP_004982.2|refseq:NP_005232.2|ensembl:ENSG00000085276(gene)|ensembl:ENST00000494292(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0071425"(hematopoietic stem cell proliferation)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR044411|mint:Q03112|rcsb pdb:6BW3|reactome:R-HSA-3214841|reactome:R-HSA-8943724|interpro:IPR036236|refseq:XP_016861363.1|refseq:XP_016861364.1|refseq:XP_016861365.1|refseq:XP_005247278.1|refseq:XP_005247280.1|refseq:XP_005247272.1|dip:DIP-38639N|refseq:XP_005247276.1|refseq:XP_005247277.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:XVA7R483yYdpYkhCnAqOzU8u000227377 rogid:MAlEIuVZS4+BNoy50jejv2O30WA9606 rigid:eNQSCi1Sr4jE3nm1UCUlkgjxfkQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DE4 uniprotkb:O14786 intact:EBI-21285423|ensemblbacteria:AAO90328 intact:EBI-1187100|uniprotkb:O60461|uniprotkb:Q96IH5|uniprotkb:Q5T7F2|uniprotkb:Q5T7F3|uniprotkb:B0LPG9|uniprotkb:Q86T59|uniprotkb:Q5T7F1|uniprotkb:Q96I90|ensembl:ENSP00000265371|ensembl:ENSP00000364001 psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name) psi-mi:nrp1_human(display_long)|uniprotkb:Vascular endothelial cell growth factor 165 receptor(gene name synonym)|uniprotkb:NRP1(gene name)|psi-mi:NRP1(display_short)|uniprotkb:NRP(gene name synonym)|uniprotkb:VEGF165R(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285471|imex:IM-26899-111 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90328(transcript)|ensemblbacteria:CBU_0794(gene)|refseq:NP_819814.1|refseq:WP_010957806.1|mint:Q83DE4 refseq:NP_001019800.1|refseq:NP_001019799.1|refseq:NP_003864.4|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR000859(CUB)|interpro:IPR000998(MAM)|interpro:IPR008979(Galactose-binding like)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR014648(Neuropilin)|interpro:IPR022579|interpro:IPR027146|interpro:IPR035914|mint:O14786|rcsb pdb:1KEX|rcsb pdb:2QQI|rcsb pdb:2QQM|rcsb pdb:2QQN|rcsb pdb:3I97|rcsb pdb:4DEQ|rcsb pdb:4RN5|rcsb pdb:5C7G|rcsb pdb:5IJR|rcsb pdb:5IYY|rcsb pdb:5J1X|rcsb pdb:5JGI|rcsb pdb:5JGQ|rcsb pdb:5JHK|rcsb pdb:5L73|rcsb pdb:6FMC|rcsb pdb:6FMF|rcsb pdb:6TKK|rcsb pdb:7JJC|reactome:R-HSA-194306|reactome:R-HSA-376176|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-399956|reactome:R-HSA-445144|reactome:R-HSA-447041|refseq:NP_001316997.1|ensembl:ENSG00000099250(gene)|ensembl:ENST00000265371(transcript)|ensembl:ENST00000374867(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001764"(neuron migration)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0002116"(semaphorin receptor complex)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0005021"(vascular endothelial growth factor-activated receptor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007165"(signal transduction)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0008201"(heparin binding)|go:"GO:0009611"(response to wounding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0015026"(coreceptor activity)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019838"(growth factor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021637"(trigeminal nerve structural organization)|go:"GO:0021649"(vestibulocochlear nerve structural organization)|go:"GO:0021675"(nerve development)|go:"GO:0021785"(branchiomotor neuron axon guidance)|go:"GO:0021828"(gonadotrophin-releasing hormone neuronal migration to the hypothalamus)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035767"(endothelial cell chemotaxis)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036486"(ventral trunk neural crest cell migration)|go:"GO:0038085"(vascular endothelial growth factor binding)|go:"GO:0038189"(neuropilin signaling pathway)|go:"GO:0038190"(VEGF-activated neuropilin signaling pathway)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048842"(positive regulation of axon extension involved in axon guidance)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0048846"(axon extension involved in axon guidance)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060301"(positive regulation of cytokine activity)|go:"GO:0060385"(axonogenesis involved in innervation)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0060666"(dichotomous subdivision of terminal units involved in salivary gland branching)|go:"GO:0060978"(angiogenesis involved in coronary vascular morphogenesis)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:0061299"(retina vasculature morphogenesis in camera-type eye)|go:"GO:0061441"(renal artery morphogenesis)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0061549"(sympathetic ganglion development)|go:"GO:0061551"(trigeminal ganglion development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090259"(regulation of retinal ganglion cell axon guidance)|go:"GO:0097102"(endothelial tip cell fate specification)|go:"GO:0097374"(sensory neuron axon guidance)|go:"GO:0097443"(sorting endosome)|go:"GO:0097475"(motor neuron migration)|go:"GO:0097490"(sympathetic neuron projection extension)|go:"GO:0097491"(sympathetic neuron projection guidance)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099173"(postsynapse organization)|go:"GO:0150018"(basal dendrite development)|go:"GO:0150020"(basal dendrite arborization)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901166"(neural crest cell migration involved in autonomic nervous system development)|go:"GO:1901998"(toxin transport)|go:"GO:1902285"(semaphorin-plexin signaling pathway involved in neuron projection guidance)|go:"GO:1902287"(semaphorin-plexin signaling pathway involved in axon guidance)|go:"GO:1902336"(positive regulation of retinal ganglion cell axon guidance)|go:"GO:1902378"(VEGF-activated neuropilin signaling pathway involved in axon guidance)|go:"GO:1902946"(protein localization to early endosome)|go:"GO:1903375"(facioacoustic ganglion development)|go:"GO:1904835"(dorsal root ganglion morphogenesis)|go:"GO:1905040"(otic placode development)|dip:DIP-5743N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:XVA7R483yYdpYkhCnAqOzU8u000227377 rogid:q8i8R/AetWNGkscqBWAJPHhmF+E9606 rigid:Qnf4i42DM2iiAqeBpWtjFSJK3Bw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DE4 uniprotkb:Q96SU4 intact:EBI-21285423|ensemblbacteria:AAO90328 intact:EBI-2511368|ensembl:ENSP00000407168|uniprotkb:Q6IA67|uniprotkb:Q9H9X2|uniprotkb:Q96SK4|uniprotkb:B1AKJ8|uniprotkb:Q5TFC0|uniprotkb:Q8NB17|uniprotkb:Q8TAS8|uniprotkb:D3DQ31|uniprotkb:B3KPQ4|uniprotkb:Q86YQ3 psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name) psi-mi:osbl9_human(display_long)|uniprotkb:OSBPL9(gene name)|psi-mi:OSBPL9(display_short)|uniprotkb:ORP9(gene name synonym)|uniprotkb:OSBP4(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285477|imex:IM-26899-747 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90328(transcript)|ensemblbacteria:CBU_0794(gene)|refseq:NP_819814.1|refseq:WP_010957806.1|mint:Q83DE4 ensembl:ENSG00000117859(gene)|ensembl:ENST00000428468(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032934"(sterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|mint:Q96SU4|reactome:R-HSA-192105|refseq:XP_011538905.1|refseq:XP_011538906.1|refseq:NP_078862.4|refseq:NP_683702.1|refseq:NP_683703.1|refseq:NP_683705.1|refseq:NP_683706.3|refseq:NP_683704.2|refseq:NP_683707.3|refseq:XP_006710386.1|refseq:XP_006710387.1|refseq:XP_006710388.1|refseq:XP_006710389.1|refseq:NP_001317509.1|refseq:XP_016855708.1|refseq:XP_016855709.1|refseq:XP_016855710.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:XVA7R483yYdpYkhCnAqOzU8u000227377 rogid:2XLQ0JD4BEKGoyiwd/63YTmyVlE9606 rigid:BSEP4+hnDpDexj1yX/jPJ6BXK5M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DE4 uniprotkb:Q9H2B2 intact:EBI-21285423|ensemblbacteria:AAO90328 intact:EBI-751132|uniprotkb:Q9P2K4|uniprotkb:B4DEU3|ensembl:ENSP00000255224 psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name) psi-mi:syt4_human(display_long)|uniprotkb:Synaptotagmin IV(gene name synonym)|uniprotkb:SYT4(gene name)|psi-mi:SYT4(display_short)|uniprotkb:KIAA1342(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285507|imex:IM-26899-229 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90328(transcript)|ensemblbacteria:CBU_0794(gene)|refseq:NP_819814.1|refseq:WP_010957806.1|mint:Q83DE4 refseq:NP_065834.1|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017158"(regulation of calcium ion-dependent exocytosis)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030276"(clathrin binding)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030348"(syntaxin-3 binding)|go:"GO:0030424"(axon)|go:"GO:0031339"(negative regulation of vesicle fusion)|go:"GO:0032127"(dense core granule membrane)|go:"GO:0033604"(negative regulation of catecholamine secretion)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045202"(synapse)|go:"GO:0045955"(negative regulation of calcium ion-dependent exocytosis)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0046929"(negative regulation of neurotransmitter secretion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061782"(vesicle fusion with vesicle)|go:"GO:0061792"(secretory granule maturation)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0097449"(astrocyte projection)|go:"GO:0098675"(intrinsic component of neuronal dense core vesicle membrane)|go:"GO:0098992"(neuronal dense core vesicle)|go:"GO:0099519"(dense core granule cytoskeletal transport)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1905414"(negative regulation of dense core granule exocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001565(Synaptotagmin)|interpro:IPR028683|interpro:IPR035892|mint:Q9H2B2|rcsb pdb:1UGK|ensembl:ENSG00000132872(gene)|ensembl:ENST00000255224(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007420"(brain development)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0016192"(vesicle-mediated transport) - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:XVA7R483yYdpYkhCnAqOzU8u000227377 rogid:YPZsSWN/mncWeC+vGJ2YYWbHZfU9606 rigid:2Tq+DshoPtDb1Inn2+968xrOuIE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NHS9 uniprotkb:Q83DE4 intact:EBI-7067260|ensembl:ENSP00000380354|ensembl:ENSP00000459329|ensembl:ENSP00000459580|ensembl:ENSP00000460187|intact:MINT-8201601|uniprotkb:D3DTI9|uniprotkb:J3KN63|uniprotkb:Q96JT4|uniprotkb:Q969H3|uniprotkb:B4DXB1 intact:EBI-21285423|ensemblbacteria:AAO90328 psi-mi:spt22_human(display_long)|uniprotkb:SPATA22(gene name)|psi-mi:SPATA22(display_short)|uniprotkb:Testis development protein NYD-SP20(gene name synonym) psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285501|imex:IM-26899-749 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308265.1|refseq:NP_001308266.1|ensembl:ENSG00000141255(gene)|ensembl:ENST00000397168(transcript)|ensembl:ENST00000572969(transcript)|ensembl:ENST00000573128(transcript)|ensembl:ENST00000575375(transcript)|go:"GO:0000711"(meiotic DNA repair synthesis)|go:"GO:0005694"(chromosome)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007276"(gamete generation)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060631"(regulation of meiosis I)|interpro:IPR033536|mint:Q8NHS9|refseq:NP_001164167.1|refseq:NP_001164169.1|refseq:NP_115987.2|refseq:NP_001164168.1|refseq:NP_001164166.1|refseq:NP_001164170.1 ensemblbacteria:AAO90328(transcript)|ensemblbacteria:CBU_0794(gene)|refseq:NP_819814.1|refseq:WP_010957806.1|mint:Q83DE4 - comment:mint|comment:homomint - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:6SGHXJywVk383ITHBKxLAhAfXuE9606 rogid:XVA7R483yYdpYkhCnAqOzU8u000227377 rigid:yh+SmbInX4RQAn3qysZ00od6BuQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DE4 uniprotkb:P62714 intact:EBI-21285423|ensemblbacteria:AAO90328 intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5 psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name) psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285483|imex:IM-26899-113 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90328(transcript)|ensemblbacteria:CBU_0794(gene)|refseq:NP_819814.1|refseq:WP_010957806.1|mint:Q83DE4 refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:XVA7R483yYdpYkhCnAqOzU8u000227377 rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606 rigid:+QHX2poJGJQPN1OJ9hvwKoqC/jQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DE4 uniprotkb:P62191 intact:EBI-21285423|ensemblbacteria:AAO90328 intact:EBI-357598|uniprotkb:P49014|uniprotkb:Q03527|uniprotkb:Q6IAW0|uniprotkb:Q96AZ3|ensembl:ENSP00000261303|uniprotkb:Q6NW36|uniprotkb:B4DR63 psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name) psi-mi:prs4_human(display_long)|uniprotkb:PSMC1(gene name)|psi-mi:PSMC1(display_short)|uniprotkb:26S proteasome AAA-ATPase subunit RPT2(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285489|imex:IM-26899-227 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90328(transcript)|ensemblbacteria:CBU_0794(gene)|refseq:NP_819814.1|refseq:WP_010957806.1|mint:Q83DE4 refseq:NP_002793.2|ensembl:ENST00000261303(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|ensembl:ENSG00000100764(gene)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035244|interpro:IPR041569|mint:P62191|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFQ|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-8852276|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|refseq:NP_001317141.1|refseq:XP_016876959.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:XVA7R483yYdpYkhCnAqOzU8u000227377 rogid:oGEtU7Cv0qversbD3WQgAo5H9pM9606 rigid:R7OMSz+56r4qIZ3eHLqjGiFtu04 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DE4 uniprotkb:Q9P0K7 intact:EBI-21285423|ensemblbacteria:AAO90328 intact:EBI-1023749|uniprotkb:Q6V1W9|uniprotkb:Q7Z5I4|uniprotkb:Q7Z733|uniprotkb:Q9P2L2|uniprotkb:Q9Y3T5|uniprotkb:E9PED3|intact:EBI-2555698|ensembl:ENSP00000265109|ensembl:ENSP00000388725|ensembl:ENSP00000422942 psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name) psi-mi:rai14_human(display_long)|uniprotkb:Ankyrin repeat and coiled-coil structure-containing protein(gene name synonym)|uniprotkb:Retinoic acid-induced protein 14(gene name synonym)|uniprotkb:Novel retinal pigment epithelial cell protein(gene name synonym)|uniprotkb:RAI14(gene name)|psi-mi:RAI14(display_short)|uniprotkb:KIAA1334(gene name synonym)|uniprotkb:NORPEG(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285495|imex:IM-26899-649 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90328(transcript)|ensemblbacteria:CBU_0794(gene)|refseq:NP_819814.1|refseq:WP_010957806.1|mint:Q83DE4 refseq:NP_001138992.1|refseq:NP_001138993.1|refseq:NP_001138994.1|refseq:NP_001138995.1|refseq:NP_001138997.1|refseq:NP_056392.2|refseq:XP_011512319.1|refseq:XP_011512320.1|refseq:XP_011512321.1|refseq:XP_011512322.1|refseq:XP_011512323.1|refseq:XP_011512324.1|ensembl:ENSG00000039560(gene)|ensembl:ENST00000265109(transcript)|ensembl:ENST00000428746(transcript)|ensembl:ENST00000503673(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005938"(cell cortex)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR042420|mint:Q9P0K7|refseq:XP_006714532.1|refseq:XP_016864824.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:XVA7R483yYdpYkhCnAqOzU8u000227377 rogid:m5hQYx6HEi9QEAey1UiNpeAp6tw9606 rigid:/wShsi0zAgeJgtzadFgVS/fBv9Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q9Y6W3 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-1765641|ensembl:ENSP00000253693 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:can7_human(display_long)|uniprotkb:CAPN7(gene name)|psi-mi:CAPN7(display_short)|uniprotkb:PALBH(gene name synonym)|uniprotkb:PalB homolog(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285598|imex:IM-26899-651 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_055111.1|ensembl:ENSG00000131375(gene)|ensembl:ENST00000253693(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090541"(MIT domain binding)|go:"GO:0097264"(self proteolysis)|interpro:IPR001300(Peptidase C2, calpain)|interpro:IPR007330(MIT)|interpro:IPR022682|interpro:IPR022683|interpro:IPR022684|interpro:IPR036181|interpro:IPR036213|interpro:IPR038765|mint:Q9Y6W3|rcsb pdb:2QFE|reactome:R-HSA-1474228 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:tRDBeVQRu1tuCDWtSrve/Y9lWsg9606 rigid:DyutS351B8hRDyyp+xK8AdyZP3M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q96LL4 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-751596|uniprotkb:Q96LJ9|ensembl:ENSP00000297324 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:ch048_human(display_long)|uniprotkb:C8orf48(gene name)|psi-mi:C8orf48(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285592|imex:IM-26899-347 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_001007091.1|ensembl:ENSG00000164743(gene)|ensembl:ENST00000297324(transcript)|interpro:IPR027932|mint:Q96LL4 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:JPB4E+42Jc1w9k0ExNOu0GOi9AQ9606 rigid:U5sKulx4QWIjFOEb9gySTEL/2A0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q9BZE7 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-10303102|uniprotkb:Q96M68|uniprotkb:Q5JYU9|ensembl:ENSP00000384667|ensembl:ENSP00000384618|ensembl:ENSP00000249079 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:evg1_human(display_long)|uniprotkb:C22orf23(gene name)|psi-mi:C22orf23(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285586|imex:IM-26899-233 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_001193991.1|refseq:NP_115950.3|ensembl:ENST00000249079(transcript)|ensembl:ENST00000403026(transcript)|ensembl:ENST00000403305(transcript)|interpro:IPR007914(Protein of unknown function UPF0193)|mint:Q9BZE7|ensembl:ENSG00000128346(gene) - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:1/If0SoE7GFjWPn/KgsZ/nF0kfA9606 rigid:lisFoAX3E0zza6ytc1pVY/Prp6I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q68CP9 uniprotkb:Q83D60 intact:EBI-637818|uniprotkb:Q15KG9|uniprotkb:Q5EB51|uniprotkb:Q645I3|uniprotkb:Q6ZRY5|uniprotkb:Q7Z3I5|uniprotkb:Q86T28|uniprotkb:Q96SJ6|uniprotkb:Q9HCL5|ensembl:ENSP00000335044 intact:EBI-21285556|ensemblbacteria:AAO90413 psi-mi:arid2_human(display_long)|uniprotkb:BRG1-associated factor 200(gene name synonym)|uniprotkb:Zinc finger protein with activation potential(gene name synonym)|uniprotkb:Zipzap/p200(gene name synonym)|uniprotkb:ARID2(gene name)|psi-mi:ARID2(display_short)|uniprotkb:KIAA1557(gene name synonym)|uniprotkb:BAF200(gene name synonym) psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285580|imex:IM-26899-345 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_689854.2|ensembl:ENSG00000189079(gene)|ensembl:ENST00000334344(transcript)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042592"(homeostatic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048568"(embryonic organ development)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR036388|interpro:IPR036390|interpro:IPR036431|mint:Q68CP9|reactome:R-HSA-3214858|reactome:R-HSA-8939243|dip:DIP-33391N|refseq:NP_001334768.1|ensembl:ENSP00000335044 ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:7AJ6PqICERVZS+s3sZBIBODzs/I9606 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rigid:+TsiYi8O1ve39fliPp/FgOP8wPs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DE4 uniprotkb:Q96K75 intact:EBI-21285423|ensemblbacteria:AAO90328 intact:EBI-6660752|ensembl:ENSP00000295208|ensembl:ENSP00000405509|uniprotkb:Q5JPJ3 psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name) psi-mi:zn514_human(display_long)|uniprotkb:ZNF514(gene name)|psi-mi:ZNF514(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285513|imex:IM-26899-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90328(transcript)|ensemblbacteria:CBU_0794(gene)|refseq:NP_819814.1|refseq:WP_010957806.1|mint:Q83DE4 ensembl:ENSG00000144026(gene)|ensembl:ENST00000295208(transcript)|ensembl:ENST00000411425(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|mint:Q96K75|reactome:R-HSA-212436|refseq:NP_001304934.1|refseq:NP_116177.1|refseq:XP_006712869.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:XVA7R483yYdpYkhCnAqOzU8u000227377 rogid:qw27vebM3X0BDC5K6dmpFCHIf8c9606 rigid:s5pEWxoijKNhHtQMjxUJSrsj1n8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q92527 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-725852|uniprotkb:Q96QN1|uniprotkb:Q9UDM3|uniprotkb:B4DYF5|ensembl:ENSP00000265224 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:ankr7_human(display_long)|uniprotkb:Testis-specific protein TSA806(gene name synonym)|uniprotkb:ANKRD7(gene name)|psi-mi:ANKRD7(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285568|imex:IM-26899-123 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_062618.2|ensembl:ENST00000265224(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q92527|ensembl:ENSG00000106013(gene) - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:uytbHTgjbeon7IxDmO/PD8ZcXtM9606 rigid:QGOWZYWxjXqT6fsKDxTwfWV+uE4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q02252 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-2107242|uniprotkb:Q9UKM8|uniprotkb:B2R609|uniprotkb:B4DFS8|uniprotkb:J3KNU8|ensembl:ENSP00000450436 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:mmsa_human(display_long)|uniprotkb:MMSDH(gene name synonym)|uniprotkb:Aldehyde dehydrogenase family 6 member A1(gene name synonym)|uniprotkb:ALDH6A1(gene name)|psi-mi:ALDH6A1(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285562|imex:IM-26899-231 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_005580.1|refseq:NP_001265522.1|ensembl:ENSG00000119711(gene)|ensembl:ENST00000553458(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004491"("methylmalonate-semialdehyde dehydrogenase (acylating) activity")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006210"(thymine catabolic process)|go:"GO:0006573"(valine metabolic process)|go:"GO:0006574"(valine catabolic process)|go:"GO:0009083"(branched-chain amino acid catabolic process)|go:"GO:0018478"("malonate-semialdehyde dehydrogenase (acetylating) activity")|go:"GO:0019859"(thymine metabolic process)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0102662"("malonate-semialdehyde dehydrogenase (acetylating, NAD+) activity")|interpro:IPR010061(Methylmalonate-semialdehyde dehydrogenase)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|mint:Q02252|reactome:R-HSA-70895 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:9tRJSF7S26Z8N2WYcURXRoOLfFw9606 rigid:oet4n0j6mWd6tiTSsWnzel81X/Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DE4 uniprotkb:Q14966 intact:EBI-21285423|ensemblbacteria:AAO90328 intact:EBI-742207|uniprotkb:B5MDV1|uniprotkb:Q53R34|uniprotkb:Q5XJ05|uniprotkb:Q68DP3|uniprotkb:Q6P2H2|uniprotkb:Q7Z3T7|uniprotkb:Q8NF92|uniprotkb:Q8TCA1|uniprotkb:Q9H2G1|uniprotkb:Q9NP37|uniprotkb:B7ZLD1|ensembl:ENSP00000264447|ensembl:ENSP00000386433|uniprotkb:A0A096LPH6 psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name) psi-mi:zn638_human(display_long)|uniprotkb:ZNF638(gene name)|psi-mi:ZNF638(display_short)|uniprotkb:NP220(gene name synonym)|uniprotkb:ZFML(gene name synonym)|uniprotkb:Zinc finger matrin-like protein(gene name synonym)|uniprotkb:Nuclear protein 220(gene name synonym)|uniprotkb:Cutaneous T-cell lymphoma-associated antigen se33-1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285550|imex:IM-26899-121 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90328(transcript)|ensemblbacteria:CBU_0794(gene)|refseq:NP_819814.1|refseq:WP_010957806.1|mint:Q83DE4 refseq:NP_001014972.1|refseq:NP_055312.2|refseq:NP_001239541.1|refseq:NP_001239542.1|ensembl:ENSG00000075292(gene)|ensembl:ENST00000264447(transcript)|ensembl:ENST00000409544(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022755|interpro:IPR033096|interpro:IPR035979|interpro:IPR036236|mint:Q14966|rcsb pdb:6SXW|reactome:R-HSA-381340|go:"GO:0003690"(double-stranded DNA binding)|ensembl:ENSP00000264447|ensembl:ENSP00000386433|ensembl:ENST00000410075|ensembl:ENSP00000485608|dip:DIP-42386N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:XVA7R483yYdpYkhCnAqOzU8u000227377 rogid:KkoO3Hgmx9CwI4LgVmk2ankakIY9606 rigid:FjIfhat8ElR1ifZnOyjlVgrdRoo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DE4 uniprotkb:Q96ND8 intact:EBI-21285423|ensemblbacteria:AAO90328 intact:EBI-21285519|ensembl:ENSP00000291598|ensembl:ENSP00000388502|uniprotkb:O14850|uniprotkb:Q2NKK3 psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name) psi-mi:zn583_human(display_long)|uniprotkb:ZNF583(gene name)|psi-mi:ZNF583(display_short)|uniprotkb:Zinc finger protein L3-5(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285544|imex:IM-26899-343 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90328(transcript)|ensemblbacteria:CBU_0794(gene)|refseq:NP_819814.1|refseq:WP_010957806.1|mint:Q83DE4 ensembl:ENSG00000198440(gene)|ensembl:ENST00000291598(transcript)|ensembl:ENST00000333201(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|mint:Q96ND8|reactome:R-HSA-212436|refseq:NP_001153332.1|refseq:NP_001153333.1|refseq:NP_689691.2|refseq:XP_011524819.1|refseq:XP_016881839.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:XVA7R483yYdpYkhCnAqOzU8u000227377 rogid:K5sTOQhO2w/s5N/S+t9aFNGP/Ns9606 rigid:+yL4MNs50rgEnydBlD4VfoBYthw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q8WW43 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-2606497|uniprotkb:Q6UWQ1|uniprotkb:Q9H0S0|uniprotkb:A8K589|ensembl:ENSP00000261879|uniprotkb:Q564N3 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:aph1b_human(display_long)|uniprotkb:APH1B(gene name)|psi-mi:APH1B(display_short)|uniprotkb:PSFL(gene name synonym)|uniprotkb:Aph-1beta(gene name synonym)|uniprotkb:Presenilin-stabilization factor-like(gene name synonym)|uniprotkb:UNQ688/PRO1328(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285574|imex:IM-26899-751 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_112591.2|ensembl:ENSG00000138613(gene)|ensembl:ENST00000261879(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007220"(Notch receptor processing)|go:"GO:0007626"(locomotory behavior)|go:"GO:0010008"(endosome membrane)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016485"(protein processing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034205"(amyloid-beta formation)|go:"GO:0042987"(amyloid precursor protein catabolic process)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0070765"(gamma-secretase complex)|interpro:IPR009294(Aph-1)|mint:Q8WW43|reactome:R-HSA-1251985|reactome:R-HSA-193692|reactome:R-HSA-205043|reactome:R-HSA-2122948|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3928665|reactome:R-HSA-9013507|reactome:R-HSA-9013700|reactome:R-HSA-9017802|reactome:R-HSA-977225|refseq:NP_001139118.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:w8GOGnbWB3OPYAAfOxy/YCzlXPo9606 rigid:m+jeODlH/zaxu4Xg0simF6VUsv0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q8TCE6 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-725416|uniprotkb:Q9NXW4|uniprotkb:B1AMV6|uniprotkb:B4DDC3|uniprotkb:D3DRC8|ensembl:ENSP00000354688 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:den10_human(display_long)|uniprotkb:DENND10(gene name)|psi-mi:DENND10(display_short)|uniprotkb:FAM45A(gene name synonym)|uniprotkb:Protein FAM45A(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285658|imex:IM-26899-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_996892.1|refseq:NP_001290040.1|refseq:NP_001290041.1|refseq:NP_001290042.1|ensembl:ENSG00000119979(gene)|ensembl:ENST00000361432(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005770"(late endosome)|go:"GO:0015031"(protein transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|interpro:IPR037516|interpro:IPR042431|mint:Q8TCE6|refseq:XP_016871750.1|refseq:XP_016871751.1|refseq:XP_016871752.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:y2TwrFW/ss6WtsUMVIVRCG8lEKk9606 rigid:CRC0QfaenXbT9ZEB5DYZRM8zBzo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P12259 uniprotkb:Q83D60 intact:EBI-9640912|uniprotkb:A8K6E8|uniprotkb:Q14285|uniprotkb:Q5R346|uniprotkb:Q8WWQ6|uniprotkb:Q6UPU6|uniprotkb:Q2EHR5|uniprotkb:Q5R347|ensembl:ENSP00000356771 intact:EBI-21285556|ensemblbacteria:AAO90413 psi-mi:fa5_human(display_long)|uniprotkb:F5(gene name)|psi-mi:F5(display_short)|uniprotkb:Activated protein C cofactor(gene name synonym)|uniprotkb:Proaccelerin, labile factor(gene name synonym) psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285652|imex:IM-26899-239 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000121.2|dip:DIP-47331N|ensembl:ENSG00000198734(gene)|ensembl:ENST00000367797(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0007596"(blood coagulation)|go:"GO:0008015"(blood circulation)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR008972(Cupredoxin)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009271(Coagulation factor V LSPD)|interpro:IPR011707(Multicopper oxidase, type 3)|interpro:IPR024715|interpro:IPR033138|mint:P12259|rcsb pdb:1CZS|rcsb pdb:1CZT|rcsb pdb:1CZV|rcsb pdb:1FV4|rcsb pdb:1Y61|rcsb pdb:3P6Z|rcsb pdb:3P70|rcsb pdb:3S9C|rcsb pdb:7KVE|rcsb pdb:7KVF|rcsb pdb:7KXY|reactome:R-HSA-114608|reactome:R-HSA-140875|reactome:R-HSA-204005|reactome:R-HSA-381426|reactome:R-HSA-5694530|reactome:R-HSA-8957275 ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:i1+4mzlwzNvSHZ2CketeTEvnJEQ9606 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rigid:nTivqtnHuL9ph/1RxTza4T4lQ28 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q8TC29 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-9246952|uniprotkb:A8K8Y0|uniprotkb:D3DRV2|ensembl:ENSP00000331044|ensembl:ENSP00000432930 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:enkur_human(display_long)|uniprotkb:ENKUR(gene name)|psi-mi:ENKUR(display_short)|uniprotkb:C10orf63(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285646|imex:IM-26899-237 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_001257312.1|refseq:NP_659447.1|refseq:XP_011517650.1|ensembl:ENSG00000151023(gene)|ensembl:ENST00000331161(transcript)|ensembl:ENST00000496261(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005516"(calmodulin binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0061966"(establishment of left/right asymmetry)|go:"GO:0097228"(sperm principal piece)|go:"GO:0097728"(9+0 motile cilium)|go:"GO:0097729"(9+2 motile cilium)|interpro:IPR026150|interpro:IPR027012|mint:Q8TC29 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:N9U7aJBZ/aBSi1boD3iQZfyWAbA9606 rigid:QOOjQ7Xvhd2VhH63Ir61jAVmtnM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q5JVL4 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-743105|ensembl:ENSP00000360107|uniprotkb:Q5XKM4|uniprotkb:Q6E1U7|uniprotkb:Q6E1U8|uniprotkb:Q8WUL2|uniprotkb:Q9NVW6|intact:EBI-11099619|uniprotkb:B4DMU3|uniprotkb:F5GZD8 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:efhc1_human(display_long)|uniprotkb:EFHC1(gene name)|psi-mi:EFHC1(display_short)|uniprotkb:Myoclonin-1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285640|imex:IM-26899-235 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 ensembl:ENST00000371068(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000922"(spindle pole)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005813"(centrosome)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0021795"(cerebral cortex cell migration)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051302"(regulation of cell division)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0072686"(mitotic spindle)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006602(Region of unknown function DM10)|interpro:IPR011992(EF-Hand type)|interpro:IPR040193|mint:Q5JVL4|refseq:NP_001165891.1|refseq:NP_060570.2|ensembl:ENSG00000096093(gene) - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:l5I5K4Lgihe08j5BuPBk4uDY+qk9606 rigid:0I1OEHD17+5v0ClLdq5V/RPS5Q4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5TID7 uniprotkb:Q83D60 intact:EBI-7267656|uniprotkb:Q8TC48|uniprotkb:O60780|intact:MINT-1193587|uniprotkb:Q53FD5|uniprotkb:Q5TID9|ensembl:ENSP00000356780 intact:EBI-21285556|ensemblbacteria:AAO90413 psi-mi:cc181_human(display_long)|uniprotkb:CCDC181(gene name)|psi-mi:CCDC181(display_short)|uniprotkb:C1orf114(gene name synonym) psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285604|imex:IM-26899-455 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001287897.1|refseq:NP_001287898.1|refseq:XP_011508129.1|refseq:NP_067002.1|refseq:XP_016857429.1|refseq:XP_005245440.1|ensembl:ENSG00000117477(gene)|ensembl:ENST00000367806(transcript)|go:"GO:0002177"(manchette)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0036126"(sperm flagellum)|interpro:IPR026687|mint:Q5TID7|refseq:XP_016857427.1|refseq:XP_016857428.1 ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 - comment:mint|comment:homomint - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:z5m86YqgyvVxXNxAwByvwx8iYNI9606 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rigid:0z0GCGwCJBSSUI4rMNP+XL9aFsU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q58WW2 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-2559044|ensembl:ENSP00000311949|uniprotkb:Q8TB19|uniprotkb:Q8IXH3|uniprotkb:A2A295|uniprotkb:Q7L8I0|uniprotkb:B4DNB8 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:dcaf6_human(display_long)|uniprotkb:DCAF6(gene name)|psi-mi:DCAF6(display_short)|uniprotkb:IQWD1(gene name synonym)|uniprotkb:Nuclear receptor interaction protein(gene name synonym)|uniprotkb:IQ motif and WD repeat-containing protein 1(gene name synonym)|uniprotkb:Androgen receptor complex-associated protein(gene name synonym)|uniprotkb:MSTP055(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285628|imex:IM-26899-655 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 ensembl:ENSG00000143164(gene)|ensembl:ENST00000312263(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030374"(nuclear receptor coactivator activity)|refseq:NP_001017977.1|refseq:NP_001185885.1|refseq:NP_001185886.1|refseq:NP_060912.2|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q58WW2|rcsb pdb:3I7O|reactome:R-HSA-8951664|dip:DIP-44678N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:1CtoPWPj6fdryvDlC46pXiUguDc9606 rigid:SL2YGhKlOaBwieGivUD22hIBeA4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q9BT78 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-742413|uniprotkb:Q561W7|uniprotkb:Q9NW31|uniprotkb:Q9Y677|uniprotkb:B3KN88|ensembl:ENSP00000264389|uniprotkb:B3KST5 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:csn4_human(display_long)|uniprotkb:COPS4(gene name)|psi-mi:COPS4(display_short)|uniprotkb:CSN4(gene name synonym)|uniprotkb:JAB1-containing signalosome subunit 4(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285622|imex:IM-26899-457 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 ensembl:ENSG00000138663(gene)|refseq:NP_057213.2|refseq:NP_001244935.1|go:"GO:0016607"(nuclear speck)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0030054"(cell junction)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037754|interpro:IPR040134|interpro:IPR041406|mint:Q9BT78|rcsb pdb:4D0P|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4WSN|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|reactome:R-HSA-9013422|ensembl:ENST00000264389(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008180"(COP9 signalosome)|refseq:NP_001317656.1|dip:DIP-34516N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:onrZiPzG+bZvycmpDTZMtkPzCfQ9606 rigid:wOEf7H3omLaZgFxS7esWxwzJ+XY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:O00299 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-347404|uniprotkb:Q15089|uniprotkb:Q502X1|ensembl:ENSP00000404037|ensembl:ENSP00000404589|ensembl:ENSP00000406088|ensembl:ENSP00000406335|ensembl:ENSP00000406968|ensembl:ENSP00000407429|ensembl:ENSP00000407791|ensembl:ENSP00000408094|ensembl:ENSP00000408357|ensembl:ENSP00000409247|ensembl:ENSP00000409979|ensembl:ENSP00000410965|ensembl:ENSP00000412217|ensembl:ENSP00000413330|ensembl:ENSP00000416211|ensembl:ENSP00000477623|ensembl:ENSP00000478930|ensembl:ENSP00000479501|ensembl:ENSP00000479808|ensembl:ENSP00000480256|ensembl:ENSP00000482255|ensembl:ENSP00000484581|ensembl:ENSP00000364934|ensembl:ENSP00000364935|ensembl:ENSP00000364940|ensembl:ENSP00000372896|ensembl:ENSP00000372897|ensembl:ENSP00000379229|ensembl:ENSP00000382926|ensembl:ENSP00000382931|ensembl:ENSP00000391395|ensembl:ENSP00000398056|ensembl:ENSP00000400280|ensembl:ENSP00000400532|ensembl:ENSP00000401292 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:clic1_human(display_long)|uniprotkb:CLIC1(gene name)|psi-mi:CLIC1(display_short)|uniprotkb:NCC27(gene name synonym)|uniprotkb:Nuclear chloride ion channel 27(gene name synonym)|uniprotkb:Chloride channel ABP(gene name synonym)|uniprotkb:Regulatory nuclear chloride ion channel protein(gene name synonym)|uniprotkb:G6(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285616|imex:IM-26899-125 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_001279.2|refseq:NP_001274522.1|refseq:NP_001274523.1|ensembl:ENST00000375779(transcript)|ensembl:ENST00000375780(transcript)|ensembl:ENST00000375784(transcript)|ensembl:ENST00000383404(transcript)|ensembl:ENST00000383405(transcript)|ensembl:ENST00000395892(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006821"(chloride transport)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0034707"(chloride channel complex)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0045296"(cadherin binding)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0072562"(blood microparticle)|interpro:IPR002946(Intracellular chloride channel)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR030259|go:"GO:0005634"(nucleus)|ensembl:ENSG00000206394(gene)|ensembl:ENSG00000213719(gene)|ensembl:ENSG00000223639(gene)|ensembl:ENSG00000226248(gene)|ensembl:ENSG00000226417(gene)|ensembl:ENSG00000226651(gene)|ensembl:ENSG00000230685(gene)|ensembl:ENST00000400052(transcript)|ensembl:ENST00000400058(transcript)|ensembl:ENST00000415179(transcript)|ensembl:ENST00000418285(transcript)|ensembl:ENST00000420458(transcript)|ensembl:ENST00000422167(transcript)|ensembl:ENST00000423055(transcript)|ensembl:ENST00000423143(transcript)|ensembl:ENST00000423804(transcript)|ensembl:ENST00000425464(transcript)|ensembl:ENST00000431921(transcript)|ensembl:ENST00000433916(transcript)|ensembl:ENST00000434202(transcript)|ensembl:ENST00000435242(transcript)|ensembl:ENST00000438708(transcript)|ensembl:ENST00000438750(transcript)|ensembl:ENST00000442045(transcript)|ensembl:ENST00000447338(transcript)|ensembl:ENST00000447369(transcript)|ensembl:ENST00000451546(transcript)|ensembl:ENST00000456863(transcript)|ensembl:ENST00000457485(transcript)|ensembl:ENST00000614673(transcript)|ensembl:ENST00000614982(transcript)|ensembl:ENST00000616760(transcript)|ensembl:ENST00000618288(transcript)|ensembl:ENST00000619727(transcript)|ensembl:ENST00000621055(transcript)|ensembl:ENST00000622613(transcript)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005615"(extracellular space)|interpro:IPR036282|interpro:IPR040079|mint:O00299|interpro:IPR036249|rcsb pdb:1K0M|rcsb pdb:1K0N|rcsb pdb:1K0O|rcsb pdb:1RK4|rcsb pdb:3O3T|rcsb pdb:3P8W|rcsb pdb:3P90|rcsb pdb:3QR6|rcsb pdb:3SWL|rcsb pdb:3TGZ|rcsb pdb:3UVH|rcsb pdb:4IQA|rcsb pdb:4JZQ|rcsb pdb:4K0G|rcsb pdb:4K0N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:HVux62IcNdqcPgqmlGlIyZTLpFo9606 rigid:T24+LUhe6DOeg5Y+CuowJSooCCk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:P78371 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285610|imex:IM-26899-653 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606 rigid:Tlk7Df2M/I+gg1vW7QVn0YHXn8k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:O00399 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-2559415|uniprotkb:B2RAC1|ensembl:ENSP00000221114 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:dctn6_human(display_long)|uniprotkb:DCTN6(gene name)|psi-mi:DCTN6(display_short)|uniprotkb:WS3(gene name synonym)|uniprotkb:Dynactin subunit p27(gene name synonym)|uniprotkb:Protein WS-3(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285634|imex:IM-26899-565 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_006562.1|ensembl:ENSG00000104671(gene)|ensembl:ENST00000221114(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0070840"(dynein complex binding)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR027777|mint:O00399|rcsb pdb:3TV0|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:+35O26TEIL5l1I7XrNJcl6BA77c9606 rigid:EfaYGRCh3l3nsqovsatet4tcr0M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q86X45 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-9379658|uniprotkb:Q13648|uniprotkb:Q4G183|ensembl:ENSP00000429791|ensembl:ENSP00000484634 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:daa11_human(display_long)|uniprotkb:DNAAF11(gene name)|psi-mi:DNAAF11(display_short)|uniprotkb:LRRC6(gene name synonym)|uniprotkb:LRTP(gene name synonym)|uniprotkb:Leucine-rich repeat-containing protein 6(gene name synonym)|uniprotkb:Leucine-rich testis-specific protein(gene name synonym)|uniprotkb:Protein tilB homolog(gene name synonym)|uniprotkb:TSLRP(gene name synonym)|uniprotkb:Testis-specific leucine-rich repeat protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285724|imex:IM-26899-463 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_001308890.1|refseq:NP_001308891.1|refseq:NP_001308892.1|refseq:NP_001308893.1|refseq:NP_001308894.1|refseq:NP_001308895.1|refseq:NP_036604.2|go:"GO:0120293"(dynein axonemal particle)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR007052(CS domain)|interpro:IPR032675|mint:Q86X45|ensembl:ENSG00000129295(gene)|ensembl:ENST00000519595(transcript)|ensembl:ENST00000620350(transcript)|go:"GO:0003341"(cilium movement)|go:"GO:0003351"(epithelial cilium movement involved in extracellular fluid movement)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0008584"(male gonad development)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0031514"(motile cilium)|go:"GO:0036158"(outer dynein arm assembly)|go:"GO:0036159"(inner dynein arm assembly)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0051649"(establishment of localization in cell)|go:"GO:0060287"(epithelial cilium movement involved in determination of left/right asymmetry)|go:"GO:0061458"(reproductive system development)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0070286"(axonemal dynein complex assembly)|go:"GO:0090651"(apical cytoplasm)|go:"GO:0090660"(cerebrospinal fluid circulation)|go:"GO:0120229"(protein localization to motile cilium) - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:+KWpDTd1pD7UAK4rVDo5We0inVw9606 rigid:pps4RPiD79F2yvOXBPrx+9q8cDs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:P53990 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-945994|intact:EBI-4324656|uniprotkb:A8KAH5|uniprotkb:Q9BQ81|uniprotkb:Q9BWN2|uniprotkb:Q3SYM4|uniprotkb:J3QLU7 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:ist1_human(display_long)|uniprotkb:IST1(gene name)|psi-mi:IST1(display_short)|uniprotkb:Putative MAPK-activating protein PM28(gene name synonym)|uniprotkb:KIAA0174(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285718|imex:IM-26899-349 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_055576.2|refseq:NP_001257904.1|refseq:NP_001257906.1|refseq:NP_001257905.1|refseq:NP_001257907.1|mint:P53990|dip:DIP-42546N|go:"GO:0005576"(extracellular region)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008104"(protein localization)|go:"GO:0009838"(abscission)|go:"GO:0015031"(protein transport)|go:"GO:0019076"(viral release from host cell)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030496"(midbody)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046745"(viral capsid secondary envelopment)|go:"GO:0048672"(positive regulation of collateral sprouting)|go:"GO:0051301"(cell division)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090541"(MIT domain binding)|go:"GO:0090543"(Flemming body)|go:"GO:1904903"(ESCRT III complex disassembly)|interpro:IPR005061(Protein of unknown function DUF292, eukaryotic)|interpro:IPR042277|rcsb pdb:3FRR|rcsb pdb:3FRS|rcsb pdb:3JC1|rcsb pdb:4U7E|rcsb pdb:4U7I|rcsb pdb:4U7Y|rcsb pdb:4WZX|rcsb pdb:6E8G|rcsb pdb:6TZ4|rcsb pdb:6TZ5|rcsb pdb:6TZA|reactome:R-HSA-6798695|reactome:R-HSA-9668328 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:RbWwKZ+sftO2x3UkFz8zAxVi2CU9606 rigid:eqQASWaMPPyDWSmest4l7rFj5t4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q13123 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-713456|uniprotkb:Q6IPD8|ensembl:ENSP00000396301 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:red_human(display_long)|uniprotkb:Protein RER(gene name synonym)|uniprotkb:IK factor(gene name synonym)|uniprotkb:Cytokine IK(gene name synonym)|uniprotkb:IK(gene name)|psi-mi:IK(display_short)|uniprotkb:RED(gene name synonym)|uniprotkb:RER(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285712|imex:IM-26899-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 ensembl:ENSG00000113141(gene)|ensembl:ENST00000417647(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0016607"(nuclear speck)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0042802"(identical protein binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|interpro:IPR012492(RED-like, C-terminal)|interpro:IPR012916(RED-like, N-terminal)|interpro:IPR039896|mint:Q13123|rcsb pdb:5O9Z|rcsb pdb:6Q8I|refseq:NP_006074.2 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:EBUQl+Gj0ozHP85Uh4xc9q2Vr6Y9606 rigid:5M0PxBJlIH/Dlby/jw9f6QOmTi0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8WYA0 uniprotkb:Q83D60 intact:EBI-11321879|uniprotkb:Q8NB51|uniprotkb:Q9UNY8|uniprotkb:Q2YDY1|uniprotkb:Q9BSV2|ensembl:ENSP00000242591|ensembl:ENSP00000449718 intact:EBI-21285556|ensemblbacteria:AAO90413 psi-mi:ift81_human(display_long)|uniprotkb:IFT81(gene name)|psi-mi:IFT81(display_short)|uniprotkb:CDV1(gene name synonym)|uniprotkb:Carnitine deficiency-associated protein expressed in ventricle 1(gene name synonym) psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285706|imex:IM-26899-661 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016874706.1|refseq:NP_001137251.1|refseq:NP_054774.2|refseq:NP_113661.2|refseq:NP_001334875.1|ensembl:ENSG00000122970(gene)|ensembl:ENST00000242591(transcript)|ensembl:ENST00000552912(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0015631"(tubulin binding)|go:"GO:0030992"(intraciliary transport particle B)|go:"GO:0031514"(motile cilium)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042073"(intraciliary transport)|go:"GO:0060271"(cilium assembly)|go:"GO:0097542"(ciliary tip)|interpro:IPR029600|interpro:IPR041146|interpro:IPR043016|mint:Q8WYA0|reactome:R-HSA-5620924 ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:2+081wYMeK1gK+kuJRx3DFuiaGU9606 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rigid:1BeFVSzvfWgRt/h6q4f+BXs0Cy4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q9NSE4 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-1054770|uniprotkb:B2RPG8|uniprotkb:Q1M2P9|uniprotkb:Q6PI85|uniprotkb:Q7L439|uniprotkb:Q86WU9|uniprotkb:Q96D91|uniprotkb:Q9H9Q8|uniprotkb:Q9NW42|ensembl:ENSP00000355889 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:syim_human(display_long)|uniprotkb:IARS2(gene name)|psi-mi:IARS2(display_short)|uniprotkb:Isoleucyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285700|imex:IM-26899-659 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_060530.3|ensembl:ENSG00000067704(gene)|ensembl:ENST00000366922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004822"(isoleucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006428"(isoleucyl-tRNA aminoacylation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002301(Isoleucyl-tRNA synthetase, class Ia)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR010663(DNA glycosylase/AP lyase and isoleucyl tRNA synthetase, zinc finger domain)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR023585|interpro:IPR033708|mint:Q9NSE4|reactome:R-HSA-379726 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:+3/hUjD0USVo2/G+Z9aOKpQKwhE9606 rigid:JaivoSuemMz+vo3ANQhZZ/e27nM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q9NP50 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-741906|ensembl:ENSP00000337477|ensembl:ENSP00000393279|ensembl:ENSP00000479093|ensembl:ENSP00000488570|uniprotkb:Q9BSZ8|uniprotkb:D3DUV8 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:shcaf_human(display_long)|uniprotkb:SINHCAF(gene name)|psi-mi:SINHCAF(display_short)|uniprotkb:C12orf14(gene name synonym)|uniprotkb:FAM60A(gene name synonym)|uniprotkb:Protein FAM60A(gene name synonym)|uniprotkb:Tera protein homolog(gene name synonym)|uniprotkb:L4(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285664|imex:IM-26899-461 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 ensembl:ENSG00000139146(gene)|ensembl:ENSG00000276371(gene)|ensembl:ENST00000337682(transcript)|ensembl:ENST00000454658(transcript)|ensembl:ENST00000617411(transcript)|ensembl:ENST00000633702(transcript)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0045596"(negative regulation of cell differentiation)|interpro:IPR026065|mint:Q9NP50|refseq:NP_001129283.1|refseq:NP_001129284.1|refseq:NP_067061.1|refseq:XP_016875247.1|refseq:XP_016875248.1|refseq:XP_016875249.1|refseq:XP_016875250.1|refseq:XP_016875251.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:LVESO8KQhobNYQduBQ/iAmNaNTM9606 rigid:UJqXZov6x8YBXcn0B7qOGuDBNCk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:P50395 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-1049143|uniprotkb:O43928|uniprotkb:Q9UQM6|ensembl:ENSP00000369538|uniprotkb:Q5SX88 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:gdib_human(display_long)|uniprotkb:Guanosine diphosphate dissociation inhibitor 2(gene name synonym)|uniprotkb:GDI2(gene name)|psi-mi:GDI2(display_short)|uniprotkb:RABGDIB(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285688|imex:IM-26899-753 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 ensembl:ENSG00000057608(gene)|ensembl:ENST00000380191(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031982"(vesicle)|go:"GO:0034774"(secretory granule lumen)|refseq:NP_001108628.1|refseq:NP_001485.2|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|mint:P50395|reactome:R-HSA-6798695|reactome:R-HSA-8876198|dip:DIP-50593N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:KTUS915xP+QA9QFU2aZSyS+Hkgc9606 rigid:aYKuzChPjJuXwRm6QLGFVVUuPsU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q9NXN4 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-10316460|uniprotkb:Q96DZ0|ensembl:ENSP00000358451 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:gdap2_human(display_long)|uniprotkb:GDAP2(gene name)|psi-mi:GDAP2(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285682|imex:IM-26899-131 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_001129061.1|refseq:NP_060156.1|ensembl:ENSG00000196505(gene)|ensembl:ENST00000369443(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0032526"(response to retinoic acid)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR002589(Appr-1-p processing)|interpro:IPR035793|interpro:IPR036865|interpro:IPR043472|mint:Q9NXN4|rcsb pdb:4UML - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:2fjIQzKGImu2CwNw2ul5gti/28g9606 rigid:a89t1FSvlGWGh/UMdVF4fI3ASiI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:P04066 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-2512153|ensembl:ENSP00000363603|uniprotkb:Q14335|uniprotkb:Q8NAC2|uniprotkb:Q3LID0|uniprotkb:Q14334|uniprotkb:B2RBG3 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:fuco_human(display_long)|uniprotkb:FUCA1(gene name)|psi-mi:FUCA1(display_short)|uniprotkb:Alpha-L-fucoside fucohydrolase 1(gene name synonym)|uniprotkb:Alpha-L-fucosidase I(gene name synonym)|uniprotkb:Nbla10230(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285676|imex:IM-26899-129 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 ensembl:ENSG00000179163(gene)|ensembl:ENST00000374479(transcript)|go:"GO:0004560"(alpha-L-fucosidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0006004"(fucose metabolic process)|go:"GO:0006027"(glycosaminoglycan catabolic process)|go:"GO:0016139"(glycoside catabolic process)|go:"GO:0019377"(glycolipid catabolic process)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000933("Glycoside hydrolase, family 29 (alpha-L-fucosidase)")|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR016286(Alpha-L-fucosidase)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR018526|interpro:IPR028755|interpro:IPR031919|mint:P04066|reactome:R-HSA-6798695|reactome:R-HSA-975578|refseq:NP_000138.2 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:hzGxBObvRAGMJxL+I9shJUo+nLg9606 rigid:T4JsdWxe1iahMlCZK/Pspfri+/0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q5TBA9 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-2816917|uniprotkb:Q9Y3N6|intact:EBI-28984104|ensembl:ENSP00000445043 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:fry_human(display_long)|uniprotkb:FRY(gene name)|psi-mi:FRY(display_short)|uniprotkb:C13orf14(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285670|imex:IM-26899-127 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_075463.2|ensembl:ENSP00000445043|ensembl:ENSG00000073910(gene)|ensembl:ENST00000542859(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000922"(spindle pole)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005938"(cell cortex)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031175"(neuron projection development)|go:"GO:1904428"(negative regulation of tubulin deacetylation)|interpro:IPR025481|interpro:IPR025614|interpro:IPR029473|interpro:IPR039867|mint:Q5TBA9 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:XSGKUpD+VVyYJ1ew69qbPQnoJWg9606 rigid:imlLBFnUrLm+NVt/aXIYSTIviug false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q96M11 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-720016|uniprotkb:Q96BX9|uniprotkb:B3KXI8|ensembl:ENSP00000348815|ensembl:ENSP00000414884|ensembl:ENSP00000436833 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:hyls1_human(display_long)|uniprotkb:HYLS1(gene name)|psi-mi:HYLS1(display_short)|uniprotkb:HLS(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285694|imex:IM-26899-657 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_001128265.1|refseq:NP_659451.1|ensembl:ENSG00000198331(gene)|ensembl:ENST00000356438(transcript)|ensembl:ENST00000425380(transcript)|ensembl:ENST00000526028(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0060271"(cilium assembly)|go:"GO:0097730"(non-motile cilium)|interpro:IPR026227|interpro:IPR027918|mint:Q96M11|refseq:XP_011540961.1|refseq:XP_005271487.1|refseq:XP_006718840.1|refseq:XP_016872809.1|refseq:XP_016872810.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:6qsYE/EnF7/lGKFARgoQtUurYrk9606 rigid:8hbp7OMtsXAB+0CvPqaEqgqDVj8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:P51955 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-633182|uniprotkb:Q53FD6|uniprotkb:Q5VXZ1|intact:EBI-4311380|uniprotkb:Q5I1Z9|uniprotkb:Q6NZX8|uniprotkb:Q7Z634|uniprotkb:Q86XH2|uniprotkb:Q96QN9|ensembl:ENSP00000355966 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:nek2_human(display_long)|uniprotkb:NEK2A(gene name synonym)|uniprotkb:NimA-like protein kinase 1(gene name synonym)|uniprotkb:HSPK 21(gene name synonym)|uniprotkb:NEK2(gene name)|psi-mi:NEK2(display_short)|uniprotkb:NLK1(gene name synonym)|uniprotkb:Never in mitosis A-related kinase 2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285761|imex:IM-26899-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_001191111.1|refseq:NP_001191112.1|refseq:NP_002488.1|ensembl:ENSG00000117650(gene)|ensembl:ENST00000366999(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0001824"(blastocyst development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030496"(midbody)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0046602"(regulation of mitotic centrosome separation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051299"(centrosome separation)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903126"(negative regulation of centriole-centriole cohesion)|go:"GO:1904355"(positive regulation of telomere capping)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|mint:P51955|rcsb pdb:2JAV|rcsb pdb:2W5A|rcsb pdb:2W5B|rcsb pdb:2W5H|rcsb pdb:2WQO|rcsb pdb:2XK3|rcsb pdb:2XK4|rcsb pdb:2XK6|rcsb pdb:2XK7|rcsb pdb:2XK8|rcsb pdb:2XKC|rcsb pdb:2XKD|rcsb pdb:2XKE|rcsb pdb:2XKF|rcsb pdb:2XNM|rcsb pdb:2XNN|rcsb pdb:2XNO|rcsb pdb:2XNP|rcsb pdb:4A4X|rcsb pdb:4AFE|rcsb pdb:5M51|rcsb pdb:5M53|rcsb pdb:5M55|rcsb pdb:5M57|rcsb pdb:6SGD|rcsb pdb:6SGH|rcsb pdb:6SGI|rcsb pdb:6SGK|rcsb pdb:6SK9|rcsb pdb:6TM5|reactome:R-HSA-179409|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:XP_005273204.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:7iozc82+IF+sGyerzvp571Uc1RM9606 rigid:4Kk5vKrDWEcJ2aNoyeSS8nh5N6s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q96GC5 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-5325315|ensembl:ENSP00000308717|uniprotkb:Q49AK7|uniprotkb:Q4U2Q4|uniprotkb:Q9P091|uniprotkb:Q9Y5J0|intact:EBI-10967301|uniprotkb:B4DN34 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:rm48_human(display_long)|uniprotkb:Mitochondrial large ribosomal subunit protein mL48(gene name synonym)|uniprotkb:CGI-118(orf name)|uniprotkb:HSPC290(orf name)|uniprotkb:MRPL48(gene name)|psi-mi:MRPL48(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285730|imex:IM-26899-663 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 ensembl:ENSG00000175581(gene)|ensembl:ENST00000310614(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|interpro:IPR027486|interpro:IPR027487|mint:Q96GC5|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|interpro:IPR036838|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:6ZSG|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:7OF6|refseq:NP_001305427.1|refseq:NP_001305428.1|refseq:NP_001305429.1|refseq:NP_057139.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:xCdGuctoVF3DrDHZedpDi+IOxxQ9606 rigid:l4QxqotMAJinkEuou2uDWsoloeU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q6P1N2 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-21285736 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:q6p1n2_human(display_long)|uniprotkb:MTIF2(gene name)|psi-mi:MTIF2(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285749|imex:IM-26899-241 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|refseq:NP_001005369.1|refseq:NP_002444.2|interpro:IPR027417|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR015760(Translation initiation factor 2 related)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|mint:Q6P1N2|interpro:IPR044145 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:1tWvOfEeLJfg31GeKiTLztjnehU9606 rigid:rAy/j8Q5yofJ+dX+Dhg/xzq5dGg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:P01106 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-447544|intact:EBI-1058440|uniprotkb:P01107|uniprotkb:Q14026|uniprotkb:A8WFE7|ensembl:ENSP00000367207|ensembl:ENSP00000499105 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:myc_human(display_long)|uniprotkb:BHLHE39(gene name synonym)|uniprotkb:Transcription factor p64(gene name synonym)|uniprotkb:MYC(gene name)|psi-mi:MYC(display_short)|uniprotkb:Proto-oncogene c-Myc(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 39(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285755|imex:IM-26899-755 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_002458.2|dip:DIP-28143N|ensembl:ENSG00000136997(gene)|ensembl:ENST00000377970(transcript)|ensembl:ENST00000652288(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035690"|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044346"(fibroblast apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045656"(negative regulation of monocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051276"(chromosome organization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070848"(response to growth factor)|go:"GO:0070888"(E-box binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090096"(positive regulation of metanephric cap mesenchymal cell proliferation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1904672"(regulation of somatic stem cell population maintenance)|go:"GO:1905643"(positive regulation of DNA methylation)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR002418(Transcription regulator Myc)|interpro:IPR003327(Leucine zipper, Myc)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR012682(Transcription regulator Myc, N-terminal)|interpro:IPR036638|mint:P01106|rcsb pdb:1A93|rcsb pdb:1EE4|rcsb pdb:1MV0|rcsb pdb:1NKP|rcsb pdb:2A93|rcsb pdb:2OR9|rcsb pdb:4Y7R|rcsb pdb:5I4Z|rcsb pdb:5I50|rcsb pdb:6C4U|rcsb pdb:6E16|rcsb pdb:6E24|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015671"(oxygen transport)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0032986"(protein-DNA complex disassembly)|go:"GO:0032991"(protein-containing complex)|reactome:R-HSA-2122947|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-4411364|reactome:R-HSA-5687128|reactome:R-HSA-5689880|reactome:R-HSA-6785807|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8866911|reactome:R-HSA-8951430|reactome:R-HSA-9018519|reactome:R-HSA-9616222 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:CCk+p9FN7JV6cTmJDlin2hRp1tg9606 rigid:TIxoPtC6gQitHf0hKMgOXVXk/5s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q12857 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-2795262|uniprotkb:Q8TA97|uniprotkb:Q9H3X9|uniprotkb:Q9P2A9|uniprotkb:B4DRJ3|uniprotkb:B4DS53|uniprotkb:F5H0R0|uniprotkb:F8W8W3|ensembl:ENSP00000384523 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:nfia_human(display_long)|uniprotkb:NFIA(gene name)|psi-mi:NFIA(display_short)|uniprotkb:KIAA1439(gene name synonym)|uniprotkb:Nuclear factor I/A(gene name synonym)|uniprotkb:CCAAT-box-binding transcription factor(gene name synonym)|uniprotkb:TGGCA-binding protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285767|imex:IM-26899-567 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_001128145.1|refseq:NP_001138983.1|refseq:NP_001138984.1|refseq:NP_005586.1|go:"GO:0006260"(DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0019079"(viral genome replication)|go:"GO:0030054"(cell junction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060074"(synapse maturation)|go:"GO:0072189"(ureter development)|interpro:IPR000647(CTF/NF-I)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR019548|interpro:IPR019739|interpro:IPR020604|mint:Q12857|reactome:R-HSA-73980|reactome:R-HSA-749476|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000162599(gene)|ensembl:ENST00000403491(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus) - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:4NbJmVObdwd3x/axUAh/ESky6Yw9606 rigid:8gGm86m7PteL2sIjMg5v+CYuPOY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:P18669 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-717905|uniprotkb:Q9BWC0|ensembl:ENSP00000359991 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:pgam1_human(display_long)|uniprotkb:Phosphoglycerate mutase isozyme B(gene name synonym)|uniprotkb:BPG-dependent PGAM 1(gene name synonym)|uniprotkb:PGAM1(gene name)|psi-mi:PGAM1(display_short)|uniprotkb:CDABP0006(orf name)|uniprotkb:PGAMA(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285773|imex:IM-26899-351 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_002620.1|ensembl:ENSG00000171314(gene)|ensembl:ENST00000334828(transcript)|go:"GO:0004082"(bisphosphoglycerate mutase activity)|go:"GO:0004619"(phosphoglycerate mutase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006096"(glycolytic process)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043456"(regulation of pentose-phosphate shunt)|go:"GO:0045730"(respiratory burst)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001345(Phosphoglycerate/bisphosphoglycerate mutase)|interpro:IPR005952(Phosphoglycerate mutase 1)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR029033|mint:P18669|rcsb pdb:1LJD|rcsb pdb:1YFK|rcsb pdb:1YJX|rcsb pdb:4GPI|rcsb pdb:4GPZ|rcsb pdb:5Y2I|rcsb pdb:5Y2U|rcsb pdb:5Y35|rcsb pdb:5Y64|rcsb pdb:5Y65|rcsb pdb:5ZRM|rcsb pdb:5ZS8|rcsb pdb:6ISN|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70263 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:GI6jwRrX08owCyzx8KnRU8QP2rg9606 rigid:gk3GFq1Q5rHzmAMxs1b1M/d2+lk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q15181 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-712298|ensembl:ENSP00000362329|uniprotkb:Q2M348|uniprotkb:Q5SQT7|uniprotkb:Q6P7P4|uniprotkb:Q9UQJ5|uniprotkb:Q9Y5B1 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:ipyr_human(display_long)|uniprotkb:Pyrophosphate phospho-hydrolase(gene name synonym)|uniprotkb:PPA1(gene name)|psi-mi:PPA1(display_short)|uniprotkb:IOPPP(gene name synonym)|uniprotkb:PP(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285797|imex:IM-26899-665 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 ensembl:ENSG00000180817(gene)|ensembl:ENST00000373232(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004427"(inorganic diphosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008162(Inorganic pyrophosphatase)|interpro:IPR036649|mint:Q15181|rcsb pdb:6C45|rcsb pdb:7BTN|rcsb pdb:7CMO|reactome:R-HSA-379716|reactome:R-HSA-71737|refseq:NP_066952.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:1094gn9aeisgfDUhIroRn2iqom49606 rigid:M6EgQ2oJYwwvK82GNwBY+QTAZp0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q5JRX3 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-2432778|uniprotkb:B4E0J8|uniprotkb:E7ES23|uniprotkb:B3KMJ6|uniprotkb:O95204|uniprotkb:Q2M2G6|uniprotkb:Q4VBR1|uniprotkb:Q5JRW7|uniprotkb:Q7L5Z7|uniprotkb:Q9BSI6|uniprotkb:Q9BVJ5|uniprotkb:Q9UPP8|uniprotkb:C9JSL2|ensembl:ENSP00000224949 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:prep_human(display_long)|uniprotkb:PITRM1(gene name)|psi-mi:PITRM1(display_short)|uniprotkb:KIAA1104(gene name synonym)|uniprotkb:MP1(gene name synonym)|uniprotkb:Pitrilysin metalloproteinase 1(gene name synonym)|uniprotkb:PREP(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285779|imex:IM-26899-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_001229236.1|refseq:NP_001229238.1|refseq:NP_055704.2|dip:DIP-52900N|ensembl:ENSG00000107959(gene)|ensembl:ENST00000224949(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006508"(proteolysis)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016485"(protein processing)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|interpro:IPR013578(Peptidase M16C associated)|mint:Q5JRX3|rcsb pdb:4L3T|rcsb pdb:4NGE|rcsb pdb:4RPU|reactome:R-HSA-1268020 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:1kEY/XJB5fwgNRoM9u9ZGT+VrS09606 rigid:DFGF+X6QcG/CnhozoDIq70n0zhE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:O00469 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-1047459|uniprotkb:Q59ED2|uniprotkb:Q8N170|intact:EBI-2559757|uniprotkb:B3KWS3|ensembl:ENSP00000353170 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:plod2_human(display_long)|uniprotkb:Lysyl hydroxylase 2(gene name synonym)|uniprotkb:PLOD2(gene name)|psi-mi:PLOD2(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285785|imex:IM-26899-353 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_000926.2|refseq:NP_891988.1|ensembl:ENSG00000152952(gene)|ensembl:ENST00000360060(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008475"(procollagen-lysine 5-dioxygenase activity)|go:"GO:0017185"(peptidyl-lysine hydroxylation)|go:"GO:0030867"(rough endoplasmic reticulum membrane)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0046947"(hydroxylysine biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001006(Procollagen-lysine 5-dioxygenase)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|interpro:IPR029044|mint:O00469|reactome:R-HSA-1650814 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:sNgFtZzNoKBCz7KUhTBfMG/xxas9606 rigid:L0f/mUh/8UKd58zRdHFTUhc0prc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:P54277 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-2893308|ensembl:ENSP00000406490|uniprotkb:D3DPI1|uniprotkb:Q4VAL4|uniprotkb:Q5FBZ8|uniprotkb:Q5FBZ3|uniprotkb:Q5FBZ6 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:pms1_human(display_long)|uniprotkb:PMS1(gene name)|psi-mi:PMS1(display_short)|uniprotkb:PMSL1(gene name synonym)|uniprotkb:DNA mismatch repair protein PMS1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285791|imex:IM-26899-133 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_000525.1|ensembl:ENSG00000064933(gene)|ensembl:ENST00000441310(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006298"(mismatch repair)|go:"GO:0019899"(enzyme binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0042493"|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR020568|interpro:IPR036890|interpro:IPR036910|interpro:IPR038973|mint:P54277|rcsb pdb:2CS1|refseq:NP_001276337.1|refseq:XP_016859833.1|refseq:XP_016859837.1|refseq:NP_001121616.1|refseq:NP_001121615.1|refseq:NP_001307974.1|refseq:NP_001307975.1|refseq:NP_001307976.1|refseq:NP_001307977.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:URnCj+2/Inh5Wsc1UFHYh1gowFQ9606 rigid:SRUUDuspvdZQdiC6hEi0tsK9OiM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q14157 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-347762|uniprotkb:Q5VU75|uniprotkb:Q5VU76|uniprotkb:Q9BTU3|uniprotkb:Q9UGL2|uniprotkb:Q9UGL3|uniprotkb:Q9UGL5|uniprotkb:B4E0U8|uniprotkb:Q9UGL4|ensembl:ENSP00000355343|ensembl:ENSP00000389445 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:ubp2l_human(display_long)|uniprotkb:UBAP2L(gene name)|psi-mi:UBAP2L(display_short)|uniprotkb:Protein NICE-4(gene name synonym)|uniprotkb:KIAA0144(gene name synonym)|uniprotkb:NICE4(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285893|imex:IM-26899-359 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:XP_011508518.1|refseq:NP_001120792.1|refseq:NP_055662.3|refseq:NP_001274744.1|refseq:NP_001274745.1|refseq:XP_005245731.1|refseq:XP_016858467.1|refseq:XP_016858468.1|refseq:XP_016858475.1|refseq:XP_016858476.1|refseq:XP_016858478.1|refseq:XP_016858479.1|ensembl:ENSG00000143569(gene)|ensembl:ENST00000361546(transcript)|ensembl:ENST00000428931(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0031519"(PcG protein complex)|go:"GO:0034063"(stress granule assembly)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR022166|mint:Q14157 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:4iKY4hJOHGSyOOt8zfPhkeyth6Q9606 rigid:314Fv6TjrWvv/afKL9QU7GHJz3c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q8IYM9 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-954123|ensembl:ENSP00000369299|uniprotkb:Q15521|uniprotkb:Q05CQ0 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:tri22_human(display_long)|uniprotkb:RING finger protein 94(gene name synonym)|uniprotkb:50 kDa-stimulated trans-acting factor(gene name synonym)|uniprotkb:Staf-50(gene name synonym)|uniprotkb:Tripartite motif-containing protein 22(gene name synonym)|uniprotkb:TRIM22(gene name)|psi-mi:TRIM22(display_short)|uniprotkb:RNF94(gene name synonym)|uniprotkb:STAF50(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM22(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285887|imex:IM-26899-137 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 ensembl:ENSG00000132274(gene)|ensembl:ENST00000379965(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009615"(response to virus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0015030"(Cajal body)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR035827|interpro:IPR043136|mint:Q8IYM9|reactome:R-HSA-877300|go:"GO:0051607"(defense response to virus)|refseq:NP_001186502.1|refseq:NP_006065.2 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:8CNTleevg3ll6+eu/3p28ysv1M09606 rigid:Vq/dJV32mwNW06U89e/H8cOiXgg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q92547 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-308302|uniprotkb:Q7LGC1|uniprotkb:Q9UEB9|uniprotkb:B7Z7W8|ensembl:ENSP00000260810 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:topb1_human(display_long)|uniprotkb:KIAA0259(gene name synonym)|uniprotkb:TOPBP1(gene name)|psi-mi:TOPBP1(display_short)|uniprotkb:DNA topoisomerase II-binding protein 1(gene name synonym)|uniprotkb:DNA topoisomerase II-beta-binding protein 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285881|imex:IM-26899-465 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_008958.2|ensembl:ENSG00000163781(gene)|ensembl:ENST00000260810(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001357(BRCT)|interpro:IPR035960|interpro:IPR036420|interpro:IPR044737|mint:Q92547|rcsb pdb:1WF6|rcsb pdb:2XNH|rcsb pdb:2XNK|rcsb pdb:3AL2|rcsb pdb:3AL3|rcsb pdb:3JVE|rcsb pdb:3OLC|rcsb pdb:3PD7|rcsb pdb:3UEN|rcsb pdb:3UEO|rcsb pdb:6RML|rcsb pdb:6RMM|rcsb pdb:7CMZ|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|refseq:XP_016861125.1|dip:DIP-24263N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:QlPHW0dd/u8bQgAUNVnsjcsO+Bk9606 rigid:wlEgMLqbmRnZqB7UQK6khm4gbmo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:P49746 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-2530931|uniprotkb:B1AVR8|uniprotkb:Q8WV34|ensembl:ENSP00000357362|uniprotkb:B4DQ20 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:tsp3_human(display_long)|uniprotkb:THBS3(gene name)|psi-mi:THBS3(display_short)|uniprotkb:TSP3(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285875|imex:IM-26899-571 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 reactome:R-HSA-186797|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003367(Thrombospondin type 3 repeat)|interpro:IPR008859(Thrombospondin, C-terminal)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017897|interpro:IPR018097|interpro:IPR024665|interpro:IPR028507|interpro:IPR028974|mint:P49746|ensembl:ENSG00000169231(gene)|ensembl:ENST00000368378(transcript)|go:"GO:0003417"(growth plate cartilage development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008201"(heparin binding)|go:"GO:0043931"(ossification involved in bone maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060346"(bone trabecula formation)|refseq:NP_009043.1|refseq:NP_001239536.1|refseq:NP_001239537.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:v41BoGII7o5DU7gHTLSm328R+9w9606 rigid:Az31C67DUmUBiNtXKBxNcqH2JKE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q15431 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-2555298|uniprotkb:Q5VXJ6|uniprotkb:O14963|ensembl:ENSP00000358531|ensembl:ENSP00000358535|ensembl:ENSP00000480997 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:sycp1_human(display_long)|uniprotkb:SCP1(gene name synonym)|uniprotkb:Cancer/testis antigen 8(gene name synonym)|uniprotkb:SYCP1(gene name)|psi-mi:SYCP1(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285869|imex:IM-26899-757 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_003167.2|refseq:NP_001269470.1|ensembl:ENSG00000198765(gene)|ensembl:ENST00000369518(transcript)|ensembl:ENST00000369522(transcript)|ensembl:ENST00000618516(transcript)|go:"GO:0000711"(meiotic DNA repair synthesis)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000801"(central element)|go:"GO:0000802"(transverse filament)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007283"(spermatogenesis)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0035092"(sperm DNA condensation)|go:"GO:0051026"(chiasma assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051301"(cell division)|go:"GO:0051878"(lateral element assembly)|interpro:IPR008827(Synaptonemal complex 1)|mint:Q15431|rcsb pdb:4YTO|rcsb pdb:6F5X|rcsb pdb:6F62|rcsb pdb:6F63|rcsb pdb:6F64|reactome:R-HSA-1221632|refseq:XP_006710922.1|refseq:XP_016857673.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:jvR0EZ6l7soQDldrQCBEbGcueB89606 rigid:pkA1rTnae9liyKAcRd8nTiVx2sc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NHS9 uniprotkb:Q83D60 intact:EBI-7067260|ensembl:ENSP00000380354|ensembl:ENSP00000459329|ensembl:ENSP00000459580|ensembl:ENSP00000460187|intact:MINT-8201601|uniprotkb:D3DTI9|uniprotkb:J3KN63|uniprotkb:Q96JT4|uniprotkb:Q969H3|uniprotkb:B4DXB1 intact:EBI-21285556|ensemblbacteria:AAO90413 psi-mi:spt22_human(display_long)|uniprotkb:SPATA22(gene name)|psi-mi:SPATA22(display_short)|uniprotkb:Testis development protein NYD-SP20(gene name synonym) psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285863|imex:IM-26899-569 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308265.1|refseq:NP_001308266.1|ensembl:ENSG00000141255(gene)|ensembl:ENST00000397168(transcript)|ensembl:ENST00000572969(transcript)|ensembl:ENST00000573128(transcript)|ensembl:ENST00000575375(transcript)|go:"GO:0000711"(meiotic DNA repair synthesis)|go:"GO:0005694"(chromosome)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007276"(gamete generation)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060631"(regulation of meiosis I)|interpro:IPR033536|mint:Q8NHS9|refseq:NP_001164167.1|refseq:NP_001164169.1|refseq:NP_115987.2|refseq:NP_001164168.1|refseq:NP_001164166.1|refseq:NP_001164170.1 ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 - comment:mint|comment:homomint - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:6SGHXJywVk383ITHBKxLAhAfXuE9606 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rigid:a7X7uM+Q9RHwA4LqeZOYk7pxKi8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q8TCU3 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-21285839|ensembl:ENSP00000297524|uniprotkb:Q05C37|uniprotkb:Q08AH9|uniprotkb:Q96N84 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:s7a13_human(display_long)|uniprotkb:SLC7A13(gene name)|psi-mi:SLC7A13(display_short)|uniprotkb:AGT1(gene name synonym)|uniprotkb:XAT2(gene name synonym)|uniprotkb:Sodium-independent aspartate/glutamate transporter 1(gene name synonym)|uniprotkb:X-amino acid transporter 2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285857|imex:IM-26899-357 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 ensembl:ENSG00000164893(gene)|ensembl:ENST00000297524(transcript)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0015811"(L-cystine transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR002293(Amino acid/polyamine transporter I)|mint:Q8TCU3|refseq:NP_620172.2 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:W8HPrBO1TnsueOONPohwDYH1z9c9606 rigid:6rq0Axz9Ukd0YVUIYvoIyUiulYM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q96HL8 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-722667|uniprotkb:B7WPL6|intact:EBI-749123|uniprotkb:A8K8E7|uniprotkb:Q9H5X4|uniprotkb:Q9Y3V5|uniprotkb:Q8NEL2|uniprotkb:B7WNJ4|intact:EBI-28983457|ensembl:ENSP00000348471|ensembl:ENSP00000384269 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:sh3y1_human(display_long)|uniprotkb:SH3YL1(gene name)|psi-mi:SH3YL1(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285833|imex:IM-26899-355 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_001269611.1|refseq:NP_001269616.1|refseq:NP_001153069.1|refseq:NP_056492.2|ensembl:ENSP00000348471|ensembl:ENST00000402632|ensembl:ENSP00000384910|ensembl:ENST00000403657|ensembl:ENST00000403658|ensembl:ENSP00000383928|ensembl:ENST00000403712|ensembl:ENSP00000384276|ensembl:ENSP00000384269|ensembl:ENST00000626873|ensembl:ENSP00000485824|ensembl:ENSP00000385668|ensembl:ENSG00000035115(gene)|ensembl:ENST00000356150(transcript)|ensembl:ENST00000405430(transcript)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:1900027"(regulation of ruffle assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR007461(Protein of unknown function DUF500)|interpro:IPR033643|interpro:IPR035511|interpro:IPR036028|mint:Q96HL8|rcsb pdb:2D8H - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:xet0gjUb2Hgt8wCxwQyMs2AYmig9606 rigid:/5ucmPKKful3gjzVtVn6P1YdBvo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:P62241 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-351811|uniprotkb:Q6IRL7|uniprotkb:P09058|ensembl:ENSP00000379888 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:rs8_human(display_long)|uniprotkb:RPS8(gene name)|psi-mi:RPS8(display_short)|uniprotkb:Small ribosomal subunit protein eS8(gene name synonym)|uniprotkb:OK/SW-cl.83(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285827|imex:IM-26899-671 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_001003.1|ensembl:ENSG00000142937(gene)|ensembl:ENST00000396651(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001047(Ribosomal protein S8e)|interpro:IPR018283|interpro:IPR022309|interpro:IPR042563|mint:P62241|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:6G5H|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975957|reactome:R-HSA-975956 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:3rpCBdQyRWR+TCKnupbnCp30jKE9606 rigid:fGOWwgb/IxAapbECVrbiMVW7pOE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:P49802 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-1754797|uniprotkb:Q8TD66|uniprotkb:Q8TD67|uniprotkb:Q9UNU7|uniprotkb:Q9Y6B9|uniprotkb:Q5T3H4|uniprotkb:Q8WW09|ensembl:ENSP00000404399 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:rgs7_human(display_long)|uniprotkb:RGS7(gene name)|psi-mi:RGS7(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285821|imex:IM-26899-669 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_001269702.1|refseq:NP_001269704.1|refseq:NP_001269707.1|refseq:NP_002915.3|refseq:XP_005273275.1|dip:DIP-40869N|interpro:IPR036390|interpro:IPR040759|mint:P49802|rcsb pdb:2A72|rcsb pdb:2D9J|reactome:R-HSA-418594|reactome:R-HSA-6814122|interpro:IPR036388|go:"GO:0043547"(positive regulation of GTPase activity)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR015898(G-protein, gamma-like subunit)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR036284|ensembl:ENSG00000182901(gene)|ensembl:ENST00000440928(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR036305 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:epeNPVu00d27S9hlaKto1/bKwhI9606 rigid:HBFX7OQnp4clvuCTuIcXYrvP/tA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q14671 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-948453|ensembl:ENSP00000257075|uniprotkb:Q5VXY7|uniprotkb:Q9HAN1|intact:EBI-2842591|uniprotkb:E9PCJ0|uniprotkb:Q53HH5|uniprotkb:B4DG92|uniprotkb:A8K6W4|uniprotkb:D3DPN3 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:pum1_human(display_long)|uniprotkb:PUM1(gene name)|psi-mi:PUM1(display_short)|uniprotkb:KIAA0099(gene name synonym)|uniprotkb:PUMH1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285815|imex:IM-26899-667 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 ensembl:ENSG00000134644(gene)|ensembl:ENST00000257075(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035198"(miRNA binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0048863"(stem cell differentiation)|interpro:IPR033712|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060964"(regulation of gene silencing by miRNA)|go:"GO:0061157"(mRNA destabilization)|mint:Q14671|rcsb pdb:1IB2|rcsb pdb:1M8W|rcsb pdb:1M8X|rcsb pdb:1M8Y|rcsb pdb:1M8Z|rcsb pdb:2YJY|rcsb pdb:3BSB|rcsb pdb:3BSX|rcsb pdb:3Q0L|rcsb pdb:3Q0M|rcsb pdb:3Q0N|rcsb pdb:3Q0O|rcsb pdb:3Q0P|rcsb pdb:5YKH|rcsb pdb:5YKI|reactome:R-HSA-432722|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|refseq:NP_001018494.1|refseq:NP_055491.1|dip:DIP-29082N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:tGsSgrvQ/Ehnm3UC5IO4CHhCrFs9606 rigid:CuB1xthZtaiZAVDvZtWJcAkJ9t8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:P20618 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-372273|uniprotkb:Q9BWA8|ensembl:ENSP00000262193|uniprotkb:B5BU76 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:psb1_human(display_long)|uniprotkb:PSMB1(gene name)|psi-mi:PSMB1(display_short)|uniprotkb:PSC5(gene name synonym)|uniprotkb:Proteasome component C5(gene name synonym)|uniprotkb:Macropain subunit C5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C5(gene name synonym)|uniprotkb:Proteasome gamma chain(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285809|imex:IM-26899-135 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 ensembl:ENSG00000008018(gene)|ensembl:ENST00000262193(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|mint:P20618|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|refseq:NP_002784.1|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M2B|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5LF1|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4608870|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-983168|reactome:R-HSA-9604323|dip:DIP-31193N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:DfIS480BUnqbXus9/KoojdkWgw09606 rigid:OvG/fPP+B8r0IGfELYMtMxM1R6A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q9UNP9 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-591818|uniprotkb:Q3S611|uniprotkb:Q5TGA3|uniprotkb:O43634|uniprotkb:O43635|uniprotkb:Q32Q72|uniprotkb:Q5TGA0|uniprotkb:Q5TGA2|uniprotkb:Q9UIZ5|uniprotkb:B2R971|ensembl:ENSP00000312769 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:ppie_human(display_long)|uniprotkb:Cyclophilin E(gene name synonym)|uniprotkb:Cyclophilin-33(gene name synonym)|uniprotkb:PPIE(gene name)|psi-mi:PPIE(display_short)|uniprotkb:CYP33(gene name synonym)|uniprotkb:Rotamase E(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285803|imex:IM-26899-243 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_006103.1|refseq:NP_982281.1|refseq:NP_001181936.1|refseq:XP_016855540.1|dip:DIP-34757N|ensembl:ENSG00000084072(gene)|ensembl:ENST00000324379(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR016304(Peptidyl-prolyl cis-trans isomerase E)|interpro:IPR020892|interpro:IPR029000|interpro:IPR034168|interpro:IPR035979|mint:Q9UNP9|rcsb pdb:1ZMF|rcsb pdb:2CQB|rcsb pdb:2KU7|rcsb pdb:2KYX|rcsb pdb:2R99|rcsb pdb:3LPY|rcsb pdb:3MDF|rcsb pdb:3UCH|rcsb pdb:5MQF|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6798695|reactome:R-HSA-72163 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:zMkadgyIl5RwvoD3h3vetTqLjg49606 rigid:Ys7GfTvJwmBH8iSN/2XhiHKXDjk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q9P1Z0 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-2564133|uniprotkb:B3KVL6|uniprotkb:Q7Z697|uniprotkb:Q86XJ4|uniprotkb:Q8N4V8|ensembl:ENSP00000307858|ensembl:ENSP00000369973|ensembl:ENSP00000492232|ensembl:ENSP00000492616 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:zbtb4_human(display_long)|uniprotkb:ZBTB4(gene name)|psi-mi:ZBTB4(display_short)|uniprotkb:KIAA1538(gene name synonym)|uniprotkb:KAISO-like zinc finger protein 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285905|imex:IM-26899-759 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:XP_011522274.1|refseq:NP_001122305.1|refseq:NP_065950.2|ensembl:ENSG00000174282(gene)|ensembl:ENSG00000283868(gene)|ensembl:ENST00000311403(transcript)|ensembl:ENST00000380599(transcript)|ensembl:ENST00000639670(transcript)|ensembl:ENST00000639962(transcript)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0010428"(methyl-CpNpG binding)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9P1Z0|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|refseq:XP_006721626.1|refseq:XP_006721627.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:CZJEikI46aYaPyxTb/FJnxTD5eM9606 rigid:uMyEF4PrdCoItnK9/vnoDqCXt3Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:P40818 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-1050865|uniprotkb:Q2TB31|uniprotkb:Q7Z3U2|uniprotkb:Q86VA0|uniprotkb:Q8IWI7|ensembl:ENSP00000302239|ensembl:ENSP00000379721|uniprotkb:B4DKA8 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:ubp8_human(display_long)|uniprotkb:Ubiquitin-specific-processing protease 8(gene name synonym)|uniprotkb:Deubiquitinating enzyme 8(gene name synonym)|uniprotkb:USP8(gene name)|psi-mi:USP8(display_short)|uniprotkb:KIAA0055(gene name synonym)|uniprotkb:UBPY(gene name synonym)|uniprotkb:Ubiquitin isopeptidase Y(gene name synonym)|uniprotkb:Ubiquitin thioesterase 8(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285899|imex:IM-26899-361 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_001122082.1|refseq:NP_005145.3|refseq:NP_001269978.1|refseq:XP_011520495.1|ensembl:ENSG00000138592(gene)|ensembl:ENST00000307179(transcript)|ensembl:ENST00000396444(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007032"(endosome organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030496"(midbody)|go:"GO:0031313"(extrinsic component of endosome membrane)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0043197"(dendritic spine)|go:"GO:0045296"(cadherin binding)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099576"(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR015063(Region of unknown function DUF1873)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|mint:P40818|rcsb pdb:1WHB|rcsb pdb:2A9U|rcsb pdb:2GFO|rcsb pdb:2GWF|rcsb pdb:3N3K|rcsb pdb:6F09|reactome:R-HSA-1358803|reactome:R-HSA-4641263|reactome:R-HSA-5689880|reactome:R-HSA-6807004|refseq:XP_006720824.1|dip:DIP-40365N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:hpBBzyA4lc9is80ZFJBr1fyEyOM9606 rigid:0Vs8kxSd2CKY+5GX/Y2v4KJnDBc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D09 uniprotkb:P20810 intact:EBI-21285965|ensemblbacteria:AAO90464 intact:EBI-1268770|uniprotkb:G5E9D3|uniprotkb:O95360|uniprotkb:Q96D08|uniprotkb:Q9H1Z5|uniprotkb:Q7Z4K0|intact:EBI-11042429|uniprotkb:B7Z468|uniprotkb:Q05DE8|uniprotkb:G5E946|ensembl:ENSP00000339914|ensembl:ENSP00000379158 psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name) psi-mi:ical_human(display_long)|uniprotkb:CAST(gene name)|psi-mi:CAST(display_short)|uniprotkb:Calpain inhibitor(gene name synonym)|uniprotkb:Sperm BS-17 component(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286001|imex:IM-26899-761 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90464(transcript)|ensemblbacteria:CBU_0937(gene)|refseq:NP_819950.2|mint:Q83D09 refseq:NP_001035905.1|refseq:XP_006714759.1|refseq:XP_006714766.1|refseq:NP_001271141.1|refseq:XP_006714764.1|refseq:NP_001035906.1|refseq:NP_001035907.1|refseq:NP_001035908.1|refseq:NP_001035909.1|refseq:NP_001317560.1|refseq:NP_001741.4|refseq:XP_016865402.1|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|interpro:IPR001259(Proteinase inhibitor I27, calpastatin)|interpro:IPR026998|mint:P20810|reactome:R-HSA-1474228|reactome:R-HSA-8862803|go:"GO:1990709"(presynaptic active zone organization)|ensembl:ENSG00000153113(gene)|ensembl:ENST00000341926(transcript)|ensembl:ENST00000395813(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0010859"(calcium-dependent cysteine-type endopeptidase inhibitor activity)|go:"GO:0016020"(membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0097340"(inhibition of cysteine-type endopeptidase activity)|refseq:NP_775083.1|refseq:XP_006714767.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377 rogid:sDc8/o13gLhr18fYsz/grYg13Lo9606 rigid:9tdBSrqJW1FSM3w4OpfYVWphAxc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D09 uniprotkb:Q1RMZ1 intact:EBI-21285965|ensemblbacteria:AAO90464 intact:EBI-21285976|ensembl:ENSP00000297145|uniprotkb:Q8N3D0|uniprotkb:Q96MV7 psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name) psi-mi:samtr_human(display_long)|uniprotkb:BMT2(gene name)|psi-mi:BMT2(display_short)|uniprotkb:C7orf60(gene name synonym)|uniprotkb:SAMTOR(gene name synonym)|uniprotkb:Probable methyltransferase BMT2 homolog(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285995|imex:IM-26899-141 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90464(transcript)|ensemblbacteria:CBU_0937(gene)|refseq:NP_819950.2|mint:Q83D09 ensembl:ENSG00000164603(gene)|ensembl:ENST00000297145(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016433"("rRNA (adenine) methyltransferase activity")|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1904262"(negative regulation of TORC1 signaling)|interpro:IPR021867|interpro:IPR029063|mint:Q1RMZ1|reactome:R-HSA-9639288|refseq:NP_689769.2 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377 rogid:l8SMJSLuDy0JmAPhAdrG0PdFORI9606 rigid:Tkl5PTtSPT5R0ZQlfPWkt8gvSGo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D09 uniprotkb:P00325 intact:EBI-21285965|ensemblbacteria:AAO90464 intact:EBI-2838677|uniprotkb:Q4ZGI9|uniprotkb:Q13711|uniprotkb:Q96KI7|uniprotkb:A8MYN5|uniprotkb:B4DRS9|uniprotkb:B4DVC3|ensembl:ENSP00000306606 psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name) psi-mi:adh1b_human(display_long)|uniprotkb:ADH1B(gene name)|psi-mi:ADH1B(display_short)|uniprotkb:ADH2(gene name synonym)|uniprotkb:Alcohol dehydrogenase subunit beta(gene name synonym)|uniprotkb:Alcohol dehydrogenase 1B(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285970|imex:IM-26899-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90464(transcript)|ensemblbacteria:CBU_0937(gene)|refseq:NP_819950.2|mint:Q83D09 refseq:NP_000659.2|refseq:NP_001273579.1|ensembl:ENSG00000196616(gene)|ensembl:ENST00000305046(transcript)|go:"GO:0001523"(retinoid metabolic process)|go:"GO:0004745"(NAD-retinol dehydrogenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006069"(ethanol oxidation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042572"(retinol metabolic process)|go:"GO:0042573"(retinoic acid metabolic process)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR020843|interpro:IPR036291|mint:P00325|rcsb pdb:1DEH|rcsb pdb:1HDX|rcsb pdb:1HDY|rcsb pdb:1HDZ|rcsb pdb:1HSZ|rcsb pdb:1HTB|rcsb pdb:1U3U|rcsb pdb:1U3V|rcsb pdb:3HUD|reactome:R-HSA-71384|go:"GO:0004024"(alcohol dehydrogenase activity, zinc-dependent) - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377 rogid:RiC6sQ33gHB3PzAAoSYqseh/XLE9606 rigid:cZYnwqjbPoxJre04OIfpnFuBsAk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D57 uniprotkb:Q8IYB9 intact:EBI-21285947|ensemblbacteria:AAO90416 intact:EBI-2682172|ensembl:ENSP00000477392|uniprotkb:Q7Z3I0|intact:EBI-12135433 psi-mi:q83d57_coxbu(display_long)|uniprotkb:CBU_0885(locus name) psi-mi:zn595_human(display_long)|uniprotkb:ZNF595(gene name)|psi-mi:ZNF595(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285959|imex:IM-26899-365 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90416(transcript)|ensemblbacteria:CBU_0885(gene)|refseq:NP_819902.2|refseq:WP_010957867.1|mint:Q83D57 refseq:NP_001272981.1|refseq:NP_001272982.1|refseq:NP_001272983.1|refseq:NP_872330.1|ensembl:ENSG00000272602(gene)|ensembl:ENST00000610261(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|mint:Q8IYB9|reactome:R-HSA-212436 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:nmEtkvTQxaroeu4VK6t674RWCg0227377 rogid:bw/THTDnw6TEGPE5oJ2kXLiw5Mg9606 rigid:BGw4Xg1wlS9MLjV2UUu0oaQ41is false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q9NZV7 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-11962760|ensembl:ENSP00000468984|ensembl:ENSP00000470326|ensembl:ENSP00000472306|ensembl:ENSP00000486502|uniprotkb:Q2M3K1 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:zim2_human(display_long)|uniprotkb:ZIM2(gene name)|psi-mi:ZIM2(display_short)|uniprotkb:ZNF656(gene name synonym)|uniprotkb:Zinc finger protein 656(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285911|imex:IM-26899-673 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 ensembl:ENSG00000269699(gene)|ensembl:ENST00000593711(transcript)|ensembl:ENST00000599935(transcript)|ensembl:ENST00000601070(transcript)|ensembl:ENST00000629319(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|mint:Q9NZV7|reactome:R-HSA-212436|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|refseq:NP_001139798.1|refseq:NP_001139799.1|refseq:NP_056178.3 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:m5QQuE7S1ZDsqhxEzm9Z1z80i089606 rigid:46arGFwUjOYd6bZZufX7Z2twebo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q6P1N2 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-21285736 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:q6p1n2_human(display_long)|uniprotkb:MTIF2(gene name)|psi-mi:MTIF2(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285941|imex:IM-26899-363 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|refseq:NP_001005369.1|refseq:NP_002444.2|interpro:IPR027417|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR015760(Translation initiation factor 2 related)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|mint:Q6P1N2|interpro:IPR044145 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:1tWvOfEeLJfg31GeKiTLztjnehU9606 rigid:rAy/j8Q5yofJ+dX+Dhg/xzq5dGg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q7Z4V0 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-11962468|ensembl:ENSP00000354663|ensembl:ENSP00000387546|ensembl:ENSP00000406934|ensembl:ENSP00000412363|uniprotkb:A2A3J4|uniprotkb:A8K9L5|uniprotkb:Q5T426|uniprotkb:Q658Q4|uniprotkb:Q6ZN65 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:zn438_human(display_long)|uniprotkb:ZNF438(gene name)|psi-mi:ZNF438(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285935|imex:IM-26899-245 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 ensembl:ENSG00000183621(gene)|ensembl:ENST00000361310(transcript)|ensembl:ENST00000413025(transcript)|ensembl:ENST00000436087(transcript)|ensembl:ENST00000442986(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q7Z4V0|refseq:NP_001137238.1|refseq:NP_001137239.1|refseq:NP_001137240.1|refseq:NP_001137241.1|refseq:NP_001137242.1|refseq:NP_001137243.1|refseq:NP_877432.1|refseq:XP_006717456.1|refseq:XP_006717459.1|refseq:XP_006717461.1|refseq:XP_006717462.1|refseq:XP_011517673.1|refseq:XP_011517674.1|refseq:XP_011517675.1|refseq:XP_011517676.1|refseq:XP_011517678.1|refseq:XP_011517679.1|refseq:XP_016871353.1|refseq:XP_016871354.1|refseq:XP_016871355.1|refseq:XP_016871356.1|refseq:XP_016871357.1|refseq:XP_016871358.1|refseq:XP_016871359.1|refseq:XP_016871360.1|refseq:XP_016871361.1|refseq:XP_016871362.1|refseq:XP_016871363.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:QreFTL8bKUgoRzL37basyvBZTSk9606 rigid:S5dMrzqIKsTeOTjxPkyE0WN7w6E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q9GZX5 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-396421|uniprotkb:Q9HAQ4|uniprotkb:Q96G73|ensembl:ENSP00000243644 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:zn350_human(display_long)|uniprotkb:Zinc finger protein ZBRK1(gene name synonym)|uniprotkb:Zinc finger and BRCA1-interacting protein with a KRAB domain 1(gene name synonym)|uniprotkb:KRAB zinc finger protein ZFQR(gene name synonym)|uniprotkb:ZNF350(gene name)|psi-mi:ZNF350(display_short)|uniprotkb:ZBRK1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285929|imex:IM-26899-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_067645.3|ensembl:ENSG00000256683(gene)|refseq:XP_016882587.1|refseq:XP_016882588.1|refseq:XP_016882589.1|ensembl:ENST00000243644(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|mint:Q9GZX5|reactome:R-HSA-212436|reactome:R-HSA-3899300 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:n3L44uqErawnnBhZCDI2B7hnZxQ9606 rigid:LZqHk4sRw42KCtphLSMo6D+2tCs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q13360 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-3921570|uniprotkb:Q96ER2|ensembl:ENSP00000468531|uniprotkb:B4DY57|uniprotkb:I3L0I4|uniprotkb:E9PDG0 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:zn177_human(display_long)|uniprotkb:ZNF177(gene name)|psi-mi:ZNF177(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285923|imex:IM-26899-677 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_001166121.1|refseq:NP_003442.2|ensembl:ENSG00000188629(gene)|ensembl:ENST00000589262(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0072562"(blood microparticle)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|mint:Q13360|refseq:NP_001189354.1|refseq:NP_001166122.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:AQY71Gzch2ezw8lEB06fROw3QjM9606 rigid:zS+rsNK8Q63/Uyej29KEtvI/dro false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q9UBW7 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-2797576|uniprotkb:Q5W0T3|uniprotkb:O43434|uniprotkb:O43212|uniprotkb:Q5W0Q4|uniprotkb:Q9UEU2|uniprotkb:Q9H538|uniprotkb:Q9H0V5|uniprotkb:Q8NE39|uniprotkb:Q63HP0|uniprotkb:A6NI02|uniprotkb:A6NDG0|uniprotkb:O60898|ensembl:ENSP00000372324|ensembl:ENSP00000372327|ensembl:ENSP00000479904 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:zmym2_human(display_long)|uniprotkb:FIM(gene name synonym)|uniprotkb:RAMP(gene name synonym)|uniprotkb:ZNF198(gene name synonym)|uniprotkb:Fused in myeloproliferative disorders protein(gene name synonym)|uniprotkb:Rearranged in atypical myeloproliferative disorder protein(gene name synonym)|uniprotkb:Zinc finger protein 198(gene name synonym)|uniprotkb:ZMYM2(gene name)|psi-mi:ZMYM2(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285917|imex:IM-26899-675 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_001177893.1|refseq:NP_001177894.1|refseq:NP_003444.1|refseq:NP_932072.1|ensembl:ENSP00000372324|ensembl:ENSP00000372327|ensembl:ENSP00000479904|refseq:XP_005266577.1|ensembl:ENSG00000121741(gene)|ensembl:ENST00000382871(transcript)|ensembl:ENST00000382874(transcript)|ensembl:ENST00000610343(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR021893|mint:Q9UBW7|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-9703465|refseq:XP_016876218.1|refseq:XP_011533526.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:rsxYDcDeR5x2Lt3phHNYpCjf9KA9606 rigid:V1C2fEBWAyD9nhn6UKIoHHd5YVU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D57 uniprotkb:Q03188 intact:EBI-21285947|ensemblbacteria:AAO90416 intact:EBI-295799|uniprotkb:Q9P0M5|uniprotkb:Q8IW27|uniprotkb:Q6PIR0|ensembl:ENSP00000273853 psi-mi:q83d57_coxbu(display_long)|uniprotkb:CBU_0885(locus name) psi-mi:cenpc_human(display_long)|uniprotkb:CENPC(gene name)|psi-mi:CENPC(display_short)|uniprotkb:CENPC1(gene name synonym)|uniprotkb:Centromere autoantigen C(gene name synonym)|uniprotkb:Centromere protein C 1(gene name synonym)|uniprotkb:ICEN7(gene name synonym)|uniprotkb:Interphase centromere complex protein 7(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21285953|imex:IM-26899-139 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90416(transcript)|ensemblbacteria:CBU_0885(gene)|refseq:NP_819902.2|refseq:WP_010957867.1|mint:Q83D57 refseq:NP_001803.2|ensembl:ENSG00000145241(gene)|ensembl:ENST00000273853(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0030496"(midbody)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR025974|interpro:IPR028052|interpro:IPR028386|interpro:IPR028931|mint:Q03188|rcsb pdb:5LSJ|rcsb pdb:5LSK|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:nmEtkvTQxaroeu4VK6t674RWCg0227377 rogid:wPrWsvQ3j7zVPWsgleGrsS8O5wA9606 rigid:RrBuDFSn1nyDQ12uYRZLns1Obmc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D09 uniprotkb:Q9P0M9 intact:EBI-21285965|ensemblbacteria:AAO90464 intact:EBI-5325236|ensembl:ENSP00000225969|uniprotkb:B2RE14 psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name) psi-mi:rm27_human(display_long)|uniprotkb:Mitochondrial large ribosomal subunit protein bL27m(gene name synonym)|uniprotkb:HSPC250(orf name)|uniprotkb:MRPL27(gene name)|psi-mi:MRPL27(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286073|imex:IM-26899-367 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90464(transcript)|ensemblbacteria:CBU_0937(gene)|refseq:NP_819950.2|mint:Q83D09 mint:Q9P0M9|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|ensembl:ENSG00000108826(gene)|ensembl:ENST00000225969(transcript)|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|rcsb pdb:6ZS9|rcsb pdb:6ZSA|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|rcsb pdb:6ZSB|interpro:IPR001684(Ribosomal protein L27)|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:NP_057588.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377 rogid:Tb7r8GeSkNdNN6aY2mvmTR4MFmc9606 rigid:ohyKnpKBA4F1sIsSdMMifTp6SfI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D09 uniprotkb:P45985 intact:EBI-21285965|ensemblbacteria:AAO90464 intact:EBI-447868|uniprotkb:D3DTS5|uniprotkb:Q5U0B8|uniprotkb:B2R7N7|uniprotkb:B3KYB2|uniprotkb:Q6FHX4|uniprotkb:Q6P9H2|uniprotkb:Q6PIE6|intact:EBI-28973354|ensembl:ENSP00000262445 psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name) psi-mi:mp2k4_human(display_long)|uniprotkb:JNK-activating kinase 1(gene name synonym)|uniprotkb:c-Jun N-terminal kinase kinase 1(gene name synonym)|uniprotkb:SAPK/ERK kinase 1(gene name synonym)|uniprotkb:MAP2K4(gene name)|psi-mi:MAP2K4(display_short)|uniprotkb:JNKK1(gene name synonym)|uniprotkb:MKK4(gene name synonym)|uniprotkb:PRKMK4(gene name synonym)|uniprotkb:SERK1(gene name synonym)|uniprotkb:MEK4(gene name synonym)|uniprotkb:MAPK/ERK kinase 4(gene name synonym)|uniprotkb:SKK1(gene name synonym)|uniprotkb:SEK1(gene name synonym)|uniprotkb:Stress-activated protein kinase kinase 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286067|imex:IM-26899-769 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90464(transcript)|ensemblbacteria:CBU_0937(gene)|refseq:NP_819950.2|mint:Q83D09 refseq:NP_003001.1|ensembl:ENSP00000262445|ensembl:ENST00000415385|ensembl:ENSP00000410402|refseq:NP_001268364.1|ensembl:ENST00000353533(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007254"(JNK cascade)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008545"(JUN kinase kinase activity)|go:"GO:0009611"(response to wounding)|go:"GO:0030424"(axon)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0043204"(perikaryon)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0072709"(cellular response to sorbitol)|go:"GO:0090398"(cellular senescence)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000672"(negative regulation of motor neuron apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P45985|rcsb pdb:3ALN|rcsb pdb:3ALO|rcsb pdb:3VUT|reactome:R-HSA-2559580|reactome:R-HSA-2871796|reactome:R-HSA-450321|reactome:R-HSA-5210891|reactome:R-HSA-5684264|ensembl:ENSG00000065559(gene) - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377 rogid:/ndhkIbnc9oTm68r4DwDUyfXDF89606 rigid:pYErYbsb8c3x/ROVjcoqCZMhkrM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D09 uniprotkb:P33908 intact:EBI-21285965|ensemblbacteria:AAO90464 intact:EBI-12586254|ensembl:ENSP00000357453|uniprotkb:E7EU32|uniprotkb:Q6P052|uniprotkb:Q9NU44|uniprotkb:Q9UJI3 psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name) psi-mi:ma1a1_human(display_long)|uniprotkb:MAN1A1(gene name)|psi-mi:MAN1A1(display_short)|uniprotkb:"Man(9)-alpha-mannosidase"(gene name synonym)|uniprotkb:Mannosidase alpha class 1A member 1(gene name synonym)|uniprotkb:Processing alpha-1,2-mannosidase IA(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286061|imex:IM-26899-469 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90464(transcript)|ensemblbacteria:CBU_0937(gene)|refseq:NP_819950.2|mint:Q83D09 ensembl:ENSG00000111885(gene)|ensembl:ENST00000368468(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004571"(mannosyl-oligosaccharide 1,2-alpha-mannosidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006491"(N-glycan processing)|go:"GO:0015923"(mannosidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904381"(Golgi apparatus mannose trimming)|go:"GO:1904382"(mannose trimming involved in glycoprotein ERAD pathway)|interpro:IPR001382(Glycoside hydrolase, family 47)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR036026|mint:P33908|reactome:R-HSA-6811438|reactome:R-HSA-964827|refseq:NP_005898.2 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377 rogid:fmBa7NZdVy2Ou9DtEO2K1/T0AHw9606 rigid:lKP3qZiuvxsy1ciDiiUCr5wzns4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D09 uniprotkb:Q8IUZ0 intact:EBI-21285965|ensemblbacteria:AAO90464 intact:EBI-9477875|uniprotkb:B7Z366|uniprotkb:G5E9T5|uniprotkb:Q9NXM6|uniprotkb:H0YLN4|uniprotkb:B3KVX1|uniprotkb:F5H1J4|ensembl:ENSP00000260382 psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name) psi-mi:lrc49_human(display_long)|uniprotkb:LRRC49(gene name)|psi-mi:LRRC49(display_short)|uniprotkb:Tubulin polyglutamylase complex subunit 4(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286055|imex:IM-26899-767 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90464(transcript)|ensemblbacteria:CBU_0937(gene)|refseq:NP_819950.2|mint:Q83D09 refseq:XP_011520017.1|refseq:XP_016877847.1|refseq:NP_001271286.1|refseq:NP_001185946.1|refseq:NP_001185947.1|refseq:NP_060161.2|go:"GO:0005874"(microtubule)|go:"GO:0036158"(outer dynein arm assembly)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|mint:Q8IUZ0|reactome:R-HSA-8955332|ensembl:ENSG00000137821(gene)|ensembl:ENST00000260382(transcript)|go:"GO:0005737"(cytoplasm) - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377 rogid:6e+i7lca3hMpmbOQuv8GkDVEfoM9606 rigid:ZrfgY0xDzQuabSkz8WGMt3E4mE0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D09 uniprotkb:P24530 intact:EBI-21285965|ensemblbacteria:AAO90464 intact:EBI-6624656|uniprotkb:A2A2Z8|uniprotkb:A8K3T4|uniprotkb:O15343|uniprotkb:Q59GB1|uniprotkb:Q5W0G9|uniprotkb:Q8NHM6|uniprotkb:Q8NHM7|uniprotkb:Q8NHM8|uniprotkb:Q8NHM9|uniprotkb:Q9UD23|uniprotkb:Q9UQK3|ensembl:ENSP00000487082|ensembl:ENSP00000493527|ensembl:ENSP00000493895|ensembl:ENSP00000494278 psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name) psi-mi:ednrb_human(display_long)|uniprotkb:EDNRB(gene name)|psi-mi:EDNRB(display_short)|uniprotkb:ETRB(gene name synonym)|uniprotkb:Endothelin receptor non-selective type(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286007|imex:IM-26899-763 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90464(transcript)|ensemblbacteria:CBU_0937(gene)|refseq:NP_819950.2|mint:Q83D09 refseq:NP_000106.1|refseq:NP_001116131.1|refseq:NP_001188326.1|refseq:NP_003982.1|ensembl:ENSG00000136160(gene)|ensembl:ENST00000475537(transcript)|ensembl:ENST00000646605(transcript)|ensembl:ENST00000646607(transcript)|ensembl:ENST00000646948(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004962"(endothelin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006885"(regulation of pH)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007399"(nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007497"(posterior midgut development)|go:"GO:0007568"(aging)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014043"(negative regulation of neuron maturation)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014826"(vein smooth muscle contraction)|go:"GO:0017046"(peptide hormone binding)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019934"(cGMP-mediated signaling)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031620"(regulation of fever generation)|go:"GO:0031702"(type 1 angiotensin receptor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032269"(negative regulation of cellular protein metabolic process)|go:"GO:0035645"(enteric smooth muscle cell differentiation)|go:"GO:0035810"(positive regulation of urine volume)|go:"GO:0035815"(positive regulation of renal sodium excretion)|go:"GO:0042045"(epithelial fluid transport)|go:"GO:0042310"(vasoconstriction)|go:"GO:0042311"(vasodilation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0048265"(response to pain)|go:"GO:0048484"(enteric nervous system development)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0060406"(positive regulation of penile erection)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:1990839"(response to endothelin)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000499(Endothelin receptor)|interpro:IPR001112(Endothelin B receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P24530|rcsb pdb:5GLH|rcsb pdb:5GLI|rcsb pdb:5X93|rcsb pdb:5XPR|rcsb pdb:6IGK|rcsb pdb:6IGL|rcsb pdb:6LRY|reactome:R-HSA-375276|reactome:R-HSA-416476 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377 rogid:EVPfuNkUH6NzN8Jo1EjipkRmqSU9606 rigid:i8kmD8Pap5xoboLJ4h4HvJ7WInk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D09 uniprotkb:Q8N3F9 intact:EBI-21285965|ensemblbacteria:AAO90464 intact:EBI-21286031|ensembl:ENSP00000315106|uniprotkb:Q86SM2 psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name) psi-mi:g137c_human(display_long)|uniprotkb:GPR137C(gene name)|psi-mi:GPR137C(display_short)|uniprotkb:TM7SF1L2(gene name synonym)|uniprotkb:Transmembrane 7 superfamily member 1-like 2 protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286043|imex:IM-26899-145 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90464(transcript)|ensemblbacteria:CBU_0937(gene)|refseq:NP_819950.2|mint:Q83D09 ensembl:ENSG00000180998(gene)|ensembl:ENST00000321662(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR029723|mint:Q8N3F9|refseq:NP_001093122.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377 rogid:VAwg00VU+uorrcXewn8A2oJYV6E9606 rigid:lg36fVrx0VHPxSnKD1qkyL6O2uw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D09 uniprotkb:Q9Y680 intact:EBI-21285965|ensemblbacteria:AAO90464 intact:EBI-3918971|uniprotkb:Q96DA4|uniprotkb:Q9Y6B0|uniprotkb:Q86U65|uniprotkb:Q6V3B2|uniprotkb:Q4ZG70|ensembl:ENSP00000413152 psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name) psi-mi:fkbp7_human(display_long)|uniprotkb:FKBP7(gene name)|psi-mi:FKBP7(display_short)|uniprotkb:FKBP23(gene name synonym)|uniprotkb:23 kDa FK506-binding protein(gene name synonym)|uniprotkb:FK506-binding protein 7(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:UNQ670/PRO1304(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286025|imex:IM-26899-765 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90464(transcript)|ensemblbacteria:CBU_0937(gene)|refseq:NP_819950.2|mint:Q83D09 refseq:NP_001128684.1|refseq:NP_851939.1|ensembl:ENSG00000079150(gene)|ensembl:ENST00000424785(transcript)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005528"(FK506 binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0018208"(peptidyl-proline modification)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q9Y680 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377 rogid:HJ80Z7OSdidxr1a/p1IYSkVMGGY9606 rigid:tKt1ILLay6oHU46BKrOmRLfp02U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D09 uniprotkb:Q32MH5 intact:EBI-21285965|ensemblbacteria:AAO90464 intact:EBI-2866142|uniprotkb:Q4G0R7|uniprotkb:Q32MH6|uniprotkb:Q5XJ16|uniprotkb:Q9P2H7|uniprotkb:Q9NV24|uniprotkb:A8KA52|uniprotkb:Q6PDA3|uniprotkb:B4DEP5|uniprotkb:B4DF40|uniprotkb:F5H8G0|ensembl:ENSP00000261844|ensembl:ENSP00000484641 psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name) psi-mi:f214a_human(display_long)|uniprotkb:FAM214A(gene name)|psi-mi:FAM214A(display_short)|uniprotkb:KIAA1370(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286019|imex:IM-26899-247 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90464(transcript)|ensemblbacteria:CBU_0937(gene)|refseq:NP_819950.2|mint:Q83D09 refseq:NP_001273424.1|refseq:XP_011520091.1|refseq:NP_062546.2|refseq:XP_005254604.1|refseq:XP_005254605.1|ensembl:ENSG00000047346(gene)|ensembl:ENST00000261844(transcript)|ensembl:ENST00000619572(transcript)|interpro:IPR025261|interpro:IPR033473|mint:Q32MH5 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377 rogid:MaU58q95wEB3FxQaY/ri5QKm06M9606 rigid:j8RZ/Qe63FdMRsQHN5NS8pHAkho false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D09 uniprotkb:O60739 intact:EBI-21285965|ensemblbacteria:AAO90464 intact:EBI-1043343|uniprotkb:Q9UQF8|ensembl:ENSP00000232905 psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name) psi-mi:eif1b_human(display_long)|uniprotkb:Protein translation factor SUI1 homolog GC20(gene name synonym)|uniprotkb:EIF1B(gene name)|psi-mi:EIF1B(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286013|imex:IM-26899-143 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90464(transcript)|ensemblbacteria:CBU_0937(gene)|refseq:NP_819950.2|mint:Q83D09 ensembl:ENSG00000114784(gene)|ensembl:ENST00000232905(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0043024"(ribosomal small subunit binding)|interpro:IPR001950(Translation initiation factor SUI1)|interpro:IPR005874(Eukaryotic translation initiation factor SUI1)|interpro:IPR036877|mint:O60739|refseq:NP_005866.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377 rogid:0nnqCaTD/q0KhGcITR0LD7WLET09606 rigid:rw5O6tnIyE4XcCDKbDSJ/delB9w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D09 uniprotkb:Q9UJC3 intact:EBI-21285965|ensemblbacteria:AAO90464 intact:EBI-746704|uniprotkb:O60561|uniprotkb:Q5TG44|uniprotkb:A8MU44|uniprotkb:B4DX15|uniprotkb:A8K8E9|intact:EBI-10969618|ensembl:ENSP00000360252 psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name) psi-mi:hook1_human(display_long)|uniprotkb:HOOK1(gene name)|psi-mi:HOOK1(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286049|imex:IM-26899-467 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90464(transcript)|ensemblbacteria:CBU_0937(gene)|refseq:NP_819950.2|mint:Q83D09 refseq:NP_056972.1|ensembl:ENSG00000134709(gene)|ensembl:ENST00000371208(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007030"(Golgi organization)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0070695"(FHF complex)|go:"GO:1905198"(manchette assembly)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR008636(HOOK)|interpro:IPR036872|interpro:IPR043936|mint:Q9UJC3 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377 rogid:QOcYbuKfnNIlNKzos5v+0+A2h3I9606 rigid:jtGwjOUXN4uyItWKVbk7gbPMBGw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D09 uniprotkb:Q96BW5 intact:EBI-21285965|ensemblbacteria:AAO90464 intact:EBI-4291023|uniprotkb:B0YJ77|uniprotkb:B3KTF5|uniprotkb:D3DRU0|uniprotkb:Q9BY46|ensembl:ENSP00000367239|ensembl:ENSP00000439485 psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name) psi-mi:pter_human(display_long)|uniprotkb:PTER(gene name)|psi-mi:PTER(display_short)|uniprotkb:Parathion hydrolase-related protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286109|imex:IM-26899-251 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90464(transcript)|ensemblbacteria:CBU_0937(gene)|refseq:NP_819950.2|mint:Q83D09 refseq:NP_001001484.1|refseq:NP_109589.2|refseq:NP_001248765.1|refseq:NP_001248766.1|refseq:NP_001248767.1|refseq:XP_016872418.1|refseq:XP_016872419.1|ensembl:ENSG00000165983(gene)|ensembl:ENST00000378000(transcript)|ensembl:ENST00000535784(transcript)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009056"(catabolic process)|go:"GO:0016788"(hydrolase activity, acting on ester bonds)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001559(Aryldialkylphosphatase)|interpro:IPR017947|interpro:IPR032466|mint:Q96BW5 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377 rogid:znA1p3a8Ksrqx2dDHiAegKP5JaY9606 rigid:gOsU8/1C29ji/3MUj8uT7T9CdF4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D09 uniprotkb:O15355 intact:EBI-21285965|ensemblbacteria:AAO90464 intact:EBI-725702|ensembl:ENSP00000342778 psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name) psi-mi:ppm1g_human(display_long)|uniprotkb:Protein phosphatase 2C isoform gamma(gene name synonym)|uniprotkb:Protein phosphatase magnesium-dependent 1 gamma(gene name synonym)|uniprotkb:Protein phosphatase 1C(gene name synonym)|uniprotkb:PPM1G(gene name)|psi-mi:PPM1G(display_short)|uniprotkb:PPM1C(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286103|imex:IM-26899-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90464(transcript)|ensemblbacteria:CBU_0937(gene)|refseq:NP_819950.2|mint:Q83D09 refseq:NP_817092.1|ensembl:ENST00000344034(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|ensembl:ENSG00000115241(gene)|go:"GO:0016020"(membrane)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C, manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:O15355|dip:DIP-29404N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377 rogid:j9ut2f7QHVyOtsLuYJ8e2XOP3HE9606 rigid:uMqRvA+74R5rYxYbcTqwVG8fhRs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y2A7 uniprotkb:Q83D09 intact:EBI-389845|uniprotkb:O60329|uniprotkb:Q53QN5|uniprotkb:Q53S94|uniprotkb:Q53Y35|ensembl:ENSP00000355348 intact:EBI-21285965|ensemblbacteria:AAO90464 psi-mi:nckp1_human(display_long)|uniprotkb:NCKAP1(gene name)|psi-mi:NCKAP1(display_short)|uniprotkb:HEM2(gene name synonym)|uniprotkb:KIAA0587(gene name synonym)|uniprotkb:NAP1(gene name synonym)|uniprotkb:p125Nap1(gene name synonym)|uniprotkb:Membrane-associated protein HEM-2(gene name synonym) psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286079|imex:IM-26899-369 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_038464.1|refseq:NP_995314.1|ensembl:ENSG00000061676(gene)|ensembl:ENST00000361354(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006915"(apoptotic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031209"(SCAR complex)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031941"(filamentous actin)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR019137|mint:Q9Y2A7|rcsb pdb:3P8C|rcsb pdb:4N78|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9664422|dip:DIP-31119N ensemblbacteria:AAO90464(transcript)|ensemblbacteria:CBU_0937(gene)|refseq:NP_819950.2|mint:Q83D09 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:xj4ySr6cf374UbE/gfuxMx1X0tw9606 rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377 rigid:+itzX9GOtgkliwdRuwiK3zebxjM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D09 uniprotkb:P51003 intact:EBI-21285965|ensemblbacteria:AAO90464 intact:EBI-359376|uniprotkb:Q86SX4|uniprotkb:Q86TV0|uniprotkb:Q8IYF5|uniprotkb:Q9BVU2|ensembl:ENSP00000216277 psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name) psi-mi:papoa_human(display_long)|uniprotkb:PAPOLA(gene name)|psi-mi:PAPOLA(display_short)|uniprotkb:PAP(gene name synonym)|uniprotkb:Polynucleotide adenylyltransferase alpha(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286091|imex:IM-26899-573 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90464(transcript)|ensemblbacteria:CBU_0937(gene)|refseq:NP_819950.2|mint:Q83D09 refseq:NP_116021.2|refseq:NP_001238935.1|refseq:NP_001238936.1|ensembl:ENSG00000090060(gene)|ensembl:ENST00000216277(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031440"(regulation of mRNA 3'-end processing)|go:"GO:0043631"(RNA polyadenylation)|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR007010("Poly(A) polymerase, RNA-binding region")|interpro:IPR007012("Poly(A) polymerase, central region")|interpro:IPR011068(Nucleotidyltransferase, class I, C-terminal-like)|interpro:IPR014492("Poly(A) polymerase")|interpro:IPR043519|mint:P51003|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|refseq:NP_001280556.1|refseq:NP_001280557.1|refseq:NP_001280561.1|dip:DIP-27610N|dip:DIP-40865N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377 rogid:rRMBZRE1yFjnO+pnz5g4k+u7hwo9606 rigid:fxlKj41Xm/K92AlaxH3uYNP0N3s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UQ80 uniprotkb:Q83D09 intact:EBI-924893|uniprotkb:Q9UM59|uniprotkb:O43846|ensembl:ENSP00000302886 intact:EBI-21285965|ensemblbacteria:AAO90464 psi-mi:pa2g4_human(display_long)|uniprotkb:PA2G4(gene name)|psi-mi:PA2G4(display_short)|uniprotkb:Cell cycle protein p38-2G4 homolog(gene name synonym)|uniprotkb:ErbB3-binding protein 1(gene name synonym)|uniprotkb:EBP1(gene name synonym) psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286085|imex:IM-26899-249 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006182.2|dip:DIP-31275N|ensembl:ENSG00000170515(gene)|ensembl:ENST00000303305(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR004545(Proliferation-associated protein 1)|interpro:IPR036005|interpro:IPR036388|interpro:IPR036390|mint:Q9UQ80|rcsb pdb:2Q8K|rcsb pdb:3J2I|rcsb pdb:6CHT|rcsb pdb:6LSR|rcsb pdb:6SXO|rcsb pdb:6WM8|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-6798695|interpro:IPR018349 ensemblbacteria:AAO90464(transcript)|ensemblbacteria:CBU_0937(gene)|refseq:NP_819950.2|mint:Q83D09 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:OGRaz1uHilOnGXaAr/yeKMlCyns9606 rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377 rigid:2Cx9ji5CNRGHf9ct5P+Emiy5pIs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D09 uniprotkb:Q5T2W1 intact:EBI-21285965|ensemblbacteria:AAO90464 intact:EBI-349819|uniprotkb:O60450|uniprotkb:Q5T5P6|uniprotkb:Q9BQ41|ensembl:ENSP00000342143|ensembl:ENSP00000394485|uniprotkb:B4DPB9|uniprotkb:E7EU02 psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name) psi-mi:nhrf3_human(display_long)|uniprotkb:PDZK1(gene name)|psi-mi:PDZK1(display_short)|uniprotkb:CFTR-associated protein of 70 kDa(gene name synonym)|uniprotkb:Na/Pi cotransporter C-terminal-associated protein 1(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 3(gene name synonym)|uniprotkb:"Na(+)/H(+) exchanger regulatory factor 3"(gene name synonym)|uniprotkb:CAP70(gene name synonym)|uniprotkb:NHERF3(gene name synonym)|uniprotkb:PDZD1(gene name synonym)|uniprotkb:PDZ domain-containing protein 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286097|imex:IM-26899-147 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90464(transcript)|ensemblbacteria:CBU_0937(gene)|refseq:NP_819950.2|mint:Q83D09 refseq:NP_001188254.1|refseq:NP_002605.2|ensembl:ENSG00000174827(gene)|rcsb pdb:3TMH|rcsb pdb:4Q2P|rcsb pdb:6EZI|ensembl:ENST00000344770(transcript)|ensembl:ENST00000417171(transcript)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0015879"(carnitine transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031526"(brush border membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0032414"(positive regulation of ion transmembrane transporter activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0044070"(regulation of anion transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1904064"(positive regulation of cation transmembrane transport)|go:"GO:1905477"(positive regulation of protein localization to membrane)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR041489|mint:Q5T2W1|rcsb pdb:2EEI|rcsb pdb:2EEJ|rcsb pdb:2VSP|refseq:NP_001188255.1|refseq:XP_016856953.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377 rogid:sU0SZ8m9Or0LFmLo9dh6B7RBJWs9606 rigid:agw6Gkzglq28fUXdlC2V6Wi+nw4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D09 uniprotkb:P41220 intact:EBI-21285965|ensemblbacteria:AAO90464 intact:EBI-712388|ensembl:ENSP00000235382|intact:EBI-1050416|uniprotkb:Q6I9U5 psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name) psi-mi:rgs2_human(display_long)|uniprotkb:G0/G1 switch regulatory protein 8(gene name synonym)|uniprotkb:RGS2(gene name)|psi-mi:RGS2(display_short)|uniprotkb:G0S8(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 31 protein(gene name synonym)|uniprotkb:GIG31(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286115|imex:IM-26899-575 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90464(transcript)|ensemblbacteria:CBU_0937(gene)|refseq:NP_819950.2|mint:Q83D09 refseq:NP_002914.1|ensembl:ENSG00000116741(gene)|ensembl:ENST00000235382(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010519"(negative regulation of phospholipase activity)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030728"(ovulation)|go:"GO:0043005"(neuron projection)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060087"(relaxation of vascular associated smooth muscle)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0140194"(negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process)|go:"GO:1900924"(negative regulation of glycine import across plasma membrane)|interpro:IPR016137(Regulator of G protein signalling superfamily)|go:"GO:0045471"(response to ethanol)|interpro:IPR024066|interpro:IPR034947|interpro:IPR036305|mint:P41220|rcsb pdb:2AF0|rcsb pdb:2V4Z|rcsb pdb:4EKC|rcsb pdb:4EKD|reactome:R-HSA-416476|dip:DIP-44289N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377 rogid:7tdfhNRRyaPKS2taH6iurdHCZ+s9606 rigid:gfWKBbLVsbohGyzKngG4Sx69nxM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D09 uniprotkb:Q9NQG5 intact:EBI-21285965|ensemblbacteria:AAO90464 intact:EBI-747925|uniprotkb:Q1WDE7|uniprotkb:Q6PKF4|ensembl:ENSP00000362532 psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name) psi-mi:rpr1b_human(display_long)|uniprotkb:RPRD1B(gene name)|psi-mi:RPRD1B(display_short)|uniprotkb:C20orf77(gene name synonym)|uniprotkb:CREPT(gene name synonym)|uniprotkb:Cell cycle-related and expression-elevated protein in tumor(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286121|imex:IM-26899-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90464(transcript)|ensemblbacteria:CBU_0937(gene)|refseq:NP_819950.2|mint:Q83D09 refseq:NP_067038.1|ensembl:ENSG00000101413(gene)|ensembl:ENST00000373433(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q9NQG5|rcsb pdb:4FLA|rcsb pdb:4FU3|rcsb pdb:4HFG|rcsb pdb:4NAD|rcsb pdb:4Q94|rcsb pdb:4Q96|reactome:R-HSA-6807505|dip:DIP-61537N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377 rogid:1P0sOiLV5eQXrRj+vENpc6L/z/Q9606 rigid:F8egyHraxMj4DDcQZxH1SlA8VIo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D09 uniprotkb:Q9NY72 intact:EBI-21285965|ensemblbacteria:AAO90464 intact:EBI-17247926|uniprotkb:A5H1I5|uniprotkb:Q17RL3|uniprotkb:Q9ULR2|ensembl:ENSP00000299333|ensembl:ENSP00000376523|ensembl:ENSP00000432785|ensembl:ENSP00000499439|ensembl:ENSP00000499755 psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name) psi-mi:scn3b_human(display_long)|uniprotkb:SCN3B(gene name)|psi-mi:SCN3B(display_short)|uniprotkb:KIAA1158(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286133|imex:IM-26899-149 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90464(transcript)|ensemblbacteria:CBU_0937(gene)|refseq:NP_819950.2|mint:Q83D09 refseq:NP_001035241.1|refseq:NP_060870.1|refseq:XP_011541199.1|ensembl:ENSG00000166257(gene)|ensembl:ENST00000299333(transcript)|ensembl:ENST00000392770(transcript)|ensembl:ENST00000530277(transcript)|ensembl:ENST00000657123(transcript)|ensembl:ENST00000657191(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007399"(nervous system development)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0030018"(Z disc)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051899"(membrane depolarization)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086006"(voltage-gated sodium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086015"(SA node cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR027096|interpro:IPR027098|interpro:IPR036179|mint:Q9NY72|rcsb pdb:4L1D|reactome:R-HSA-445095|reactome:R-HSA-5576892 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377 rogid:JibaGARh6xabzhHZEf16XAaUgOg9606 rigid:JZ8mJzl+F7ziEoyorwBxIaYOrgw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96CM3 uniprotkb:Q83D09 intact:EBI-7825200|intact:EBI-11113381|ensembl:ENSP00000298317|uniprotkb:E9PML2|uniprotkb:Q96K56|intact:MINT-8052462 intact:EBI-21285965|ensemblbacteria:AAO90464 psi-mi:rusd4_human(display_long)|uniprotkb:RPUSD4(gene name)|psi-mi:RPUSD4(display_short)|uniprotkb:RNA pseudouridylate synthase domain-containing protein 4(gene name synonym) psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286127|imex:IM-26899-471 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0070902"(mitochondrial tRNA pseudouridine synthesis)|go:"GO:1990400"(mitochondrial ribosomal large subunit rRNA binding)|interpro:IPR006145(Pseudouridine synthase)|interpro:IPR006224(Pseudouridine synthase, conserved site)|interpro:IPR020103|mint:Q96CM3|rcsb pdb:5UBA|ensembl:ENSG00000165526(gene)|ensembl:ENST00000298317(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000455"(enzyme-directed rRNA pseudouridine synthesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009982"(pseudouridine synthase activity)|refseq:NP_116184.2|refseq:NP_001138299.1 ensemblbacteria:AAO90464(transcript)|ensemblbacteria:CBU_0937(gene)|refseq:NP_819950.2|mint:Q83D09 - comment:mint - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:UxJTvd9B7xEGEh9W7niR/AAOdLM9606 rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377 rigid:pU3QXjSrceLg7jJRWnYFhw/jhvY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:B5QSC8 uniprotkb:Q9H8H3 intact:EBI-21286181|ensemblbacteria:ACI15292 intact:EBI-1390168|uniprotkb:Q9H7R3|uniprotkb:Q9UHZ7|uniprotkb:Q9Y422|ensembl:ENSP00000331787|ensembl:ENSP00000447542|ensembl:ENSP00000448785 psi-mi:b5qsc8_coxbu(display_long)|uniprotkb:CBU_1379a(orf name) psi-mi:met7a_human(display_long)|uniprotkb:Protein AAM-B(gene name synonym)|uniprotkb:METTL7A(gene name)|psi-mi:METTL7A(display_short)|uniprotkb:PRO0066(orf name)|uniprotkb:UNQ1902/PRO4348(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286221|imex:IM-26899-577 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:ACI15292(transcript)|ensemblbacteria:CBU_1379a(gene)|go:"GO:0009279"(cell outer membrane)|go:"GO:0015288"(porin activity)|go:"GO:0046930"(pore complex)|refseq:WP_010958188.1|refseq:YP_002333001.1|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR000498(Outer membrane protein, OmpA-like, transmembrane region)|mint:B5QSC8 refseq:NP_054752.3|refseq:XP_006719395.1|ensembl:ENSG00000185432(gene)|ensembl:ENST00000332160(transcript)|ensembl:ENST00000547104(transcript)|ensembl:ENST00000548553(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0016020"(membrane)|go:"GO:0032259"(methylation)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR029063|mint:Q9H8H3|reactome:R-HSA-6798695 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:XY+ktagDlhTCiKO++WWFBUqpS4U227377 rogid:b8PnE+BClVn1MzOlg0uIaqDSOaU9606 rigid:/QPQcpHWaAagTAXKs7z8nSAOtfo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:B5QSC8 uniprotkb:Q9Y5V3 intact:EBI-21286181|ensemblbacteria:ACI15292 intact:EBI-716006|uniprotkb:Q5VSH6|uniprotkb:Q8IZ84|uniprotkb:Q8WY92|uniprotkb:Q9H352|uniprotkb:Q9HBT4|uniprotkb:Q9UF36|ensembl:ENSP00000325333|ensembl:ENSP00000364874|ensembl:ENSP00000364927 psi-mi:b5qsc8_coxbu(display_long)|uniprotkb:CBU_1379a(orf name) psi-mi:magd1_human(display_long)|uniprotkb:MAGE-D1 antigen(gene name synonym)|uniprotkb:Neurotrophin receptor-interacting MAGE homolog(gene name synonym)|uniprotkb:MAGE tumor antigen CCF(gene name synonym)|uniprotkb:MAGED1(gene name)|psi-mi:MAGED1(display_short)|uniprotkb:NRAGE(gene name synonym)|uniprotkb:PRO2292(orf name)|uniprotkb:PP2250(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286215|imex:IM-26899-375 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:ACI15292(transcript)|ensemblbacteria:CBU_1379a(gene)|go:"GO:0009279"(cell outer membrane)|go:"GO:0015288"(porin activity)|go:"GO:0046930"(pore complex)|refseq:WP_010958188.1|refseq:YP_002333001.1|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR000498(Outer membrane protein, OmpA-like, transmembrane region)|mint:B5QSC8 refseq:NP_001005332.1|refseq:NP_001005333.1|refseq:NP_008917.3|ensembl:ENSP00000325333|ensembl:ENST00000375695|ensembl:ENSP00000364847|ensembl:ENSP00000364874|ensembl:ENSP00000364927|refseq:XP_011529137.1|refseq:XP_016885467.1|refseq:XP_016885468.1|refseq:XP_016885469.1|ensembl:ENSG00000179222(gene)|ensembl:ENST00000326587(transcript)|ensembl:ENST00000375722(transcript)|ensembl:ENST00000375772(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR030083|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:Q9Y5V3|reactome:R-HSA-193648|reactome:R-HSA-418889 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:XY+ktagDlhTCiKO++WWFBUqpS4U227377 rogid:UTg0r4zGMXfTZqBN4SFmgu6IukI9606 rigid:2CuChbD/6TdyUhcQfRlSUmM1yEQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:B5QSC8 uniprotkb:P35555 intact:EBI-21286181|ensemblbacteria:ACI15292 intact:EBI-2505934|ensembl:ENSP00000325527|uniprotkb:B2RUU0|uniprotkb:Q15972|uniprotkb:Q75N87|uniprotkb:D2JYH6 psi-mi:b5qsc8_coxbu(display_long)|uniprotkb:CBU_1379a(orf name) psi-mi:fbn1_human(display_long)|uniprotkb:FBN1(gene name)|psi-mi:FBN1(display_short)|uniprotkb:FBN(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286209|imex:IM-26899-681 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:ACI15292(transcript)|ensemblbacteria:CBU_1379a(gene)|go:"GO:0009279"(cell outer membrane)|go:"GO:0015288"(porin activity)|go:"GO:0046930"(pore complex)|refseq:WP_010958188.1|refseq:YP_002333001.1|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR000498(Outer membrane protein, OmpA-like, transmembrane region)|mint:B5QSC8 ensembl:ENSG00000166147(gene)|ensembl:ENST00000316623(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001527"(microfibril)|go:"GO:0001656"(metanephros development)|go:"GO:0005178"(integrin binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0007507"(heart development)|go:"GO:0008201"(heparin binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030023"(extracellular matrix constituent conferring elasticity)|go:"GO:0031012"(extracellular matrix)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034199"(activation of protein kinase A activity)|go:"GO:0035582"(sequestering of BMP in extracellular matrix)|go:"GO:0035583"(sequestering of TGFbeta in extracellular matrix)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0048048"(embryonic eye morphogenesis)|go:"GO:0048050"(post-embryonic eye morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:2001205"(negative regulation of osteoclast development)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011398(Fibrillin)|interpro:IPR017878|interpro:IPR018097|interpro:IPR026823|interpro:IPR036773|interpro:IPR040872|mint:P35555|rcsb pdb:1APJ|rcsb pdb:1EMN|rcsb pdb:1EMO|rcsb pdb:1LMJ|rcsb pdb:1UZJ|rcsb pdb:1UZK|rcsb pdb:1UZP|rcsb pdb:1UZQ|rcsb pdb:2M74|rcsb pdb:2W86|rcsb pdb:5MS9|reactome:R-HSA-1474228|reactome:R-HSA-1566948|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:NP_000129.3|dip:DIP-29985N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:XY+ktagDlhTCiKO++WWFBUqpS4U227377 rogid:YEO0ZRTezrjEAyTaos1pm2hUDXg9606 rigid:7zJeBA7nOENsbxn4DvQGXfyBWBg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:B5QSC8 uniprotkb:Q9UBS4 intact:EBI-21286181|ensemblbacteria:ACI15292 intact:EBI-713113|ensembl:ENSP00000265028|ensembl:ENSP00000414398|uniprotkb:Q542Y5|uniprotkb:Q542Y9|uniprotkb:Q6IAQ8|uniprotkb:Q96JC6 psi-mi:b5qsc8_coxbu(display_long)|uniprotkb:CBU_1379a(orf name) psi-mi:djb11_human(display_long)|uniprotkb:HDJ9(gene name synonym)|uniprotkb:DnaJ protein homolog 9(gene name synonym)|uniprotkb:ER-associated Hsp40 co-chaperone(gene name synonym)|uniprotkb:ER-associated DNAJ(gene name synonym)|uniprotkb:HEDJ(gene name synonym)|uniprotkb:Human DnaJ protein 9(gene name synonym)|uniprotkb:PWP1-interacting protein 4(gene name synonym)|uniprotkb:APOBEC1-binding protein 2(gene name synonym)|uniprotkb:PSEC0121(orf name)|uniprotkb:DNAJB11(gene name)|psi-mi:DNAJB11(display_short)|uniprotkb:EDJ(gene name synonym)|uniprotkb:ERJ3(gene name synonym)|uniprotkb:UNQ537/PRO1080(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 3(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286203|imex:IM-26899-373 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:ACI15292(transcript)|ensemblbacteria:CBU_1379a(gene)|go:"GO:0009279"(cell outer membrane)|go:"GO:0015288"(porin activity)|go:"GO:0046930"(pore complex)|refseq:WP_010958188.1|refseq:YP_002333001.1|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR000498(Outer membrane protein, OmpA-like, transmembrane region)|mint:B5QSC8 ensembl:ENSG00000090520(gene)|ensembl:ENST00000265028(transcript)|ensembl:ENST00000439351(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0101031"(chaperone complex)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:Q9UBS4|reactome:R-HSA-381038|go:"GO:0006457"(protein folding)|refseq:NP_057390.1|dip:DIP-29678N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:XY+ktagDlhTCiKO++WWFBUqpS4U227377 rogid:B8jV6uvPmoGzOEpe4qrMiYloSok9606 rigid:6CQRbD8fYUXhsGSNTTzGPcOJgEs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:B5QSC8 uniprotkb:O75534 intact:EBI-21286181|ensemblbacteria:ACI15292 intact:EBI-719186|uniprotkb:O94961|uniprotkb:Q5TF04|uniprotkb:Q5TF05|uniprotkb:Q68DI9|uniprotkb:Q9Y2S4|uniprotkb:E9PGZ0|uniprotkb:Q68DF1|intact:EBI-1059183|ensembl:ENSP00000351329|ensembl:ENSP00000432958|uniprotkb:A8K281|uniprotkb:G5E9Q2 psi-mi:b5qsc8_coxbu(display_long)|uniprotkb:CBU_1379a(orf name) psi-mi:csde1_human(display_long)|uniprotkb:Protein UNR(gene name synonym)|uniprotkb:N-ras upstream gene protein(gene name synonym)|uniprotkb:CSDE1(gene name)|psi-mi:CSDE1(display_short)|uniprotkb:D1S155E(gene name synonym)|uniprotkb:KIAA0885(gene name synonym)|uniprotkb:NRU(gene name synonym)|uniprotkb:UNR(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286197|imex:IM-26899-153 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:ACI15292(transcript)|ensemblbacteria:CBU_1379a(gene)|go:"GO:0009279"(cell outer membrane)|go:"GO:0015288"(porin activity)|go:"GO:0046930"(pore complex)|refseq:WP_010958188.1|refseq:YP_002333001.1|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR000498(Outer membrane protein, OmpA-like, transmembrane region)|mint:B5QSC8 refseq:NP_001007554.1|refseq:NP_001123995.1|refseq:NP_001229820.1|refseq:NP_001229821.1|refseq:NP_001229822.1|refseq:NP_009089.4|ensembl:ENSG00000009307(gene)|ensembl:ENST00000358528(transcript)|ensembl:ENST00000534699(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008584"(male gonad development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0034063"(stress granule assembly)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0070966"(nuclear-transcribed mRNA catabolic process, no-go decay)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR019844|interpro:IPR024642|mint:O75534|rcsb pdb:1WFQ|rcsb pdb:1X65|rcsb pdb:2YTV|rcsb pdb:2YTX|rcsb pdb:2YTY|interpro:IPR012340(Nucleic acid-binding, OB-fold) - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:XY+ktagDlhTCiKO++WWFBUqpS4U227377 rogid:fpL1bONjNXyXjIO/akUIIoeEGTc9606 rigid:job8K3BVcpZQlM7F+wlDdGUZr0U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D09 uniprotkb:P22307 intact:EBI-21285965|ensemblbacteria:AAO90464 intact:EBI-1050999|uniprotkb:Q15432|uniprotkb:Q16622|uniprotkb:Q99430|uniprotkb:Q5VVZ1|uniprotkb:D3DQ37|ensembl:ENSP00000360569|uniprotkb:Q6NXF4|uniprotkb:B4DHP6|uniprotkb:A6NM69|uniprotkb:B4DGJ9|uniprotkb:C9JC79|uniprotkb:E1B6W5|uniprotkb:F2Z3J1 psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name) psi-mi:scp2_human(display_long)|uniprotkb:Propanoyl-CoA C-acyltransferase(gene name synonym)|uniprotkb:Sterol carrier protein X(gene name synonym)|uniprotkb:SCP-chi(gene name synonym)|uniprotkb:SCPX(gene name synonym)|uniprotkb:SCP2(gene name)|psi-mi:SCP2(display_short)|uniprotkb:Acetyl-CoA C-myristoyltransferase(gene name synonym)|uniprotkb:Non-specific lipid-transfer protein(gene name synonym)|uniprotkb:SCP-2/3-oxoacyl-CoA thiolase(gene name synonym)|uniprotkb:SCP-2/thiolase(gene name synonym)|uniprotkb:Straight-chain acyl-CoA oxidase(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286139|imex:IM-26899-679 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90464(transcript)|ensemblbacteria:CBU_0937(gene)|refseq:NP_819950.2|mint:Q83D09 refseq:NP_001180528.1|refseq:NP_001007100.1|refseq:NP_001007101.1|refseq:NP_001007251.1|refseq:NP_002970.2|ensembl:ENSG00000116171(gene)|ensembl:ENST00000371514(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0006701"(progesterone biosynthetic process)|go:"GO:0007031"(peroxisome organization)|go:"GO:0008206"(bile acid metabolic process)|go:"GO:0008526"(phosphatidylinositol transfer activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015914"(phospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0032367"(intracellular cholesterol transport)|go:"GO:0032385"(positive regulation of intracellular cholesterol transport)|go:"GO:0032934"(sterol binding)|go:"GO:0032959"(inositol trisphosphate biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033540"(fatty acid beta-oxidation using acyl-CoA oxidase)|go:"GO:0033814"(propanoyl-CoA C-acyltransferase activity)|go:"GO:0036042"(long-chain fatty acyl-CoA binding)|go:"GO:0036109"(alpha-linolenic acid metabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045940"(positive regulation of steroid metabolic process)|go:"GO:0050632"(propionyl-CoA C2-trimethyltridecanoyltransferase activity)|go:"GO:0050633"(acetyl-CoA C-myristoyltransferase activity)|go:"GO:0070538"(oleic acid binding)|go:"GO:0071071"(regulation of phospholipid biosynthetic process)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0120019"(phosphatidylcholine transfer activity)|go:"GO:0120020"(cholesterol transfer activity)|go:"GO:1901373"(lipid hydroperoxide transport)|interpro:IPR003033(Sterol-binding)|interpro:IPR016039(Thiolase-like)|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|interpro:IPR036527|mint:P22307|rcsb pdb:1QND|reactome:R-HSA-193368|reactome:R-HSA-2046106|reactome:R-HSA-389887|reactome:R-HSA-9033241|reactome:R-HSA-9033500|rcsb pdb:2C0L|refseq:XP_016857535.1|refseq:NP_001007099.1|refseq:NP_001180546.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377 rogid:Vwnu7RuD/2qhcH55Fl9v2TMErtc9606 rigid:vCBOa7rzNaWM+UTAwS/5Y7E5yBg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O95171 uniprotkb:Q83C21 intact:EBI-7543896|uniprotkb:B7Z797|intact:MINT-8162407|intact:UNK-5430852|uniprotkb:Q86X00|intact:UNK-5458327|uniprotkb:Q53H61|uniprotkb:F5H651|uniprotkb:Q5W0S8|uniprotkb:Q5W0S9|intact:MINT-3975264|ensembl:ENSP00000302579 intact:EBI-21286157|ensemblbacteria:AAO90819 psi-mi:scel_human(display_long)|uniprotkb:SCEL(gene name)|psi-mi:SCEL(display_short) psi-mi:q83c21_coxbu(display_long)|uniprotkb:CBU_1314(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286175|imex:IM-26899-477 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_659001.2|refseq:NP_001154178.1|refseq:NP_003834.3|ensembl:ENSG00000136155(gene)|ensembl:ENST00000349847(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0008544"(epidermis development)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR001781(Zinc finger, LIM-type)|mint:O95171 ensemblbacteria:AAO90819(transcript)|ensemblbacteria:CBU_1314(gene)|refseq:NP_820305.2|refseq:WP_010958144.1|mint:Q83C21 - comment:mint|function:May function in the assembly or regulation of proteins in the cornified envelope. The LIM domain may be involved in homotypic or heterotypic associations and may function to localize sciellin to the cornified envelope - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:1sNj7h14CEpm44d5qulY/tWlYgE9606 rogid:DIFe5BH2MWRB3uuIhKXumw9z8+w227377 rigid:ndPUKDlOUA61iEIMN6+XnDGzYyI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83C21 uniprotkb:P62191 intact:EBI-21286157|ensemblbacteria:AAO90819 intact:EBI-357598|uniprotkb:P49014|uniprotkb:Q03527|uniprotkb:Q6IAW0|uniprotkb:Q96AZ3|ensembl:ENSP00000261303|uniprotkb:Q6NW36|uniprotkb:B4DR63 psi-mi:q83c21_coxbu(display_long)|uniprotkb:CBU_1314(locus name) psi-mi:prs4_human(display_long)|uniprotkb:PSMC1(gene name)|psi-mi:PSMC1(display_short)|uniprotkb:26S proteasome AAA-ATPase subunit RPT2(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286169|imex:IM-26899-37 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90819(transcript)|ensemblbacteria:CBU_1314(gene)|refseq:NP_820305.2|refseq:WP_010958144.1|mint:Q83C21 refseq:NP_002793.2|ensembl:ENST00000261303(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|ensembl:ENSG00000100764(gene)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035244|interpro:IPR041569|mint:P62191|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFQ|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-8852276|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|refseq:NP_001317141.1|refseq:XP_016876959.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:DIFe5BH2MWRB3uuIhKXumw9z8+w227377 rogid:oGEtU7Cv0qversbD3WQgAo5H9pM9606 rigid:aUpbIu5iSAzRA0heiLW6jgEWi3Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83C21 uniprotkb:P25788 intact:EBI-21286157|ensemblbacteria:AAO90819 intact:EBI-348380|ensembl:ENSP00000216455|uniprotkb:Q86U83|uniprotkb:Q8N1D8|uniprotkb:Q9BS70|uniprotkb:B2RCK6 psi-mi:q83c21_coxbu(display_long)|uniprotkb:CBU_1314(locus name) psi-mi:psa3_human(display_long)|uniprotkb:PSMA3(gene name)|psi-mi:PSMA3(display_short)|uniprotkb:PSC8(gene name synonym)|uniprotkb:Proteasome component C8(gene name synonym)|uniprotkb:Macropain subunit C8(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C8(gene name synonym)|uniprotkb:HC8(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286163|imex:IM-26899-151 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90819(transcript)|ensemblbacteria:CBU_1314(gene)|refseq:NP_820305.2|refseq:WP_010958144.1|mint:Q83C21 refseq:NP_002779.1|refseq:NP_687033.1|ensembl:ENSG00000100567(gene)|ensembl:ENST00000216455(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0045202"(synapse)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR037555|mint:P25788|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|rcsb pdb:5DSV|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|rcsb pdb:7E55|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|rcsb pdb:5T0H|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-174084|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-174113|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-9010553|dip:DIP-29366N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:DIFe5BH2MWRB3uuIhKXumw9z8+w227377 rogid:9Er/PY50/GVoCr5yAPXlkfxtP0k9606 rigid:Fe0xPj6fhFmTl++WO3hixYlIiyQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D09 uniprotkb:Q9P2E3 intact:EBI-21285965|ensemblbacteria:AAO90464 intact:EBI-308745|uniprotkb:Q9BQM7|uniprotkb:Q9BQM8|uniprotkb:Q9H8C1|uniprotkb:Q9H9S2|uniprotkb:Q9NUM1|uniprotkb:Q9NWW1|ensembl:ENSP00000360817|ensembl:ENSP00000379412 psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name) psi-mi:znfx1_human(display_long)|uniprotkb:ZNFX1(gene name)|psi-mi:ZNFX1(display_short)|uniprotkb:KIAA1404(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286151|imex:IM-26899-475 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90464(transcript)|ensemblbacteria:CBU_0937(gene)|refseq:NP_819950.2|mint:Q83D09 refseq:NP_066363.1|ensembl:ENSG00000124201(gene)|ensembl:ENST00000371752(transcript)|ensembl:ENST00000396105(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0031380"(nuclear RNA-directed RNA polymerase complex)|interpro:IPR000967(Zinc finger, NF-X1-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|mint:Q9P2E3|refseq:XP_006723899.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377 rogid:2vNUbYE3//YGh0eabKbzldLESF49606 rigid:QdwKX7hrIYYXf3tqMwFUAQIe6Kg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D09 uniprotkb:Q8N4F4 intact:EBI-21285965|ensemblbacteria:AAO90464 intact:EBI-740525|ensembl:ENSP00000480336|uniprotkb:A0A087WWM3|uniprotkb:C9JC66 psi-mi:y937_coxbu(display_long)|uniprotkb:CBU_0937(locus name) psi-mi:s22ao_human(display_long)|uniprotkb:SLC22A24(gene name)|psi-mi:SLC22A24(display_short)|uniprotkb:Solute carrier family 22 member 24(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286145|imex:IM-26899-473 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90464(transcript)|ensemblbacteria:CBU_0937(gene)|refseq:NP_819950.2|mint:Q83D09 ensembl:ENSG00000197658(gene)|ensembl:ENST00000612278(transcript)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0015711"(organic anion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0035382"(sterol transmembrane transport)|interpro:IPR005828(General substrate transporter)|interpro:IPR020846|interpro:IPR036259|mint:Q8N4F4|refseq:NP_775857.2|refseq:NP_001129978.2 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2020/03/02 rogid:x/PAFGiFZ0BzOf9MprZtAfwIp+E227377 rogid:p413cx5Lhyt5J082RAt1u82SJ609606 rigid:Ml7w3DS8XSGAbQ6+QoaeVF/9/Ec false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:B5QSC8 uniprotkb:Q9UIF8 intact:EBI-21286181|ensemblbacteria:ACI15292 intact:EBI-741542|ensembl:ENSP00000376534|uniprotkb:Q96EA1|uniprotkb:Q96SQ8|uniprotkb:Q9P252|uniprotkb:Q9Y4N8|uniprotkb:D3DPA8 psi-mi:b5qsc8_coxbu(display_long)|uniprotkb:CBU_1379a(orf name) psi-mi:baz2b_human(display_long)|uniprotkb:BAZ2B(gene name)|psi-mi:BAZ2B(display_short)|uniprotkb:KIAA1476(gene name synonym)|uniprotkb:hWALp4(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286191|imex:IM-26899-371 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:ACI15292(transcript)|ensemblbacteria:CBU_1379a(gene)|go:"GO:0009279"(cell outer membrane)|go:"GO:0015288"(porin activity)|go:"GO:0046930"(pore complex)|refseq:WP_010958188.1|refseq:YP_002333001.1|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR000498(Outer membrane protein, OmpA-like, transmembrane region)|mint:B5QSC8 ensembl:ENSG00000123636(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090647"(modulation of age-related behavioral decline)|interpro:IPR001487(Bromodomain)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR018359|interpro:IPR018501|interpro:IPR019787|interpro:IPR028941|interpro:IPR036427|interpro:IPR037374|mint:Q9UIF8|rcsb pdb:2E7O|rcsb pdb:3G0L|rcsb pdb:3Q2F|rcsb pdb:4CUP|rcsb pdb:4CUQ|ensembl:ENST00000392783(transcript)|rcsb pdb:4CUR|rcsb pdb:4CUS|rcsb pdb:4CUT|rcsb pdb:4CUU|rcsb pdb:4IR3|rcsb pdb:4IR4|rcsb pdb:4IR5|rcsb pdb:4IR6|rcsb pdb:4NR9|rcsb pdb:4NRA|rcsb pdb:4NRB|rcsb pdb:4NRC|rcsb pdb:4QC1|rcsb pdb:4QC3|rcsb pdb:4QF3|rcsb pdb:4RVR|rcsb pdb:4XUA|refseq:NP_038478.2|rcsb pdb:4XUB|rcsb pdb:5CQ3|rcsb pdb:5CQ4|rcsb pdb:5CQ5|rcsb pdb:5CQ6|rcsb pdb:5CQ7|rcsb pdb:5CQ8|rcsb pdb:5CQA|rcsb pdb:5CU8|rcsb pdb:5CUA|rcsb pdb:5CUB|rcsb pdb:5CUC|rcsb pdb:5CUD|rcsb pdb:5CUE|rcsb pdb:5CUG|rcsb pdb:5DYU|rcsb pdb:5DYX|rcsb pdb:5E73|rcsb pdb:5E74|rcsb pdb:5E9I|rcsb pdb:5E9K|rcsb pdb:5E9L|rcsb pdb:5E9M|rcsb pdb:5PCH|rcsb pdb:5PCI|rcsb pdb:5PCJ|rcsb pdb:5PCK|rcsb pdb:5PCL|rcsb pdb:5PCM|rcsb pdb:5PCN|rcsb pdb:5PCO|rcsb pdb:5PCP|rcsb pdb:5PCQ|rcsb pdb:5PCR|rcsb pdb:5PCS|rcsb pdb:5PCT|rcsb pdb:5PCG|rcsb pdb:5PCU|rcsb pdb:5PCV|rcsb pdb:5PCW|rcsb pdb:5PCX|rcsb pdb:5PCZ|rcsb pdb:5PD0|rcsb pdb:5PD1|rcsb pdb:5L8T|rcsb pdb:5L8U|rcsb pdb:5L96|rcsb pdb:5L97|rcsb pdb:5L98|rcsb pdb:5L99|rcsb pdb:5MGE|rcsb pdb:5MGF|rcsb pdb:5MGG|rcsb pdb:5OR9|rcsb pdb:5ORB|rcsb pdb:5PB7|rcsb pdb:5PB8|rcsb pdb:5PB9|rcsb pdb:5PBA|rcsb pdb:5PBB|rcsb pdb:5PBC|rcsb pdb:5PBD|rcsb pdb:5PBE|rcsb pdb:5PBF|rcsb pdb:5PBG|rcsb pdb:5PBH|rcsb pdb:5PBI|rcsb pdb:5PBJ|rcsb pdb:5PBK|rcsb pdb:5E9Y|rcsb pdb:5PBL|rcsb pdb:5PBM|rcsb pdb:5PBO|rcsb pdb:5PBP|rcsb pdb:5PBQ|rcsb pdb:5PBR|rcsb pdb:5PBS|rcsb pdb:5PBT|rcsb pdb:5PBU|rcsb pdb:5PBV|rcsb pdb:5PBW|rcsb pdb:5PBX|rcsb pdb:5PBY|rcsb pdb:5PBZ|rcsb pdb:5PC0|rcsb pdb:5PC1|rcsb pdb:5PC2|rcsb pdb:5PC3|rcsb pdb:5PC4|rcsb pdb:5PC5|rcsb pdb:5PC6|rcsb pdb:5PC7|rcsb pdb:5PC8|rcsb pdb:5PC9|rcsb pdb:5PCA|rcsb pdb:5PCB|rcsb pdb:5PCC|rcsb pdb:5PBN|rcsb pdb:5PCD|rcsb pdb:5PCE|rcsb pdb:5PCF|rcsb pdb:5PDY|rcsb pdb:5PDZ|rcsb pdb:5PE0|rcsb pdb:5PE1|rcsb pdb:5PE2|rcsb pdb:5PE3|rcsb pdb:5PE4|rcsb pdb:5PE5|rcsb pdb:5PE6|rcsb pdb:5PE7|rcsb pdb:5PE8|rcsb pdb:5PE9|rcsb pdb:5PEA|rcsb pdb:5PEB|rcsb pdb:5PEC|rcsb pdb:5PED|rcsb pdb:5PEE|rcsb pdb:5PEF|rcsb pdb:5PDX|rcsb pdb:5PEG|rcsb pdb:5PEH|rcsb pdb:5PEI|rcsb pdb:5PEJ|rcsb pdb:5PEK|rcsb pdb:5PEL|rcsb pdb:5PEM|rcsb pdb:5PEN|rcsb pdb:5PEO|rcsb pdb:5PD2|rcsb pdb:5PD4|rcsb pdb:5PD5|rcsb pdb:5PD6|rcsb pdb:5PD7|rcsb pdb:5PD8|rcsb pdb:5PD9|rcsb pdb:5PDA|rcsb pdb:5PDB|rcsb pdb:5PDC|rcsb pdb:5PDD|rcsb pdb:5PDE|rcsb pdb:5PDF|rcsb pdb:5PDG|rcsb pdb:5PDH|rcsb pdb:5PDI|rcsb pdb:5PDJ|rcsb pdb:5PD3|rcsb pdb:5PDK|rcsb pdb:5PDL|rcsb pdb:5PDM|rcsb pdb:5PDN|rcsb pdb:5PDO|rcsb pdb:5PDP|rcsb pdb:5PDQ|rcsb pdb:5PDR|rcsb pdb:5PDS|rcsb pdb:5PDT|rcsb pdb:5PDU|rcsb pdb:5PDV|rcsb pdb:5PDW|rcsb pdb:5PFN|rcsb pdb:5PFO|rcsb pdb:5PFP|rcsb pdb:5PFQ|rcsb pdb:5PFR|rcsb pdb:5PFS|rcsb pdb:5PFT|rcsb pdb:5PFU|rcsb pdb:5PFV|rcsb pdb:5PFW|rcsb pdb:5PFX|rcsb pdb:5PFY|rcsb pdb:5PFZ|rcsb pdb:5PG0|rcsb pdb:5PG1|rcsb pdb:5PG2|rcsb pdb:5PG3|rcsb pdb:5PG4|rcsb pdb:5PG5|rcsb pdb:5PG6|rcsb pdb:5PFM|rcsb pdb:5PG7|rcsb pdb:5PG8|rcsb pdb:5PEQ|rcsb pdb:5PES|rcsb pdb:5PET|rcsb pdb:5PEU|rcsb pdb:5PEV|rcsb pdb:5PEW|rcsb pdb:5PEX|rcsb pdb:5PEY|rcsb pdb:5PEZ|rcsb pdb:5PF0|rcsb pdb:5PF1|rcsb pdb:5PF2|rcsb pdb:5PF3|rcsb pdb:5PF4|rcsb pdb:5PF5|rcsb pdb:5PF6|rcsb pdb:5PF7|rcsb pdb:5PF8|rcsb pdb:5PF9|rcsb pdb:5PFA|rcsb pdb:5PFB|rcsb pdb:5PFC|rcsb pdb:5PFD|rcsb pdb:5PER|rcsb pdb:5PFE|rcsb pdb:5PFF|rcsb pdb:5PFG|rcsb pdb:5PFH|rcsb pdb:5PFI|rcsb pdb:5PFJ|rcsb pdb:5PFL|rcsb pdb:5PG9|rcsb pdb:5PGA|rcsb pdb:5PGB|rcsb pdb:5PGC|rcsb pdb:5PGD|rcsb pdb:5PGE|rcsb pdb:5PGF|rcsb pdb:5PGG|rcsb pdb:5PGH|rcsb pdb:5PGI|rcsb pdb:5PGJ|rcsb pdb:5PGK|rcsb pdb:5PGL|rcsb pdb:5PGN|rcsb pdb:5PGO|rcsb pdb:5PGP|rcsb pdb:5PGQ|rcsb pdb:5PGR|rcsb pdb:5PGS|rcsb pdb:5PGT|rcsb pdb:6FGT|rcsb pdb:6FGU|rcsb pdb:6FH6|rcsb pdb:6FH7|rcsb pdb:6FHQ|rcsb pdb:6FI1|ensembl:ENST00000392782|ensembl:ENSP00000376533|ensembl:ENSP00000376534|refseq:NP_001276904.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:XY+ktagDlhTCiKO++WWFBUqpS4U227377 rogid:KpbxkrPxL1uFuikn8vLISOc4wog9606 rigid:1vlq7GDPBDZ8HCt4LdHzet0EKoU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:Q8NCW5 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-2564619|uniprotkb:B4DGY3|uniprotkb:Q496C6|uniprotkb:Q5T3I2|ensembl:ENSP00000357218|ensembl:ENSP00000505349|ensembl:ENSP00000505899|ensembl:ENSP00000505913|ensembl:ENSP00000506192|ensembl:ENSP00000506275 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:nnre_human(display_long)|uniprotkb:NAXE(gene name)|psi-mi:NAXE(display_short)|uniprotkb:AIBP(gene name synonym)|uniprotkb:APOA1BP(gene name synonym)|uniprotkb:Apolipoprotein A-I-binding protein(gene name synonym)|uniprotkb:"NAD(P)HX epimerase"(gene name synonym)|uniprotkb:YJEFN1(gene name synonym)|uniprotkb:YjeF N-terminal domain-containing protein 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286321|imex:IM-26899-379 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 refseq:NP_658985.2|ensembl:ENST00000679702(transcript)|ensembl:ENST00000680004(transcript)|ensembl:ENST00000680269(transcript)|ensembl:ENST00000681054(transcript)|ensembl:ENST00000681523(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005929"(cilium)|go:"GO:0006869"(lipid transport)|go:"GO:0010874"(regulation of cholesterol efflux)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0031580"(membrane raft distribution)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0046496"(nicotinamide nucleotide metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0052856"(NADHX epimerase activity)|go:"GO:0052857"(NADPHX epimerase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004443(YjeF-related protein, N-terminal)|interpro:IPR032976|interpro:IPR036652|mint:Q8NCW5|reactome:R-HSA-197264|ensembl:ENSG00000163382(gene)|ensembl:ENST00000368235(transcript) - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:Sbye6Tfjl+zVbAgoFH2zdfqe3709606 rigid:7l1sDHaF59xQ8pdpzVoyZhcM6F8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:Q9UIJ7 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-3916527|uniprotkb:Q5VYW6|uniprotkb:Q9NPB4|uniprotkb:Q9H576|uniprotkb:D3DRI1|uniprotkb:Q9HC01|uniprotkb:B4DP58|uniprotkb:E7ET30|ensembl:ENSP00000371230 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:kad3_human(display_long)|uniprotkb:AK3(gene name)|psi-mi:AK3(display_short)|uniprotkb:AK3L1(gene name synonym)|uniprotkb:AK6(gene name synonym)|uniprotkb:AKL3L(gene name synonym)|uniprotkb:Adenylate kinase 3(gene name synonym)|uniprotkb:Adenylate kinase 3 alpha-like 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286315|imex:IM-26899-581 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 refseq:NP_001186781.1|refseq:NP_001186782.1|refseq:NP_001186784.1|refseq:NP_001186785.1|refseq:NP_057366.2|ensembl:ENSG00000147853(gene)|ensembl:ENST00000381809(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006172"(ADP biosynthetic process)|go:"GO:0007596"(blood coagulation)|go:"GO:0009142"(nucleoside triphosphate biosynthetic process)|go:"GO:0046033"(AMP metabolic process)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046041"(ITP metabolic process)|go:"GO:0046051"(UTP metabolic process)|go:"GO:0046899"(nucleoside triphosphate adenylate kinase activity)|go:"GO:0046940"(nucleoside monophosphate phosphorylation)|interpro:IPR000850(Adenylate kinase)|interpro:IPR006259(Adenylate kinase, subfamily)|interpro:IPR007862(Adenylate kinase, zinc-finger lid region)|interpro:IPR028586|interpro:IPR033690|interpro:IPR036193|mint:Q9UIJ7|rcsb pdb:1ZD8|rcsb pdb:6ZJB|rcsb pdb:6ZJD|rcsb pdb:6ZJE|reactome:R-HSA-983231|interpro:IPR027417 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:NDt9xiBjW8L9uXYnyZhVYpVybfA9606 rigid:kSYNWJcKrJbUfiz+ajQ6iyKLmVM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83BF4 uniprotkb:O14818 intact:EBI-21286294|ensemblbacteria:AAO91053 intact:EBI-603272|uniprotkb:Q9BR53|uniprotkb:Q9H4K5|uniprotkb:Q9UEU8|uniprotkb:B2R515|uniprotkb:Q5JXJ2|ensembl:ENSP00000359910 psi-mi:q83bf4_coxbu(display_long)|uniprotkb:CBU_1556(locus name) psi-mi:psa7_human(display_long)|uniprotkb:PSMA7(gene name)|psi-mi:PSMA7(display_short)|uniprotkb:Proteasome subunit RC6-1(gene name synonym)|uniprotkb:Proteasome subunit XAPC7(gene name synonym)|uniprotkb:HSPC(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286301|imex:IM-26899-377 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91053(transcript)|ensemblbacteria:CBU_1556(gene)|go:"GO:0016021"(integral component of membrane)|refseq:NP_820539.1|refseq:WP_010958299.1|mint:Q83BF4 refseq:NP_002783.1|dip:DIP-29363N|ensembl:ENSG00000101182(gene)|ensembl:ENST00000370873(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098794"(postsynapse)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035190|mint:O14818|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:FPvBIpxYSACDYC5jEm0L73i9Pfs227377 rogid:J1M+b+VK02BAn2OnZISjjlmO8dc9606 rigid:11523wBLtCtYbQmaJ8bAbeTMvyo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83BP6 uniprotkb:Q9NUM4 intact:EBI-21286233|ensemblbacteria:AAO90954 intact:EBI-10490807|uniprotkb:Q53FL9|uniprotkb:A4D108|uniprotkb:Q8N4L0|ensembl:ENSP00000379901|ensembl:ENSP00000379902 psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name) psi-mi:t106b_human(display_long)|uniprotkb:TMEM106B(gene name)|psi-mi:TMEM106B(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286288|imex:IM-26899-481 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90954(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|ensemblbacteria:CBU_1457(gene)|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q83BP6 refseq:NP_001127704.1|refseq:NP_060844.2|refseq:XP_005249846.1|ensembl:ENSG00000106460(gene)|ensembl:ENST00000396667(transcript)|ensembl:ENST00000396668(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0007040"(lysosome organization)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051117"(ATPase binding)|go:"GO:0051345"(positive regulation of hydrolase activity)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1905146"(lysosomal protein catabolic process)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR009790(Protein of unknown function DUF1356)|mint:Q9NUM4 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:mIymO86AHiWEAXMs6/mzjWip6QU227377 rogid:RdOP7hFA+H8Tjb/iLZrdShpfJmg9606 rigid:2E6on7dm+wc1nQbR3RKKOx++rjk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83BP6 uniprotkb:O75368 intact:EBI-21286233|ensemblbacteria:AAO90954 intact:EBI-2854777|uniprotkb:Q5JT50|uniprotkb:Q3SYL1|uniprotkb:Q9H0N8|uniprotkb:Q6FIE8|ensembl:ENSP00000362308 psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name) psi-mi:sh3l1_human(display_long)|uniprotkb:SH3BGRL(gene name)|psi-mi:SH3BGRL(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286282|imex:IM-26899-579 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90954(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|ensemblbacteria:CBU_1457(gene)|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q83BP6 refseq:NP_003013.1|ensembl:ENSG00000131171(gene)|ensembl:ENST00000373212(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006993(SH3-binding, glutamic acid-rich protein)|interpro:IPR036249|mint:O75368|rcsb pdb:1U6T|rcsb pdb:1WRY - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:mIymO86AHiWEAXMs6/mzjWip6QU227377 rogid:28tq7yUUsqq+eH3MIo4DoDo/UlA9606 rigid:L7lfGujt4Pq2toJazWb3nI29CWM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83BP6 uniprotkb:O43451 intact:EBI-21286233|ensemblbacteria:AAO90954 intact:EBI-2829774|uniprotkb:Q86UM5|uniprotkb:Q75ME7|uniprotkb:Q0VAX6|ensembl:ENSP00000447378|ensembl:ENSP00000482292 psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name) psi-mi:mga_human(display_long)|uniprotkb:MGAM(gene name)|psi-mi:MGAM(display_short)|uniprotkb:MGA(gene name synonym)|uniprotkb:MGAML(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286276|imex:IM-26899-775 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90954(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|ensemblbacteria:CBU_1457(gene)|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q83BP6 refseq:NP_004659.2|ensembl:ENSG00000257335(gene)|ensembl:ENST00000549489(transcript)|ensembl:ENST00000620571(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004339"(glucan 1,4-alpha-glucosidase activity)|go:"GO:0004553"(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:"GO:0004558"(alpha-1,4-glucosidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005983"(starch catabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0032450"(maltose alpha-glucosidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR000322(Glycoside hydrolase, family 31)|interpro:IPR000519(P-type trefoil)|interpro:IPR011013(Glycoside hydrolase-type carbohydrate-binding)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR017957|interpro:IPR030458|interpro:IPR030459|interpro:IPR031727|mint:O43451|rcsb pdb:2QLY|rcsb pdb:2QMJ|rcsb pdb:3CTT|rcsb pdb:3L4T|rcsb pdb:3L4U|rcsb pdb:3L4V|rcsb pdb:3L4W|rcsb pdb:3L4X|rcsb pdb:3L4Y|rcsb pdb:3L4Z|rcsb pdb:3TON|rcsb pdb:3TOP|reactome:R-HSA-189085|reactome:R-HSA-6798695 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:mIymO86AHiWEAXMs6/mzjWip6QU227377 rogid:99L/qrsHlCvmngN9Oga9OTT0rvo9606 rigid:B0y6eGu0JdDp87FxyfBXEw3UA20 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O95409 uniprotkb:B5QSC8 intact:EBI-7737399|ensembl:ENSP00000365514|uniprotkb:Q9H309|uniprotkb:Q5VYA9|intact:MINT-2798893 intact:EBI-21286181|ensemblbacteria:ACI15292 psi-mi:zic2_human(display_long)|uniprotkb:ZIC2(gene name)|psi-mi:ZIC2(display_short)|uniprotkb:Zinc finger protein of the cerebellum 2(gene name synonym) psi-mi:b5qsc8_coxbu(display_long)|uniprotkb:CBU_1379a(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286227|imex:IM-26899-683 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000043355(gene)|ensembl:ENST00000376335(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007601"(visual perception)|go:"GO:0016604"(nuclear body)|go:"GO:0030154"(cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR041643|mint:O95409|refseq:NP_009060.2 ensemblbacteria:ACI15292(transcript)|ensemblbacteria:CBU_1379a(gene)|go:"GO:0009279"(cell outer membrane)|go:"GO:0015288"(porin activity)|go:"GO:0046930"(pore complex)|refseq:WP_010958188.1|refseq:YP_002333001.1|interpro:IPR011250(Outer membrane protein, beta-barrel)|interpro:IPR000498(Outer membrane protein, OmpA-like, transmembrane region)|mint:B5QSC8 - comment:mint|function:Involved in cerebellar development|function:"Defects in ZIC2 are a cause of holoprosencephaly type 5 (HPE5) [MIM:609637]. Holoprosencephaly (HPE) [MIM:236100] is the most common structural anomaly of the brain, in which the developing forebrain fails to correctly separate into right and left hemispheres. Holoprosencephaly is genetically heterogeneous and associated with several distinct facies and phenotypic variability. Although severe facial anomalies are common in HPE, patients with ZINC2 mutations have relatively normal faces" - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:nap4bAVrW71xdewBlwUIcvLk/vw9606 rogid:XY+ktagDlhTCiKO++WWFBUqpS4U227377 rigid:bHoiISSXKgWzjO0cMSnJsx8FwZo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83BP6 uniprotkb:Q8N128 intact:EBI-21286233|ensemblbacteria:AAO90954 intact:EBI-11043819|uniprotkb:Q68CT2|ensembl:ENSP00000371843|ensembl:ENSP00000379734 psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name) psi-mi:f177a_human(display_long)|uniprotkb:FAM177A1(gene name)|psi-mi:FAM177A1(display_short)|uniprotkb:C14orf24(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286264|imex:IM-26899-773 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90954(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|ensemblbacteria:CBU_1457(gene)|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q83BP6 refseq:NP_001072987.1|refseq:NP_001275951.1|refseq:NP_775878.2|ensembl:ENSG00000151327(gene)|ensembl:ENST00000382406(transcript)|ensembl:ENST00000396472(transcript)|interpro:IPR028260|mint:Q8N128 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:mIymO86AHiWEAXMs6/mzjWip6QU227377 rogid:DFER5JEcKi3kORvFi+DLZ3Ec2PQ9606 rigid:9Qh0awLXRPSX7+J53JWMBUyEehI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83BP6 uniprotkb:P13804 intact:EBI-21286233|ensemblbacteria:AAO90954 intact:EBI-1052886|uniprotkb:B4DT43|uniprotkb:Q53XN3|ensembl:ENSP00000452762 psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name) psi-mi:etfa_human(display_long)|uniprotkb:ETFA(gene name)|psi-mi:ETFA(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286258|imex:IM-26899-253 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90954(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|ensemblbacteria:CBU_1457(gene)|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q83BP6 refseq:NP_000117.1|refseq:NP_001121188.1|dip:DIP-6161N|ensembl:ENSG00000140374(gene)|ensembl:ENST00000557943(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR001308(Electron transfer flavoprotein, alpha subunit)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR014730(Electron transfer flavoprotein, alpha/beta-subunit, N-terminal)|interpro:IPR014731(Electron transfer flavoprotein, alpha subunit, C-terminal)|interpro:IPR018206|interpro:IPR029035|interpro:IPR033947|mint:P13804|rcsb pdb:1EFV|rcsb pdb:1T9G|rcsb pdb:2A1T|rcsb pdb:2A1U|reactome:R-HSA-611105 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:mIymO86AHiWEAXMs6/mzjWip6QU227377 rogid:J2PUTTVN+nd8eHe6TXga+37CiPw9606 rigid:GJbtzeX/G+E5be0dTDeiEZCqq5U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83BP6 uniprotkb:Q08211 intact:EBI-21286233|ensemblbacteria:AAO90954 intact:EBI-352022|intact:EBI-1058470|uniprotkb:Q5VY62|uniprotkb:Q6PD69|uniprotkb:Q99556|uniprotkb:B2RNV4|uniprotkb:Q05CI5|uniprotkb:Q12803|uniprotkb:Q32Q22|ensembl:ENSP00000356520 psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name) psi-mi:dhx9_human(display_long)|uniprotkb:DHX9(gene name)|psi-mi:DHX9(display_short)|uniprotkb:DDX9(gene name synonym)|uniprotkb:NDH2(gene name synonym)|uniprotkb:DExH-box helicase 9(gene name synonym)|uniprotkb:RNA helicase A(gene name synonym)|uniprotkb:LKP(gene name synonym)|uniprotkb:Nuclear DNA helicase II(gene name synonym)|uniprotkb:DEAH box protein 9(gene name synonym)|uniprotkb:Leukophysin(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286252|imex:IM-26899-771 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90954(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|ensemblbacteria:CBU_1457(gene)|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q83BP6 refseq:NP_001348.2|dip:DIP-31504N|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033679"(3'-5' DNA/RNA helicase activity)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0034622"|go:"GO:0035197"(siRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045142"(triplex DNA binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0050691"(regulation of defense response to virus by host)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051028"(mRNA transport)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070269"(pyroptosis)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070922"(small RNA loading onto RISC)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0097165"(nuclear stress granule)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1905172"(RISC complex binding)|go:"GO:1905538"(polysome binding)|go:"GO:1905698"(positive regulation of polysome binding)|go:"GO:1990518"(single-stranded 3'-5' DNA helicase activity)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000765"(regulation of cytoplasmic translation)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR044445|interpro:IPR044446|interpro:IPR044447|mint:Q08211|rcsb pdb:3LLM|rcsb pdb:3VYX|rcsb pdb:3VYY|reactome:R-HSA-1810476|reactome:R-HSA-3134963|reactome:R-HSA-72163|go:"GO:1904973"(positive regulation of viral translation)|ensembl:ENSG00000135829(gene)|ensembl:ENST00000367549(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001069"(regulatory region RNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006260"(DNA replication)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0016604"(nuclear body) - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:mIymO86AHiWEAXMs6/mzjWip6QU227377 rogid:b0VP2Frtvwa9WbYVMwB6TbV2uGU9606 rigid:I0AKLW4CQx+1ic1VTCN+kUC6P/8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83BP6 uniprotkb:O75976 intact:EBI-21286233|ensemblbacteria:AAO90954 intact:EBI-3916308|uniprotkb:B7Z7T9|uniprotkb:B7ZAU4|uniprotkb:F5GZH6|uniprotkb:Q86SH9|uniprotkb:O15377|uniprotkb:Q86XE6|ensembl:ENSP00000225719 psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name) psi-mi:cbpd_human(display_long)|uniprotkb:CPD(gene name)|psi-mi:CPD(display_short)|uniprotkb:Metallocarboxypeptidase D(gene name synonym)|uniprotkb:gp180(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286246|imex:IM-26899-479 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90954(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|ensemblbacteria:CBU_1457(gene)|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q83BP6 refseq:NP_001295.2|refseq:NP_001186704.1|interpro:IPR015567(Peptidase M14B, caboxypeptidase D unit2)|interpro:IPR033848|interpro:IPR034224|mint:O75976|rcsb pdb:5AQ0|reactome:R-HSA-432722|reactome:R-HSA-9696264|reactome:R-HSA-9696273|interpro:IPR008969(Carboxypeptidase-like, regulatory region)|ensembl:ENSG00000108582(gene)|ensembl:ENST00000225719(transcript)|go:"GO:0004181"(metallocarboxypeptidase activity)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006518"(peptide metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016485"(protein processing)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000834(Peptidase M14, carboxypeptidase A) - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:mIymO86AHiWEAXMs6/mzjWip6QU227377 rogid:PC6PFm4D7KoT4utNwyIe57VUwbY9606 rigid:ddSv6iLDQ6X/5ombBRr8OWLBFM8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83BP6 uniprotkb:P02458 intact:EBI-21286233|ensemblbacteria:AAO90954 intact:EBI-2431412|uniprotkb:A6NGA0|uniprotkb:Q14047|uniprotkb:Q14056|uniprotkb:Q14058|uniprotkb:Q16672|uniprotkb:Q1JQ82|uniprotkb:Q12985|uniprotkb:Q14009|uniprotkb:Q14044|uniprotkb:Q14045|uniprotkb:Q14046|uniprotkb:Q9UE41|uniprotkb:Q9UE42|uniprotkb:Q9UE43|uniprotkb:Q6LBY2|uniprotkb:Q6LBY3|uniprotkb:Q96IT5|uniprotkb:Q99227|uniprotkb:Q9UE38|uniprotkb:Q9UE39|uniprotkb:Q9UE40|uniprotkb:Q2V4X7|uniprotkb:Q6LBY1|ensembl:ENSP00000369889 psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name) psi-mi:co2a1_human(display_long)|uniprotkb:COL2A1(gene name)|psi-mi:COL2A1(display_short)|uniprotkb:Alpha-1 type II collagen(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286240|imex:IM-26899-155 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90954(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|ensemblbacteria:CBU_1457(gene)|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q83BP6 refseq:NP_001835.3|refseq:NP_149162.2|ensembl:ENSG00000139219(gene)|ensembl:ENST00000380518(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001502"(cartilage condensation)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001958"(endochondral ossification)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005585"(collagen type II trimer)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006029"(proteoglycan metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030903"(notochord development)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048407"(platelet-derived growth factor binding)|go:"GO:0051216"(cartilage development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060174"(limb bud formation)|go:"GO:0060272"(embryonic skeletal joint morphogenesis)|go:"GO:0060351"(cartilage development involved in endochondral bone morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071599"(otic vesicle development)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0097065"(anterior head development)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000885(Fibrillar collagen, C-terminal)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR008160(Collagen triple helix repeat)|mint:P02458|rcsb pdb:1U5M|rcsb pdb:2FSE|rcsb pdb:2SEB|rcsb pdb:5NIR|rcsb pdb:5OCX|rcsb pdb:5OCY|rcsb pdb:6BIN|rcsb pdb:6NIX|reactome:R-HSA-1442490|reactome:R-HSA-1474244|reactome:R-HSA-1650814|reactome:R-HSA-186797|reactome:R-HSA-198933|reactome:R-HSA-2022090|reactome:R-HSA-216083|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-419037|reactome:R-HSA-8874081|reactome:R-HSA-8948216|go:"GO:0030020"(extracellular matrix structural constituent conferring tensile strength) - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:mIymO86AHiWEAXMs6/mzjWip6QU227377 rogid:T3mQ7b4d6vjE0vl3Kaa09PdldN89606 rigid:6p+OBPTfptcBr45fLrqBGyPTEio false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83BP6 uniprotkb:P06756 intact:EBI-21286233|ensemblbacteria:AAO90954 intact:EBI-298282|ensembl:ENSP00000261023|uniprotkb:A0AV67|uniprotkb:Q53SK4|uniprotkb:Q59EB7|uniprotkb:Q6LD15|uniprotkb:D3DPG8|intact:EBI-10984285|uniprotkb:B0LPF4|uniprotkb:B7Z883|uniprotkb:E7EWZ6|uniprotkb:B7ZLX0 psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name) psi-mi:itav_human(display_long)|uniprotkb:ITGAV(gene name)|psi-mi:ITGAV(display_short)|uniprotkb:VNRA(gene name synonym)|uniprotkb:Vitronectin receptor subunit alpha(gene name synonym)|uniprotkb:MSK8(gene name synonym)|uniprotkb:Vitronectin receptor(gene name synonym)|uniprotkb:VTNR(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286270|imex:IM-26899-255 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90954(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|ensemblbacteria:CBU_1457(gene)|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q83BP6 ensembl:ENSG00000138448(gene)|ensembl:ENST00000261023(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001846"(opsonin binding)|go:"GO:0001968"(fibronectin binding)|go:"GO:0002020"(protease binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008305"(integrin complex)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0009986"(cell surface)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:1990430"(extracellular matrix protein binding)|go:"GO:2000536"(negative regulation of entry of bacterium into host cell)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR018184|interpro:IPR028994|interpro:IPR032695|mint:P06756|rcsb pdb:1JV2|rcsb pdb:1L5G|rcsb pdb:1M1X|rcsb pdb:1U8C|rcsb pdb:3IJE|rcsb pdb:4G1E|rcsb pdb:4G1M|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|go:"GO:1905598"(negative regulation of low-density lipoprotein receptor activity)|rcsb pdb:4O02|rcsb pdb:4UM8|reactome:R-HSA-210990|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-4420097|reactome:R-HSA-445144|reactome:R-HSA-6798695|rcsb pdb:5FFG|rcsb pdb:5FFO|rcsb pdb:5NEM|rcsb pdb:5NER|rcsb pdb:5NET|rcsb pdb:5NEU|rcsb pdb:6AVQ|rcsb pdb:6AVR|rcsb pdb:6AVU|rcsb pdb:6DJP|rcsb pdb:6MK0|rcsb pdb:6MSL|rcsb pdb:6MSU|rcsb pdb:6NAJ|rcsb pdb:6OM1|rcsb pdb:6OM2|rcsb pdb:6UJA|rcsb pdb:6UJB|rcsb pdb:4UM9|rcsb pdb:6UJC|reactome:R-HSA-1236973|reactome:R-HSA-1566948|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0032369"(negative regulation of lipid transport)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0034683"(integrin alphav-beta3 complex)|go:"GO:0034684"(integrin alphav-beta5 complex)|go:"GO:0034685"(integrin alphav-beta6 complex)|go:"GO:0034686"(integrin alphav-beta8 complex)|go:"GO:0035579"(specific granule membrane)|go:"GO:0035866"(alphav-beta3 integrin-PKCalpha complex)|go:"GO:0035867"(alphav-beta3 integrin-IGF-1-IGF1R complex)|go:"GO:0035868"(alphav-beta3 integrin-HMGB1 complex)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0038027"(apolipoprotein A-I-mediated signaling pathway)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0050431"(transforming growth factor beta binding)|go:"GO:0050748"(negative regulation of lipoprotein metabolic process)|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0051057"(positive regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071604"(transforming growth factor beta production)|go:"GO:0085017"(entry into host cell by a symbiont-containing vacuole)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:1901388"(regulation of transforming growth factor beta activation)|go:"GO:1902533"(positive regulation of intracellular signal transduction)|refseq:NP_001138472.1|refseq:NP_002201.1|refseq:NP_001138471.1|dip:DIP-31785N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:mIymO86AHiWEAXMs6/mzjWip6QU227377 rogid:3XbANVuHd/2LJX6zckEV6xx09mY9606 rigid:Cwn/CnzJeVoUMCDZDbAPxQh/tUo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:Q0VDF9 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-8773684|uniprotkb:A8K8F8|uniprotkb:B0YIY9|uniprotkb:Q9P0X2|uniprotkb:Q9UI07|ensembl:ENSP00000367623 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:hsp7e_human(display_long)|uniprotkb:HSPA14(gene name)|psi-mi:HSPA14(display_short)|uniprotkb:HSP60(gene name synonym)|uniprotkb:HSP70L1(gene name synonym)|uniprotkb:HSP70-like protein 1(gene name synonym)|uniprotkb:Heat shock protein HSP60(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286369|imex:IM-26899-483 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 refseq:NP_057383.2|ensembl:ENSG00000187522(gene)|ensembl:ENST00000378372(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051083"('de novo' cotranslational protein folding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR042049|interpro:IPR043129|mint:Q0VDF9|reactome:R-HSA-3371453|dip:DIP-62114N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:RNKKz93Uww+GkRXdvnm5QY8h+lM9606 rigid:FWVbS9yMvt6dQY1NN+DxLig0E6Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:Q9UHY8 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-396453|uniprotkb:Q76LN0|uniprotkb:Q99690|uniprotkb:Q5EBN3|intact:EBI-28984869|ensembl:ENSP00000385112 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:fez2_human(display_long)|uniprotkb:FEZ2(gene name)|psi-mi:FEZ2(display_short)|uniprotkb:Zygin-2(gene name synonym)|uniprotkb:Zygin II(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286363|imex:IM-26899-161 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 refseq:NP_001036013.1|refseq:NP_005093.2|ensembl:ENST00000379245|ensembl:ENSP00000368547|ensembl:ENSP00000385112|ensembl:ENSG00000171055(gene)|ensembl:ENST00000405912(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0030424"(axon)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR011680(FEZ-like)|interpro:IPR015641(Fasciculation and elongation protein zeta 2)|mint:Q9UHY8 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:n5uH+vdgrrvmI+PYkcMUEnAzxwE9606 rigid:Cw2SYO6AqdYhgFWF8z0WDgLcqEI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:Q9C005 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-744973|uniprotkb:D6W578|ensembl:ENSP00000295066|ensembl:ENSP00000345837 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:dpy30_human(display_long)|uniprotkb:DPY30(gene name)|psi-mi:DPY30(display_short)|uniprotkb:Dpy-30-like protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286357|imex:IM-26899-39 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 refseq:NP_115963.1|ensembl:ENSG00000162961(gene)|ensembl:ENST00000295066(transcript)|ensembl:ENST00000342166(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006348"|go:"GO:0016197"(endosomal transport)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|mint:Q9C005|rcsb pdb:3G36|rcsb pdb:4RIQ|rcsb pdb:4RT4|rcsb pdb:4RTA|rcsb pdb:6E2H|rcsb pdb:6PWV|reactome:R-HSA-3214841|reactome:R-HSA-8936459|refseq:NP_001308138.1|dip:DIP-34476N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:yC9NJhTfEIT+YyfWRSJLGbRsQkc9606 rigid:s9gxxhJuj77qftnrAmhYHJTyUrs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:P40227 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286327|imex:IM-26899-157 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606 rigid:XoTQmkiORfo1/84wC7Fk1f/OnxI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:Q14562 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-2511477|ensembl:ENSP00000262415|ensembl:ENSP00000496923 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:dhx8_human(display_long)|uniprotkb:DHX8(gene name)|psi-mi:DHX8(display_short)|uniprotkb:DDX8(gene name synonym)|uniprotkb:DEAH box protein 8(gene name synonym)|uniprotkb:RNA helicase HRH1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286345|imex:IM-26899-159 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 mint:Q14562|rcsb pdb:2EQS|rcsb pdb:3I4U|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:6HYS|rcsb pdb:6HYT|rcsb pdb:6HYU|rcsb pdb:6ICZ|rcsb pdb:6QDV|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0000398"(mRNA splicing, via spliceosome)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR003029(S1, RNA binding)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR022967|interpro:IPR027417|interpro:IPR044762|ensembl:ENSG00000067596(gene)|ensembl:ENST00000262415(transcript)|ensembl:ENST00000650571(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|refseq:NP_004932.1|refseq:NP_001289552.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:ZUmh+KApFNV5NKCq6dizDgnw/Dw9606 rigid:9YBxwe3yUftBuztZR3DQVvIQPMI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:Q13616 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-359390|uniprotkb:O60719|uniprotkb:Q08AL6|uniprotkb:Q8IYW1|uniprotkb:D3DWG3|ensembl:ENSP00000326804|ensembl:ENSP00000387160|ensembl:ENSP00000473318|ensembl:ENSP00000499255|ensembl:ENSP00000499277|ensembl:ENSP00000499398 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:cul1_human(display_long)|uniprotkb:CUL1(gene name)|psi-mi:CUL1(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286339|imex:IM-26899-583 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 refseq:NP_003583.2|rcsb pdb:6WCQ|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7B5R|rcsb pdb:7B5S|reactome:R-HSA-1169091|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|refseq:XP_011514931.1|refseq:XP_011514932.1|refseq:XP_011514933.1|refseq:XP_011514934.1|ensembl:ENSG00000055130(gene)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|ensembl:ENST00000325222(transcript)|ensembl:ENST00000409469(transcript)|ensembl:ENST00000602748(transcript)|ensembl:ENST00000662716(transcript)|ensembl:ENST00000663044(transcript)|ensembl:ENST00000665936(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13616|rcsb pdb:1LDJ|rcsb pdb:1LDK|rcsb pdb:1U6G|rcsb pdb:3RTR|rcsb pdb:3TDU|rcsb pdb:3TDZ|rcsb pdb:4F52|rcsb pdb:4P5O|rcsb pdb:5V89|rcsb pdb:6TTU|refseq:XP_005250117.1|dip:DIP-17013N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:OAZP+ifWW3eEnQKb937ww9s1fMQ9606 rigid:/6jiFn5yNGqnkP0BZvfURoNjVC8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:Q9BWU1 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-394593|uniprotkb:Q5JQZ7|uniprotkb:Q5JR00|uniprotkb:Q8TC78|uniprotkb:Q9UPX2|intact:EBI-28987871|ensembl:ENSP00000357907 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:cdk19_human(display_long)|uniprotkb:CDK19(gene name)|psi-mi:CDK19(display_short)|uniprotkb:CDC2-related protein kinase 6(gene name synonym)|uniprotkb:Death-preventing kinase(gene name synonym)|uniprotkb:Cyclin-dependent kinase 11(gene name synonym)|uniprotkb:CDK11(gene name synonym)|uniprotkb:KIAA1028(gene name synonym)|uniprotkb:CDC2L6(gene name synonym)|uniprotkb:Cell division cycle 2-like protein kinase 6(gene name synonym)|uniprotkb:Cell division protein kinase 19(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286333|imex:IM-26899-381 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 refseq:NP_055891.1|refseq:NP_001287889.1|refseq:NP_001287892.1|refseq:NP_001287893.1|ensembl:ENSG00000155111(gene)|ensembl:ENST00000368911(transcript)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0016592"(mediator complex)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q9BWU1|reactome:R-HSA-1989781|reactome:R-HSA-381340|ensembl:ENST00000323817|ensembl:ENSP00000317665|ensembl:ENSP00000357907|dip:DIP-29013N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:80Ngzl9uqRnqMjGnO5v7j72eY7E9606 rigid:Lewodt4NYLOlyzuzbJewc3XRDtE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:Q9UBP4 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-954409|ensembl:ENSP00000314910|ensembl:ENSP00000379762|ensembl:ENSP00000506835|uniprotkb:Q9ULB7|uniprotkb:A8K1I2|uniprotkb:D3DQW1 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:dkk3_human(display_long)|uniprotkb:REIC(gene name synonym)|uniprotkb:UNQ258/PRO295(orf name)|uniprotkb:DKK3(gene name)|psi-mi:DKK3(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286351|imex:IM-26899-383 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 ensembl:ENSG00000050165(gene)|ensembl:ENST00000326932(transcript)|ensembl:ENST00000396505(transcript)|ensembl:ENST00000683431(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030325"(adrenal gland development)|go:"GO:0032348"(negative regulation of aldosterone biosynthetic process)|go:"GO:0039706"(co-receptor binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1902613"(negative regulation of anti-Mullerian hormone signaling pathway)|go:"GO:2000065"(negative regulation of cortisol biosynthetic process)|interpro:IPR006796(Dickkopf, N-terminal cysteine-rich)|interpro:IPR039863|mint:Q9UBP4|refseq:NP_001018067.1|refseq:NP_037385.2|refseq:NP_056965.3|refseq:XP_006718241.1|refseq:NP_001317149.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:pnbEZP5fAWw3Qxg1gB1sjP0Oyeo9606 rigid:iTJLNNhnsXsWJWxA0SJo2IMGk30 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:O43396 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-1048857|ensembl:ENSP00000217515|ensembl:ENSP00000464918 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:txnl1_human(display_long)|uniprotkb:32 kDa thioredoxin-related protein(gene name synonym)|uniprotkb:TXNL1(gene name)|psi-mi:TXNL1(display_short)|uniprotkb:TRP32(gene name synonym)|uniprotkb:TXL(gene name synonym)|uniprotkb:TXNL(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286411|imex:IM-26899-485 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 refseq:NP_004777.1|ensembl:ENSG00000091164(gene)|ensembl:ENST00000217515(transcript)|ensembl:ENST00000590954(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015036"(disulfide oxidoreductase activity)|interpro:IPR008979(Galactose-binding like)|interpro:IPR010400(Protein of unknown function DUF1000)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|interpro:IPR037047|mint:O43396|rcsb pdb:1GH2|rcsb pdb:1WWY|reactome:R-HSA-9013418|reactome:R-HSA-9013420|reactome:R-HSA-9013422|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:XP_016881582.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:v3qpLTWgZZ1f4Tz/ixVYlSPv7Ro9606 rigid:HDvvd31/ErzVuSKv1Gx+8dHd3L4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:Q9Y2L5 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-2820056|uniprotkb:A0JP15|uniprotkb:B3KME5|uniprotkb:Q9H0L2|ensembl:ENSP00000283351 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:tppc8_human(display_long)|uniprotkb:TRAPPC8(gene name)|psi-mi:TRAPPC8(display_short)|uniprotkb:KIAA1012(gene name synonym)|uniprotkb:Protein TRS85 homolog(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286405|imex:IM-26899-45 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 refseq:NP_055754.2|dip:DIP-48280N|ensembl:ENSG00000153339(gene)|ensembl:ENST00000283351(transcript)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0030008"(TRAPP complex)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:1990072"(TRAPPIII protein complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR024420|mint:Q9Y2L5|reactome:R-HSA-8876198 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:ofBTdvGAgN6zCUIydAmlZ0BpGsw9606 rigid:dYWam1/+vpOjYbTa/WT459gGaWY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:A5PLN9 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-2857298|uniprotkb:Q49A23|uniprotkb:Q4JHG0|uniprotkb:Q17RZ9|uniprotkb:Q6MZG4|uniprotkb:Q8TCM2|uniprotkb:Q9H8I3|ensembl:ENSP00000382367 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:tpc13_human(display_long)|uniprotkb:TRAPPC13(gene name)|psi-mi:TRAPPC13(display_short)|uniprotkb:C5orf44(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286399|imex:IM-26899-685 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 refseq:NP_001087224.1|refseq:NP_001087225.1|refseq:NP_079217.2|refseq:NP_001230666.1|dip:DIP-48284N|ensembl:ENST00000399438(transcript)|go:"GO:0005829"(cytosol)|go:"GO:1990072"(TRAPPIII protein complex)|interpro:IPR010378(Protein of unknown function DUF974)|mint:A5PLN9|reactome:R-HSA-8876198|ensembl:ENSG00000113597(gene) - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:av9WiddXfzAIr65RDo2AXQfWtVk9606 rigid:Hoiyp0ZUuIzQSSVlMdv6ySC0cdU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:P11166 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-717153|uniprotkb:A8K9S6|uniprotkb:O75535|uniprotkb:Q147X2|uniprotkb:B2R620|uniprotkb:D3DPX0|uniprotkb:Q0P512|ensembl:ENSP00000416293 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:gtr1_human(display_long)|uniprotkb:Glucose transporter type 1, erythrocyte/brain(gene name synonym)|uniprotkb:HepG2 glucose transporter(gene name synonym)|uniprotkb:SLC2A1(gene name)|psi-mi:SLC2A1(display_short)|uniprotkb:GLUT1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286393|imex:IM-26899-43 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 refseq:NP_006507.2|ensembl:ENSG00000117394(gene)|ensembl:ENST00000426263(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0001939"(female pronucleus)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0007417"(central nervous system development)|go:"GO:0007565"(female pregnancy)|go:"GO:0014704"(intercalated disc)|go:"GO:0015911"(long-chain fatty acid import across plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019852"(L-ascorbic acid metabolic process)|go:"GO:0019900"(kinase binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030496"(midbody)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032868"(response to insulin)|go:"GO:0033300"(dehydroascorbic acid transmembrane transporter activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0043621"(protein self-association)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0055056"(D-glucose transmembrane transporter activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0072562"(blood microparticle)|go:"GO:0098708"(glucose import across plasma membrane)|go:"GO:0098793"(presynapse)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1904016"(response to Thyroglobulin triiodothyronine)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR002439("Glucose transporter, type 1 (GLUT1)")|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|mint:P11166|rcsb pdb:1SUK|rcsb pdb:4PYP|rcsb pdb:5EQG|rcsb pdb:5EQH|rcsb pdb:5EQI|rcsb pdb:6THA|reactome:R-HSA-189200|reactome:R-HSA-196836|reactome:R-HSA-422356|reactome:R-HSA-5619043|reactome:R-HSA-5653890|dip:DIP-23N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:72DLUG1CFkqcf92goIZBZ4+zuls9606 rigid:WY5Oc046/NVgDKeKObkfHJWbDl8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:Q9NP72 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-722247|uniprotkb:Q53FX8|uniprotkb:Q6FIH1|uniprotkb:B3KMC7|uniprotkb:D3DRW1|intact:EBI-2859793|uniprotkb:Q56UN9|uniprotkb:B7Z333|ensembl:ENSP00000349415|ensembl:ENSP00000507542 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:rab18_human(display_long)|uniprotkb:RAB18(gene name)|psi-mi:RAB18(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286387|imex:IM-26899-163 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 refseq:NP_067075.1|refseq:NP_001243339.1|refseq:NP_001243340.1|refseq:NP_001243341.1|refseq:NP_001243344.1|dip:DIP-60514N|ensembl:ENSG00000099246(gene)|ensembl:ENST00000356940(transcript)|ensembl:ENST00000682082(transcript)|go:"GO:0001654"(eye development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007420"(brain development)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0045202"(synapse)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR025662|interpro:IPR027417|mint:Q9NP72|rcsb pdb:1X3S|reactome:R-HSA-6798695|reactome:R-HSA-6811436|reactome:R-HSA-8873719|reactome:R-HSA-8876198 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:xw6DaP3FsJo34UZC/jqjJEWfSeg9606 rigid:C9x3kaxWGBg1f4y4ff056bvoIA0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:Q9BYG3 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-2561019|ensembl:ENSP00000285814|uniprotkb:Q8TB66|uniprotkb:A8K788|uniprotkb:Q96ED4 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:mk67i_human(display_long)|uniprotkb:NIFK(gene name)|psi-mi:NIFK(display_short)|uniprotkb:MKI67IP(gene name synonym)|uniprotkb:NOPP34(gene name synonym)|uniprotkb:Nucleolar phosphoprotein Nopp34(gene name synonym)|uniprotkb:Nucleolar protein interacting with the FHA domain of pKI-67(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286381|imex:IM-26899-585 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009303"(rRNA transcription)|go:"GO:0016072"(rRNA metabolic process)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021043|interpro:IPR035979|mint:Q9BYG3|rcsb pdb:2AFF|ensembl:ENSG00000155438(gene)|ensembl:ENST00000285814(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000794"(condensed nuclear chromosome)|refseq:NP_115766.3|dip:DIP-28134N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:DUc8AnzFxJjbK+cTW5H83GQcf6o9606 rigid:iPTx8B9DOmpclAawJa4Aiht/jz8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:P53779 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-713543|uniprotkb:A6NFS3|uniprotkb:Q15707|uniprotkb:Q49AP1|uniprotkb:A6NG28|uniprotkb:B3KQ94|ensembl:ENSP00000424154|ensembl:ENSP00000492204|ensembl:ENSP00000492292|ensembl:ENSP00000492903|ensembl:ENSP00000493013|ensembl:ENSP00000493045|ensembl:ENSP00000493072|ensembl:ENSP00000493275|ensembl:ENSP00000493290|ensembl:ENSP00000493363|ensembl:ENSP00000493375|ensembl:ENSP00000493408|ensembl:ENSP00000493435|ensembl:ENSP00000493450 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:mk10_human(display_long)|uniprotkb:Stress-activated protein kinase JNK3(gene name synonym)|uniprotkb:c-Jun N-terminal kinase 3(gene name synonym)|uniprotkb:MAP kinase p49 3F12(gene name synonym)|uniprotkb:MAPK10(gene name)|psi-mi:MAPK10(display_short)|uniprotkb:JNK3(gene name synonym)|uniprotkb:JNK3A(gene name synonym)|uniprotkb:PRKM10(gene name synonym)|uniprotkb:Stress-activated protein kinase 1b(gene name synonym)|uniprotkb:SAPK1B(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286375|imex:IM-26899-41 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 refseq:XP_006714331.1|refseq:XP_005263186.1|refseq:XP_005263187.1|refseq:XP_005263192.1|refseq:NP_002744.1|refseq:NP_620446.1|refseq:NP_620448.1|refseq:NP_001304996.1|refseq:NP_001304997.1|refseq:NP_001304998.1|refseq:XP_011530419.1|refseq:XP_011530420.1|refseq:XP_011530422.1|refseq:XP_011530423.1|refseq:XP_016863908.1|refseq:XP_016863909.1|refseq:XP_016863910.1|refseq:XP_016863912.1|refseq:XP_016863913.1|refseq:XP_016863914.1|refseq:XP_016863915.1|refseq:XP_016863918.1|refseq:XP_016863919.1|refseq:XP_016863920.1|refseq:XP_016863921.1|dip:DIP-1015N|ensembl:ENSG00000109339(gene)|ensembl:ENST00000515400(transcript)|ensembl:ENST00000515650(transcript)|ensembl:ENST00000638313(transcript)|ensembl:ENST00000641051(transcript)|ensembl:ENST00000641066(transcript)|ensembl:ENST00000641157(transcript)|ensembl:ENST00000641207(transcript)|ensembl:ENST00000641341(transcript)|ensembl:ENST00000641462(transcript)|ensembl:ENST00000641647(transcript)|ensembl:ENST00000641823(transcript)|ensembl:ENST00000641902(transcript)|ensembl:ENST00000641952(transcript)|ensembl:ENST00000641983(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004705"(JUN kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007254"(JNK cascade)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009416"(response to light stimulus)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0048511"(rhythmic process)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0090398"(cellular senescence)|go:"GO:0098969"(neurotransmitter receptor transport to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008351(JNK MAP kinase)|interpro:IPR011009(Protein kinase-like)|mint:P53779|rcsb pdb:1JNK|rcsb pdb:1PMN|rcsb pdb:1PMU|rcsb pdb:1PMV|rcsb pdb:2B1P|rcsb pdb:2EXC|rcsb pdb:2O0U|rcsb pdb:2O2U|rcsb pdb:2OK1|rcsb pdb:2P33|rcsb pdb:2R9S|rcsb pdb:2WAJ|rcsb pdb:2ZDT|rcsb pdb:2ZDU|rcsb pdb:3CGF|rcsb pdb:3CGO|rcsb pdb:3DA6|rcsb pdb:3FI2|rcsb pdb:3FI3|rcsb pdb:3FV8|rcsb pdb:3G90|rcsb pdb:3G9L|rcsb pdb:3G9N|rcsb pdb:3KVX|rcsb pdb:3OXI|rcsb pdb:3OY1|rcsb pdb:3PTG|rcsb pdb:3RTP|rcsb pdb:3TTI|rcsb pdb:3TTJ|rcsb pdb:3V6R|rcsb pdb:3V6S|rcsb pdb:4H36|rcsb pdb:4H39|rcsb pdb:4H3B|rcsb pdb:4KKE|rcsb pdb:4KKG|rcsb pdb:4KKH|rcsb pdb:4U79|rcsb pdb:4W4V|rcsb pdb:4W4W|rcsb pdb:4W4X|rcsb pdb:4W4Y|rcsb pdb:4WHZ|rcsb pdb:4X21|rcsb pdb:4Y46|rcsb pdb:4Y5H|rcsb pdb:4Z9L|rcsb pdb:6EKD|rcsb pdb:6EMH|rcsb pdb:6EQ9|rcsb pdb:7KSI|rcsb pdb:7KSJ|rcsb pdb:7KSK|reactome:R-HSA-2559580|reactome:R-HSA-2871796|reactome:R-HSA-450321|reactome:R-HSA-450341 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:dzYzsLACbyCktFnxNeBXEf02BdA9606 rigid:+NdfihVfGv2hJAD3SwTEV6aPNV4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A33 uniprotkb:Q14240 intact:EBI-21286457|ensemblbacteria:AAO91562 intact:EBI-73473|intact:EBI-1058347|uniprotkb:Q96B90|uniprotkb:Q96EA8|intact:EBI-2831835|uniprotkb:Q53XJ6|uniprotkb:D3DNU9|ensembl:ENSP00000326381 psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:if4a2_human(display_long)|uniprotkb:ATP-dependent RNA helicase eIF4A-2(gene name synonym)|uniprotkb:EIF4A2(gene name)|psi-mi:EIF4A2(display_short)|uniprotkb:DDX2B(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286478|imex:IM-26899-167 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 refseq:NP_001958.2|ensembl:ENSG00000156976(gene)|ensembl:ENST00000323963(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900260"(negative regulation of RNA-directed 5'-3' RNA polymerase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|mint:Q14240|rcsb pdb:3BOR|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rogid:m9i/jWfsbU+6kQvj1h06x31+awg9606 rigid:Un1eZGeCoxsMR/JMKMjHGxk53So false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A33 uniprotkb:O00399 intact:EBI-21286457|ensemblbacteria:AAO91562 intact:EBI-2559415|uniprotkb:B2RAC1|ensembl:ENSP00000221114 psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:dctn6_human(display_long)|uniprotkb:DCTN6(gene name)|psi-mi:DCTN6(display_short)|uniprotkb:WS3(gene name synonym)|uniprotkb:Dynactin subunit p27(gene name synonym)|uniprotkb:Protein WS-3(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286472|imex:IM-26899-47 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 refseq:NP_006562.1|ensembl:ENSG00000104671(gene)|ensembl:ENST00000221114(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0070840"(dynein complex binding)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR027777|mint:O00399|rcsb pdb:3TV0|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rogid:+35O26TEIL5l1I7XrNJcl6BA77c9606 rigid:sqWORM+nQHm1D/7ovttVOd/5+x0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A33 uniprotkb:Q86VG3 intact:EBI-21286457|ensemblbacteria:AAO91562 intact:EBI-3923037|uniprotkb:Q96DD6|uniprotkb:D3DR18|ensembl:ENSP00000334848|ensembl:ENSP00000403937|ensembl:ENSP00000431374|ensembl:ENSP00000432685|ensembl:ENSP00000433407|ensembl:ENSP00000483671|ensembl:ENSP00000503448|ensembl:ENSP00000504720 psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:iftap_human(display_long)|uniprotkb:IFTAP(gene name)|psi-mi:IFTAP(display_short)|uniprotkb:C11orf74(gene name synonym)|uniprotkb:NWC(gene name synonym)|uniprotkb:Protein HEPIS(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286466|imex:IM-26899-487 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 ensembl:ENST00000678060(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007340"(acrosome reaction)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0120160"(intraciliary transport particle A binding)|interpro:IPR040028|mint:Q86VG3|ensembl:ENST00000676979(transcript)|refseq:XP_011518187.1|refseq:NP_620142.2|refseq:NP_001263651.1|refseq:NP_001263652.1|refseq:NP_001263653.1|refseq:NP_001263654.1|refseq:NP_001263655.1|refseq:NP_001263656.1|ensembl:ENSG00000166352(gene)|ensembl:ENST00000334307(transcript)|ensembl:ENST00000446510(transcript)|ensembl:ENST00000530697(transcript)|ensembl:ENST00000531554(transcript)|ensembl:ENST00000532470(transcript)|ensembl:ENST00000617650(transcript)|refseq:XP_006718201.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rogid:oLcIB5xXVb7erU+hZ8Bgt//y/4A9606 rigid:Z1cvvBFPc301BH7OaXgKqHVJCKo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83AV9 uniprotkb:Q9UKF6 intact:EBI-21286417|ensemblbacteria:AAO91263 intact:EBI-1044699|uniprotkb:O14769|uniprotkb:Q96F36|uniprotkb:Q53RS2|ensembl:ENSP00000238112 psi-mi:q83av9_coxbu(display_long)|uniprotkb:CBU_1769(locus name) psi-mi:cpsf3_human(display_long)|uniprotkb:Cleavage and polyadenylation specificity factor 73 kDa subunit(gene name synonym)|uniprotkb:mRNA 3'-end-processing endonuclease CPSF-73(gene name synonym)|uniprotkb:CPSF3(gene name)|psi-mi:CPSF3(display_short)|uniprotkb:CPSF73(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286427|imex:IM-26899-165 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91263(transcript)|ensemblbacteria:CBU_1769(gene)|go:"GO:0016787"(hydrolase activity)|rcsb pdb:3TRD|refseq:NP_820749.1|refseq:WP_005770384.1|interpro:IPR029058|interpro:IPR022742|mint:Q83AV9 refseq:NP_057291.1|ensembl:ENSG00000119203(gene)|ensembl:ENST00000238112(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|interpro:IPR021718|interpro:IPR022712|interpro:IPR036866|mint:Q9UKF6|rcsb pdb:2I7T|rcsb pdb:2I7V|rcsb pdb:6M8Q|rcsb pdb:6V4X|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|dip:DIP-42501N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:6GMlP2RFT4dV4vFunFZAsH4xxhI227377 rogid:lpTAUhlcFjFt2tHErN9igCjWTzs9606 rigid:b9O1evsuniJKni/3c2y9LlanW2Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83AV9 uniprotkb:Q9UNK0 intact:EBI-21286417|ensemblbacteria:AAO91263 intact:EBI-727240|uniprotkb:O60712|uniprotkb:Q53XT8|ensembl:ENSP00000305255 psi-mi:q83av9_coxbu(display_long)|uniprotkb:CBU_1769(locus name) psi-mi:stx8_human(display_long)|uniprotkb:STX8(gene name)|psi-mi:STX8(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286445|imex:IM-26899-779 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91263(transcript)|ensemblbacteria:CBU_1769(gene)|go:"GO:0016787"(hydrolase activity)|rcsb pdb:3TRD|refseq:NP_820749.1|refseq:WP_005770384.1|interpro:IPR029058|interpro:IPR022742|mint:Q83AV9 refseq:NP_004844.1|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048278"(vesicle docking)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR041875|mint:Q9UNK0|ensembl:ENSG00000170310(gene)|ensembl:ENST00000306357(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|dip:DIP-47274N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:6GMlP2RFT4dV4vFunFZAsH4xxhI227377 rogid:jdsUOdy99aWRb94ndPtawff7z/o9606 rigid:DdBvFwFNzAmk9PgZZe3VDVANUTY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83AV9 uniprotkb:P42568 intact:EBI-21286417|ensemblbacteria:AAO91263 intact:EBI-716132|uniprotkb:B1AMQ2|uniprotkb:D3DRJ8|intact:EBI-11060385|ensembl:ENSP00000369695|intact:EBI-749963|uniprotkb:B2R7B3|uniprotkb:B7Z755|uniprotkb:Q8IVB0 psi-mi:q83av9_coxbu(display_long)|uniprotkb:CBU_1769(locus name) psi-mi:af9_human(display_long)|uniprotkb:ALL1-fused gene from chromosome 9 protein(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein(gene name synonym)|uniprotkb:YEATS domain-containing protein 3(gene name synonym)|uniprotkb:MLLT3(gene name)|psi-mi:MLLT3(display_short)|uniprotkb:AF9(gene name synonym)|uniprotkb:YEATS3(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286439|imex:IM-26899-385 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91263(transcript)|ensemblbacteria:CBU_1769(gene)|go:"GO:0016787"(hydrolase activity)|rcsb pdb:3TRD|refseq:NP_820749.1|refseq:WP_005770384.1|interpro:IPR029058|interpro:IPR022742|mint:Q83AV9 refseq:NP_004520.2|refseq:NP_001273620.1|ensembl:ENSG00000171843(gene)|ensembl:ENST00000380338(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007379"(segment specification)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010467"(gene expression)|go:"GO:0042393"(histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140030"(modification-dependent protein binding)|go:"GO:1902275"(regulation of chromatin organization)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:2000096"(positive regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR005033(YEATS)|interpro:IPR038704|interpro:IPR040930|mint:P42568|rcsb pdb:2LM0|rcsb pdb:2MV7|rcsb pdb:2N4Q|rcsb pdb:2NDF|rcsb pdb:2NDG|rcsb pdb:4TMP|rcsb pdb:5HJB|rcsb pdb:5HJD|rcsb pdb:5YYF|rcsb pdb:6B7G|rcsb pdb:6L5Z|rcsb pdb:6LS6|rcsb pdb:6MIL|rcsb pdb:6MIM|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|dip:DIP-56409N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:6GMlP2RFT4dV4vFunFZAsH4xxhI227377 rogid:Z+g2iDUI+CzIrL7bMjY11hYKywQ9606 rigid:Jw4jRKtY/dOJpF72TvKqJQ772kw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83AV9 uniprotkb:Q8WVV9 intact:EBI-21286417|ensemblbacteria:AAO91263 intact:EBI-535849|uniprotkb:Q659B9|uniprotkb:Q8IVH5|uniprotkb:Q8IVH6|uniprotkb:Q96HR5|uniprotkb:Q5JB51|uniprotkb:Q53T80|uniprotkb:Q5JB52|ensembl:ENSP00000390625 psi-mi:q83av9_coxbu(display_long)|uniprotkb:CBU_1769(locus name) psi-mi:hnrll_human(display_long)|uniprotkb:HNRNPLL(gene name)|psi-mi:HNRNPLL(display_short)|uniprotkb:HNRPLL(gene name synonym)|uniprotkb:SRRF(gene name synonym)|uniprotkb:Stromal RNA-regulating factor(gene name synonym)|uniprotkb:BLOCK24(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286433|imex:IM-26899-777 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91263(transcript)|ensemblbacteria:CBU_1769(gene)|go:"GO:0016787"(hydrolase activity)|rcsb pdb:3TRD|refseq:NP_820749.1|refseq:WP_005770384.1|interpro:IPR029058|interpro:IPR022742|mint:Q83AV9 refseq:NP_001136122.1|refseq:NP_612403.2|ensembl:ENST00000449105(transcript)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|go:"GO:0003723"(RNA binding)|interpro:IPR034985|go:"GO:0003729"(mRNA binding)|interpro:IPR034986|go:"GO:0005634"(nucleus)|interpro:IPR034987|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:Q8WVV9|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|ensembl:ENSG00000143889(gene) - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:6GMlP2RFT4dV4vFunFZAsH4xxhI227377 rogid:ELIKIpDp+c/Owy7sUJ2M3iYNBGk9606 rigid:dnc1cEvwRU+F2Baghs1fTr1bWKk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83AV9 uniprotkb:Q96TA2 intact:EBI-21286417|ensemblbacteria:AAO91263 intact:EBI-2818916|uniprotkb:Q9UMR9|uniprotkb:Q9H1Q0|uniprotkb:Q5T8D9|uniprotkb:D3DRV8|uniprotkb:D3DRV9|uniprotkb:B4DNM1|intact:EBI-10989776|ensembl:ENSP00000318480 psi-mi:q83av9_coxbu(display_long)|uniprotkb:CBU_1769(locus name) psi-mi:ymel1_human(display_long)|uniprotkb:YME1L1(gene name)|psi-mi:YME1L1(display_short)|uniprotkb:FTSH1(gene name synonym)|uniprotkb:YME1L(gene name synonym)|uniprotkb:ATP-dependent metalloprotease FtsH1(gene name synonym)|uniprotkb:Meg-4(gene name synonym)|uniprotkb:Presenilin-associated metalloprotease(gene name synonym)|uniprotkb:YME1-like protein 1(gene name synonym)|uniprotkb:UNQ1868/PRO4304(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286451|imex:IM-26899-587 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91263(transcript)|ensemblbacteria:CBU_1769(gene)|go:"GO:0016787"(hydrolase activity)|rcsb pdb:3TRD|refseq:NP_820749.1|refseq:WP_005770384.1|interpro:IPR029058|interpro:IPR022742|mint:Q83AV9 refseq:NP_647473.1|refseq:NP_055078.1|refseq:NP_001240795.1|ensembl:ENSG00000136758(gene)|ensembl:ENST00000326799(transcript)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0034214"(protein hexamerization)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0035694"(mitochondrial protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000642(Peptidase M41)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005936(Peptidase M41, FtsH)|interpro:IPR027417|interpro:IPR037219|interpro:IPR041569|mint:Q96TA2|reactome:R-HSA-8949664 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:6GMlP2RFT4dV4vFunFZAsH4xxhI227377 rogid:73ThpwDPUEO7f5SBfSljmbwJLn09606 rigid:gK+3dlTv4YWMqBxSElDXsh9kJos false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A11 uniprotkb:Q9Y4Y9 intact:EBI-21286600|ensemblbacteria:AAO91591 intact:EBI-373007|ensembl:ENSP00000410758 psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name) psi-mi:lsm5_human(display_long)|uniprotkb:LSM5(gene name)|psi-mi:LSM5(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286667|imex:IM-26899-57 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91591(transcript)|ensemblbacteria:CBUA0014(gene)|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047|mint:Q83A11 refseq:NP_001124182.1|refseq:NP_001132971.1|refseq:NP_036454.1|dip:DIP-31162N|ensembl:ENSG00000106355(gene)|ensembl:ENST00000450169(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0009617"(response to bacterium)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR033871|mint:Q9Y4Y9|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377 rogid:EeF2r4qY+BFrZTyTCT+i4ccskf49606 rigid:Hihiq1cO/tD+MDEvgVxrL+UxyDY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A33 uniprotkb:P11021 intact:EBI-21286457|ensemblbacteria:AAO91562 intact:EBI-354921|ensembl:ENSP00000324173|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61 psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286484|imex:IM-26899-781 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 ensembl:ENSG00000044574(gene)|ensembl:ENST00000324460(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006983"(ER overload response)|refseq:NP_005338.1|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042470"(melanosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060904"(regulation of protein folding in endoplasmic reticulum)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903891"(regulation of ATF6-mediated unfolded protein response)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1903897"(regulation of PERK-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-983170|dip:DIP-33189N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606 rigid:q7xvQYnf6GTdMZLnQWFYhePfbds false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A11 uniprotkb:P06858 intact:EBI-21286600|ensemblbacteria:AAO91591 intact:EBI-715909|uniprotkb:Q16282|uniprotkb:Q16283|uniprotkb:Q96FC4|uniprotkb:B2R5T9|ensembl:ENSP00000497642 psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name) psi-mi:lipl_human(display_long)|uniprotkb:LPL(gene name)|psi-mi:LPL(display_short)|uniprotkb:LIPD(gene name synonym)|uniprotkb:Phospholipase A1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286655|imex:IM-26899-55 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91591(transcript)|ensemblbacteria:CBUA0014(gene)|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047|mint:Q83A11 refseq:NP_000228.1|ensembl:ENSG00000175445(gene)|ensembl:ENST00000650287(transcript)|go:"GO:0004465"(lipoprotein lipase activity)|go:"GO:0004620"(phospholipase activity)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0008201"(heparin binding)|go:"GO:0008970"(phospholipase A1 activity)|go:"GO:0009409"(response to cold)|go:"GO:0009749"(response to glucose)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0010890"(positive regulation of sequestering of triglyceride)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016298"(lipase activity)|go:"GO:0017129"(triglyceride binding)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034371"(chylomicron remodeling)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0042493"|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0052739"(phosphatidylserine 1-acylhydrolase activity)|go:"GO:0052740"(1-acyl-2-lysophosphatidylserine acylhydrolase activity)|go:"GO:0055096"(low-density lipoprotein particle mediated signaling)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071813"(lipoprotein particle binding)|go:"GO:1900077"(negative regulation of cellular response to insulin stimulus)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR000734(Lipase)|interpro:IPR001024(Lipoxygenase, LH2)|interpro:IPR002330(Lipoprotein lipase)|interpro:IPR013818(Lipase, N-terminal)|interpro:IPR016272(Lipoprotein lipase, LIPH)|interpro:IPR029058|interpro:IPR033906|interpro:IPR036392|mint:P06858|rcsb pdb:6E7K|rcsb pdb:6OAU|rcsb pdb:6OAZ|rcsb pdb:6OB0|rcsb pdb:6WN4|reactome:R-HSA-381340|reactome:R-HSA-8963889|reactome:R-HSA-8963901|reactome:R-HSA-975634 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377 rogid:PM82k8/f6nyAUhaTSvIUvjVkbYU9606 rigid:pQnQMMnLcirG2hWGLV0SS8DnDH8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A11 uniprotkb:P01116 intact:EBI-21286600|ensemblbacteria:AAO91591 intact:EBI-367415|uniprotkb:P01118|uniprotkb:Q96D10|uniprotkb:B0LPF9|uniprotkb:A8K8Z5|ensembl:ENSP00000256078 psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name) psi-mi:rask_human(display_long)|uniprotkb:KRAS(gene name)|psi-mi:KRAS(display_short)|uniprotkb:RASK2(gene name synonym)|uniprotkb:KRAS2(gene name synonym)|uniprotkb:K-Ras 2(gene name synonym)|uniprotkb:Ki-Ras(gene name synonym)|uniprotkb:c-K-ras(gene name synonym)|uniprotkb:c-Ki-ras(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286649|imex:IM-26899-493 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91591(transcript)|ensemblbacteria:CBUA0014(gene)|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047|mint:Q83A11 refseq:NP_004976.2|refseq:NP_203524.1|refseq:XP_011518955.1|refseq:XP_006719132.1|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032228"(regulation of synaptic transmission, GABAergic)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0035900"(response to isolation stress)|go:"GO:0038002"(endocrine signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|rcsb pdb:6EPL|rcsb pdb:6EPM|rcsb pdb:6EPN|rcsb pdb:6EPO|rcsb pdb:6EPP|rcsb pdb:6F76|rcsb pdb:6FA1|rcsb pdb:6FA2|rcsb pdb:6FA3|rcsb pdb:6FA4|rcsb pdb:6GJ5|rcsb pdb:6GJ6|rcsb pdb:6GJ7|rcsb pdb:6GJ8|rcsb pdb:6GOD|rcsb pdb:6GOE|rcsb pdb:6GOF|rcsb pdb:6GOG|rcsb pdb:6GOM|rcsb pdb:6GQT|rcsb pdb:6GQW|rcsb pdb:6GQX|rcsb pdb:6GQY|rcsb pdb:6H46|rcsb pdb:6H47|rcsb pdb:6JTN|rcsb pdb:6JTO|rcsb pdb:6JTP|rcsb pdb:6M9W|rcsb pdb:6MBQ|rcsb pdb:6MBT|rcsb pdb:6MBU|rcsb pdb:6MNX|rcsb pdb:6MQG|rcsb pdb:6MQN|rcsb pdb:6MS9|rcsb pdb:6MTA|rcsb pdb:6N2J|rcsb pdb:6N2K|rcsb pdb:6O36|rcsb pdb:6O46|rcsb pdb:6O4Y|rcsb pdb:6O4Z|rcsb pdb:6O51|rcsb pdb:6O53|rcsb pdb:6OB2|rcsb pdb:6OB3|rcsb pdb:6OIM|rcsb pdb:6P0Z|rcsb pdb:6E6G|rcsb pdb:6P8W|rcsb pdb:6P8X|rcsb pdb:6P8Y|rcsb pdb:6P8Z|rcsb pdb:6PGO|rcsb pdb:6PGP|rcsb pdb:6PQ3|rcsb pdb:6PTS|rcsb pdb:6PTW|ensembl:ENSG00000133703(gene)|ensembl:ENST00000256078(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007565"(female pregnancy)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008542"(visual learning)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019002"(GMP binding)|go:"GO:0019003"(GDP binding)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0021897"(forebrain astrocyte development)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030275"(LRR domain binding)|rcsb pdb:6QUU|rcsb pdb:6QUV|rcsb pdb:6QUW|rcsb pdb:6QUX|rcsb pdb:6T5B|rcsb pdb:6T5U|rcsb pdb:6T5V|rcsb pdb:6TAM|rcsb pdb:6TAN|rcsb pdb:6USX|rcsb pdb:6USZ|rcsb pdb:6UT0|rcsb pdb:6V5L|rcsb pdb:6V65|rcsb pdb:6V6F|rcsb pdb:6VC8|rcsb pdb:6VJJ|rcsb pdb:6W4E|rcsb pdb:6W4F|rcsb pdb:6WGN|rcsb pdb:6XGU|rcsb pdb:6XGV|rcsb pdb:6XHA|rcsb pdb:6XHB|rcsb pdb:6YR8|rcsb pdb:6YXW|rcsb pdb:6ZL5|rcsb pdb:6ZLI|rcsb pdb:7ACA|rcsb pdb:7ACF|rcsb pdb:7ACH|rcsb pdb:7ACQ|rcsb pdb:7C40|rcsb pdb:7C41|rcsb pdb:7EYX|rcsb pdb:7F0W|rcsb pdb:7KFZ|reactome:R-HSA-112412|reactome:R-HSA-1169092|reactome:R-HSA-1236382|reactome:R-HSA-1250196|reactome:R-HSA-1250347|reactome:R-HSA-1433557|reactome:R-HSA-167044|reactome:R-HSA-171007|reactome:R-HSA-179812|reactome:R-HSA-180336|reactome:R-HSA-186763|reactome:R-HSA-1963640|reactome:R-HSA-210993|reactome:R-HSA-2179392|reactome:R-HSA-2424491|reactome:R-HSA-2428933|reactome:R-HSA-2871796|reactome:R-HSA-375165|reactome:R-HSA-4086398|reactome:R-HSA-442982|reactome:R-HSA-5218921|reactome:R-HSA-5621575|reactome:R-HSA-5637810|reactome:R-HSA-5654688|reactome:R-HSA-5654693|reactome:R-HSA-5654699|reactome:R-HSA-5654700|reactome:R-HSA-5654704|reactome:R-HSA-5654706|reactome:R-HSA-5654712|reactome:R-HSA-5654719|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-5658442|reactome:R-HSA-5673000|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802953|reactome:R-HSA-6802955|reactome:R-HSA-74751|reactome:R-HSA-8849471|reactome:R-HSA-8851805|reactome:R-HSA-8853334|reactome:R-HSA-8853338|reactome:R-HSA-8951936|reactome:R-HSA-9026519|reactome:R-HSA-9027284|reactome:R-HSA-9028731|reactome:R-HSA-9034864|reactome:R-HSA-9607240|reactome:R-HSA-9634285|reactome:R-HSA-9634635|reactome:R-HSA-9648002|reactome:R-HSA-9649913|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9703465|reactome:R-HSA-9703648|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051385"(response to mineralocorticoid)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|mint:P01116|rcsb pdb:1D8D|rcsb pdb:1D8E|rcsb pdb:1KZO|rcsb pdb:1KZP|rcsb pdb:1N4P|rcsb pdb:1N4Q|rcsb pdb:1N4R|rcsb pdb:1N4S|rcsb pdb:3GFT|rcsb pdb:4DSN|rcsb pdb:4DSO|rcsb pdb:4EPR|rcsb pdb:4EPT|rcsb pdb:4EPV|rcsb pdb:4EPW|rcsb pdb:4EPX|rcsb pdb:4EPY|rcsb pdb:4L8G|rcsb pdb:4LDJ|rcsb pdb:4LPK|rcsb pdb:4LRW|rcsb pdb:4LUC|rcsb pdb:4LV6|rcsb pdb:4LYF|rcsb pdb:4LYH|rcsb pdb:4LYJ|rcsb pdb:4M1O|rcsb pdb:4M1S|rcsb pdb:4M1T|rcsb pdb:4M1W|rcsb pdb:4M1Y|rcsb pdb:4M21|rcsb pdb:4M22|rcsb pdb:4NMM|rcsb pdb:4OBE|rcsb pdb:4PZY|rcsb pdb:4PZZ|rcsb pdb:4Q01|rcsb pdb:4Q02|rcsb pdb:4Q03|rcsb pdb:4QL3|rcsb pdb:4TQ9|rcsb pdb:4TQA|rcsb pdb:4WA7|rcsb pdb:5F2E|rcsb pdb:5KYK|rcsb pdb:5MLA|rcsb pdb:5MLB|rcsb pdb:5O2S|rcsb pdb:5O2T|rcsb pdb:5OCG|rcsb pdb:5OCO|rcsb pdb:5OCT|rcsb pdb:5TAR|rcsb pdb:5TB5|rcsb pdb:5UFE|rcsb pdb:5UFQ|rcsb pdb:5UK9|rcsb pdb:5UQW|rcsb pdb:5US4|rcsb pdb:5USJ|rcsb pdb:5V6S|rcsb pdb:5V6V|rcsb pdb:5V71|rcsb pdb:5V9L|rcsb pdb:5V9O|rcsb pdb:5V9U|rcsb pdb:5VBM|rcsb pdb:5VP7|rcsb pdb:5VPI|rcsb pdb:5VPY|rcsb pdb:5VPZ|rcsb pdb:5VQ0|rcsb pdb:5VQ1|rcsb pdb:5VQ2|rcsb pdb:5VQ6|rcsb pdb:5VQ8|rcsb pdb:5W22|rcsb pdb:5WHA|rcsb pdb:5WHB|rcsb pdb:5WHD|rcsb pdb:5WHE|rcsb pdb:5WLB|rcsb pdb:5WPM|rcsb pdb:5XCO|rcsb pdb:5YXZ|rcsb pdb:5YY1|rcsb pdb:6ARK|rcsb pdb:6ASA|rcsb pdb:6ASE|rcsb pdb:6B0V|rcsb pdb:6B0Y|rcsb pdb:6BOF|rcsb pdb:6BP1|rcsb pdb:6CC9|rcsb pdb:6CCH|rcsb pdb:6CCX|rcsb pdb:6CU6|rcsb pdb:6E6F|dip:DIP-33951N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377 rogid:ujXYEgifbSf/thk1UOTW7sKWkX89606 rigid:0LH8uij0dSTkpW/b7qNKJzckulE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A11 uniprotkb:Q0VDF9 intact:EBI-21286600|ensemblbacteria:AAO91591 intact:EBI-8773684|uniprotkb:A8K8F8|uniprotkb:B0YIY9|uniprotkb:Q9P0X2|uniprotkb:Q9UI07|ensembl:ENSP00000367623 psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name) psi-mi:hsp7e_human(display_long)|uniprotkb:HSPA14(gene name)|psi-mi:HSPA14(display_short)|uniprotkb:HSP60(gene name synonym)|uniprotkb:HSP70L1(gene name synonym)|uniprotkb:HSP70-like protein 1(gene name synonym)|uniprotkb:Heat shock protein HSP60(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286643|imex:IM-26899-595 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91591(transcript)|ensemblbacteria:CBUA0014(gene)|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047|mint:Q83A11 refseq:NP_057383.2|ensembl:ENSG00000187522(gene)|ensembl:ENST00000378372(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051083"('de novo' cotranslational protein folding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR042049|interpro:IPR043129|mint:Q0VDF9|reactome:R-HSA-3371453|dip:DIP-62114N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377 rogid:RNKKz93Uww+GkRXdvnm5QY8h+lM9606 rigid:0kzJz0Zm2yCo6PT+HLT9rNx32YM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A11 uniprotkb:P35555 intact:EBI-21286600|ensemblbacteria:AAO91591 intact:EBI-2505934|ensembl:ENSP00000325527|uniprotkb:B2RUU0|uniprotkb:Q15972|uniprotkb:Q75N87|uniprotkb:D2JYH6 psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name) psi-mi:fbn1_human(display_long)|uniprotkb:FBN1(gene name)|psi-mi:FBN1(display_short)|uniprotkb:FBN(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286637|imex:IM-26899-53 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91591(transcript)|ensemblbacteria:CBUA0014(gene)|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047|mint:Q83A11 ensembl:ENSG00000166147(gene)|ensembl:ENST00000316623(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001527"(microfibril)|go:"GO:0001656"(metanephros development)|go:"GO:0005178"(integrin binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0007507"(heart development)|go:"GO:0008201"(heparin binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030023"(extracellular matrix constituent conferring elasticity)|go:"GO:0031012"(extracellular matrix)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034199"(activation of protein kinase A activity)|go:"GO:0035582"(sequestering of BMP in extracellular matrix)|go:"GO:0035583"(sequestering of TGFbeta in extracellular matrix)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0048048"(embryonic eye morphogenesis)|go:"GO:0048050"(post-embryonic eye morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:2001205"(negative regulation of osteoclast development)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011398(Fibrillin)|interpro:IPR017878|interpro:IPR018097|interpro:IPR026823|interpro:IPR036773|interpro:IPR040872|mint:P35555|rcsb pdb:1APJ|rcsb pdb:1EMN|rcsb pdb:1EMO|rcsb pdb:1LMJ|rcsb pdb:1UZJ|rcsb pdb:1UZK|rcsb pdb:1UZP|rcsb pdb:1UZQ|rcsb pdb:2M74|rcsb pdb:2W86|rcsb pdb:5MS9|reactome:R-HSA-1474228|reactome:R-HSA-1566948|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:NP_000129.3|dip:DIP-29985N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377 rogid:YEO0ZRTezrjEAyTaos1pm2hUDXg9606 rigid:+gemyHZCOFt6uevb+oG7XGms4jw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A11 uniprotkb:Q9UBS4 intact:EBI-21286600|ensemblbacteria:AAO91591 intact:EBI-713113|ensembl:ENSP00000265028|ensembl:ENSP00000414398|uniprotkb:Q542Y5|uniprotkb:Q542Y9|uniprotkb:Q6IAQ8|uniprotkb:Q96JC6 psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name) psi-mi:djb11_human(display_long)|uniprotkb:HDJ9(gene name synonym)|uniprotkb:DnaJ protein homolog 9(gene name synonym)|uniprotkb:ER-associated Hsp40 co-chaperone(gene name synonym)|uniprotkb:ER-associated DNAJ(gene name synonym)|uniprotkb:HEDJ(gene name synonym)|uniprotkb:Human DnaJ protein 9(gene name synonym)|uniprotkb:PWP1-interacting protein 4(gene name synonym)|uniprotkb:APOBEC1-binding protein 2(gene name synonym)|uniprotkb:PSEC0121(orf name)|uniprotkb:DNAJB11(gene name)|psi-mi:DNAJB11(display_short)|uniprotkb:EDJ(gene name synonym)|uniprotkb:ERJ3(gene name synonym)|uniprotkb:UNQ537/PRO1080(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 3(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286631|imex:IM-26899-259 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91591(transcript)|ensemblbacteria:CBUA0014(gene)|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047|mint:Q83A11 ensembl:ENSG00000090520(gene)|ensembl:ENST00000265028(transcript)|ensembl:ENST00000439351(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0101031"(chaperone complex)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:Q9UBS4|reactome:R-HSA-381038|go:"GO:0006457"(protein folding)|refseq:NP_057390.1|dip:DIP-29678N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377 rogid:B8jV6uvPmoGzOEpe4qrMiYloSok9606 rigid:OQkxe3/2fP3AN6bNbQcMVISD8aA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A11 uniprotkb:P30085 intact:EBI-21286600|ensemblbacteria:AAO91591 intact:EBI-1053384|uniprotkb:Q53GB7|uniprotkb:Q5SVZ0|uniprotkb:Q96C07|uniprotkb:Q9UBQ8|uniprotkb:Q9UIA2|uniprotkb:B4DPU7|uniprotkb:E9PGI8|intact:EBI-14470672|uniprotkb:B2R6S5 psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name) psi-mi:kcy_human(display_long)|uniprotkb:CMPK(gene name synonym)|uniprotkb:Deoxycytidylate kinase(gene name synonym)|uniprotkb:Uridine monophosphate/cytidine monophosphate kinase(gene name synonym)|uniprotkb:CMPK1(gene name)|psi-mi:CMPK1(display_short)|uniprotkb:CMK(gene name synonym)|uniprotkb:UCK(gene name synonym)|uniprotkb:UMK(gene name synonym)|uniprotkb:UMPK(gene name synonym)|uniprotkb:Nucleoside-diphosphate kinase(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286625|imex:IM-26899-51 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91591(transcript)|ensemblbacteria:CBUA0014(gene)|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047|mint:Q83A11 interpro:IPR027417|refseq:NP_001129612.1|refseq:NP_057392.1|interpro:IPR000850(Adenylate kinase)|interpro:IPR006266(UMP-CMP kinase)|go:"GO:0004127"(cytidylate kinase activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0004849"(uridine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006165"(nucleoside diphosphate phosphorylation)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006225"(UDP biosynthetic process)|go:"GO:0009142"(nucleoside triphosphate biosynthetic process)|go:"GO:0009220"(pyrimidine ribonucleotide biosynthetic process)|go:"GO:0015949"(nucleobase-containing small molecule interconversion)|go:"GO:0033862"(UMP kinase activity)|go:"GO:0036430"(CMP kinase activity)|go:"GO:0036431"(dCMP kinase activity)|go:"GO:0046705"(CDP biosynthetic process)|go:"GO:0050145"(nucleoside monophosphate kinase activity)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:1TEV|rcsb pdb:7E9V|reactome:R-HSA-499943|interpro:IPR033690|mint:P30085 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377 rogid:NUl0+m77fVbeIbhsbRekyl45k0w9606 rigid:PvHPOnB3T36+UfNXDlDFojgUE4o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A11 uniprotkb:P52566 intact:EBI-21286600|ensemblbacteria:AAO91591 intact:EBI-2806617|uniprotkb:B5BU79|ensembl:ENSP00000228945|ensembl:ENSP00000440560|ensembl:ENSP00000444860 psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name) psi-mi:gdir2_human(display_long)|uniprotkb:GDIA2(gene name synonym)|uniprotkb:GDID4(gene name synonym)|uniprotkb:RAP1GN1(gene name synonym)|uniprotkb:Ly-GDI(gene name synonym)|uniprotkb:Rho-GDI beta(gene name synonym)|uniprotkb:ARHGDIB(gene name)|psi-mi:ARHGDIB(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286619|imex:IM-26899-689 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91591(transcript)|ensemblbacteria:CBUA0014(gene)|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047|mint:Q83A11 refseq:NP_001166.3|ensembl:ENSG00000111348(gene)|ensembl:ENST00000541546(transcript)|ensembl:ENST00000541644(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005094"(Rho GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071461"(cellular response to redox state)|go:"GO:1901164"(negative regulation of trophoblast cell migration)|ensembl:ENST00000228945(transcript)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR000406(RHO protein GDP dissociation inhibitor)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR024792|mint:P52566|rcsb pdb:1DS6|rcsb pdb:5H1D|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013423|refseq:NP_001308349.1|refseq:NP_001308350.1|refseq:NP_001308351.1|refseq:NP_001308352.1|dip:DIP-40959N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377 rogid:uiFgGyiT2vBDU0XIRX2ix/bDmHw9606 rigid:HFTYKzMKVSN2aaGenLsvXzqLfJA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q13017 uniprotkb:Q83A11 intact:EBI-7237884|ensembl:ENSP00000371897|ensembl:ENSP00000441692|uniprotkb:Q05BU8|uniprotkb:Q59ER0|uniprotkb:Q6DHZ3|uniprotkb:Q05BE8|uniprotkb:D3DS90|uniprotkb:A8KAA1|intact:MINT-1191615|uniprotkb:D3DS89|uniprotkb:A1L375|uniprotkb:A1L376 intact:EBI-21286600|ensemblbacteria:AAO91591 psi-mi:rhg05_human(display_long)|uniprotkb:ARHGAP5(gene name)|psi-mi:ARHGAP5(display_short)|uniprotkb:RHOGAP5(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 5(gene name synonym)|uniprotkb:p190-B(gene name synonym) psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286613|imex:IM-26899-491 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000371897|ensembl:ENST00000396582|ensembl:ENSP00000379827|ensembl:ENST00000433497|ensembl:ENSP00000407395|ensembl:ENSP00000441692|ensembl:ENST00000556611|ensembl:ENSP00000452222|ensembl:ENSG00000100852(gene)|ensembl:ENST00000345122(transcript)|ensembl:ENST00000539826(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0030879"(mammary gland development)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR001806(Ras GTPase)|interpro:IPR002713(FF)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR032835|interpro:IPR036517|interpro:IPR039006|interpro:IPR039007|mint:Q13017|rcsb pdb:2EE4|rcsb pdb:2EE5|rcsb pdb:5U4V|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_001164.2|refseq:NP_001025226.1|refseq:XP_005267692.1|refseq:XP_005267693.1|refseq:XP_016876776.1|refseq:XP_016876777.1 ensemblbacteria:AAO91591(transcript)|ensemblbacteria:CBUA0014(gene)|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047|mint:Q83A11 - function:GTPase-activating protein for Rho family members. May play a role in the reduction of the p21rasGTPase-activating potential of p120GAP|comment:mint|comment:homomint - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:CcK8+6n27QR+L45eRsmnJP82TQE9606 rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377 rigid:hn0GtHDaGbe0HfuGAqWWwtVkfF0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A11 uniprotkb:Q08AH3 intact:EBI-21286600|ensemblbacteria:AAO91591 intact:EBI-21286556|ensembl:ENSP00000219054|ensembl:ENSP00000379411|ensembl:ENSP00000459451|ensembl:ENSP00000460349|uniprotkb:B3KTT9|uniprotkb:O75202 psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name) psi-mi:acs2a_human(display_long)|uniprotkb:Benzoate--CoA ligase(gene name synonym)|uniprotkb:ACSM2A(gene name)|psi-mi:ACSM2A(display_short)|uniprotkb:ACSM2(gene name synonym)|uniprotkb:MACS2(gene name synonym)|uniprotkb:Acyl-CoA synthetase medium-chain family member 2A(gene name synonym)|uniprotkb:Butyrate--CoA ligase 2A(gene name synonym)|uniprotkb:Butyryl-coenzyme A synthetase 2A(gene name synonym)|uniprotkb:Middle-chain acyl-CoA synthetase 2A(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286607|imex:IM-26899-593 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91591(transcript)|ensemblbacteria:CBUA0014(gene)|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047|mint:Q83A11 ensembl:ENSG00000183747(gene)|ensembl:ENST00000219054(transcript)|ensembl:ENST00000396104(transcript)|ensembl:ENST00000573854(transcript)|ensembl:ENST00000575690(transcript)|go:"GO:0004321"(fatty-acyl-CoA synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006637"(acyl-CoA metabolic process)|go:"GO:0015645"(fatty acid ligase activity)|go:"GO:0018858"(benzoate-CoA ligase activity)|go:"GO:0036112"(medium-chain fatty-acyl-CoA metabolic process)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0046872"(metal ion binding)|go:"GO:0047760"(butyrate-CoA ligase activity)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0102391"(decanoate-CoA ligase activity)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR025110|interpro:IPR042099|mint:Q08AH3|rcsb pdb:2WD9|rcsb pdb:3B7W|rcsb pdb:3C5E|rcsb pdb:3DAY|rcsb pdb:3EQ6|rcsb pdb:3GPC|reactome:R-HSA-177128|rcsb pdb:2VZE|refseq:NP_001295101.1|refseq:NP_001295883.1|refseq:XP_016878412.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377 rogid:DwWZXd/Ir5INoGoRwyGGGasUlnw9606 rigid:Fzfe96jtU4CCjGPTJK5eZoKo9rY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A33 uniprotkb:Q8TAF3 intact:EBI-21286457|ensemblbacteria:AAO91562 intact:EBI-1045469|uniprotkb:Q63HJ2|uniprotkb:Q658Y1|uniprotkb:Q8N3Z1|uniprotkb:Q9NSK8|uniprotkb:Q9P279|uniprotkb:B4DM86|uniprotkb:B4DQI2|uniprotkb:B4DY84|ensembl:ENSP00000307491 psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:wdr48_human(display_long)|uniprotkb:WD repeat endosomal protein(gene name synonym)|uniprotkb:p80(gene name synonym)|uniprotkb:WDR48(gene name)|psi-mi:WDR48(display_short)|uniprotkb:KIAA1449(gene name synonym)|uniprotkb:UAF1(gene name synonym)|uniprotkb:USP1-associated factor 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286550|imex:IM-26899-591 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 refseq:NP_065890.1|ensembl:ENSG00000114742(gene)|ensembl:ENST00000302313(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043588"(skin development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1902525"(regulation of protein monoubiquitination)|go:"GO:1903003"(positive regulation of protein deubiquitination)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021772|interpro:IPR036322|mint:Q8TAF3|rcsb pdb:5CVL|rcsb pdb:5CVN|rcsb pdb:5CVO|rcsb pdb:5K1A|rcsb pdb:5K1B|rcsb pdb:5K1C|rcsb pdb:5L8E|rcsb pdb:5L8W|rcsb pdb:6JLQ|rcsb pdb:7AY0|rcsb pdb:7AY1|rcsb pdb:7AY2|reactome:R-HSA-110314|reactome:R-HSA-5689880|reactome:R-HSA-6783310|reactome:R-HSA-9673766|refseq:NP_001290331.1|refseq:NP_001290332.1|refseq:NP_001333156.1|refseq:NP_001333157.1|dip:DIP-50841N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rogid:S8ihl3jxEEyMS46AM2ynXSFfCU49606 rigid:x8n86EoLhVAxPifCn3xVbYXUAF4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A33 uniprotkb:P40818 intact:EBI-21286457|ensemblbacteria:AAO91562 intact:EBI-1050865|uniprotkb:Q2TB31|uniprotkb:Q7Z3U2|uniprotkb:Q86VA0|uniprotkb:Q8IWI7|ensembl:ENSP00000302239|ensembl:ENSP00000379721|uniprotkb:B4DKA8 psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:ubp8_human(display_long)|uniprotkb:Ubiquitin-specific-processing protease 8(gene name synonym)|uniprotkb:Deubiquitinating enzyme 8(gene name synonym)|uniprotkb:USP8(gene name)|psi-mi:USP8(display_short)|uniprotkb:KIAA0055(gene name synonym)|uniprotkb:UBPY(gene name synonym)|uniprotkb:Ubiquitin isopeptidase Y(gene name synonym)|uniprotkb:Ubiquitin thioesterase 8(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286544|imex:IM-26899-393 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 refseq:NP_001122082.1|refseq:NP_005145.3|refseq:NP_001269978.1|refseq:XP_011520495.1|ensembl:ENSG00000138592(gene)|ensembl:ENST00000307179(transcript)|ensembl:ENST00000396444(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007032"(endosome organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030496"(midbody)|go:"GO:0031313"(extrinsic component of endosome membrane)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0043197"(dendritic spine)|go:"GO:0045296"(cadherin binding)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099576"(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR015063(Region of unknown function DUF1873)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|mint:P40818|rcsb pdb:1WHB|rcsb pdb:2A9U|rcsb pdb:2GFO|rcsb pdb:2GWF|rcsb pdb:3N3K|rcsb pdb:6F09|reactome:R-HSA-1358803|reactome:R-HSA-4641263|reactome:R-HSA-5689880|reactome:R-HSA-6807004|refseq:XP_006720824.1|dip:DIP-40365N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rogid:hpBBzyA4lc9is80ZFJBr1fyEyOM9606 rigid:WtV+mmcLI21539mDxbylBGGwNf0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A33 uniprotkb:Q9Y2L5 intact:EBI-21286457|ensemblbacteria:AAO91562 intact:EBI-2820056|uniprotkb:A0JP15|uniprotkb:B3KME5|uniprotkb:Q9H0L2|ensembl:ENSP00000283351 psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:tppc8_human(display_long)|uniprotkb:TRAPPC8(gene name)|psi-mi:TRAPPC8(display_short)|uniprotkb:KIAA1012(gene name synonym)|uniprotkb:Protein TRS85 homolog(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286538|imex:IM-26899-589 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 refseq:NP_055754.2|dip:DIP-48280N|ensembl:ENSG00000153339(gene)|ensembl:ENST00000283351(transcript)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0030008"(TRAPP complex)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:1990072"(TRAPPIII protein complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR024420|mint:Q9Y2L5|reactome:R-HSA-8876198 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rogid:ofBTdvGAgN6zCUIydAmlZ0BpGsw9606 rigid:v0vfl6yFBiaOd3zRu7ylZPcNsjo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A33 uniprotkb:Q9BS91 intact:EBI-21286457|ensemblbacteria:AAO91562 intact:EBI-18915901|uniprotkb:D3DN66|uniprotkb:Q69YY6|uniprotkb:Q6ZMD6|uniprotkb:Q9NWM9|intact:EBI-28986451|ensembl:ENSP00000417654 psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:s35a5_human(display_long)|uniprotkb:Solute carrier family 35 member A5(gene name synonym)|uniprotkb:UNQ164/PRO190(orf name)|uniprotkb:SLC35A5(gene name)|psi-mi:SLC35A5(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286532|imex:IM-26899-169 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 ensembl:ENSP00000417654|refseq:NP_060415.1|refseq:XP_011511250.1|ensembl:ENSG00000138459(gene)|ensembl:ENST00000492406(transcript)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015165"(pyrimidine nucleotide-sugar transmembrane transporter activity)|go:"GO:0030173"(integral component of Golgi membrane)|interpro:IPR007271(Nucleotide-sugar transporter)|mint:Q9BS91 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rogid:7ncNOFrwj0vIiVZFQNjshXlHU409606 rigid:8UI47S57peLL+NyyR358dUYsnZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A33 uniprotkb:Q8IVG5 intact:EBI-21286457|ensemblbacteria:AAO91562 intact:EBI-2855510|uniprotkb:Q2TV75|uniprotkb:Q8IWI4|uniprotkb:Q2TV71|uniprotkb:A4D1G8|uniprotkb:A0PJG8|uniprotkb:Q8N3L9|uniprotkb:Q2UZV8|uniprotkb:A0JP23|uniprotkb:Q8N875|uniprotkb:A0JP24|uniprotkb:D6W5Q6|ensembl:ENSP00000326247|ensembl:ENSP00000405760|ensembl:ENSP00000408796 psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:sam9l_human(display_long)|uniprotkb:SAMD9L(gene name)|psi-mi:SAMD9L(display_short)|uniprotkb:C7orf6(gene name synonym)|uniprotkb:DRIF2(gene name synonym)|uniprotkb:KIAA2005(gene name synonym)|uniprotkb:UEF(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286526|imex:IM-26899-391 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 refseq:NP_001290425.1|refseq:NP_001290426.1|refseq:NP_001290427.1|refseq:NP_001290429.1|refseq:XP_011514205.1|refseq:XP_006715953.1|refseq:NP_689916.2|refseq:XP_016867311.1|refseq:XP_016867312.1|refseq:XP_005250250.1|ensembl:ENSG00000177409(gene)|ensembl:ENST00000318238(transcript)|ensembl:ENST00000411955(transcript)|ensembl:ENST00000437805(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q8IVG5 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rogid:LeLNrbdYVE3Ch9qGEB0dmf24wMU9606 rigid:u8f6iQlPvQtCaHnIXVr4OtRDaFY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A33 uniprotkb:Q9UHA3 intact:EBI-21286457|ensemblbacteria:AAO91562 intact:EBI-749321|uniprotkb:Q561V8|uniprotkb:Q8N6S8|uniprotkb:Q96B04|uniprotkb:Q96C76|uniprotkb:Q96HJ1|uniprotkb:B2RD72|ensembl:ENSP00000260443 psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:rlp24_human(display_long)|uniprotkb:Ribosomal protein L24-like(gene name synonym)|uniprotkb:RSL24D1(gene name)|psi-mi:RSL24D1(display_short)|uniprotkb:RPL24L(gene name synonym)|uniprotkb:My024(orf name)|uniprotkb:C15orf15(gene name synonym)|uniprotkb:Ribosomal L24 domain-containing protein 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286520|imex:IM-26899-389 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 refseq:NP_057388.1|ensembl:ENSG00000137876(gene)|ensembl:ENST00000260443(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006412"(translation)|go:"GO:1902626"(assembly of large subunit precursor of preribosome)|interpro:IPR000988(Ribosomal protein L24e)|interpro:IPR011017(TRASH)|interpro:IPR023438|interpro:IPR023442|interpro:IPR038630|mint:Q9UHA3|rcsb pdb:6LSS|rcsb pdb:6LU8|go:"GO:0022625"(cytosolic large ribosomal subunit) - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rogid:dP0x5J6G4bPc/7sbV1LIxLNLDn09606 rigid:xhEpTlWiA0tATHq0mEo4hxR00CE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A33 uniprotkb:Q9H0F5 intact:EBI-21286457|ensemblbacteria:AAO91562 intact:EBI-2341200|uniprotkb:Q8N0Y0|uniprotkb:A6PVP9|uniprotkb:B1AM82|uniprotkb:Q7LB33|ensembl:ENSP00000259605|uniprotkb:B1AM81|uniprotkb:B3KSG4|uniprotkb:E7EVL3|uniprotkb:Q9H748 psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:rnf38_human(display_long)|uniprotkb:RING finger protein 38(gene name synonym)|uniprotkb:RNF38(gene name)|psi-mi:RNF38(display_short)|uniprotkb:RING-type E3 ubiquitin transferase RNF38(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286514|imex:IM-26899-49 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 refseq:XP_011516014.1|refseq:XP_011516015.1|refseq:XP_006716784.1|refseq:NP_073618.3|refseq:NP_919309.1|refseq:NP_919310.1|refseq:NP_919311.1|refseq:NP_919313.1|ensembl:ENSG00000137075(gene)|ensembl:ENST00000259605(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008584"(male gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|go:"GO:0036126"(sperm flagellum)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q9H0F5|rcsb pdb:1X4J|rcsb pdb:4V3K|rcsb pdb:4V3L|ensembl:ENSP00000259605|ensembl:ENST00000350199|ensembl:ENSP00000343947|ensembl:ENST00000353739|ensembl:ENSP00000335239|ensembl:ENST00000357058|ensembl:ENSP00000349566|ensembl:ENST00000377877|ensembl:ENSP00000367109|ensembl:ENST00000377885|ensembl:ENSP00000367117|ensembl:ENST00000611646|ensembl:ENSP00000483536|refseq:XP_005251423.1|refseq:XP_005251424.1|refseq:XP_005251425.1|refseq:XP_016869784.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rogid:leJgsTFAtsRhHPh44pbrpk1wkDo9606 rigid:BJicUcaEQyoCjLBfcjejDFmBLnk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A33 uniprotkb:Q6P1N2 intact:EBI-21286457|ensemblbacteria:AAO91562 intact:EBI-21285736 psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:q6p1n2_human(display_long)|uniprotkb:MTIF2(gene name)|psi-mi:MTIF2(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286508|imex:IM-26899-387 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|refseq:NP_001005369.1|refseq:NP_002444.2|interpro:IPR027417|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR015760(Translation initiation factor 2 related)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|mint:Q6P1N2|interpro:IPR044145 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rogid:1tWvOfEeLJfg31GeKiTLztjnehU9606 rigid:NyhX23l9wOLxFz450p0SkgbVaXY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A33 uniprotkb:O43451 intact:EBI-21286457|ensemblbacteria:AAO91562 intact:EBI-2829774|uniprotkb:Q86UM5|uniprotkb:Q75ME7|uniprotkb:Q0VAX6|ensembl:ENSP00000447378|ensembl:ENSP00000482292 psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:mga_human(display_long)|uniprotkb:MGAM(gene name)|psi-mi:MGAM(display_short)|uniprotkb:MGA(gene name synonym)|uniprotkb:MGAML(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286502|imex:IM-26899-257 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 refseq:NP_004659.2|ensembl:ENSG00000257335(gene)|ensembl:ENST00000549489(transcript)|ensembl:ENST00000620571(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004339"(glucan 1,4-alpha-glucosidase activity)|go:"GO:0004553"(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:"GO:0004558"(alpha-1,4-glucosidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005983"(starch catabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0032450"(maltose alpha-glucosidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR000322(Glycoside hydrolase, family 31)|interpro:IPR000519(P-type trefoil)|interpro:IPR011013(Glycoside hydrolase-type carbohydrate-binding)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR017957|interpro:IPR030458|interpro:IPR030459|interpro:IPR031727|mint:O43451|rcsb pdb:2QLY|rcsb pdb:2QMJ|rcsb pdb:3CTT|rcsb pdb:3L4T|rcsb pdb:3L4U|rcsb pdb:3L4V|rcsb pdb:3L4W|rcsb pdb:3L4X|rcsb pdb:3L4Y|rcsb pdb:3L4Z|rcsb pdb:3TON|rcsb pdb:3TOP|reactome:R-HSA-189085|reactome:R-HSA-6798695 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rogid:99L/qrsHlCvmngN9Oga9OTT0rvo9606 rigid:PsRxvM7mjGLZzOUxJEYqAl41V4s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A33 uniprotkb:Q9NR56 intact:EBI-21286457|ensemblbacteria:AAO91562 intact:EBI-2805004|uniprotkb:O43797|uniprotkb:O43311|uniprotkb:Q86UV8|uniprotkb:Q96P92|uniprotkb:Q96RE3|uniprotkb:E9PBW7|uniprotkb:Q86UV9|ensembl:ENSP00000282486|ensembl:ENSP00000418108 psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:mbnl1_human(display_long)|uniprotkb:EXP(gene name synonym)|uniprotkb:KIAA0428(gene name synonym)|uniprotkb:MBNL(gene name synonym)|uniprotkb:Triplet-expansion RNA-binding protein(gene name synonym)|uniprotkb:MBNL1(gene name)|psi-mi:MBNL1(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286496|imex:IM-26899-489 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 refseq:XP_011511149.1|refseq:XP_011511151.1|refseq:NP_001300986.1|refseq:NP_066368.2|refseq:NP_997175.1|refseq:NP_997176.1|refseq:NP_997177.1|refseq:NP_997178.1|refseq:NP_997179.1|refseq:NP_997180.1|refseq:XP_005247523.1|refseq:XP_005247528.1|ensembl:ENSP00000282486|ensembl:ENST00000324196|ensembl:ENSP00000319374|ensembl:ENST00000324210|ensembl:ENSP00000319429|ensembl:ENST00000355460|ensembl:ENSP00000347637|ensembl:ENST00000357472|ensembl:ENSP00000350064|ensembl:ENSP00000418108|ensembl:ENST00000465907|ensembl:ENSP00000417630|ensembl:ENST00000485509|ensembl:ENSP00000418876|ensembl:ENST00000485910|ensembl:ENSP00000418427|ensembl:ENST00000492948|ensembl:ENSP00000420103|ensembl:ENST00000545754|ensembl:ENSP00000437491|interpro:IPR000571(Zinc finger, CCCH-type)|mint:Q9NR56|rcsb pdb:3D2N|rcsb pdb:3D2Q|rcsb pdb:3D2S|rcsb pdb:5U6H|rcsb pdb:5U6L|rcsb pdb:5U9B|go:"GO:0046872"(metal ion binding)|ensembl:ENSG00000152601(gene)|ensembl:ENST00000282486(transcript)|ensembl:ENST00000463374(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001069"(regulatory region RNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007399"(nervous system development)|go:"GO:0008380"(RNA splicing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0045445"(myoblast differentiation)|refseq:XP_016861914.1|refseq:XP_016861915.1|refseq:XP_016861916.1|refseq:XP_016861917.1|refseq:XP_016861918.1|refseq:XP_016861919.1|refseq:XP_016861920.1|refseq:XP_016861925.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rogid:uvyDik76f41mvxO2j/dUD6mKMOk9606 rigid:3jHl2w7+yttAedsS5rm34VfVw38 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A33 uniprotkb:P17301 intact:EBI-21286457|ensemblbacteria:AAO91562 intact:EBI-702960|ensembl:ENSP00000296585|uniprotkb:Q14595 psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:ita2_human(display_long)|uniprotkb:Platelet membrane glycoprotein Ia(gene name synonym)|uniprotkb:Collagen receptor(gene name synonym)|uniprotkb:VLA-2 subunit alpha(gene name synonym)|uniprotkb:CD49 antigen-like family member B(gene name synonym)|uniprotkb:ITGA2(gene name)|psi-mi:ITGA2(display_short)|uniprotkb:CD49B(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286490|imex:IM-26899-687 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 ensembl:ENSG00000164171(gene)|ensembl:ENST00000296585(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002687"(positive regulation of leukocyte migration)|go:"GO:0005178"(integrin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006929"(substrate-dependent cell migration)|go:"GO:0006971"(hypotonic response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007565"(female pregnancy)|go:"GO:0007596"(blood coagulation)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008305"(integrin complex)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0014075"(response to amine)|go:"GO:0014850"(response to muscle activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0030879"(mammary gland development)|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0033343"(positive regulation of collagen binding)|go:"GO:0033591"(response to L-ascorbic acid)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034666"(integrin alpha2-beta1 complex)|go:"GO:0038064"(collagen receptor activity)|go:"GO:0038065"(collagen-activated signaling pathway)|go:"GO:0042493"|go:"GO:0043236"(laminin binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045178"(basal part of cell)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0046872"(metal ion binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050927"(positive regulation of positive chemotaxis)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0071107"(response to parathyroid hormone)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0098639"(collagen binding involved in cell-matrix adhesion)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR018184|interpro:IPR028994|interpro:IPR032695|interpro:IPR036465|mint:P17301|rcsb pdb:1AOX|rcsb pdb:1DZI|rcsb pdb:1PQB|rcsb pdb:1V7P|rcsb pdb:4BJ3|rcsb pdb:5HJ2|rcsb pdb:5THP|rcsb pdb:6ND8|rcsb pdb:6ND9|rcsb pdb:6NDA|rcsb pdb:6NDB|rcsb pdb:6NDC|rcsb pdb:6NDD|rcsb pdb:6NDE|rcsb pdb:6NDF|rcsb pdb:6NDG|rcsb pdb:6NDH|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-447041|reactome:R-HSA-75892|reactome:R-HSA-8874081|refseq:NP_002194.2|dip:DIP-67N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rogid:+18cfTauTEyc6MdRfGpHYfDNEpk9606 rigid:P40hIXq++ZYYBOgSqSc/OS0V9ZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A11 uniprotkb:Q86X45 intact:EBI-21286600|ensemblbacteria:AAO91591 intact:EBI-9379658|uniprotkb:Q13648|uniprotkb:Q4G183|ensembl:ENSP00000429791|ensembl:ENSP00000484634 psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name) psi-mi:daa11_human(display_long)|uniprotkb:DNAAF11(gene name)|psi-mi:DNAAF11(display_short)|uniprotkb:LRRC6(gene name synonym)|uniprotkb:LRTP(gene name synonym)|uniprotkb:Leucine-rich repeat-containing protein 6(gene name synonym)|uniprotkb:Leucine-rich testis-specific protein(gene name synonym)|uniprotkb:Protein tilB homolog(gene name synonym)|uniprotkb:TSLRP(gene name synonym)|uniprotkb:Testis-specific leucine-rich repeat protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286661|imex:IM-26899-783 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91591(transcript)|ensemblbacteria:CBUA0014(gene)|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047|mint:Q83A11 refseq:NP_001308890.1|refseq:NP_001308891.1|refseq:NP_001308892.1|refseq:NP_001308893.1|refseq:NP_001308894.1|refseq:NP_001308895.1|refseq:NP_036604.2|go:"GO:0120293"(dynein axonemal particle)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR007052(CS domain)|interpro:IPR032675|mint:Q86X45|ensembl:ENSG00000129295(gene)|ensembl:ENST00000519595(transcript)|ensembl:ENST00000620350(transcript)|go:"GO:0003341"(cilium movement)|go:"GO:0003351"(epithelial cilium movement involved in extracellular fluid movement)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0008584"(male gonad development)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0031514"(motile cilium)|go:"GO:0036158"(outer dynein arm assembly)|go:"GO:0036159"(inner dynein arm assembly)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0051649"(establishment of localization in cell)|go:"GO:0060287"(epithelial cilium movement involved in determination of left/right asymmetry)|go:"GO:0061458"(reproductive system development)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0070286"(axonemal dynein complex assembly)|go:"GO:0090651"(apical cytoplasm)|go:"GO:0090660"(cerebrospinal fluid circulation)|go:"GO:0120229"(protein localization to motile cilium) - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377 rogid:+KWpDTd1pD7UAK4rVDo5We0inVw9606 rigid:C5QMJe8cVqOAq86QD7CFINKZpkI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83F71 uniprotkb:P80314 intact:EBI-21284995|ensemblbacteria:AAO89644 intact:EBI-772351|uniprotkb:Q9R1U0|ensembl:ENSMUSP00000036288 psi-mi:q83f71_coxbu(display_long)|uniprotkb:CBU_0077(locus name) psi-mi:tcpb_mouse(display_long)|uniprotkb:CCT-beta(gene name synonym)|uniprotkb:Cct2(gene name)|psi-mi:Cct2(display_short)|uniprotkb:Cctb(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286805|imex:IM-26899-791 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO89644(transcript)|ensemblbacteria:CBU_0077(gene)|go:"GO:0016021"(integral component of membrane)|refseq:NP_819130.1|refseq:WP_010957363.1|mint:Q83F71 refseq:NP_031662.2|refseq:XP_006513224.1|dip:DIP-32343N|ensembl:ENSMUSG00000034024(gene)|ensembl:ENSMUST00000047672(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P80314|reactome:R-MMU-390471|reactome:R-MMU-5620922|reactome:R-MMU-6798695|reactome:R-MMU-6814122|reactome:R-MMU-9013418|reactome:R-MMU-9013422 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JKMfHyEgVdel7cHzOgnLRUH7JWo227377 rogid:1CGHdF6g9ZqNbyRmQ5l3eUgD5Ow10090 rigid:N/4CmVBfh782rskr/unzFhEqtlY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A11 uniprotkb:O75970 intact:EBI-21286600|ensemblbacteria:AAO91591 intact:EBI-821405|intact:EBI-2684724|uniprotkb:Q4LE30|uniprotkb:B7ZMI4|uniprotkb:A6NLC2|uniprotkb:O43798|uniprotkb:Q5CZ80|uniprotkb:Q5JTX3|uniprotkb:Q5JTX6|uniprotkb:Q5JTX7|uniprotkb:Q5JUC3|uniprotkb:Q5JUC4|uniprotkb:Q5VZ62|uniprotkb:Q8N790|intact:EBI-10961605|uniprotkb:B2RTS3|ensembl:ENSP00000320006 psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name) psi-mi:mpdz_human(display_long)|uniprotkb:Multi-PDZ domain protein 1(gene name synonym)|uniprotkb:MPDZ(gene name)|psi-mi:MPDZ(display_short)|uniprotkb:MUPP1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286673|imex:IM-26899-261 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91591(transcript)|ensemblbacteria:CBUA0014(gene)|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047|mint:Q83A11 refseq:XP_006716948.1|refseq:XP_006716949.1|refseq:XP_006716950.1|refseq:XP_006716951.1|refseq:XP_006716952.1|refseq:XP_006716954.1|refseq:NP_003820.2|refseq:NP_001248335.1|refseq:NP_001248336.1|refseq:NP_001317566.1|refseq:XP_016870742.1|ensembl:ENSG00000107186(gene)|ensembl:ENST00000319217(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0030425"(dendrite)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR032078|interpro:IPR036034|interpro:IPR036892|mint:O75970|rcsb pdb:2FCF|rcsb pdb:2FNE|rcsb pdb:2IWN|rcsb pdb:2IWO|rcsb pdb:2IWP|rcsb pdb:2IWQ|rcsb pdb:2O2T|rcsb pdb:2OPG|rcsb pdb:2QG1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377 rogid:Q5QzIDHLoL/sWqQI7r/Kb4VLSdY9606 rigid:TazseQ3p2rSrJzT8JyTpcPzlu1A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83FA5 uniprotkb:Q91ZA3 intact:EBI-21284971|ensemblbacteria:AAO89610 intact:EBI-773582|uniprotkb:Q80VU5|uniprotkb:Q922N3|ensembl:ENSMUSP00000038763 psi-mi:y041_coxbu(display_long)|uniprotkb:CBU_0041(locus name) psi-mi:pcca_mouse(display_long)|uniprotkb:"Propanoyl-CoA:carbon dioxide ligase subunit alpha"(gene name synonym)|uniprotkb:Pcca(gene name)|psi-mi:Pcca(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286793|imex:IM-26899-269 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO89610(transcript)|ensemblbacteria:CBU_0041(gene)|refseq:NP_819096.1|refseq:WP_010957340.1|mint:Q83FA5 refseq:NP_659093.2|ensembl:ENSMUSG00000041650(gene)|ensembl:ENSMUST00000038374(transcript)|go:"GO:0004658"(propionyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016421"(CoA carboxylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001882(Biotin-binding site)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR041265|mint:Q91ZA3|reactome:R-MMU-196780|reactome:R-MMU-71032 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:BbqKG2wpwMV+ZnUeGk4QizCbmtI227377 rogid:eqI9nLLrOV7h0emfhPMR6sdbZ2A10090 rigid:B6+9Bcsw2o801P4GKFy8mZBJncI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83FA5 uniprotkb:Q8BG05 intact:EBI-21284971|ensemblbacteria:AAO89610 intact:EBI-2735601|uniprotkb:Q8BHF8|ensembl:ENSMUSP00000088298|ensembl:ENSMUSP00000107595 psi-mi:y041_coxbu(display_long)|uniprotkb:CBU_0041(locus name) psi-mi:roa3_mouse(display_long)|uniprotkb:Hnrnpa3(gene name)|psi-mi:Hnrnpa3(display_short)|uniprotkb:Hnrpa3(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286787|imex:IM-26899-789 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO89610(transcript)|ensemblbacteria:CBU_0041(gene)|refseq:NP_819096.1|refseq:WP_010957340.1|mint:Q83FA5 refseq:NP_444493.1|refseq:NP_666242.2|refseq:NP_932758.1|ensembl:ENSMUSG00000059005(gene)|ensembl:ENSMUST00000090792(transcript)|ensembl:ENSMUST00000111964(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0014069"(postsynaptic density)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0051028"(mRNA transport)|go:"GO:0051033"(RNA transmembrane transporter activity)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034513|interpro:IPR034516|interpro:IPR035979|mint:Q8BG05|reactome:R-MMU-72163|reactome:R-MMU-72203|refseq:XP_011237818.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:BbqKG2wpwMV+ZnUeGk4QizCbmtI227377 rogid:KcZjXvHON9QZSqHWi4nWSDz/HtE10090 rigid:deTNmos9W/7VviID0UTDR7j1DgI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83FA5 uniprotkb:P35802 intact:EBI-21284971|ensemblbacteria:AAO89610 intact:EBI-774131|ensembl:ENSMUSP00000033915 psi-mi:y041_coxbu(display_long)|uniprotkb:CBU_0041(locus name) psi-mi:gpm6a_mouse(display_long)|uniprotkb:Gpm6a(gene name)|psi-mi:Gpm6a(display_short)|uniprotkb:M6a(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286781|imex:IM-26899-497 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO89610(transcript)|ensemblbacteria:CBU_0041(gene)|refseq:NP_819096.1|refseq:WP_010957340.1|mint:Q83FA5 refseq:NP_001240683.1|refseq:NP_001240685.1|refseq:NP_705809.1|ensembl:ENSMUSG00000031517(gene)|ensembl:ENSMUST00000033915(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003407"(neural retina development)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007416"(synapse assembly)|go:"GO:0009617"(response to bacterium)|go:"GO:0030175"(filopodium)|go:"GO:0031175"(neuron projection development)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044295"(axonal growth cone)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|interpro:IPR001614(Myelin proteolipid protein PLP)|interpro:IPR018237|mint:P35802 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:BbqKG2wpwMV+ZnUeGk4QizCbmtI227377 rogid:VjNJpPICJnWhRvbITEMlwqYYedE10090 rigid:H4X/p7MfLLb6yhS0EsAlLGzr9Kc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83FA5 uniprotkb:Q8BWD8 intact:EBI-21284971|ensemblbacteria:AAO89610 intact:EBI-9847870|uniprotkb:Q80TM1|ensembl:ENSMUSP00000040936 psi-mi:y041_coxbu(display_long)|uniprotkb:CBU_0041(locus name) psi-mi:cdk19_mouse(display_long)|uniprotkb:Cdk19(gene name)|psi-mi:Cdk19(display_short)|uniprotkb:Cdc2l6(gene name synonym)|uniprotkb:Kiaa1028(gene name synonym)|uniprotkb:CDC2-related protein kinase 6(gene name synonym)|uniprotkb:Cell division cycle 2-like protein kinase 6(gene name synonym)|uniprotkb:Cell division protein kinase 19(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286775|imex:IM-26899-697 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO89610(transcript)|ensemblbacteria:CBU_0041(gene)|refseq:NP_819096.1|refseq:WP_010957340.1|mint:Q83FA5 refseq:NP_001161776.1|ensembl:ENSMUSG00000038481(gene)|ensembl:ENSMUST00000044672(transcript)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0016592"(mediator complex)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q8BWD8 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:BbqKG2wpwMV+ZnUeGk4QizCbmtI227377 rogid:niA2afLlCitGnmAQiUTOog1ZsuM10090 rigid:yFpoQKG7yK0LytblsTMNX5XRi2c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99MQ4 uniprotkb:Q83FA5 intact:EBI-8412219|intact:MINT-4088506|uniprotkb:Q9D6A2|ensembl:ENSMUSP00000021820|ensembl:ENSMUSP00000136728 intact:EBI-21284971|ensemblbacteria:AAO89610 psi-mi:aspn_mouse(display_long)|uniprotkb:Aspn(gene name)|psi-mi:Aspn(display_short)|uniprotkb:Periodontal ligament-associated protein 1(gene name synonym) psi-mi:y041_coxbu(display_long)|uniprotkb:CBU_0041(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286769|imex:IM-26899-399 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079987.2|refseq:NP_001165952.1|ensembl:ENSMUSG00000021388(gene)|ensembl:ENSMUST00000021820(transcript)|ensembl:ENSMUST00000177948(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0030282"(bone mineralization)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042995"(cell projection)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070171"(negative regulation of tooth mineralization)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR016352(Small leucine-rich proteoglycan, class I, decorin/asporin/byglycan)|interpro:IPR028548|interpro:IPR032675|mint:Q99MQ4 ensemblbacteria:AAO89610(transcript)|ensemblbacteria:CBU_0041(gene)|refseq:NP_819096.1|refseq:WP_010957340.1|mint:Q83FA5 - comment:mint - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:wrlch8StgS/mVuyt7EapTAEeTIo10090 rogid:BbqKG2wpwMV+ZnUeGk4QizCbmtI227377 rigid:H9lnQtG3+x2mKPOgqIkMiO2gavk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83FA5 uniprotkb:P0DMN7 intact:EBI-21284971|ensemblbacteria:AAO89610 intact:EBI-644529|uniprotkb:P31154|uniprotkb:P82184|uniprotkb:Q58E47|ensembl:ENSMUSP00000097528|ensembl:ENSMUSP00000159133 psi-mi:y041_coxbu(display_long)|uniprotkb:CBU_0041(locus name) psi-mi:dcam1_mouse(display_long)|uniprotkb:Amd1(gene name)|psi-mi:Amd1(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286763|imex:IM-26899-495 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO89610(transcript)|ensemblbacteria:CBU_0041(gene)|refseq:NP_819096.1|refseq:WP_010957340.1|mint:Q83FA5 refseq:NP_033795.1|ensembl:ENSMUSG00000075232(gene)|ensembl:ENSMUST00000099945(transcript)|ensembl:ENSMUST00000238969(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004014"(adenosylmethionine decarboxylase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006557"(S-adenosylmethioninamine biosynthetic process)|go:"GO:0006597"(spermine biosynthetic process)|go:"GO:0008295"(spermidine biosynthetic process)|go:"GO:0019810"(putrescine binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001985(S-adenosylmethionine decarboxylase)|interpro:IPR016067(S-adenosylmethionine decarboxylase, core)|interpro:IPR018166|mint:P0DMN7|reactome:R-MMU-351202 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:BbqKG2wpwMV+ZnUeGk4QizCbmtI227377 rogid:C6CwoFWtQAiWB9f5Y+g8jKU0b9g10090 rigid:b1ASYqiZD3NNOpEzkgarw36zluk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A11 uniprotkb:Q15072 intact:EBI-21286600|ensemblbacteria:AAO91591 intact:EBI-11914212|ensembl:ENSP00000392095|ensembl:ENSP00000400391|uniprotkb:Q2TB94 psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name) psi-mi:ozf_human(display_long)|uniprotkb:ZNF146(gene name)|psi-mi:ZNF146(display_short)|uniprotkb:OZF(gene name synonym)|uniprotkb:Only zinc finger protein(gene name synonym)|uniprotkb:Zinc finger protein 146(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286757|imex:IM-26899-695 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91591(transcript)|ensemblbacteria:CBUA0014(gene)|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047|mint:Q83A11 ensembl:ENSG00000167635(gene)|ensembl:ENST00000443387(transcript)|ensembl:ENST00000456324(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008201"(heparin binding)|go:"GO:0008270"(zinc ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q15072|refseq:NP_001093108.1|refseq:NP_001093109.1|refseq:NP_009076.2|refseq:XP_005259271.1|refseq:XP_016882733.1|refseq:XP_016882734.1|refseq:XP_016882735.1|refseq:XP_016882736.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377 rogid:N83ODeBIXcmLguIQ9eBIknUDsCs9606 rigid:pd9CCl2P5Xh2ELn0sQUJSYoB9uA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A11 uniprotkb:Q8IX03 intact:EBI-21286600|ensemblbacteria:AAO91591 intact:EBI-715828|uniprotkb:B4DK05|uniprotkb:O94946|uniprotkb:Q6MZX4|uniprotkb:Q6Y2F8|uniprotkb:Q7Z4G8|uniprotkb:Q8WVM4|uniprotkb:Q9BT29|ensembl:ENSP00000265293 psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name) psi-mi:kibra_human(display_long)|uniprotkb:WW domain-containing protein 1(gene name synonym)|uniprotkb:Kidney and brain protein(gene name synonym)|uniprotkb:HBeAg-binding protein 3(gene name synonym)|uniprotkb:WWC1(gene name)|psi-mi:WWC1(display_short)|uniprotkb:KIAA0869(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286751|imex:IM-26899-599 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91591(transcript)|ensemblbacteria:CBUA0014(gene)|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047|mint:Q83A11 refseq:NP_001155134.1|refseq:NP_056053.1|refseq:NP_001155133.1|ensembl:ENSG00000113645(gene)|ensembl:ENST00000265293(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016477"(cell migration)|go:"GO:0019900"(kinase binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035330"(regulation of hippo signaling)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR036020|interpro:IPR037771|mint:Q8IX03|rcsb pdb:2Z0U|rcsb pdb:6FB4|rcsb pdb:6FD0|rcsb pdb:6FJC|rcsb pdb:6FJD|reactome:R-HSA-2028269|reactome:R-HSA-9013508|dip:DIP-35287N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377 rogid:AGllK9/JguvRQEPw79FYfSgPjiU9606 rigid:YyNNNNN7eRv/MQOaaJZAUwr7cms false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A11 uniprotkb:Q8TAF3 intact:EBI-21286600|ensemblbacteria:AAO91591 intact:EBI-1045469|uniprotkb:Q63HJ2|uniprotkb:Q658Y1|uniprotkb:Q8N3Z1|uniprotkb:Q9NSK8|uniprotkb:Q9P279|uniprotkb:B4DM86|uniprotkb:B4DQI2|uniprotkb:B4DY84|ensembl:ENSP00000307491 psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name) psi-mi:wdr48_human(display_long)|uniprotkb:WD repeat endosomal protein(gene name synonym)|uniprotkb:p80(gene name synonym)|uniprotkb:WDR48(gene name)|psi-mi:WDR48(display_short)|uniprotkb:KIAA1449(gene name synonym)|uniprotkb:UAF1(gene name synonym)|uniprotkb:USP1-associated factor 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286745|imex:IM-26899-693 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91591(transcript)|ensemblbacteria:CBUA0014(gene)|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047|mint:Q83A11 refseq:NP_065890.1|ensembl:ENSG00000114742(gene)|ensembl:ENST00000302313(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043588"(skin development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1902525"(regulation of protein monoubiquitination)|go:"GO:1903003"(positive regulation of protein deubiquitination)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021772|interpro:IPR036322|mint:Q8TAF3|rcsb pdb:5CVL|rcsb pdb:5CVN|rcsb pdb:5CVO|rcsb pdb:5K1A|rcsb pdb:5K1B|rcsb pdb:5K1C|rcsb pdb:5L8E|rcsb pdb:5L8W|rcsb pdb:6JLQ|rcsb pdb:7AY0|rcsb pdb:7AY1|rcsb pdb:7AY2|reactome:R-HSA-110314|reactome:R-HSA-5689880|reactome:R-HSA-6783310|reactome:R-HSA-9673766|refseq:NP_001290331.1|refseq:NP_001290332.1|refseq:NP_001333156.1|refseq:NP_001333157.1|dip:DIP-50841N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377 rogid:S8ihl3jxEEyMS46AM2ynXSFfCU49606 rigid:MD+VMM+Xjaa41NKEwpbePvTPaWs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A11 uniprotkb:O75436 intact:EBI-21286600|ensemblbacteria:AAO91591 intact:EBI-1043891|uniprotkb:Q8TBH4|uniprotkb:Q9H982|ensembl:ENSP00000263559|ensembl:ENSP00000362480|uniprotkb:B2RDD3|uniprotkb:A8MZ56 psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name) psi-mi:vp26a_human(display_long)|uniprotkb:VPS26A(gene name)|psi-mi:VPS26A(display_short)|uniprotkb:VPS26(gene name synonym)|uniprotkb:Vesicle protein sorting 26A(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286739|imex:IM-26899-787 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91591(transcript)|ensemblbacteria:CBUA0014(gene)|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047|mint:Q83A11 ensembl:ENSG00000122958(gene)|ensembl:ENST00000263559(transcript)|ensembl:ENST00000373382(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031982"(vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0097422"(tubular endosome)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR028934|mint:O75436|rcsb pdb:2FAU|rcsb pdb:5F0J|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|reactome:R-HSA-3238698|rcsb pdb:7BLO|refseq:NP_001030337.1|refseq:NP_004887.2|refseq:NP_001305875.1|dip:DIP-29075N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377 rogid:n0uOd+2HQmRW7koIy678uP0d3+o9606 rigid:jFYYeg4AjlMzUhaMh8yGB1OcyU8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A11 uniprotkb:Q9C040 intact:EBI-21286600|ensemblbacteria:AAO91591 intact:EBI-749840|uniprotkb:O60272|uniprotkb:Q9BSI9|uniprotkb:Q9UFZ1|ensembl:ENSP00000415812|ensembl:ENSP00000501586|ensembl:ENSP00000501612|ensembl:ENSP00000501652|ensembl:ENSP00000501662|ensembl:ENSP00000501792|ensembl:ENSP00000501822|ensembl:ENSP00000501951|ensembl:ENSP00000501994|ensembl:ENSP00000502089|ensembl:ENSP00000502114|ensembl:ENSP00000502159|ensembl:ENSP00000502273|ensembl:ENSP00000502348|ensembl:ENSP00000502356|ensembl:ENSP00000502519|ensembl:ENSP00000502543|ensembl:ENSP00000502676|uniprotkb:D3DP09 psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name) psi-mi:trim2_human(display_long)|uniprotkb:RING finger protein 86(gene name synonym)|uniprotkb:TRIM2(gene name)|psi-mi:TRIM2(display_short)|uniprotkb:KIAA0517(gene name synonym)|uniprotkb:RNF86(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM2(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286733|imex:IM-26899-267 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91591(transcript)|ensemblbacteria:CBUA0014(gene)|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047|mint:Q83A11 refseq:NP_001123539.1|refseq:NP_056086.2|ensembl:ENST00000437508(transcript)|ensembl:ENST00000674874(transcript)|ensembl:ENST00000674876(transcript)|ensembl:ENSG00000109654(gene)|refseq:XP_016863433.1|refseq:XP_016863434.1|refseq:XP_016863437.1|refseq:XP_016863438.1|refseq:XP_016863439.1|refseq:XP_016863440.1|refseq:XP_016863441.1|ensembl:ENST00000674976(transcript)|ensembl:ENST00000675054(transcript)|ensembl:ENST00000675159(transcript)|ensembl:ENST00000675293(transcript)|ensembl:ENST00000675315(transcript)|ensembl:ENST00000675384(transcript)|ensembl:ENST00000675745(transcript)|ensembl:ENST00000675835(transcript)|ensembl:ENST00000676172(transcript)|ensembl:ENST00000676252(transcript)|ensembl:ENST00000676264(transcript)|ensembl:ENST00000676348(transcript)|ensembl:ENST00000676374(transcript)|ensembl:ENST00000676423(transcript)|ensembl:ENST00000676458(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR017907|interpro:IPR027370|mint:Q9C040|rcsb pdb:7B2R|reactome:R-HSA-877300|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001258(NHL repeat)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type) - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377 rogid:vcyraMhX0YqrCi9PXhvlJ7QqhGs9606 rigid:D/z8uVXsWVRSm0BFoBjYQSdP5Xg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A11 uniprotkb:Q9Y2L5 intact:EBI-21286600|ensemblbacteria:AAO91591 intact:EBI-2820056|uniprotkb:A0JP15|uniprotkb:B3KME5|uniprotkb:Q9H0L2|ensembl:ENSP00000283351 psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name) psi-mi:tppc8_human(display_long)|uniprotkb:TRAPPC8(gene name)|psi-mi:TRAPPC8(display_short)|uniprotkb:KIAA1012(gene name synonym)|uniprotkb:Protein TRS85 homolog(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286727|imex:IM-26899-265 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91591(transcript)|ensemblbacteria:CBUA0014(gene)|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047|mint:Q83A11 refseq:NP_055754.2|dip:DIP-48280N|ensembl:ENSG00000153339(gene)|ensembl:ENST00000283351(transcript)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0030008"(TRAPP complex)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:1990072"(TRAPPIII protein complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR024420|mint:Q9Y2L5|reactome:R-HSA-8876198 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377 rogid:ofBTdvGAgN6zCUIydAmlZ0BpGsw9606 rigid:f94hRJDUOAkhsI+9A5ZW4LNddhQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y320 uniprotkb:Q83A11 intact:EBI-6447886|ensembl:ENSP00000278422|uniprotkb:B7Z4R4|uniprotkb:Q8NBP9|uniprotkb:Q5J7Q7|uniprotkb:Q561W0|uniprotkb:Q53G73|uniprotkb:Q9H3L1|intact:EBI-7128726|intact:MINT-6945923 intact:EBI-21286600|ensemblbacteria:AAO91591 psi-mi:tmx2_human(display_long)|uniprotkb:Cell proliferation-inducing gene 26 protein(gene name synonym)|uniprotkb:TXNDC14(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 14(gene name synonym)|uniprotkb:CGI-31(orf name)|uniprotkb:My009(orf name)|uniprotkb:PIG26(orf name)|uniprotkb:PSEC0045(orf name)|uniprotkb:UNQ237/PRO270(orf name)|uniprotkb:TMX2(gene name)|psi-mi:TMX2(display_short) psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286721|imex:IM-26899-597 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000213593(gene)|ensembl:ENST00000278422(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007420"(brain development)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043227"(membrane-bounded organelle)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR037463|interpro:IPR039101|mint:Q9Y320|rcsb pdb:2DJ0|refseq:NP_001137484.1|refseq:NP_057043.1 ensemblbacteria:AAO91591(transcript)|ensemblbacteria:CBUA0014(gene)|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047|mint:Q83A11 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:5YbR806GhogQ2yI3r9uo8i97MzY9606 rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377 rigid:A8yf6pgm50AAh4o4ZA118lqcwf4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y3A6 uniprotkb:Q83A11 intact:EBI-7560959|intact:MINT-3085589|uniprotkb:B2R703|uniprotkb:D3DT38|uniprotkb:Q96AX8|uniprotkb:B1AKT4|ensembl:ENSP00000359305 intact:EBI-21286600|ensemblbacteria:AAO91591 psi-mi:tmed5_human(display_long)|uniprotkb:TMED5(gene name)|psi-mi:TMED5(display_short)|uniprotkb:p24 family protein gamma-2(gene name synonym)|uniprotkb:p28(gene name synonym)|uniprotkb:CGI-100(orf name)|uniprotkb:UNQ397/PRO733(orf name) psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286715|imex:IM-26899-263 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001161302.1|refseq:NP_057124.3|ensembl:ENSG00000117500(gene)|ensembl:ENST00000370282(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090161"(Golgi ribbon formation)|interpro:IPR009038(GOLD)|interpro:IPR015717(ST2 receptor binding protein related)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|mint:Q9Y3A6|reactome:R-HSA-3238698 ensemblbacteria:AAO91591(transcript)|ensemblbacteria:CBUA0014(gene)|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047|mint:Q83A11 - comment:mint|comment:homomint - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:3XAcqSucHNP4F3ilaBFRMSQ1B8Q9606 rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377 rigid:KH4TMMEnqBDrFOQygwRIVFlmg1Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A11 uniprotkb:Q8TCU3 intact:EBI-21286600|ensemblbacteria:AAO91591 intact:EBI-21285839|ensembl:ENSP00000297524|uniprotkb:Q05C37|uniprotkb:Q08AH9|uniprotkb:Q96N84 psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name) psi-mi:s7a13_human(display_long)|uniprotkb:SLC7A13(gene name)|psi-mi:SLC7A13(display_short)|uniprotkb:AGT1(gene name synonym)|uniprotkb:XAT2(gene name synonym)|uniprotkb:Sodium-independent aspartate/glutamate transporter 1(gene name synonym)|uniprotkb:X-amino acid transporter 2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286709|imex:IM-26899-397 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91591(transcript)|ensemblbacteria:CBUA0014(gene)|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047|mint:Q83A11 ensembl:ENSG00000164893(gene)|ensembl:ENST00000297524(transcript)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0015811"(L-cystine transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR002293(Amino acid/polyamine transporter I)|mint:Q8TCU3|refseq:NP_620172.2 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377 rogid:W8HPrBO1TnsueOONPohwDYH1z9c9606 rigid:KWSuenLRpAmDKTahEzkfP3DLtlY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A11 uniprotkb:Q96EE3 intact:EBI-21286600|ensemblbacteria:AAO91591 intact:EBI-922818|uniprotkb:Q8NFU6|uniprotkb:Q96MH3|uniprotkb:Q9C069|uniprotkb:A8K5B1|ensembl:ENSP00000262124 psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name) psi-mi:seh1_human(display_long)|uniprotkb:Nup107-160 subcomplex subunit SEH1(gene name synonym)|uniprotkb:SEH1L(gene name)|psi-mi:SEH1L(display_short)|uniprotkb:SEC13L(gene name synonym)|uniprotkb:SEH1(gene name synonym)|uniprotkb:SEC13-like protein(gene name synonym)|uniprotkb:GATOR complex protein SEH1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286703|imex:IM-26899-691 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91591(transcript)|ensemblbacteria:CBUA0014(gene)|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047|mint:Q83A11 refseq:NP_001013455.1|refseq:NP_112493.2|ensembl:ENSP00000262124|ensembl:ENST00000399892|ensembl:ENSP00000382779|ensembl:ENSG00000085415(gene)|ensembl:ENST00000262124(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0015031"(protein transport)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034629"|go:"GO:0035859"(Seh1-associated complex)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0061700"(GATOR2 complex)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|interpro:IPR037363|interpro:IPR037597|mint:Q96EE3|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9639288|reactome:R-HSA-9648025 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377 rogid:I/aUTa3zTawK6QwtkrUkO8B51W49606 rigid:exO1mUKsun3zBaBe+OvecG8A3wU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A11 uniprotkb:O95104 intact:EBI-21286600|ensemblbacteria:AAO91591 intact:EBI-2854897|uniprotkb:Q6P1M5|uniprotkb:Q8N3I8|uniprotkb:Q9ULP8|uniprotkb:Q0P5W8|uniprotkb:Q9UFM1|uniprotkb:C9JLZ0|ensembl:ENSP00000286835 psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name) psi-mi:scaf4_human(display_long)|uniprotkb:SCAF4(gene name)|psi-mi:SCAF4(display_short)|uniprotkb:Splicing factor, arginine/serine-rich 15(gene name synonym)|uniprotkb:SFRS15(gene name synonym)|uniprotkb:KIAA1172(gene name synonym)|uniprotkb:CTD-binding SR-like protein RA4(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286697|imex:IM-26899-395 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91591(transcript)|ensemblbacteria:CBUA0014(gene)|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047|mint:Q83A11 refseq:NP_001138916.1|refseq:NP_001138917.1|refseq:NP_065757.1|ensembl:ENSG00000156304(gene)|ensembl:ENST00000286835(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2000805"("negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled")|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034369|interpro:IPR035979|mint:O95104|rcsb pdb:6XKB - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377 rogid:l++VfjjY/kfVHl+bhXTWsyyL4Zc9606 rigid:DwSWvL/KJ1MFRBZtkXitDT9KW6k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A11 uniprotkb:Q96PU8 intact:EBI-21286600|ensemblbacteria:AAO91591 intact:EBI-945792|uniprotkb:Q2I375|uniprotkb:Q5MJQ1|uniprotkb:Q969L9|uniprotkb:Q96EJ3|uniprotkb:Q96KA3|uniprotkb:Q96PU6|uniprotkb:Q96PU7|uniprotkb:Q9P0X6|uniprotkb:Q9P0X7|uniprotkb:Q9P0X8|uniprotkb:Q9P0X9|uniprotkb:Q9P0Y0|uniprotkb:Q9P0Y1|ensembl:ENSP00000355094 psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name) psi-mi:qki_human(display_long)|uniprotkb:QKI(gene name)|psi-mi:QKI(display_short)|uniprotkb:HKQ(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286691|imex:IM-26899-59 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91591(transcript)|ensemblbacteria:CBUA0014(gene)|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047|mint:Q83A11 refseq:NP_006766.1|refseq:NP_996735.1|refseq:NP_996736.1|refseq:NP_996737.1|refseq:NP_001288014.1|refseq:XP_011534561.1|ensembl:ENSG00000112531(gene)|ensembl:ENST00000361752(transcript)|go:"GO:0001570"(vasculogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0007286"(spermatid development)|go:"GO:0008380"(RNA splicing)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0042552"(myelination)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042759"(long-chain fatty acid biosynthetic process)|go:"GO:0045202"(synapse)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0051028"(mRNA transport)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032367|interpro:IPR032377|interpro:IPR036612|mint:Q96PU8|rcsb pdb:4JVH|reactome:R-HSA-6802952 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377 rogid:7dcw5OyNAhQTE+yTch3qbSlZJdE9606 rigid:1Vo3ByC/a8MYYiDTHfje6xu4f0g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A11 uniprotkb:O14818 intact:EBI-21286600|ensemblbacteria:AAO91591 intact:EBI-603272|uniprotkb:Q9BR53|uniprotkb:Q9H4K5|uniprotkb:Q9UEU8|uniprotkb:B2R515|uniprotkb:Q5JXJ2|ensembl:ENSP00000359910 psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name) psi-mi:psa7_human(display_long)|uniprotkb:PSMA7(gene name)|psi-mi:PSMA7(display_short)|uniprotkb:Proteasome subunit RC6-1(gene name synonym)|uniprotkb:Proteasome subunit XAPC7(gene name synonym)|uniprotkb:HSPC(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286685|imex:IM-26899-785 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91591(transcript)|ensemblbacteria:CBUA0014(gene)|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047|mint:Q83A11 refseq:NP_002783.1|dip:DIP-29363N|ensembl:ENSG00000101182(gene)|ensembl:ENST00000370873(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098794"(postsynapse)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035190|mint:O14818|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377 rogid:J1M+b+VK02BAn2OnZISjjlmO8dc9606 rigid:g6fZeT05hdGYDRj+PbQWbsxvVp0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A11 uniprotkb:Q86UE4 intact:EBI-21286600|ensemblbacteria:AAO91591 intact:EBI-1046588|ensembl:ENSP00000338235|uniprotkb:Q8TCX3|uniprotkb:Q6PK07|uniprotkb:Q05DH2|uniprotkb:Q52QU9 psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name) psi-mi:lyric_human(display_long)|uniprotkb:Lysine-rich CEACAM1 co-isolated protein(gene name synonym)|uniprotkb:3D3/LYRIC(gene name synonym)|uniprotkb:Metastasis adhesion protein(gene name synonym)|uniprotkb:Astrocyte elevated gene-1 protein(gene name synonym)|uniprotkb:MTDH(gene name)|psi-mi:MTDH(display_short)|uniprotkb:AEG1(gene name synonym)|uniprotkb:LYRIC(gene name synonym)|uniprotkb:Metadherin(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286679|imex:IM-26899-171 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91591(transcript)|ensemblbacteria:CBUA0014(gene)|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047|mint:Q83A11 ensembl:ENSG00000147649(gene)|ensembl:ENST00000336273(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046581"(intercellular canaliculus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070830"(bicellular tight junction assembly)|interpro:IPR031402|mint:Q86UE4|rcsb pdb:4QMG|refseq:NP_848927.2 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377 rogid:daZhKhAOeoKGjfl0IXt1fZXn/I09606 rigid:9Gmxkz40QLtVM5FHtifxFjRwgRg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83F71 uniprotkb:Q80UL9 intact:EBI-21284995|ensemblbacteria:AAO89644 intact:EBI-15904062|ensembl:ENSMUSP00000052033|ensembl:ENSMUSP00000150697|uniprotkb:E9QNV7|uniprotkb:Q5DTC4 psi-mi:q83f71_coxbu(display_long)|uniprotkb:CBU_0077(locus name) psi-mi:jaml_mouse(display_long)|uniprotkb:Jaml(gene name)|psi-mi:Jaml(display_short)|uniprotkb:Amica1(gene name synonym)|uniprotkb:Gm638(gene name synonym)|uniprotkb:Dendritic cell-specific protein CREA7(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286799|imex:IM-26899-173 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO89644(transcript)|ensemblbacteria:CBU_0077(gene)|go:"GO:0016021"(integral component of membrane)|refseq:NP_819130.1|refseq:WP_010957363.1|mint:Q83F71 ensembl:ENSMUSG00000048534(gene)|ensembl:ENSMUST00000050020(transcript)|ensembl:ENSMUST00000215880(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0035696"(monocyte extravasation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046629"(gamma-delta T cell activation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0060054"(positive regulation of epithelial cell proliferation involved in wound healing)|go:"GO:0072672"(neutrophil extravasation)|interpro:IPR000920(Myelin P0 protein)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR029871|interpro:IPR036179|mint:Q80UL9|rcsb pdb:3MJ6|rcsb pdb:3MJ7|rcsb pdb:3MJ9|reactome:R-MMU-198933|reactome:R-MMU-202733|refseq:NP_001005421.3|refseq:XP_006510446.1|dip:DIP-59107N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JKMfHyEgVdel7cHzOgnLRUH7JWo227377 rogid:wyMSTohBNctQ6300aeYqZ06w9qY10090 rigid:MJ9ApyA5T5HimvraeSCl1sw6bBs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83EM2 uniprotkb:Q69ZT3 intact:EBI-21285149|ensemblbacteria:AAO89852 intact:EBI-21286851 psi-mi:q83em2_coxbu(display_long)|uniprotkb:CBU_0295(locus name) psi-mi:q69zt3_mouse(display_long)|uniprotkb:Trappc8(gene name)|psi-mi:Trappc8(display_short)|uniprotkb:mKIAA1012(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286869|imex:IM-26899-61 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO89852(transcript)|ensemblbacteria:CBU_0295(gene)|refseq:NP_819338.1|refseq:WP_010957484.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q83EM2 go:"GO:0000407"(phagophore assembly site)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0030008"(TRAPP complex)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:1990072"(TRAPPIII protein complex)|refseq:NP_796012.2|interpro:IPR024420|mint:Q69ZT3 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:93t8PoA8XuYP8WAnEuBgVdP88/U227377 rogid:LagbN8RAOyPiWe/FNywzeyngNUI10090 rigid:wTLHF9GwHJTOwOF9ROTLE+kvdxI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D1D4 uniprotkb:Q83F71 intact:EBI-6999360|ensembl:ENSMUSP00000037583|uniprotkb:Q6P227|uniprotkb:Q3U7I7|intact:MINT-1863252|uniprotkb:Q922U8 intact:EBI-21284995|ensemblbacteria:AAO89644 psi-mi:tmeda_mouse(display_long)|uniprotkb:Tmed10(gene name)|psi-mi:Tmed10(display_short)|uniprotkb:Tmp21(gene name synonym)|uniprotkb:21 kDa transmembrane-trafficking protein(gene name synonym)|uniprotkb:Transmembrane protein Tmp21(gene name synonym)|uniprotkb:p24 family protein delta-1(gene name synonym) psi-mi:q83f71_coxbu(display_long)|uniprotkb:CBU_0077(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286811|imex:IM-26899-499 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000021248(gene)|ensembl:ENSMUST00000040766(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001822"(kidney development)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007030"(Golgi organization)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035964"(COPI-coated vesicle budding)|go:"GO:0042470"(melanosome)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043279"(response to alkaloid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0048199"(vesicle targeting, to, from or within Golgi)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0070765"(gamma-secretase complex)|go:"GO:0106272"(protein localization to ERGIC)|go:"GO:0106273"(cytosol to ERGIC protein transport)|go:"GO:1902003"(regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|mint:Q9D1D4|reactome:R-MMU-204005|reactome:R-MMU-5694530|reactome:R-MMU-6807878|reactome:R-MMU-6811434|go:"GO:0030658"(transport vesicle membrane)|refseq:NP_081051.1 ensemblbacteria:AAO89644(transcript)|ensemblbacteria:CBU_0077(gene)|go:"GO:0016021"(integral component of membrane)|refseq:NP_819130.1|refseq:WP_010957363.1|mint:Q83F71 - comment:mint|function:Involved in vesicular protein trafficking - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:2yUHxM9g4N5wIB8hmL7zQ4BluMc10090 rogid:JKMfHyEgVdel7cHzOgnLRUH7JWo227377 rigid:x/bxJret2G1NP5Pi+LwufSpZCJ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83EM2 uniprotkb:O35680 intact:EBI-21285149|ensemblbacteria:AAO89852 intact:EBI-21286817|ensembl:ENSMUSP00000062066|ensembl:ENSMUSP00000132443 psi-mi:q83em2_coxbu(display_long)|uniprotkb:CBU_0295(locus name) psi-mi:rt12_mouse(display_long)|uniprotkb:Mrps12(gene name)|psi-mi:Mrps12(display_short)|uniprotkb:Rpms12(gene name synonym)|uniprotkb:MT-RPS12(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286839|imex:IM-26899-699 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO89852(transcript)|ensemblbacteria:CBU_0295(gene)|refseq:NP_819338.1|refseq:WP_010957484.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q83EM2 ensembl:ENSMUSG00000045948(gene)|ensembl:ENSMUST00000056078(transcript)|ensembl:ENSMUST00000171183(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR005679(Ribosomal protein S12, bacterial-type)|interpro:IPR006032(Ribosomal protein S12/S23)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:O35680|reactome:R-MMU-5389840|reactome:R-MMU-5419276|go:"GO:0005840"(ribosome)|refseq:NP_036015.1|refseq:XP_006539971.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:93t8PoA8XuYP8WAnEuBgVdP88/U227377 rogid:hIxJajpTu2fEoIYvWeHMn5Xt/4s10090 rigid:PsQqPq2HQKTqFJiv0dXvDxefwyo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83EM2 uniprotkb:Q8BJ37 intact:EBI-21285149|ensemblbacteria:AAO89852 intact:EBI-2943401|uniprotkb:Q8VE39 psi-mi:q83em2_coxbu(display_long)|uniprotkb:CBU_0295(locus name) psi-mi:tydp1_mouse(display_long)|uniprotkb:Tdp1(gene name)|psi-mi:Tdp1(display_short)|uniprotkb:Protein expressed in male leptotene and zygotene spermatocytes 501(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286845|imex:IM-26899-401 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO89852(transcript)|ensemblbacteria:CBU_0295(gene)|refseq:NP_819338.1|refseq:WP_010957484.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q83EM2 go:"GO:0000012"(single strand break repair)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0017005"(3'-tyrosyl-DNA phosphodiesterase activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|reactome:R-MMU-5693571|interpro:IPR010347(Tyrosyl-DNA phosphodiesterase)|mint:Q8BJ37 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:93t8PoA8XuYP8WAnEuBgVdP88/U227377 rogid:QObSHzKmsK/Cq5vkRRtNwqPybgw10090 rigid:I/ciG5gurK0nQOm28ZhuV5lOpIs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DF6 uniprotkb:O35459 intact:EBI-21285191|ensemblbacteria:AAO90316 intact:EBI-646510|uniprotkb:Q5M8P6|ensembl:ENSMUSP00000066092 psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name) psi-mi:ech1_mouse(display_long)|uniprotkb:Ech1(gene name)|psi-mi:Ech1(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286881|imex:IM-26899-503 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90316(transcript)|ensemblbacteria:CBU_0781(gene)|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q83DF6 refseq:NP_058052.1|ensembl:ENSMUSG00000053898(gene)|ensembl:ENSMUST00000066264(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0006635"(fatty acid beta-oxidation)|interpro:IPR001753(Crotonase, core)|interpro:IPR014748(Crontonase, C-terminal)|interpro:IPR018376|interpro:IPR029045|mint:O35459|reactome:R-MMU-9033241|go:"GO:0051750"("delta(3,5)-delta(2,4)-dienoyl-CoA isomerase activity") - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377 rogid:FSiH0dZUTf0WqDSQ8otpzG5WOMY10090 rigid:vQWjlkwxacJUHA3ykV0rm2aHl+A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99MQ4 uniprotkb:Q83DF6 intact:EBI-8412219|intact:MINT-4088506|uniprotkb:Q9D6A2|ensembl:ENSMUSP00000021820|ensembl:ENSMUSP00000136728 intact:EBI-21285191|ensemblbacteria:AAO90316 psi-mi:aspn_mouse(display_long)|uniprotkb:Aspn(gene name)|psi-mi:Aspn(display_short)|uniprotkb:Periodontal ligament-associated protein 1(gene name synonym) psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286875|imex:IM-26899-501 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079987.2|refseq:NP_001165952.1|ensembl:ENSMUSG00000021388(gene)|ensembl:ENSMUST00000021820(transcript)|ensembl:ENSMUST00000177948(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0030282"(bone mineralization)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042995"(cell projection)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070171"(negative regulation of tooth mineralization)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR016352(Small leucine-rich proteoglycan, class I, decorin/asporin/byglycan)|interpro:IPR028548|interpro:IPR032675|mint:Q99MQ4 ensemblbacteria:AAO90316(transcript)|ensemblbacteria:CBU_0781(gene)|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q83DF6 - comment:mint - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:wrlch8StgS/mVuyt7EapTAEeTIo10090 rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377 rigid:zO7ZlNBVYOjEm6lwYUdFjQV0Jj8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DF6 uniprotkb:Q9D115 intact:EBI-21285191|ensemblbacteria:AAO90316 intact:EBI-9989305|ensembl:ENSMUSP00000154190|ensembl:ENSMUSP00000154192|ensembl:ENSMUSP00000154243|ensembl:ENSMUSP00000077996 psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name) psi-mi:zn706_mouse(display_long)|uniprotkb:Znf706(gene name)|psi-mi:Znf706(display_short)|uniprotkb:Zfp706(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286931|imex:IM-26899-271 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90316(transcript)|ensemblbacteria:CBU_0781(gene)|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q83DF6 refseq:NP_080797.1|ensembl:ENSMUSG00000062397(gene)|ensembl:ENSMUST00000078976(transcript)|ensembl:ENSMUST00000226453(transcript)|ensembl:ENSMUST00000226671(transcript)|ensembl:ENSMUST00000228275(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:1902455"(negative regulation of stem cell population maintenance)|interpro:IPR007513(Four F5 protein)|interpro:IPR026939|mint:Q9D115|reactome:R-MMU-212436 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377 rogid:AfBUOZ8pX25JaH2JyvHVCtEf23410090 rigid:QEDN7jbskYt4RQUK7O8h/KykWms false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DF6 uniprotkb:Q80T41 intact:EBI-21285191|ensemblbacteria:AAO90316 intact:EBI-770749|uniprotkb:A2AL05|ensembl:ENSMUSP00000103378 psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name) psi-mi:gabr2_mouse(display_long)|uniprotkb:Gm425(gene name synonym)|uniprotkb:G-protein coupled receptor 51(gene name synonym)|uniprotkb:Gabbr2(gene name)|psi-mi:Gabbr2(display_short)|uniprotkb:Gpr51(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286887|imex:IM-26899-701 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90316(transcript)|ensemblbacteria:CBU_0781(gene)|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q83DF6 refseq:NP_001074610.1|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0004965"(G protein-coupled GABA receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0038039"(G protein-coupled receptor heterodimeric complex)|ensembl:ENSMUSG00000039809(gene)|ensembl:ENSMUST00000107749(transcript)|go:"GO:0043005"(neuron projection)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0150099"(neuron-glial cell signaling)|go:"GO:1902710"(GABA receptor complex)|interpro:IPR000337(GPCR, family 3)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR002455(GPCR, family 3, gamma-aminobutyric acid receptor, type B)|interpro:IPR002457(GPCR, family 3, gamma-aminobutyric acid receptor, type B2)|interpro:IPR017978|interpro:IPR017979|interpro:IPR028082|interpro:IPR041689|mint:Q80T41|reactome:R-MMU-1296041|reactome:R-MMU-418594|reactome:R-MMU-420499|reactome:R-MMU-977444|reactome:R-MMU-997272 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377 rogid:dnGUhfo2YtDMx5QT5gsiVKPUYlw10090 rigid:PNXjDVUY2S7jo3FpLyzlE0NhNxw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O70576 uniprotkb:Q83DF6 intact:EBI-8571608|ensembl:ENSMUSP00000040945|ensembl:ENSMUSP00000125523|intact:UNK-5365402|uniprotkb:B2RSV0 intact:EBI-21285191|ensemblbacteria:AAO90316 psi-mi:stag3_mouse(display_long)|uniprotkb:Stromalin-3(gene name synonym)|uniprotkb:Stag3(gene name)|psi-mi:Stag3(display_short)|uniprotkb:Stromal antigen 3(gene name synonym)|uniprotkb:SCC3 homolog 3(gene name synonym) psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286919|imex:IM-26899-177 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011239250.1|ensembl:ENSMUSG00000036928(gene)|ensembl:ENSMUST00000048028(transcript)|ensembl:ENSMUST00000162245(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0000802"(transverse filament)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007065"(male meiosis sister chromatid cohesion)|go:"GO:0007066"(female meiosis sister chromatid cohesion)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0008278"(cohesin complex)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0034991"(nuclear meiotic cohesin complex)|interpro:IPR013721(STAG)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:O70576|refseq:XP_006504659.1|refseq:NP_058660.2|dip:DIP-60731N ensemblbacteria:AAO90316(transcript)|ensemblbacteria:CBU_0781(gene)|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q83DF6 - function:Meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I|comment:mint - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:VStlV0vm44TtcEnvNQTLPTFy2ok10090 rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377 rigid:xWpizP7PVMRI5naAz7rEOmcn3XI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DF6 uniprotkb:Q9EQG3 intact:EBI-21285191|ensemblbacteria:AAO90316 intact:EBI-21286893|ensembl:ENSMUSP00000093233|uniprotkb:Q9CTT9 psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name) psi-mi:scel_mouse(display_long)|uniprotkb:Scel(gene name)|psi-mi:Scel(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286913|imex:IM-26899-175 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90316(transcript)|ensemblbacteria:CBU_0781(gene)|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q83DF6 go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016020"(membrane)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q9EQG3|ensembl:ENSMUSG00000022123(gene)|ensembl:ENSMUST00000095576(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0008544"(epidermis development)|refseq:NP_075024.2|refseq:XP_006519418.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377 rogid:QuwWPJteTJ5M5sGydZieBCvnNKE10090 rigid:6zWPyGhzCw2NPl2w70e+wq7sJt4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DF6 uniprotkb:P20152 intact:EBI-21285191|ensemblbacteria:AAO90316 intact:EBI-299269|ensembl:ENSMUSP00000028062|uniprotkb:O08704|uniprotkb:Q8CCH1 psi-mi:y781_coxbu(display_long)|uniprotkb:CBU_0781(locus name) psi-mi:vime_mouse(display_long)|uniprotkb:Vim(gene name)|psi-mi:Vim(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286925|imex:IM-26899-703 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90316(transcript)|ensemblbacteria:CBU_0781(gene)|refseq:NP_819802.1|refseq:WP_010957797.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q83DF6 ensembl:ENSMUSG00000026728(gene)|ensembl:ENSMUST00000028062(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1900147"(regulation of Schwann cell migration)|go:"GO:1990254"(keratin filament binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0031252"(cell leading edge)|interpro:IPR027699|interpro:IPR039008|mint:P20152|reactome:R-MMU-264870|reactome:R-MMU-390522|reactome:R-MMU-9013422|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|reactome:R-MMU-9646399|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044297"(cell body)|go:"GO:0045098"(type III intermediate filament)|go:"GO:0045103"(intermediate filament-based process)|refseq:NP_035831.2|dip:DIP-188N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:KG+sZZZpZQBtdFj1uLVuJeaJEvc227377 rogid://GDvGAXOR4hUXNtVpnZefex5v410090 rigid:kZvWEvC2/KZGWn0m1LozPNkLZ+Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q91X17 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-21287144|ensembl:ENSMUSP00000033263|ensembl:ENSMUSP00000146652|uniprotkb:Q3TN64|uniprotkb:Q3TP60|uniprotkb:Q62285 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:urom_mouse(display_long)|uniprotkb:Umod(gene name)|psi-mi:Umod(display_short)|uniprotkb:Tamm-Horsfall urinary glycoprotein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287190|imex:IM-26899-409 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 ensembl:ENSMUSG00000030963(gene)|ensembl:ENSMUST00000033263(transcript)|ensembl:ENSMUST00000209095(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001822"(kidney development)|go:"GO:0002251"(organ or tissue specific immune response)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0003094"(glomerular filtration)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007588"(excretion)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008380"(RNA splicing)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010467"(gene expression)|go:"GO:0015747"(urate transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019864"(IgG binding)|go:"GO:0030104"(water homeostasis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030643"(cellular phosphate ion homeostasis)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035809"(regulation of urine volume)|go:"GO:0042493"|go:"GO:0044861"(protein transport into plasma membrane raft)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046720"(citric acid secretion)|go:"GO:0048871"(multicellular organismal homeostasis)|go:"GO:0048878"(chemical homeostasis)|go:"GO:0050801"(ion homeostasis)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055062"(phosphate ion homeostasis)|go:"GO:0055064"(chloride ion homeostasis)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055078"(sodium ion homeostasis)|go:"GO:0060073"(micturition)|go:"GO:0060170"(ciliary membrane)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070294"(renal sodium ion absorption)|go:"GO:0072044"(collecting duct development)|go:"GO:0072051"(juxtaglomerular apparatus development)|go:"GO:0072070"(loop of Henle development)|go:"GO:0072218"(metanephric ascending thin limb development)|go:"GO:0072221"(metanephric distal convoluted tubule development)|go:"GO:0072233"(metanephric thick ascending limb development)|go:"GO:0072665"(protein localization to vacuole)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097273"(creatinine homeostasis)|go:"GO:0097709"(connective tissue replacement)|go:"GO:0097744"(renal urate salt excretion)|go:"GO:1990266"(neutrophil migration)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001507(Endoglin/CD105 antigen)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR017977|interpro:IPR018097|interpro:IPR024731|interpro:IPR042235|mint:Q91X17|reactome:R-MMU-446203|refseq:NP_001265534.1|refseq:NP_033496.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:6fj7CtmKsz9PbNrghkVxi6E7qL410090 rigid:B1tlywAOdverbDzTaKdZ//o0EJk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DE4 uniprotkb:Q9CZQ9 intact:EBI-21285423|ensemblbacteria:AAO90328 intact:EBI-6127679|uniprotkb:A2AUC7|ensembl:ENSMUSP00000074494 psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name) psi-mi:bbs5_mouse(display_long)|uniprotkb:Bbs5(gene name)|psi-mi:Bbs5(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286937|imex:IM-26899-601 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90328(transcript)|ensemblbacteria:CBU_0794(gene)|refseq:NP_819814.1|refseq:WP_010957806.1|mint:Q83DE4 refseq:NP_082560.1|ensembl:ENSMUSG00000063145(gene)|ensembl:ENSMUST00000074963(transcript)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0015031"(protein transport)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034464"(BBSome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0046907"(intracellular transport)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR006606(Protein of unknown function DUF1448)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014003(Protein of unknown function DM16)|interpro:IPR030804|mint:Q9CZQ9|reactome:R-MMU-5620922 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:XVA7R483yYdpYkhCnAqOzU8u000227377 rogid:tpfXPd3gpQIC6+kp3OOpwiXrZe810090 rigid:NDO2dKTievhPk0qo0SC1RqxyqOA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q80ZX0 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-21287002|ensembl:ENSMUSP00000001079 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:q80zx0_mouse(display_long)|uniprotkb:Sec24b(gene name)|psi-mi:Sec24b(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287132|imex:IM-26899-179 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 ensembl:ENSMUSG00000001052(gene)|ensembl:ENSMUST00000001079(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0002093"(auditory receptor cell morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060463"(lung lobe morphogenesis)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:0061156"(pulmonary artery morphogenesis)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0072359"(circulatory system development)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0090178"(regulation of establishment of planar polarity involved in neural tube closure)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|mint:Q80ZX0|reactome:R-MMU-204005|reactome:R-MMU-2132295|reactome:R-MMU-5694530|reactome:R-MMU-983170|go:"GO:1901301"(regulation of cargo loading into COPII-coated vesicle)|refseq:NP_997092.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:+zaf3WMuqlsjaY+q3lVV5IXuMK010090 rigid:oeCGVci9WtUNLIj1KyDXS9i9QCo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q80TF4 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-9673336|uniprotkb:A2AL86|uniprotkb:A2AL87|uniprotkb:A2AL88|uniprotkb:A2AL89|uniprotkb:Q9DBY7|ensembl:ENSMUSP00000110972 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:klh13_mouse(display_long)|uniprotkb:Klhl13(gene name)|psi-mi:Klhl13(display_short)|uniprotkb:Bklhd2(gene name synonym)|uniprotkb:Kiaa1309(gene name synonym)|uniprotkb:BTB and kelch domain-containing protein 2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287126|imex:IM-26899-707 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_001297395.1|refseq:XP_011245791.1|refseq:XP_011245794.1|refseq:XP_011245795.1|refseq:XP_011245796.1|refseq:XP_017174099.1|refseq:NP_001277405.1|refseq:NP_080443.1|ensembl:ENSMUSG00000036782(gene)|ensembl:ENSMUST00000115317(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0007049"(cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030496"(midbody)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051301"(cell division)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|mint:Q80TF4|reactome:R-MMU-8951664|reactome:R-MMU-983168 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:toLcULHqvUiIszWbXJHgVMsXTEg10090 rigid:K677ry9LsSnmIhaVTkVyWvqoMPE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q00612 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-647776|ensembl:ENSMUSP00000004327 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:g6pd1_mouse(display_long)|uniprotkb:G6pdx(gene name)|psi-mi:G6pdx(display_short)|uniprotkb:G6pd(gene name synonym)|uniprotkb:G6pd-1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287120|imex:IM-26899-405 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_032088.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006739"(NADP metabolic process)|go:"GO:0006740"(NADPH regeneration)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009051"(pentose-phosphate shunt, oxidative branch)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010734"(negative regulation of protein glutathionylation)|go:"GO:0019322"(pentose biosynthetic process)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0046390"(ribose phosphate biosynthetic process)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050661"(NADP binding)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|go:"GO:0005634"(nucleus)|ensembl:ENSMUSG00000031400(gene)|ensembl:ENSMUST00000004327(transcript)|go:"GO:0001998"(angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure)|go:"GO:0002033"(angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure)|go:"GO:0004345"(glucose-6-phosphate dehydrogenase activity)|go:"GO:0005536"(glucose binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001282(Glucose-6-phosphate dehydrogenase)|interpro:IPR019796|interpro:IPR022674|interpro:IPR022675|interpro:IPR036291|mint:Q00612|reactome:R-MMU-5628897|reactome:R-MMU-71336|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development) - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:2CPZ84pzjTPslBJfopjgJR5+fyw10090 rigid:V+pJR8gkwAO2OHOHem38D5t3jfQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q7TMV3 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-21287094|ensembl:ENSMUSP00000105891|uniprotkb:Q3UNY5|uniprotkb:Q5DTV0 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:fakd5_mouse(display_long)|uniprotkb:Fastkd5(gene name)|psi-mi:Fastkd5(display_short)|uniprotkb:Kiaa1792(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287114|imex:IM-26899-513 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 go:"GO:0044528"(regulation of mitochondrial mRNA stability)|interpro:IPR010622(FAST kinase leucine-rich)|interpro:IPR013579(FAST kinase-like protein, subdomain 2)|interpro:IPR013584(RAP domain)|mint:Q7TMV3|go:"GO:0042645"(mitochondrial nucleoid)|ensembl:ENSMUSG00000079043(gene)|ensembl:ENSMUST00000110262(transcript)|go:"GO:0000963"(mitochondrial RNA processing)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0019843"(rRNA binding)|go:"GO:0035770"(ribonucleoprotein granule)|refseq:NP_001139556.1|refseq:NP_937819.2 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:cOiP55i6r48Z2npDUTZMQrUt/pc10090 rigid:sImfNtB381Dg5F6vE9EmotnFbpY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q9D518 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-11568244|uniprotkb:A2AR82|ensembl:ENSMUSP00000106076|ensembl:ENSMUSP00000136349 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:f227b_mouse(display_long)|uniprotkb:Fam227b(gene name)|psi-mi:Fam227b(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287088|imex:IM-26899-273 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_083731.2|ensembl:ENSMUSG00000027209(gene)|ensembl:ENSMUST00000110446(transcript)|ensembl:ENSMUST00000178118(transcript)|interpro:IPR029417|mint:Q9D518 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:blnIazwCtDkSf2WzxULzu27j4ik10090 rigid:6AbNT1dp6U7SN6h9Z/mWRdC/2T8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q8CGC7 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-4285489|uniprotkb:Q3UFJ2|uniprotkb:Q4VC16|uniprotkb:E9QKC4|ensembl:ENSMUSP00000045841 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:syep_mouse(display_long)|uniprotkb:Eprs(gene name synonym)|uniprotkb:Qprs(gene name synonym)|uniprotkb:Eprs1(gene name)|psi-mi:Eprs1(display_short)|uniprotkb:Bifunctional aminoacyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287082|imex:IM-26899-605 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_084011.1|ensembl:ENSMUSG00000026615(gene)|ensembl:ENSMUST00000046514(transcript)|go:"GO:0004818"(glutamate-tRNA ligase activity)|go:"GO:0004827"(proline-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006424"(glutamyl-tRNA aminoacylation)|go:"GO:0006433"(prolyl-tRNA aminoacylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051020"(GTPase binding)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:0140212"(regulation of long-chain fatty acid import into cell)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000738(WHEP-TRS)|interpro:IPR000924(Glutamyl/glutaminyl-tRNA synthetase, class Ic)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR004154(Anticodon-binding)|interpro:IPR004499(Prolyl-tRNA synthetase, class IIa, prokaryotic-type)|interpro:IPR004526(Glutamyl-tRNA synthetase, class Ic, archaeal/eukaryotic cytosolic)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR011035(Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR016061(Prolyl-tRNA synthetase, class II, C-terminal)|interpro:IPR017449(Prolyl-tRNA synthetase, class II)|interpro:IPR020056|interpro:IPR020058|interpro:IPR020059|interpro:IPR033721|interpro:IPR036282|interpro:IPR036621|mint:Q8CGC7|interpro:IPR004046(Glutathione S-transferase, C-terminal) - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:uFcCD59N912Lvyf6/OxGsROezcU10090 rigid:pRD9qXUBa+TGW1PrsTKlxIyBtlk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34914 uniprotkb:Q83D60 intact:EBI-8321134|intact:MINT-1859181|uniprotkb:Q8CGV0|ensembl:ENSMUSP00000069209 intact:EBI-21285556|ensemblbacteria:AAO90413 psi-mi:hyes_mouse(display_long)|uniprotkb:Ephx2(gene name)|psi-mi:Ephx2(display_short)|uniprotkb:Eph2(gene name synonym) psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287076|imex:IM-26899-603 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001258332.1|refseq:NP_031966.2|ensembl:ENSMUSG00000022040(gene)|ensembl:ENSMUST00000070515(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002539"(prostaglandin production involved in inflammatory response)|go:"GO:0004301"(epoxide hydrolase activity)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0033885"("10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity")|go:"GO:0042577"(lipid phosphatase activity)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043651"(linoleic acid metabolic process)|go:"GO:0045777"(positive regulation of blood pressure)|go:"GO:0046272"(stilbene catabolic process)|go:"GO:0046839"(phospholipid dephosphorylation)|go:"GO:0052642"(lysophosphatidic acid phosphatase activity)|go:"GO:0090181"(regulation of cholesterol metabolic process)|go:"GO:0097176"(epoxide metabolic process)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000639(Epoxide hydrolase-like)|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|interpro:IPR023214|interpro:IPR029058|interpro:IPR036412|interpro:IPR041492|mint:P34914|rcsb pdb:1CQZ|rcsb pdb:1CR6|rcsb pdb:1EK1|rcsb pdb:1EK2|reactome:R-MMU-2142670|reactome:R-MMU-9018682|reactome:R-MMU-9033241 ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 - function:"Acts on epoxides (alkene oxides, oxiranes) and arene oxides. Plays a role in xenobiotic metabolism by degrading potentially toxic epoxides. Also determines steady-state levels of physiological mediators. Has phosphatase activity"|comment:mint - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:jK9/K11NHaeX7vX0aK77T/hbYlU10090 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rigid:iNxhAMWbYHS1iwauMSxMhMib7jw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3TDX8 uniprotkb:Q83D60 intact:EBI-7928047|uniprotkb:Q6VXY4|uniprotkb:Q8BTI5|uniprotkb:Q3U012|uniprotkb:Q8BJV8|intact:UNK-5537179|uniprotkb:Q3TJH3|uniprotkb:Q6VXY5|uniprotkb:E9Q129|uniprotkb:Q8R3H8|uniprotkb:Q99LY4|uniprotkb:Q99P29|ensembl:ENSMUSP00000126119 intact:EBI-21285556|ensemblbacteria:AAO90413 psi-mi:nb5r4_mouse(display_long)|uniprotkb:Cyb5r4(gene name)|psi-mi:Cyb5r4(display_short)|uniprotkb:Ncb5or(gene name synonym)|uniprotkb:Flavohemoprotein b5/b5R(gene name synonym)|uniprotkb:cb5/cb5R(gene name synonym)|uniprotkb:N-terminal cytochrome b5 and cytochrome b5 oxidoreductase domain-containing protein(gene name synonym) psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287070|imex:IM-26899-511 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077157.2|refseq:XP_006511262.1|ensembl:ENSMUSG00000032872(gene)|ensembl:ENSMUST00000168529(transcript)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0004128"("cytochrome-b5 reductase activity, acting on NAD(P)H")|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006739"(NADP metabolic process)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016653"("oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor")|go:"GO:0020037"(heme binding)|interpro:IPR001199(Cytochrome b5)|go:"GO:0030073"(insulin secretion)|go:"GO:0042168"(heme metabolic process)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0046677"(response to antibiotic)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001834("NADH:cytochrome b5 reductase (CBR)")|interpro:IPR007052(CS domain)|interpro:IPR008333(Oxidoreductase FAD-binding region)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR017927|interpro:IPR017938|interpro:IPR018506|interpro:IPR036400|interpro:IPR037908|interpro:IPR039261|mint:Q3TDX8|reactome:R-MMU-1237044|go:"GO:0046872"(metal ion binding)|go:"GO:0048468"(cell development)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0072593"(reactive oxygen species metabolic process) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 - comment:mint|function:"NADH-cytochrome b5 reductase involved in endolasmic reticulum stress response pathway. Plays a critical role in protecting pancreatic beta-cells against oxidant stress, possibly by protecting the cell from excess buildup of reactive oxygen species (ROS)" - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:j19wK584v3ZVxPwALGRiJ1DnnvU10090 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rigid:cqEqExFKNPctVrTHc/4UHAbQGVk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q9CZQ9 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-6127679|uniprotkb:A2AUC7|ensembl:ENSMUSP00000074494 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:bbs5_mouse(display_long)|uniprotkb:Bbs5(gene name)|psi-mi:Bbs5(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287064|imex:IM-26899-63 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_082560.1|ensembl:ENSMUSG00000063145(gene)|ensembl:ENSMUST00000074963(transcript)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0015031"(protein transport)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034464"(BBSome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0046907"(intracellular transport)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR006606(Protein of unknown function DUF1448)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014003(Protein of unknown function DM16)|interpro:IPR030804|mint:Q9CZQ9|reactome:R-MMU-5620922 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:tpfXPd3gpQIC6+kp3OOpwiXrZe810090 rigid:dyt6D/sUyJESdvEbY7++GXG6kyE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D593 uniprotkb:Q83D60 intact:EBI-8315471|ensembl:ENSMUSP00000065285|ensembl:ENSMUSP00000157068|ensembl:ENSMUSP00000157221|intact:MINT-4127094|uniprotkb:Q6P8U8|uniprotkb:Q810S5 intact:EBI-21285556|ensemblbacteria:AAO90413 psi-mi:vate2_mouse(display_long)|uniprotkb:Atp6v1e2(gene name)|psi-mi:Atp6v1e2(display_short)|uniprotkb:Atp6e1(gene name synonym)|uniprotkb:Vacuolar proton pump subunit E 2(gene name synonym) psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287058|imex:IM-26899-705 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000053375(gene)|ensembl:ENSMUST00000065758(transcript)|ensembl:ENSMUST00000233995(transcript)|ensembl:ENSMUST00000235110(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0033178"(proton-transporting two-sector ATPase complex, catalytic domain)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002842(ATPase, V1/A1 complex, subunit E)|interpro:IPR038495|mint:Q9D593|reactome:R-MMU-1222556|reactome:R-MMU-77387|reactome:R-MMU-917977|reactome:R-MMU-9639288|reactome:R-MMU-983712|refseq:NP_083397.3 ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 - comment:mint|function:Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. This isoform is essential for energy coupling involved in acidification of acrosome - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:kefmVCpqrIIVY4FNWvd17Yz3DR410090 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rigid:oQhxVqU7X81s/ViwWFf49IPgwT8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q8C0M9 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-2308217|uniprotkb:Q91WC8|uniprotkb:Q9CVX3|ensembl:ENSMUSP00000051709 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:asgl1_mouse(display_long)|uniprotkb:Beta-aspartyl-peptidase(gene name synonym)|uniprotkb:Isoaspartyl dipeptidase(gene name synonym)|uniprotkb:Asrgl1(gene name)|psi-mi:Asrgl1(display_short)|uniprotkb:L-asparagine amidohydrolase(gene name synonym)|uniprotkb:Asparaginase-like protein 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287052|imex:IM-26899-509 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_079886.2|ensembl:ENSMUSG00000024654(gene)|ensembl:ENSMUST00000049948(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0004067"(asparaginase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0008798"(beta-aspartyl-peptidase activity)|go:"GO:0033345"(asparagine catabolic process via L-aspartate)|interpro:IPR000246(Peptidase T2, asparaginase 2)|interpro:IPR029055|interpro:IPR033844|mint:Q8C0M9|reactome:R-MMU-8964208 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:wiexavwMdQbxSvFKT3feeH1J0+010090 rigid:ccP0Wk81nw4zSij2GuB6nL+n0nU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DE4 uniprotkb:Q80ZX0 intact:EBI-21285423|ensemblbacteria:AAO90328 intact:EBI-21287002|ensembl:ENSMUSP00000001079 psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name) psi-mi:q80zx0_mouse(display_long)|uniprotkb:Sec24b(gene name)|psi-mi:Sec24b(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287046|imex:IM-26899-507 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90328(transcript)|ensemblbacteria:CBU_0794(gene)|refseq:NP_819814.1|refseq:WP_010957806.1|mint:Q83DE4 ensembl:ENSMUSG00000001052(gene)|ensembl:ENSMUST00000001079(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0002093"(auditory receptor cell morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060463"(lung lobe morphogenesis)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:0061156"(pulmonary artery morphogenesis)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0072359"(circulatory system development)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0090178"(regulation of establishment of planar polarity involved in neural tube closure)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|mint:Q80ZX0|reactome:R-MMU-204005|reactome:R-MMU-2132295|reactome:R-MMU-5694530|reactome:R-MMU-983170|go:"GO:1901301"(regulation of cargo loading into COPII-coated vesicle)|refseq:NP_997092.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:XVA7R483yYdpYkhCnAqOzU8u000227377 rogid:+zaf3WMuqlsjaY+q3lVV5IXuMK010090 rigid:xSBvXVp5Dz44msjkAaz9Jx8WpdE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DE4 uniprotkb:P47867 intact:EBI-21285423|ensemblbacteria:AAO90328 intact:EBI-21286974|ensembl:ENSMUSP00000034699|uniprotkb:Q3UTT1|uniprotkb:Q3UZT8|uniprotkb:Q8R1D7 psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name) psi-mi:scg3_mouse(display_long)|uniprotkb:Scg3(gene name)|psi-mi:Scg3(display_short)|uniprotkb:Secretogranin III(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286996|imex:IM-26899-793 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90328(transcript)|ensemblbacteria:CBU_0794(gene)|refseq:NP_819814.1|refseq:WP_010957806.1|mint:Q83DE4 ensembl:ENSMUSG00000032181(gene)|ensembl:ENSMUST00000034699(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0033366"(protein localization to secretory granule)|interpro:IPR026197|mint:P47867|reactome:R-MMU-114608|reactome:R-MMU-381426|reactome:R-MMU-8957275|refseq:NP_001158262.1|refseq:NP_033156.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:XVA7R483yYdpYkhCnAqOzU8u000227377 rogid:ia7SjSo9AAmvuZ4UgzR0z7G0wSo10090 rigid:juM+aIdwrRd8+yO2loXSbPfsyTs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DE4 uniprotkb:Q9CQK3 intact:EBI-21285423|ensemblbacteria:AAO90328 intact:EBI-21286949|ensembl:ENSMUSP00000010506 psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name) psi-mi:rdm1_mouse(display_long)|uniprotkb:Rdm1(gene name)|psi-mi:Rdm1(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286968|imex:IM-26899-403 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90328(transcript)|ensemblbacteria:CBU_0794(gene)|refseq:NP_819814.1|refseq:WP_010957806.1|mint:Q83DE4 go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016605"(PML body)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034200|interpro:IPR035979|interpro:IPR040224|mint:Q9CQK3|ensembl:ENSMUSG00000010362(gene)|ensembl:ENSMUST00000010506(transcript)|go:"GO:0003677"(DNA binding)|refseq:NP_079930.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:XVA7R483yYdpYkhCnAqOzU8u000227377 rogid:WYhFLJYXhm6rBwqMY5L004/llp410090 rigid:C/lHRn/OCIdxfW/iLgyc8hxPYZc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DE4 uniprotkb:O08529 intact:EBI-21285423|ensemblbacteria:AAO90328 intact:EBI-643151|uniprotkb:O35518|uniprotkb:O54843|ensembl:ENSMUSP00000068895 psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name) psi-mi:can2_mouse(display_long)|uniprotkb:Calpain-2 large subunit(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase 2(gene name synonym)|uniprotkb:Calpain M-type(gene name synonym)|uniprotkb:Millimolar-calpain(gene name synonym)|uniprotkb:80 kDa M-calpain subunit(gene name synonym)|uniprotkb:Capn2(gene name)|psi-mi:Capn2(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21286943|imex:IM-26899-505 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90328(transcript)|ensemblbacteria:CBU_0794(gene)|refseq:NP_819814.1|refseq:WP_010957806.1|mint:Q83DE4 refseq:NP_033924.2|interpro:IPR002048(Calcium-binding EF-hand)|ensembl:ENSMUSG00000026509(gene)|ensembl:ENSMUST00000068505(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006508"(proteolysis)|go:"GO:0007520"(myoblast fusion)|go:"GO:0007565"(female pregnancy)|go:"GO:0000785"(chromatin)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001824"(blastocyst development)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0031143"(pseudopodium)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0005509"(calcium ion binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:2001247"(positive regulation of phosphatidylcholine biosynthetic process)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR001300(Peptidase C2, calpain)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022682|interpro:IPR022683|interpro:IPR022684|interpro:IPR029539|interpro:IPR033883|interpro:IPR036213|interpro:IPR038765|interpro:IPR042736|mint:O08529|reactome:R-MMU-1474228 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:XVA7R483yYdpYkhCnAqOzU8u000227377 rogid:1AC+IJ8bHwaYB7bBlMFxmV8PNss10090 rigid:CM41orM9AhRUPlzR9aWsy6NBM+Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:P70663 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-2012890|uniprotkb:E9QPH2|uniprotkb:P97810|uniprotkb:Q99L82|ensembl:ENSMUSP00000031249 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:sprl1_mouse(display_long)|uniprotkb:Sparcl1(gene name)|psi-mi:Sparcl1(display_short)|uniprotkb:Ecm2(gene name synonym)|uniprotkb:Sc1(gene name synonym)|uniprotkb:Matrix glycoprotein Sc1(gene name synonym)|uniprotkb:Extracellular matrix protein 2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287138|imex:IM-26899-407 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_034227.3|refseq:XP_017176145.1|refseq:XP_006534831.1|ensembl:ENSMUSG00000029309(gene)|ensembl:ENSMUST00000031249(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0007165"(signal transduction)|go:"GO:0045202"(synapse)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0098965"(extracellular matrix of synaptic cleft)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099560"(synaptic membrane adhesion)|interpro:IPR001999(Osteonectin-like, conserved site)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR003645(Follistatin-like, N-terminal)|interpro:IPR011992(EF-Hand type)|interpro:IPR015369(Follistatin)|interpro:IPR016359(SPARC-like protein 1)|interpro:IPR018247|interpro:IPR019577|interpro:IPR036058|mint:P70663|reactome:R-MMU-381426|reactome:R-MMU-8957275 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:PdnEQBF1vQqXJM9/Qiz/45+Mdc410090 rigid:N0+kobeeS3CUhluD20EWW7Y0FJU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83BP6 uniprotkb:Q9QZV9 intact:EBI-21286233|ensemblbacteria:AAO90954 intact:EBI-444161|ensembl:ENSMUSP00000038329|ensembl:ENSMUSP00000105587|uniprotkb:Q3THE3|uniprotkb:Q9D1P7 psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name) psi-mi:nxt1_mouse(display_long)|uniprotkb:Nxt1(gene name)|psi-mi:Nxt1(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287293|imex:IM-26899-71 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90954(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|ensemblbacteria:CBU_1457(gene)|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q83BP6 ensembl:ENSMUSG00000036992(gene)|ensembl:ENSMUST00000047177(transcript)|ensembl:ENSMUST00000109961(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0031267"(small GTPase binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR018222|mint:Q9QZV9|reactome:R-MMU-159236|interpro:IPR032710|refseq:NP_001103629.1|refseq:NP_062735.4 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:mIymO86AHiWEAXMs6/mzjWip6QU227377 rogid:UYRPbn587LwVg2BN44nZaFdCg/A10090 rigid:eeT7IFdBSwrunxQFWQ4Hm20EZMc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9CQ48 uniprotkb:Q83BP6 intact:EBI-8586360|ensembl:ENSMUSP00000020578|uniprotkb:Q8CD03|intact:UNK-5539816|uniprotkb:Q9D0V4|uniprotkb:Q9CY63 intact:EBI-21286233|ensemblbacteria:AAO90954 psi-mi:nudc2_mouse(display_long)|uniprotkb:Nudcd2(gene name)|psi-mi:Nudcd2(display_short)|uniprotkb:D11Ertd603e(gene name synonym) psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287287|imex:IM-26899-69 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020328(gene)|ensembl:ENSMUST00000020578(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0072686"(mitotic spindle)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037898|interpro:IPR037902|mint:Q9CQ48|rcsb pdb:2RH0|refseq:NP_080299.4|refseq:NP_001277626.1 ensemblbacteria:AAO90954(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|ensemblbacteria:CBU_1457(gene)|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q83BP6 - comment:mint - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:jBd4WysI/l/Xz5ClWNIiY2zcQ5Y10090 rogid:mIymO86AHiWEAXMs6/mzjWip6QU227377 rigid:d3IVrswRcB5N8DfCDaqOgOkL71Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83BP6 uniprotkb:Q3KNJ2 intact:EBI-21286233|ensemblbacteria:AAO90954 intact:EBI-21287262|ensembl:ENSMUSP00000116797|uniprotkb:A2RT39|uniprotkb:Q99JK0|uniprotkb:Q9D9U0 psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name) psi-mi:nhej1_mouse(display_long)|uniprotkb:Nhej1(gene name)|psi-mi:Nhej1(display_short)|uniprotkb:Xlf(gene name synonym)|uniprotkb:Protein cernunnos(gene name synonym)|uniprotkb:XRCC4-like factor(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287281|imex:IM-26899-609 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90954(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|ensemblbacteria:CBU_1457(gene)|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q83BP6 go:"GO:0032807"(DNA ligase IV complex)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0035861"(site of double-strand break)|go:"GO:0045027"(DNA end binding)|go:"GO:0051103"(DNA ligation involved in DNA repair)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070419"(nonhomologous end joining complex)|interpro:IPR015381(XLF/Cernunnos)|interpro:IPR038051|mint:Q3KNJ2|reactome:R-MMU-5693571|ensembl:ENSMUSG00000026162(gene)|ensembl:ENSMUST00000152855(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|refseq:NP_083618.3 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:mIymO86AHiWEAXMs6/mzjWip6QU227377 rogid:CaCAVXisLOoa0sadZ/KQ3spZDRs10090 rigid:G/UqNlWW4+yooaV48sLmkR9C+Ks false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83BP6 uniprotkb:P20029 intact:EBI-21286233|ensemblbacteria:AAO90954 intact:EBI-772325|uniprotkb:Q3UFF2|uniprotkb:O35642|uniprotkb:Q61630|intact:EBI-4280750|ensembl:ENSMUSP00000028222|ensembl:ENSMUSP00000097747 psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name) psi-mi:bip_mouse(display_long)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:Hspa5(gene name)|psi-mi:Hspa5(display_short)|uniprotkb:Grp78(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287256|imex:IM-26899-795 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90954(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|ensemblbacteria:CBU_1457(gene)|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q83BP6 refseq:NP_001156906.1|refseq:NP_071705.3|dip:DIP-32341N|ensembl:ENSMUSG00000026864(gene)|ensembl:ENSMUST00000028222(transcript)|ensembl:ENSMUST00000100171(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006983"(ER overload response)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P20029|reactome:R-MMU-3371453|reactome:R-MMU-983170 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:mIymO86AHiWEAXMs6/mzjWip6QU227377 rogid:AyJwwnH8IAQqF/cbTn336A79MOY10090 rigid:TdEaOR7u0MOuhiHjCaMJIEvq5w4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83BP6 uniprotkb:Q8BUV3 intact:EBI-21286233|ensemblbacteria:AAO90954 intact:EBI-771218|uniprotkb:E9QKJ1|ensembl:ENSMUSP00000054064 psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name) psi-mi:geph_mouse(display_long)|uniprotkb:Gphn(gene name)|psi-mi:Gphn(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287250|imex:IM-26899-709 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90954(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|ensemblbacteria:CBU_1457(gene)|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q83BP6 refseq:NP_766540.2|ensembl:ENSMUSG00000047454(gene)|ensembl:ENSMUST00000052472(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006777"(Mo-molybdopterin cofactor biosynthetic process)|go:"GO:0007529"(establishment of synaptic specificity at neuromuscular junction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008940"(nitrate reductase activity)|go:"GO:0010038"(response to metal ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0018315"(molybdenum incorporation into molybdenum-molybdopterin complex)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032324"(molybdopterin cofactor biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043546"(molybdopterin cofactor binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061598"(molybdopterin adenylyltransferase activity)|go:"GO:0061599"(molybdopterin molybdotransferase activity)|go:"GO:0072579"(glycine receptor clustering)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097112"(gamma-aminobutyric acid receptor clustering)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098879"(structural constituent of postsynaptic specialization)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099091"(postsynaptic specialization, intracellular component)|go:"GO:0099144"(anchored component of synaptic membrane)|go:"GO:0099572"(postsynaptic specialization)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|interpro:IPR001453(Molybdopterin binding)|interpro:IPR005110(MoeA, N-terminal, domain I and II)|interpro:IPR005111(MoeA, C-terminal, domain IV)|interpro:IPR008284(Molybdenum cofactor biosynthesis, conserved site)|interpro:IPR036135|interpro:IPR036425|interpro:IPR036688|interpro:IPR038987|mint:Q8BUV3|reactome:R-MMU-947581 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:mIymO86AHiWEAXMs6/mzjWip6QU227377 rogid:lOuhzjy/8/eDNnV08I0WbLvRiiA10090 rigid:Q6GswgwxctH9ZTnvaUeFAjfSVyU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83BP6 uniprotkb:F8VQ05 intact:EBI-21286233|ensemblbacteria:AAO90954 intact:EBI-16370307|ensembl:ENSMUSP00000092289|ensembl:ENSMUSP00000098687 psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name) psi-mi:f8vq05_mouse(display_long)|uniprotkb:Fryl(gene name)|psi-mi:Fryl(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287244|imex:IM-26899-67 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90954(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|ensemblbacteria:CBU_1457(gene)|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q83BP6 go:"GO:0005938"(cell cortex)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031175"(neuron projection development)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025481|interpro:IPR025614|interpro:IPR029473|interpro:IPR039867|mint:F8VQ05|ensembl:ENSMUSG00000070733(gene)|ensembl:ENSMUST00000094700(transcript)|ensembl:ENSMUST00000101127(transcript)|go:"GO:0000902"(cell morphogenesis)|refseq:NP_082470.2 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:mIymO86AHiWEAXMs6/mzjWip6QU227377 rogid:z7d54gf0a+ZldqO/5HVNPkwN+nY10090 rigid:+2H2FA3/D85+lq2jjiNEBnTfKfM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83BP6 uniprotkb:P26883 intact:EBI-21286233|ensemblbacteria:AAO90954 intact:EBI-6379901|ensembl:ENSMUSP00000037206|uniprotkb:Q545E9 psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name) psi-mi:fkb1a_mouse(display_long)|uniprotkb:Fkbp1a(gene name)|psi-mi:Fkbp1a(display_short)|uniprotkb:Fkbp1(gene name synonym)|uniprotkb:12 kDa FK506-binding protein(gene name synonym)|uniprotkb:Calstabin-1(gene name synonym)|uniprotkb:FK506-binding protein 1A(gene name synonym)|uniprotkb:Immunophilin FKBP12(gene name synonym)|uniprotkb:Rotamase(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287238|imex:IM-26899-279 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90954(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|ensemblbacteria:CBU_1457(gene)|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q83BP6 go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032925"(regulation of activin receptor signaling pathway)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043679"(axon terminus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0046332"(SMAD binding)|go:"GO:0048185"(activin binding)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990425"(ryanodine receptor complex)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|mint:P26883|reactome:R-MMU-166208|reactome:R-MMU-2025928|reactome:R-MMU-2173789|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031312"(extrinsic component of organelle membrane)|go:"GO:0031398"(positive regulation of protein ubiquitination)|ensembl:ENSMUSG00000032966(gene)|ensembl:ENSMUST00000044011(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005528"(FK506 binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0016020"(membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|refseq:NP_001289006.1|refseq:NP_001289007.1|refseq:NP_001289008.1|refseq:NP_001289009.1|dip:DIP-29707N|refseq:NP_032045.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:mIymO86AHiWEAXMs6/mzjWip6QU227377 rogid:G3Dq41lUNMncyt6e7S8Ntwy5K3Y10090 rigid:g00AJCJf3zVRARR0HQbfbvfOqdY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83BP6 uniprotkb:Q9WUB4 intact:EBI-21286233|ensemblbacteria:AAO90954 intact:EBI-9988920|uniprotkb:Q8C2M9|uniprotkb:Q9QZB8|ensembl:ENSMUSP00000033913 psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name) psi-mi:dctn6_mouse(display_long)|uniprotkb:Dctn6(gene name)|psi-mi:Dctn6(display_short)|uniprotkb:Ws3(gene name synonym)|uniprotkb:Dynactin subunit p27(gene name synonym)|uniprotkb:Protein WS-3(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287232|imex:IM-26899-277 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90954(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|ensemblbacteria:CBU_1457(gene)|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q83BP6 refseq:NP_001280686.1|refseq:NP_001280687.1|refseq:NP_001280688.1|refseq:NP_035852.1|ensembl:ENSMUSG00000031516(gene)|ensembl:ENSMUST00000033913(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003824"(catalytic activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005869"(dynactin complex)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0070840"(dynein complex binding)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR027777|mint:Q9WUB4|reactome:R-MMU-2132295|reactome:R-MMU-3371497|reactome:R-MMU-6807878|reactome:R-MMU-6811436 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:mIymO86AHiWEAXMs6/mzjWip6QU227377 rogid:Dd+/GShX4ejVZ07DseNGbUUyJYg10090 rigid:RB7C0lFGguN7rx046+2/9IcDpF8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83BP6 uniprotkb:Q9WTX6 intact:EBI-21286233|ensemblbacteria:AAO90954 intact:EBI-1551052|uniprotkb:Q9WUI7|ensembl:ENSMUSP00000031697 psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name) psi-mi:cul1_mouse(display_long)|uniprotkb:Cul1(gene name)|psi-mi:Cul1(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287226|imex:IM-26899-181 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90954(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|ensemblbacteria:CBU_1457(gene)|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q83BP6 refseq:XP_006506251.1|refseq:XP_006506252.1|refseq:NP_036172.1|refseq:XP_006506253.1|dip:DIP-39799N|ensembl:ENSMUSG00000029686(gene)|ensembl:ENSMUST00000031697(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q9WTX6|reactome:R-MMU-1169091|reactome:R-MMU-1170546|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2565942|reactome:R-MMU-2871837|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5676590|reactome:R-MMU-5684264|reactome:R-MMU-68949|reactome:R-MMU-69231|reactome:R-MMU-8854050|reactome:R-MMU-8939902|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-917937|reactome:R-MMU-9708530|reactome:R-MMU-983168 - - crc64:3E1F8B63C6E498F4 figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:mIymO86AHiWEAXMs6/mzjWip6QU227377 rogid:PvC7VcW1uCGZ/O7NUERQocqZdok10090 rigid:BPzU2pU8FpCw919W5elmOxmmN6w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83BP6 uniprotkb:P22518 intact:EBI-21286233|ensemblbacteria:AAO90954 intact:EBI-6479117|uniprotkb:A6H6K2|uniprotkb:Q3UXB6|ensembl:ENSMUSP00000034868 psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name) psi-mi:clk1_mouse(display_long)|uniprotkb:Clk1(gene name)|psi-mi:Clk1(display_short)|uniprotkb:Clk(gene name synonym)|uniprotkb:Sty(gene name synonym)|uniprotkb:CDC-like kinase 1(gene name synonym)|uniprotkb:Protein kinase STY(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287220|imex:IM-26899-515 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90954(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|ensemblbacteria:CBU_1457(gene)|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q83BP6 refseq:NP_001036099.1|ensembl:ENSMUSG00000026034(gene)|ensembl:ENSMUST00000034868(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P22518 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:mIymO86AHiWEAXMs6/mzjWip6QU227377 rogid:X8WBFAKvewkpwRj6GMc55rqWUzs10090 rigid:HOjpFpr4x8jTxI7xAogDAo8iBsQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83BP6 uniprotkb:Q8C0M9 intact:EBI-21286233|ensemblbacteria:AAO90954 intact:EBI-2308217|uniprotkb:Q91WC8|uniprotkb:Q9CVX3|ensembl:ENSMUSP00000051709 psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name) psi-mi:asgl1_mouse(display_long)|uniprotkb:Beta-aspartyl-peptidase(gene name synonym)|uniprotkb:Isoaspartyl dipeptidase(gene name synonym)|uniprotkb:Asrgl1(gene name)|psi-mi:Asrgl1(display_short)|uniprotkb:L-asparagine amidohydrolase(gene name synonym)|uniprotkb:Asparaginase-like protein 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287214|imex:IM-26899-65 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90954(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|ensemblbacteria:CBU_1457(gene)|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q83BP6 refseq:NP_079886.2|ensembl:ENSMUSG00000024654(gene)|ensembl:ENSMUST00000049948(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0004067"(asparaginase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0008798"(beta-aspartyl-peptidase activity)|go:"GO:0033345"(asparagine catabolic process via L-aspartate)|interpro:IPR000246(Peptidase T2, asparaginase 2)|interpro:IPR029055|interpro:IPR033844|mint:Q8C0M9|reactome:R-MMU-8964208 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:mIymO86AHiWEAXMs6/mzjWip6QU227377 rogid:wiexavwMdQbxSvFKT3feeH1J0+010090 rigid:/cEw0EPStUhCo75SRdRkcT0FUgs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8R3P0 uniprotkb:Q83BP6 intact:EBI-8319421|uniprotkb:Q5SV07|intact:MINT-4086826|uniprotkb:Q9DCE2|uniprotkb:Q9JIN8|uniprotkb:Q9D876|ensembl:ENSMUSP00000021119|ensembl:ENSMUSP00000139318 intact:EBI-21286233|ensemblbacteria:AAO90954 psi-mi:acy2_mouse(display_long)|uniprotkb:Aspa(gene name)|psi-mi:Aspa(display_short)|uniprotkb:Aminoacylase-2(gene name synonym) psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287208|imex:IM-26899-411 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006532073.2|refseq:NP_075602.2|refseq:XP_006532074.1|refseq:XP_006532075.1|ensembl:ENSMUSG00000020774(gene)|ensembl:ENSMUST00000021119(transcript)|ensembl:ENSMUST00000184572(transcript)|go:"GO:0004046"(aminoacylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006083"(acetate metabolic process)|go:"GO:0016788"(hydrolase activity, acting on ester bonds)|go:"GO:0016811"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides")|go:"GO:0019807"(aspartoacylase activity)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|interpro:IPR007036(Succinylglutamate desuccinylase/aspartoacylase)|interpro:IPR016708(Aspartoacylase)|mint:Q8R3P0|reactome:R-MMU-8963693 ensemblbacteria:AAO90954(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|ensemblbacteria:CBU_1457(gene)|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q83BP6 - comment:mint|function:"Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter" - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:vitURXLxvpEcn30yhdWtofbS+wg10090 rogid:mIymO86AHiWEAXMs6/mzjWip6QU227377 rigid:wKEOw/LoC6FNBxOp4JKhVF/75C8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83BP6 uniprotkb:Q8CBW3 intact:EBI-21286233|ensemblbacteria:AAO90954 intact:EBI-375511|uniprotkb:Q3U8V0|uniprotkb:Q60747|uniprotkb:Q91ZM5|uniprotkb:Q923I9|uniprotkb:Q99KH4|ensembl:ENSMUSP00000118491 psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name) psi-mi:abi1_mouse(display_long)|uniprotkb:Abi1(gene name)|psi-mi:Abi1(display_short)|uniprotkb:Ssh3bp1(gene name synonym)|uniprotkb:Abelson interactor 1(gene name synonym)|uniprotkb:Spectrin SH3 domain-binding protein 1(gene name synonym)|uniprotkb:Eps8 SH3 domain-binding protein(gene name synonym)|uniprotkb:e3B1(gene name synonym)|uniprotkb:Ablphilin-1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287202|imex:IM-26899-275 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90954(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|ensemblbacteria:CBU_1457(gene)|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q83BP6 refseq:NP_031406.2|refseq:NP_001070658.1|refseq:NP_001070660.1|refseq:NP_001070661.1|ensembl:ENSMUSG00000058835(gene)|ensembl:ENSMUST00000123948(transcript)|go:"GO:0001756"(somitogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030296"(protein tyrosine kinase activator activity)|go:"GO:0030426"(growth cone)|go:"GO:0031209"(SCAR complex)|go:"GO:0031252"(cell leading edge)|go:"GO:0032433"(filopodium tip)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0043005"(neuron projection)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028456|interpro:IPR028457|interpro:IPR035725|interpro:IPR036028|mint:Q8CBW3|reactome:R-MMU-2029482|reactome:R-MMU-4420097|reactome:R-MMU-5663213|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013423|dip:DIP-29534N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:mIymO86AHiWEAXMs6/mzjWip6QU227377 rogid:mDXRmY9uUy6POYZDWeVlwDPxAIs10090 rigid:wcPk2gkuRGnF32IcdAzKucfds9A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83C21 uniprotkb:Q8BTM8 intact:EBI-21286157|ensemblbacteria:AAO90819 intact:EBI-641991|uniprotkb:B7FAV0|uniprotkb:O54934|uniprotkb:Q7TQI1|uniprotkb:Q8BLK1|uniprotkb:Q8BTN7|uniprotkb:Q8VHX5|uniprotkb:Q8VHX8|uniprotkb:Q99KQ2|ensembl:ENSMUSP00000033699 psi-mi:q83c21_coxbu(display_long)|uniprotkb:CBU_1314(locus name) psi-mi:flna_mouse(display_long)|uniprotkb:Alpha-filamin(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Endothelial actin-binding protein(gene name synonym)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Non-muscle filamin(gene name synonym)|uniprotkb:Flna(gene name)|psi-mi:Flna(display_short)|uniprotkb:Fln(gene name synonym)|uniprotkb:Fln1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287196|imex:IM-26899-607 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90819(transcript)|ensemblbacteria:CBU_1314(gene)|refseq:NP_820305.2|refseq:WP_010958144.1|mint:Q83C21 refseq:XP_006527974.1|ensembl:ENSMUST00000033699(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007195"(adenylate cyclase-inhibiting dopamine receptor signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0019900"(kinase binding)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0021987"(cerebral cortex development)|ensembl:ENSMUSG00000031328(gene)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0046332"(SMAD binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050808"(synapse organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060271"(cilium assembly)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030426"(growth cone)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031523"(Myb complex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0032231"(regulation of actin filament bundle assembly)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0097440"(apical dendrite)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|go:"GO:1905000"(regulation of membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:1905031"(regulation of membrane repolarization during cardiac muscle cell action potential)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|go:"GO:0097368"(establishment of Sertoli cell barrier)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:Q8BTM8|reactome:R-MMU-114608|reactome:R-MMU-430116|reactome:R-MMU-446353|reactome:R-MMU-5627123 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:DIFe5BH2MWRB3uuIhKXumw9z8+w227377 rogid:hp3whHs7nFMTtChpQ/KywkPalq810090 rigid:TPc3xv5+lz0oCHn2tczKhIukVKo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q80YV2 uniprotkb:Q83BP6 intact:EBI-8458917|uniprotkb:Q80Z11|uniprotkb:Q3TJE6|uniprotkb:Q8R3U7|uniprotkb:Q8CI56|uniprotkb:Q8BTW5|intact:MINT-4112467|ensembl:ENSMUSP00000079627 intact:EBI-21286233|ensemblbacteria:AAO90954 psi-mi:nipa_mouse(display_long)|uniprotkb:Zc3hc1(gene name)|psi-mi:Zc3hc1(display_short)|uniprotkb:Nipa(gene name synonym)|uniprotkb:Nuclear-interacting partner of anaplastic lymphoma kinase(gene name synonym)|uniprotkb:Zinc finger C3HC-type protein 1(gene name synonym) psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287384|imex:IM-26899-613 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766323.1|refseq:NP_001298015.1|refseq:XP_017177060.1|ensembl:ENSMUSG00000039130(gene)|ensembl:ENSMUST00000080812(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051301"(cell division)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR012935(Zinc finger, C3HC-like)|interpro:IPR013909(mRNA export, Rsm1-like)|mint:Q80YV2 ensemblbacteria:AAO90954(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|ensemblbacteria:CBU_1457(gene)|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q83BP6 - comment:mint|function:"Essential component of an SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry (By similarity). Overexpression may be able to protect from apoptosis induced by IL-3 withdrawal" - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:Oof53JrNMhcVPnAE+d4UVV2A2PA10090 rogid:mIymO86AHiWEAXMs6/mzjWip6QU227377 rigid:4ladTM7RxYiJsBk8joHoiiVifvI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83BP6 uniprotkb:Q9ERF3 intact:EBI-21286233|ensemblbacteria:AAO90954 intact:EBI-6094557|uniprotkb:Q3U562|uniprotkb:Q9CZP1|ensembl:ENSMUSP00000056359|ensembl:ENSMUSP00000113560 psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name) psi-mi:wdr61_mouse(display_long)|uniprotkb:Wdr61(gene name)|psi-mi:Wdr61(display_short)|uniprotkb:Meiotic recombination REC14 protein homolog(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287378|imex:IM-26899-183 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90954(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|ensemblbacteria:CBU_1457(gene)|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q83BP6 refseq:NP_001020546.1|refseq:NP_075680.1|ensembl:ENSMUSG00000061559(gene)|ensembl:ENSMUST00000051822(transcript)|ensembl:ENSMUST00000121204(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0055087"(Ski complex)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9ERF3|reactome:R-MMU-112382|reactome:R-MMU-429958|reactome:R-MMU-674695|reactome:R-MMU-75955|reactome:R-MMU-8866654 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:mIymO86AHiWEAXMs6/mzjWip6QU227377 rogid:r5TxJiuiFNk5dUDuhzCqFfFXX/M10090 rigid:0SQX/Co/ZPV2bn8wqT+Bq4F2BWg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83BP6 uniprotkb:Q64727 intact:EBI-21286233|ensemblbacteria:AAO90954 intact:EBI-432047|uniprotkb:Q8BP32|uniprotkb:Q8BS46|uniprotkb:Q922C5|uniprotkb:Q922D9|ensembl:ENSMUSP00000022369 psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name) psi-mi:vinc_mouse(display_long)|uniprotkb:Metavinculin(gene name synonym)|uniprotkb:Vcl(gene name)|psi-mi:Vcl(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287372|imex:IM-26899-77 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90954(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|ensemblbacteria:CBU_1457(gene)|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q83BP6 refseq:NP_033528.3|ensembl:ENSMUSG00000021823(gene)|ensembl:ENSMUST00000022369(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0002102"(podosome)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042383"(sarcolemma)|go:"GO:0043297"(apical junction assembly)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045121"(membrane raft)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0048675"(axon extension)|go:"GO:0043034"(costamere)|go:"GO:0051015"(actin filament binding)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0090636"(outer dense plaque of desmosome)|go:"GO:0090637"(inner dense plaque of desmosome)|go:"GO:1903140"(regulation of establishment of endothelial barrier)|go:"GO:1904702"(regulation of protein localization to adherens junction)|go:"GO:1990357"(terminal web)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR017997|interpro:IPR036723|mint:Q64727|rcsb pdb:5Y04|reactome:R-MMU-114608|reactome:R-MMU-445355|reactome:R-MMU-5674135|reactome:R-MMU-6798695 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:mIymO86AHiWEAXMs6/mzjWip6QU227377 rogid:bfHsrHTLESS6CIctYpg0yX3N+UA10090 rigid:A1XarRTAaJkiD9o37M0hjZkMlbg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83BP6 uniprotkb:O55013 intact:EBI-21286233|ensemblbacteria:AAO90954 intact:EBI-1172223|ensembl:ENSMUSP00000030660 psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name) psi-mi:tppc3_mouse(display_long)|uniprotkb:BET3 homolog(gene name synonym)|uniprotkb:Trappc3(gene name)|psi-mi:Trappc3(display_short)|uniprotkb:Bet3(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287366|imex:IM-26899-75 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90954(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|ensemblbacteria:CBU_1457(gene)|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q83BP6 ensembl:ENSMUSG00000028847(gene)|ensembl:ENSMUST00000030660(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030008"(TRAPP complex)|go:"GO:0033106"(cis-Golgi network membrane)|interpro:IPR007194("Transport protein particle (TRAPP) component, Bet3")|interpro:IPR016721(TRAPP I complex, Bet3)|interpro:IPR024096|mint:O55013|rcsb pdb:1WC8|rcsb pdb:1WC9|rcsb pdb:2J3R|rcsb pdb:2J3T|rcsb pdb:2J3W|rcsb pdb:2PWN|reactome:R-MMU-204005|reactome:R-MMU-8876198|refseq:NP_038746.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:mIymO86AHiWEAXMs6/mzjWip6QU227377 rogid:VoANjtqe/P6oziS0WRdNJprvMUI10090 rigid:XzgPd5o10CkHDPDedPEGMV7V2JA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83BP6 uniprotkb:Q9QZ06 intact:EBI-21286233|ensemblbacteria:AAO90954 intact:EBI-74272|uniprotkb:Q543N1|uniprotkb:Q9D5P5|ensembl:ENSMUSP00000001950 psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name) psi-mi:tolip_mouse(display_long)|uniprotkb:Tollip(gene name)|psi-mi:Tollip(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287360|imex:IM-26899-281 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90954(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|ensemblbacteria:CBU_1457(gene)|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q83BP6 refseq:NP_076253.1|ensembl:ENSMUSG00000025139(gene)|ensembl:ENSMUST00000001950(transcript)|go:"GO:0005150"(interleukin-1, type I receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0016310"(phosphorylation)|go:"GO:0016604"(nuclear body)|go:"GO:0019900"(kinase binding)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|interpro:IPR035892|interpro:IPR037301|interpro:IPR041799|mint:Q9QZ06|reactome:R-MMU-6798695|reactome:R-MMU-9020702 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:mIymO86AHiWEAXMs6/mzjWip6QU227377 rogid:l31YAZvuxJMK48wHqwvgPu8lVUs10090 rigid:FoAAyJKjNu7v6ttNk8tac3Zjpwc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83BP6 uniprotkb:Q3V0K9 intact:EBI-21286233|ensemblbacteria:AAO90954 intact:EBI-1183739|ensembl:ENSMUSP00000091317 psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name) psi-mi:plsi_mouse(display_long)|uniprotkb:Pls1(gene name)|psi-mi:Pls1(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287299|imex:IM-26899-413 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90954(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|ensemblbacteria:CBU_1457(gene)|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q83BP6 refseq:NP_001028382.1|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR030235|interpro:IPR036872|interpro:IPR039959|mint:Q3V0K9|go:"GO:0005903"(brush border)|go:"GO:0032420"(stereocilium)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051639"(actin filament network formation)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060121"(vestibular receptor cell stereocilium organization)|go:"GO:1902896"(terminal web assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990357"(terminal web)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|refseq:XP_006510809.1|refseq:XP_006510810.1|ensembl:ENSMUSG00000049493(gene)|ensembl:ENSMUST00000093800(transcript)|go:"GO:0001951"(intestinal D-glucose absorption)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament) - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:mIymO86AHiWEAXMs6/mzjWip6QU227377 rogid:rD1284OOqhjdTNQrrW0IWT9p4VU10090 rigid:HsWbTtcB270FX1QleSgP0B3atLI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83BP6 uniprotkb:Q9Z1W9 intact:EBI-21286233|ensemblbacteria:AAO90954 intact:EBI-444764|uniprotkb:Q80W13|ensembl:ENSMUSP00000099776 psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name) psi-mi:stk39_mouse(display_long)|uniprotkb:Serine/threonine-protein kinase 39(gene name synonym)|uniprotkb:Stk39(gene name)|psi-mi:Stk39(display_short)|uniprotkb:Spak(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287348|imex:IM-26899-73 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90954(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|ensemblbacteria:CBU_1457(gene)|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q83BP6 refseq:NP_058562.1|ensembl:ENSMUSG00000027030(gene)|ensembl:ENSMUST00000102715(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032414"(positive regulation of ion transmembrane transporter activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036438"(maintenance of lens transparency)|go:"GO:0038146"("chemokine (C-X-C motif) ligand 12 signaling pathway")|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050801"(ion homeostasis)|go:"GO:0071476"(cellular hypotonic response)|go:"GO:0090188"(negative regulation of pancreatic juice secretion)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1905408"(negative regulation of creatine transmembrane transporter activity)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024678|mint:Q9Z1W9|rcsb pdb:5D9H|rcsb pdb:5DBX|dip:DIP-31911N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:mIymO86AHiWEAXMs6/mzjWip6QU227377 rogid:iZk2DNNQxkBwjRvl0DNNt2YZcSc10090 rigid:D+hTbmWDozgKomZ0tEMT1FvW4ZQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83BP6 uniprotkb:P50636 intact:EBI-21286233|ensemblbacteria:AAO90954 intact:EBI-3508340|uniprotkb:Q3UGT2|uniprotkb:Q9QUJ5|ensembl:ENSMUSP00000022890 psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name) psi-mi:rn19a_mouse(display_long)|uniprotkb:Rnf19a(gene name)|psi-mi:Rnf19a(display_short)|uniprotkb:Geg-154(gene name synonym)|uniprotkb:Rnf19(gene name synonym)|uniprotkb:Xybp(gene name synonym)|uniprotkb:Double ring-finger protein(gene name synonym)|uniprotkb:Gametogenesis-expressed protein GEG-154(gene name synonym)|uniprotkb:RING finger protein 19A(gene name synonym)|uniprotkb:UBCM4-interacting protein 117(gene name synonym)|uniprotkb:XY body protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287342|imex:IM-26899-711 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90954(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|ensemblbacteria:CBU_1457(gene)|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q83BP6 refseq:NP_038951.1|ensembl:ENSMUSG00000022280(gene)|ensembl:ENSMUST00000022890(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099576"(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR031127|interpro:IPR044066|mint:P50636|reactome:R-MMU-983168 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:mIymO86AHiWEAXMs6/mzjWip6QU227377 rogid:kmmYnA5DGyrDuK1Px3uyV6iqlG810090 rigid:AvFfC+tiviUTO8twWH/S3sn5614 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83BP6 uniprotkb:P22605 intact:EBI-21286233|ensemblbacteria:AAO90954 intact:EBI-2903247|uniprotkb:P11417|uniprotkb:P22604 psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name) psi-mi:rarb_mouse(display_long)|uniprotkb:Rarb(gene name)|psi-mi:Rarb(display_short)|uniprotkb:Nr1b2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287336|imex:IM-26899-611 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90954(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|ensemblbacteria:CBU_1457(gene)|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q83BP6 go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001657"(ureteric bud development)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003417"(growth plate cartilage development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0021756"(striatum development)|go:"GO:0022008"(neurogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048048"(embryonic eye morphogenesis)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048566"(embryonic digestive tract development)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0060348"(bone development)|go:"GO:0061037"(negative regulation of cartilage development)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|rcsb pdb:1XDK|reactome:R-MMU-383280|reactome:R-MMU-5362517|go:"GO:0043068"(positive regulation of programmed cell death)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|refseq:NP_001276689.1|refseq:NP_001276690.1|refseq:NP_001276691.1|refseq:NP_035373.1|interpro:IPR035500|mint:P22605 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:mIymO86AHiWEAXMs6/mzjWip6QU227377 rogid:jsfH728g22P17Xkv1lfsyBLPwgE10090 rigid:LpwvmIbR9KKyjaQ4QZtWG8DECOM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83BP6 uniprotkb:Q8R1Z4 intact:EBI-21286233|ensemblbacteria:AAO90954 intact:EBI-21287305|ensembl:ENSMUSP00000027049|uniprotkb:Q9D5M1|uniprotkb:Q9DAF9 psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name) psi-mi:ppr42_mouse(display_long)|uniprotkb:Ppp1r42(gene name)|psi-mi:Ppp1r42(display_short)|uniprotkb:Lrrc67(gene name synonym)|uniprotkb:Leucine-rich repeat-containing protein 67(gene name synonym)|uniprotkb:Testis leucine-rich repeat protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287330|imex:IM-26899-797 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90954(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|ensemblbacteria:CBU_1457(gene)|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q83BP6 ensembl:ENSMUSG00000025916(gene)|ensembl:ENSMUST00000027049(transcript)|go:"GO:0002177"(manchette)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0010921"(regulation of phosphatase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0070840"(dynein complex binding)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR025875|interpro:IPR032675|mint:Q8R1Z4|refseq:NP_663730.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:mIymO86AHiWEAXMs6/mzjWip6QU227377 rogid:OEuz7C5/7qxHPsKscCe0o0cwhAM10090 rigid:+NBg5fHT61dQ+BjaZje2p5WWnsg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83BP6 uniprotkb:Q8CHC4 intact:EBI-21286233|ensemblbacteria:AAO90954 intact:EBI-775693 psi-mi:q83bp6_coxbu(display_long)|uniprotkb:CBU_1457(locus name) psi-mi:synj1_mouse(display_long)|uniprotkb:Synj1(gene name)|psi-mi:Synj1(display_short)|uniprotkb:Kiaa0910(gene name synonym)|uniprotkb:Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287354|imex:IM-26899-415 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90954(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|ensemblbacteria:CBU_1457(gene)|refseq:NP_820440.1|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q83BP6 interpro:IPR015047(Region of unknown function DUF1866)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002013(Synaptojanin, N-terminal)|interpro:IPR034971|interpro:IPR034972|interpro:IPR035979|interpro:IPR036691|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:Q8CHC4|go:"GO:0003723"(RNA binding)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014015"(positive regulation of gliogenesis)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030118"(clathrin coat)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034097"(response to cytokine)|go:"GO:0034595"(phosphatidylinositol phosphate 5-phosphatase activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043195"(terminal bouton)|go:"GO:0043812"(phosphatidylinositol-4-phosphate phosphatase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0052658"(inositol-1,4,5-trisphosphate 5-phosphatase activity)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1903423"(positive regulation of synaptic vesicle recycling)|go:"GO:1904980"(positive regulation of endosome organization)|go:"GO:1990175"(EH domain binding)|reactome:R-MMU-1660499|reactome:R-MMU-1855183|reactome:R-MMU-1855204|reactome:R-MMU-8856828 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:mIymO86AHiWEAXMs6/mzjWip6QU227377 rogid:jBMEFlptiz90uS1F1ajBc7zR3vo10090 rigid:8rOqoLA3lovkCeiJzw7RQOlL8ko false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83BP3 uniprotkb:Q9CWB7 intact:EBI-21287390|ensemblbacteria:AAO90957 intact:EBI-21287402|ensembl:ENSMUSP00000025488|ensembl:ENSMUSP00000116181 psi-mi:q83bp3_coxbu(display_long)|uniprotkb:CBU_1460(locus name) psi-mi:yd286_mouse(display_long) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287421|imex:IM-26899-615 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90957(transcript)|ensemblbacteria:CBU_1460(gene)|refseq:NP_820443.1|refseq:WP_010958241.1|mint:Q83BP3 ensembl:ENSMUSG00000024592(gene)|ensembl:ENSMUST00000025488(transcript)|go:"GO:0005739"(mitochondrion)|interpro:IPR008554(Glutaredoxin 2)|interpro:IPR036249|mint:Q9CWB7|rcsb pdb:1WJK|ensembl:ENSMUST00000139243(transcript)|refseq:NP_084185.1|refseq:XP_006526410.1|refseq:XP_006526411.1|refseq:XP_006526412.1|refseq:XP_006526413.1|refseq:XP_006526414.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:2+R10/I42+7H8F9IZGtpD4GuETg227377 rogid:XUVXQZuntCxsS6Q6Tja/r8CGXFM10090 rigid:nuGuTVReVxORoAENbBzMhrAYKU0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83BP3 uniprotkb:Q3UNW5 intact:EBI-21287390|ensemblbacteria:AAO90957 intact:EBI-5691372|uniprotkb:Q99PF2|uniprotkb:Q14AW3|ensembl:ENSMUSP00000027629 psi-mi:q83bp3_coxbu(display_long)|uniprotkb:CBU_1460(locus name) psi-mi:tf2l1_mouse(display_long)|uniprotkb:Tfcp2l1(gene name)|psi-mi:Tfcp2l1(display_short)|uniprotkb:CP2-related transcriptional repressor 1(gene name synonym)|uniprotkb:Crtr1(gene name synonym)|uniprotkb:Tcfcp2l1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287396|imex:IM-26899-185 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90957(transcript)|ensemblbacteria:CBU_1460(gene)|refseq:NP_820443.1|refseq:WP_010958241.1|mint:Q83BP3 refseq:NP_076244.2|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002070"(epithelial cell maturation)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007028"(cytoplasm organization)|go:"GO:0007431"(salivary gland development)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016020"(membrane)|go:"GO:0045927"(positive regulation of growth)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037598|interpro:IPR041418|mint:Q3UNW5|ensembl:ENSMUSG00000026380(gene)|ensembl:ENSMUST00000027629(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific) - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:2+R10/I42+7H8F9IZGtpD4GuETg227377 rogid:QtzNiWQU27XK2s0idF91/IAVi0E10090 rigid:L7sVP8eu8h0Q9Wl9Q7hgYEsxbu8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8R3P0 uniprotkb:Q83B01 intact:EBI-8319421|uniprotkb:Q5SV07|intact:MINT-4086826|uniprotkb:Q9DCE2|uniprotkb:Q9JIN8|uniprotkb:Q9D876|ensembl:ENSMUSP00000021119|ensembl:ENSMUSP00000139318 intact:EBI-21286307|ensemblbacteria:AAO91219 psi-mi:acy2_mouse(display_long)|uniprotkb:Aspa(gene name)|psi-mi:Aspa(display_short)|uniprotkb:Aminoacylase-2(gene name synonym) psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287588|imex:IM-26899-417 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006532073.2|refseq:NP_075602.2|refseq:XP_006532074.1|refseq:XP_006532075.1|ensembl:ENSMUSG00000020774(gene)|ensembl:ENSMUST00000021119(transcript)|ensembl:ENSMUST00000184572(transcript)|go:"GO:0004046"(aminoacylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006083"(acetate metabolic process)|go:"GO:0016788"(hydrolase activity, acting on ester bonds)|go:"GO:0016811"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides")|go:"GO:0019807"(aspartoacylase activity)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|interpro:IPR007036(Succinylglutamate desuccinylase/aspartoacylase)|interpro:IPR016708(Aspartoacylase)|mint:Q8R3P0|reactome:R-MMU-8963693 ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 - comment:mint|function:"Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter" - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:vitURXLxvpEcn30yhdWtofbS+wg10090 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rigid:0caGIaxi8fiA0qCRPB1wK0dO3jE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P16460 uniprotkb:Q83B01 intact:EBI-8311897|ensembl:ENSMUSP00000099904|intact:MINT-1856903 intact:EBI-21286307|ensemblbacteria:AAO91219 psi-mi:assy_mouse(display_long)|uniprotkb:Ass1(gene name)|psi-mi:Ass1(display_short)|uniprotkb:Ass(gene name synonym)|uniprotkb:Citrulline--aspartate ligase(gene name synonym) psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287594|imex:IM-26899-291 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000076441(gene)|ensembl:ENSMUST00000102840(transcript)|go:"GO:0000050"(urea cycle)|go:"GO:0000052"(citrulline metabolic process)|go:"GO:0000053"(argininosuccinate metabolic process)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0004055"(argininosuccinate synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006526"(arginine biosynthetic process)|go:"GO:0006531"(aspartate metabolic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0007494"(midgut development)|go:"GO:0007568"(aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0007623"(circadian rhythm)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010046"(response to mycotoxin)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016597"(amino acid binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0060416"(response to growth hormone)|go:"GO:0060539"(diaphragm development)|go:"GO:0070852"(cell body fiber)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071242"(cellular response to ammonium ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071377"(cellular response to glucagon stimulus)|go:"GO:0071400"(cellular response to oleic acid)|go:"GO:0071418"(cellular response to amine stimulus)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:1903038"(negative regulation of leukocyte cell-cell adhesion)|interpro:IPR001518(Argininosuccinate synthase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR018223|interpro:IPR023434|interpro:IPR024074|mint:P16460|reactome:R-MMU-70635|go:"GO:0071230"(cellular response to amino acid stimulus)|refseq:NP_031520.1 ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 - comment:mint - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:ZFoIkgXjhjFrOtq5spUUqnMdaHM10090 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rigid:f9TMiR/zxl1bTOCGpYdr7xg9HyY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5XJY5 uniprotkb:Q83B01 intact:EBI-8323149|uniprotkb:Q91W48|intact:MINT-1857447|ensembl:ENSMUSP00000034607 intact:EBI-21286307|ensemblbacteria:AAO91219 psi-mi:copd_mouse(display_long)|uniprotkb:Arcn1(gene name)|psi-mi:Arcn1(display_short)|uniprotkb:Archain(gene name synonym)|uniprotkb:Copd(gene name synonym)|uniprotkb:Delta-coat protein(gene name synonym) psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287576|imex:IM-26899-617 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_666097.3|ensembl:ENSMUSG00000032096(gene)|ensembl:ENSMUST00000034607(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0015031"(protein transport)|go:"GO:0021691"(cerebellar Purkinje cell layer maturation)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0043473"(pigmentation)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0051645"(Golgi localization)|interpro:IPR011012(Longin-like)|interpro:IPR022775|interpro:IPR027059|interpro:IPR028565|interpro:IPR036168|mint:Q5XJY5|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-MMU-6807878|reactome:R-MMU-6811434 ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 - comment:mint - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:9DuViv4OSAkhnWe4lDxw1efwckE10090 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rigid:8Jg4es4bOFigyWMCijZruVHzi6Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:Q9Z1T1 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-643061|uniprotkb:E9QQ08|uniprotkb:Q91YR4|ensembl:ENSMUSP00000022196 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:ap3b1_mouse(display_long)|uniprotkb:Adaptor protein complex AP-3 subunit beta-1(gene name synonym)|uniprotkb:Beta-3A-adaptin(gene name synonym)|uniprotkb:Clathrin assembly protein complex 3 beta-1 large chain(gene name synonym)|uniprotkb:Ap3b1(gene name)|psi-mi:Ap3b1(display_short)|uniprotkb:Adaptor-related protein complex 3 subunit beta-1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287570|imex:IM-26899-521 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 refseq:NP_033810.2|ensembl:ENSMUSG00000021686(gene)|ensembl:ENSMUST00000022196(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003016"(respiratory system process)|go:"GO:0005739"(mitochondrion)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006829"(zinc ion transport)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006954"(inflammatory response)|go:"GO:0007040"(lysosome organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0016182"(synaptic vesicle budding from endosome)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030324"(lung development)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0032438"(melanosome organization)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0043473"(pigmentation)|go:"GO:0045202"(synapse)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048007"(antigen processing and presentation, exogenous lipid antigen via MHC class Ib)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051138"(positive regulation of NK T cell differentiation)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0061024"(membrane organization)|go:"GO:0090152"(establishment of protein localization to mitochondrial membrane involved in mitochondrial fission)|go:"GO:0098773"(skin epidermis development)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026739|interpro:IPR026740|interpro:IPR029390|interpro:IPR029394|mint:Q9Z1T1|reactome:R-MMU-432722|dip:DIP-49018N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:Xtcoo5Kk0ZYpVbr+WEBfVxidkVU10090 rigid:6RMtqQF0In3AJYt0a8yFQJTHjXI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:Q8K298 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-2553580|uniprotkb:Q8BL79|uniprotkb:Q8BLB3|uniprotkb:Q9CUY0|uniprotkb:Q8K2N0|ensembl:ENSMUSP00000045873 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:anln_mouse(display_long)|uniprotkb:Anln(gene name)|psi-mi:Anln(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287564|imex:IM-26899-289 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 ensembl:ENSMUSG00000036777(gene)|ensembl:ENSMUST00000040912(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030496"(midbody)|go:"GO:0031106"(septin ring organization)|go:"GO:0032059"(bleb)|go:"GO:0090521"(glomerular visceral epithelial cell migration)|go:"GO:0099738"(cell cortex region)|go:"GO:1904172"(positive regulation of bleb assembly)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012966(Protein of unknown function DUF1709, fungi)|interpro:IPR031970|interpro:IPR037840|mint:Q8K298|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|refseq:NP_082666.2 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:EO+oGgohw0Ee5W3sDVXSpfF29dA10090 rigid:KBjtfTwfug79cr8/uzBktSkSqfc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:Q8C4Q6 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-9686885|uniprotkb:Q3U6V0|uniprotkb:Q3UP85|uniprotkb:Q6NXY2|uniprotkb:Q6PG77|uniprotkb:Q78W09|uniprotkb:Q99K80|ensembl:ENSMUSP00000104795 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:aida_mouse(display_long)|uniprotkb:Aida(gene name)|psi-mi:Aida(display_short)|uniprotkb:Axin interaction partner and dorsalization antagonist(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287558|imex:IM-26899-287 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 refseq:NP_859421.1|ensembl:ENSMUSG00000042901(gene)|ensembl:ENSMUST00000109166(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048264"(determination of ventral identity)|go:"GO:2000016"(negative regulation of determination of dorsal identity)|interpro:IPR023421|interpro:IPR025939|interpro:IPR035892|interpro:IPR036818|mint:Q8C4Q6|rcsb pdb:1UG7|rcsb pdb:2QZ5|go:"GO:0016020"(membrane) - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:/SC2FEJlL5Wj2Us2tgwnKSJvWa410090 rigid:y3i/HXzIUcu3qYT+Hx7sSNwFOU4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:P28271 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-21287509|ensembl:ENSMUSP00000100038|uniprotkb:Q3TQ15|uniprotkb:Q99K54 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:acohc_mouse(display_long)|uniprotkb:Aco1(gene name)|psi-mi:Aco1(display_short)|uniprotkb:Ireb1(gene name synonym)|uniprotkb:Irebp(gene name synonym)|uniprotkb:Citrate hydro-lyase(gene name synonym)|uniprotkb:Iron regulatory protein 1(gene name synonym)|uniprotkb:Iron-responsive element-binding protein 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287552|imex:IM-26899-801 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 ensembl:ENSMUSG00000028405(gene)|ensembl:ENSMUST00000102973(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003994"(aconitate hydratase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006101"(citrate metabolic process)|go:"GO:0006417"(regulation of translation)|reactome:R-MMU-917937|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030350"(iron-responsive element binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|interpro:IPR001030(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)|interpro:IPR006249(Aconitase/iron regulatory protein 2)|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR015931(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomains 1 and 3)|interpro:IPR018136|interpro:IPR029784|interpro:IPR036008|interpro:IPR044137|mint:P28271|go:"GO:0046872"(metal ion binding)|go:"GO:0047780"(citrate dehydratase activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0051538"(3 iron, 4 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|refseq:NP_031412.2 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:v7B64J3GYN+jIsEO9BPIgi7ELBQ10090 rigid:EFY4IEmeSlR8mKGZ5H4Crzv8INU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83BF4 uniprotkb:Q64700 intact:EBI-21286294|ensemblbacteria:AAO91053 intact:EBI-2271232|uniprotkb:Q3TVP8|ensembl:ENSMUSP00000034091 psi-mi:q83bf4_coxbu(display_long)|uniprotkb:CBU_1556(locus name) psi-mi:rbl2_mouse(display_long)|uniprotkb:Rbl2(gene name)|psi-mi:Rbl2(display_short)|uniprotkb:Retinoblastoma-related protein 2(gene name synonym)|uniprotkb:130 kDa retinoblastoma-associated protein(gene name synonym)|uniprotkb:pRb2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287503|imex:IM-26899-187 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91053(transcript)|ensemblbacteria:CBU_1556(gene)|go:"GO:0016021"(integral component of membrane)|refseq:NP_820539.1|refseq:WP_010958299.1|mint:Q83BF4 refseq:NP_035380.3|refseq:NP_001268929.1|refseq:NP_001268930.1|ensembl:ENSMUSG00000031666(gene)|ensembl:ENSMUST00000034091(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0043550"(regulation of lipid kinase activity)|go:"GO:0051302"(regulation of cell division)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028308|interpro:IPR028309|interpro:IPR036915|mint:Q64700|reactome:R-MMU-1538133|reactome:R-MMU-69231 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:FPvBIpxYSACDYC5jEm0L73i9Pfs227377 rogid:gWnytGkST3SKjCgR8YTzaHuR+RA10090 rigid:CbRwZR68FZXPT6v5JhWvGNEVJNw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q61586 uniprotkb:Q83BF4 intact:EBI-8391354|uniprotkb:Q8VCT2|intact:MINT-4119610|ensembl:ENSMUSP00000057635|ensembl:ENSMUSP00000157722|ensembl:ENSMUSP00000158322 intact:EBI-21286294|ensemblbacteria:AAO91053 psi-mi:gpat1_mouse(display_long)|uniprotkb:Gpam(gene name)|psi-mi:Gpam(display_short)|uniprotkb:Gpat1(gene name synonym)|uniprotkb:P90(gene name synonym) psi-mi:q83bf4_coxbu(display_long)|uniprotkb:CBU_1556(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287497|imex:IM-26899-79 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011245449.1|refseq:NP_032175.2|refseq:XP_006526755.1|refseq:XP_006526756.1|refseq:XP_006526757.1|ensembl:ENSMUSG00000024978(gene)|ensembl:ENSMUST00000061856(transcript)|ensembl:ENSMUST00000235957(transcript)|ensembl:ENSMUST00000237146(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0004366"(glycerol-3-phosphate O-acyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006072"(glycerol-3-phosphate metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006637"(acyl-CoA metabolic process)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006650"(glycerophospholipid metabolic process)|go:"GO:0006651"(diacylglycerol biosynthetic process)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0006655"(phosphatidylglycerol biosynthetic process)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0009749"(response to glucose)|go:"GO:0010867"(positive regulation of triglyceride biosynthetic process)|go:"GO:0014823"(response to activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016024"(CDP-diacylglycerol biosynthetic process)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0051607"(defense response to virus)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0055091"(phospholipid homeostasis)|go:"GO:0070236"(negative regulation of activation-induced cell death of T cells)|go:"GO:0102420"("sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity")|interpro:IPR002123(Phospholipid/glycerol acyltransferase)|interpro:IPR022284|interpro:IPR028354|interpro:IPR041728|mint:Q61586|reactome:R-MMU-1483166|reactome:R-MMU-75109 ensemblbacteria:AAO91053(transcript)|ensemblbacteria:CBU_1556(gene)|go:"GO:0016021"(integral component of membrane)|refseq:NP_820539.1|refseq:WP_010958299.1|mint:Q83BF4 - comment:mint - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:TGoi5HJQf7/bMY4eJh07Y9w+65I10090 rogid:FPvBIpxYSACDYC5jEm0L73i9Pfs227377 rigid:w25gaxEldl/w5CoMBG+ekMiO3tY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83BF4 uniprotkb:O35493 intact:EBI-21286294|ensemblbacteria:AAO91053 intact:EBI-21287458|ensembl:ENSMUSP00000090820|uniprotkb:O35721|uniprotkb:Q8CEU9|uniprotkb:Q99LU6 psi-mi:q83bf4_coxbu(display_long)|uniprotkb:CBU_1556(locus name) psi-mi:clk4_mouse(display_long)|uniprotkb:Clk4(gene name)|psi-mi:Clk4(display_short)|uniprotkb:CDC-like kinase 4(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287491|imex:IM-26899-519 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91053(transcript)|ensemblbacteria:CBU_1556(gene)|go:"GO:0016021"(integral component of membrane)|refseq:NP_820539.1|refseq:WP_010958299.1|mint:Q83BF4 interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:O35493|go:"GO:0106311"|ensembl:ENSMUSG00000020385(gene)|ensembl:ENSMUST00000093132(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|refseq:NP_001291673.1|refseq:NP_031740.1|refseq:XP_006532177.1|refseq:XP_006532178.1|refseq:XP_006532179.1|refseq:XP_006532181.1|refseq:XP_017169733.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:FPvBIpxYSACDYC5jEm0L73i9Pfs227377 rogid:NsVIvl1P3RzCjb6FpLQR1aWHFAM10090 rigid:ire8Fm0whdNUnkht4vOTnH1gj5g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61807 uniprotkb:Q83BG5 intact:EBI-7637550|ensembl:ENSMUSP00000086405|ensembl:ENSMUSP00000154936|uniprotkb:O88369|intact:MINT-7997209 intact:EBI-21287445|ensemblbacteria:AAO91040 psi-mi:snn_mouse(display_long)|uniprotkb:Snn(gene name)|psi-mi:Snn(display_short) psi-mi:q83bg5_coxbu(display_long)|uniprotkb:CBU_1543(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287452|imex:IM-26899-285 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000037972(gene)|ensembl:ENSMUST00000089011(transcript)|ensembl:ENSMUST00000228962(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR015135(Stannin transmembrane)|interpro:IPR015136(Stannin unstructured linker)|interpro:IPR015137(Stannin cytoplasmic)|interpro:IPR027435|interpro:IPR038747|mint:P61807|refseq:NP_033249.1|refseq:XP_006521943.1 go:"GO:0016021"(integral component of membrane)|ensemblbacteria:AAO91040(transcript)|ensemblbacteria:CBU_1543(gene)|refseq:NP_820526.1|refseq:WP_010958291.1|mint:Q83BG5 - comment:mint - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:P7GAKXacp/VT8+MDbiSmi302S6s10090 rogid:EeQNV1IYL0YMy+ZTmleHVidy3yk227377 rigid:N13q6lU8zywm5+naHWhoYhohB8Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83BP3 uniprotkb:Q6DIC0 intact:EBI-21287390|ensemblbacteria:AAO90957 intact:EBI-10765904 psi-mi:q83bp3_coxbu(display_long)|uniprotkb:CBU_1460(locus name) psi-mi:smca2_mouse(display_long)|uniprotkb:ATP-dependent helicase SMARCA2(gene name synonym)|uniprotkb:BRG1-associated factor 190B(gene name synonym)|uniprotkb:Protein brahma homolog(gene name synonym)|uniprotkb:SNF2-alpha(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2(gene name synonym)|uniprotkb:Smarca2(gene name)|psi-mi:Smarca2(display_short)|uniprotkb:Baf190b(gene name synonym)|uniprotkb:Brm(gene name synonym)|uniprotkb:Snf2a(gene name synonym)|uniprotkb:Snf2l2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287439|imex:IM-26899-799 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90957(transcript)|ensemblbacteria:CBU_1460(gene)|refseq:NP_820443.1|refseq:WP_010958241.1|mint:Q83BP3 mint:Q6DIC0|refseq:NP_001334368.1|refseq:NP_035546.2|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007399"(nervous system development)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035887"(aortic smooth muscle cell differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:0070615"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030088|interpro:IPR036427|interpro:IPR037259|interpro:IPR038718|reactome:R-MMU-3214858|reactome:R-MMU-8939243|dip:DIP-48888N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:2+R10/I42+7H8F9IZGtpD4GuETg227377 rogid:ZrEeTYo/qhRuM5fl1Ay0EyTOXJc10090 rigid:Cebxyf75WdSRuTgIECFq1wOHG5A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61793 uniprotkb:Q83BP3 intact:EBI-7512335|intact:MINT-1897166|uniprotkb:A2AMJ2|uniprotkb:O88584|uniprotkb:Q61130|uniprotkb:P70420|uniprotkb:P56487|ensembl:ENSMUSP00000052581|ensembl:ENSMUSP00000103197|ensembl:ENSMUSP00000103200|ensembl:ENSMUSP00000103201 intact:EBI-21287390|ensemblbacteria:AAO90957 psi-mi:lpar1_mouse(display_long)|uniprotkb:Gpcr26(gene name synonym)|uniprotkb:Lpa1(gene name synonym)|uniprotkb:Vzg1(gene name synonym)|uniprotkb:Edg2(gene name synonym)|uniprotkb:Lysophosphatidic acid receptor Edg-2(gene name synonym)|uniprotkb:Rec1.3(gene name synonym)|uniprotkb:VZG-1(gene name synonym)|uniprotkb:Lpar1(gene name)|psi-mi:Lpar1(display_short) psi-mi:q83bp3_coxbu(display_long)|uniprotkb:CBU_1460(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287433|imex:IM-26899-517 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011248230.1|refseq:XP_011248231.1|refseq:XP_011248232.1|refseq:XP_011248233.1|refseq:XP_011248234.1|refseq:XP_011248235.1|refseq:XP_011248236.1|refseq:XP_011248237.1|refseq:NP_001277415.1|refseq:NP_766577.1|refseq:NP_034466.2|ensembl:ENSMUSG00000038668(gene)|ensembl:ENSMUST00000055018(transcript)|ensembl:ENSMUST00000107571(transcript)|ensembl:ENSMUST00000107574(transcript)|ensembl:ENSMUST00000107575(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009986"(cell surface)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0019222"(regulation of metabolic process)|go:"GO:0021549"(cerebellum development)|go:"GO:0021554"(optic nerve development)|go:"GO:0022008"(neurogenesis)|go:"GO:0022038"(corpus callosum development)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032060"(bleb assembly)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0042552"(myelination)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070915"(lysophosphatidic acid receptor activity)|go:"GO:0071453"(cellular response to oxygen levels)|go:"GO:0071673"(positive regulation of smooth muscle cell chemotaxis)|go:"GO:1904566"(cellular response to 1-oleoyl-sn-glycerol 3-phosphate)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002277(EDG-2 lysophosphatidic acid receptor)|interpro:IPR004065(Lysophosphatidic acid receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P61793|reactome:R-MMU-416476|reactome:R-MMU-418594|reactome:R-MMU-419408|dip:DIP-42214N ensemblbacteria:AAO90957(transcript)|ensemblbacteria:CBU_1460(gene)|refseq:NP_820443.1|refseq:WP_010958241.1|mint:Q83BP3 - comment:mint|function:"Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins" - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:yhf0IgMrJKGv4vrABWqrgCwsHFw10090 rogid:2+R10/I42+7H8F9IZGtpD4GuETg227377 rigid:ESztNqqDoBFs/bB3F/y1Toz6j1s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JKP8 uniprotkb:Q83BP3 intact:EBI-8585664|ensembl:ENSMUSP00000087197|intact:MINT-8178504|uniprotkb:Q91VG2 intact:EBI-21287390|ensemblbacteria:AAO90957 psi-mi:chrc1_mouse(display_long)|uniprotkb:NF-YC-like protein(gene name synonym)|uniprotkb:YC-like protein 1(gene name synonym)|uniprotkb:Chrac1(gene name)|psi-mi:Chrac1(display_short)|uniprotkb:DNA polymerase epsilon subunit p15(gene name synonym) psi-mi:q83bp3_coxbu(display_long)|uniprotkb:CBU_1460(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287427|imex:IM-26899-283 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000068391(gene)|ensembl:ENSMUST00000089765(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0008623"(CHRAC)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003958(Transcription factor CBF/NF-Y/archaeal histone)|interpro:IPR009072(Histone-fold)|mint:Q9JKP8|refseq:NP_444298.1 ensemblbacteria:AAO90957(transcript)|ensemblbacteria:CBU_1460(gene)|refseq:NP_820443.1|refseq:WP_010958241.1|mint:Q83BP3 - comment:mint - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:RLi6d4iemwYdgkPviPoq+cRko2410090 rogid:2+R10/I42+7H8F9IZGtpD4GuETg227377 rigid:aev2GwQ72LB+sobFfcUFA/1gBzA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:P49442 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-1634539|uniprotkb:Q8R3L1|ensembl:ENSMUSP00000027271 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:inpp_mouse(display_long)|uniprotkb:Inpp1(gene name)|psi-mi:Inpp1(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287681|imex:IM-26899-419 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 refseq:XP_011236743.1|refseq:XP_011236744.1|refseq:NP_032410.2|ensembl:ENSMUSG00000026102(gene)|ensembl:ENSMUST00000027271(transcript)|go:"GO:0004441"(inositol-1,4-bisphosphate 1-phosphatase activity)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR000760(Inositol monophosphatase)|interpro:IPR020550|interpro:IPR020583|mint:P49442|reactome:R-MMU-1855183 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:t4RFuD+wu56aRQUDA+4C1AruITQ10090 rigid:7FENCco4YFGTl7L2Bo8zSS8O8ng false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:Q8BLU0 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-16146541|ensembl:ENSMUSP00000062171|ensembl:ENSMUSP00000105744|uniprotkb:Q6A073 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:flrt2_mouse(display_long)|uniprotkb:Flrt2(gene name)|psi-mi:Flrt2(display_short)|uniprotkb:Kiaa0405(gene name synonym)|uniprotkb:Fibronectin leucine rich transmembrane protein 2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287675|imex:IM-26899-625 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 ensembl:ENSMUSG00000047414(gene)|ensembl:ENSMUST00000057324(transcript)|ensembl:ENSMUST00000110117(transcript)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0061343"(cell adhesion involved in heart morphogenesis)|go:"GO:0071711"(basement membrane organization)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032675|interpro:IPR036116|mint:Q8BLU0|rcsb pdb:4V2C|rcsb pdb:4V2D|rcsb pdb:5FTT|rcsb pdb:5FTU|reactome:R-MMU-5654687|interpro:IPR001611(Leucine-rich repeat)|dip:DIP-61401N|refseq:NP_958926.1|refseq:XP_006516118.1|refseq:XP_011242434.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:gM+zL5eyX55UnQl/Tw/YauTG0FM10090 rigid:WbD9N5NtbJQjts3P63oaXuQ6iis false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:P23116 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-2552342|uniprotkb:E9QQ50|ensembl:ENSMUSP00000025955|uniprotkb:Q62162|uniprotkb:Q60697 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:eif3a_mouse(display_long)|uniprotkb:Eif3a(gene name)|psi-mi:Eif3a(display_short)|uniprotkb:Csma(gene name synonym)|uniprotkb:Eif3(gene name synonym)|uniprotkb:Eif3s10(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 10(gene name synonym)|uniprotkb:eIF-3-theta(gene name synonym)|uniprotkb:eIF3 p167(gene name synonym)|uniprotkb:eIF3 p180(gene name synonym)|uniprotkb:eIF3 p185(gene name synonym)|uniprotkb:p162(gene name synonym)|uniprotkb:Centrosomin(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287669|imex:IM-26899-295 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 ensembl:ENSMUSG00000024991(gene)|ensembl:ENSMUST00000025955(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002188"(translation reinitiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0005874"(microtubule)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071540"(eukaryotic translation initiation factor 3 complex, eIF3e)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR027512|mint:P23116|reactome:R-MMU-156827|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|go:"GO:0014069"(postsynaptic density)|refseq:NP_034253.3 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:oL2Xlz5tghN0YkjvCd3nXOj15Hk10090 rigid:71wQSGK4X6jUMs9m86s4wIKbCX0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:P63037 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-772408|uniprotkb:P54102|ensembl:ENSMUSP00000030118|ensembl:ENSMUSP00000129730 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:dnja1_mouse(display_long)|uniprotkb:Heat shock 40 kDa protein 4(gene name synonym)|uniprotkb:DnaJ protein homolog 2(gene name synonym)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:Dnaja1(gene name)|psi-mi:Dnaja1(display_short)|uniprotkb:Dnaj2(gene name synonym)|uniprotkb:Hsj2(gene name synonym)|uniprotkb:Hspf4(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287663|imex:IM-26899-525 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 refseq:NP_001158143.1|refseq:NP_001158144.1|refseq:NP_032324.1|dip:DIP-32350N|ensembl:ENSMUSG00000028410(gene)|ensembl:ENSMUST00000030118(transcript)|ensembl:ENSMUST00000164233(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009408"(response to heat)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:1901998"(toxin transport)|go:"GO:1903748"(negative regulation of establishment of protein localization to mitochondrion)|go:"GO:1905259"(negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:P63037|reactome:R-MMU-3371497 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:gi42F7LF6CiylXZF4fRg/kuM/s010090 rigid:zqxuLsO7ypyp5loj/A2BQJxF2qg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3TDX8 uniprotkb:Q83B01 intact:EBI-7928047|uniprotkb:Q6VXY4|uniprotkb:Q8BTI5|uniprotkb:Q3U012|uniprotkb:Q8BJV8|intact:UNK-5537179|uniprotkb:Q3TJH3|uniprotkb:Q6VXY5|uniprotkb:E9Q129|uniprotkb:Q8R3H8|uniprotkb:Q99LY4|uniprotkb:Q99P29|ensembl:ENSMUSP00000126119 intact:EBI-21286307|ensemblbacteria:AAO91219 psi-mi:nb5r4_mouse(display_long)|uniprotkb:Cyb5r4(gene name)|psi-mi:Cyb5r4(display_short)|uniprotkb:Ncb5or(gene name synonym)|uniprotkb:Flavohemoprotein b5/b5R(gene name synonym)|uniprotkb:cb5/cb5R(gene name synonym)|uniprotkb:N-terminal cytochrome b5 and cytochrome b5 oxidoreductase domain-containing protein(gene name synonym) psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287657|imex:IM-26899-523 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077157.2|refseq:XP_006511262.1|ensembl:ENSMUSG00000032872(gene)|ensembl:ENSMUST00000168529(transcript)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0004128"("cytochrome-b5 reductase activity, acting on NAD(P)H")|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006739"(NADP metabolic process)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016653"("oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor")|go:"GO:0020037"(heme binding)|interpro:IPR001199(Cytochrome b5)|go:"GO:0030073"(insulin secretion)|go:"GO:0042168"(heme metabolic process)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0046677"(response to antibiotic)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001834("NADH:cytochrome b5 reductase (CBR)")|interpro:IPR007052(CS domain)|interpro:IPR008333(Oxidoreductase FAD-binding region)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR017927|interpro:IPR017938|interpro:IPR018506|interpro:IPR036400|interpro:IPR037908|interpro:IPR039261|mint:Q3TDX8|reactome:R-MMU-1237044|go:"GO:0046872"(metal ion binding)|go:"GO:0048468"(cell development)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0072593"(reactive oxygen species metabolic process) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 - comment:mint|function:"NADH-cytochrome b5 reductase involved in endolasmic reticulum stress response pathway. Plays a critical role in protecting pancreatic beta-cells against oxidant stress, possibly by protecting the cell from excess buildup of reactive oxygen species (ROS)" - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:j19wK584v3ZVxPwALGRiJ1DnnvU10090 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rigid:YHELBtRCNJ306pLhTYkfsHzucVM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:Q9QXK3 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-21287612|ensembl:ENSMUSP00000038368|uniprotkb:A6H6J5|uniprotkb:Q3TQD5|uniprotkb:Q3UEL6|uniprotkb:Q8C2J6 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:copg2_mouse(display_long)|uniprotkb:Copg2(gene name)|psi-mi:Copg2(display_short)|uniprotkb:Gamma-2-coat protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287651|imex:IM-26899-81 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 ensembl:ENSMUSG00000025607(gene)|ensembl:ENSMUST00000048774(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0009306"(protein secretion)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030426"(growth cone)|go:"GO:0072384"(organelle transport along microtubule)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013040(Coatomer, gamma subunit, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017106(Coatomer, gamma subunit)|interpro:IPR032154|interpro:IPR037067|mint:Q9QXK3|reactome:R-MMU-6807878|reactome:R-MMU-6811434|refseq:NP_059506.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:DEQGirBT9URbx4HIfXTFHtAFjm410090 rigid:53FEgIl08DtBsKRjqwu69JcGV/Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:Q8K2G4 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-2892924|ensembl:ENSMUSP00000103791|uniprotkb:Q8C7G3|uniprotkb:Q8CH00|uniprotkb:Q9CXC2 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:bbs7_mouse(display_long)|uniprotkb:Bbs7(gene name)|psi-mi:Bbs7(display_short)|uniprotkb:Bbs2l1(gene name synonym)|uniprotkb:BBS2-like protein 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287606|imex:IM-26899-293 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 ensembl:ENSMUSG00000037325(gene)|ensembl:ENSMUST00000108156(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005930"(axoneme)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034464"(BBSome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043005"(neuron projection)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0046907"(intracellular transport)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060173"(limb development)|go:"GO:0060271"(cilium assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1903929"(primary palate development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR016575(Bardet-Biedl syndrome 7 protein)|interpro:IPR036322|mint:Q8K2G4|reactome:R-MMU-5620922|go:"GO:0007224"(smoothened signaling pathway)|refseq:NP_082086.2|dip:DIP-60353N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:7StHJMzhLoqoT+8pRQuNHTdRVW810090 rigid:Jh+hYSHkIgjgesLDc9Z9y0idZ3Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:P28658 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-4284019|uniprotkb:Q543S3|uniprotkb:Q99LP5|uniprotkb:Q9D1I1|ensembl:ENSMUSP00000132450 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:atx10_mouse(display_long)|uniprotkb:Atxn10(gene name)|psi-mi:Atxn10(display_short)|uniprotkb:Sca10(gene name synonym)|uniprotkb:Brain protein E46(gene name synonym)|uniprotkb:Spinocerebellar ataxia type 10 protein homolog(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287600|imex:IM-26899-189 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 refseq:NP_058539.2|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060271"(cilium assembly)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019156|mint:P28658|go:"GO:0042802"(identical protein binding)|ensembl:ENSMUSG00000016541(gene)|ensembl:ENSMUST00000163242(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development) - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:cxYVinpnTlmg90CtHSELPioHT6s10090 rigid:XoWaayH/JgzZ9GEniNNDhn8XIHs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:E9PZJ8 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-6908800|ensembl:ENSMUSP00000036726|uniprotkb:Q6PB36|uniprotkb:Q8C1G1|uniprotkb:Q8C707|uniprotkb:Q8K292 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:ascc3_mouse(display_long)|uniprotkb:Ascc3(gene name)|psi-mi:Ascc3(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287582|imex:IM-26899-619 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 ensembl:ENSMUSG00000038774(gene)|ensembl:ENSMUST00000035606(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006307"(DNA dealkylation involved in DNA repair)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0099053"(activating signal cointegrator 1 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|mint:E9PZJ8|refseq:NP_932124.2 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:3I/JnJBenvV+YpjqxIwbfPEK9WA10090 rigid:/vT67HWUxsPKPnV1/WCfXIYJUYY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83AQ5 uniprotkb:P83741 intact:EBI-21288048|ensemblbacteria:AAO91318 intact:EBI-21287968|ensembl:ENSMUSP00000063001|uniprotkb:A6H6V1|uniprotkb:B2RRJ7|uniprotkb:B7ZNJ4|uniprotkb:Q3UZP3|uniprotkb:Q6A083|uniprotkb:Q6IFS6|uniprotkb:Q6VYA0 psi-mi:q83aq5_coxbu(display_long)|uniprotkb:CBU_1825(locus name) psi-mi:wnk1_mouse(display_long)|uniprotkb:Wnk1(gene name)|psi-mi:Wnk1(display_short)|uniprotkb:Hsn2(gene name synonym)|uniprotkb:Prkwnk1(gene name synonym)|uniprotkb:Protein kinase lysine-deficient 1(gene name synonym)|uniprotkb:Protein kinase with no lysine 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288054|imex:IM-26899-193 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91318(transcript)|ensemblbacteria:CBU_1825(gene)|refseq:NP_820804.1|refseq:WP_005772185.1|mint:Q83AQ5 ensembl:ENSMUSG00000045962(gene)|ensembl:ENSMUST00000060043(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0003084"(positive regulation of systemic arterial blood pressure)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006811"(ion transport)|go:"GO:0007165"(signal transduction)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033633"(negative regulation of cell-cell adhesion mediated by integrin)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038116"("chemokine (C-C motif) ligand 21 signaling pathway")|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050794"(regulation of cellular process)|go:"GO:0050801"(ion homeostasis)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0090188"(negative regulation of pancreatic juice secretion)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097022"(lymphocyte migration into lymph node)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903038"(negative regulation of leukocyte cell-cell adhesion)|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1904062"(regulation of cation transmembrane transport)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR024678|mint:P83741|reactome:R-MMU-2672351|refseq:NP_001171949.1|refseq:NP_001171950.1|refseq:NP_001186012.1|refseq:NP_001186013.1|refseq:NP_941992.2|refseq:XP_017177038.1|refseq:XP_017177043.1|refseq:XP_017177046.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:f/YqKUKMCtz2fF8sAqFORVGRmY8227377 rogid:r7Vo5Os7OE8aMR0kvHTibK3z4ww10090 rigid:fwZ5LaJB+FfiSjcmkKdUV60OKwY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:P30730 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-21287687|ensembl:ENSMUSP00000024916 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:lshr_mouse(display_long)|uniprotkb:Lhcgr(gene name)|psi-mi:Lhcgr(display_short)|uniprotkb:Lhr(gene name synonym)|uniprotkb:Luteinizing hormone receptor(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287750|imex:IM-26899-803 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 ensembl:ENSMUSG00000024107(gene)|ensembl:ENSMUST00000024916(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0004964"(luteinizing hormone receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0008584"(male gonad development)|go:"GO:0008585"(female gonad development)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0017046"(peptide hormone binding)|go:"GO:0022602"(ovulation cycle process)|go:"GO:0031233"(intrinsic component of external side of plasma membrane)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0034699"(response to luteinizing hormone)|go:"GO:0035472"(choriogonadotropin hormone receptor activity)|go:"GO:0038106"(choriogonadotropin hormone binding)|go:"GO:0042700"(luteinizing hormone signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043235"(receptor complex)|go:"GO:0046544"(development of secondary male sexual characteristics)|go:"GO:0046886"(positive regulation of hormone biosynthetic process)|go:"GO:0050482"(arachidonic acid secretion)|go:"GO:0050850"(positive regulation of calcium-mediated signaling)|go:"GO:0050890"(cognition)|go:"GO:0051117"(ATPase binding)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0060065"(uterus development)|go:"GO:0071371"(cellular response to gonadotropin stimulus)|go:"GO:0071373"(cellular response to luteinizing hormone stimulus)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0090030"(regulation of steroid hormone biosynthetic process)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002131(Glycoprotein hormone receptor)|interpro:IPR002273(Lutropin-choriogonadotropic hormone receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR026906|interpro:IPR032675|mint:P30730|reactome:R-MMU-375281|reactome:R-MMU-418555|refseq:NP_038610.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:3RR+U1NQMHXeh2aL2AZjxL7iaWw10090 rigid:9C8/FrNQRW1klC7+DbHsZBKpckw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83AX6 uniprotkb:P26443 intact:EBI-21287950|ensemblbacteria:AAO91245 intact:EBI-773329|uniprotkb:Q8C273|ensembl:ENSMUSP00000022322 psi-mi:q83ax6_coxbu(display_long)|uniprotkb:CBU_1751(locus name) psi-mi:dhe3_mouse(display_long)|uniprotkb:Glud1(gene name)|psi-mi:Glud1(display_short)|uniprotkb:Glud(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287956|imex:IM-26899-89 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91245(transcript)|ensemblbacteria:CBU_1751(gene)|refseq:NP_820731.1|refseq:WP_010958415.1|mint:Q83AX6 refseq:NP_032159.1|ensembl:ENSMUSG00000021794(gene)|ensembl:ENSMUST00000022322(transcript)|go:"GO:0004352"("glutamate dehydrogenase (NAD+) activity")|go:"GO:0004353"("glutamate dehydrogenase [NAD(P)+] activity")|go:"GO:0004354"("glutamate dehydrogenase (NADP+) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006537"(glutamate biosynthetic process)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0007616"(long-term memory)|go:"GO:0010044"(response to aluminum ion)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0043531"(ADP binding)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070728"(leucine binding)|go:"GO:0072350"(tricarboxylic acid metabolic process)|interpro:IPR006095(Glutamate/phenylalanine/leucine/valine dehydrogenase)|interpro:IPR006096(Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal)|interpro:IPR006097(Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation region)|interpro:IPR033524|interpro:IPR033922|interpro:IPR036291|mint:P26443|reactome:R-MMU-2151201|reactome:R-MMU-8964539 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:5DOBkkrnsv5/6qgMVb3tB83dLnU227377 rogid:HbPeUm/tpMD6GrgM/863swTQqGA10090 rigid:4pLvFSNFRco/AE85fofVWW+ymI8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:Q9ERF3 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-6094557|uniprotkb:Q3U562|uniprotkb:Q9CZP1|ensembl:ENSMUSP00000056359|ensembl:ENSMUSP00000113560 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:wdr61_mouse(display_long)|uniprotkb:Wdr61(gene name)|psi-mi:Wdr61(display_short)|uniprotkb:Meiotic recombination REC14 protein homolog(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287944|imex:IM-26899-87 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 refseq:NP_001020546.1|refseq:NP_075680.1|ensembl:ENSMUSG00000061559(gene)|ensembl:ENSMUST00000051822(transcript)|ensembl:ENSMUST00000121204(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0055087"(Ski complex)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9ERF3|reactome:R-MMU-112382|reactome:R-MMU-429958|reactome:R-MMU-674695|reactome:R-MMU-75955|reactome:R-MMU-8866654 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:r5TxJiuiFNk5dUDuhzCqFfFXX/M10090 rigid:FuGqbP+ER1YO1TAXVe6D3HuaJtw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:Q9D2M8 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-911251|uniprotkb:Q8BGH6|uniprotkb:Q8CE99|uniprotkb:Q8K2V7|uniprotkb:Q9CYD7|uniprotkb:Q9ERI8|uniprotkb:A6X924|ensembl:ENSMUSP00000111443 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:ub2v2_mouse(display_long)|uniprotkb:Ubc-like protein MMS2(gene name synonym)|uniprotkb:Ube2v2(gene name)|psi-mi:Ube2v2(display_short)|uniprotkb:Mms2(gene name synonym)|uniprotkb:Uev2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287938|imex:IM-26899-715 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 refseq:NP_001152823.1|refseq:NP_076074.2|ensembl:ENSMUSG00000022674(gene)|ensembl:ENSMUST00000115777(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006301"(postreplication repair)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042275"(error-free postreplication DNA repair)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q9D2M8|reactome:R-MMU-5693565|reactome:R-MMU-5693571|reactome:R-MMU-5693607|reactome:R-MMU-5696395|reactome:R-MMU-69473|reactome:R-MMU-8866654|reactome:R-MMU-983168 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:nY0ENcwjbooLvqOoe1NdM4Dp4J410090 rigid:eqF4XF1wc0BF809DtOPGFIH9Mh4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P07309 uniprotkb:Q83B01 intact:EBI-8345356|intact:MINT-1855774|ensembl:ENSMUSP00000074783 intact:EBI-21286307|ensemblbacteria:AAO91219 psi-mi:tthy_mouse(display_long)|uniprotkb:Ttr(gene name)|psi-mi:Ttr(display_short)|uniprotkb:Prealbumin(gene name synonym) psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287932|imex:IM-26899-805 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_038725.1|dip:DIP-29726N|ensembl:ENSMUSG00000061808(gene)|ensembl:ENSMUST00000075312(transcript)|go:"GO:0005179"(hormone activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006144"(purine nucleobase metabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042562"(hormone binding)|go:"GO:0042572"(retinol metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070324"(thyroid hormone binding)|go:"GO:0070327"(thyroid hormone transport)|interpro:IPR000895(Transthyretin)|interpro:IPR023416|interpro:IPR023418|interpro:IPR023419|interpro:IPR030178|interpro:IPR036817|mint:P07309|rcsb pdb:2QPF|reactome:R-MMU-2453902|reactome:R-MMU-3000171|reactome:R-MMU-6798695|reactome:R-MMU-975634 ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 - comment:mint|function:Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:hkkz23yVTIqCYtItyjSDzZabauw10090 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rigid:i+ONRSBxgUojCQLV9zwf9Or6sCQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:Q9D7L8 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-21287900|ensembl:ENSMUSP00000072427|ensembl:ENSMUSP00000099553|uniprotkb:Q8R202 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:tmig1_mouse(display_long)|uniprotkb:Tmigd1(gene name)|psi-mi:Tmigd1(display_short)|uniprotkb:Tmigd(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287926|imex:IM-26899-425 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:Q9D7L8|ensembl:ENSMUSG00000020839(gene)|ensembl:ENSMUST00000072633(transcript)|ensembl:ENSMUST00000102495(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0090559"(regulation of membrane permeability)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|refseq:NP_079931.1|refseq:XP_006534010.2|refseq:XP_006534013.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:uz4+xnAe8J5epbh3g3l7i7JO8pQ10090 rigid:PBfwv8sX2LQF88o6usOGsfVjMWg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:A2AGL3 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-9663179|uniprotkb:P70184|uniprotkb:P70185|uniprotkb:Q3V1H0|uniprotkb:Q4JFC4|uniprotkb:Q60836|uniprotkb:Q62175|uniprotkb:Q62198|uniprotkb:Q9QY91|ensembl:ENSMUSP00000079503 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:ryr3_mouse(display_long)|uniprotkb:Ryr3(gene name)|psi-mi:Ryr3(display_short)|uniprotkb:Brain ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Brain-type ryanodine receptor(gene name synonym)|uniprotkb:Type 3 ryanodine receptor(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287894|imex:IM-26899-191 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 refseq:XP_017172194.1|ensembl:ENSMUSG00000057378(gene)|ensembl:ENSMUST00000080673(transcript)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030314"(junctional membrane complex)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034704"(calcium channel complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071286"(cellular response to magnesium ion)|go:"GO:0071313"(cellular response to caffeine)|go:"GO:0071318"(cellular response to ATP)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013333(Ryanodine receptor, N-terminal)|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR016093(MIR motif)|interpro:IPR035761|interpro:IPR035762|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:A2AGL3|reactome:R-MMU-2672351|reactome:R-MMU-5578775 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:w+H5SoOQ5mY1oZo1nGFxnYlehlY10090 rigid:zctZSbmG7HURTqufSlux074aQKc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BML9 uniprotkb:Q83B01 intact:EBI-8419150|intact:MINT-4111591|uniprotkb:Q3TN94|uniprotkb:Q8BU21|ensembl:ENSMUSP00000006838 intact:EBI-21286307|ensemblbacteria:AAO91219 psi-mi:syq_mouse(display_long)|uniprotkb:Qars1(gene name)|psi-mi:Qars1(display_short)|uniprotkb:Glutaminyl-tRNA synthetase(gene name synonym)|uniprotkb:Qars(gene name synonym) psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287888|imex:IM-26899-85 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_598555.2|ensembl:ENSMUSG00000032604(gene)|ensembl:ENSMUST00000006838(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004819"(glutamine-tRNA ligase activity)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006425"(glutaminyl-tRNA aminoacylation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007420"(brain development)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000924(Glutamyl/glutaminyl-tRNA synthetase, class Ic)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR004514(Glutaminyl-tRNA synthetase, class Ic)|interpro:IPR007638(Glutaminyl-tRNA synthetase, class Ic, non-specific RNA-binding region part 2)|interpro:IPR007639(Glutaminyl-tRNA synthetase, class Ic, non-specific RNA-binding region part 1)|interpro:IPR011035(Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR020056|interpro:IPR020058|interpro:IPR020059|interpro:IPR042558|interpro:IPR042559|mint:Q8BML9 ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 - comment:mint - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:hrTtEXyR3ahEOAvjQfJWhLryWFM10090 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rigid:SxVGRDDQtsLre68iGdoq33+jpns false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:Q922H1 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-5237469|uniprotkb:Q80VU9|uniprotkb:Q8BFV5 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:anm3_mouse(display_long)|uniprotkb:Prmt3(gene name)|psi-mi:Prmt3(display_short)|uniprotkb:Hrmt1l3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287882|imex:IM-26899-423 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 refseq:NP_598501.1|interpro:IPR025799|interpro:IPR036236|interpro:IPR029063|mint:Q922H1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0019919"(peptidyl-arginine methylation, to asymmetrical-dimethyl arginine)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0043022"(ribosome binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0072341"(modified amino acid binding)|go:"GO:1900053"(negative regulation of retinoic acid biosynthetic process)|rcsb pdb:1WIR|reactome:R-MMU-3214858|reactome:R-MMU-8876725 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:UUVe45yXYsF2oGGOCeT8IYFgBVk10090 rigid:f3zpo2r7N/X0Edw4J7TzLCYAGfc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:Q3U3W5 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-21287849|ensembl:ENSMUSP00000112692|uniprotkb:D3YU52|uniprotkb:Q8BLF8|uniprotkb:Q8BLG1 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:anm9_mouse(display_long)|uniprotkb:Prmt9(gene name)|psi-mi:Prmt9(display_short)|uniprotkb:Prmt10(gene name synonym)|uniprotkb:Protein arginine N-methyltransferase 10(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287876|imex:IM-26899-299 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 ensembl:ENSMUSG00000037134(gene)|ensembl:ENSMUST00000118622(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0035243"(protein-arginine omega-N symmetric methyltransferase activity)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR025799|interpro:IPR029063|mint:Q3U3W5|refseq:NP_001074709.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:mz3TPH9s3LesAikDRJ49fxq1N6w10090 rigid:uehYPHKLVJCRpkYWYfF1RCKWK0w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:Q8R1Z4 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-21287305|ensembl:ENSMUSP00000027049|uniprotkb:Q9D5M1|uniprotkb:Q9DAF9 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:ppr42_mouse(display_long)|uniprotkb:Ppp1r42(gene name)|psi-mi:Ppp1r42(display_short)|uniprotkb:Lrrc67(gene name synonym)|uniprotkb:Leucine-rich repeat-containing protein 67(gene name synonym)|uniprotkb:Testis leucine-rich repeat protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287843|imex:IM-26899-531 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 ensembl:ENSMUSG00000025916(gene)|ensembl:ENSMUST00000027049(transcript)|go:"GO:0002177"(manchette)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0010921"(regulation of phosphatase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0070840"(dynein complex binding)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR025875|interpro:IPR032675|mint:Q8R1Z4|refseq:NP_663730.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:OEuz7C5/7qxHPsKscCe0o0cwhAM10090 rigid:pH8eee1ZRm7nQ1UCHQurQsYPma0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:Q9JJN4 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-21287815|ensembl:ENSMUSP00000099700|uniprotkb:B9EHG5 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:sco2a_mouse(display_long)|uniprotkb:Oxct2a(gene name)|psi-mi:Oxct2a(display_short)|uniprotkb:3-oxoacid CoA-transferase 2A(gene name synonym)|uniprotkb:"Testis-specific succinyl-CoA:3-oxoacid CoA-transferase 1"(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287837|imex:IM-26899-421 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0008260"(3-oxoacid CoA-transferase activity)|go:"GO:0008410"(CoA-transferase activity)|go:"GO:0046950"(cellular ketone body metabolic process)|go:"GO:0046952"(ketone body catabolic process)|interpro:IPR004163(Coenzyme A transferase binding site)|interpro:IPR004164(Coenzyme A transferase active site)|interpro:IPR004165(Coenzyme A transferase)|interpro:IPR012791(3-oxoacid CoA-transferase, subunit B)|interpro:IPR012792(3-oxoacid CoA-transferase, subunit A)|interpro:IPR014388(3-oxoacid CoA-transferase)|interpro:IPR037171|mint:Q9JJN4|ensembl:ENSMUSG00000076436(gene)|ensembl:ENSMUST00000102640(transcript)|go:"GO:0005739"(mitochondrion)|refseq:NP_071316.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:MYuL2D1hHi3ql+ccOwNxex3OG9Y10090 rigid:ablTaeHwejZy22Vzznbc9Ckmxd8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:Q7TQI3 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-2309876|uniprotkb:Q3ULV9|uniprotkb:Q3V408|uniprotkb:Q8C326|uniprotkb:Q8R5F2|ensembl:ENSMUSP00000025679 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:otub1_mouse(display_long)|uniprotkb:Otub1(gene name)|psi-mi:Otub1(display_short)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287809|imex:IM-26899-297 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 refseq:NP_598911.1|ensembl:ENSMUSG00000024767(gene)|ensembl:ENSMUST00000025679(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q7TQI3|reactome:R-MMU-5689880|reactome:R-MMU-5689896 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:8wyAgdbYnbsj8QYkhuruP2tdw5Q10090 rigid:1rbEs/vLGRBBh2UP7tSdJvK5XBM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z0J0 uniprotkb:Q83B01 intact:EBI-8408018|intact:MINT-4104065|uniprotkb:Q3UB23|ensembl:ENSMUSP00000021668 intact:EBI-21286307|ensemblbacteria:AAO91219 psi-mi:npc2_mouse(display_long)|uniprotkb:Npc2(gene name)|psi-mi:Npc2(display_short)|uniprotkb:Niemann Pick type C2 protein homolog(gene name synonym)|uniprotkb:Epididymal secretory protein E1(gene name synonym) psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287803|imex:IM-26899-529 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_075898.1|ensembl:ENSMUSG00000021242(gene)|ensembl:ENSMUST00000021668(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015918"(sterol transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0030301"(cholesterol transport)|go:"GO:0032366"(intracellular sterol transport)|go:"GO:0032367"(intracellular cholesterol transport)|go:"GO:0032934"(sterol binding)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR003172(MD-2-related lipid-recognition)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR033916|interpro:IPR039670|mint:Q9Z0J0|reactome:R-MMU-6798695|reactome:R-MMU-8964038 ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 - comment:mint|function:May be involved in the regulation of the lipid composition of sperm membranes during the maturation in the epididymis - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:eDUNxC5PVN2I/spwfEGtuIV7dOI10090 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rigid:kYsuhoPPp5GlfpQX7ThLW8s9Jv0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:Q8CCP0 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-21287768|ensembl:ENSMUSP00000021368|uniprotkb:Q9CW30|uniprotkb:Q3TAS9|uniprotkb:Q3UF46|uniprotkb:Q66JX6|uniprotkb:Q8C9R6|uniprotkb:Q8CA65|uniprotkb:Q8JZT9|uniprotkb:Q8R072|uniprotkb:Q9CYB8|uniprotkb:Q9D4A9 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:nemf_mouse(display_long)|uniprotkb:Nemf(gene name)|psi-mi:Nemf(display_short)|uniprotkb:Sdccag1(gene name synonym)|uniprotkb:Serologically defined colon cancer antigen 1 homolog(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287797|imex:IM-26899-713 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 go:"GO:1990116"(ribosome-associated ubiquitin-dependent protein catabolic process)|interpro:IPR008532(Protein of unknown function DUF814)|interpro:IPR021846|mint:Q8CCP0|ensembl:ENSMUSG00000020982(gene)|ensembl:ENSMUST00000021368(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0051168"(nuclear export)|go:"GO:0072344"(rescue of stalled ribosome)|go:"GO:1990112"(RQC complex)|refseq:NP_079717.2 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:bG5XjTFtIiLOkxsOodoR69nYkcU10090 rigid:SBu4ZpqPissa9CAwKCKyr2FqdQs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7TPH6 uniprotkb:Q83B01 intact:EBI-1811542|uniprotkb:Q6PCM8|uniprotkb:E9PUJ6 intact:EBI-21286307|ensemblbacteria:AAO91219 psi-mi:mycb2_mouse(display_long)|uniprotkb:Mycbp2(gene name)|psi-mi:Mycbp2(display_short)|uniprotkb:Pam(gene name synonym)|uniprotkb:Phr1(gene name synonym)|uniprotkb:Myc-binding protein 2(gene name synonym)|uniprotkb:Protein associated with Myc(gene name synonym)|uniprotkb:Pam/highwire/rpm-1 protein(gene name synonym)|uniprotkb:Protein Magellan(gene name synonym) psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287762|imex:IM-26899-83 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008979(Galactose-binding like)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR012983(PHR)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR001841(Zinc finger, RING-type)|refseq:NP_997098.2|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR017868|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q7TPH6|interpro:IPR038648|interpro:IPR003646(Bacterial SH3-like region)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0021785"(branchiomotor neuron axon guidance)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0030424"(axon)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902667"(regulation of axon guidance)|rcsb pdb:3GBW|rcsb pdb:3HWJ ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:LHdZ193Nhz4e+Iq5+Sua2QwrAWA10090 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rigid:kChh+fvbWXSkkGNvya7eAztcUu8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:Q99MR8 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-773469|uniprotkb:Q3TGU0|uniprotkb:Q9D8R2|ensembl:ENSMUSP00000029259 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:mcca_mouse(display_long)|uniprotkb:3-methylcrotonyl-CoA carboxylase 1(gene name synonym)|uniprotkb:"3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha"(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase biotin-containing subunit(gene name synonym)|uniprotkb:Mccc1(gene name)|psi-mi:Mccc1(display_short)|uniprotkb:Mcca(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287756|imex:IM-26899-527 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 refseq:NP_076133.3|ensembl:ENSMUSG00000027709(gene)|ensembl:ENSMUST00000029259(transcript)|go:"GO:0002169"(3-methylcrotonyl-CoA carboxylase complex, mitochondrial)|go:"GO:0004485"(methylcrotonoyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0016421"(CoA carboxylase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:1905202"(methylcrotonoyl-CoA carboxylase complex)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001882(Biotin-binding site)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR016185(PreATP-grasp-like fold)|mint:Q99MR8|reactome:R-MMU-196780|reactome:R-MMU-70895 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:SziuYdcOx+maKy71pNxoKql1HGI10090 rigid:6sMgrIOK4ftKeLuPvE6m0LVE2rk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83AX6 uniprotkb:P70663 intact:EBI-21287950|ensemblbacteria:AAO91245 intact:EBI-2012890|uniprotkb:E9QPH2|uniprotkb:P97810|uniprotkb:Q99L82|ensembl:ENSMUSP00000031249 psi-mi:q83ax6_coxbu(display_long)|uniprotkb:CBU_1751(locus name) psi-mi:sprl1_mouse(display_long)|uniprotkb:Sparcl1(gene name)|psi-mi:Sparcl1(display_short)|uniprotkb:Ecm2(gene name synonym)|uniprotkb:Sc1(gene name synonym)|uniprotkb:Matrix glycoprotein Sc1(gene name synonym)|uniprotkb:Extracellular matrix protein 2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21287962|imex:IM-26899-627 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91245(transcript)|ensemblbacteria:CBU_1751(gene)|refseq:NP_820731.1|refseq:WP_010958415.1|mint:Q83AX6 refseq:NP_034227.3|refseq:XP_017176145.1|refseq:XP_006534831.1|ensembl:ENSMUSG00000029309(gene)|ensembl:ENSMUST00000031249(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0007165"(signal transduction)|go:"GO:0045202"(synapse)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0098965"(extracellular matrix of synaptic cleft)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099560"(synaptic membrane adhesion)|interpro:IPR001999(Osteonectin-like, conserved site)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR003645(Follistatin-like, N-terminal)|interpro:IPR011992(EF-Hand type)|interpro:IPR015369(Follistatin)|interpro:IPR016359(SPARC-like protein 1)|interpro:IPR018247|interpro:IPR019577|interpro:IPR036058|mint:P70663|reactome:R-MMU-381426|reactome:R-MMU-8957275 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:5DOBkkrnsv5/6qgMVb3tB83dLnU227377 rogid:PdnEQBF1vQqXJM9/Qiz/45+Mdc410090 rigid:agJ+S8+u+OpWklcr59wgG0rLN5k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A54 uniprotkb:P70663 intact:EBI-21288084|ensemblbacteria:AAO91541 intact:EBI-2012890|uniprotkb:E9QPH2|uniprotkb:P97810|uniprotkb:Q99L82|ensembl:ENSMUSP00000031249 psi-mi:q83a54_coxbu(display_long)|uniprotkb:CBU_2056(locus name) psi-mi:sprl1_mouse(display_long)|uniprotkb:Sparcl1(gene name)|psi-mi:Sparcl1(display_short)|uniprotkb:Ecm2(gene name synonym)|uniprotkb:Sc1(gene name synonym)|uniprotkb:Matrix glycoprotein Sc1(gene name synonym)|uniprotkb:Extracellular matrix protein 2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288096|imex:IM-26899-807 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91541(transcript)|ensemblbacteria:CBU_2056(gene)|refseq:NP_821027.2|refseq:WP_010958626.1|mint:Q83A54 refseq:NP_034227.3|refseq:XP_017176145.1|refseq:XP_006534831.1|ensembl:ENSMUSG00000029309(gene)|ensembl:ENSMUST00000031249(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0007165"(signal transduction)|go:"GO:0045202"(synapse)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0098965"(extracellular matrix of synaptic cleft)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099560"(synaptic membrane adhesion)|interpro:IPR001999(Osteonectin-like, conserved site)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR003645(Follistatin-like, N-terminal)|interpro:IPR011992(EF-Hand type)|interpro:IPR015369(Follistatin)|interpro:IPR016359(SPARC-like protein 1)|interpro:IPR018247|interpro:IPR019577|interpro:IPR036058|mint:P70663|reactome:R-MMU-381426|reactome:R-MMU-8957275 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:7M6Io5lFM04euaFbtNKHnNLhJcQ227377 rogid:PdnEQBF1vQqXJM9/Qiz/45+Mdc410090 rigid:dEl9vrDUz82L7NlKF1CicoiPaWI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A54 uniprotkb:Q9QZQ8 intact:EBI-21288084|ensemblbacteria:AAO91541 intact:EBI-3508334|uniprotkb:Q91VZ2|uniprotkb:Q9QZQ7|ensembl:ENSMUSP00000016081 psi-mi:q83a54_coxbu(display_long)|uniprotkb:CBU_2056(locus name) psi-mi:h2ay_mouse(display_long)|uniprotkb:Macroh2a1(gene name)|psi-mi:Macroh2a1(display_short)|uniprotkb:H2A.y(gene name synonym)|uniprotkb:H2A/y(gene name synonym)|uniprotkb:H2afy(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288090|imex:IM-26899-429 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91541(transcript)|ensemblbacteria:CBU_2056(gene)|refseq:NP_821027.2|refseq:WP_010958626.1|mint:Q83A54 refseq:NP_001152985.1|refseq:NP_001152986.1|refseq:NP_001152987.1|refseq:NP_036145.1|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0001740"(Barr body)|go:"GO:0033128"(negative regulation of histone phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0034184"(positive regulation of maintenance of mitotic sister chromatid cohesion)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:1901837"(negative regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902750"(negative regulation of cell cycle G2/M phase transition)|go:"GO:1902882"(regulation of response to oxidative stress)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:1902883"(negative regulation of response to oxidative stress)|go:"GO:0005730"(nucleolus)|go:"GO:1902884"(positive regulation of response to oxidative stress)|go:"GO:1903226"(positive regulation of endodermal cell differentiation)|go:"GO:1904815"(negative regulation of protein localization to chromosome, telomeric region)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR002119(Histone H2A)|interpro:IPR002589(Appr-1-p processing)|interpro:IPR007125(Histone core)|go:"GO:0005813"(centrosome)|interpro:IPR009072(Histone-fold)|interpro:IPR021171|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|interpro:IPR032454|go:"GO:0007549"(dosage compensation)|interpro:IPR035796|interpro:IPR043472|mint:Q9QZQ8|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0019216"(regulation of lipid metabolic process)|ensembl:ENSMUSG00000015937(gene)|ensembl:ENSMUST00000016081(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000182"(rDNA binding)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding) - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:7M6Io5lFM04euaFbtNKHnNLhJcQ227377 rogid:70q7YQGYxyE7ZBq8e7oOsIUSY0810090 rigid:yKKzOL03LBALO1hH5RXMUuKlS8o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99LC5 uniprotkb:Q83AQ5 intact:EBI-8334254|uniprotkb:Q8BMD3|intact:MINT-1859759|uniprotkb:Q4V9X5|uniprotkb:Q3THD7|uniprotkb:Q8BMU7|uniprotkb:Q3V000|ensembl:ENSMUSP00000034866 intact:EBI-21288048|ensemblbacteria:AAO91318 psi-mi:etfa_mouse(display_long)|uniprotkb:Etfa(gene name)|psi-mi:Etfa(display_short) psi-mi:q83aq5_coxbu(display_long)|uniprotkb:CBU_1825(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288060|imex:IM-26899-629 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_663590.3|ensembl:ENSMUSG00000032314(gene)|ensembl:ENSMUST00000034866(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0017133"(mitochondrial electron transfer flavoprotein complex)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR001308(Electron transfer flavoprotein, alpha subunit)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR014730(Electron transfer flavoprotein, alpha/beta-subunit, N-terminal)|interpro:IPR014731(Electron transfer flavoprotein, alpha subunit, C-terminal)|interpro:IPR018206|interpro:IPR029035|interpro:IPR033947|mint:Q99LC5|reactome:R-MMU-611105 ensemblbacteria:AAO91318(transcript)|ensemblbacteria:CBU_1825(gene)|refseq:NP_820804.1|refseq:WP_005772185.1|mint:Q83AQ5 - comment:mint|function:"The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase)" - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:J1V6KKCCnRXkfr72ArCLeyh9FLg10090 rogid:f/YqKUKMCtz2fF8sAqFORVGRmY8227377 rigid:cvkOwou7PXjmERSxJt2WFJUFfhk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83AQ5 uniprotkb:O88967 intact:EBI-21288048|ensemblbacteria:AAO91318 intact:EBI-11518380|uniprotkb:Q7TNN5|ensembl:ENSMUSP00000028117 psi-mi:q83aq5_coxbu(display_long)|uniprotkb:CBU_1825(locus name) psi-mi:ymel1_mouse(display_long)|uniprotkb:ATP-dependent metalloprotease FtsH1(gene name synonym)|uniprotkb:YME1-like protein 1(gene name synonym)|uniprotkb:Yme1l1(gene name)|psi-mi:Yme1l1(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288072|imex:IM-26899-427 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91318(transcript)|ensemblbacteria:CBU_1825(gene)|refseq:NP_820804.1|refseq:WP_005772185.1|mint:Q83AQ5 refseq:NP_038799.1|ensembl:ENSMUSG00000026775(gene)|ensembl:ENSMUST00000028117(transcript)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0034214"(protein hexamerization)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0035694"(mitochondrial protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000642(Peptidase M41)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005936(Peptidase M41, FtsH)|interpro:IPR027417|interpro:IPR037219|interpro:IPR041569|mint:O88967|reactome:R-MMU-8949664|go:"GO:0007005"(mitochondrion organization) - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:f/YqKUKMCtz2fF8sAqFORVGRmY8227377 rogid:r9+ZzXnqp1squdeZ4KAr6YVU29c10090 rigid:aFKovIB7Bez6clMElKXZdLpD1Xw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9CZG3 uniprotkb:Q83AQ5 intact:EBI-8401809|intact:MINT-4091514|uniprotkb:Q9D7F6|ensembl:ENSMUSP00000013693 intact:EBI-21288048|ensemblbacteria:AAO91318 psi-mi:comd8_mouse(display_long)|uniprotkb:Commd8(gene name)|psi-mi:Commd8(display_short) psi-mi:q83aq5_coxbu(display_long)|uniprotkb:CBU_1825(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288066|imex:IM-26899-305 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_848714.1|ensembl:ENSMUSG00000029213(gene)|ensembl:ENSMUST00000013693(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR017920|mint:Q9CZG3|reactome:R-MMU-8951664 ensemblbacteria:AAO91318(transcript)|ensemblbacteria:CBU_1825(gene)|refseq:NP_820804.1|refseq:WP_005772185.1|mint:Q83AQ5 - comment:mint - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:LmOT5RV1qbX9vjh2+Np9BZJvXKQ10090 rogid:f/YqKUKMCtz2fF8sAqFORVGRmY8227377 rigid:Dqc7qJLH3bIlzv0LiNXMTL6IXvE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O70252 uniprotkb:Q83AQ5 intact:EBI-8327658|uniprotkb:O70626|intact:MINT-1847819|ensembl:ENSMUSP00000004172|ensembl:ENSMUSP00000112397|ensembl:ENSMUSP00000113110 intact:EBI-21288048|ensemblbacteria:AAO91318 psi-mi:hmox2_mouse(display_long)|uniprotkb:Hmox2(gene name)|psi-mi:Hmox2(display_short) psi-mi:q83aq5_coxbu(display_long)|uniprotkb:CBU_1825(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288078|imex:IM-26899-533 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034573.2|refseq:NP_001129538.1|ensembl:ENSMUSG00000004070(gene)|ensembl:ENSMUST00000004172(transcript)|ensembl:ENSMUST00000118885(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004392"("heme oxygenase (decyclizing) activity")|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006788"(heme oxidation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0020037"(heme binding)|go:"GO:0042167"(heme catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR002051(Haem oxygenase)|interpro:IPR016053(Haem oxygenase-like)|interpro:IPR016084(Haem oxygenase-like, multi-helical)|interpro:IPR018207|mint:O70252|reactome:R-MMU-189483|reactome:R-MMU-6798695|reactome:R-MMU-8980692|reactome:R-MMU-917937|reactome:R-MMU-9707564|ensembl:ENSMUST00000120232(transcript) ensemblbacteria:AAO91318(transcript)|ensemblbacteria:CBU_1825(gene)|refseq:NP_820804.1|refseq:WP_005772185.1|mint:Q83AQ5 - function:Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter|comment:mint - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:yovjBQSbWrevBMLIrt6FWdQIY/Y10090 rogid:f/YqKUKMCtz2fF8sAqFORVGRmY8227377 rigid:jwNv1oNRI7d4YDl++FRdA2601vg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A33 uniprotkb:Q9QZQ8 intact:EBI-21286457|ensemblbacteria:AAO91562 intact:EBI-3508334|uniprotkb:Q91VZ2|uniprotkb:Q9QZQ7|ensembl:ENSMUSP00000016081 psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:h2ay_mouse(display_long)|uniprotkb:Macroh2a1(gene name)|psi-mi:Macroh2a1(display_short)|uniprotkb:H2A.y(gene name synonym)|uniprotkb:H2A/y(gene name synonym)|uniprotkb:H2afy(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288156|imex:IM-26899-811 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 refseq:NP_001152985.1|refseq:NP_001152986.1|refseq:NP_001152987.1|refseq:NP_036145.1|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0001740"(Barr body)|go:"GO:0033128"(negative regulation of histone phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0034184"(positive regulation of maintenance of mitotic sister chromatid cohesion)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:1901837"(negative regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902750"(negative regulation of cell cycle G2/M phase transition)|go:"GO:1902882"(regulation of response to oxidative stress)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:1902883"(negative regulation of response to oxidative stress)|go:"GO:0005730"(nucleolus)|go:"GO:1902884"(positive regulation of response to oxidative stress)|go:"GO:1903226"(positive regulation of endodermal cell differentiation)|go:"GO:1904815"(negative regulation of protein localization to chromosome, telomeric region)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR002119(Histone H2A)|interpro:IPR002589(Appr-1-p processing)|interpro:IPR007125(Histone core)|go:"GO:0005813"(centrosome)|interpro:IPR009072(Histone-fold)|interpro:IPR021171|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|interpro:IPR032454|go:"GO:0007549"(dosage compensation)|interpro:IPR035796|interpro:IPR043472|mint:Q9QZQ8|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0019216"(regulation of lipid metabolic process)|ensembl:ENSMUSG00000015937(gene)|ensembl:ENSMUST00000016081(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000182"(rDNA binding)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding) - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rogid:70q7YQGYxyE7ZBq8e7oOsIUSY0810090 rigid:4l2Vgzn1zYYPJcbsm6t9v0J6g98 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A33 uniprotkb:Q9WUA2 intact:EBI-21286457|ensemblbacteria:AAO91562 intact:EBI-11707271|uniprotkb:Q9CWZ8|ensembl:ENSMUSP00000069508|ensembl:ENSMUSP00000129828 psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:syfb_mouse(display_long)|uniprotkb:Farsb(gene name)|psi-mi:Farsb(display_short)|uniprotkb:Farsl(gene name synonym)|uniprotkb:Farslb(gene name synonym)|uniprotkb:Frsb(gene name synonym)|uniprotkb:Phenylalanyl-tRNA synthetase beta subunit(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288150|imex:IM-26899-309 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 refseq:NP_001265004.1|refseq:NP_035941.2|ensembl:ENSMUSG00000026245(gene)|ensembl:ENSMUST00000068333(transcript)|ensembl:ENSMUST00000170217(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|go:"GO:0009328"(phenylalanine-tRNA ligase complex)|go:"GO:0051290"(protein heterotetramerization)|interpro:IPR004531(Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic)|interpro:IPR005146(B3/B4 tRNA-binding domain)|interpro:IPR005147(tRNA synthetase, B5)|interpro:IPR009061(Putative DNA binding)|interpro:IPR020825|interpro:IPR040659|mint:Q9WUA2|interpro:IPR041616 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rogid:qdABVIohiIx9CxsmlBUUYXMkRh810090 rigid:6Cn8JIzyHUppL0eu4m5I/NbQzyY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A33 uniprotkb:Q9D832 intact:EBI-21286457|ensemblbacteria:AAO91562 intact:EBI-4285818|uniprotkb:Q9D9U2|uniprotkb:Q3TS92|ensembl:ENSMUSP00000029669|ensembl:ENSMUSP00000053916|ensembl:ENSMUSP00000114356 psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:dnjb4_mouse(display_long)|uniprotkb:Dnajb4(gene name)|psi-mi:Dnajb4(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288144|imex:IM-26899-809 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 ensembl:ENSMUSG00000028035(gene)|ensembl:ENSMUST00000029669(transcript)|ensembl:ENSMUST00000050073(transcript)|ensembl:ENSMUST00000144950(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:Q9D832|refseq:NP_080202.1|refseq:NP_081563.2|refseq:XP_006501983.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rogid:7vvyn2D5dI3mKW5efpnhChyyazQ10090 rigid:JVWakdlEGTPe8DOrERMucTmITyg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A33 uniprotkb:Q9QYJ0 intact:EBI-21286457|ensemblbacteria:AAO91562 intact:EBI-772431|ensembl:ENSMUSP00000034138 psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:dnja2_mouse(display_long)|uniprotkb:Dnaja2(gene name)|psi-mi:Dnaja2(display_short)|uniprotkb:mDj3(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288138|imex:IM-26899-197 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 refseq:NP_062768.1|ensembl:ENSMUSG00000031701(gene)|ensembl:ENSMUST00000034138(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042026"(protein refolding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:Q9QYJ0|reactome:R-MMU-3371497 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rogid:ZYn3t1WpFrPa82gsMHxjaQRPr3k10090 rigid:6PjRZr7eqo8pnJcBycbvyLbysSI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A54 uniprotkb:Q5SV77 intact:EBI-21288084|ensemblbacteria:AAO91541 intact:EBI-4370069|uniprotkb:A4QPD5|uniprotkb:B7ZP33|uniprotkb:Q5SV75|uniprotkb:Q5SV76|uniprotkb:Q5SV78|uniprotkb:Q6GVH6|uniprotkb:Q6P9J4|uniprotkb:Q920N4|ensembl:ENSMUSP00000117482|ensembl:ENSMUSP00000130013 psi-mi:q83a54_coxbu(display_long)|uniprotkb:CBU_2056(locus name) psi-mi:ggnb2_mouse(display_long)|uniprotkb:Ggnbp2(gene name)|psi-mi:Ggnbp2(display_short)|uniprotkb:Zfp403(gene name synonym)|uniprotkb:Znf403(gene name synonym)|uniprotkb:Dioxin-inducible factor 3(gene name synonym)|uniprotkb:Protein ZNF403(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288102|imex:IM-26899-307 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91541(transcript)|ensemblbacteria:CBU_2056(gene)|refseq:NP_821027.2|refseq:WP_010958626.1|mint:Q83A54 refseq:XP_011247235.1|refseq:NP_694784.2|refseq:XP_017169962.1|refseq:XP_017169963.1|refseq:XP_017169964.1|ensembl:ENSMUSG00000020530(gene)|ensembl:ENSMUST00000154915(transcript)|ensembl:ENSMUST00000168434(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033140"(negative regulation of peptidyl-serine phosphorylation of STAT protein)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0060711"(labyrinthine layer development)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0005737"(cytoplasm)|go:"GO:0007283"(spermatogenesis)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|interpro:IPR026073|mint:Q5SV77|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030154"(cell differentiation) - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:7M6Io5lFM04euaFbtNKHnNLhJcQ227377 rogid:EQsj5CV4B3EETKKqygHDgjuY7Sg10090 rigid:YRhASr24oNR+nAXRdXyrHOoFvQo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A33 uniprotkb:Q9CZ62 intact:EBI-21286457|ensemblbacteria:AAO91562 intact:EBI-648025|uniprotkb:Q8BL35|ensembl:ENSMUSP00000023270 psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:cep97_mouse(display_long)|uniprotkb:Lrriq2(gene name synonym)|uniprotkb:Leucine-rich repeat and IQ domain-containing protein 2(gene name synonym)|uniprotkb:Cep97(gene name)|psi-mi:Cep97(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288126|imex:IM-26899-431 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 refseq:NP_001152836.1|refseq:NP_001152837.1|refseq:NP_001152838.1|refseq:NP_083091.1|ensembl:ENSMUSG00000022604(gene)|ensembl:ENSMUST00000023270(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0030030"(cell projection organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902018"(negative regulation of cilium assembly)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|mint:Q9CZ62|reactome:R-MMU-5620912|reactome:R-MMU-9013424 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rogid:DWiMTuw3lDIkq7+vwiCf3HJZZ7k10090 rigid:wG904MT03ZeRimhCNdH4y1I2VRs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A33 uniprotkb:Q8K019 intact:EBI-21286457|ensemblbacteria:AAO91562 intact:EBI-2536273|uniprotkb:Q8C2E9|uniprotkb:Q9CSW5|uniprotkb:Q8BNZ0|ensembl:ENSMUSP00000043583 psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:bclf1_mouse(display_long)|uniprotkb:Bclaf1(gene name)|psi-mi:Bclaf1(display_short)|uniprotkb:Btf(gene name synonym)|uniprotkb:Kiaa0164(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288120|imex:IM-26899-723 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 ensembl:ENSMUSG00000037608(gene)|ensembl:ENSMUST00000043881(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0016592"(mediator complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043620"(regulation of DNA-templated transcription in response to stress)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR026668|interpro:IPR029199|mint:Q8K019|refseq:NP_001020563.1|refseq:NP_722482.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rogid:+9NQPsUgV77P3yH9iK0ZRDIOioM10090 rigid:7Om1KAmAXYObzNqQ8vh2WSwGxfU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A33 uniprotkb:P28658 intact:EBI-21286457|ensemblbacteria:AAO91562 intact:EBI-4284019|uniprotkb:Q543S3|uniprotkb:Q99LP5|uniprotkb:Q9D1I1|ensembl:ENSMUSP00000132450 psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:atx10_mouse(display_long)|uniprotkb:Atxn10(gene name)|psi-mi:Atxn10(display_short)|uniprotkb:Sca10(gene name synonym)|uniprotkb:Brain protein E46(gene name synonym)|uniprotkb:Spinocerebellar ataxia type 10 protein homolog(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288114|imex:IM-26899-719 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 refseq:NP_058539.2|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060271"(cilium assembly)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019156|mint:P28658|go:"GO:0042802"(identical protein binding)|ensembl:ENSMUSG00000016541(gene)|ensembl:ENSMUST00000163242(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development) - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rogid:cxYVinpnTlmg90CtHSELPioHT6s10090 rigid:moBT+5ynCg4MUxdQu3BLd7s07jM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5XJY5 uniprotkb:Q83A33 intact:EBI-8323149|uniprotkb:Q91W48|intact:MINT-1857447|ensembl:ENSMUSP00000034607 intact:EBI-21286457|ensemblbacteria:AAO91562 psi-mi:copd_mouse(display_long)|uniprotkb:Arcn1(gene name)|psi-mi:Arcn1(display_short)|uniprotkb:Archain(gene name synonym)|uniprotkb:Copd(gene name synonym)|uniprotkb:Delta-coat protein(gene name synonym) psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288108|imex:IM-26899-717 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_666097.3|ensembl:ENSMUSG00000032096(gene)|ensembl:ENSMUST00000034607(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0015031"(protein transport)|go:"GO:0021691"(cerebellar Purkinje cell layer maturation)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0043473"(pigmentation)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0051645"(Golgi localization)|interpro:IPR011012(Longin-like)|interpro:IPR022775|interpro:IPR027059|interpro:IPR028565|interpro:IPR036168|mint:Q5XJY5|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-MMU-6807878|reactome:R-MMU-6811434 ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 - comment:mint - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:9DuViv4OSAkhnWe4lDxw1efwckE10090 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rigid:pcq3Wn4P2KikEN82q2Tth7RhG20 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3TDX8 uniprotkb:Q83A33 intact:EBI-7928047|uniprotkb:Q6VXY4|uniprotkb:Q8BTI5|uniprotkb:Q3U012|uniprotkb:Q8BJV8|intact:UNK-5537179|uniprotkb:Q3TJH3|uniprotkb:Q6VXY5|uniprotkb:E9Q129|uniprotkb:Q8R3H8|uniprotkb:Q99LY4|uniprotkb:Q99P29|ensembl:ENSMUSP00000126119 intact:EBI-21286457|ensemblbacteria:AAO91562 psi-mi:nb5r4_mouse(display_long)|uniprotkb:Cyb5r4(gene name)|psi-mi:Cyb5r4(display_short)|uniprotkb:Ncb5or(gene name synonym)|uniprotkb:Flavohemoprotein b5/b5R(gene name synonym)|uniprotkb:cb5/cb5R(gene name synonym)|uniprotkb:N-terminal cytochrome b5 and cytochrome b5 oxidoreductase domain-containing protein(gene name synonym) psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288132|imex:IM-26899-195 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077157.2|refseq:XP_006511262.1|ensembl:ENSMUSG00000032872(gene)|ensembl:ENSMUST00000168529(transcript)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0004128"("cytochrome-b5 reductase activity, acting on NAD(P)H")|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006739"(NADP metabolic process)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016653"("oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor")|go:"GO:0020037"(heme binding)|interpro:IPR001199(Cytochrome b5)|go:"GO:0030073"(insulin secretion)|go:"GO:0042168"(heme metabolic process)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0046677"(response to antibiotic)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001834("NADH:cytochrome b5 reductase (CBR)")|interpro:IPR007052(CS domain)|interpro:IPR008333(Oxidoreductase FAD-binding region)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR017927|interpro:IPR017938|interpro:IPR018506|interpro:IPR036400|interpro:IPR037908|interpro:IPR039261|mint:Q3TDX8|reactome:R-MMU-1237044|go:"GO:0046872"(metal ion binding)|go:"GO:0048468"(cell development)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0072593"(reactive oxygen species metabolic process) ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 - comment:mint|function:"NADH-cytochrome b5 reductase involved in endolasmic reticulum stress response pathway. Plays a critical role in protecting pancreatic beta-cells against oxidant stress, possibly by protecting the cell from excess buildup of reactive oxygen species (ROS)" - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:j19wK584v3ZVxPwALGRiJ1DnnvU10090 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rigid:PL1bI6LzqCvh5OSzuvp/nA5qm70 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A11 uniprotkb:Q9WTX5 intact:EBI-21286600|ensemblbacteria:AAO91591 intact:EBI-1202363|uniprotkb:Q8C5H6|ensembl:ENSMUSP00000038744|ensembl:ENSMUSP00000104700 psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name) psi-mi:skp1_mouse(display_long)|uniprotkb:Skp1(gene name)|psi-mi:Skp1(display_short)|uniprotkb:Skp1a(gene name synonym)|uniprotkb:S-phase kinase-associated protein 1A(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:p19A(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288363|imex:IM-26899-731 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91591(transcript)|ensemblbacteria:CBUA0014(gene)|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047|mint:Q83A11 refseq:NP_035673.3|refseq:XP_006532849.1|go:"GO:0019904"(protein domain specific binding)|ensembl:ENSMUSG00000036309(gene)|ensembl:ENSMUST00000037324(transcript)|ensembl:ENSMUST00000109072(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:Q9WTX5|reactome:R-MMU-1169091|reactome:R-MMU-1170546|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2565942|reactome:R-MMU-2871837|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5676590|reactome:R-MMU-5684264|reactome:R-MMU-68949|reactome:R-MMU-69231|reactome:R-MMU-8854050|reactome:R-MMU-8939902|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-917937|reactome:R-MMU-9708530|reactome:R-MMU-983168|dip:DIP-38596N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377 rogid:qGk720KMKAbBPguy2tmUOZsLxRQ10090 rigid:kByXQOMRvc7UEWAkTP8ftAiT7z4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A33 uniprotkb:Q9CWJ3 intact:EBI-21286457|ensemblbacteria:AAO91562 intact:EBI-21288162|ensembl:ENSMUSP00000028552|uniprotkb:Q3U7P7|uniprotkb:Q8C7R6 psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:ktbl1_mouse(display_long)|uniprotkb:Katnbl1(gene name)|psi-mi:Katnbl1(display_short)|uniprotkb:Katanin p80 subunit B-like 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288178|imex:IM-26899-813 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 ensembl:ENSMUSG00000027132(gene)|ensembl:ENSMUST00000028552(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008017"(microtubule binding)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR028021|interpro:IPR042404|mint:Q9CWJ3|refseq:NP_077216.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rogid:perK+7NQmja3GdDbI07S0yg9LBs10090 rigid:M7PbjXNRCUkzSrlEFSgM+v9JPxU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A11 uniprotkb:D3Z3N4 intact:EBI-21286600|ensemblbacteria:AAO91591 intact:EBI-11517461|ensembl:ENSMUSP00000020263 psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name) psi-mi:d3z3n4_mouse(display_long)|uniprotkb:Hnrnph3(gene name)|psi-mi:Hnrnph3(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288351|imex:IM-26899-827 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91591(transcript)|ensemblbacteria:CBUA0014(gene)|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047|mint:Q83A11 refseq:NP_001073293.1|refseq:XP_006513900.1|refseq:XP_006513901.1|ensembl:ENSMUSG00000020069(gene)|ensembl:ENSMUST00000020263(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:0005634"(nucleus)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034969|interpro:IPR034970|interpro:IPR035979|mint:D3Z3N4 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377 rogid:Te+IJ76PZRXSgcY4YRpeaCE/Sjo10090 rigid:d7g4XU4xcLmXtqL7tf1A5ZDpVV4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A11 uniprotkb:Q64516 intact:EBI-21286600|ensemblbacteria:AAO91591 intact:EBI-2934776|ensembl:ENSMUSP00000109611|uniprotkb:B1ASZ1|uniprotkb:Q8C2M1|uniprotkb:Q8C8X0 psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name) psi-mi:glpk_mouse(display_long)|uniprotkb:Gk(gene name)|psi-mi:Gk(display_short)|uniprotkb:Gyk(gene name synonym)|uniprotkb:"ATP:glycerol 3-phosphotransferase"(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288345|imex:IM-26899-537 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91591(transcript)|ensemblbacteria:CBUA0014(gene)|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047|mint:Q83A11 ensembl:ENSMUSG00000025059(gene)|ensembl:ENSMUST00000113978(transcript)|go:"GO:0004370"(glycerol kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006071"(glycerol metabolic process)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0016310"(phosphorylation)|go:"GO:0016773"(phosphotransferase activity, alcohol group as acceptor)|go:"GO:0019217"(regulation of fatty acid metabolic process)|refseq:NP_001281069.1|go:"GO:0019563"(glycerol catabolic process)|go:"GO:0042393"(histone binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0045471"(response to ethanol)|go:"GO:0046167"(glycerol-3-phosphate biosynthetic process)|interpro:IPR000577(Carbohydrate kinase, FGGY)|interpro:IPR005999(Glycerol kinase)|interpro:IPR018483|interpro:IPR018484|interpro:IPR018485|interpro:IPR042018|interpro:IPR043129|mint:Q64516|reactome:R-MMU-75109|refseq:NP_032220.1|refseq:NP_997609.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377 rogid:bHC+PxAdZoLK5OePnd3jbHDzF1c10090 rigid:PtEeqNrUrTraIzEesCvzHOLP7Cc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BVW0 uniprotkb:Q83A11 intact:EBI-8320824|uniprotkb:Q8BH03|intact:MINT-4095605 intact:EBI-21286600|ensemblbacteria:AAO91591 psi-mi:ganc_mouse(display_long)|uniprotkb:Ganc(gene name)|psi-mi:Ganc(display_short) psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288339|imex:IM-26899-729 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR030458|interpro:IPR025887|interpro:IPR017853(Glycoside hydrolase, catalytic core)|refseq:NP_766260.2|interpro:IPR011013(Glycoside hydrolase-type carbohydrate-binding)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|mint:Q8BVW0|interpro:IPR000322(Glycoside hydrolase, family 31)|go:"GO:0004553"(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:"GO:0004558"(alpha-1,4-glucosidase activity)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006491"(N-glycan processing)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0032450"(maltose alpha-glucosidase activity)|go:"GO:0090599"(alpha-glucosidase activity) ensemblbacteria:AAO91591(transcript)|ensemblbacteria:CBUA0014(gene)|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047|mint:Q83A11 - comment:mint|function:Has alpha-glucosidase activity - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JF6lunjNfLWysg0EgSDCKDGOBWs10090 rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377 rigid:mOtPNYqceURZzIrsE/5zBvYrvuo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A11 uniprotkb:P28658 intact:EBI-21286600|ensemblbacteria:AAO91591 intact:EBI-4284019|uniprotkb:Q543S3|uniprotkb:Q99LP5|uniprotkb:Q9D1I1|ensembl:ENSMUSP00000132450 psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name) psi-mi:atx10_mouse(display_long)|uniprotkb:Atxn10(gene name)|psi-mi:Atxn10(display_short)|uniprotkb:Sca10(gene name synonym)|uniprotkb:Brain protein E46(gene name synonym)|uniprotkb:Spinocerebellar ataxia type 10 protein homolog(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288333|imex:IM-26899-535 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91591(transcript)|ensemblbacteria:CBUA0014(gene)|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047|mint:Q83A11 refseq:NP_058539.2|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060271"(cilium assembly)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019156|mint:P28658|go:"GO:0042802"(identical protein binding)|ensembl:ENSMUSG00000016541(gene)|ensembl:ENSMUST00000163242(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development) - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377 rogid:cxYVinpnTlmg90CtHSELPioHT6s10090 rigid:W7Ol55FyY+KMZaFkA4h6doHJr78 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23949 uniprotkb:Q83A33 intact:EBI-8392537|intact:MINT-4137984|uniprotkb:B9EIF6|uniprotkb:Q3TCE3|uniprotkb:Q3TU59|ensembl:ENSMUSP00000050820 intact:EBI-21286457|ensemblbacteria:AAO91562 psi-mi:tisd_mouse(display_long)|uniprotkb:Zfp36l2(gene name)|psi-mi:Zfp36l2(display_short)|uniprotkb:Tis11d(gene name synonym)|uniprotkb:Butyrate response factor 2(gene name synonym)|uniprotkb:TPA-induced sequence 11d(gene name synonym)|uniprotkb:Zinc finger protein 36, C3H1 type-like 2(gene name synonym) psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288327|imex:IM-26899-93 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001806.1|ensembl:ENSMUSG00000045817(gene)|ensembl:ENSMUST00000060366(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0009611"(response to wounding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901991"(negative regulation of mitotic cell cycle phase transition)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR007635(Tis11B like protein, N-terminal)|interpro:IPR036855|mint:P23949 ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 - function:"Probable regulatory protein involved in regulating the response to growth factors. RNA-binding protein that binds to 5'UUAUUUAUUU-3' core sequence. Binds to the class II AU-rich element (ARE) in the 3'-UTR of target mRNAs and promotes their deadenylation and degradation"|comment:mint - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:iPHaXGG46do54N3HBj7ZIqbmCes10090 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rigid:H7Y3gvmOROPkKkXLcGmFaBW5F8I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A33 uniprotkb:Q9ERF3 intact:EBI-21286457|ensemblbacteria:AAO91562 intact:EBI-6094557|uniprotkb:Q3U562|uniprotkb:Q9CZP1|ensembl:ENSMUSP00000056359|ensembl:ENSMUSP00000113560 psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:wdr61_mouse(display_long)|uniprotkb:Wdr61(gene name)|psi-mi:Wdr61(display_short)|uniprotkb:Meiotic recombination REC14 protein homolog(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288321|imex:IM-26899-727 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 refseq:NP_001020546.1|refseq:NP_075680.1|ensembl:ENSMUSG00000061559(gene)|ensembl:ENSMUST00000051822(transcript)|ensembl:ENSMUST00000121204(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0055087"(Ski complex)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9ERF3|reactome:R-MMU-112382|reactome:R-MMU-429958|reactome:R-MMU-674695|reactome:R-MMU-75955|reactome:R-MMU-8866654 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rogid:r5TxJiuiFNk5dUDuhzCqFfFXX/M10090 rigid:8tBQmZLwF7YeNmpgP9UnFt10bZ4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BY87 uniprotkb:Q83A33 intact:EBI-8420047|intact:MINT-4110662|uniprotkb:Q80V06|uniprotkb:Q8BUW4|uniprotkb:Q91X25|uniprotkb:Q6KAR9|uniprotkb:Q8BI16|uniprotkb:Q32NY0|uniprotkb:Q5EBP2|uniprotkb:Q8BI15|uniprotkb:Q8BHU1|ensembl:ENSMUSP00000147619 intact:EBI-21286457|ensemblbacteria:AAO91562 psi-mi:ubp47_mouse(display_long)|uniprotkb:Usp47(gene name)|psi-mi:Usp47(display_short)|uniprotkb:Ubiquitin thioesterase 47(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 47(gene name synonym)|uniprotkb:Deubiquitinating enzyme 47(gene name synonym) psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288315|imex:IM-26899-433 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_598519.2|refseq:NP_796223.2|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR029071|interpro:IPR038765|mint:Q8BY87|reactome:R-MMU-5689880|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|ensembl:ENSMUSG00000059263(gene)|ensembl:ENSMUST00000210309(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006284"(base-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034644"(cellular response to UV) ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 - comment:mint - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:+7NgU4JY6ZGpOCRW+1vJE0sS6os10090 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rigid:HbfdVGYHOuDgkHhCTVSs44kIbMM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JKB1 uniprotkb:Q83A33 intact:EBI-8312797|ensembl:ENSMUSP00000002289|intact:MINT-1856010|uniprotkb:Q9EQX7 intact:EBI-21286457|ensemblbacteria:AAO91562 psi-mi:uchl3_mouse(display_long)|uniprotkb:Uchl3(gene name)|psi-mi:Uchl3(display_short)|uniprotkb:Ubiquitin thioesterase L3(gene name synonym) psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288309|imex:IM-26899-825 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022111(gene)|ensembl:ENSMUST00000002289(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008233"(peptidase activity)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030163"(protein catabolic process)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR036959|interpro:IPR038765|mint:Q9JKB1|reactome:R-MMU-5689603|reactome:R-MMU-8866652|reactome:R-MMU-8951664|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042755"(eating behavior)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0101005"(deubiquitinase activity)|refseq:NP_057932.2 ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 - comment:mint|function:Ubiquitin-protein hydrolase is involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of either ubiquitin or NEDD8. May be involved in working memory - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:KYxmQ3PpzIYoABeLUbKtHv8IfiA10090 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rigid:WwuY+5pPSflH6VcCySTXcYaKhLw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A33 uniprotkb:Q8CGF5 intact:EBI-21286457|ensemblbacteria:AAO91562 intact:EBI-21288280|ensembl:ENSMUSP00000029777|ensembl:ENSMUSP00000119468|ensembl:ENSMUSP00000120821|uniprotkb:Q9D4Q8 psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:tlcd4_mouse(display_long)|uniprotkb:Tlcd4(gene name)|psi-mi:Tlcd4(display_short)|uniprotkb:Tmem56(gene name synonym)|uniprotkb:Transmembrane protein 56(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288303|imex:IM-26899-823 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|mint:Q8CGF5|go:"GO:0055088"(lipid homeostasis)|ensembl:ENSMUSG00000028132(gene)|ensembl:ENSMUST00000029777(transcript)|ensembl:ENSMUST00000128909(transcript)|ensembl:ENSMUST00000155309(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|refseq:NP_849267.1|refseq:XP_006502540.1|refseq:XP_006502541.1|refseq:XP_006502543.1|refseq:XP_011238639.1|refseq:XP_011238641.1|refseq:XP_011238642.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rogid:d6hk0/GTxU4Id/Q4xw2jHE2Acx810090 rigid:1h9kBjQas+bD4PMT4f4cYeSxh1k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A33 uniprotkb:P10711 intact:EBI-21286457|ensemblbacteria:AAO91562 intact:EBI-9988575|uniprotkb:P10712|uniprotkb:P23713|ensembl:ENSMUSP00000080266 psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:tcea1_mouse(display_long)|uniprotkb:Tcea1(gene name)|psi-mi:Tcea1(display_short)|uniprotkb:Tceat(gene name synonym)|uniprotkb:Transcription elongation factor S-II protein 1(gene name synonym)|uniprotkb:Transcription elongation factor TFIIS.o(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288274|imex:IM-26899-199 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 refseq:NP_001153222.1|refseq:NP_001153223.1|refseq:NP_035671.1|ensembl:ENSMUSG00000033813(gene)|ensembl:ENSMUST00000081551(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|go:"GO:0030218"(erythrocyte differentiation)|interpro:IPR003618(Transcription elongation factor S-II, central region)|interpro:IPR006289(Transcription elongation factor, TFIIS)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR017923|interpro:IPR035100|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR035441|interpro:IPR036575|mint:P10711|reactome:R-MMU-112382|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-75955 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rogid:8EelzoMlCCdII18TQKPxJQOwZh010090 rigid:eZ7ZsjdsG/w5xrFA0NorzQD/to4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P97868 uniprotkb:Q83A33 intact:EBI-8329311|uniprotkb:P70287|uniprotkb:Q8R399|uniprotkb:Q3TTR9|uniprotkb:Q4U217|uniprotkb:Q3UMP7|intact:MINT-4106375|uniprotkb:Q3TUM7|uniprotkb:Q7TT06|uniprotkb:Q8BNY8|ensembl:ENSMUSP00000049528 intact:EBI-21286457|ensemblbacteria:AAO91562 psi-mi:rbbp6_mouse(display_long)|uniprotkb:Rbbp6(gene name)|psi-mi:Rbbp6(display_short)|uniprotkb:P2pr(gene name synonym)|uniprotkb:Pact(gene name synonym)|uniprotkb:p53-associated cellular protein of testis(gene name synonym)|uniprotkb:Proliferation potential-related protein(gene name synonym)|uniprotkb:Protein P2P-R(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 6(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RBBP6(gene name synonym) psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288268|imex:IM-26899-91 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035377.2|refseq:NP_778188.1|refseq:XP_006507533.1|ensembl:ENSMUSG00000030779(gene)|ensembl:ENSMUST00000052135(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006260"(DNA replication)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006397"(mRNA processing)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061053"(somite development)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR003613(U box)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014891(DWNN domain)|interpro:IPR025829|interpro:IPR033489|interpro:IPR036875|mint:P97868|reactome:R-MMU-9013422|reactome:R-MMU-983168 ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 - comment:mint - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:mpPVAoOa4h9lRTIZhKfpI5Po5cg10090 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rigid:F6BN/LvEdPkVkFZaR70fbDqQzbE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A33 uniprotkb:Q9R1P0 intact:EBI-21286457|ensemblbacteria:AAO91562 intact:EBI-772804|uniprotkb:Q3THT1|ensembl:ENSMUSP00000034848 psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:psa4_mouse(display_long)|uniprotkb:Proteasome component C9(gene name synonym)|uniprotkb:Macropain subunit C9(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C9(gene name synonym)|uniprotkb:Proteasome subunit L(gene name synonym)|uniprotkb:Psma4(gene name)|psi-mi:Psma4(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288262|imex:IM-26899-821 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 refseq:NP_036096.1|refseq:XP_006511261.1|ensembl:ENSMUSG00000032301(gene)|ensembl:ENSMUST00000034848(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034647|mint:Q9R1P0|rcsb pdb:3UNB|rcsb pdb:3UNE|rcsb pdb:3UNF|rcsb pdb:3UNH|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rogid:6Dp8VODK8RbwARcOjjpMbvCN1pU10090 rigid:wx7CdVoio7aBVRNtQ/B2vuRN0jY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A33 uniprotkb:B9EJ80 intact:EBI-21286457|ensemblbacteria:AAO91562 intact:EBI-21288229|ensembl:ENSMUSP00000096880|uniprotkb:Q3UMB1 psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:pdzd8_mouse(display_long)|uniprotkb:Pdzd8(gene name)|psi-mi:Pdzd8(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288256|imex:IM-26899-819 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 go:"GO:0006869"(lipid transport)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR031468|interpro:IPR036034|interpro:IPR039275|interpro:IPR041489|mint:B9EJ80|ensembl:ENSMUSG00000074746(gene)|ensembl:ENSMUST00000099274(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|refseq:NP_001028394.2 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rogid:A2ygDLI/FS0k0QYKf8IaFlIm+jA10090 rigid:mzicxuUjYKAmmKa5Xl4qxwLGlNU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A33 uniprotkb:Q9JJN4 intact:EBI-21286457|ensemblbacteria:AAO91562 intact:EBI-21287815|ensembl:ENSMUSP00000099700|uniprotkb:B9EHG5 psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:sco2a_mouse(display_long)|uniprotkb:Oxct2a(gene name)|psi-mi:Oxct2a(display_short)|uniprotkb:3-oxoacid CoA-transferase 2A(gene name synonym)|uniprotkb:"Testis-specific succinyl-CoA:3-oxoacid CoA-transferase 1"(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288223|imex:IM-26899-725 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0008260"(3-oxoacid CoA-transferase activity)|go:"GO:0008410"(CoA-transferase activity)|go:"GO:0046950"(cellular ketone body metabolic process)|go:"GO:0046952"(ketone body catabolic process)|interpro:IPR004163(Coenzyme A transferase binding site)|interpro:IPR004164(Coenzyme A transferase active site)|interpro:IPR004165(Coenzyme A transferase)|interpro:IPR012791(3-oxoacid CoA-transferase, subunit B)|interpro:IPR012792(3-oxoacid CoA-transferase, subunit A)|interpro:IPR014388(3-oxoacid CoA-transferase)|interpro:IPR037171|mint:Q9JJN4|ensembl:ENSMUSG00000076436(gene)|ensembl:ENSMUST00000102640(transcript)|go:"GO:0005739"(mitochondrion)|refseq:NP_071316.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rogid:MYuL2D1hHi3ql+ccOwNxex3OG9Y10090 rigid:/mBGn3Baw83O5FK6Vy1d6eHCL9c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z0J0 uniprotkb:Q83A33 intact:EBI-8408018|intact:MINT-4104065|uniprotkb:Q3UB23|ensembl:ENSMUSP00000021668 intact:EBI-21286457|ensemblbacteria:AAO91562 psi-mi:npc2_mouse(display_long)|uniprotkb:Npc2(gene name)|psi-mi:Npc2(display_short)|uniprotkb:Niemann Pick type C2 protein homolog(gene name synonym)|uniprotkb:Epididymal secretory protein E1(gene name synonym) psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288217|imex:IM-26899-817 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_075898.1|ensembl:ENSMUSG00000021242(gene)|ensembl:ENSMUST00000021668(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015918"(sterol transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0030301"(cholesterol transport)|go:"GO:0032366"(intracellular sterol transport)|go:"GO:0032367"(intracellular cholesterol transport)|go:"GO:0032934"(sterol binding)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR003172(MD-2-related lipid-recognition)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR033916|interpro:IPR039670|mint:Q9Z0J0|reactome:R-MMU-6798695|reactome:R-MMU-8964038 ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 - comment:mint|function:May be involved in the regulation of the lipid composition of sperm membranes during the maturation in the epididymis - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:eDUNxC5PVN2I/spwfEGtuIV7dOI10090 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rigid:Are5FaFIUKrLg7rGA3cAJ7KVOmY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A33 uniprotkb:Q6B966 intact:EBI-21286457|ensemblbacteria:AAO91562 intact:EBI-21288190|ensembl:ENSMUSP00000081819|uniprotkb:B2RUL1|uniprotkb:Q66X14 psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:nal14_mouse(display_long)|uniprotkb:Nlrp14(gene name)|psi-mi:Nlrp14(display_short)|uniprotkb:Nalp14(gene name synonym)|uniprotkb:Germ cell specific leucine-rich repeat NTPase(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288211|imex:IM-26899-631 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 ensembl:ENSMUSG00000016626(gene)|ensembl:ENSMUST00000084763(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041075|interpro:IPR041267|mint:Q6B966|refseq:NP_001002894.2|refseq:XP_011240240.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rogid:d7H+cuFxcXpdJYXxs4XutRLZTrU10090 rigid:vQjwgPdV1NRgtTFadCbktZ23cnI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A33 uniprotkb:O08601 intact:EBI-21286457|ensemblbacteria:AAO91562 intact:EBI-1183611|uniprotkb:B2CXA7|uniprotkb:Q3UJA0|uniprotkb:Q91X33|ensembl:ENSMUSP00000029805 psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:mtp_mouse(display_long)|uniprotkb:Mttp(gene name)|psi-mi:Mttp(display_short)|uniprotkb:Mtp(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288184|imex:IM-26899-815 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 refseq:NP_001156929.1|refseq:NP_032668.2|ensembl:ENSMUSG00000028158(gene)|ensembl:ENSMUST00000029805(transcript)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006497"(protein lipidation)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006869"(lipid transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0009306"(protein secretion)|go:"GO:0015914"(phospholipid transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031982"(vesicle)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034197"(triglyceride transport)|go:"GO:0034374"(low-density lipoprotein particle remodeling)|go:"GO:0034377"(plasma lipoprotein particle assembly)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0006629"(lipid metabolic process)|refseq:XP_006501165.1|refseq:XP_006501166.1|go:"GO:0043235"(receptor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051592"(response to calcium ion)|go:"GO:0120014"(phospholipid transfer activity)|go:"GO:0120019"(phosphatidylcholine transfer activity)|go:"GO:0120020"(cholesterol transfer activity)|go:"GO:0140344"(triglyceride transfer activity)|go:"GO:1902388"(ceramide 1-phosphate transfer activity)|go:"GO:1904121"(phosphatidylethanolamine transfer activity)|interpro:IPR001747(Lipid transport protein, N-terminal)|interpro:IPR011030(Vitellinogen, superhelical)|interpro:IPR015816(Vitellinogen, beta-sheet N-terminal)|interpro:IPR015819(Lipid transport protein, beta-sheet shell)|interpro:IPR039988|mint:O08601|go:"GO:0042953"(lipoprotein transport)|reactome:R-MMU-8963888|reactome:R-MMU-8866423|refseq:XP_017174963.1|refseq:XP_017174964.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rogid:7VKaqT/iEzsvkw6SA1aX3ef2sgA10090 rigid:SHqYw8aofWvMcNgym/6EHFEbLbQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q61937 uniprotkb:Q83A11 intact:EBI-626362|ensembl:ENSMUSP00000075067 intact:EBI-21286600|ensemblbacteria:AAO91591 psi-mi:npm_mouse(display_long)|uniprotkb:Nucleolar phosphoprotein B23(gene name synonym)|uniprotkb:Numatrin(gene name synonym)|uniprotkb:Nucleolar protein NO38(gene name synonym)|uniprotkb:Npm1(gene name)|psi-mi:Npm1(display_short) psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name) psi-mi:"MI:0398"(two hybrid pooling approach) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288357|imex:IM-26899-311 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032071"(regulation of endodeoxyribonuclease activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0031328"(positive regulation of cellular biosynthetic process)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051054"(positive regulation of DNA metabolic process)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060699"(regulation of endoribonuclease activity)|go:"GO:0060735"(regulation of eIF2 alpha phosphorylation by dsRNA)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097421"(liver regeneration)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902629"(regulation of mRNA stability involved in cellular response to UV)|go:"GO:1902751"(positive regulation of cell cycle G2/M phase transition)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR032569|interpro:IPR036824|mint:Q61937|rcsb pdb:4N8M|reactome:R-MMU-3899300|reactome:R-MMU-606279|reactome:R-MMU-6804115|reactome:R-MMU-8869496|ensembl:ENSMUSG00000057113(gene)|ensembl:ENSMUST00000075641(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0000448"("cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001652"(granular component)|go:"GO:0002039"(p53 binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006407"(rRNA export from nucleus)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009303"(rRNA transcription)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0010825"(positive regulation of centrosome duplication)|go:"GO:0010826"(negative regulation of centrosome duplication)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0019843"(rRNA binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030957"(Tat protein binding)|refseq:NP_032748.1 ensemblbacteria:AAO91591(transcript)|ensemblbacteria:CBUA0014(gene)|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047|mint:Q83A11 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:i/cYJMIvj0nTZoQNh4thiojopbA10090 rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377 rigid:FS3wXr77leojyDmKtcR5nBGDZNI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q68CP9 uniprotkb:Q83D60 intact:EBI-637818|uniprotkb:Q15KG9|uniprotkb:Q5EB51|uniprotkb:Q645I3|uniprotkb:Q6ZRY5|uniprotkb:Q7Z3I5|uniprotkb:Q86T28|uniprotkb:Q96SJ6|uniprotkb:Q9HCL5|ensembl:ENSP00000335044 intact:EBI-21285556|ensemblbacteria:AAO90413 psi-mi:arid2_human(display_long)|uniprotkb:BRG1-associated factor 200(gene name synonym)|uniprotkb:Zinc finger protein with activation potential(gene name synonym)|uniprotkb:Zipzap/p200(gene name synonym)|uniprotkb:ARID2(gene name)|psi-mi:ARID2(display_short)|uniprotkb:KIAA1557(gene name synonym)|uniprotkb:BAF200(gene name synonym) psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288381|imex:IM-26899-829 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_689854.2|ensembl:ENSG00000189079(gene)|ensembl:ENST00000334344(transcript)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042592"(homeostatic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048568"(embryonic organ development)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR036388|interpro:IPR036390|interpro:IPR036431|mint:Q68CP9|reactome:R-HSA-3214858|reactome:R-HSA-8939243|dip:DIP-33391N|refseq:NP_001334768.1|ensembl:ENSP00000335044 ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:7AJ6PqICERVZS+s3sZBIBODzs/I9606 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rigid:+TsiYi8O1ve39fliPp/FgOP8wPs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DE4 uniprotkb:Q96ND8 intact:EBI-21285423|ensemblbacteria:AAO90328 intact:EBI-21285519|ensembl:ENSP00000291598|ensembl:ENSP00000388502|uniprotkb:O14850|uniprotkb:Q2NKK3 psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name) psi-mi:zn583_human(display_long)|uniprotkb:ZNF583(gene name)|psi-mi:ZNF583(display_short)|uniprotkb:Zinc finger protein L3-5(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288375|imex:IM-26899-733 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90328(transcript)|ensemblbacteria:CBU_0794(gene)|refseq:NP_819814.1|refseq:WP_010957806.1|mint:Q83DE4 ensembl:ENSG00000198440(gene)|ensembl:ENST00000291598(transcript)|ensembl:ENST00000333201(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|mint:Q96ND8|reactome:R-HSA-212436|refseq:NP_001153332.1|refseq:NP_001153333.1|refseq:NP_689691.2|refseq:XP_011524819.1|refseq:XP_016881839.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:XVA7R483yYdpYkhCnAqOzU8u000227377 rogid:K5sTOQhO2w/s5N/S+t9aFNGP/Ns9606 rigid:+yL4MNs50rgEnydBlD4VfoBYthw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q9UBW7 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-2797576|uniprotkb:Q5W0T3|uniprotkb:O43434|uniprotkb:O43212|uniprotkb:Q5W0Q4|uniprotkb:Q9UEU2|uniprotkb:Q9H538|uniprotkb:Q9H0V5|uniprotkb:Q8NE39|uniprotkb:Q63HP0|uniprotkb:A6NI02|uniprotkb:A6NDG0|uniprotkb:O60898|ensembl:ENSP00000372324|ensembl:ENSP00000372327|ensembl:ENSP00000479904 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:zmym2_human(display_long)|uniprotkb:FIM(gene name synonym)|uniprotkb:RAMP(gene name synonym)|uniprotkb:ZNF198(gene name synonym)|uniprotkb:Fused in myeloproliferative disorders protein(gene name synonym)|uniprotkb:Rearranged in atypical myeloproliferative disorder protein(gene name synonym)|uniprotkb:Zinc finger protein 198(gene name synonym)|uniprotkb:ZMYM2(gene name)|psi-mi:ZMYM2(display_short) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288447|imex:IM-26899-835 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_001177893.1|refseq:NP_001177894.1|refseq:NP_003444.1|refseq:NP_932072.1|ensembl:ENSP00000372324|ensembl:ENSP00000372327|ensembl:ENSP00000479904|refseq:XP_005266577.1|ensembl:ENSG00000121741(gene)|ensembl:ENST00000382871(transcript)|ensembl:ENST00000382874(transcript)|ensembl:ENST00000610343(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR021893|mint:Q9UBW7|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-9703465|refseq:XP_016876218.1|refseq:XP_011533526.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:rsxYDcDeR5x2Lt3phHNYpCjf9KA9606 rigid:V1C2fEBWAyD9nhn6UKIoHHd5YVU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:P49802 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-1754797|uniprotkb:Q8TD66|uniprotkb:Q8TD67|uniprotkb:Q9UNU7|uniprotkb:Q9Y6B9|uniprotkb:Q5T3H4|uniprotkb:Q8WW09|ensembl:ENSP00000404399 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:rgs7_human(display_long)|uniprotkb:RGS7(gene name)|psi-mi:RGS7(display_short) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288441|imex:IM-26899-205 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_001269702.1|refseq:NP_001269704.1|refseq:NP_001269707.1|refseq:NP_002915.3|refseq:XP_005273275.1|dip:DIP-40869N|interpro:IPR036390|interpro:IPR040759|mint:P49802|rcsb pdb:2A72|rcsb pdb:2D9J|reactome:R-HSA-418594|reactome:R-HSA-6814122|interpro:IPR036388|go:"GO:0043547"(positive regulation of GTPase activity)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR015898(G-protein, gamma-like subunit)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR036284|ensembl:ENSG00000182901(gene)|ensembl:ENST00000440928(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR036305 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:epeNPVu00d27S9hlaKto1/bKwhI9606 rigid:HBFX7OQnp4clvuCTuIcXYrvP/tA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q9UNP9 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-591818|uniprotkb:Q3S611|uniprotkb:Q5TGA3|uniprotkb:O43634|uniprotkb:O43635|uniprotkb:Q32Q72|uniprotkb:Q5TGA0|uniprotkb:Q5TGA2|uniprotkb:Q9UIZ5|uniprotkb:B2R971|ensembl:ENSP00000312769 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:ppie_human(display_long)|uniprotkb:Cyclophilin E(gene name synonym)|uniprotkb:Cyclophilin-33(gene name synonym)|uniprotkb:PPIE(gene name)|psi-mi:PPIE(display_short)|uniprotkb:CYP33(gene name synonym)|uniprotkb:Rotamase E(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288435|imex:IM-26899-557 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_006103.1|refseq:NP_982281.1|refseq:NP_001181936.1|refseq:XP_016855540.1|dip:DIP-34757N|ensembl:ENSG00000084072(gene)|ensembl:ENST00000324379(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR016304(Peptidyl-prolyl cis-trans isomerase E)|interpro:IPR020892|interpro:IPR029000|interpro:IPR034168|interpro:IPR035979|mint:Q9UNP9|rcsb pdb:1ZMF|rcsb pdb:2CQB|rcsb pdb:2KU7|rcsb pdb:2KYX|rcsb pdb:2R99|rcsb pdb:3LPY|rcsb pdb:3MDF|rcsb pdb:3UCH|rcsb pdb:5MQF|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6798695|reactome:R-HSA-72163 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:zMkadgyIl5RwvoD3h3vetTqLjg49606 rigid:Ys7GfTvJwmBH8iSN/2XhiHKXDjk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q5JRX3 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-2432778|uniprotkb:B4E0J8|uniprotkb:E7ES23|uniprotkb:B3KMJ6|uniprotkb:O95204|uniprotkb:Q2M2G6|uniprotkb:Q4VBR1|uniprotkb:Q5JRW7|uniprotkb:Q7L5Z7|uniprotkb:Q9BSI6|uniprotkb:Q9BVJ5|uniprotkb:Q9UPP8|uniprotkb:C9JSL2|ensembl:ENSP00000224949 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:prep_human(display_long)|uniprotkb:PITRM1(gene name)|psi-mi:PITRM1(display_short)|uniprotkb:KIAA1104(gene name synonym)|uniprotkb:MP1(gene name synonym)|uniprotkb:Pitrilysin metalloproteinase 1(gene name synonym)|uniprotkb:PREP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288429|imex:IM-26899-99 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_001229236.1|refseq:NP_001229238.1|refseq:NP_055704.2|dip:DIP-52900N|ensembl:ENSG00000107959(gene)|ensembl:ENST00000224949(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006508"(proteolysis)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016485"(protein processing)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|interpro:IPR013578(Peptidase M16C associated)|mint:Q5JRX3|rcsb pdb:4L3T|rcsb pdb:4NGE|rcsb pdb:4RPU|reactome:R-HSA-1268020 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:1kEY/XJB5fwgNRoM9u9ZGT+VrS09606 rigid:DFGF+X6QcG/CnhozoDIq70n0zhE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:P51955 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-633182|uniprotkb:Q53FD6|uniprotkb:Q5VXZ1|intact:EBI-4311380|uniprotkb:Q5I1Z9|uniprotkb:Q6NZX8|uniprotkb:Q7Z634|uniprotkb:Q86XH2|uniprotkb:Q96QN9|ensembl:ENSP00000355966 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:nek2_human(display_long)|uniprotkb:NEK2A(gene name synonym)|uniprotkb:NimA-like protein kinase 1(gene name synonym)|uniprotkb:HSPK 21(gene name synonym)|uniprotkb:NEK2(gene name)|psi-mi:NEK2(display_short)|uniprotkb:NLK1(gene name synonym)|uniprotkb:Never in mitosis A-related kinase 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288423|imex:IM-26899-833 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_001191111.1|refseq:NP_001191112.1|refseq:NP_002488.1|ensembl:ENSG00000117650(gene)|ensembl:ENST00000366999(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0001824"(blastocyst development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030496"(midbody)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0046602"(regulation of mitotic centrosome separation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051299"(centrosome separation)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903126"(negative regulation of centriole-centriole cohesion)|go:"GO:1904355"(positive regulation of telomere capping)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|mint:P51955|rcsb pdb:2JAV|rcsb pdb:2W5A|rcsb pdb:2W5B|rcsb pdb:2W5H|rcsb pdb:2WQO|rcsb pdb:2XK3|rcsb pdb:2XK4|rcsb pdb:2XK6|rcsb pdb:2XK7|rcsb pdb:2XK8|rcsb pdb:2XKC|rcsb pdb:2XKD|rcsb pdb:2XKE|rcsb pdb:2XKF|rcsb pdb:2XNM|rcsb pdb:2XNN|rcsb pdb:2XNO|rcsb pdb:2XNP|rcsb pdb:4A4X|rcsb pdb:4AFE|rcsb pdb:5M51|rcsb pdb:5M53|rcsb pdb:5M55|rcsb pdb:5M57|rcsb pdb:6SGD|rcsb pdb:6SGH|rcsb pdb:6SGI|rcsb pdb:6SGK|rcsb pdb:6SK9|rcsb pdb:6TM5|reactome:R-HSA-179409|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:XP_005273204.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:7iozc82+IF+sGyerzvp571Uc1RM9606 rigid:4Kk5vKrDWEcJ2aNoyeSS8nh5N6s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q9NSE4 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-1054770|uniprotkb:B2RPG8|uniprotkb:Q1M2P9|uniprotkb:Q6PI85|uniprotkb:Q7L439|uniprotkb:Q86WU9|uniprotkb:Q96D91|uniprotkb:Q9H9Q8|uniprotkb:Q9NW42|ensembl:ENSP00000355889 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:syim_human(display_long)|uniprotkb:IARS2(gene name)|psi-mi:IARS2(display_short)|uniprotkb:Isoleucyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288417|imex:IM-26899-555 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_060530.3|ensembl:ENSG00000067704(gene)|ensembl:ENST00000366922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004822"(isoleucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006428"(isoleucyl-tRNA aminoacylation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002301(Isoleucyl-tRNA synthetase, class Ia)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR010663(DNA glycosylase/AP lyase and isoleucyl tRNA synthetase, zinc finger domain)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR023585|interpro:IPR033708|mint:Q9NSE4|reactome:R-HSA-379726 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:+3/hUjD0USVo2/G+Z9aOKpQKwhE9606 rigid:JaivoSuemMz+vo3ANQhZZ/e27nM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q58WW2 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-2559044|ensembl:ENSP00000311949|uniprotkb:Q8TB19|uniprotkb:Q8IXH3|uniprotkb:A2A295|uniprotkb:Q7L8I0|uniprotkb:B4DNB8 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:dcaf6_human(display_long)|uniprotkb:DCAF6(gene name)|psi-mi:DCAF6(display_short)|uniprotkb:IQWD1(gene name synonym)|uniprotkb:Nuclear receptor interaction protein(gene name synonym)|uniprotkb:IQ motif and WD repeat-containing protein 1(gene name synonym)|uniprotkb:Androgen receptor complex-associated protein(gene name synonym)|uniprotkb:MSTP055(orf name) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288387|imex:IM-26899-633 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 ensembl:ENSG00000143164(gene)|ensembl:ENST00000312263(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030374"(nuclear receptor coactivator activity)|refseq:NP_001017977.1|refseq:NP_001185885.1|refseq:NP_001185886.1|refseq:NP_060912.2|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q58WW2|rcsb pdb:3I7O|reactome:R-HSA-8951664|dip:DIP-44678N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:1CtoPWPj6fdryvDlC46pXiUguDc9606 rigid:SL2YGhKlOaBwieGivUD22hIBeA4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:O00399 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-2559415|uniprotkb:B2RAC1|ensembl:ENSP00000221114 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:dctn6_human(display_long)|uniprotkb:DCTN6(gene name)|psi-mi:DCTN6(display_short)|uniprotkb:WS3(gene name synonym)|uniprotkb:Dynactin subunit p27(gene name synonym)|uniprotkb:Protein WS-3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288393|imex:IM-26899-95 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_006562.1|ensembl:ENSG00000104671(gene)|ensembl:ENST00000221114(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0070840"(dynein complex binding)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR027777|mint:O00399|rcsb pdb:3TV0|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:+35O26TEIL5l1I7XrNJcl6BA77c9606 rigid:EfaYGRCh3l3nsqovsatet4tcr0M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q5JVL4 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-743105|ensembl:ENSP00000360107|uniprotkb:Q5XKM4|uniprotkb:Q6E1U7|uniprotkb:Q6E1U8|uniprotkb:Q8WUL2|uniprotkb:Q9NVW6|intact:EBI-11099619|uniprotkb:B4DMU3|uniprotkb:F5GZD8 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:efhc1_human(display_long)|uniprotkb:EFHC1(gene name)|psi-mi:EFHC1(display_short)|uniprotkb:Myoclonin-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288399|imex:IM-26899-97 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 ensembl:ENST00000371068(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000922"(spindle pole)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005813"(centrosome)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0021795"(cerebral cortex cell migration)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051302"(regulation of cell division)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0072686"(mitotic spindle)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006602(Region of unknown function DM10)|interpro:IPR011992(EF-Hand type)|interpro:IPR040193|mint:Q5JVL4|refseq:NP_001165891.1|refseq:NP_060570.2|ensembl:ENSG00000096093(gene) - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:l5I5K4Lgihe08j5BuPBk4uDY+qk9606 rigid:0I1OEHD17+5v0ClLdq5V/RPS5Q4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q9NP50 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-741906|ensembl:ENSP00000337477|ensembl:ENSP00000393279|ensembl:ENSP00000479093|ensembl:ENSP00000488570|uniprotkb:Q9BSZ8|uniprotkb:D3DUV8 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:shcaf_human(display_long)|uniprotkb:SINHCAF(gene name)|psi-mi:SINHCAF(display_short)|uniprotkb:C12orf14(gene name synonym)|uniprotkb:FAM60A(gene name synonym)|uniprotkb:Protein FAM60A(gene name synonym)|uniprotkb:Tera protein homolog(gene name synonym)|uniprotkb:L4(orf name) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288405|imex:IM-26899-539 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 ensembl:ENSG00000139146(gene)|ensembl:ENSG00000276371(gene)|ensembl:ENST00000337682(transcript)|ensembl:ENST00000454658(transcript)|ensembl:ENST00000617411(transcript)|ensembl:ENST00000633702(transcript)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0045596"(negative regulation of cell differentiation)|interpro:IPR026065|mint:Q9NP50|refseq:NP_001129283.1|refseq:NP_001129284.1|refseq:NP_067061.1|refseq:XP_016875247.1|refseq:XP_016875248.1|refseq:XP_016875249.1|refseq:XP_016875250.1|refseq:XP_016875251.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:LVESO8KQhobNYQduBQ/iAmNaNTM9606 rigid:UJqXZov6x8YBXcn0B7qOGuDBNCk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q9NXN4 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-10316460|uniprotkb:Q96DZ0|ensembl:ENSP00000358451 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:gdap2_human(display_long)|uniprotkb:GDAP2(gene name)|psi-mi:GDAP2(display_short) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288411|imex:IM-26899-831 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_001129061.1|refseq:NP_060156.1|ensembl:ENSG00000196505(gene)|ensembl:ENST00000369443(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0032526"(response to retinoic acid)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR002589(Appr-1-p processing)|interpro:IPR035793|interpro:IPR036865|interpro:IPR043472|mint:Q9NXN4|rcsb pdb:4UML - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:2fjIQzKGImu2CwNw2ul5gti/28g9606 rigid:a89t1FSvlGWGh/UMdVF4fI3ASiI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:Q9UIJ7 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-3916527|uniprotkb:Q5VYW6|uniprotkb:Q9NPB4|uniprotkb:Q9H576|uniprotkb:D3DRI1|uniprotkb:Q9HC01|uniprotkb:B4DP58|uniprotkb:E7ET30|ensembl:ENSP00000371230 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:kad3_human(display_long)|uniprotkb:AK3(gene name)|psi-mi:AK3(display_short)|uniprotkb:AK3L1(gene name synonym)|uniprotkb:AK6(gene name synonym)|uniprotkb:AKL3L(gene name synonym)|uniprotkb:Adenylate kinase 3(gene name synonym)|uniprotkb:Adenylate kinase 3 alpha-like 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288453|imex:IM-26899-313 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 refseq:NP_001186781.1|refseq:NP_001186782.1|refseq:NP_001186784.1|refseq:NP_001186785.1|refseq:NP_057366.2|ensembl:ENSG00000147853(gene)|ensembl:ENST00000381809(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006172"(ADP biosynthetic process)|go:"GO:0007596"(blood coagulation)|go:"GO:0009142"(nucleoside triphosphate biosynthetic process)|go:"GO:0046033"(AMP metabolic process)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046041"(ITP metabolic process)|go:"GO:0046051"(UTP metabolic process)|go:"GO:0046899"(nucleoside triphosphate adenylate kinase activity)|go:"GO:0046940"(nucleoside monophosphate phosphorylation)|interpro:IPR000850(Adenylate kinase)|interpro:IPR006259(Adenylate kinase, subfamily)|interpro:IPR007862(Adenylate kinase, zinc-finger lid region)|interpro:IPR028586|interpro:IPR033690|interpro:IPR036193|mint:Q9UIJ7|rcsb pdb:1ZD8|rcsb pdb:6ZJB|rcsb pdb:6ZJD|rcsb pdb:6ZJE|reactome:R-HSA-983231|interpro:IPR027417 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:NDt9xiBjW8L9uXYnyZhVYpVybfA9606 rigid:kSYNWJcKrJbUfiz+ajQ6iyKLmVM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:P53779 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-713543|uniprotkb:A6NFS3|uniprotkb:Q15707|uniprotkb:Q49AP1|uniprotkb:A6NG28|uniprotkb:B3KQ94|ensembl:ENSP00000424154|ensembl:ENSP00000492204|ensembl:ENSP00000492292|ensembl:ENSP00000492903|ensembl:ENSP00000493013|ensembl:ENSP00000493045|ensembl:ENSP00000493072|ensembl:ENSP00000493275|ensembl:ENSP00000493290|ensembl:ENSP00000493363|ensembl:ENSP00000493375|ensembl:ENSP00000493408|ensembl:ENSP00000493435|ensembl:ENSP00000493450 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:mk10_human(display_long)|uniprotkb:Stress-activated protein kinase JNK3(gene name synonym)|uniprotkb:c-Jun N-terminal kinase 3(gene name synonym)|uniprotkb:MAP kinase p49 3F12(gene name synonym)|uniprotkb:MAPK10(gene name)|psi-mi:MAPK10(display_short)|uniprotkb:JNK3(gene name synonym)|uniprotkb:JNK3A(gene name synonym)|uniprotkb:PRKM10(gene name synonym)|uniprotkb:Stress-activated protein kinase 1b(gene name synonym)|uniprotkb:SAPK1B(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288483|imex:IM-26899-315 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 refseq:XP_006714331.1|refseq:XP_005263186.1|refseq:XP_005263187.1|refseq:XP_005263192.1|refseq:NP_002744.1|refseq:NP_620446.1|refseq:NP_620448.1|refseq:NP_001304996.1|refseq:NP_001304997.1|refseq:NP_001304998.1|refseq:XP_011530419.1|refseq:XP_011530420.1|refseq:XP_011530422.1|refseq:XP_011530423.1|refseq:XP_016863908.1|refseq:XP_016863909.1|refseq:XP_016863910.1|refseq:XP_016863912.1|refseq:XP_016863913.1|refseq:XP_016863914.1|refseq:XP_016863915.1|refseq:XP_016863918.1|refseq:XP_016863919.1|refseq:XP_016863920.1|refseq:XP_016863921.1|dip:DIP-1015N|ensembl:ENSG00000109339(gene)|ensembl:ENST00000515400(transcript)|ensembl:ENST00000515650(transcript)|ensembl:ENST00000638313(transcript)|ensembl:ENST00000641051(transcript)|ensembl:ENST00000641066(transcript)|ensembl:ENST00000641157(transcript)|ensembl:ENST00000641207(transcript)|ensembl:ENST00000641341(transcript)|ensembl:ENST00000641462(transcript)|ensembl:ENST00000641647(transcript)|ensembl:ENST00000641823(transcript)|ensembl:ENST00000641902(transcript)|ensembl:ENST00000641952(transcript)|ensembl:ENST00000641983(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004705"(JUN kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007254"(JNK cascade)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009416"(response to light stimulus)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0048511"(rhythmic process)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0090398"(cellular senescence)|go:"GO:0098969"(neurotransmitter receptor transport to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008351(JNK MAP kinase)|interpro:IPR011009(Protein kinase-like)|mint:P53779|rcsb pdb:1JNK|rcsb pdb:1PMN|rcsb pdb:1PMU|rcsb pdb:1PMV|rcsb pdb:2B1P|rcsb pdb:2EXC|rcsb pdb:2O0U|rcsb pdb:2O2U|rcsb pdb:2OK1|rcsb pdb:2P33|rcsb pdb:2R9S|rcsb pdb:2WAJ|rcsb pdb:2ZDT|rcsb pdb:2ZDU|rcsb pdb:3CGF|rcsb pdb:3CGO|rcsb pdb:3DA6|rcsb pdb:3FI2|rcsb pdb:3FI3|rcsb pdb:3FV8|rcsb pdb:3G90|rcsb pdb:3G9L|rcsb pdb:3G9N|rcsb pdb:3KVX|rcsb pdb:3OXI|rcsb pdb:3OY1|rcsb pdb:3PTG|rcsb pdb:3RTP|rcsb pdb:3TTI|rcsb pdb:3TTJ|rcsb pdb:3V6R|rcsb pdb:3V6S|rcsb pdb:4H36|rcsb pdb:4H39|rcsb pdb:4H3B|rcsb pdb:4KKE|rcsb pdb:4KKG|rcsb pdb:4KKH|rcsb pdb:4U79|rcsb pdb:4W4V|rcsb pdb:4W4W|rcsb pdb:4W4X|rcsb pdb:4W4Y|rcsb pdb:4WHZ|rcsb pdb:4X21|rcsb pdb:4Y46|rcsb pdb:4Y5H|rcsb pdb:4Z9L|rcsb pdb:6EKD|rcsb pdb:6EMH|rcsb pdb:6EQ9|rcsb pdb:7KSI|rcsb pdb:7KSJ|rcsb pdb:7KSK|reactome:R-HSA-2559580|reactome:R-HSA-2871796|reactome:R-HSA-450321|reactome:R-HSA-450341 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:dzYzsLACbyCktFnxNeBXEf02BdA9606 rigid:+NdfihVfGv2hJAD3SwTEV6aPNV4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:Q0VDF9 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-8773684|uniprotkb:A8K8F8|uniprotkb:B0YIY9|uniprotkb:Q9P0X2|uniprotkb:Q9UI07|ensembl:ENSP00000367623 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:hsp7e_human(display_long)|uniprotkb:HSPA14(gene name)|psi-mi:HSPA14(display_short)|uniprotkb:HSP60(gene name synonym)|uniprotkb:HSP70L1(gene name synonym)|uniprotkb:HSP70-like protein 1(gene name synonym)|uniprotkb:Heat shock protein HSP60(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288477|imex:IM-26899-435 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 refseq:NP_057383.2|ensembl:ENSG00000187522(gene)|ensembl:ENST00000378372(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051083"('de novo' cotranslational protein folding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR042049|interpro:IPR043129|mint:Q0VDF9|reactome:R-HSA-3371453|dip:DIP-62114N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:RNKKz93Uww+GkRXdvnm5QY8h+lM9606 rigid:FWVbS9yMvt6dQY1NN+DxLig0E6Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:Q9UBP4 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-954409|ensembl:ENSP00000314910|ensembl:ENSP00000379762|ensembl:ENSP00000506835|uniprotkb:Q9ULB7|uniprotkb:A8K1I2|uniprotkb:D3DQW1 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:dkk3_human(display_long)|uniprotkb:REIC(gene name synonym)|uniprotkb:UNQ258/PRO295(orf name)|uniprotkb:DKK3(gene name)|psi-mi:DKK3(display_short) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288471|imex:IM-26899-115 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 ensembl:ENSG00000050165(gene)|ensembl:ENST00000326932(transcript)|ensembl:ENST00000396505(transcript)|ensembl:ENST00000683431(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030325"(adrenal gland development)|go:"GO:0032348"(negative regulation of aldosterone biosynthetic process)|go:"GO:0039706"(co-receptor binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1902613"(negative regulation of anti-Mullerian hormone signaling pathway)|go:"GO:2000065"(negative regulation of cortisol biosynthetic process)|interpro:IPR006796(Dickkopf, N-terminal cysteine-rich)|interpro:IPR039863|mint:Q9UBP4|refseq:NP_001018067.1|refseq:NP_037385.2|refseq:NP_056965.3|refseq:XP_006718241.1|refseq:NP_001317149.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:pnbEZP5fAWw3Qxg1gB1sjP0Oyeo9606 rigid:iTJLNNhnsXsWJWxA0SJo2IMGk30 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:Q14562 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-2511477|ensembl:ENSP00000262415|ensembl:ENSP00000496923 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:dhx8_human(display_long)|uniprotkb:DHX8(gene name)|psi-mi:DHX8(display_short)|uniprotkb:DDX8(gene name synonym)|uniprotkb:DEAH box protein 8(gene name synonym)|uniprotkb:RNA helicase HRH1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288465|imex:IM-26899-207 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 mint:Q14562|rcsb pdb:2EQS|rcsb pdb:3I4U|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:6HYS|rcsb pdb:6HYT|rcsb pdb:6HYU|rcsb pdb:6ICZ|rcsb pdb:6QDV|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0000398"(mRNA splicing, via spliceosome)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR003029(S1, RNA binding)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR022967|interpro:IPR027417|interpro:IPR044762|ensembl:ENSG00000067596(gene)|ensembl:ENST00000262415(transcript)|ensembl:ENST00000650571(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|refseq:NP_004932.1|refseq:NP_001289552.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:ZUmh+KApFNV5NKCq6dizDgnw/Dw9606 rigid:9YBxwe3yUftBuztZR3DQVvIQPMI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:Q8NCW5 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-2564619|uniprotkb:B4DGY3|uniprotkb:Q496C6|uniprotkb:Q5T3I2|ensembl:ENSP00000357218|ensembl:ENSP00000505349|ensembl:ENSP00000505899|ensembl:ENSP00000505913|ensembl:ENSP00000506192|ensembl:ENSP00000506275 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:nnre_human(display_long)|uniprotkb:NAXE(gene name)|psi-mi:NAXE(display_short)|uniprotkb:AIBP(gene name synonym)|uniprotkb:APOA1BP(gene name synonym)|uniprotkb:Apolipoprotein A-I-binding protein(gene name synonym)|uniprotkb:"NAD(P)HX epimerase"(gene name synonym)|uniprotkb:YJEFN1(gene name synonym)|uniprotkb:YjeF N-terminal domain-containing protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288459|imex:IM-26899-735 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 refseq:NP_658985.2|ensembl:ENST00000679702(transcript)|ensembl:ENST00000680004(transcript)|ensembl:ENST00000680269(transcript)|ensembl:ENST00000681054(transcript)|ensembl:ENST00000681523(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005929"(cilium)|go:"GO:0006869"(lipid transport)|go:"GO:0010874"(regulation of cholesterol efflux)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0031580"(membrane raft distribution)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0046496"(nicotinamide nucleotide metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0052856"(NADHX epimerase activity)|go:"GO:0052857"(NADPHX epimerase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004443(YjeF-related protein, N-terminal)|interpro:IPR032976|interpro:IPR036652|mint:Q8NCW5|reactome:R-HSA-197264|ensembl:ENSG00000163382(gene)|ensembl:ENST00000368235(transcript) - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:Sbye6Tfjl+zVbAgoFH2zdfqe3709606 rigid:7l1sDHaF59xQ8pdpzVoyZhcM6F8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:O43396 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-1048857|ensembl:ENSP00000217515|ensembl:ENSP00000464918 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:txnl1_human(display_long)|uniprotkb:32 kDa thioredoxin-related protein(gene name synonym)|uniprotkb:TXNL1(gene name)|psi-mi:TXNL1(display_short)|uniprotkb:TRP32(gene name synonym)|uniprotkb:TXL(gene name synonym)|uniprotkb:TXNL(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288489|imex:IM-26899-837 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 refseq:NP_004777.1|ensembl:ENSG00000091164(gene)|ensembl:ENST00000217515(transcript)|ensembl:ENST00000590954(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015036"(disulfide oxidoreductase activity)|interpro:IPR008979(Galactose-binding like)|interpro:IPR010400(Protein of unknown function DUF1000)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|interpro:IPR037047|mint:O43396|rcsb pdb:1GH2|rcsb pdb:1WWY|reactome:R-HSA-9013418|reactome:R-HSA-9013420|reactome:R-HSA-9013422|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:XP_016881582.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:v3qpLTWgZZ1f4Tz/ixVYlSPv7Ro9606 rigid:HDvvd31/ErzVuSKv1Gx+8dHd3L4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A33 uniprotkb:Q9H0F5 intact:EBI-21286457|ensemblbacteria:AAO91562 intact:EBI-2341200|uniprotkb:Q8N0Y0|uniprotkb:A6PVP9|uniprotkb:B1AM82|uniprotkb:Q7LB33|ensembl:ENSP00000259605|uniprotkb:B1AM81|uniprotkb:B3KSG4|uniprotkb:E7EVL3|uniprotkb:Q9H748 psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:rnf38_human(display_long)|uniprotkb:RING finger protein 38(gene name synonym)|uniprotkb:RNF38(gene name)|psi-mi:RNF38(display_short)|uniprotkb:RING-type E3 ubiquitin transferase RNF38(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288501|imex:IM-26899-437 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 refseq:XP_011516014.1|refseq:XP_011516015.1|refseq:XP_006716784.1|refseq:NP_073618.3|refseq:NP_919309.1|refseq:NP_919310.1|refseq:NP_919311.1|refseq:NP_919313.1|ensembl:ENSG00000137075(gene)|ensembl:ENST00000259605(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008584"(male gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|go:"GO:0036126"(sperm flagellum)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q9H0F5|rcsb pdb:1X4J|rcsb pdb:4V3K|rcsb pdb:4V3L|ensembl:ENSP00000259605|ensembl:ENST00000350199|ensembl:ENSP00000343947|ensembl:ENST00000353739|ensembl:ENSP00000335239|ensembl:ENST00000357058|ensembl:ENSP00000349566|ensembl:ENST00000377877|ensembl:ENSP00000367109|ensembl:ENST00000377885|ensembl:ENSP00000367117|ensembl:ENST00000611646|ensembl:ENSP00000483536|refseq:XP_005251423.1|refseq:XP_005251424.1|refseq:XP_005251425.1|refseq:XP_016869784.1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rogid:leJgsTFAtsRhHPh44pbrpk1wkDo9606 rigid:BJicUcaEQyoCjLBfcjejDFmBLnk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A33 uniprotkb:O00399 intact:EBI-21286457|ensemblbacteria:AAO91562 intact:EBI-2559415|uniprotkb:B2RAC1|ensembl:ENSP00000221114 psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:dctn6_human(display_long)|uniprotkb:DCTN6(gene name)|psi-mi:DCTN6(display_short)|uniprotkb:WS3(gene name synonym)|uniprotkb:Dynactin subunit p27(gene name synonym)|uniprotkb:Protein WS-3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288495|imex:IM-26899-635 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 refseq:NP_006562.1|ensembl:ENSG00000104671(gene)|ensembl:ENST00000221114(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0070840"(dynein complex binding)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR027777|mint:O00399|rcsb pdb:3TV0|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rogid:+35O26TEIL5l1I7XrNJcl6BA77c9606 rigid:sqWORM+nQHm1D/7ovttVOd/5+x0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A33 uniprotkb:Q8TAF3 intact:EBI-21286457|ensemblbacteria:AAO91562 intact:EBI-1045469|uniprotkb:Q63HJ2|uniprotkb:Q658Y1|uniprotkb:Q8N3Z1|uniprotkb:Q9NSK8|uniprotkb:Q9P279|uniprotkb:B4DM86|uniprotkb:B4DQI2|uniprotkb:B4DY84|ensembl:ENSP00000307491 psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:wdr48_human(display_long)|uniprotkb:WD repeat endosomal protein(gene name synonym)|uniprotkb:p80(gene name synonym)|uniprotkb:WDR48(gene name)|psi-mi:WDR48(display_short)|uniprotkb:KIAA1449(gene name synonym)|uniprotkb:UAF1(gene name synonym)|uniprotkb:USP1-associated factor 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288507|imex:IM-26899-637 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 refseq:NP_065890.1|ensembl:ENSG00000114742(gene)|ensembl:ENST00000302313(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043588"(skin development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1902525"(regulation of protein monoubiquitination)|go:"GO:1903003"(positive regulation of protein deubiquitination)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021772|interpro:IPR036322|mint:Q8TAF3|rcsb pdb:5CVL|rcsb pdb:5CVN|rcsb pdb:5CVO|rcsb pdb:5K1A|rcsb pdb:5K1B|rcsb pdb:5K1C|rcsb pdb:5L8E|rcsb pdb:5L8W|rcsb pdb:6JLQ|rcsb pdb:7AY0|rcsb pdb:7AY1|rcsb pdb:7AY2|reactome:R-HSA-110314|reactome:R-HSA-5689880|reactome:R-HSA-6783310|reactome:R-HSA-9673766|refseq:NP_001290331.1|refseq:NP_001290332.1|refseq:NP_001333156.1|refseq:NP_001333157.1|dip:DIP-50841N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rogid:S8ihl3jxEEyMS46AM2ynXSFfCU49606 rigid:x8n86EoLhVAxPifCn3xVbYXUAF4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A11 uniprotkb:Q0VDF9 intact:EBI-21286600|ensemblbacteria:AAO91591 intact:EBI-8773684|uniprotkb:A8K8F8|uniprotkb:B0YIY9|uniprotkb:Q9P0X2|uniprotkb:Q9UI07|ensembl:ENSP00000367623 psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name) psi-mi:hsp7e_human(display_long)|uniprotkb:HSPA14(gene name)|psi-mi:HSPA14(display_short)|uniprotkb:HSP60(gene name synonym)|uniprotkb:HSP70L1(gene name synonym)|uniprotkb:HSP70-like protein 1(gene name synonym)|uniprotkb:Heat shock protein HSP60(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288513|imex:IM-26899-839 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91591(transcript)|ensemblbacteria:CBUA0014(gene)|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047|mint:Q83A11 refseq:NP_057383.2|ensembl:ENSG00000187522(gene)|ensembl:ENST00000378372(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051083"('de novo' cotranslational protein folding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR042049|interpro:IPR043129|mint:Q0VDF9|reactome:R-HSA-3371453|dip:DIP-62114N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377 rogid:RNKKz93Uww+GkRXdvnm5QY8h+lM9606 rigid:0kzJz0Zm2yCo6PT+HLT9rNx32YM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A11 uniprotkb:O75970 intact:EBI-21286600|ensemblbacteria:AAO91591 intact:EBI-821405|intact:EBI-2684724|uniprotkb:Q4LE30|uniprotkb:B7ZMI4|uniprotkb:A6NLC2|uniprotkb:O43798|uniprotkb:Q5CZ80|uniprotkb:Q5JTX3|uniprotkb:Q5JTX6|uniprotkb:Q5JTX7|uniprotkb:Q5JUC3|uniprotkb:Q5JUC4|uniprotkb:Q5VZ62|uniprotkb:Q8N790|intact:EBI-10961605|uniprotkb:B2RTS3|ensembl:ENSP00000320006 psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name) psi-mi:mpdz_human(display_long)|uniprotkb:Multi-PDZ domain protein 1(gene name synonym)|uniprotkb:MPDZ(gene name)|psi-mi:MPDZ(display_short)|uniprotkb:MUPP1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288519|imex:IM-26899-841 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91591(transcript)|ensemblbacteria:CBUA0014(gene)|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047|mint:Q83A11 refseq:XP_006716948.1|refseq:XP_006716949.1|refseq:XP_006716950.1|refseq:XP_006716951.1|refseq:XP_006716952.1|refseq:XP_006716954.1|refseq:NP_003820.2|refseq:NP_001248335.1|refseq:NP_001248336.1|refseq:NP_001317566.1|refseq:XP_016870742.1|ensembl:ENSG00000107186(gene)|ensembl:ENST00000319217(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0030425"(dendrite)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR032078|interpro:IPR036034|interpro:IPR036892|mint:O75970|rcsb pdb:2FCF|rcsb pdb:2FNE|rcsb pdb:2IWN|rcsb pdb:2IWO|rcsb pdb:2IWP|rcsb pdb:2IWQ|rcsb pdb:2O2T|rcsb pdb:2OPG|rcsb pdb:2QG1 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377 rogid:Q5QzIDHLoL/sWqQI7r/Kb4VLSdY9606 rigid:TazseQ3p2rSrJzT8JyTpcPzlu1A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y320 uniprotkb:Q83A11 intact:EBI-6447886|ensembl:ENSP00000278422|uniprotkb:B7Z4R4|uniprotkb:Q8NBP9|uniprotkb:Q5J7Q7|uniprotkb:Q561W0|uniprotkb:Q53G73|uniprotkb:Q9H3L1|intact:EBI-7128726|intact:MINT-6945923 intact:EBI-21286600|ensemblbacteria:AAO91591 psi-mi:tmx2_human(display_long)|uniprotkb:Cell proliferation-inducing gene 26 protein(gene name synonym)|uniprotkb:TXNDC14(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 14(gene name synonym)|uniprotkb:CGI-31(orf name)|uniprotkb:My009(orf name)|uniprotkb:PIG26(orf name)|uniprotkb:PSEC0045(orf name)|uniprotkb:UNQ237/PRO270(orf name)|uniprotkb:TMX2(gene name)|psi-mi:TMX2(display_short) psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288525|imex:IM-26899-209 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000213593(gene)|ensembl:ENST00000278422(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007420"(brain development)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043227"(membrane-bounded organelle)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR037463|interpro:IPR039101|mint:Q9Y320|rcsb pdb:2DJ0|refseq:NP_001137484.1|refseq:NP_057043.1 ensemblbacteria:AAO91591(transcript)|ensemblbacteria:CBUA0014(gene)|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047|mint:Q83A11 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:5YbR806GhogQ2yI3r9uo8i97MzY9606 rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377 rigid:A8yf6pgm50AAh4o4ZA118lqcwf4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A11 uniprotkb:O75436 intact:EBI-21286600|ensemblbacteria:AAO91591 intact:EBI-1043891|uniprotkb:Q8TBH4|uniprotkb:Q9H982|ensembl:ENSP00000263559|ensembl:ENSP00000362480|uniprotkb:B2RDD3|uniprotkb:A8MZ56 psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name) psi-mi:vp26a_human(display_long)|uniprotkb:VPS26A(gene name)|psi-mi:VPS26A(display_short)|uniprotkb:VPS26(gene name synonym)|uniprotkb:Vesicle protein sorting 26A(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288531|imex:IM-26899-737 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91591(transcript)|ensemblbacteria:CBUA0014(gene)|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047|mint:Q83A11 ensembl:ENSG00000122958(gene)|ensembl:ENST00000263559(transcript)|ensembl:ENST00000373382(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031982"(vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0097422"(tubular endosome)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR028934|mint:O75436|rcsb pdb:2FAU|rcsb pdb:5F0J|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|reactome:R-HSA-3238698|rcsb pdb:7BLO|refseq:NP_001030337.1|refseq:NP_004887.2|refseq:NP_001305875.1|dip:DIP-29075N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377 rogid:n0uOd+2HQmRW7koIy678uP0d3+o9606 rigid:jFYYeg4AjlMzUhaMh8yGB1OcyU8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A11 uniprotkb:Q8TAF3 intact:EBI-21286600|ensemblbacteria:AAO91591 intact:EBI-1045469|uniprotkb:Q63HJ2|uniprotkb:Q658Y1|uniprotkb:Q8N3Z1|uniprotkb:Q9NSK8|uniprotkb:Q9P279|uniprotkb:B4DM86|uniprotkb:B4DQI2|uniprotkb:B4DY84|ensembl:ENSP00000307491 psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name) psi-mi:wdr48_human(display_long)|uniprotkb:WD repeat endosomal protein(gene name synonym)|uniprotkb:p80(gene name synonym)|uniprotkb:WDR48(gene name)|psi-mi:WDR48(display_short)|uniprotkb:KIAA1449(gene name synonym)|uniprotkb:UAF1(gene name synonym)|uniprotkb:USP1-associated factor 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288537|imex:IM-26899-317 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91591(transcript)|ensemblbacteria:CBUA0014(gene)|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047|mint:Q83A11 refseq:NP_065890.1|ensembl:ENSG00000114742(gene)|ensembl:ENST00000302313(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043588"(skin development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1902525"(regulation of protein monoubiquitination)|go:"GO:1903003"(positive regulation of protein deubiquitination)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021772|interpro:IPR036322|mint:Q8TAF3|rcsb pdb:5CVL|rcsb pdb:5CVN|rcsb pdb:5CVO|rcsb pdb:5K1A|rcsb pdb:5K1B|rcsb pdb:5K1C|rcsb pdb:5L8E|rcsb pdb:5L8W|rcsb pdb:6JLQ|rcsb pdb:7AY0|rcsb pdb:7AY1|rcsb pdb:7AY2|reactome:R-HSA-110314|reactome:R-HSA-5689880|reactome:R-HSA-6783310|reactome:R-HSA-9673766|refseq:NP_001290331.1|refseq:NP_001290332.1|refseq:NP_001333156.1|refseq:NP_001333157.1|dip:DIP-50841N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/15 rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377 rogid:S8ihl3jxEEyMS46AM2ynXSFfCU49606 rigid:MD+VMM+Xjaa41NKEwpbePvTPaWs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:P63037 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-772408|uniprotkb:P54102|ensembl:ENSMUSP00000030118|ensembl:ENSMUSP00000129730 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:dnja1_mouse(display_long)|uniprotkb:Heat shock 40 kDa protein 4(gene name synonym)|uniprotkb:DnaJ protein homolog 2(gene name synonym)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:Dnaja1(gene name)|psi-mi:Dnaja1(display_short)|uniprotkb:Dnaj2(gene name synonym)|uniprotkb:Hsj2(gene name synonym)|uniprotkb:Hspf4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288583|imex:IM-26899-559 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 refseq:NP_001158143.1|refseq:NP_001158144.1|refseq:NP_032324.1|dip:DIP-32350N|ensembl:ENSMUSG00000028410(gene)|ensembl:ENSMUST00000030118(transcript)|ensembl:ENSMUST00000164233(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009408"(response to heat)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:1901998"(toxin transport)|go:"GO:1903748"(negative regulation of establishment of protein localization to mitochondrion)|go:"GO:1905259"(negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:P63037|reactome:R-MMU-3371497 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/24 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:gi42F7LF6CiylXZF4fRg/kuM/s010090 rigid:zqxuLsO7ypyp5loj/A2BQJxF2qg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A11 uniprotkb:Q9WTX5 intact:EBI-21286600|ensemblbacteria:AAO91591 intact:EBI-1202363|uniprotkb:Q8C5H6|ensembl:ENSMUSP00000038744|ensembl:ENSMUSP00000104700 psi-mi:q83a11_coxbu(display_long)|uniprotkb:CBUA0014(locus name) psi-mi:skp1_mouse(display_long)|uniprotkb:Skp1(gene name)|psi-mi:Skp1(display_short)|uniprotkb:Skp1a(gene name synonym)|uniprotkb:S-phase kinase-associated protein 1A(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:p19A(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288649|imex:IM-26899-739 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91591(transcript)|ensemblbacteria:CBUA0014(gene)|refseq:NP_819031.1|refseq:WP_011109640.1|interpro:IPR036047|mint:Q83A11 refseq:NP_035673.3|refseq:XP_006532849.1|go:"GO:0019904"(protein domain specific binding)|ensembl:ENSMUSG00000036309(gene)|ensembl:ENSMUST00000037324(transcript)|ensembl:ENSMUST00000109072(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:Q9WTX5|reactome:R-MMU-1169091|reactome:R-MMU-1170546|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2565942|reactome:R-MMU-2871837|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5676590|reactome:R-MMU-5684264|reactome:R-MMU-68949|reactome:R-MMU-69231|reactome:R-MMU-8854050|reactome:R-MMU-8939902|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-917937|reactome:R-MMU-9708530|reactome:R-MMU-983168|dip:DIP-38596N - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/24 rogid:g1c/rJdaqBwTQqymFN4nG7ZbSzA227377 rogid:qGk720KMKAbBPguy2tmUOZsLxRQ10090 rigid:kByXQOMRvc7UEWAkTP8ftAiT7z4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q8C0M9 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-2308217|uniprotkb:Q91WC8|uniprotkb:Q9CVX3|ensembl:ENSMUSP00000051709 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:asgl1_mouse(display_long)|uniprotkb:Beta-aspartyl-peptidase(gene name synonym)|uniprotkb:Isoaspartyl dipeptidase(gene name synonym)|uniprotkb:Asrgl1(gene name)|psi-mi:Asrgl1(display_short)|uniprotkb:L-asparagine amidohydrolase(gene name synonym)|uniprotkb:Asparaginase-like protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288553|imex:IM-26899-117 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_079886.2|ensembl:ENSMUSG00000024654(gene)|ensembl:ENSMUST00000049948(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0004067"(asparaginase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0008798"(beta-aspartyl-peptidase activity)|go:"GO:0033345"(asparagine catabolic process via L-aspartate)|interpro:IPR000246(Peptidase T2, asparaginase 2)|interpro:IPR029055|interpro:IPR033844|mint:Q8C0M9|reactome:R-MMU-8964208 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/24 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:wiexavwMdQbxSvFKT3feeH1J0+010090 rigid:ccP0Wk81nw4zSij2GuB6nL+n0nU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:Q7TQI3 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-2309876|uniprotkb:Q3ULV9|uniprotkb:Q3V408|uniprotkb:Q8C326|uniprotkb:Q8R5F2|ensembl:ENSMUSP00000025679 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:otub1_mouse(display_long)|uniprotkb:Otub1(gene name)|psi-mi:Otub1(display_short)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288599|imex:IM-26899-319 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 refseq:NP_598911.1|ensembl:ENSMUSG00000024767(gene)|ensembl:ENSMUST00000025679(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q7TQI3|reactome:R-MMU-5689880|reactome:R-MMU-5689896 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/24 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:8wyAgdbYnbsj8QYkhuruP2tdw5Q10090 rigid:1rbEs/vLGRBBh2UP7tSdJvK5XBM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:Q8K298 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-2553580|uniprotkb:Q8BL79|uniprotkb:Q8BLB3|uniprotkb:Q9CUY0|uniprotkb:Q8K2N0|ensembl:ENSMUSP00000045873 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:anln_mouse(display_long)|uniprotkb:Anln(gene name)|psi-mi:Anln(display_short) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288567|imex:IM-26899-215 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 ensembl:ENSMUSG00000036777(gene)|ensembl:ENSMUST00000040912(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030496"(midbody)|go:"GO:0031106"(septin ring organization)|go:"GO:0032059"(bleb)|go:"GO:0090521"(glomerular visceral epithelial cell migration)|go:"GO:0099738"(cell cortex region)|go:"GO:1904172"(positive regulation of bleb assembly)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012966(Protein of unknown function DUF1709, fungi)|interpro:IPR031970|interpro:IPR037840|mint:Q8K298|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|refseq:NP_082666.2 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/24 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:EO+oGgohw0Ee5W3sDVXSpfF29dA10090 rigid:KBjtfTwfug79cr8/uzBktSkSqfc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83B01 uniprotkb:Q9ERF3 intact:EBI-21286307|ensemblbacteria:AAO91219 intact:EBI-6094557|uniprotkb:Q3U562|uniprotkb:Q9CZP1|ensembl:ENSMUSP00000056359|ensembl:ENSMUSP00000113560 psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:wdr61_mouse(display_long)|uniprotkb:Wdr61(gene name)|psi-mi:Wdr61(display_short)|uniprotkb:Meiotic recombination REC14 protein homolog(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288607|imex:IM-26899-843 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 refseq:NP_001020546.1|refseq:NP_075680.1|ensembl:ENSMUSG00000061559(gene)|ensembl:ENSMUST00000051822(transcript)|ensembl:ENSMUST00000121204(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0055087"(Ski complex)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9ERF3|reactome:R-MMU-112382|reactome:R-MMU-429958|reactome:R-MMU-674695|reactome:R-MMU-75955|reactome:R-MMU-8866654 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/24 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rogid:r5TxJiuiFNk5dUDuhzCqFfFXX/M10090 rigid:FuGqbP+ER1YO1TAXVe6D3HuaJtw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83A33 uniprotkb:Q9ERF3 intact:EBI-21286457|ensemblbacteria:AAO91562 intact:EBI-6094557|uniprotkb:Q3U562|uniprotkb:Q9CZP1|ensembl:ENSMUSP00000056359|ensembl:ENSMUSP00000113560 psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:wdr61_mouse(display_long)|uniprotkb:Wdr61(gene name)|psi-mi:Wdr61(display_short)|uniprotkb:Meiotic recombination REC14 protein homolog(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288641|imex:IM-26899-219 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 refseq:NP_001020546.1|refseq:NP_075680.1|ensembl:ENSMUSG00000061559(gene)|ensembl:ENSMUST00000051822(transcript)|ensembl:ENSMUST00000121204(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0055087"(Ski complex)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9ERF3|reactome:R-MMU-112382|reactome:R-MMU-429958|reactome:R-MMU-674695|reactome:R-MMU-75955|reactome:R-MMU-8866654 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/24 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rogid:r5TxJiuiFNk5dUDuhzCqFfFXX/M10090 rigid:8tBQmZLwF7YeNmpgP9UnFt10bZ4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83D60 uniprotkb:Q9CZQ9 intact:EBI-21285556|ensemblbacteria:AAO90413 intact:EBI-6127679|uniprotkb:A2AUC7|ensembl:ENSMUSP00000074494 psi-mi:q83d60_coxbu(display_long)|uniprotkb:CBU_0881(locus name) psi-mi:bbs5_mouse(display_long)|uniprotkb:Bbs5(gene name)|psi-mi:Bbs5(display_short) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288559|imex:IM-26899-213 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90413(transcript)|ensemblbacteria:CBU_0881(gene)|refseq:NP_819899.1|refseq:WP_010957865.1|mint:Q83D60 refseq:NP_082560.1|ensembl:ENSMUSG00000063145(gene)|ensembl:ENSMUST00000074963(transcript)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0015031"(protein transport)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034464"(BBSome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0046907"(intracellular transport)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR006606(Protein of unknown function DUF1448)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014003(Protein of unknown function DM16)|interpro:IPR030804|mint:Q9CZQ9|reactome:R-MMU-5620922 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/24 rogid:lOFXL6FTaPWVEUAliVyW9Tl6HSA227377 rogid:tpfXPd3gpQIC6+kp3OOpwiXrZe810090 rigid:dyt6D/sUyJESdvEbY7++GXG6kyE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q83DE4 uniprotkb:Q9CZQ9 intact:EBI-21285423|ensemblbacteria:AAO90328 intact:EBI-6127679|uniprotkb:A2AUC7|ensembl:ENSMUSP00000074494 psi-mi:q83de4_coxbu(display_long)|uniprotkb:CBU_0794(locus name) psi-mi:bbs5_mouse(display_long)|uniprotkb:Bbs5(gene name)|psi-mi:Bbs5(display_short) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288545|imex:IM-26899-211 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAO90328(transcript)|ensemblbacteria:CBU_0794(gene)|refseq:NP_819814.1|refseq:WP_010957806.1|mint:Q83DE4 refseq:NP_082560.1|ensembl:ENSMUSG00000063145(gene)|ensembl:ENSMUST00000074963(transcript)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0015031"(protein transport)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034464"(BBSome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0046907"(intracellular transport)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR006606(Protein of unknown function DUF1448)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014003(Protein of unknown function DM16)|interpro:IPR030804|mint:Q9CZQ9|reactome:R-MMU-5620922 - - - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/24 rogid:XVA7R483yYdpYkhCnAqOzU8u000227377 rogid:tpfXPd3gpQIC6+kp3OOpwiXrZe810090 rigid:NDO2dKTievhPk0qo0SC1RqxyqOA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3TDX8 uniprotkb:Q83A33 intact:EBI-7928047|uniprotkb:Q6VXY4|uniprotkb:Q8BTI5|uniprotkb:Q3U012|uniprotkb:Q8BJV8|intact:UNK-5537179|uniprotkb:Q3TJH3|uniprotkb:Q6VXY5|uniprotkb:E9Q129|uniprotkb:Q8R3H8|uniprotkb:Q99LY4|uniprotkb:Q99P29|ensembl:ENSMUSP00000126119 intact:EBI-21286457|ensemblbacteria:AAO91562 psi-mi:nb5r4_mouse(display_long)|uniprotkb:Cyb5r4(gene name)|psi-mi:Cyb5r4(display_short)|uniprotkb:Ncb5or(gene name synonym)|uniprotkb:Flavohemoprotein b5/b5R(gene name synonym)|uniprotkb:cb5/cb5R(gene name synonym)|uniprotkb:N-terminal cytochrome b5 and cytochrome b5 oxidoreductase domain-containing protein(gene name synonym) psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288613|imex:IM-26899-119 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077157.2|refseq:XP_006511262.1|ensembl:ENSMUSG00000032872(gene)|ensembl:ENSMUST00000168529(transcript)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0004128"("cytochrome-b5 reductase activity, acting on NAD(P)H")|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006739"(NADP metabolic process)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016653"("oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor")|go:"GO:0020037"(heme binding)|interpro:IPR001199(Cytochrome b5)|go:"GO:0030073"(insulin secretion)|go:"GO:0042168"(heme metabolic process)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0046677"(response to antibiotic)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001834("NADH:cytochrome b5 reductase (CBR)")|interpro:IPR007052(CS domain)|interpro:IPR008333(Oxidoreductase FAD-binding region)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR017927|interpro:IPR017938|interpro:IPR018506|interpro:IPR036400|interpro:IPR037908|interpro:IPR039261|mint:Q3TDX8|reactome:R-MMU-1237044|go:"GO:0046872"(metal ion binding)|go:"GO:0048468"(cell development)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0072593"(reactive oxygen species metabolic process) ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 - comment:mint|function:"NADH-cytochrome b5 reductase involved in endolasmic reticulum stress response pathway. Plays a critical role in protecting pancreatic beta-cells against oxidant stress, possibly by protecting the cell from excess buildup of reactive oxygen species (ROS)" - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/24 rogid:j19wK584v3ZVxPwALGRiJ1DnnvU10090 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rigid:PL1bI6LzqCvh5OSzuvp/nA5qm70 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3TDX8 uniprotkb:Q83B01 intact:EBI-7928047|uniprotkb:Q6VXY4|uniprotkb:Q8BTI5|uniprotkb:Q3U012|uniprotkb:Q8BJV8|intact:UNK-5537179|uniprotkb:Q3TJH3|uniprotkb:Q6VXY5|uniprotkb:E9Q129|uniprotkb:Q8R3H8|uniprotkb:Q99LY4|uniprotkb:Q99P29|ensembl:ENSMUSP00000126119 intact:EBI-21286307|ensemblbacteria:AAO91219 psi-mi:nb5r4_mouse(display_long)|uniprotkb:Cyb5r4(gene name)|psi-mi:Cyb5r4(display_short)|uniprotkb:Ncb5or(gene name synonym)|uniprotkb:Flavohemoprotein b5/b5R(gene name synonym)|uniprotkb:cb5/cb5R(gene name synonym)|uniprotkb:N-terminal cytochrome b5 and cytochrome b5 oxidoreductase domain-containing protein(gene name synonym) psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288575|imex:IM-26899-439 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077157.2|refseq:XP_006511262.1|ensembl:ENSMUSG00000032872(gene)|ensembl:ENSMUST00000168529(transcript)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0004128"("cytochrome-b5 reductase activity, acting on NAD(P)H")|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006739"(NADP metabolic process)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016653"("oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor")|go:"GO:0020037"(heme binding)|interpro:IPR001199(Cytochrome b5)|go:"GO:0030073"(insulin secretion)|go:"GO:0042168"(heme metabolic process)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0046677"(response to antibiotic)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001834("NADH:cytochrome b5 reductase (CBR)")|interpro:IPR007052(CS domain)|interpro:IPR008333(Oxidoreductase FAD-binding region)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR017927|interpro:IPR017938|interpro:IPR018506|interpro:IPR036400|interpro:IPR037908|interpro:IPR039261|mint:Q3TDX8|reactome:R-MMU-1237044|go:"GO:0046872"(metal ion binding)|go:"GO:0048468"(cell development)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0072593"(reactive oxygen species metabolic process) ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 - comment:mint|function:"NADH-cytochrome b5 reductase involved in endolasmic reticulum stress response pathway. Plays a critical role in protecting pancreatic beta-cells against oxidant stress, possibly by protecting the cell from excess buildup of reactive oxygen species (ROS)" - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/24 rogid:j19wK584v3ZVxPwALGRiJ1DnnvU10090 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rigid:YHELBtRCNJ306pLhTYkfsHzucVM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P97868 uniprotkb:Q83A33 intact:EBI-8329311|uniprotkb:P70287|uniprotkb:Q8R399|uniprotkb:Q3TTR9|uniprotkb:Q4U217|uniprotkb:Q3UMP7|intact:MINT-4106375|uniprotkb:Q3TUM7|uniprotkb:Q7TT06|uniprotkb:Q8BNY8|ensembl:ENSMUSP00000049528 intact:EBI-21286457|ensemblbacteria:AAO91562 psi-mi:rbbp6_mouse(display_long)|uniprotkb:Rbbp6(gene name)|psi-mi:Rbbp6(display_short)|uniprotkb:P2pr(gene name synonym)|uniprotkb:Pact(gene name synonym)|uniprotkb:p53-associated cellular protein of testis(gene name synonym)|uniprotkb:Proliferation potential-related protein(gene name synonym)|uniprotkb:Protein P2P-R(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 6(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RBBP6(gene name synonym) psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288627|imex:IM-26899-217 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035377.2|refseq:NP_778188.1|refseq:XP_006507533.1|ensembl:ENSMUSG00000030779(gene)|ensembl:ENSMUST00000052135(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006260"(DNA replication)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006397"(mRNA processing)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0048568"(embryonic organ development)|go:"GO:0061053"(somite development)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR003613(U box)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014891(DWNN domain)|interpro:IPR025829|interpro:IPR033489|interpro:IPR036875|mint:P97868|reactome:R-MMU-9013422|reactome:R-MMU-983168 ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 - comment:mint - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/24 rogid:mpPVAoOa4h9lRTIZhKfpI5Po5cg10090 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rigid:F6BN/LvEdPkVkFZaR70fbDqQzbE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BY87 uniprotkb:Q83A33 intact:EBI-8420047|intact:MINT-4110662|uniprotkb:Q80V06|uniprotkb:Q8BUW4|uniprotkb:Q91X25|uniprotkb:Q6KAR9|uniprotkb:Q8BI16|uniprotkb:Q32NY0|uniprotkb:Q5EBP2|uniprotkb:Q8BI15|uniprotkb:Q8BHU1|ensembl:ENSMUSP00000147619 intact:EBI-21286457|ensemblbacteria:AAO91562 psi-mi:ubp47_mouse(display_long)|uniprotkb:Usp47(gene name)|psi-mi:Usp47(display_short)|uniprotkb:Ubiquitin thioesterase 47(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 47(gene name synonym)|uniprotkb:Deubiquitinating enzyme 47(gene name synonym) psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288635|imex:IM-26899-639 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_598519.2|refseq:NP_796223.2|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR029071|interpro:IPR038765|mint:Q8BY87|reactome:R-MMU-5689880|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|ensembl:ENSMUSG00000059263(gene)|ensembl:ENSMUST00000210309(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006284"(base-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034644"(cellular response to UV) ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 - comment:mint - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/24 rogid:+7NgU4JY6ZGpOCRW+1vJE0sS6os10090 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rigid:HbfdVGYHOuDgkHhCTVSs44kIbMM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z0J0 uniprotkb:Q83B01 intact:EBI-8408018|intact:MINT-4104065|uniprotkb:Q3UB23|ensembl:ENSMUSP00000021668 intact:EBI-21286307|ensemblbacteria:AAO91219 psi-mi:npc2_mouse(display_long)|uniprotkb:Npc2(gene name)|psi-mi:Npc2(display_short)|uniprotkb:Niemann Pick type C2 protein homolog(gene name synonym)|uniprotkb:Epididymal secretory protein E1(gene name synonym) psi-mi:q83b01_coxbu(display_long)|uniprotkb:CBU_1724(locus name) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288591|imex:IM-26899-459 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_075898.1|ensembl:ENSMUSG00000021242(gene)|ensembl:ENSMUST00000021668(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015918"(sterol transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0030301"(cholesterol transport)|go:"GO:0032366"(intracellular sterol transport)|go:"GO:0032367"(intracellular cholesterol transport)|go:"GO:0032934"(sterol binding)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR003172(MD-2-related lipid-recognition)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR033916|interpro:IPR039670|mint:Q9Z0J0|reactome:R-MMU-6798695|reactome:R-MMU-8964038 ensemblbacteria:AAO91219(transcript)|ensemblbacteria:CBU_1724(gene)|refseq:NP_820705.1|refseq:WP_010958395.1|interpro:IPR036770|mint:Q83B01 - comment:mint|function:May be involved in the regulation of the lipid composition of sperm membranes during the maturation in the epididymis - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/24 rogid:eDUNxC5PVN2I/spwfEGtuIV7dOI10090 rogid:JJEGYYiXBmLJc7c184Y3xpftK98227377 rigid:kYsuhoPPp5GlfpQX7ThLW8s9Jv0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z0J0 uniprotkb:Q83A33 intact:EBI-8408018|intact:MINT-4104065|uniprotkb:Q3UB23|ensembl:ENSMUSP00000021668 intact:EBI-21286457|ensemblbacteria:AAO91562 psi-mi:npc2_mouse(display_long)|uniprotkb:Npc2(gene name)|psi-mi:Npc2(display_short)|uniprotkb:Niemann Pick type C2 protein homolog(gene name synonym)|uniprotkb:Epididymal secretory protein E1(gene name synonym) psi-mi:q83a33_coxbu(display_long)|uniprotkb:CBU_2078(locus name) psi-mi:"MI:0397"(two hybrid array) Wallqvist et al. (2016) imex:IM-26899|doi:10.1371/journal.pone.0188071|pubmed:29176882 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:227377(coxbu)|taxid:227377("Coxiella burnetii (strain RSA 493 / Nine Mile phase I)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-21288619|imex:IM-26899-845 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_075898.1|ensembl:ENSMUSG00000021242(gene)|ensembl:ENSMUST00000021668(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015918"(sterol transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0030301"(cholesterol transport)|go:"GO:0032366"(intracellular sterol transport)|go:"GO:0032367"(intracellular cholesterol transport)|go:"GO:0032934"(sterol binding)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR003172(MD-2-related lipid-recognition)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR033916|interpro:IPR039670|mint:Q9Z0J0|reactome:R-MMU-6798695|reactome:R-MMU-8964038 ensemblbacteria:AAO91562(transcript)|ensemblbacteria:CBU_2078(gene)|refseq:NP_821048.1|refseq:WP_005769896.1|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597|interpro:IPR040198|mint:Q83A33 - comment:mint|function:May be involved in the regulation of the lipid composition of sperm membranes during the maturation in the epididymis - figure legend:ST2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/06 2019/04/24 rogid:eDUNxC5PVN2I/spwfEGtuIV7dOI10090 rogid:7ydFr8QWmCdJly44hK7iRqNh5Lw227377 rigid:Are5FaFIUKrLg7rGA3cAJ7KVOmY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)