#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q99NC0 uniprotkb:Q62296-1 intact:EBI-15985690|ensembl:ENSMUSP00000033465|ensembl:ENSMUSP00000110393|ensembl:ENSMUSP00000110394|uniprotkb:A2AFJ9 intact:EBI-15985676|ensembl:ENSMUSP00000006311 psi-mi:vgll1_mouse(display_long)|uniprotkb:Vgll1(gene name)|psi-mi:Vgll1(display_short)|uniprotkb:Vestigial-related factor(gene name synonym) psi-mi:q62296-1(display_long)|uniprotkb:Tead4(gene name)|psi-mi:Tead4(display_short)|uniprotkb:Tcf13r1(gene name synonym)|uniprotkb:Tef3(gene name synonym)|uniprotkb:Tefr1(gene name synonym)|uniprotkb:TEFR1A(isoform synonym)|uniprotkb:ETFR-2A(isoform synonym)|uniprotkb:ETF-related factor 2(gene name synonym)|uniprotkb:TEA domain family member 4(gene name synonym)|uniprotkb:TEF-1-related factor 1(gene name synonym)|uniprotkb:TEF-1-related factor FR-19(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pobbati et al. (2012) pubmed:22632831|doi:10.1016/j.str.2012.04.004|imex:IM-18021 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15985714|imex:IM-18021-1|dip:DIP-189622E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031131(gene)|ensembl:ENSMUST00000033465(transcript)|ensembl:ENSMUST00000114745(transcript)|ensembl:ENSMUST00000114746(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|interpro:IPR011520(Vestigial/tondu)|rcsb pdb:5Z2Q|refseq:NP_001300692.1|refseq:NP_573514.1|dip:DIP-59848N intact:EBI-9253444(isoform-parent)|ensembl:ENSMUSG00000030353(gene)|ensembl:ENSMUST00000006311(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:2e9f+/WDpoxY0z0XQCSuU6vOL8M10090 rogid:AsL1gpxJ7abeFVwJyF1xUkc8Q2c10090 rigid:SInkJlyMWQLD95YRq+Qhr735Ts4 false mutation decreasing interaction strength:45-45,44-44|flag tag:n-n ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P46937 uniprotkb:Q62296-1 intact:EBI-1044059|uniprotkb:Q7Z574|uniprotkb:Q8IUY9|ensembl:ENSP00000282441|intact:EBI-28992622|uniprotkb:B7ZA01|uniprotkb:E3WEB5|uniprotkb:E3WEB6|uniprotkb:E9PRV2|uniprotkb:F5H202|uniprotkb:K0KQ18|uniprotkb:K0KYZ8|uniprotkb:K0L195|uniprotkb:K0L1G3|uniprotkb:B4DTY1 intact:EBI-15985676|ensembl:ENSMUSP00000006311 psi-mi:yap1_human(display_long)|uniprotkb:YAP1(gene name)|psi-mi:YAP1(display_short)|uniprotkb:YAP65(gene name synonym)|uniprotkb:Protein yorkie homolog(gene name synonym)|uniprotkb:Yes-associated protein YAP65 homolog(gene name synonym) psi-mi:q62296-1(display_long)|uniprotkb:Tead4(gene name)|psi-mi:Tead4(display_short)|uniprotkb:Tcf13r1(gene name synonym)|uniprotkb:Tef3(gene name synonym)|uniprotkb:Tefr1(gene name synonym)|uniprotkb:TEFR1A(isoform synonym)|uniprotkb:ETFR-2A(isoform synonym)|uniprotkb:ETF-related factor 2(gene name synonym)|uniprotkb:TEA domain family member 4(gene name synonym)|uniprotkb:TEF-1-related factor 1(gene name synonym)|uniprotkb:TEF-1-related factor FR-19(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pobbati et al. (2012) pubmed:22632831|doi:10.1016/j.str.2012.04.004|imex:IM-18021 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15985741|imex:IM-18021-2|dip:DIP-189623E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001269026.1|ensembl:ENST00000282441(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001674"(female germ cell nucleus)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003015"(heart process)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|ensembl:ENSG00000137693(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030857"(negative regulation of epithelial cell differentiation)|go:"GO:0030903"(notochord development)|go:"GO:0032570"(response to progesterone)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035329"(hippo signaling)|go:"GO:0042060"(wound healing)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048368"(lateral mesoderm development)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050847"(progesterone receptor signaling pathway)|refseq:NP_001123617.1|refseq:NP_001181973.1|refseq:NP_001181974.1|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140552"(TEAD-YAP complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:1904036"(negative regulation of epithelial cell apoptotic process)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|mint:P46937|rcsb pdb:1JMQ|rcsb pdb:1K5R|rcsb pdb:1K9Q|rcsb pdb:1K9R|rcsb pdb:2LAW|rcsb pdb:2LAX|rcsb pdb:2LAY|rcsb pdb:2LTV|rcsb pdb:2LTW|rcsb pdb:3KYS|rcsb pdb:3MHR|rcsb pdb:4RE1|rcsb pdb:4REX|rcsb pdb:5OAQ|rcsb pdb:5YDX|rcsb pdb:5YDY|rcsb pdb:6G6X|rcsb pdb:6G8I|rcsb pdb:6G8J|rcsb pdb:6G8K|rcsb pdb:6G8L|rcsb pdb:6G8P|rcsb pdb:6G8Q|rcsb pdb:6GE3|rcsb pdb:6GE4|rcsb pdb:6GE5|rcsb pdb:6GE6|rcsb pdb:6GEC|rcsb pdb:6GEE|rcsb pdb:6GEG|go:"GO:0070064"(proline-rich region binding)|rcsb pdb:6GEI|rcsb pdb:6GEK|rcsb pdb:6HIK|rcsb pdb:6HIL|rcsb pdb:6Q2X|reactome:R-HSA-1251985|reactome:R-HSA-2028269|reactome:R-HSA-2032785|reactome:R-HSA-8939236|reactome:R-HSA-8940973|reactome:R-HSA-8951671|reactome:R-HSA-9619665|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060242"(contact inhibition)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0060487"(lung epithelial cell differentiation)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0061026"(cardiac muscle tissue regeneration)|go:"GO:0065003"(protein-containing complex assembly)|ensembl:ENSP00000282441|ensembl:ENST00000345877|ensembl:ENSP00000331023|ensembl:ENST00000524575|ensembl:ENSP00000435602|ensembl:ENST00000526343|refseq:NP_001269027.1|refseq:NP_001269028.1|refseq:NP_001269029.1|refseq:NP_001269030.1|ensembl:ENSP00000434134|ensembl:ENST00000531439|ensembl:ENSP00000431574|ensembl:ENSP00000487519|ensembl:ENST00000537274|ensembl:ENSP00000445635|ensembl:ENST00000615667|ensembl:ENSP00000478927|ensembl:ENST00000629586|dip:DIP-40839N intact:EBI-9253444(isoform-parent)|ensembl:ENSMUSG00000030353(gene)|ensembl:ENSMUST00000006311(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:bDNDhtCh5Qjdk1+PNM8Qb/340A09606 rogid:AsL1gpxJ7abeFVwJyF1xUkc8Q2c10090 rigid:UGK1xWCKBHt13r6nAwWw3eFswXs false - ha tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q99NC0 uniprotkb:Q62296-1 intact:EBI-15985690|ensembl:ENSMUSP00000033465|ensembl:ENSMUSP00000110393|ensembl:ENSMUSP00000110394|uniprotkb:A2AFJ9 intact:EBI-15985676|ensembl:ENSMUSP00000006311 psi-mi:vgll1_mouse(display_long)|uniprotkb:Vgll1(gene name)|psi-mi:Vgll1(display_short)|uniprotkb:Vestigial-related factor(gene name synonym) psi-mi:q62296-1(display_long)|uniprotkb:Tead4(gene name)|psi-mi:Tead4(display_short)|uniprotkb:Tcf13r1(gene name synonym)|uniprotkb:Tef3(gene name synonym)|uniprotkb:Tefr1(gene name synonym)|uniprotkb:TEFR1A(isoform synonym)|uniprotkb:ETFR-2A(isoform synonym)|uniprotkb:ETF-related factor 2(gene name synonym)|uniprotkb:TEA domain family member 4(gene name synonym)|uniprotkb:TEF-1-related factor 1(gene name synonym)|uniprotkb:TEF-1-related factor FR-19(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Pobbati et al. (2012) pubmed:22632831|doi:10.1016/j.str.2012.04.004|imex:IM-18021 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15985762|imex:IM-18021-3|dip:DIP-189622E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031131(gene)|ensembl:ENSMUST00000033465(transcript)|ensembl:ENSMUST00000114745(transcript)|ensembl:ENSMUST00000114746(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|interpro:IPR011520(Vestigial/tondu)|rcsb pdb:5Z2Q|refseq:NP_001300692.1|refseq:NP_573514.1|dip:DIP-59848N intact:EBI-9253444(isoform-parent)|ensembl:ENSMUSG00000030353(gene)|ensembl:ENSMUST00000006311(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:2e9f+/WDpoxY0z0XQCSuU6vOL8M10090 rogid:AsL1gpxJ7abeFVwJyF1xUkc8Q2c10090 rigid:SInkJlyMWQLD95YRq+Qhr735Ts4 false sufficient binding region:20-56 sufficient binding region:210-427 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99NC0 uniprotkb:Q62296-1 intact:EBI-15985690|ensembl:ENSMUSP00000033465|ensembl:ENSMUSP00000110393|ensembl:ENSMUSP00000110394|uniprotkb:A2AFJ9 intact:EBI-15985676|ensembl:ENSMUSP00000006311 psi-mi:vgll1_mouse(display_long)|uniprotkb:Vgll1(gene name)|psi-mi:Vgll1(display_short)|uniprotkb:Vestigial-related factor(gene name synonym) psi-mi:q62296-1(display_long)|uniprotkb:Tead4(gene name)|psi-mi:Tead4(display_short)|uniprotkb:Tcf13r1(gene name synonym)|uniprotkb:Tef3(gene name synonym)|uniprotkb:Tefr1(gene name synonym)|uniprotkb:TEFR1A(isoform synonym)|uniprotkb:ETFR-2A(isoform synonym)|uniprotkb:ETF-related factor 2(gene name synonym)|uniprotkb:TEA domain family member 4(gene name synonym)|uniprotkb:TEF-1-related factor 1(gene name synonym)|uniprotkb:TEF-1-related factor FR-19(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Pobbati et al. (2012) pubmed:22632831|doi:10.1016/j.str.2012.04.004|imex:IM-18021 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15985784|imex:IM-18021-4|dip:DIP-189622E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031131(gene)|ensembl:ENSMUST00000033465(transcript)|ensembl:ENSMUST00000114745(transcript)|ensembl:ENSMUST00000114746(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|interpro:IPR011520(Vestigial/tondu)|rcsb pdb:5Z2Q|refseq:NP_001300692.1|refseq:NP_573514.1|dip:DIP-59848N intact:EBI-9253444(isoform-parent)|ensembl:ENSMUSG00000030353(gene)|ensembl:ENSMUST00000006311(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:2e9f+/WDpoxY0z0XQCSuU6vOL8M10090 rogid:AsL1gpxJ7abeFVwJyF1xUkc8Q2c10090 rigid:SInkJlyMWQLD95YRq+Qhr735Ts4 false sufficient binding region:20-56 sufficient binding region:210-427 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99NC0 uniprotkb:Q62296-1 intact:EBI-15985690|ensembl:ENSMUSP00000033465|ensembl:ENSMUSP00000110393|ensembl:ENSMUSP00000110394|uniprotkb:A2AFJ9 intact:EBI-15985676|ensembl:ENSMUSP00000006311 psi-mi:vgll1_mouse(display_long)|uniprotkb:Vgll1(gene name)|psi-mi:Vgll1(display_short)|uniprotkb:Vestigial-related factor(gene name synonym) psi-mi:q62296-1(display_long)|uniprotkb:Tead4(gene name)|psi-mi:Tead4(display_short)|uniprotkb:Tcf13r1(gene name synonym)|uniprotkb:Tef3(gene name synonym)|uniprotkb:Tefr1(gene name synonym)|uniprotkb:TEFR1A(isoform synonym)|uniprotkb:ETFR-2A(isoform synonym)|uniprotkb:ETF-related factor 2(gene name synonym)|uniprotkb:TEA domain family member 4(gene name synonym)|uniprotkb:TEF-1-related factor 1(gene name synonym)|uniprotkb:TEF-1-related factor FR-19(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pobbati et al. (2012) pubmed:22632831|doi:10.1016/j.str.2012.04.004|imex:IM-18021 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15985805|imex:IM-18021-5|dip:DIP-189622E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031131(gene)|ensembl:ENSMUST00000033465(transcript)|ensembl:ENSMUST00000114745(transcript)|ensembl:ENSMUST00000114746(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|interpro:IPR011520(Vestigial/tondu)|rcsb pdb:5Z2Q|refseq:NP_001300692.1|refseq:NP_573514.1|dip:DIP-59848N intact:EBI-9253444(isoform-parent)|ensembl:ENSMUSG00000030353(gene)|ensembl:ENSMUST00000006311(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:2e9f+/WDpoxY0z0XQCSuU6vOL8M10090 rogid:AsL1gpxJ7abeFVwJyF1xUkc8Q2c10090 rigid:SInkJlyMWQLD95YRq+Qhr735Ts4 false myc tag:n-n ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)