#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q99598 uniprotkb:Q15631 intact:EBI-742638|intact:EBI-1050136|uniprotkb:B1APC6|refseq:NP_005990|dip:DIP-29463N intact:EBI-1044160|uniprotkb:Q5U0K7|ensembl:ENSP00000374332|uniprotkb:B7Z3X8 psi-mi:tsnax_human(display_long)|uniprotkb:Translin-associated factor X(gene name synonym)|uniprotkb:TSNAX(gene name)|psi-mi:TSNAX(display_short)|uniprotkb:TRAX(gene name synonym) psi-mi:tsn_human(display_long)|uniprotkb:TSN(gene name)|psi-mi:TSN(display_short)|uniprotkb:Component 3 of promoter of RISC(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Ye et al. (2011) pubmed:21552258|doi:10.1038/nsmb.2032|imex:IM-17491 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15925367|imex:IM-17491-3|dip:DIP-188777E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005634"(nucleus)|go:"GO:0008565"(obsolete protein transporter activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007283"(spermatogenesis)|refseq:NP_005990.1|interpro:IPR002848(Translin)|interpro:IPR016068(Translin, N-terminal)|rcsb pdb:3PJA|rcsb pdb:3QB5|ensembl:ENST00000366639|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031047"(gene silencing by RNA)|reactome:R-HSA-426486|go:"GO:0030422"(production of siRNA involved in RNA interference)|interpro:IPR036081|go:"GO:0003677"(DNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0046872"(metal ion binding)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000116918|ensembl:ENSP00000355599|go:"GO:0005654"(nucleoplasm)|go:"GO:0003723"(RNA binding)|dip:DIP-29463N|mint:MINT-1347706|go:"GO:0044822"|interpro:IPR016069(Translin, C-terminal)|go:"GO:0031687"(A2A adenosine receptor binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0003697"(single-stranded DNA binding) go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006310"(DNA recombination)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR002848(Translin)|interpro:IPR033956|interpro:IPR036081|mint:Q15631|rcsb pdb:1J1J|rcsb pdb:3PJA|interpro:IPR016068(Translin, N-terminal)|rcsb pdb:3QB5|rcsb pdb:4WYV|reactome:R-HSA-426486|interpro:IPR016069(Translin, C-terminal)|ensembl:ENSG00000211460(gene)|ensembl:ENST00000389682(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004613.1|refseq:NP_001248330.1|dip:DIP-42216N psi-mi:"MI:0465"(dip) crc64:D38B0DD96B50C0B9|no-uniprot-update:|caution:"The protein could not be merged with EBI-12908040 because of some conflicts with the protein sequence (features which cannot be shifted)." - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:TaNIxjLHGusdq32WbdJ21DG9yBQ9606 rogid:Gv/cF7n6u7XUAQMK/YVsJ0yG93I9606 rigid:b5gfboazpWS4obY1cBRkHIiSRZA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UKV8 uniprotkb:Q99598 intact:EBI-528269|uniprotkb:Q8TCZ5|uniprotkb:Q8WV58|uniprotkb:Q96ID1|ensembl:ENSP00000220592 intact:EBI-742638|intact:EBI-1050136|uniprotkb:B1APC6|refseq:NP_005990|dip:DIP-29463N psi-mi:ago2_human(display_long)|uniprotkb:AGO2(gene name)|psi-mi:AGO2(display_short)|uniprotkb:Argonaute RISC catalytic component 2(gene name synonym)|uniprotkb:EIF2C2(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2C 2(gene name synonym)|uniprotkb:PAZ Piwi domain protein(gene name synonym)|uniprotkb:Protein slicer(gene name synonym) psi-mi:tsnax_human(display_long)|uniprotkb:Translin-associated factor X(gene name synonym)|uniprotkb:TSNAX(gene name)|psi-mi:TSNAX(display_short)|uniprotkb:TRAX(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ye et al. (2011) pubmed:21552258|doi:10.1038/nsmb.2032|imex:IM-17491 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15925341|imex:IM-17491-2|dip:DIP-188783E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001158095.1|refseq:NP_036286.2|rcsb pdb:5T7B|rcsb pdb:5WEA|rcsb pdb:6CBD|rcsb pdb:6MDZ|rcsb pdb:6MFN|rcsb pdb:6MFR|rcsb pdb:6N4O|rcsb pdb:6NIT|rcsb pdb:6RA4|rcsb pdb:7C6B|rcsb pdb:7D7U|reactome:R-HSA-1912408|reactome:R-HSA-203927|reactome:R-HSA-4086398|reactome:R-HSA-426486|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|rcsb pdb:4F3T|rcsb pdb:4OLA|rcsb pdb:4OLB|rcsb pdb:4W5N|rcsb pdb:4W5O|rcsb pdb:4W5Q|rcsb pdb:4W5R|rcsb pdb:4W5T|rcsb pdb:4Z4C|rcsb pdb:4Z4D|rcsb pdb:4Z4E|rcsb pdb:4Z4F|rcsb pdb:4Z4G|rcsb pdb:4Z4H|rcsb pdb:4Z4I|rcsb pdb:5JS1|rcsb pdb:3QX9|rcsb pdb:5JS2|rcsb pdb:5KI6|ensembl:ENSG00000123908(gene)|ensembl:ENST00000220592(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006412"(translation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0030425"(dendrite)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0045975"(positive regulation of translation, ncRNA-mediated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0070551"(endoribonuclease activity, cleaving siRNA-paired mRNA)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0090624"(endoribonuclease activity, cleaving miRNA-paired mRNA)|go:"GO:0090625"(mRNA destabilization-mediated gene silencing by siRNA)|go:"GO:0098808"(mRNA cap binding)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR028602|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|interpro:IPR036085|interpro:IPR036397|mint:Q9UKV8|rcsb pdb:3LUC|rcsb pdb:3LUD|rcsb pdb:3LUG|rcsb pdb:3LUH|rcsb pdb:3LUJ|rcsb pdb:3LUK|rcsb pdb:3QX8|dip:DIP-29194N go:"GO:0005634"(nucleus)|go:"GO:0008565"(obsolete protein transporter activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007283"(spermatogenesis)|refseq:NP_005990.1|interpro:IPR002848(Translin)|interpro:IPR016068(Translin, N-terminal)|rcsb pdb:3PJA|rcsb pdb:3QB5|ensembl:ENST00000366639|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031047"(gene silencing by RNA)|reactome:R-HSA-426486|go:"GO:0030422"(production of siRNA involved in RNA interference)|interpro:IPR036081|go:"GO:0003677"(DNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0046872"(metal ion binding)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000116918|ensembl:ENSP00000355599|go:"GO:0005654"(nucleoplasm)|go:"GO:0003723"(RNA binding)|dip:DIP-29463N|mint:MINT-1347706|go:"GO:0044822"|interpro:IPR016069(Translin, C-terminal)|go:"GO:0031687"(A2A adenosine receptor binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0003697"(single-stranded DNA binding) psi-mi:"MI:0465"(dip) - crc64:D38B0DD96B50C0B9|no-uniprot-update:|caution:"The protein could not be merged with EBI-12908040 because of some conflicts with the protein sequence (features which cannot be shifted)." full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:8GU8wsz9kTG2ViT7pP7uQyYTVsc9606 rogid:TaNIxjLHGusdq32WbdJ21DG9yBQ9606 rigid:gJOcz6VR/NP1C+WisXTcJU0yF10 false flag tag:n-n his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UKV8 uniprotkb:Q15631 intact:EBI-528269|uniprotkb:Q8TCZ5|uniprotkb:Q8WV58|uniprotkb:Q96ID1|ensembl:ENSP00000220592 intact:EBI-1044160|uniprotkb:Q5U0K7|ensembl:ENSP00000374332|uniprotkb:B7Z3X8 psi-mi:ago2_human(display_long)|uniprotkb:AGO2(gene name)|psi-mi:AGO2(display_short)|uniprotkb:Argonaute RISC catalytic component 2(gene name synonym)|uniprotkb:EIF2C2(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2C 2(gene name synonym)|uniprotkb:PAZ Piwi domain protein(gene name synonym)|uniprotkb:Protein slicer(gene name synonym) psi-mi:tsn_human(display_long)|uniprotkb:TSN(gene name)|psi-mi:TSN(display_short)|uniprotkb:Component 3 of promoter of RISC(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ye et al. (2011) pubmed:21552258|doi:10.1038/nsmb.2032|imex:IM-17491 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15925341|imex:IM-17491-2|dip:DIP-188783E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001158095.1|refseq:NP_036286.2|rcsb pdb:5T7B|rcsb pdb:5WEA|rcsb pdb:6CBD|rcsb pdb:6MDZ|rcsb pdb:6MFN|rcsb pdb:6MFR|rcsb pdb:6N4O|rcsb pdb:6NIT|rcsb pdb:6RA4|rcsb pdb:7C6B|rcsb pdb:7D7U|reactome:R-HSA-1912408|reactome:R-HSA-203927|reactome:R-HSA-4086398|reactome:R-HSA-426486|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|rcsb pdb:4F3T|rcsb pdb:4OLA|rcsb pdb:4OLB|rcsb pdb:4W5N|rcsb pdb:4W5O|rcsb pdb:4W5Q|rcsb pdb:4W5R|rcsb pdb:4W5T|rcsb pdb:4Z4C|rcsb pdb:4Z4D|rcsb pdb:4Z4E|rcsb pdb:4Z4F|rcsb pdb:4Z4G|rcsb pdb:4Z4H|rcsb pdb:4Z4I|rcsb pdb:5JS1|rcsb pdb:3QX9|rcsb pdb:5JS2|rcsb pdb:5KI6|ensembl:ENSG00000123908(gene)|ensembl:ENST00000220592(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006412"(translation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0030425"(dendrite)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0045975"(positive regulation of translation, ncRNA-mediated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0070551"(endoribonuclease activity, cleaving siRNA-paired mRNA)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0090624"(endoribonuclease activity, cleaving miRNA-paired mRNA)|go:"GO:0090625"(mRNA destabilization-mediated gene silencing by siRNA)|go:"GO:0098808"(mRNA cap binding)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR028602|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|interpro:IPR036085|interpro:IPR036397|mint:Q9UKV8|rcsb pdb:3LUC|rcsb pdb:3LUD|rcsb pdb:3LUG|rcsb pdb:3LUH|rcsb pdb:3LUJ|rcsb pdb:3LUK|rcsb pdb:3QX8|dip:DIP-29194N go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006310"(DNA recombination)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR002848(Translin)|interpro:IPR033956|interpro:IPR036081|mint:Q15631|rcsb pdb:1J1J|rcsb pdb:3PJA|interpro:IPR016068(Translin, N-terminal)|rcsb pdb:3QB5|rcsb pdb:4WYV|reactome:R-HSA-426486|interpro:IPR016069(Translin, C-terminal)|ensembl:ENSG00000211460(gene)|ensembl:ENST00000389682(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004613.1|refseq:NP_001248330.1|dip:DIP-42216N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:8GU8wsz9kTG2ViT7pP7uQyYTVsc9606 rogid:Gv/cF7n6u7XUAQMK/YVsJ0yG93I9606 rigid:gJOcz6VR/NP1C+WisXTcJU0yF10 false flag tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99598 uniprotkb:Q15631 intact:EBI-742638|intact:EBI-1050136|uniprotkb:B1APC6|refseq:NP_005990|dip:DIP-29463N intact:EBI-1044160|uniprotkb:Q5U0K7|ensembl:ENSP00000374332|uniprotkb:B7Z3X8 psi-mi:tsnax_human(display_long)|uniprotkb:Translin-associated factor X(gene name synonym)|uniprotkb:TSNAX(gene name)|psi-mi:TSNAX(display_short)|uniprotkb:TRAX(gene name synonym) psi-mi:tsn_human(display_long)|uniprotkb:TSN(gene name)|psi-mi:TSN(display_short)|uniprotkb:Component 3 of promoter of RISC(gene name synonym) psi-mi:"MI:0096"(pull down) Ye et al. (2011) pubmed:21552258|doi:10.1038/nsmb.2032|imex:IM-17491 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15925320|imex:IM-17491-1|dip:DIP-188777E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005634"(nucleus)|go:"GO:0008565"(obsolete protein transporter activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007283"(spermatogenesis)|refseq:NP_005990.1|interpro:IPR002848(Translin)|interpro:IPR016068(Translin, N-terminal)|rcsb pdb:3PJA|rcsb pdb:3QB5|ensembl:ENST00000366639|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031047"(gene silencing by RNA)|reactome:R-HSA-426486|go:"GO:0030422"(production of siRNA involved in RNA interference)|interpro:IPR036081|go:"GO:0003677"(DNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0046872"(metal ion binding)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000116918|ensembl:ENSP00000355599|go:"GO:0005654"(nucleoplasm)|go:"GO:0003723"(RNA binding)|dip:DIP-29463N|mint:MINT-1347706|go:"GO:0044822"|interpro:IPR016069(Translin, C-terminal)|go:"GO:0031687"(A2A adenosine receptor binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0003697"(single-stranded DNA binding) go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006310"(DNA recombination)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR002848(Translin)|interpro:IPR033956|interpro:IPR036081|mint:Q15631|rcsb pdb:1J1J|rcsb pdb:3PJA|interpro:IPR016068(Translin, N-terminal)|rcsb pdb:3QB5|rcsb pdb:4WYV|reactome:R-HSA-426486|interpro:IPR016069(Translin, C-terminal)|ensembl:ENSG00000211460(gene)|ensembl:ENST00000389682(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004613.1|refseq:NP_001248330.1|dip:DIP-42216N psi-mi:"MI:0465"(dip) crc64:D38B0DD96B50C0B9|no-uniprot-update:|caution:"The protein could not be merged with EBI-12908040 because of some conflicts with the protein sequence (features which cannot be shifted)." - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:TaNIxjLHGusdq32WbdJ21DG9yBQ9606 rogid:Gv/cF7n6u7XUAQMK/YVsJ0yG93I9606 rigid:b5gfboazpWS4obY1cBRkHIiSRZA false his tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99598 uniprotkb:Q15631 intact:EBI-742638|intact:EBI-1050136|uniprotkb:B1APC6|refseq:NP_005990|dip:DIP-29463N intact:EBI-1044160|uniprotkb:Q5U0K7|ensembl:ENSP00000374332|uniprotkb:B7Z3X8 psi-mi:tsnax_human(display_long)|uniprotkb:Translin-associated factor X(gene name synonym)|uniprotkb:TSNAX(gene name)|psi-mi:TSNAX(display_short)|uniprotkb:TRAX(gene name synonym) psi-mi:tsn_human(display_long)|uniprotkb:TSN(gene name)|psi-mi:TSN(display_short)|uniprotkb:Component 3 of promoter of RISC(gene name synonym) psi-mi:"MI:0226"(ion exchange chromatography) Ye et al. (2011) pubmed:21552258|doi:10.1038/nsmb.2032|imex:IM-17491 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15925418|imex:IM-17491-6|dip:DIP-188777E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005634"(nucleus)|go:"GO:0008565"(obsolete protein transporter activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007283"(spermatogenesis)|refseq:NP_005990.1|interpro:IPR002848(Translin)|interpro:IPR016068(Translin, N-terminal)|rcsb pdb:3PJA|rcsb pdb:3QB5|ensembl:ENST00000366639|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031047"(gene silencing by RNA)|reactome:R-HSA-426486|go:"GO:0030422"(production of siRNA involved in RNA interference)|interpro:IPR036081|go:"GO:0003677"(DNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0046872"(metal ion binding)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000116918|ensembl:ENSP00000355599|go:"GO:0005654"(nucleoplasm)|go:"GO:0003723"(RNA binding)|dip:DIP-29463N|mint:MINT-1347706|go:"GO:0044822"|interpro:IPR016069(Translin, C-terminal)|go:"GO:0031687"(A2A adenosine receptor binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0003697"(single-stranded DNA binding) go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006310"(DNA recombination)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR002848(Translin)|interpro:IPR033956|interpro:IPR036081|mint:Q15631|rcsb pdb:1J1J|rcsb pdb:3PJA|interpro:IPR016068(Translin, N-terminal)|rcsb pdb:3QB5|rcsb pdb:4WYV|reactome:R-HSA-426486|interpro:IPR016069(Translin, C-terminal)|ensembl:ENSG00000211460(gene)|ensembl:ENST00000389682(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004613.1|refseq:NP_001248330.1|dip:DIP-42216N psi-mi:"MI:0465"(dip) crc64:D38B0DD96B50C0B9|no-uniprot-update:|caution:"The protein could not be merged with EBI-12908040 because of some conflicts with the protein sequence (features which cannot be shifted)." - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:TaNIxjLHGusdq32WbdJ21DG9yBQ9606 rogid:Gv/cF7n6u7XUAQMK/YVsJ0yG93I9606 rigid:b5gfboazpWS4obY1cBRkHIiSRZA false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q99598 uniprotkb:Q15631 intact:EBI-742638|intact:EBI-1050136|uniprotkb:B1APC6|refseq:NP_005990|dip:DIP-29463N intact:EBI-1044160|uniprotkb:Q5U0K7|ensembl:ENSP00000374332|uniprotkb:B7Z3X8 psi-mi:tsnax_human(display_long)|uniprotkb:Translin-associated factor X(gene name synonym)|uniprotkb:TSNAX(gene name)|psi-mi:TSNAX(display_short)|uniprotkb:TRAX(gene name synonym) psi-mi:tsn_human(display_long)|uniprotkb:TSN(gene name)|psi-mi:TSN(display_short)|uniprotkb:Component 3 of promoter of RISC(gene name synonym) psi-mi:"MI:0226"(ion exchange chromatography) Ye et al. (2011) pubmed:21552258|doi:10.1038/nsmb.2032|imex:IM-17491 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15925401|imex:IM-17491-5|dip:DIP-188777E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005634"(nucleus)|go:"GO:0008565"(obsolete protein transporter activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007283"(spermatogenesis)|refseq:NP_005990.1|interpro:IPR002848(Translin)|interpro:IPR016068(Translin, N-terminal)|rcsb pdb:3PJA|rcsb pdb:3QB5|ensembl:ENST00000366639|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031047"(gene silencing by RNA)|reactome:R-HSA-426486|go:"GO:0030422"(production of siRNA involved in RNA interference)|interpro:IPR036081|go:"GO:0003677"(DNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0046872"(metal ion binding)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000116918|ensembl:ENSP00000355599|go:"GO:0005654"(nucleoplasm)|go:"GO:0003723"(RNA binding)|dip:DIP-29463N|mint:MINT-1347706|go:"GO:0044822"|interpro:IPR016069(Translin, C-terminal)|go:"GO:0031687"(A2A adenosine receptor binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0003697"(single-stranded DNA binding) go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006310"(DNA recombination)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR002848(Translin)|interpro:IPR033956|interpro:IPR036081|mint:Q15631|rcsb pdb:1J1J|rcsb pdb:3PJA|interpro:IPR016068(Translin, N-terminal)|rcsb pdb:3QB5|rcsb pdb:4WYV|reactome:R-HSA-426486|interpro:IPR016069(Translin, C-terminal)|ensembl:ENSG00000211460(gene)|ensembl:ENST00000389682(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004613.1|refseq:NP_001248330.1|dip:DIP-42216N psi-mi:"MI:0465"(dip) crc64:D38B0DD96B50C0B9|no-uniprot-update:|caution:"The protein could not be merged with EBI-12908040 because of some conflicts with the protein sequence (features which cannot be shifted)." - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:TaNIxjLHGusdq32WbdJ21DG9yBQ9606 rogid:Gv/cF7n6u7XUAQMK/YVsJ0yG93I9606 rigid:b5gfboazpWS4obY1cBRkHIiSRZA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99598 uniprotkb:Q15631 intact:EBI-742638|intact:EBI-1050136|uniprotkb:B1APC6|refseq:NP_005990|dip:DIP-29463N intact:EBI-1044160|uniprotkb:Q5U0K7|ensembl:ENSP00000374332|uniprotkb:B7Z3X8 psi-mi:tsnax_human(display_long)|uniprotkb:Translin-associated factor X(gene name synonym)|uniprotkb:TSNAX(gene name)|psi-mi:TSNAX(display_short)|uniprotkb:TRAX(gene name synonym) psi-mi:tsn_human(display_long)|uniprotkb:TSN(gene name)|psi-mi:TSN(display_short)|uniprotkb:Component 3 of promoter of RISC(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Ye et al. (2011) pubmed:21552258|doi:10.1038/nsmb.2032|imex:IM-17491 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15925384|imex:IM-17491-4|dip:DIP-188777E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005634"(nucleus)|go:"GO:0008565"(obsolete protein transporter activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007283"(spermatogenesis)|refseq:NP_005990.1|interpro:IPR002848(Translin)|interpro:IPR016068(Translin, N-terminal)|rcsb pdb:3PJA|rcsb pdb:3QB5|ensembl:ENST00000366639|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031047"(gene silencing by RNA)|reactome:R-HSA-426486|go:"GO:0030422"(production of siRNA involved in RNA interference)|interpro:IPR036081|go:"GO:0003677"(DNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0046872"(metal ion binding)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000116918|ensembl:ENSP00000355599|go:"GO:0005654"(nucleoplasm)|go:"GO:0003723"(RNA binding)|dip:DIP-29463N|mint:MINT-1347706|go:"GO:0044822"|interpro:IPR016069(Translin, C-terminal)|go:"GO:0031687"(A2A adenosine receptor binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0003697"(single-stranded DNA binding) go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006310"(DNA recombination)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR002848(Translin)|interpro:IPR033956|interpro:IPR036081|mint:Q15631|rcsb pdb:1J1J|rcsb pdb:3PJA|interpro:IPR016068(Translin, N-terminal)|rcsb pdb:3QB5|rcsb pdb:4WYV|reactome:R-HSA-426486|interpro:IPR016069(Translin, C-terminal)|ensembl:ENSG00000211460(gene)|ensembl:ENST00000389682(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004613.1|refseq:NP_001248330.1|dip:DIP-42216N psi-mi:"MI:0465"(dip) crc64:D38B0DD96B50C0B9|no-uniprot-update:|caution:"The protein could not be merged with EBI-12908040 because of some conflicts with the protein sequence (features which cannot be shifted)." - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:TaNIxjLHGusdq32WbdJ21DG9yBQ9606 rogid:Gv/cF7n6u7XUAQMK/YVsJ0yG93I9606 rigid:b5gfboazpWS4obY1cBRkHIiSRZA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99598 uniprotkb:Q15631 intact:EBI-742638|intact:EBI-1050136|uniprotkb:B1APC6|refseq:NP_005990|dip:DIP-29463N intact:EBI-1044160|uniprotkb:Q5U0K7|ensembl:ENSP00000374332|uniprotkb:B7Z3X8 psi-mi:tsnax_human(display_long)|uniprotkb:Translin-associated factor X(gene name synonym)|uniprotkb:TSNAX(gene name)|psi-mi:TSNAX(display_short)|uniprotkb:TRAX(gene name synonym) psi-mi:tsn_human(display_long)|uniprotkb:TSN(gene name)|psi-mi:TSN(display_short)|uniprotkb:Component 3 of promoter of RISC(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Ye et al. (2011) pubmed:21552258|doi:10.1038/nsmb.2032|imex:IM-17491 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15925435|imex:IM-17491-7|dip:DIP-188777E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005634"(nucleus)|go:"GO:0008565"(obsolete protein transporter activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007283"(spermatogenesis)|refseq:NP_005990.1|interpro:IPR002848(Translin)|interpro:IPR016068(Translin, N-terminal)|rcsb pdb:3PJA|rcsb pdb:3QB5|ensembl:ENST00000366639|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031047"(gene silencing by RNA)|reactome:R-HSA-426486|go:"GO:0030422"(production of siRNA involved in RNA interference)|interpro:IPR036081|go:"GO:0003677"(DNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0046872"(metal ion binding)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000116918|ensembl:ENSP00000355599|go:"GO:0005654"(nucleoplasm)|go:"GO:0003723"(RNA binding)|dip:DIP-29463N|mint:MINT-1347706|go:"GO:0044822"|interpro:IPR016069(Translin, C-terminal)|go:"GO:0031687"(A2A adenosine receptor binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0003697"(single-stranded DNA binding) go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006310"(DNA recombination)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR002848(Translin)|interpro:IPR033956|interpro:IPR036081|mint:Q15631|rcsb pdb:1J1J|rcsb pdb:3PJA|interpro:IPR016068(Translin, N-terminal)|rcsb pdb:3QB5|rcsb pdb:4WYV|reactome:R-HSA-426486|interpro:IPR016069(Translin, C-terminal)|ensembl:ENSG00000211460(gene)|ensembl:ENST00000389682(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004613.1|refseq:NP_001248330.1|dip:DIP-42216N psi-mi:"MI:0465"(dip) crc64:D38B0DD96B50C0B9|no-uniprot-update:|caution:"The protein could not be merged with EBI-12908040 because of some conflicts with the protein sequence (features which cannot be shifted)." - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:TaNIxjLHGusdq32WbdJ21DG9yBQ9606 rogid:Gv/cF7n6u7XUAQMK/YVsJ0yG93I9606 rigid:b5gfboazpWS4obY1cBRkHIiSRZA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)