#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q14213 uniprotkb:Q8NEV9 intact:EBI-742959|ensembl:ENSP00000221847|uniprotkb:O75269|uniprotkb:A0N0N2 intact:EBI-15887997|ensembl:ENSP00000349365|uniprotkb:A0N0L2|uniprotkb:Q6P676 psi-mi:il27b_human(display_long)|uniprotkb:Epstein-Barr virus-induced gene 3 protein(gene name synonym)|uniprotkb:EBI3(gene name)|psi-mi:EBI3(display_short)|uniprotkb:IL27B(gene name synonym) psi-mi:il27a_human(display_long)|uniprotkb:Interleukin-30(gene name synonym)|uniprotkb:p28(gene name synonym)|uniprotkb:IL27(gene name)|psi-mi:IL27(display_short)|uniprotkb:IL27A(gene name synonym)|uniprotkb:IL30(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Rousseau et al. (2010) pubmed:20974977|doi:10.1073/pnas.1005793107|imex:IM-17116 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15888027|imex:IM-17116-1|dip:DIP-188105E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105246(gene)|ensembl:ENST00000221847(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0006959"(humoral immune response)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0017046"(peptide hormone binding)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0043235"(receptor complex)|go:"GO:0046641"(positive regulation of alpha-beta T cell proliferation)|interpro:IPR003530(Long hematopoietin receptor, soluble alpha chain, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|reactome:R-HSA-8984722|reactome:R-HSA-9020956|refseq:NP_005746.2|refseq:XP_011525921.1|dip:DIP-57556N ensembl:ENSG00000197272(gene)|ensembl:ENST00000356897(transcript)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0009617"(response to bacterium)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0045087"(innate immune response)|go:"GO:0045523"(interleukin-27 receptor binding)|interpro:IPR009079(Four-helical cytokine-like, core)|interpro:IPR026207|reactome:R-HSA-9020956|go:"GO:0045625"(regulation of T-helper 1 cell differentiation)|refseq:NP_663634.2|dip:DIP-59473N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) - 2017/08/06 2017/08/10 rogid:1ToLHzGfj3MUAHODaUHILDkE/wc9606 rogid:vKzcGLx7DjxDr0fXMfDa4v8TE+89606 rigid:h2dfzEdpT9/9TANxM1mczbJpFBw false flag tag:c-c mutation disrupting interaction:97-97|v5 tag:c-c|mutation increasing interaction:197-197 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14213 uniprotkb:Q8NEV9 intact:EBI-742959|ensembl:ENSP00000221847|uniprotkb:O75269|uniprotkb:A0N0N2 intact:EBI-15887997|ensembl:ENSP00000349365|uniprotkb:A0N0L2|uniprotkb:Q6P676 psi-mi:il27b_human(display_long)|uniprotkb:Epstein-Barr virus-induced gene 3 protein(gene name synonym)|uniprotkb:EBI3(gene name)|psi-mi:EBI3(display_short)|uniprotkb:IL27B(gene name synonym) psi-mi:il27a_human(display_long)|uniprotkb:Interleukin-30(gene name synonym)|uniprotkb:p28(gene name synonym)|uniprotkb:IL27(gene name)|psi-mi:IL27(display_short)|uniprotkb:IL27A(gene name synonym)|uniprotkb:IL30(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Rousseau et al. (2010) pubmed:20974977|doi:10.1073/pnas.1005793107|imex:IM-17116 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15888054|imex:IM-17116-2|dip:DIP-188105E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105246(gene)|ensembl:ENST00000221847(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0006959"(humoral immune response)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0017046"(peptide hormone binding)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0043235"(receptor complex)|go:"GO:0046641"(positive regulation of alpha-beta T cell proliferation)|interpro:IPR003530(Long hematopoietin receptor, soluble alpha chain, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|reactome:R-HSA-8984722|reactome:R-HSA-9020956|refseq:NP_005746.2|refseq:XP_011525921.1|dip:DIP-57556N ensembl:ENSG00000197272(gene)|ensembl:ENST00000356897(transcript)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0009617"(response to bacterium)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0045087"(innate immune response)|go:"GO:0045523"(interleukin-27 receptor binding)|interpro:IPR009079(Four-helical cytokine-like, core)|interpro:IPR026207|reactome:R-HSA-9020956|go:"GO:0045625"(regulation of T-helper 1 cell differentiation)|refseq:NP_663634.2|dip:DIP-59473N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) - 2017/08/06 2017/08/10 rogid:1ToLHzGfj3MUAHODaUHILDkE/wc9606 rogid:vKzcGLx7DjxDr0fXMfDa4v8TE+89606 rigid:h2dfzEdpT9/9TANxM1mczbJpFBw false flag tag:c-c|mutation decreasing interaction:159-159|mutation disrupting interaction:210-210|mutation decreasing interaction:97-97 v5 tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)