#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P12081	uniprotkb:P12081	intact:EBI-1057566|uniprotkb:B4DY73|uniprotkb:B4DHQ1|uniprotkb:D6REN6|uniprotkb:J3KNE5|ensembl:ENSP00000425634	intact:EBI-1057566|uniprotkb:B4DY73|uniprotkb:B4DHQ1|uniprotkb:D6REN6|uniprotkb:J3KNE5|ensembl:ENSP00000425634	psi-mi:hars1_human(display_long)|uniprotkb:HARS1(gene name)|psi-mi:HARS1(display_short)|uniprotkb:HARS(gene name synonym)|uniprotkb:HRS(gene name synonym)|uniprotkb:Histidyl-tRNA synthetase(gene name synonym)	psi-mi:hars1_human(display_long)|uniprotkb:HARS1(gene name)|psi-mi:HARS1(display_short)|uniprotkb:HARS(gene name synonym)|uniprotkb:HRS(gene name synonym)|uniprotkb:Histidyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Xu et al. (2012)	pubmed:22958643|doi:10.1016/j.str.2012.08.001|imex:IM-18043	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16013045|imex:IM-18043-1|dip:DIP-189644E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001244969.1|refseq:NP_002100.2|refseq:NP_001244970.1|refseq:NP_001244971.1|ensembl:ENSG00000170445(gene)|ensembl:ENST00000504156(transcript)|go:"GO:0004821"(histidine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006427"(histidyl-tRNA aminoacylation)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR000738(WHEP-TRS)|interpro:IPR004154(Anticodon-binding)|interpro:IPR004516(Histidyl-tRNA synthetase, class IIa)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR015807(Histidyl-tRNA synthetase, class IIa, subgroup)|interpro:IPR033656|interpro:IPR036621|interpro:IPR041715|mint:P12081|rcsb pdb:1X59|rcsb pdb:2LW7|rcsb pdb:4G84|rcsb pdb:4G85|rcsb pdb:4PHC|rcsb pdb:4X5O|rcsb pdb:5W6M|rcsb pdb:6O76|reactome:R-HSA-379716|dip:DIP-37596N	refseq:NP_001244969.1|refseq:NP_002100.2|refseq:NP_001244970.1|refseq:NP_001244971.1|ensembl:ENSG00000170445(gene)|ensembl:ENST00000504156(transcript)|go:"GO:0004821"(histidine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006427"(histidyl-tRNA aminoacylation)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR000738(WHEP-TRS)|interpro:IPR004154(Anticodon-binding)|interpro:IPR004516(Histidyl-tRNA synthetase, class IIa)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR015807(Histidyl-tRNA synthetase, class IIa, subgroup)|interpro:IPR033656|interpro:IPR036621|interpro:IPR041715|mint:P12081|rcsb pdb:1X59|rcsb pdb:2LW7|rcsb pdb:4G84|rcsb pdb:4G85|rcsb pdb:4PHC|rcsb pdb:4X5O|rcsb pdb:5W6M|rcsb pdb:6O76|reactome:R-HSA-379716|dip:DIP-37596N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/07	2017/08/10	rogid:7o34bzWC+/C+mlCDTcvUOHbaCxE9606	rogid:7o34bzWC+/C+mlCDTcvUOHbaCxE9606	rigid:QaceKwVWxksLW9uGImrejLX8m+s	false	necessary binding region:61-398|sufficient binding region:54-506	necessary binding region:61-398|sufficient binding region:54-506	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P12081	uniprotkb:P12081	intact:EBI-1057566|uniprotkb:B4DY73|uniprotkb:B4DHQ1|uniprotkb:D6REN6|uniprotkb:J3KNE5|ensembl:ENSP00000425634	intact:EBI-1057566|uniprotkb:B4DY73|uniprotkb:B4DHQ1|uniprotkb:D6REN6|uniprotkb:J3KNE5|ensembl:ENSP00000425634	psi-mi:hars1_human(display_long)|uniprotkb:HARS1(gene name)|psi-mi:HARS1(display_short)|uniprotkb:HARS(gene name synonym)|uniprotkb:HRS(gene name synonym)|uniprotkb:Histidyl-tRNA synthetase(gene name synonym)	psi-mi:hars1_human(display_long)|uniprotkb:HARS1(gene name)|psi-mi:HARS1(display_short)|uniprotkb:HARS(gene name synonym)|uniprotkb:HRS(gene name synonym)|uniprotkb:Histidyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Xu et al. (2012)	pubmed:22958643|doi:10.1016/j.str.2012.08.001|imex:IM-18043	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16013067|imex:IM-18043-2|dip:DIP-189644E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001244969.1|refseq:NP_002100.2|refseq:NP_001244970.1|refseq:NP_001244971.1|ensembl:ENSG00000170445(gene)|ensembl:ENST00000504156(transcript)|go:"GO:0004821"(histidine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006427"(histidyl-tRNA aminoacylation)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR000738(WHEP-TRS)|interpro:IPR004154(Anticodon-binding)|interpro:IPR004516(Histidyl-tRNA synthetase, class IIa)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR015807(Histidyl-tRNA synthetase, class IIa, subgroup)|interpro:IPR033656|interpro:IPR036621|interpro:IPR041715|mint:P12081|rcsb pdb:1X59|rcsb pdb:2LW7|rcsb pdb:4G84|rcsb pdb:4G85|rcsb pdb:4PHC|rcsb pdb:4X5O|rcsb pdb:5W6M|rcsb pdb:6O76|reactome:R-HSA-379716|dip:DIP-37596N	refseq:NP_001244969.1|refseq:NP_002100.2|refseq:NP_001244970.1|refseq:NP_001244971.1|ensembl:ENSG00000170445(gene)|ensembl:ENST00000504156(transcript)|go:"GO:0004821"(histidine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006427"(histidyl-tRNA aminoacylation)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR000738(WHEP-TRS)|interpro:IPR004154(Anticodon-binding)|interpro:IPR004516(Histidyl-tRNA synthetase, class IIa)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR015807(Histidyl-tRNA synthetase, class IIa, subgroup)|interpro:IPR033656|interpro:IPR036621|interpro:IPR041715|mint:P12081|rcsb pdb:1X59|rcsb pdb:2LW7|rcsb pdb:4G84|rcsb pdb:4G85|rcsb pdb:4PHC|rcsb pdb:4X5O|rcsb pdb:5W6M|rcsb pdb:6O76|reactome:R-HSA-379716|dip:DIP-37596N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/07	2017/08/10	rogid:7o34bzWC+/C+mlCDTcvUOHbaCxE9606	rogid:7o34bzWC+/C+mlCDTcvUOHbaCxE9606	rigid:QaceKwVWxksLW9uGImrejLX8m+s	false	sufficient binding region:54-506	sufficient binding region:54-506	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)