#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P25588	uniprotkb:P32485	intact:EBI-412442|uniprotkb:P25589|uniprotkb:P27513|uniprotkb:P87003|uniprotkb:Q07218|uniprotkb:Q8NIN2|uniprotkb:D6VQV6|ensemblfungi:YCL061C	intact:EBI-8437|uniprotkb:Q06232|uniprotkb:Q12294|uniprotkb:D6VYB1|ensemblfungi:YLR113W	psi-mi:mrc1_yeast(display_long)|uniprotkb:MRC1(gene name)|psi-mi:MRC1(display_short)|uniprotkb:YCL061C(locus name)|uniprotkb:YCL61C/YCL60C(orf name)|uniprotkb:DNA replication checkpoint mediator MRC1(gene name synonym)	psi-mi:hog1_yeast(display_long)|uniprotkb:HOG1(gene name)|psi-mi:HOG1(display_short)|uniprotkb:SSK3(gene name synonym)|uniprotkb:YLR113W(locus name)|uniprotkb:L2931(orf name)|uniprotkb:L9354.2(orf name)|uniprotkb:High osmolarity glycerol response protein 1(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Duch et al. (2013)	pubmed:23178807|doi:10.1038/nature11675|imex:IM-20766	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16024567|imex:IM-20766-1|dip:DIP-190459E	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009871.2|sgd:S000000566|ensemblfungi:YCL061C(gene)|ensemblfungi:YCL061C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0034399"(nuclear periphery)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|interpro:IPR018564|go:"GO:0000723"(telomere maintenance)|mint:P25588|dip:DIP-1017N	refseq:NP_013214.1|sgd:S000004103|dip:DIP-1558N|mint:P32485|ensemblfungi:YLR113W_mRNA(transcript)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008352(MAP kinase, p38)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR038783|reactome:R-SCE-168638|reactome:R-SCE-193648|reactome:R-SCE-198753|reactome:R-SCE-2559580|reactome:R-SCE-2871796|reactome:R-SCE-418592|reactome:R-SCE-432142|reactome:R-SCE-450321|reactome:R-SCE-450341|reactome:R-SCE-525793|reactome:R-SCE-6798695|reactome:R-SCE-9007892|ensemblfungi:YLR113W(gene)	psi-mi:"MI:0465"(dip)	crc64:378345EE503FFA81	crc64:D95A20242587CE06	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:Sv9pZwka0vVslquPGLQ2N/R7W/w559292	rogid:Re8xLAJEvP2Fjr0lOGtLB6ANybM559292	rigid:QsnKkYukfF7FvKlG6XWb6CLLFbM	false	mutation disrupting interaction rate:229-229,215-215,169-169	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P25588	uniprotkb:P32485	intact:EBI-412442|uniprotkb:P25589|uniprotkb:P27513|uniprotkb:P87003|uniprotkb:Q07218|uniprotkb:Q8NIN2|uniprotkb:D6VQV6|ensemblfungi:YCL061C	intact:EBI-8437|uniprotkb:Q06232|uniprotkb:Q12294|uniprotkb:D6VYB1|ensemblfungi:YLR113W	psi-mi:mrc1_yeast(display_long)|uniprotkb:MRC1(gene name)|psi-mi:MRC1(display_short)|uniprotkb:YCL061C(locus name)|uniprotkb:YCL61C/YCL60C(orf name)|uniprotkb:DNA replication checkpoint mediator MRC1(gene name synonym)	psi-mi:hog1_yeast(display_long)|uniprotkb:HOG1(gene name)|psi-mi:HOG1(display_short)|uniprotkb:SSK3(gene name synonym)|uniprotkb:YLR113W(locus name)|uniprotkb:L2931(orf name)|uniprotkb:L9354.2(orf name)|uniprotkb:High osmolarity glycerol response protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Duch et al. (2013)	pubmed:23178807|doi:10.1038/nature11675|imex:IM-20766	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16024610|imex:IM-20766-3|dip:DIP-190459E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009871.2|sgd:S000000566|ensemblfungi:YCL061C(gene)|ensemblfungi:YCL061C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0034399"(nuclear periphery)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|interpro:IPR018564|go:"GO:0000723"(telomere maintenance)|mint:P25588|dip:DIP-1017N	refseq:NP_013214.1|sgd:S000004103|dip:DIP-1558N|mint:P32485|ensemblfungi:YLR113W_mRNA(transcript)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008352(MAP kinase, p38)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR038783|reactome:R-SCE-168638|reactome:R-SCE-193648|reactome:R-SCE-198753|reactome:R-SCE-2559580|reactome:R-SCE-2871796|reactome:R-SCE-418592|reactome:R-SCE-432142|reactome:R-SCE-450321|reactome:R-SCE-450341|reactome:R-SCE-525793|reactome:R-SCE-6798695|reactome:R-SCE-9007892|ensemblfungi:YLR113W(gene)	psi-mi:"MI:0465"(dip)	crc64:378345EE503FFA81	crc64:D95A20242587CE06	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/07	2017/08/10	rogid:Sv9pZwka0vVslquPGLQ2N/R7W/w559292	rogid:Re8xLAJEvP2Fjr0lOGtLB6ANybM559292	rigid:QsnKkYukfF7FvKlG6XWb6CLLFbM	false	tandem tag:c-c	ha tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P25588	uniprotkb:P32485	intact:EBI-412442|uniprotkb:P25589|uniprotkb:P27513|uniprotkb:P87003|uniprotkb:Q07218|uniprotkb:Q8NIN2|uniprotkb:D6VQV6|ensemblfungi:YCL061C	intact:EBI-8437|uniprotkb:Q06232|uniprotkb:Q12294|uniprotkb:D6VYB1|ensemblfungi:YLR113W	psi-mi:mrc1_yeast(display_long)|uniprotkb:MRC1(gene name)|psi-mi:MRC1(display_short)|uniprotkb:YCL061C(locus name)|uniprotkb:YCL61C/YCL60C(orf name)|uniprotkb:DNA replication checkpoint mediator MRC1(gene name synonym)	psi-mi:hog1_yeast(display_long)|uniprotkb:HOG1(gene name)|psi-mi:HOG1(display_short)|uniprotkb:SSK3(gene name synonym)|uniprotkb:YLR113W(locus name)|uniprotkb:L2931(orf name)|uniprotkb:L9354.2(orf name)|uniprotkb:High osmolarity glycerol response protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Duch et al. (2013)	pubmed:23178807|doi:10.1038/nature11675|imex:IM-20766	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16024631|imex:IM-20766-4|dip:DIP-190459E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009871.2|sgd:S000000566|ensemblfungi:YCL061C(gene)|ensemblfungi:YCL061C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0034399"(nuclear periphery)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|interpro:IPR018564|go:"GO:0000723"(telomere maintenance)|mint:P25588|dip:DIP-1017N	refseq:NP_013214.1|sgd:S000004103|dip:DIP-1558N|mint:P32485|ensemblfungi:YLR113W_mRNA(transcript)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008352(MAP kinase, p38)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR038783|reactome:R-SCE-168638|reactome:R-SCE-193648|reactome:R-SCE-198753|reactome:R-SCE-2559580|reactome:R-SCE-2871796|reactome:R-SCE-418592|reactome:R-SCE-432142|reactome:R-SCE-450321|reactome:R-SCE-450341|reactome:R-SCE-525793|reactome:R-SCE-6798695|reactome:R-SCE-9007892|ensemblfungi:YLR113W(gene)	psi-mi:"MI:0465"(dip)	crc64:378345EE503FFA81	crc64:D95A20242587CE06	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/07	2017/08/10	rogid:Sv9pZwka0vVslquPGLQ2N/R7W/w559292	rogid:Re8xLAJEvP2Fjr0lOGtLB6ANybM559292	rigid:QsnKkYukfF7FvKlG6XWb6CLLFbM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P24482	uniprotkb:P21951	intact:EBI-6071|uniprotkb:Q06622|uniprotkb:D6W4H6|ensemblfungi:YPR175W	intact:EBI-6140|uniprotkb:D6W0T1|ensemblfungi:YNL262W	psi-mi:dpb2_yeast(display_long)|uniprotkb:DPB2(gene name)|psi-mi:DPB2(display_short)|uniprotkb:YPR175W(locus name)|uniprotkb:P9705.7(orf name)|uniprotkb:DNA polymerase II subunit 2(gene name synonym)	psi-mi:dpoe_yeast(display_long)|uniprotkb:POL2(gene name)|psi-mi:POL2(display_short)|uniprotkb:DUN2(gene name synonym)|uniprotkb:YNL262W(locus name)|uniprotkb:N0825(orf name)|uniprotkb:DNA polymerase II subunit A(gene name synonym)|uniprotkb:3'-5' exodeoxyribonuclease(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Duch et al. (2013)	pubmed:23178807|doi:10.1038/nature11675|imex:IM-20766	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16024648|imex:IM-20766-5|dip:DIP-3231E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015501.2|sgd:S000006379|dip:DIP-2533N|mint:P24482|ensemblfungi:YPR175W(gene)|ensemblfungi:YPR175W_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0007049"(cell cycle)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0045005"(DNA-dependent DNA replication maintenance of fidelity)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|interpro:IPR016266(DNA polymerase epsilon, subunit B)|rcsb pdb:6HV8|rcsb pdb:6HV9|rcsb pdb:6WJV|reactome:R-SCE-5656169|reactome:R-SCE-6782135|reactome:R-SCE-68952|reactome:R-SCE-68962	refseq:NP_014137.1|sgd:S000005206|dip:DIP-2532N|mint:P21951|ensemblfungi:YNL262W(gene)|ensemblfungi:YNL262W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005657"(replication fork)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006284"(base-excision repair)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008310"(single-stranded DNA 3'-5' exodeoxyribonuclease activity)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0032183"(SUMO binding)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0035822"(gene conversion)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0045004"(DNA replication proofreading)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR013697(Region of unknown function DUF1744)|interpro:IPR029703|interpro:IPR036397|interpro:IPR042087|interpro:IPR043502|rcsb pdb:4M8O|rcsb pdb:4PTF|rcsb pdb:5OKI|rcsb pdb:6FWK|rcsb pdb:6G0A|rcsb pdb:6H1V|rcsb pdb:6HV8|rcsb pdb:6HV9|rcsb pdb:6I8A|rcsb pdb:6QIB|rcsb pdb:6S1C|rcsb pdb:6S2E|rcsb pdb:6S2F|rcsb pdb:6WJV|reactome:R-SCE-5656169|reactome:R-SCE-6782135|reactome:R-SCE-68952|reactome:R-SCE-68962	psi-mi:"MI:0465"(dip)	crc64:0936E3FC90552788	crc64:CBCDDE2AB147D65B	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/07	2017/08/10	rogid:jKBQrq2Ly8tCccOCiAcF1nfO87I559292	rogid:2OXq7Xt5TAcYf7QLOpKzpol96sE559292	rigid:999VJ/1pz7Wa2bh65eOSGoydRSU	false	flag tag:c-c	ha tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P25588	uniprotkb:P32485	intact:EBI-412442|uniprotkb:P25589|uniprotkb:P27513|uniprotkb:P87003|uniprotkb:Q07218|uniprotkb:Q8NIN2|uniprotkb:D6VQV6|ensemblfungi:YCL061C	intact:EBI-8437|uniprotkb:Q06232|uniprotkb:Q12294|uniprotkb:D6VYB1|ensemblfungi:YLR113W	psi-mi:mrc1_yeast(display_long)|uniprotkb:MRC1(gene name)|psi-mi:MRC1(display_short)|uniprotkb:YCL061C(locus name)|uniprotkb:YCL61C/YCL60C(orf name)|uniprotkb:DNA replication checkpoint mediator MRC1(gene name synonym)	psi-mi:hog1_yeast(display_long)|uniprotkb:HOG1(gene name)|psi-mi:HOG1(display_short)|uniprotkb:SSK3(gene name synonym)|uniprotkb:YLR113W(locus name)|uniprotkb:L2931(orf name)|uniprotkb:L9354.2(orf name)|uniprotkb:High osmolarity glycerol response protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Duch et al. (2013)	pubmed:23178807|doi:10.1038/nature11675|imex:IM-20766	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16024669|imex:IM-20766-6|dip:DIP-190459E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009871.2|sgd:S000000566|ensemblfungi:YCL061C(gene)|ensemblfungi:YCL061C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0034399"(nuclear periphery)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|interpro:IPR018564|go:"GO:0000723"(telomere maintenance)|mint:P25588|dip:DIP-1017N	refseq:NP_013214.1|sgd:S000004103|dip:DIP-1558N|mint:P32485|ensemblfungi:YLR113W_mRNA(transcript)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008352(MAP kinase, p38)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR038783|reactome:R-SCE-168638|reactome:R-SCE-193648|reactome:R-SCE-198753|reactome:R-SCE-2559580|reactome:R-SCE-2871796|reactome:R-SCE-418592|reactome:R-SCE-432142|reactome:R-SCE-450321|reactome:R-SCE-450341|reactome:R-SCE-525793|reactome:R-SCE-6798695|reactome:R-SCE-9007892|ensemblfungi:YLR113W(gene)	psi-mi:"MI:0465"(dip)	crc64:378345EE503FFA81	crc64:D95A20242587CE06	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/07	2017/08/10	rogid:Sv9pZwka0vVslquPGLQ2N/R7W/w559292	rogid:Re8xLAJEvP2Fjr0lOGtLB6ANybM559292	rigid:QsnKkYukfF7FvKlG6XWb6CLLFbM	false	tandem tag:c-c	ha tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P24482	uniprotkb:P25588	intact:EBI-6071|uniprotkb:Q06622|uniprotkb:D6W4H6|ensemblfungi:YPR175W	intact:EBI-412442|uniprotkb:P25589|uniprotkb:P27513|uniprotkb:P87003|uniprotkb:Q07218|uniprotkb:Q8NIN2|uniprotkb:D6VQV6|ensemblfungi:YCL061C	psi-mi:dpb2_yeast(display_long)|uniprotkb:DPB2(gene name)|psi-mi:DPB2(display_short)|uniprotkb:YPR175W(locus name)|uniprotkb:P9705.7(orf name)|uniprotkb:DNA polymerase II subunit 2(gene name synonym)	psi-mi:mrc1_yeast(display_long)|uniprotkb:MRC1(gene name)|psi-mi:MRC1(display_short)|uniprotkb:YCL061C(locus name)|uniprotkb:YCL61C/YCL60C(orf name)|uniprotkb:DNA replication checkpoint mediator MRC1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Duch et al. (2013)	pubmed:23178807|doi:10.1038/nature11675|imex:IM-20766	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16024589|imex:IM-20766-2|dip:DIP-190461E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015501.2|sgd:S000006379|dip:DIP-2533N|mint:P24482|ensemblfungi:YPR175W(gene)|ensemblfungi:YPR175W_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0007049"(cell cycle)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0045005"(DNA-dependent DNA replication maintenance of fidelity)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|interpro:IPR016266(DNA polymerase epsilon, subunit B)|rcsb pdb:6HV8|rcsb pdb:6HV9|rcsb pdb:6WJV|reactome:R-SCE-5656169|reactome:R-SCE-6782135|reactome:R-SCE-68952|reactome:R-SCE-68962	refseq:NP_009871.2|sgd:S000000566|ensemblfungi:YCL061C(gene)|ensemblfungi:YCL061C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0034399"(nuclear periphery)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|interpro:IPR018564|go:"GO:0000723"(telomere maintenance)|mint:P25588|dip:DIP-1017N	psi-mi:"MI:0465"(dip)	crc64:0936E3FC90552788	crc64:378345EE503FFA81	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/07	2017/08/10	rogid:jKBQrq2Ly8tCccOCiAcF1nfO87I559292	rogid:Sv9pZwka0vVslquPGLQ2N/R7W/w559292	rigid:WUTbxtG1sbhZQpAGulRuS8mHsMQ	false	ha tag:c-c	myc tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P21951	uniprotkb:P25588	intact:EBI-6140|uniprotkb:D6W0T1|ensemblfungi:YNL262W	intact:EBI-412442|uniprotkb:P25589|uniprotkb:P27513|uniprotkb:P87003|uniprotkb:Q07218|uniprotkb:Q8NIN2|uniprotkb:D6VQV6|ensemblfungi:YCL061C	psi-mi:dpoe_yeast(display_long)|uniprotkb:POL2(gene name)|psi-mi:POL2(display_short)|uniprotkb:DUN2(gene name synonym)|uniprotkb:YNL262W(locus name)|uniprotkb:N0825(orf name)|uniprotkb:DNA polymerase II subunit A(gene name synonym)|uniprotkb:3'-5' exodeoxyribonuclease(gene name synonym)	psi-mi:mrc1_yeast(display_long)|uniprotkb:MRC1(gene name)|psi-mi:MRC1(display_short)|uniprotkb:YCL061C(locus name)|uniprotkb:YCL61C/YCL60C(orf name)|uniprotkb:DNA replication checkpoint mediator MRC1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Duch et al. (2013)	pubmed:23178807|doi:10.1038/nature11675|imex:IM-20766	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16024690|imex:IM-20766-7|dip:DIP-190460E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014137.1|sgd:S000005206|dip:DIP-2532N|mint:P21951|ensemblfungi:YNL262W(gene)|ensemblfungi:YNL262W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005657"(replication fork)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006284"(base-excision repair)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008310"(single-stranded DNA 3'-5' exodeoxyribonuclease activity)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0032183"(SUMO binding)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0035822"(gene conversion)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0045004"(DNA replication proofreading)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR013697(Region of unknown function DUF1744)|interpro:IPR029703|interpro:IPR036397|interpro:IPR042087|interpro:IPR043502|rcsb pdb:4M8O|rcsb pdb:4PTF|rcsb pdb:5OKI|rcsb pdb:6FWK|rcsb pdb:6G0A|rcsb pdb:6H1V|rcsb pdb:6HV8|rcsb pdb:6HV9|rcsb pdb:6I8A|rcsb pdb:6QIB|rcsb pdb:6S1C|rcsb pdb:6S2E|rcsb pdb:6S2F|rcsb pdb:6WJV|reactome:R-SCE-5656169|reactome:R-SCE-6782135|reactome:R-SCE-68952|reactome:R-SCE-68962	refseq:NP_009871.2|sgd:S000000566|ensemblfungi:YCL061C(gene)|ensemblfungi:YCL061C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0034399"(nuclear periphery)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|interpro:IPR018564|go:"GO:0000723"(telomere maintenance)|mint:P25588|dip:DIP-1017N	psi-mi:"MI:0465"(dip)	crc64:CBCDDE2AB147D65B	crc64:378345EE503FFA81	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/07	2017/08/10	rogid:2OXq7Xt5TAcYf7QLOpKzpol96sE559292	rogid:Sv9pZwka0vVslquPGLQ2N/R7W/w559292	rigid:I3v5pP66IYLqRoZp/RnyyUBuvZg	false	ha tag:c-c	myc tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)