#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q32MD9 uniprotkb:Q8C3Q9 intact:EBI-7017034|ensembl:ENSMUSP00000045547|ensembl:ENSMUSP00000113977|uniprotkb:E9QKV9|intact:UNK-5400048|uniprotkb:O88971 intact:EBI-16069049|ensembl:ENSMUSP00000030747 psi-mi:cdon_mouse(display_long)|uniprotkb:Cdon(gene name)|psi-mi:Cdon(display_short)|uniprotkb:Cdo(gene name synonym) psi-mi:casp9_mouse(display_long)|uniprotkb:Casp9(gene name)|psi-mi:Casp9(display_short)|uniprotkb:Mch6(gene name synonym)|uniprotkb:Apoptotic protease Mch-6(gene name synonym)|uniprotkb:Apoptotic protease-activating factor 3(gene name synonym)|uniprotkb:ICE-like apoptotic protease 6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Delloye-Bourgeois et al. (2012) pubmed:23940460|doi:10.1371/journal.pbio.1001623|imex:IM-21564 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16069103|imex:IM-21564-1|dip:DIP-191962E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006510570.1|refseq:XP_006510571.1|refseq:XP_006510572.1|refseq:XP_006510573.1|refseq:XP_006510574.1|refseq:XP_011240883.1|dip:DIP-57227N|ensembl:ENSMUSG00000038119(gene)|ensembl:ENSMUST00000042842(transcript)|ensembl:ENSMUST00000119129(transcript)|go:"GO:0001708"(cell fate specification)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007520"(myoblast fusion)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009986"(cell surface)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0014816"(skeletal muscle satellite cell differentiation)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0051057"(positive regulation of small GTPase mediated signal transduction)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0060059"(embryonic retina morphogenesis in camera-type eye)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032983|interpro:IPR036116|interpro:IPR036179|mint:Q32MD9|reactome:R-MMU-525793|reactome:R-MMU-5632681|reactome:R-MMU-5635838|go:"GO:0043393"(regulation of protein binding)|refseq:NP_067314.2 ensembl:ENSMUSG00000028914(gene)|ensembl:ENSMUST00000030747(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002931"(response to ischemia)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007568"(aging)|go:"GO:0008233"(peptidase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009411"(response to UV)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032025"(response to cobalt ion)|go:"GO:0032355"(response to estradiol)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034349"(glial cell apoptotic process)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043293"(apoptosome)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0046677"(response to antibiotic)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071887"(leukocyte apoptotic process)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0097199"(cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR011029(DEATH-like)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|interpro:IPR033171|interpro:IPR042147|reactome:R-MMU-111458|reactome:R-MMU-111459|reactome:R-MMU-168638|reactome:R-MMU-198323|reactome:R-MMU-418889|reactome:R-MMU-9627069|go:"GO:2001020"(regulation of response to DNA damage stimulus)|refseq:NP_056548.2|dip:DIP-60482N psi-mi:"MI:0465"(dip) comment:mint|function:Component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells. Promotes differentiation of myogenic cells. Required for response to NTN3 and activation of NFATC3 - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/07 2018/09/27 rogid:GYx35GRWYwplerMIaopmyqHx6Jw10090 rogid:Yvb0dZyTZJjBVKVo8tcCuPh5+2Q10090 rigid:AC6tXLNZLWdu+kw2EbIeDFhq6s4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q32MD9 uniprotkb:P55211 intact:EBI-7017034|ensembl:ENSMUSP00000045547|ensembl:ENSMUSP00000113977|uniprotkb:E9QKV9|intact:UNK-5400048|uniprotkb:O88971 intact:EBI-516799|uniprotkb:O95348|uniprotkb:Q92852|uniprotkb:Q9BQ62|uniprotkb:Q9UEQ3|uniprotkb:Q9UIJ8|uniprotkb:Q53Y70|uniprotkb:Q5JRU9|uniprotkb:Q5UGI1|uniprotkb:B4E1A3|ensembl:ENSP00000330237 psi-mi:cdon_mouse(display_long)|uniprotkb:Cdon(gene name)|psi-mi:Cdon(display_short)|uniprotkb:Cdo(gene name synonym) psi-mi:casp9_human(display_long)|uniprotkb:ICE-like apoptotic protease 6(gene name synonym)|uniprotkb:Apoptotic protease Mch-6(gene name synonym)|uniprotkb:Apoptotic protease-activating factor 3(gene name synonym)|uniprotkb:CASP9(gene name)|psi-mi:CASP9(display_short)|uniprotkb:MCH6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Delloye-Bourgeois et al. (2012) pubmed:23940460|doi:10.1371/journal.pbio.1001623|imex:IM-21564 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16069120|imex:IM-21564-2|dip:DIP-191964E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006510570.1|refseq:XP_006510571.1|refseq:XP_006510572.1|refseq:XP_006510573.1|refseq:XP_006510574.1|refseq:XP_011240883.1|dip:DIP-57227N|ensembl:ENSMUSG00000038119(gene)|ensembl:ENSMUST00000042842(transcript)|ensembl:ENSMUST00000119129(transcript)|go:"GO:0001708"(cell fate specification)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007520"(myoblast fusion)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009986"(cell surface)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0014816"(skeletal muscle satellite cell differentiation)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0051057"(positive regulation of small GTPase mediated signal transduction)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0060059"(embryonic retina morphogenesis in camera-type eye)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032983|interpro:IPR036116|interpro:IPR036179|mint:Q32MD9|reactome:R-MMU-525793|reactome:R-MMU-5632681|reactome:R-MMU-5635838|go:"GO:0043393"(regulation of protein binding)|refseq:NP_067314.2 refseq:NP_001264983.1|refseq:NP_001220.2|refseq:NP_127463.2|refseq:XP_005246071.1|dip:DIP-27625N|ensembl:ENSG00000132906(gene)|ensembl:ENST00000333868(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002931"(response to ischemia)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007568"(aging)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008233"(peptidase activity)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008635"(activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030220"(platelet formation)|go:"GO:0032025"(response to cobalt ion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034349"(glial cell apoptotic process)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043293"(apoptosome)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0046677"(response to antibiotic)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071887"(leukocyte apoptotic process)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0097199"(cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR011029(DEATH-like)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|interpro:IPR033171|interpro:IPR042147|mint:P55211|rcsb pdb:1JXQ|rcsb pdb:1NW9|rcsb pdb:2AR9|rcsb pdb:3D9T|rcsb pdb:3V3K|rcsb pdb:3YGS|rcsb pdb:4RHW|rcsb pdb:5JUY|rcsb pdb:5WVC|rcsb pdb:5WVE|reactome:R-HSA-111458|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-168638|reactome:R-HSA-198323|reactome:R-HSA-418889|reactome:R-HSA-5674400|reactome:R-HSA-9627069 psi-mi:"MI:0465"(dip) comment:mint|function:Component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells. Promotes differentiation of myogenic cells. Required for response to NTN3 and activation of NFATC3 - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:GYx35GRWYwplerMIaopmyqHx6Jw10090 rogid:IYW59Vh17AEnXa6/wLpkIPNE0Bo9606 rigid:oMfIrm7i+i6DuJi/KmmsPIyA/LU false - flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q32MD9 uniprotkb:P42574 intact:EBI-7017034|ensembl:ENSMUSP00000045547|ensembl:ENSMUSP00000113977|uniprotkb:E9QKV9|intact:UNK-5400048|uniprotkb:O88971 intact:EBI-524064|ensembl:ENSP00000311032|ensembl:ENSP00000428929|uniprotkb:Q96AN1|uniprotkb:Q96KP2|uniprotkb:A8K5M2|uniprotkb:D3DP53 psi-mi:cdon_mouse(display_long)|uniprotkb:Cdon(gene name)|psi-mi:Cdon(display_short)|uniprotkb:Cdo(gene name synonym) psi-mi:casp3_human(display_long)|uniprotkb:Apopain(gene name synonym)|uniprotkb:Cysteine protease CPP32(gene name synonym)|uniprotkb:Protein Yama(gene name synonym)|uniprotkb:SREBP cleavage activity 1(gene name synonym)|uniprotkb:CASP3(gene name)|psi-mi:CASP3(display_short)|uniprotkb:CPP32(gene name synonym) psi-mi:"MI:0435"(protease assay) Delloye-Bourgeois et al. (2012) pubmed:23940460|doi:10.1371/journal.pbio.1001623|imex:IM-21564 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0570"(protein cleavage) psi-mi:"MI:0465"(DIP) intact:EBI-16069139|imex:IM-21564-3|dip:DIP-191963E - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006510570.1|refseq:XP_006510571.1|refseq:XP_006510572.1|refseq:XP_006510573.1|refseq:XP_006510574.1|refseq:XP_011240883.1|dip:DIP-57227N|ensembl:ENSMUSG00000038119(gene)|ensembl:ENSMUST00000042842(transcript)|ensembl:ENSMUST00000119129(transcript)|go:"GO:0001708"(cell fate specification)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007520"(myoblast fusion)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009986"(cell surface)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0014816"(skeletal muscle satellite cell differentiation)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0051057"(positive regulation of small GTPase mediated signal transduction)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0060059"(embryonic retina morphogenesis in camera-type eye)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032983|interpro:IPR036116|interpro:IPR036179|mint:Q32MD9|reactome:R-MMU-525793|reactome:R-MMU-5632681|reactome:R-MMU-5635838|go:"GO:0043393"(regulation of protein binding)|refseq:NP_067314.2 go:"GO:0009749"(response to glucose)|go:"GO:0001554"(luteolysis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002020"(protease binding)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005123"(death receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000164305(gene)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|ensembl:ENST00000308394(transcript)|ensembl:ENST00000523916(transcript)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007611"(learning or memory)|go:"GO:0008233"(peptidase activity)|go:"GO:0008627"(intrinsic apoptotic signaling pathway in response to osmotic stress)|go:"GO:0009411"(response to UV)|go:"GO:0010165"(response to X-ray)|go:"GO:0016005"(phospholipase A2 activator activity)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016485"(protein processing)|go:"GO:0021766"(hippocampus development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031264"(death-inducing signaling complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032025"(response to cobalt ion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034349"(glial cell apoptotic process)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035094"(response to nicotine)|go:"GO:0042060"(wound healing)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043200"(response to amino acid)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045165"(cell fate commitment)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0061713"(anterior neural tube closure)|go:"GO:0071887"(leukocyte apoptotic process)|go:"GO:0072734"(cellular response to staurosporine)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0097199"(cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|rcsb pdb:1GFW|rcsb pdb:1I3O|rcsb pdb:1NME|rcsb pdb:1NMQ|rcsb pdb:1NMS|interpro:IPR015471(Caspase-7)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|mint:P42574|interpro:IPR002398(Peptidase C14, caspase precursor p45)|rcsb pdb:1CP3|rcsb pdb:4QUH|rcsb pdb:4QUI|rcsb pdb:4QUD|rcsb pdb:4QUJ|rcsb pdb:4QUL|rcsb pdb:5I9B|rcsb pdb:5I9T|rcsb pdb:5IAB|rcsb pdb:5IAE|rcsb pdb:5IAG|rcsb pdb:4QUE|rcsb pdb:5IAJ|rcsb pdb:4QUG|rcsb pdb:5IAK|rcsb pdb:5IAN|rcsb pdb:5IAR|rcsb pdb:5IAS|rcsb pdb:5IBC|rcsb pdb:5IBP|rcsb pdb:5IBR|rcsb pdb:5IC4|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111465|reactome:R-HSA-111469|reactome:R-HSA-140342|reactome:R-HSA-1474228|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-211736|reactome:R-HSA-264870|reactome:R-HSA-351906|reactome:R-HSA-418889|reactome:R-HSA-449836|reactome:R-HSA-5620971|reactome:R-HSA-111464|rcsb pdb:1QX3|rcsb pdb:1RE1|rcsb pdb:1RHJ|rcsb pdb:1RHK|rcsb pdb:1RHM|rcsb pdb:1RHQ|rcsb pdb:1RHR|rcsb pdb:1RHU|rcsb pdb:2C1E|rcsb pdb:2C2K|rcsb pdb:2C2M|rcsb pdb:2C2O|rcsb pdb:2CDR|rcsb pdb:2CJX|rcsb pdb:2CJY|rcsb pdb:2CNK|rcsb pdb:2CNL|rcsb pdb:2CNN|rcsb pdb:2CNO|rcsb pdb:2DKO|rcsb pdb:2H5I|rcsb pdb:2H5J|rcsb pdb:2H65|rcsb pdb:2J30|rcsb pdb:2J31|rcsb pdb:2J32|rcsb pdb:2J33|rcsb pdb:2XYG|rcsb pdb:2XYH|rcsb pdb:2XYP|rcsb pdb:2XZD|rcsb pdb:2XZT|rcsb pdb:2Y0B|rcsb pdb:3DEH|rcsb pdb:1PAU|rcsb pdb:3DEI|rcsb pdb:3DEJ|rcsb pdb:3DEK|rcsb pdb:3EDQ|rcsb pdb:3GJQ|rcsb pdb:3GJS|rcsb pdb:3GJT|rcsb pdb:3H0E|rcsb pdb:3ITN|rcsb pdb:3KJF|rcsb pdb:3PCX|rcsb pdb:3PD0|rcsb pdb:3PD1|rcsb pdb:4DCJ|rcsb pdb:4DCO|rcsb pdb:4DCP|rcsb pdb:4EHA|rcsb pdb:4EHD|rcsb pdb:4EHF|rcsb pdb:4EHH|rcsb pdb:4EHK|rcsb pdb:4EHL|rcsb pdb:4EHN|rcsb pdb:4JJE|rcsb pdb:4JQY|rcsb pdb:4JQZ|rcsb pdb:4JR0|rcsb pdb:4PRY|rcsb pdb:4PS0|rcsb pdb:4QTX|rcsb pdb:3GJR|rcsb pdb:4QTY|rcsb pdb:4QU0|rcsb pdb:4QU5|rcsb pdb:4QU8|rcsb pdb:4QU9|rcsb pdb:4QUA|rcsb pdb:4QUB|refseq:XP_011530603.1|refseq:NP_004337.2|refseq:NP_116786.1|dip:DIP-268N psi-mi:"MI:0465"(dip) comment:mint|function:Component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells. Promotes differentiation of myogenic cells. Required for response to NTN3 and activation of NFATC3 - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:GYx35GRWYwplerMIaopmyqHx6Jw10090 rogid:o7/WP52saFha1/FD2z1rIgVLDfI9606 rigid:8vnL6WWOWtZ/SQBoHLnP8K2LbmQ false sufficient binding region:984-1250|35s radiolabel:?-?|mutation decreasing interaction rate:1153-1153|mutation decreasing interaction rate:1153-1153,1095-1095|mutation decreasing interaction rate:1164-1164,1153-1153 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)