#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P03366-PRO_0000042285	uniprotkb:P25025	intact:EBI-16008897|dip:DIP-60325N|dip:DIP-40755N	intact:EBI-2835281|uniprotkb:Q8IUZ1|uniprotkb:Q9P2T7|uniprotkb:Q9P2T6|ensembl:ENSP00000319635	psi-mi:pro_0000042285(display_long)|uniprotkb:gag-pol(gene name)|psi-mi:gag-pol(display_short)	psi-mi:cxcr2_human(display_long)|uniprotkb:CXCR2(gene name)|psi-mi:CXCR2(display_short)|uniprotkb:IL8RB(gene name synonym)|uniprotkb:CDw128b(gene name synonym)|uniprotkb:GRO/MGSA receptor(gene name synonym)|uniprotkb:High affinity interleukin-8 receptor B(gene name synonym)|uniprotkb:IL-8 receptor type 2(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Caccuri et al. (2012)	pubmed:22904195|doi:10.1073/pnas.1206605109|imex:IM-21277	taxid:11678(hv1b1)|taxid:11678("Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16008905|imex:IM-21277-1|dip:DIP-191238E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:P03366(chain-parent)	ensembl:ENSG00000180871(gene)|ensembl:ENST00000318507(transcript)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0002438"(acute inflammatory response to antigenic stimulus)|go:"GO:0004918"(interleukin-8 receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008284"(positive regulation of cell population proliferation)|refseq:NP_001161770.1|refseq:NP_001548.1|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0019959"(interleukin-8 binding)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030901"(midbrain development)|go:"GO:0031623"(receptor internalization)|go:"GO:0033030"(negative regulation of neutrophil apoptotic process)|go:"GO:0038112"(interleukin-8-mediated signaling pathway)|go:"GO:0042119"(neutrophil activation)|go:"GO:0042629"(mast cell granule)|go:"GO:0043117"(positive regulation of vascular permeability)|refseq:XP_005246587.1|go:"GO:0060326"(cell chemotaxis)|go:"GO:0072173"(metanephric tubule morphogenesis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|interpro:IPR000057(Interleukin 8B receptor)|interpro:IPR000174(Interleukin-8 receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|go:"GO:0045766"(positive regulation of angiogenesis)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:4Q3H|rcsb pdb:5TYT|rcsb pdb:6KVA|rcsb pdb:6KVF|rcsb pdb:6LFM|rcsb pdb:6LFO|reactome:R-HSA-380108|reactome:R-HSA-418594|reactome:R-HSA-6798695|refseq:XP_016859479.1|refseq:XP_016859480.1|refseq:XP_016859481.1|dip:DIP-3782N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:RmJF0HVZxAO6UXqTc3CrxUF/h+k11678	rogid:T16V0LpaqMIhUJlknnqmSVxX39o9606	rigid:bMHFNBxWRFBEIBZTk5BrZdVjCvM	false	polyprotein fragment:2-132	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10145	uniprotkb:P25025	intact:EBI-3917999|uniprotkb:Q9UCS0|uniprotkb:Q9UCR8|uniprotkb:Q9C077|uniprotkb:Q6FGF6|uniprotkb:Q96RG6|uniprotkb:B2R4L8|uniprotkb:Q9UCE1|uniprotkb:Q9UCR9|uniprotkb:Q6LAE6|ensembl:ENSP00000306512	intact:EBI-2835281|uniprotkb:Q8IUZ1|uniprotkb:Q9P2T7|uniprotkb:Q9P2T6|ensembl:ENSP00000319635	psi-mi:il8_human(display_long)|uniprotkb:Protein 3-10C(gene name synonym)|uniprotkb:T-cell chemotactic factor(gene name synonym)|uniprotkb:CXCL8(gene name)|psi-mi:CXCL8(display_short)|uniprotkb:C-X-C motif chemokine 8(gene name synonym)|uniprotkb:"Chemokine (C-X-C motif) ligand 8"(gene name synonym)|uniprotkb:Emoctakin(gene name synonym)|uniprotkb:Granulocyte chemotactic protein 1(gene name synonym)|uniprotkb:IL8(gene name synonym)|uniprotkb:Monocyte-derived neutrophil chemotactic factor(gene name synonym)|uniprotkb:Monocyte-derived neutrophil-activating peptide(gene name synonym)|uniprotkb:Neutrophil-activating protein 1(gene name synonym)	psi-mi:cxcr2_human(display_long)|uniprotkb:CXCR2(gene name)|psi-mi:CXCR2(display_short)|uniprotkb:IL8RB(gene name synonym)|uniprotkb:CDw128b(gene name synonym)|uniprotkb:GRO/MGSA receptor(gene name synonym)|uniprotkb:High affinity interleukin-8 receptor B(gene name synonym)|uniprotkb:IL-8 receptor type 2(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Caccuri et al. (2012)	pubmed:22904195|doi:10.1073/pnas.1206605109|imex:IM-21277	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16008927|imex:IM-21277-2|dip:DIP-5748E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000575.1|ensembl:ENSG00000169429(gene)|ensembl:ENST00000307407(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0002237"(response to molecule of bacterial origin)|go:"GO:0005153"(interleukin-8 receptor binding)|go:"GO:0005576"(extracellular region)|reactome:R-HSA-6785807|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008009"(chemokine activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031328"(positive regulation of cellular biosynthetic process)|go:"GO:0031623"(receptor internalization)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042119"(neutrophil activation)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045091"(regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045236"(CXCR chemokine receptor binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048566"(embryonic digestive tract development)|go:"GO:0050930"(induction of positive chemotaxis)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0006935"(chemotaxis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070098"(chemokine-mediated signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:2000535"(regulation of entry of bacterium into host cell)|interpro:IPR001089(Small chemokine, C-X-C)|interpro:IPR001811(Small chemokine, interleukin-8-like)|interpro:IPR018048|interpro:IPR028469|interpro:IPR033899|interpro:IPR036048|rcsb pdb:1ICW|rcsb pdb:1IKL|rcsb pdb:1IKM|rcsb pdb:1IL8|go:"GO:0060354"(negative regulation of cell adhesion molecule production)|rcsb pdb:1ILQ|rcsb pdb:1QE6|rcsb pdb:1ROD|rcsb pdb:2IL8|rcsb pdb:3IL8|rcsb pdb:4XDX|rcsb pdb:5D14|rcsb pdb:5WDZ|rcsb pdb:6LFM|rcsb pdb:6LFO|rcsb pdb:6N2U|rcsb pdb:6WZM|reactome:R-HSA-2559582|reactome:R-HSA-375276|rcsb pdb:1ILP|reactome:R-HSA-380108|reactome:R-HSA-380994|reactome:R-HSA-418594|reactome:R-HSA-6783783|dip:DIP-3778N	ensembl:ENSG00000180871(gene)|ensembl:ENST00000318507(transcript)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0002438"(acute inflammatory response to antigenic stimulus)|go:"GO:0004918"(interleukin-8 receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008284"(positive regulation of cell population proliferation)|refseq:NP_001161770.1|refseq:NP_001548.1|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0019959"(interleukin-8 binding)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030901"(midbrain development)|go:"GO:0031623"(receptor internalization)|go:"GO:0033030"(negative regulation of neutrophil apoptotic process)|go:"GO:0038112"(interleukin-8-mediated signaling pathway)|go:"GO:0042119"(neutrophil activation)|go:"GO:0042629"(mast cell granule)|go:"GO:0043117"(positive regulation of vascular permeability)|refseq:XP_005246587.1|go:"GO:0060326"(cell chemotaxis)|go:"GO:0072173"(metanephric tubule morphogenesis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|interpro:IPR000057(Interleukin 8B receptor)|interpro:IPR000174(Interleukin-8 receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|go:"GO:0045766"(positive regulation of angiogenesis)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:4Q3H|rcsb pdb:5TYT|rcsb pdb:6KVA|rcsb pdb:6KVF|rcsb pdb:6LFM|rcsb pdb:6LFO|reactome:R-HSA-380108|reactome:R-HSA-418594|reactome:R-HSA-6798695|refseq:XP_016859479.1|refseq:XP_016859480.1|refseq:XP_016859481.1|dip:DIP-3782N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:aC4GQA1hEtGxhjdfmoeStVe8Mf09606	rogid:T16V0LpaqMIhUJlknnqmSVxX39o9606	rigid:e4uyUXs6BKclebixsy3U0ow4peY	false	sufficient binding region:28-99	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)