#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q15116 uniprotkb:Q9NZQ7-1 intact:EBI-4314328|uniprotkb:O00517|uniprotkb:Q8IX89|intact:EBI-28971758|ensembl:ENSP00000335062|ensembl:ENSP00000480684 intact:EBI-15686469|ensembl:ENSP00000370989 psi-mi:pdcd1_human(display_long)|uniprotkb:PDCD1(gene name)|psi-mi:PDCD1(display_short)|uniprotkb:PD1(gene name synonym) psi-mi:q9nzq7-1(display_long)|uniprotkb:CD274(gene name)|psi-mi:CD274(display_short)|uniprotkb:B7H1(gene name synonym)|uniprotkb:PDCD1L1(gene name synonym)|uniprotkb:PDCD1LG1(gene name synonym)|uniprotkb:PDL1(gene name synonym)|uniprotkb:PD-L1I(isoform synonym)|uniprotkb:B7 homolog 1(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Zak et al. (2015) pubmed:26602187|doi:10.1016/j.str.2015.09.010|imex:IM-25131 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16185806|imex:IM-25131-1|dip:DIP-200470E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005009.2|ensembl:ENSP00000335062|ensembl:ENSP00000480684|ensembl:ENSG00000188389(gene)|ensembl:ENSG00000276977(gene)|ensembl:ENST00000334409(transcript)|ensembl:ENST00000618185(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006959"(humoral immune response)|go:"GO:0007275"(multicellular organism development)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050777"(negative regulation of immune response)|go:"GO:0070234"(positive regulation of T cell apoptotic process)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR042379|mint:Q15116|rcsb pdb:2M2D|rcsb pdb:3RRQ|rcsb pdb:4ZQK|rcsb pdb:5B8C|rcsb pdb:5GGR|rcsb pdb:5GGS|rcsb pdb:5IUS|rcsb pdb:5JXE|rcsb pdb:5WT9|rcsb pdb:6HIG|rcsb pdb:6J14|rcsb pdb:6J15|rcsb pdb:6JBT|rcsb pdb:6JJP|rcsb pdb:6K0Y|rcsb pdb:6R5G|rcsb pdb:6ROY|rcsb pdb:6ROZ|rcsb pdb:6UMT|rcsb pdb:6UMU|rcsb pdb:6UMV|rcsb pdb:6XKR|rcsb pdb:7BXA|rcsb pdb:7CGW|rcsb pdb:7CU5|reactome:R-HSA-389948|reactome:R-HSA-9679191|dip:DIP-44126N intact:EBI-4314282(isoform-parent)|ensembl:ENSG00000120217(gene)|ensembl:ENST00000381577(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:/2q/ETcmMQyfvNb1CvRfrVc9f4s9606 rogid:xgS8qLw0RrD1mMV3JswLYfX8NBQ9606 rigid:UCghd0MiNpAZwi8Qa4DDpPh4u+o false sufficient binding region:33-150 sufficient binding region:18-134 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15116 uniprotkb:Q9NZQ7-1 intact:EBI-4314328|uniprotkb:O00517|uniprotkb:Q8IX89|intact:EBI-28971758|ensembl:ENSP00000335062|ensembl:ENSP00000480684 intact:EBI-15686469|ensembl:ENSP00000370989 psi-mi:pdcd1_human(display_long)|uniprotkb:PDCD1(gene name)|psi-mi:PDCD1(display_short)|uniprotkb:PD1(gene name synonym) psi-mi:q9nzq7-1(display_long)|uniprotkb:CD274(gene name)|psi-mi:CD274(display_short)|uniprotkb:B7H1(gene name synonym)|uniprotkb:PDCD1L1(gene name synonym)|uniprotkb:PDCD1LG1(gene name synonym)|uniprotkb:PDL1(gene name synonym)|uniprotkb:PD-L1I(isoform synonym)|uniprotkb:B7 homolog 1(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Zak et al. (2015) pubmed:26602187|doi:10.1016/j.str.2015.09.010|imex:IM-25131 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16185828|imex:IM-25131-2|dip:DIP-200470E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005009.2|ensembl:ENSP00000335062|ensembl:ENSP00000480684|ensembl:ENSG00000188389(gene)|ensembl:ENSG00000276977(gene)|ensembl:ENST00000334409(transcript)|ensembl:ENST00000618185(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006959"(humoral immune response)|go:"GO:0007275"(multicellular organism development)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050777"(negative regulation of immune response)|go:"GO:0070234"(positive regulation of T cell apoptotic process)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR042379|mint:Q15116|rcsb pdb:2M2D|rcsb pdb:3RRQ|rcsb pdb:4ZQK|rcsb pdb:5B8C|rcsb pdb:5GGR|rcsb pdb:5GGS|rcsb pdb:5IUS|rcsb pdb:5JXE|rcsb pdb:5WT9|rcsb pdb:6HIG|rcsb pdb:6J14|rcsb pdb:6J15|rcsb pdb:6JBT|rcsb pdb:6JJP|rcsb pdb:6K0Y|rcsb pdb:6R5G|rcsb pdb:6ROY|rcsb pdb:6ROZ|rcsb pdb:6UMT|rcsb pdb:6UMU|rcsb pdb:6UMV|rcsb pdb:6XKR|rcsb pdb:7BXA|rcsb pdb:7CGW|rcsb pdb:7CU5|reactome:R-HSA-389948|reactome:R-HSA-9679191|dip:DIP-44126N intact:EBI-4314282(isoform-parent)|ensembl:ENSG00000120217(gene)|ensembl:ENST00000381577(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:/2q/ETcmMQyfvNb1CvRfrVc9f4s9606 rogid:xgS8qLw0RrD1mMV3JswLYfX8NBQ9606 rigid:UCghd0MiNpAZwi8Qa4DDpPh4u+o false sufficient binding region:33-150 sufficient binding region:18-134 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)