#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O01767	uniprotkb:Q20402	intact:EBI-2476926|ensemblmetazoa:T21E3.1.1	intact:EBI-2476895|ensemblmetazoa:F44F4.2.1|ensemblmetazoa:F44F4.2.2	psi-mi:egg4_caeel(display_long)|uniprotkb:egg-4(gene name)|psi-mi:egg-4(display_short)|uniprotkb:Egg sterile protein 4(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase-like protein egg-4(gene name synonym)|uniprotkb:T21E3.1(orf name)	psi-mi:egg3_caeel(display_long)|uniprotkb:egg-3(gene name)|psi-mi:egg-3(display_short)|uniprotkb:Egg sterile protein 3(gene name synonym)|uniprotkb:F44F4.2(orf name)	psi-mi:"MI:0018"(two hybrid)	Parry et al. (2009)	pubmed:19879147|imex:IM-26355	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16877428|imex:IM-26355-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:T21E3.1.1(transcript)|ensemblmetazoa:WBGene00020652(gene)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030703"(eggshell formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|refseq:NP_491269.1|wormbase:T21E3.1|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR029021	go:"GO:0030703"(eggshell formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|ensemblmetazoa:F44F4.2.1(transcript)|ensemblmetazoa:F44F4.2.2(transcript)|ensemblmetazoa:WBGene00009701(gene)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005938"(cell cortex)|go:"GO:0019901"(protein kinase binding)|interpro:IPR029021|refseq:NP_496341.1|wormbase:F44F4.2|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)	-	-	-	figure legend:Fig. 4G|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2018/03/12	2018/03/12	rogid:Zpy5XrJwZG0rJEAvwRq0EDJZha06239	rogid:LZSWtgn56eXltr+itq6Y8ABnCgU6239	rigid:OW8QMJJ+FCN7pdR8sPLx6w20sqc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O01767	uniprotkb:Q9XTF3	intact:EBI-2476926|ensemblmetazoa:T21E3.1.1	intact:EBI-2005616|uniprotkb:H9G2V8|uniprotkb:H9G2V9|uniprotkb:J7SF89|uniprotkb:Q27GP3|uniprotkb:Q2EEP1|uniprotkb:Q9TVF4|uniprotkb:Q20604|intact:EBI-2476794|ensemblmetazoa:F49E11.1b.1	psi-mi:egg4_caeel(display_long)|uniprotkb:egg-4(gene name)|psi-mi:egg-4(display_short)|uniprotkb:Egg sterile protein 4(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase-like protein egg-4(gene name synonym)|uniprotkb:T21E3.1(orf name)	psi-mi:mbk2_caeel(display_long)|uniprotkb:mbk-2(gene name)|psi-mi:mbk-2(display_short)|uniprotkb:F49E11.1(orf name)|uniprotkb:Minibrain Kinase 2(gene name synonym)|uniprotkb:Dual specificity Yak1-related kinase mbk-2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Parry et al. (2009)	pubmed:19879147|imex:IM-26355	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16877432|imex:IM-26355-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:T21E3.1.1(transcript)|ensemblmetazoa:WBGene00020652(gene)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030703"(eggshell formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|refseq:NP_491269.1|wormbase:T21E3.1|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR029021	refseq:NP_001023207.1|refseq:NP_001023208.1|refseq:NP_001040950.1|refseq:NP_001040951.1|refseq:NP_502492.2|wormbase:F49E11.1a|wormbase:F49E11.1b|wormbase:F49E11.1c|wormbase:F49E11.1d|wormbase:F49E11.1e|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|wormbase:F49E11.1f|wormbase:F49E11.1g|wormbase:F49E11.1h|refseq:NP_001255694.1|refseq:NP_001255695.1|refseq:NP_001263802.1|interpro:IPR042521|ensemblmetazoa:F49E11.1b.1(transcript)|ensemblmetazoa:WBGene00003150(gene)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000793"(condensed chromosome)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043186"(P granule)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903864"(P granule disassembly)	-	-	-	figure legend:Fig. 4G|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2018/03/12	2018/03/12	rogid:Zpy5XrJwZG0rJEAvwRq0EDJZha06239	rogid:e0FXCawkUfjiG3D8gHgm4cJMoOU6239	rigid:YMa0ECD5Jw3wtxqd2BwXPIfjRX4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q20402	uniprotkb:Q9XTF3	intact:EBI-2476895|ensemblmetazoa:F44F4.2.1|ensemblmetazoa:F44F4.2.2	intact:EBI-2005616|uniprotkb:H9G2V8|uniprotkb:H9G2V9|uniprotkb:J7SF89|uniprotkb:Q27GP3|uniprotkb:Q2EEP1|uniprotkb:Q9TVF4|uniprotkb:Q20604|intact:EBI-2476794|ensemblmetazoa:F49E11.1b.1	psi-mi:egg3_caeel(display_long)|uniprotkb:egg-3(gene name)|psi-mi:egg-3(display_short)|uniprotkb:Egg sterile protein 3(gene name synonym)|uniprotkb:F44F4.2(orf name)	psi-mi:mbk2_caeel(display_long)|uniprotkb:mbk-2(gene name)|psi-mi:mbk-2(display_short)|uniprotkb:F49E11.1(orf name)|uniprotkb:Minibrain Kinase 2(gene name synonym)|uniprotkb:Dual specificity Yak1-related kinase mbk-2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Parry et al. (2009)	pubmed:19879147|imex:IM-26355	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16877436|imex:IM-26355-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0030703"(eggshell formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|ensemblmetazoa:F44F4.2.1(transcript)|ensemblmetazoa:F44F4.2.2(transcript)|ensemblmetazoa:WBGene00009701(gene)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005938"(cell cortex)|go:"GO:0019901"(protein kinase binding)|interpro:IPR029021|refseq:NP_496341.1|wormbase:F44F4.2|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)	refseq:NP_001023207.1|refseq:NP_001023208.1|refseq:NP_001040950.1|refseq:NP_001040951.1|refseq:NP_502492.2|wormbase:F49E11.1a|wormbase:F49E11.1b|wormbase:F49E11.1c|wormbase:F49E11.1d|wormbase:F49E11.1e|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|wormbase:F49E11.1f|wormbase:F49E11.1g|wormbase:F49E11.1h|refseq:NP_001255694.1|refseq:NP_001255695.1|refseq:NP_001263802.1|interpro:IPR042521|ensemblmetazoa:F49E11.1b.1(transcript)|ensemblmetazoa:WBGene00003150(gene)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000793"(condensed chromosome)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043186"(P granule)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903864"(P granule disassembly)	-	-	-	figure legend:Fig. 4G|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2018/03/12	2018/03/12	rogid:LZSWtgn56eXltr+itq6Y8ABnCgU6239	rogid:e0FXCawkUfjiG3D8gHgm4cJMoOU6239	rigid:5ileSvtKNlgD5E94XxhddugbCmk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q94148	uniprotkb:Q8MYQ0	intact:EBI-16877441|ensemblmetazoa:T23H2.5.1|ensemblmetazoa:T23H2.5.2|uniprotkb:I7FXD6	intact:EBI-330263|ensemblmetazoa:F36D4.3c.1|ensemblmetazoa:F36D4.3c.2	psi-mi:rab10_caeel(display_long)|uniprotkb:rab-10(gene name)|psi-mi:rab-10(display_short)|uniprotkb:T23H2.5(orf name)	psi-mi:q8myq0_caeel(display_long)|uniprotkb:hum-2(gene name)|psi-mi:hum-2(display_short)|uniprotkb:F36D4.3(orf name)|uniprotkb:CELE_F36D4.3(orf name)	psi-mi:"MI:0018"(two hybrid)	Parry et al. (2009)	pubmed:19879147|imex:IM-26355	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16877479|imex:IM-26355-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-CEL-8873719|ensemblmetazoa:T23H2.5.1(transcript)|ensemblmetazoa:T23H2.5.2(transcript)|ensemblmetazoa:WBGene00004273(gene)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001881"(receptor recycling)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0005886"(plasma membrane)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030424"(axon)|go:"GO:0031045"(dense core granule)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043025"(neuronal cell body)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1902647"(negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process)|go:"GO:1904951"(positive regulation of establishment of protein localization)|refseq:NP_491857.1|wormbase:T23H2.5|reactome:R-CEL-6798695|reactome:R-CEL-8876198|interpro:IPR027417|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)	interpro:IPR002710(Dilute)|refseq:NP_741590.1|wormbase:F36D4.3c|ensemblmetazoa:F36D4.3c.1(transcript)|ensemblmetazoa:F36D4.3c.2(transcript)|ensemblmetazoa:WBGene00002036(gene)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0031982"(vesicle)|go:"GO:0051015"(actin filament binding)	-	-	-	figure legend:Fig. 4G|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2018/03/12	2018/03/12	rogid:BjhIqOtkoRQYCoOkMmhp5IR8Y5k6239	rogid:AN+VSfUA5w+MoSL0+Z3yUZ5Iwwk6239	rigid:4CUws55UgnHavzXaMMw+2E4CMyE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)