#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q16236	uniprotkb:O95718-3	intact:EBI-2007911|uniprotkb:Q53RW6|uniprotkb:Q59HH2|uniprotkb:Q96F71|uniprotkb:B2RBU2|uniprotkb:B4E338|uniprotkb:E9PGJ7|intact:EBI-28978278|ensembl:ENSP00000380252	intact:EBI-20585243	psi-mi:nf2l2_human(display_long)|uniprotkb:NFE2L2(gene name)|psi-mi:NFE2L2(display_short)|uniprotkb:NRF2(gene name synonym)|uniprotkb:Nuclear factor, erythroid derived 2, like 2(gene name synonym)|uniprotkb:HEBP1(gene name synonym)	psi-mi:o95718-3(display_long)|uniprotkb:ESRRB(gene name)|psi-mi:ESRRB(display_short)|uniprotkb:ERR beta-2(gene name synonym)|uniprotkb:Estrogen receptor-like 2(gene name synonym)|uniprotkb:Estrogen-related receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group B member 2(gene name synonym)|uniprotkb:ERRbeta-short-form(isoform synonym)|uniprotkb:ERRB2(gene name synonym)|uniprotkb:ESRL2(gene name synonym)|uniprotkb:NR3B2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Zhou et al. (2007)	pubmed:17920186|imex:IM-26438	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20585241|imex:IM-26438-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000380252|ensembl:ENST00000397063|ensembl:ENSP00000380253|ensembl:ENST00000446151|ensembl:ENSP00000411575|ensembl:ENST00000464747|ensembl:ENSP00000467401|refseq:NP_001300829.1|refseq:NP_001300830.1|refseq:NP_001138884.1|refseq:NP_006155.2|refseq:NP_001138885.1|dip:DIP-29971N|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|go:"GO:2000121"(regulation of removal of superoxide radicals)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029845|mint:Q16236|rcsb pdb:2FLU|rcsb pdb:2LZ1|rcsb pdb:3ZGC|rcsb pdb:4IFL|rcsb pdb:5WFV|rcsb pdb:6T7V|reactome:R-HSA-8932339|reactome:R-HSA-9707587|reactome:R-HSA-9707616|ensembl:ENSG00000116044(gene)|ensembl:ENST00000397062(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007568"(aging)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035690"|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046223"(aflatoxin catabolic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|go:"GO:1903788"(positive regulation of glutathione biosynthetic process)	intact:EBI-1042744(isoform-parent)	-	-	-	figure legend:Figure 7,9|comment:At least two sites, one likely located within the D domain and one within the A/B-C domains of SFhERR-beta are capable of interacting with Nrf2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2018/05/08	2018/06/05	rogid:EjSeL1dJClhC2vIPip6QDc8QAUk9606	rogid:UtZYFAwSICzVqImLfk8DS2JwtDY9606	rigid:ShtMc0U/lPwyg8371f+9EaAQe60	false	ha tag:?-?	myc tag:n-n|sufficient binding region:1-169|necessary binding region:169-210	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q16236	uniprotkb:O95718-3	intact:EBI-2007911|uniprotkb:Q53RW6|uniprotkb:Q59HH2|uniprotkb:Q96F71|uniprotkb:B2RBU2|uniprotkb:B4E338|uniprotkb:E9PGJ7|intact:EBI-28978278|ensembl:ENSP00000380252	intact:EBI-20585243	psi-mi:nf2l2_human(display_long)|uniprotkb:NFE2L2(gene name)|psi-mi:NFE2L2(display_short)|uniprotkb:NRF2(gene name synonym)|uniprotkb:Nuclear factor, erythroid derived 2, like 2(gene name synonym)|uniprotkb:HEBP1(gene name synonym)	psi-mi:o95718-3(display_long)|uniprotkb:ESRRB(gene name)|psi-mi:ESRRB(display_short)|uniprotkb:ERR beta-2(gene name synonym)|uniprotkb:Estrogen receptor-like 2(gene name synonym)|uniprotkb:Estrogen-related receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group B member 2(gene name synonym)|uniprotkb:ERRbeta-short-form(isoform synonym)|uniprotkb:ERRB2(gene name synonym)|uniprotkb:ESRL2(gene name synonym)|uniprotkb:NR3B2(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Zhou et al. (2007)	pubmed:17920186|imex:IM-26438	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20585267|imex:IM-26438-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000380252|ensembl:ENST00000397063|ensembl:ENSP00000380253|ensembl:ENST00000446151|ensembl:ENSP00000411575|ensembl:ENST00000464747|ensembl:ENSP00000467401|refseq:NP_001300829.1|refseq:NP_001300830.1|refseq:NP_001138884.1|refseq:NP_006155.2|refseq:NP_001138885.1|dip:DIP-29971N|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|go:"GO:2000121"(regulation of removal of superoxide radicals)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029845|mint:Q16236|rcsb pdb:2FLU|rcsb pdb:2LZ1|rcsb pdb:3ZGC|rcsb pdb:4IFL|rcsb pdb:5WFV|rcsb pdb:6T7V|reactome:R-HSA-8932339|reactome:R-HSA-9707587|reactome:R-HSA-9707616|ensembl:ENSG00000116044(gene)|ensembl:ENST00000397062(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007568"(aging)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035690"|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046223"(aflatoxin catabolic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|go:"GO:1903788"(positive regulation of glutathione biosynthetic process)	intact:EBI-1042744(isoform-parent)	-	-	-	figure legend:Figure 6B|comment:77.7% of the HA-Nrf2 positively stained cells showed that HA-Nrf2 translocated into the nucleus and co-localized with SFhERR-beta.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2018/05/08	2018/06/05	rogid:EjSeL1dJClhC2vIPip6QDc8QAUk9606	rogid:UtZYFAwSICzVqImLfk8DS2JwtDY9606	rigid:ShtMc0U/lPwyg8371f+9EaAQe60	false	ha tag:?-?	myc tag:n-n	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)