#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O14931 uniprotkb:O14931 intact:EBI-14989262|ensembl:ENSP00000416035|ensembl:ENSP00000416944|ensembl:ENSP00000342156|ensembl:ENSP00000372969|ensembl:ENSP00000389071|ensembl:ENSP00000390131|ensembl:ENSP00000398313|ensembl:ENSP00000405306|uniprotkb:B0S8F2|uniprotkb:B0S8F4|uniprotkb:B0S8F5|uniprotkb:O14930|uniprotkb:O14932|uniprotkb:O95667|uniprotkb:O95668|uniprotkb:O95669|uniprotkb:Q5ST89|uniprotkb:Q5ST90|uniprotkb:Q5ST91|uniprotkb:Q5ST92|uniprotkb:Q5STA3 intact:EBI-14989262|ensembl:ENSP00000416035|ensembl:ENSP00000416944|ensembl:ENSP00000342156|ensembl:ENSP00000372969|ensembl:ENSP00000389071|ensembl:ENSP00000390131|ensembl:ENSP00000398313|ensembl:ENSP00000405306|uniprotkb:B0S8F2|uniprotkb:B0S8F4|uniprotkb:B0S8F5|uniprotkb:O14930|uniprotkb:O14932|uniprotkb:O95667|uniprotkb:O95668|uniprotkb:O95669|uniprotkb:Q5ST89|uniprotkb:Q5ST90|uniprotkb:Q5ST91|uniprotkb:Q5ST92|uniprotkb:Q5STA3 psi-mi:nctr3_human(display_long)|uniprotkb:NCR3(gene name)|psi-mi:NCR3(display_short)|uniprotkb:1C7(gene name synonym)|uniprotkb:LY117(gene name synonym)|uniprotkb:Activating natural killer receptor p30(gene name synonym)|uniprotkb:Natural killer cell p30-related protein(gene name synonym) psi-mi:nctr3_human(display_long)|uniprotkb:NCR3(gene name)|psi-mi:NCR3(display_short)|uniprotkb:1C7(gene name synonym)|uniprotkb:LY117(gene name synonym)|uniprotkb:Activating natural killer receptor p30(gene name synonym)|uniprotkb:Natural killer cell p30-related protein(gene name synonym) psi-mi:"MI:0982"(electrophoretic mobility-based method) Hartmann et al. (2012) pubmed:22807449|imex:IM-26120 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-15481871|imex:IM-26120-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000204475(gene)|ensembl:ENSG00000206430(gene)|ensembl:ENSG00000223833(gene)|ensembl:ENSG00000225211(gene)|ensembl:ENSG00000236315(gene)|ensembl:ENST00000340027(transcript)|ensembl:ENST00000383477(transcript)|ensembl:ENST00000415123(transcript)|ensembl:ENST00000420556(transcript)|ensembl:ENST00000430599(transcript)|ensembl:ENST00000435674(transcript)|ensembl:ENST00000437517(transcript)|ensembl:ENST00000447248(transcript)|go:"GO:0002429"(immune response-activating cell surface receptor signaling pathway)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0008037"(cell recognition)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|interpro:IPR003599(Immunoglobulin subtype)|ensembl:ENSG00000236979(gene)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|ensembl:ENSG00000237103(gene)|ensembl:ENSG00000237808(gene)|interpro:IPR036179|interpro:IPR043226|rcsb pdb:3PV6|rcsb pdb:3NOI|rcsb pdb:6YJP|reactome:R-HSA-198933|refseq:NP_001138938.1|refseq:NP_001138939.1|refseq:NP_667341.1|refseq:XP_006715112.1|refseq:XP_011512761.1|dip:DIP-59939N ensembl:ENSG00000204475(gene)|ensembl:ENSG00000206430(gene)|ensembl:ENSG00000223833(gene)|ensembl:ENSG00000225211(gene)|ensembl:ENSG00000236315(gene)|ensembl:ENST00000340027(transcript)|ensembl:ENST00000383477(transcript)|ensembl:ENST00000415123(transcript)|ensembl:ENST00000420556(transcript)|ensembl:ENST00000430599(transcript)|ensembl:ENST00000435674(transcript)|ensembl:ENST00000437517(transcript)|ensembl:ENST00000447248(transcript)|go:"GO:0002429"(immune response-activating cell surface receptor signaling pathway)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0008037"(cell recognition)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|interpro:IPR003599(Immunoglobulin subtype)|ensembl:ENSG00000236979(gene)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|ensembl:ENSG00000237103(gene)|ensembl:ENSG00000237808(gene)|interpro:IPR036179|interpro:IPR043226|rcsb pdb:3PV6|rcsb pdb:3NOI|rcsb pdb:6YJP|reactome:R-HSA-198933|refseq:NP_001138938.1|refseq:NP_001138939.1|refseq:NP_667341.1|refseq:XP_006715112.1|refseq:XP_011512761.1|dip:DIP-59939N - - - figure legend:2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/07/10 2017/07/11 rogid:bS3R8rfddez5+tROQijf3FtslOU9606 rogid:bS3R8rfddez5+tROQijf3FtslOU9606 rigid:FzxBBXqtxy4opuOvpULys4iKqfU false fc-igg tag:c-c|sufficient binding region:19-143(IPR013783)|disulfide crosslinked residues:?-? fc-igg tag:c-c|sufficient binding region:19-143(IPR013783)|disulfide crosslinked residues:?-? 1 1 psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O14931 uniprotkb:O14931 intact:EBI-14989262|ensembl:ENSP00000416035|ensembl:ENSP00000416944|ensembl:ENSP00000342156|ensembl:ENSP00000372969|ensembl:ENSP00000389071|ensembl:ENSP00000390131|ensembl:ENSP00000398313|ensembl:ENSP00000405306|uniprotkb:B0S8F2|uniprotkb:B0S8F4|uniprotkb:B0S8F5|uniprotkb:O14930|uniprotkb:O14932|uniprotkb:O95667|uniprotkb:O95668|uniprotkb:O95669|uniprotkb:Q5ST89|uniprotkb:Q5ST90|uniprotkb:Q5ST91|uniprotkb:Q5ST92|uniprotkb:Q5STA3 intact:EBI-14989262|ensembl:ENSP00000416035|ensembl:ENSP00000416944|ensembl:ENSP00000342156|ensembl:ENSP00000372969|ensembl:ENSP00000389071|ensembl:ENSP00000390131|ensembl:ENSP00000398313|ensembl:ENSP00000405306|uniprotkb:B0S8F2|uniprotkb:B0S8F4|uniprotkb:B0S8F5|uniprotkb:O14930|uniprotkb:O14932|uniprotkb:O95667|uniprotkb:O95668|uniprotkb:O95669|uniprotkb:Q5ST89|uniprotkb:Q5ST90|uniprotkb:Q5ST91|uniprotkb:Q5ST92|uniprotkb:Q5STA3 psi-mi:nctr3_human(display_long)|uniprotkb:NCR3(gene name)|psi-mi:NCR3(display_short)|uniprotkb:1C7(gene name synonym)|uniprotkb:LY117(gene name synonym)|uniprotkb:Activating natural killer receptor p30(gene name synonym)|uniprotkb:Natural killer cell p30-related protein(gene name synonym) psi-mi:nctr3_human(display_long)|uniprotkb:NCR3(gene name)|psi-mi:NCR3(display_short)|uniprotkb:1C7(gene name synonym)|uniprotkb:LY117(gene name synonym)|uniprotkb:Activating natural killer receptor p30(gene name synonym)|uniprotkb:Natural killer cell p30-related protein(gene name synonym) psi-mi:"MI:0982"(electrophoretic mobility-based method) Hartmann et al. (2012) pubmed:22807449|imex:IM-26120 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-15481900|imex:IM-26120-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000204475(gene)|ensembl:ENSG00000206430(gene)|ensembl:ENSG00000223833(gene)|ensembl:ENSG00000225211(gene)|ensembl:ENSG00000236315(gene)|ensembl:ENST00000340027(transcript)|ensembl:ENST00000383477(transcript)|ensembl:ENST00000415123(transcript)|ensembl:ENST00000420556(transcript)|ensembl:ENST00000430599(transcript)|ensembl:ENST00000435674(transcript)|ensembl:ENST00000437517(transcript)|ensembl:ENST00000447248(transcript)|go:"GO:0002429"(immune response-activating cell surface receptor signaling pathway)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0008037"(cell recognition)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|interpro:IPR003599(Immunoglobulin subtype)|ensembl:ENSG00000236979(gene)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|ensembl:ENSG00000237103(gene)|ensembl:ENSG00000237808(gene)|interpro:IPR036179|interpro:IPR043226|rcsb pdb:3PV6|rcsb pdb:3NOI|rcsb pdb:6YJP|reactome:R-HSA-198933|refseq:NP_001138938.1|refseq:NP_001138939.1|refseq:NP_667341.1|refseq:XP_006715112.1|refseq:XP_011512761.1|dip:DIP-59939N ensembl:ENSG00000204475(gene)|ensembl:ENSG00000206430(gene)|ensembl:ENSG00000223833(gene)|ensembl:ENSG00000225211(gene)|ensembl:ENSG00000236315(gene)|ensembl:ENST00000340027(transcript)|ensembl:ENST00000383477(transcript)|ensembl:ENST00000415123(transcript)|ensembl:ENST00000420556(transcript)|ensembl:ENST00000430599(transcript)|ensembl:ENST00000435674(transcript)|ensembl:ENST00000437517(transcript)|ensembl:ENST00000447248(transcript)|go:"GO:0002429"(immune response-activating cell surface receptor signaling pathway)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0008037"(cell recognition)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|interpro:IPR003599(Immunoglobulin subtype)|ensembl:ENSG00000236979(gene)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|ensembl:ENSG00000237103(gene)|ensembl:ENSG00000237808(gene)|interpro:IPR036179|interpro:IPR043226|rcsb pdb:3PV6|rcsb pdb:3NOI|rcsb pdb:6YJP|reactome:R-HSA-198933|refseq:NP_001138938.1|refseq:NP_001138939.1|refseq:NP_667341.1|refseq:XP_006715112.1|refseq:XP_011512761.1|dip:DIP-59939N - - - figure legend:2C-2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/07/10 2017/07/11 rogid:bS3R8rfddez5+tROQijf3FtslOU9606 rogid:bS3R8rfddez5+tROQijf3FtslOU9606 rigid:FzxBBXqtxy4opuOvpULys4iKqfU false fc-igg tag:c-c|sufficient binding region:19-128(IPR013783)|disulfide crosslinked residues:?-? fc-igg tag:c-c|sufficient binding region:19-128(IPR013783)|disulfide crosslinked residues:?-? 1 1 psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P48551 uniprotkb:P48551 intact:EBI-958408|uniprotkb:A8KAJ4|uniprotkb:Q6FHD7|uniprotkb:D3DSE8|uniprotkb:D3DSE9|uniprotkb:Q15467|ensembl:ENSP00000343957|ensembl:ENSP00000508013 intact:EBI-958408|uniprotkb:A8KAJ4|uniprotkb:Q6FHD7|uniprotkb:D3DSE8|uniprotkb:D3DSE9|uniprotkb:Q15467|ensembl:ENSP00000343957|ensembl:ENSP00000508013 psi-mi:inar2_human(display_long)|uniprotkb:IFNAR2(gene name)|psi-mi:IFNAR2(display_short)|uniprotkb:IFNARB(gene name synonym)|uniprotkb:Type I interferon receptor 2(gene name synonym)|uniprotkb:IFNABR(gene name synonym)|uniprotkb:Interferon alpha binding protein(gene name synonym) psi-mi:inar2_human(display_long)|uniprotkb:IFNAR2(gene name)|psi-mi:IFNAR2(display_short)|uniprotkb:IFNARB(gene name synonym)|uniprotkb:Type I interferon receptor 2(gene name synonym)|uniprotkb:IFNABR(gene name synonym)|uniprotkb:Interferon alpha binding protein(gene name synonym) psi-mi:"MI:0982"(electrophoretic mobility-based method) Hartmann et al. (2012) pubmed:22807449|imex:IM-26120 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-15481918|imex:IM-26120-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000865.2|refseq:NP_997467.1|refseq:NP_997468.1|refseq:NP_001276054.1|refseq:NP_001276055.1|refseq:NP_001276057.1|dip:DIP-945N|ensembl:ENSG00000159110(gene)|ensembl:ENST00000342136(transcript)|ensembl:ENST00000683941(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0009615"(response to virus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019962"(type I interferon binding)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|interpro:IPR003961(Fibronectin, type III)|go:"GO:0004905"(type I interferon receptor activity)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015373(Interferon-alpha/beta receptor, fibronectin type III)|interpro:IPR036116|mint:P48551|rcsb pdb:1N6U|rcsb pdb:1N6V|rcsb pdb:2HYM|rcsb pdb:2KZ1|rcsb pdb:2LAG|rcsb pdb:3S8W|rcsb pdb:3S9D|rcsb pdb:3SE3|rcsb pdb:3SE4|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9679191 refseq:NP_000865.2|refseq:NP_997467.1|refseq:NP_997468.1|refseq:NP_001276054.1|refseq:NP_001276055.1|refseq:NP_001276057.1|dip:DIP-945N|ensembl:ENSG00000159110(gene)|ensembl:ENST00000342136(transcript)|ensembl:ENST00000683941(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0009615"(response to virus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019962"(type I interferon binding)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|interpro:IPR003961(Fibronectin, type III)|go:"GO:0004905"(type I interferon receptor activity)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015373(Interferon-alpha/beta receptor, fibronectin type III)|interpro:IPR036116|mint:P48551|rcsb pdb:1N6U|rcsb pdb:1N6V|rcsb pdb:2HYM|rcsb pdb:2KZ1|rcsb pdb:2LAG|rcsb pdb:3S8W|rcsb pdb:3S9D|rcsb pdb:3SE3|rcsb pdb:3SE4|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9679191 - - - figure legend:2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/07/10 2017/07/11 rogid:n9jPySJ4jlqmT6QgmSlEeNLwUog9606 rogid:n9jPySJ4jlqmT6QgmSlEeNLwUog9606 rigid:L8vUCJxRvXKen0Pzjqjn7W5rEZ0 false fc-igg tag:c-c|sufficient binding region:28-239|disulfide crosslinked residues:?-? fc-igg tag:c-c|sufficient binding region:28-239|disulfide crosslinked residues:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q68D85 uniprotkb:O14931 intact:EBI-14061804|uniprotkb:Q7Z3M6|ensembl:ENSP00000341637|ensembl:ENSP00000434394 intact:EBI-14989262|ensembl:ENSP00000416035|ensembl:ENSP00000416944|ensembl:ENSP00000342156|ensembl:ENSP00000372969|ensembl:ENSP00000389071|ensembl:ENSP00000390131|ensembl:ENSP00000398313|ensembl:ENSP00000405306|uniprotkb:B0S8F2|uniprotkb:B0S8F4|uniprotkb:B0S8F5|uniprotkb:O14930|uniprotkb:O14932|uniprotkb:O95667|uniprotkb:O95668|uniprotkb:O95669|uniprotkb:Q5ST89|uniprotkb:Q5ST90|uniprotkb:Q5ST91|uniprotkb:Q5ST92|uniprotkb:Q5STA3 psi-mi:nr3l1_human(display_long)|uniprotkb:NCR3LG1(gene name)|psi-mi:NCR3LG1(display_short)|uniprotkb:B7 homolog 6(gene name synonym)|uniprotkb:B7H6(gene name synonym) psi-mi:nctr3_human(display_long)|uniprotkb:NCR3(gene name)|psi-mi:NCR3(display_short)|uniprotkb:1C7(gene name synonym)|uniprotkb:LY117(gene name synonym)|uniprotkb:Activating natural killer receptor p30(gene name synonym)|uniprotkb:Natural killer cell p30-related protein(gene name synonym) psi-mi:"MI:0054"(fluorescence-activated cell sorting) Hartmann et al. (2012) pubmed:22807449|imex:IM-26120 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-15482652|imex:IM-26120-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001189368.1|ensembl:ENSG00000188211(gene)|ensembl:ENST00000338965(transcript)|ensembl:ENST00000530403(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR036946|rcsb pdb:3PV6|rcsb pdb:3PV7|rcsb pdb:4ZSO|rcsb pdb:6YJP|reactome:R-HSA-198933|dip:DIP-59940N ensembl:ENSG00000204475(gene)|ensembl:ENSG00000206430(gene)|ensembl:ENSG00000223833(gene)|ensembl:ENSG00000225211(gene)|ensembl:ENSG00000236315(gene)|ensembl:ENST00000340027(transcript)|ensembl:ENST00000383477(transcript)|ensembl:ENST00000415123(transcript)|ensembl:ENST00000420556(transcript)|ensembl:ENST00000430599(transcript)|ensembl:ENST00000435674(transcript)|ensembl:ENST00000437517(transcript)|ensembl:ENST00000447248(transcript)|go:"GO:0002429"(immune response-activating cell surface receptor signaling pathway)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0008037"(cell recognition)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|interpro:IPR003599(Immunoglobulin subtype)|ensembl:ENSG00000236979(gene)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|ensembl:ENSG00000237103(gene)|ensembl:ENSG00000237808(gene)|interpro:IPR036179|interpro:IPR043226|rcsb pdb:3PV6|rcsb pdb:3NOI|rcsb pdb:6YJP|reactome:R-HSA-198933|refseq:NP_001138938.1|refseq:NP_001138939.1|refseq:NP_667341.1|refseq:XP_006715112.1|refseq:XP_011512761.1|dip:DIP-59939N - - - figure legend:2G, 4B, 5B, 7C, Supp fig 3A, Supp fig 5|comment:"THe LBD (19-128) region of NKp30 also bound, but not as strongly. A NKp30 mutant containing a length-matched glycine-serine (GS) linker instead of the stalk domain gave an intermediate result as compared with 30LBD-Ig and 30Stalk-Ig constructs. Truncated NKp30-Ig constructs lost the superior ligand binding properties of the 30Stalk-Ig construct."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/07/10 2020/02/14 rogid:zxyF+bJz/qWtsilosYWPqwnDUw89606 rogid:bS3R8rfddez5+tROQijf3FtslOU9606 rigid:RGs60g1CS7VjnF4PJeDm9zXbysI false - mutation disrupting interaction strength:42-42|fc-igg tag:c-c|sufficient binding region:19-143(IPR013783)|mutation decreasing interaction strength:68-68,121-121|mutation decreasing interaction strength:68-68|mutation with no effect:121-121|mutation disrupting interaction strength:42-42,121-121|mutation disrupting interaction strength:42-42,68-68|mutation disrupting interaction strength:42-42,68-68,121-121 - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P46379 uniprotkb:O14931 intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4|ensembl:ENSP00000354368|ensembl:ENSP00000390966|ensembl:ENSP00000397894 intact:EBI-14989262|ensembl:ENSP00000416035|ensembl:ENSP00000416944|ensembl:ENSP00000342156|ensembl:ENSP00000372969|ensembl:ENSP00000389071|ensembl:ENSP00000390131|ensembl:ENSP00000398313|ensembl:ENSP00000405306|uniprotkb:B0S8F2|uniprotkb:B0S8F4|uniprotkb:B0S8F5|uniprotkb:O14930|uniprotkb:O14932|uniprotkb:O95667|uniprotkb:O95668|uniprotkb:O95669|uniprotkb:Q5ST89|uniprotkb:Q5ST90|uniprotkb:Q5ST91|uniprotkb:Q5ST92|uniprotkb:Q5STA3 psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym) psi-mi:nctr3_human(display_long)|uniprotkb:NCR3(gene name)|psi-mi:NCR3(display_short)|uniprotkb:1C7(gene name synonym)|uniprotkb:LY117(gene name synonym)|uniprotkb:Activating natural killer receptor p30(gene name synonym)|uniprotkb:Natural killer cell p30-related protein(gene name synonym) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Hartmann et al. (2012) pubmed:22807449|imex:IM-26120 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-15482006|imex:IM-26120-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|ensembl:ENSG00000096155(gene)|ensembl:ENSG00000229524(gene)|ensembl:ENSG00000233348(gene)|ensembl:ENST00000361076(transcript)|ensembl:ENST00000449450(transcript)|ensembl:ENST00000451932(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002429"(immune response-activating cell surface receptor signaling pathway)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070628"(proteasome binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0071818"(BAT3 complex)|go:"GO:1904294"(positive regulation of ERAD pathway)|go:"GO:1904378"(maintenance of unfolded protein involved in ERAD pathway)|go:"GO:1904379"(protein localization to cytosolic proteasome complex involved in ERAD pathway)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:6AU8|reactome:R-HSA-9609523|rcsb pdb:4X86 ensembl:ENSG00000204475(gene)|ensembl:ENSG00000206430(gene)|ensembl:ENSG00000223833(gene)|ensembl:ENSG00000225211(gene)|ensembl:ENSG00000236315(gene)|ensembl:ENST00000340027(transcript)|ensembl:ENST00000383477(transcript)|ensembl:ENST00000415123(transcript)|ensembl:ENST00000420556(transcript)|ensembl:ENST00000430599(transcript)|ensembl:ENST00000435674(transcript)|ensembl:ENST00000437517(transcript)|ensembl:ENST00000447248(transcript)|go:"GO:0002429"(immune response-activating cell surface receptor signaling pathway)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0008037"(cell recognition)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|interpro:IPR003599(Immunoglobulin subtype)|ensembl:ENSG00000236979(gene)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|ensembl:ENSG00000237103(gene)|ensembl:ENSG00000237808(gene)|interpro:IPR036179|interpro:IPR043226|rcsb pdb:3PV6|rcsb pdb:3NOI|rcsb pdb:6YJP|reactome:R-HSA-198933|refseq:NP_001138938.1|refseq:NP_001138939.1|refseq:NP_667341.1|refseq:XP_006715112.1|refseq:XP_011512761.1|dip:DIP-59939N - - - figure legend:"2H, 4C, 5C, supp fig 3B, (Table 1)"|comment:"A NKp30 mutant containing a length-matched glycine-serine (GS) linker instead of the stalk domain gave a Kd of 86nM-intermediate in value between the NKp30 Stalk and LBD construct."|comment:Kd values have been entered from Supp figure 3B - as the values differ slightly from those given in Table 1.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:48.0x10^-9(molar) 2017/07/10 2017/07/11 rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606 rogid:bS3R8rfddez5+tROQijf3FtslOU9606 rigid:S+R1Jkjs28DtSc+k4Nma9xYn3U0 false - mutation with no effect:42-42|mutation with no effect:42-42,68-68|mutation with no effect:42-42,68-68,121-121|mutation with no effect:68-68|mutation with no effect:121-121,68-68|mutation with no effect:121-121|mutation with no effect:42-42,121-121|fc-igg tag:c-c|sufficient binding region:19-143(IPR013783) 1 1 psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P46379 uniprotkb:O14931 intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4|ensembl:ENSP00000354368|ensembl:ENSP00000390966|ensembl:ENSP00000397894 intact:EBI-14989262|ensembl:ENSP00000416035|ensembl:ENSP00000416944|ensembl:ENSP00000342156|ensembl:ENSP00000372969|ensembl:ENSP00000389071|ensembl:ENSP00000390131|ensembl:ENSP00000398313|ensembl:ENSP00000405306|uniprotkb:B0S8F2|uniprotkb:B0S8F4|uniprotkb:B0S8F5|uniprotkb:O14930|uniprotkb:O14932|uniprotkb:O95667|uniprotkb:O95668|uniprotkb:O95669|uniprotkb:Q5ST89|uniprotkb:Q5ST90|uniprotkb:Q5ST91|uniprotkb:Q5ST92|uniprotkb:Q5STA3 psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym) psi-mi:nctr3_human(display_long)|uniprotkb:NCR3(gene name)|psi-mi:NCR3(display_short)|uniprotkb:1C7(gene name synonym)|uniprotkb:LY117(gene name synonym)|uniprotkb:Activating natural killer receptor p30(gene name synonym)|uniprotkb:Natural killer cell p30-related protein(gene name synonym) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Hartmann et al. (2012) pubmed:22807449|imex:IM-26120 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-15482033|imex:IM-26120-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|ensembl:ENSG00000096155(gene)|ensembl:ENSG00000229524(gene)|ensembl:ENSG00000233348(gene)|ensembl:ENST00000361076(transcript)|ensembl:ENST00000449450(transcript)|ensembl:ENST00000451932(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002429"(immune response-activating cell surface receptor signaling pathway)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070628"(proteasome binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0071818"(BAT3 complex)|go:"GO:1904294"(positive regulation of ERAD pathway)|go:"GO:1904378"(maintenance of unfolded protein involved in ERAD pathway)|go:"GO:1904379"(protein localization to cytosolic proteasome complex involved in ERAD pathway)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:6AU8|reactome:R-HSA-9609523|rcsb pdb:4X86 ensembl:ENSG00000204475(gene)|ensembl:ENSG00000206430(gene)|ensembl:ENSG00000223833(gene)|ensembl:ENSG00000225211(gene)|ensembl:ENSG00000236315(gene)|ensembl:ENST00000340027(transcript)|ensembl:ENST00000383477(transcript)|ensembl:ENST00000415123(transcript)|ensembl:ENST00000420556(transcript)|ensembl:ENST00000430599(transcript)|ensembl:ENST00000435674(transcript)|ensembl:ENST00000437517(transcript)|ensembl:ENST00000447248(transcript)|go:"GO:0002429"(immune response-activating cell surface receptor signaling pathway)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0008037"(cell recognition)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|interpro:IPR003599(Immunoglobulin subtype)|ensembl:ENSG00000236979(gene)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|ensembl:ENSG00000237103(gene)|ensembl:ENSG00000237808(gene)|interpro:IPR036179|interpro:IPR043226|rcsb pdb:3PV6|rcsb pdb:3NOI|rcsb pdb:6YJP|reactome:R-HSA-198933|refseq:NP_001138938.1|refseq:NP_001138939.1|refseq:NP_667341.1|refseq:XP_006715112.1|refseq:XP_011512761.1|dip:DIP-59939N - - - figure legend:2Hi, Supp 3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:126.0x10^-9(molar) 2017/07/10 2017/07/11 rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606 rogid:bS3R8rfddez5+tROQijf3FtslOU9606 rigid:S+R1Jkjs28DtSc+k4Nma9xYn3U0 false - sufficient binding region:19-128(IPR013783)|fc-igg tag:c-c 1 1 psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P46379 uniprotkb:O14931 intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4|ensembl:ENSP00000354368|ensembl:ENSP00000390966|ensembl:ENSP00000397894 intact:EBI-14989262|ensembl:ENSP00000416035|ensembl:ENSP00000416944|ensembl:ENSP00000342156|ensembl:ENSP00000372969|ensembl:ENSP00000389071|ensembl:ENSP00000390131|ensembl:ENSP00000398313|ensembl:ENSP00000405306|uniprotkb:B0S8F2|uniprotkb:B0S8F4|uniprotkb:B0S8F5|uniprotkb:O14930|uniprotkb:O14932|uniprotkb:O95667|uniprotkb:O95668|uniprotkb:O95669|uniprotkb:Q5ST89|uniprotkb:Q5ST90|uniprotkb:Q5ST91|uniprotkb:Q5ST92|uniprotkb:Q5STA3 psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym) psi-mi:nctr3_human(display_long)|uniprotkb:NCR3(gene name)|psi-mi:NCR3(display_short)|uniprotkb:1C7(gene name synonym)|uniprotkb:LY117(gene name synonym)|uniprotkb:Activating natural killer receptor p30(gene name synonym)|uniprotkb:Natural killer cell p30-related protein(gene name synonym) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Hartmann et al. (2012) pubmed:22807449|imex:IM-26120 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-15482465|imex:IM-26120-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|ensembl:ENSG00000096155(gene)|ensembl:ENSG00000229524(gene)|ensembl:ENSG00000233348(gene)|ensembl:ENST00000361076(transcript)|ensembl:ENST00000449450(transcript)|ensembl:ENST00000451932(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002429"(immune response-activating cell surface receptor signaling pathway)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070628"(proteasome binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0071818"(BAT3 complex)|go:"GO:1904294"(positive regulation of ERAD pathway)|go:"GO:1904378"(maintenance of unfolded protein involved in ERAD pathway)|go:"GO:1904379"(protein localization to cytosolic proteasome complex involved in ERAD pathway)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:6AU8|reactome:R-HSA-9609523|rcsb pdb:4X86 ensembl:ENSG00000204475(gene)|ensembl:ENSG00000206430(gene)|ensembl:ENSG00000223833(gene)|ensembl:ENSG00000225211(gene)|ensembl:ENSG00000236315(gene)|ensembl:ENST00000340027(transcript)|ensembl:ENST00000383477(transcript)|ensembl:ENST00000415123(transcript)|ensembl:ENST00000420556(transcript)|ensembl:ENST00000430599(transcript)|ensembl:ENST00000435674(transcript)|ensembl:ENST00000437517(transcript)|ensembl:ENST00000447248(transcript)|go:"GO:0002429"(immune response-activating cell surface receptor signaling pathway)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0008037"(cell recognition)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|interpro:IPR003599(Immunoglobulin subtype)|ensembl:ENSG00000236979(gene)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|ensembl:ENSG00000237103(gene)|ensembl:ENSG00000237808(gene)|interpro:IPR036179|interpro:IPR043226|rcsb pdb:3PV6|rcsb pdb:3NOI|rcsb pdb:6YJP|reactome:R-HSA-198933|refseq:NP_001138938.1|refseq:NP_001138939.1|refseq:NP_667341.1|refseq:XP_006715112.1|refseq:XP_011512761.1|dip:DIP-59939N - - - figure legend:5C, Supp 3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:79.0x10^-9(molar) 2017/07/10 2017/07/12 rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606 rogid:bS3R8rfddez5+tROQijf3FtslOU9606 rigid:S+R1Jkjs28DtSc+k4Nma9xYn3U0 false - sufficient binding region:19-140(IPR013783)|fc-igg tag:c-c 1 1 psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P46379 uniprotkb:O14931 intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4|ensembl:ENSP00000354368|ensembl:ENSP00000390966|ensembl:ENSP00000397894 intact:EBI-14989262|ensembl:ENSP00000416035|ensembl:ENSP00000416944|ensembl:ENSP00000342156|ensembl:ENSP00000372969|ensembl:ENSP00000389071|ensembl:ENSP00000390131|ensembl:ENSP00000398313|ensembl:ENSP00000405306|uniprotkb:B0S8F2|uniprotkb:B0S8F4|uniprotkb:B0S8F5|uniprotkb:O14930|uniprotkb:O14932|uniprotkb:O95667|uniprotkb:O95668|uniprotkb:O95669|uniprotkb:Q5ST89|uniprotkb:Q5ST90|uniprotkb:Q5ST91|uniprotkb:Q5ST92|uniprotkb:Q5STA3 psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym) psi-mi:nctr3_human(display_long)|uniprotkb:NCR3(gene name)|psi-mi:NCR3(display_short)|uniprotkb:1C7(gene name synonym)|uniprotkb:LY117(gene name synonym)|uniprotkb:Activating natural killer receptor p30(gene name synonym)|uniprotkb:Natural killer cell p30-related protein(gene name synonym) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Hartmann et al. (2012) pubmed:22807449|imex:IM-26120 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-15482483|imex:IM-26120-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|ensembl:ENSG00000096155(gene)|ensembl:ENSG00000229524(gene)|ensembl:ENSG00000233348(gene)|ensembl:ENST00000361076(transcript)|ensembl:ENST00000449450(transcript)|ensembl:ENST00000451932(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002429"(immune response-activating cell surface receptor signaling pathway)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070628"(proteasome binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0071818"(BAT3 complex)|go:"GO:1904294"(positive regulation of ERAD pathway)|go:"GO:1904378"(maintenance of unfolded protein involved in ERAD pathway)|go:"GO:1904379"(protein localization to cytosolic proteasome complex involved in ERAD pathway)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:6AU8|reactome:R-HSA-9609523|rcsb pdb:4X86 ensembl:ENSG00000204475(gene)|ensembl:ENSG00000206430(gene)|ensembl:ENSG00000223833(gene)|ensembl:ENSG00000225211(gene)|ensembl:ENSG00000236315(gene)|ensembl:ENST00000340027(transcript)|ensembl:ENST00000383477(transcript)|ensembl:ENST00000415123(transcript)|ensembl:ENST00000420556(transcript)|ensembl:ENST00000430599(transcript)|ensembl:ENST00000435674(transcript)|ensembl:ENST00000437517(transcript)|ensembl:ENST00000447248(transcript)|go:"GO:0002429"(immune response-activating cell surface receptor signaling pathway)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0008037"(cell recognition)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|interpro:IPR003599(Immunoglobulin subtype)|ensembl:ENSG00000236979(gene)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|ensembl:ENSG00000237103(gene)|ensembl:ENSG00000237808(gene)|interpro:IPR036179|interpro:IPR043226|rcsb pdb:3PV6|rcsb pdb:3NOI|rcsb pdb:6YJP|reactome:R-HSA-198933|refseq:NP_001138938.1|refseq:NP_001138939.1|refseq:NP_667341.1|refseq:XP_006715112.1|refseq:XP_011512761.1|dip:DIP-59939N - - - figure legend:5Ci, Supp 3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:62.0x10^-9(molar) 2017/07/10 2017/07/12 rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606 rogid:bS3R8rfddez5+tROQijf3FtslOU9606 rigid:S+R1Jkjs28DtSc+k4Nma9xYn3U0 false - sufficient binding region:19-136(IPR013783)|fc-igg tag:c-c 1 1 psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P46379 uniprotkb:O14931 intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4|ensembl:ENSP00000354368|ensembl:ENSP00000390966|ensembl:ENSP00000397894 intact:EBI-14989262|ensembl:ENSP00000416035|ensembl:ENSP00000416944|ensembl:ENSP00000342156|ensembl:ENSP00000372969|ensembl:ENSP00000389071|ensembl:ENSP00000390131|ensembl:ENSP00000398313|ensembl:ENSP00000405306|uniprotkb:B0S8F2|uniprotkb:B0S8F4|uniprotkb:B0S8F5|uniprotkb:O14930|uniprotkb:O14932|uniprotkb:O95667|uniprotkb:O95668|uniprotkb:O95669|uniprotkb:Q5ST89|uniprotkb:Q5ST90|uniprotkb:Q5ST91|uniprotkb:Q5ST92|uniprotkb:Q5STA3 psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym) psi-mi:nctr3_human(display_long)|uniprotkb:NCR3(gene name)|psi-mi:NCR3(display_short)|uniprotkb:1C7(gene name synonym)|uniprotkb:LY117(gene name synonym)|uniprotkb:Activating natural killer receptor p30(gene name synonym)|uniprotkb:Natural killer cell p30-related protein(gene name synonym) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Hartmann et al. (2012) pubmed:22807449|imex:IM-26120 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-15482493|imex:IM-26120-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|ensembl:ENSG00000096155(gene)|ensembl:ENSG00000229524(gene)|ensembl:ENSG00000233348(gene)|ensembl:ENST00000361076(transcript)|ensembl:ENST00000449450(transcript)|ensembl:ENST00000451932(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002429"(immune response-activating cell surface receptor signaling pathway)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070628"(proteasome binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0071818"(BAT3 complex)|go:"GO:1904294"(positive regulation of ERAD pathway)|go:"GO:1904378"(maintenance of unfolded protein involved in ERAD pathway)|go:"GO:1904379"(protein localization to cytosolic proteasome complex involved in ERAD pathway)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:6AU8|reactome:R-HSA-9609523|rcsb pdb:4X86 ensembl:ENSG00000204475(gene)|ensembl:ENSG00000206430(gene)|ensembl:ENSG00000223833(gene)|ensembl:ENSG00000225211(gene)|ensembl:ENSG00000236315(gene)|ensembl:ENST00000340027(transcript)|ensembl:ENST00000383477(transcript)|ensembl:ENST00000415123(transcript)|ensembl:ENST00000420556(transcript)|ensembl:ENST00000430599(transcript)|ensembl:ENST00000435674(transcript)|ensembl:ENST00000437517(transcript)|ensembl:ENST00000447248(transcript)|go:"GO:0002429"(immune response-activating cell surface receptor signaling pathway)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0008037"(cell recognition)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|interpro:IPR003599(Immunoglobulin subtype)|ensembl:ENSG00000236979(gene)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|ensembl:ENSG00000237103(gene)|ensembl:ENSG00000237808(gene)|interpro:IPR036179|interpro:IPR043226|rcsb pdb:3PV6|rcsb pdb:3NOI|rcsb pdb:6YJP|reactome:R-HSA-198933|refseq:NP_001138938.1|refseq:NP_001138939.1|refseq:NP_667341.1|refseq:XP_006715112.1|refseq:XP_011512761.1|dip:DIP-59939N - - - figure legend:5Cii|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:93.0x10^-9(molar) 2017/07/10 2017/07/12 rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606 rogid:bS3R8rfddez5+tROQijf3FtslOU9606 rigid:S+R1Jkjs28DtSc+k4Nma9xYn3U0 false - sufficient binding region:19-132(IPR013783)|fc-igg tag:c-c 1 1 psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q68D85 uniprotkb:O14931 intact:EBI-14061804|uniprotkb:Q7Z3M6|ensembl:ENSP00000341637|ensembl:ENSP00000434394 intact:EBI-14989262|ensembl:ENSP00000416035|ensembl:ENSP00000416944|ensembl:ENSP00000342156|ensembl:ENSP00000372969|ensembl:ENSP00000389071|ensembl:ENSP00000390131|ensembl:ENSP00000398313|ensembl:ENSP00000405306|uniprotkb:B0S8F2|uniprotkb:B0S8F4|uniprotkb:B0S8F5|uniprotkb:O14930|uniprotkb:O14932|uniprotkb:O95667|uniprotkb:O95668|uniprotkb:O95669|uniprotkb:Q5ST89|uniprotkb:Q5ST90|uniprotkb:Q5ST91|uniprotkb:Q5ST92|uniprotkb:Q5STA3 psi-mi:nr3l1_human(display_long)|uniprotkb:NCR3LG1(gene name)|psi-mi:NCR3LG1(display_short)|uniprotkb:B7 homolog 6(gene name synonym)|uniprotkb:B7H6(gene name synonym) psi-mi:nctr3_human(display_long)|uniprotkb:NCR3(gene name)|psi-mi:NCR3(display_short)|uniprotkb:1C7(gene name synonym)|uniprotkb:LY117(gene name synonym)|uniprotkb:Activating natural killer receptor p30(gene name synonym)|uniprotkb:Natural killer cell p30-related protein(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Hartmann et al. (2012) pubmed:22807449|imex:IM-26120 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-15482051|imex:IM-26120-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001189368.1|ensembl:ENSG00000188211(gene)|ensembl:ENST00000338965(transcript)|ensembl:ENST00000530403(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR036946|rcsb pdb:3PV6|rcsb pdb:3PV7|rcsb pdb:4ZSO|rcsb pdb:6YJP|reactome:R-HSA-198933|dip:DIP-59940N ensembl:ENSG00000204475(gene)|ensembl:ENSG00000206430(gene)|ensembl:ENSG00000223833(gene)|ensembl:ENSG00000225211(gene)|ensembl:ENSG00000236315(gene)|ensembl:ENST00000340027(transcript)|ensembl:ENST00000383477(transcript)|ensembl:ENST00000415123(transcript)|ensembl:ENST00000420556(transcript)|ensembl:ENST00000430599(transcript)|ensembl:ENST00000435674(transcript)|ensembl:ENST00000437517(transcript)|ensembl:ENST00000447248(transcript)|go:"GO:0002429"(immune response-activating cell surface receptor signaling pathway)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0008037"(cell recognition)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|interpro:IPR003599(Immunoglobulin subtype)|ensembl:ENSG00000236979(gene)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|ensembl:ENSG00000237103(gene)|ensembl:ENSG00000237808(gene)|interpro:IPR036179|interpro:IPR043226|rcsb pdb:3PV6|rcsb pdb:3NOI|rcsb pdb:6YJP|reactome:R-HSA-198933|refseq:NP_001138938.1|refseq:NP_001138939.1|refseq:NP_667341.1|refseq:XP_006715112.1|refseq:XP_011512761.1|dip:DIP-59939N - - - figure legend:3 A/C, 3 G-M, Table 2|kinetics:"A NKp30 mutant containing a length-matched glycine-serine (GS) linker instead of the stalk domain gave a Kd of 114nM."|caution:"For the N68Q,N121Q double mutant different Kd values are given on figure 3 (4,727) and Table 2 (3,323); an average value has been entered here."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:76.0x10^-9(molar) 2017/07/10 2017/07/11 rogid:zxyF+bJz/qWtsilosYWPqwnDUw89606 rogid:bS3R8rfddez5+tROQijf3FtslOU9606 rigid:RGs60g1CS7VjnF4PJeDm9zXbysI false sufficient binding region:25..25-262..262|fc-igg tag:c-c mutation disrupting interaction strength:42-42|fc-igg tag:c-c|sufficient binding region:19-143(IPR013783)|mutation decreasing interaction strength:68-68,121-121|mutation decreasing interaction strength:68-68|mutation with no effect:121-121|mutation disrupting interaction strength:42-42,121-121|mutation disrupting interaction strength:42-42,68-68|mutation disrupting interaction strength:42-42,68-68,121-121 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q68D85 uniprotkb:O14931 intact:EBI-14061804|uniprotkb:Q7Z3M6|ensembl:ENSP00000341637|ensembl:ENSP00000434394 intact:EBI-14989262|ensembl:ENSP00000416035|ensembl:ENSP00000416944|ensembl:ENSP00000342156|ensembl:ENSP00000372969|ensembl:ENSP00000389071|ensembl:ENSP00000390131|ensembl:ENSP00000398313|ensembl:ENSP00000405306|uniprotkb:B0S8F2|uniprotkb:B0S8F4|uniprotkb:B0S8F5|uniprotkb:O14930|uniprotkb:O14932|uniprotkb:O95667|uniprotkb:O95668|uniprotkb:O95669|uniprotkb:Q5ST89|uniprotkb:Q5ST90|uniprotkb:Q5ST91|uniprotkb:Q5ST92|uniprotkb:Q5STA3 psi-mi:nr3l1_human(display_long)|uniprotkb:NCR3LG1(gene name)|psi-mi:NCR3LG1(display_short)|uniprotkb:B7 homolog 6(gene name synonym)|uniprotkb:B7H6(gene name synonym) psi-mi:nctr3_human(display_long)|uniprotkb:NCR3(gene name)|psi-mi:NCR3(display_short)|uniprotkb:1C7(gene name synonym)|uniprotkb:LY117(gene name synonym)|uniprotkb:Activating natural killer receptor p30(gene name synonym)|uniprotkb:Natural killer cell p30-related protein(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Hartmann et al. (2012) pubmed:22807449|imex:IM-26120 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-15482065|imex:IM-26120-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001189368.1|ensembl:ENSG00000188211(gene)|ensembl:ENST00000338965(transcript)|ensembl:ENST00000530403(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR036946|rcsb pdb:3PV6|rcsb pdb:3PV7|rcsb pdb:4ZSO|rcsb pdb:6YJP|reactome:R-HSA-198933|dip:DIP-59940N ensembl:ENSG00000204475(gene)|ensembl:ENSG00000206430(gene)|ensembl:ENSG00000223833(gene)|ensembl:ENSG00000225211(gene)|ensembl:ENSG00000236315(gene)|ensembl:ENST00000340027(transcript)|ensembl:ENST00000383477(transcript)|ensembl:ENST00000415123(transcript)|ensembl:ENST00000420556(transcript)|ensembl:ENST00000430599(transcript)|ensembl:ENST00000435674(transcript)|ensembl:ENST00000437517(transcript)|ensembl:ENST00000447248(transcript)|go:"GO:0002429"(immune response-activating cell surface receptor signaling pathway)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0008037"(cell recognition)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|interpro:IPR003599(Immunoglobulin subtype)|ensembl:ENSG00000236979(gene)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|ensembl:ENSG00000237103(gene)|ensembl:ENSG00000237808(gene)|interpro:IPR036179|interpro:IPR043226|rcsb pdb:3PV6|rcsb pdb:3NOI|rcsb pdb:6YJP|reactome:R-HSA-198933|refseq:NP_001138938.1|refseq:NP_001138939.1|refseq:NP_667341.1|refseq:XP_006715112.1|refseq:XP_011512761.1|dip:DIP-59939N - - - figure legend:3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:149.0x10^-9(molar) 2017/07/10 2017/07/11 rogid:zxyF+bJz/qWtsilosYWPqwnDUw89606 rogid:bS3R8rfddez5+tROQijf3FtslOU9606 rigid:RGs60g1CS7VjnF4PJeDm9zXbysI false sufficient binding region:25..25-262..262|fc-igg tag:c-c fc-igg tag:c-c|sufficient binding region:19-128(IPR013783) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q68D85 uniprotkb:O14931 intact:EBI-14061804|uniprotkb:Q7Z3M6|ensembl:ENSP00000341637|ensembl:ENSP00000434394 intact:EBI-14989262|ensembl:ENSP00000416035|ensembl:ENSP00000416944|ensembl:ENSP00000342156|ensembl:ENSP00000372969|ensembl:ENSP00000389071|ensembl:ENSP00000390131|ensembl:ENSP00000398313|ensembl:ENSP00000405306|uniprotkb:B0S8F2|uniprotkb:B0S8F4|uniprotkb:B0S8F5|uniprotkb:O14930|uniprotkb:O14932|uniprotkb:O95667|uniprotkb:O95668|uniprotkb:O95669|uniprotkb:Q5ST89|uniprotkb:Q5ST90|uniprotkb:Q5ST91|uniprotkb:Q5ST92|uniprotkb:Q5STA3 psi-mi:nr3l1_human(display_long)|uniprotkb:NCR3LG1(gene name)|psi-mi:NCR3LG1(display_short)|uniprotkb:B7 homolog 6(gene name synonym)|uniprotkb:B7H6(gene name synonym) psi-mi:nctr3_human(display_long)|uniprotkb:NCR3(gene name)|psi-mi:NCR3(display_short)|uniprotkb:1C7(gene name synonym)|uniprotkb:LY117(gene name synonym)|uniprotkb:Activating natural killer receptor p30(gene name synonym)|uniprotkb:Natural killer cell p30-related protein(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Hartmann et al. (2012) pubmed:22807449|imex:IM-26120 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-15482081|imex:IM-26120-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001189368.1|ensembl:ENSG00000188211(gene)|ensembl:ENST00000338965(transcript)|ensembl:ENST00000530403(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR036946|rcsb pdb:3PV6|rcsb pdb:3PV7|rcsb pdb:4ZSO|rcsb pdb:6YJP|reactome:R-HSA-198933|dip:DIP-59940N ensembl:ENSG00000204475(gene)|ensembl:ENSG00000206430(gene)|ensembl:ENSG00000223833(gene)|ensembl:ENSG00000225211(gene)|ensembl:ENSG00000236315(gene)|ensembl:ENST00000340027(transcript)|ensembl:ENST00000383477(transcript)|ensembl:ENST00000415123(transcript)|ensembl:ENST00000420556(transcript)|ensembl:ENST00000430599(transcript)|ensembl:ENST00000435674(transcript)|ensembl:ENST00000437517(transcript)|ensembl:ENST00000447248(transcript)|go:"GO:0002429"(immune response-activating cell surface receptor signaling pathway)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0008037"(cell recognition)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|interpro:IPR003599(Immunoglobulin subtype)|ensembl:ENSG00000236979(gene)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|ensembl:ENSG00000237103(gene)|ensembl:ENSG00000237808(gene)|interpro:IPR036179|interpro:IPR043226|rcsb pdb:3PV6|rcsb pdb:3NOI|rcsb pdb:6YJP|reactome:R-HSA-198933|refseq:NP_001138938.1|refseq:NP_001138939.1|refseq:NP_667341.1|refseq:XP_006715112.1|refseq:XP_011512761.1|dip:DIP-59939N - - - figure legend:3D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:132.0x10^-9(molar) 2017/07/10 2017/07/11 rogid:zxyF+bJz/qWtsilosYWPqwnDUw89606 rogid:bS3R8rfddez5+tROQijf3FtslOU9606 rigid:RGs60g1CS7VjnF4PJeDm9zXbysI false sufficient binding region:25..25-262..262|fc-igg tag:c-c fc-igg tag:c-c|sufficient binding region:19-140(IPR013783) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q68D85 uniprotkb:O14931 intact:EBI-14061804|uniprotkb:Q7Z3M6|ensembl:ENSP00000341637|ensembl:ENSP00000434394 intact:EBI-14989262|ensembl:ENSP00000416035|ensembl:ENSP00000416944|ensembl:ENSP00000342156|ensembl:ENSP00000372969|ensembl:ENSP00000389071|ensembl:ENSP00000390131|ensembl:ENSP00000398313|ensembl:ENSP00000405306|uniprotkb:B0S8F2|uniprotkb:B0S8F4|uniprotkb:B0S8F5|uniprotkb:O14930|uniprotkb:O14932|uniprotkb:O95667|uniprotkb:O95668|uniprotkb:O95669|uniprotkb:Q5ST89|uniprotkb:Q5ST90|uniprotkb:Q5ST91|uniprotkb:Q5ST92|uniprotkb:Q5STA3 psi-mi:nr3l1_human(display_long)|uniprotkb:NCR3LG1(gene name)|psi-mi:NCR3LG1(display_short)|uniprotkb:B7 homolog 6(gene name synonym)|uniprotkb:B7H6(gene name synonym) psi-mi:nctr3_human(display_long)|uniprotkb:NCR3(gene name)|psi-mi:NCR3(display_short)|uniprotkb:1C7(gene name synonym)|uniprotkb:LY117(gene name synonym)|uniprotkb:Activating natural killer receptor p30(gene name synonym)|uniprotkb:Natural killer cell p30-related protein(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Hartmann et al. (2012) pubmed:22807449|imex:IM-26120 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-15482097|imex:IM-26120-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001189368.1|ensembl:ENSG00000188211(gene)|ensembl:ENST00000338965(transcript)|ensembl:ENST00000530403(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR036946|rcsb pdb:3PV6|rcsb pdb:3PV7|rcsb pdb:4ZSO|rcsb pdb:6YJP|reactome:R-HSA-198933|dip:DIP-59940N ensembl:ENSG00000204475(gene)|ensembl:ENSG00000206430(gene)|ensembl:ENSG00000223833(gene)|ensembl:ENSG00000225211(gene)|ensembl:ENSG00000236315(gene)|ensembl:ENST00000340027(transcript)|ensembl:ENST00000383477(transcript)|ensembl:ENST00000415123(transcript)|ensembl:ENST00000420556(transcript)|ensembl:ENST00000430599(transcript)|ensembl:ENST00000435674(transcript)|ensembl:ENST00000437517(transcript)|ensembl:ENST00000447248(transcript)|go:"GO:0002429"(immune response-activating cell surface receptor signaling pathway)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0008037"(cell recognition)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|interpro:IPR003599(Immunoglobulin subtype)|ensembl:ENSG00000236979(gene)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|ensembl:ENSG00000237103(gene)|ensembl:ENSG00000237808(gene)|interpro:IPR036179|interpro:IPR043226|rcsb pdb:3PV6|rcsb pdb:3NOI|rcsb pdb:6YJP|reactome:R-HSA-198933|refseq:NP_001138938.1|refseq:NP_001138939.1|refseq:NP_667341.1|refseq:XP_006715112.1|refseq:XP_011512761.1|dip:DIP-59939N - - - figure legend:3E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:133.0x10^-9(molar) 2017/07/10 2017/07/11 rogid:zxyF+bJz/qWtsilosYWPqwnDUw89606 rogid:bS3R8rfddez5+tROQijf3FtslOU9606 rigid:RGs60g1CS7VjnF4PJeDm9zXbysI false sufficient binding region:25..25-262..262|fc-igg tag:c-c fc-igg tag:c-c|sufficient binding region:19-136(IPR013783) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q68D85 uniprotkb:O14931 intact:EBI-14061804|uniprotkb:Q7Z3M6|ensembl:ENSP00000341637|ensembl:ENSP00000434394 intact:EBI-14989262|ensembl:ENSP00000416035|ensembl:ENSP00000416944|ensembl:ENSP00000342156|ensembl:ENSP00000372969|ensembl:ENSP00000389071|ensembl:ENSP00000390131|ensembl:ENSP00000398313|ensembl:ENSP00000405306|uniprotkb:B0S8F2|uniprotkb:B0S8F4|uniprotkb:B0S8F5|uniprotkb:O14930|uniprotkb:O14932|uniprotkb:O95667|uniprotkb:O95668|uniprotkb:O95669|uniprotkb:Q5ST89|uniprotkb:Q5ST90|uniprotkb:Q5ST91|uniprotkb:Q5ST92|uniprotkb:Q5STA3 psi-mi:nr3l1_human(display_long)|uniprotkb:NCR3LG1(gene name)|psi-mi:NCR3LG1(display_short)|uniprotkb:B7 homolog 6(gene name synonym)|uniprotkb:B7H6(gene name synonym) psi-mi:nctr3_human(display_long)|uniprotkb:NCR3(gene name)|psi-mi:NCR3(display_short)|uniprotkb:1C7(gene name synonym)|uniprotkb:LY117(gene name synonym)|uniprotkb:Activating natural killer receptor p30(gene name synonym)|uniprotkb:Natural killer cell p30-related protein(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Hartmann et al. (2012) pubmed:22807449|imex:IM-26120 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-15482111|imex:IM-26120-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001189368.1|ensembl:ENSG00000188211(gene)|ensembl:ENST00000338965(transcript)|ensembl:ENST00000530403(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR036946|rcsb pdb:3PV6|rcsb pdb:3PV7|rcsb pdb:4ZSO|rcsb pdb:6YJP|reactome:R-HSA-198933|dip:DIP-59940N ensembl:ENSG00000204475(gene)|ensembl:ENSG00000206430(gene)|ensembl:ENSG00000223833(gene)|ensembl:ENSG00000225211(gene)|ensembl:ENSG00000236315(gene)|ensembl:ENST00000340027(transcript)|ensembl:ENST00000383477(transcript)|ensembl:ENST00000415123(transcript)|ensembl:ENST00000420556(transcript)|ensembl:ENST00000430599(transcript)|ensembl:ENST00000435674(transcript)|ensembl:ENST00000437517(transcript)|ensembl:ENST00000447248(transcript)|go:"GO:0002429"(immune response-activating cell surface receptor signaling pathway)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0008037"(cell recognition)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|interpro:IPR003599(Immunoglobulin subtype)|ensembl:ENSG00000236979(gene)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|ensembl:ENSG00000237103(gene)|ensembl:ENSG00000237808(gene)|interpro:IPR036179|interpro:IPR043226|rcsb pdb:3PV6|rcsb pdb:3NOI|rcsb pdb:6YJP|reactome:R-HSA-198933|refseq:NP_001138938.1|refseq:NP_001138939.1|refseq:NP_667341.1|refseq:XP_006715112.1|refseq:XP_011512761.1|dip:DIP-59939N - - - figure legend:3F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:132.0x10^-9(molar) 2017/07/10 2017/07/11 rogid:zxyF+bJz/qWtsilosYWPqwnDUw89606 rogid:bS3R8rfddez5+tROQijf3FtslOU9606 rigid:RGs60g1CS7VjnF4PJeDm9zXbysI false sufficient binding region:25..25-262..262|fc-igg tag:c-c fc-igg tag:c-c|sufficient binding region:19-132(IPR013783) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)