#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q12046	uniprotkb:P32523	intact:EBI-553|ensemblfungi:YDL209C|uniprotkb:D6VRE5	intact:EBI-493|uniprotkb:Q07870|ensemblfungi:YLL036C|uniprotkb:D6VXW9	psi-mi:cwc2_yeast(display_long)|uniprotkb:CWC2(gene name)|psi-mi:CWC2(display_short)|uniprotkb:YDL209C(locus name)|uniprotkb:D1041(orf name)|uniprotkb:NTC40(gene name synonym)|uniprotkb:SLC3(gene name synonym)|uniprotkb:Complexed with CEF1 protein 2(gene name synonym)|uniprotkb:PRP19-associated complex protein 40(gene name synonym)|uniprotkb:Synthetic lethal with CLF1 protein 3(gene name synonym)	psi-mi:prp19_yeast(display_long)|uniprotkb:PRP19(gene name)|psi-mi:PRP19(display_short)|uniprotkb:PSO4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PRP19(gene name synonym)|uniprotkb:YLL036C(locus name)	psi-mi:"MI:0018"(two hybrid)	Vander et al. (2010)	pubmed:20462492|doi:10.1016/j.str.2010.02.015|imex:IM-15929	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15853764|imex:IM-15929-1|dip:DIP-83468E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR032297|interpro:IPR034181|interpro:IPR035979|interpro:IPR039171|interpro:IPR039173|rcsb pdb:3TP2|rcsb pdb:3U1L|rcsb pdb:3U1M|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|refseq:NP_010072.1|sgd:S000002368|ensemblfungi:YDL209C(gene)|ensemblfungi:YDL209C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0007049"(cell cycle)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0046872"(metal ion binding)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|rcsb pdb:6J6Q|dip:DIP-5164N	refseq:NP_013064.1|sgd:S000003959|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR038959|rcsb pdb:1N87|rcsb pdb:2BAY|rcsb pdb:3LRV|rcsb pdb:4ZB4|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ5|rcsb pdb:5M8C|rcsb pdb:5MQ0|ensemblfungi:YLL036C(gene)|ensemblfungi:YLL036C_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000974"(Prp19 complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0042802"(identical protein binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR003613(U box)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013915(Pre-mRNA-splicing factor 19)|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|dip:DIP-1112N|mint:P32523	psi-mi:"MI:0465"(dip)	crc64:371734A11DFDB339	crc64:A44D8C7DD6F64185	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:bCvRFfQxZ4QaBZqqOyQP7ye/UeQ559292	rogid:/oQc2rJZ7WcCIx7cnqE6XSW/3Vk559292	rigid:19svEltBUYs4ilzutfD7YZc6g3k	false	-	mutation decreasing interaction:387-387|mutation disrupting interaction:403-403|mutation disrupting interaction:404-404,403-403|mutation decreasing interaction:404-404|mutation decreasing interaction:341-341	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12046	uniprotkb:P32523	intact:EBI-553|ensemblfungi:YDL209C|uniprotkb:D6VRE5	intact:EBI-493|uniprotkb:Q07870|ensemblfungi:YLL036C|uniprotkb:D6VXW9	psi-mi:cwc2_yeast(display_long)|uniprotkb:CWC2(gene name)|psi-mi:CWC2(display_short)|uniprotkb:YDL209C(locus name)|uniprotkb:D1041(orf name)|uniprotkb:NTC40(gene name synonym)|uniprotkb:SLC3(gene name synonym)|uniprotkb:Complexed with CEF1 protein 2(gene name synonym)|uniprotkb:PRP19-associated complex protein 40(gene name synonym)|uniprotkb:Synthetic lethal with CLF1 protein 3(gene name synonym)	psi-mi:prp19_yeast(display_long)|uniprotkb:PRP19(gene name)|psi-mi:PRP19(display_short)|uniprotkb:PSO4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PRP19(gene name synonym)|uniprotkb:YLL036C(locus name)	psi-mi:"MI:0028"(cosedimentation in solution)	Vander et al. (2010)	pubmed:20462492|doi:10.1016/j.str.2010.02.015|imex:IM-15929	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15853797|imex:IM-15929-2|dip:DIP-83468E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR032297|interpro:IPR034181|interpro:IPR035979|interpro:IPR039171|interpro:IPR039173|rcsb pdb:3TP2|rcsb pdb:3U1L|rcsb pdb:3U1M|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|refseq:NP_010072.1|sgd:S000002368|ensemblfungi:YDL209C(gene)|ensemblfungi:YDL209C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0007049"(cell cycle)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0046872"(metal ion binding)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|rcsb pdb:6J6Q|dip:DIP-5164N	refseq:NP_013064.1|sgd:S000003959|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR038959|rcsb pdb:1N87|rcsb pdb:2BAY|rcsb pdb:3LRV|rcsb pdb:4ZB4|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ5|rcsb pdb:5M8C|rcsb pdb:5MQ0|ensemblfungi:YLL036C(gene)|ensemblfungi:YLL036C_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000974"(Prp19 complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0042802"(identical protein binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR003613(U box)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013915(Pre-mRNA-splicing factor 19)|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|dip:DIP-1112N|mint:P32523	psi-mi:"MI:0465"(dip)	crc64:371734A11DFDB339	crc64:A44D8C7DD6F64185	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:bCvRFfQxZ4QaBZqqOyQP7ye/UeQ559292	rogid:/oQc2rJZ7WcCIx7cnqE6XSW/3Vk559292	rigid:19svEltBUYs4ilzutfD7YZc6g3k	false	-	sufficient binding region:165-503	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P87126	uniprotkb:P87126	intact:EBI-538799|ensemblfungi:"SPAC3A12.11c.1:pep"|uniprotkb:Q9P8I7	intact:EBI-538799|ensemblfungi:"SPAC3A12.11c.1:pep"|uniprotkb:Q9P8I7	psi-mi:cwc2_schpo(display_long)|uniprotkb:Complexed with cdc5 protein 2(gene name synonym)|uniprotkb:Pre-mRNA-processing protein 3(gene name synonym)|uniprotkb:prp3(gene name synonym)|uniprotkb:cwf2(gene name)|psi-mi:cwf2(display_short)|uniprotkb:SPAC3A12.11c(orf name)	psi-mi:cwc2_schpo(display_long)|uniprotkb:Complexed with cdc5 protein 2(gene name synonym)|uniprotkb:Pre-mRNA-processing protein 3(gene name synonym)|uniprotkb:prp3(gene name synonym)|uniprotkb:cwf2(gene name)|psi-mi:cwf2(display_short)|uniprotkb:SPAC3A12.11c(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Vander et al. (2010)	pubmed:20462492|doi:10.1016/j.str.2010.02.015|imex:IM-15929	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15853816|imex:IM-15929-3|dip:DIP-186326E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:SPAC3A12.11c(gene)|ensemblfungi:SPAC3A12.11c.1(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000974"(Prp19 complex)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0007049"(cell cycle)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0036002"(pre-mRNA binding)|refseq:NP_593337.1|go:"GO:0046872"(metal ion binding)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR032297|interpro:IPR034181|interpro:IPR035979|interpro:IPR036855|interpro:IPR039171|interpro:IPR039173|rcsb pdb:3JB9|dip:DIP-34853N	ensemblfungi:SPAC3A12.11c(gene)|ensemblfungi:SPAC3A12.11c.1(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000974"(Prp19 complex)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0007049"(cell cycle)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0036002"(pre-mRNA binding)|refseq:NP_593337.1|go:"GO:0046872"(metal ion binding)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR032297|interpro:IPR034181|interpro:IPR035979|interpro:IPR036855|interpro:IPR039171|interpro:IPR039173|rcsb pdb:3JB9|dip:DIP-34853N	psi-mi:"MI:0465"(dip)	crc64:5CD36A5C880077DE	crc64:5CD36A5C880077DE	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)")	-	2017/08/06	2017/08/10	rogid:DCN6yHmQcPJXwojGWzHzc/E/QL8284812	rogid:DCN6yHmQcPJXwojGWzHzc/E/QL8284812	rigid:4Qt/YM8UgQyAiFrRGRJBORC2+Es	false	myc tag:c-c	green fluorescent protein tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q12046	uniprotkb:P32523	intact:EBI-553|ensemblfungi:YDL209C|uniprotkb:D6VRE5	intact:EBI-493|uniprotkb:Q07870|ensemblfungi:YLL036C|uniprotkb:D6VXW9	psi-mi:cwc2_yeast(display_long)|uniprotkb:CWC2(gene name)|psi-mi:CWC2(display_short)|uniprotkb:YDL209C(locus name)|uniprotkb:D1041(orf name)|uniprotkb:NTC40(gene name synonym)|uniprotkb:SLC3(gene name synonym)|uniprotkb:Complexed with CEF1 protein 2(gene name synonym)|uniprotkb:PRP19-associated complex protein 40(gene name synonym)|uniprotkb:Synthetic lethal with CLF1 protein 3(gene name synonym)	psi-mi:prp19_yeast(display_long)|uniprotkb:PRP19(gene name)|psi-mi:PRP19(display_short)|uniprotkb:PSO4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PRP19(gene name synonym)|uniprotkb:YLL036C(locus name)	psi-mi:"MI:0071"(molecular sieving)	Vander et al. (2010)	pubmed:20462492|doi:10.1016/j.str.2010.02.015|imex:IM-15929	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15853837|imex:IM-15929-4|dip:DIP-83468E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR032297|interpro:IPR034181|interpro:IPR035979|interpro:IPR039171|interpro:IPR039173|rcsb pdb:3TP2|rcsb pdb:3U1L|rcsb pdb:3U1M|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|refseq:NP_010072.1|sgd:S000002368|ensemblfungi:YDL209C(gene)|ensemblfungi:YDL209C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0007049"(cell cycle)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0046872"(metal ion binding)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|rcsb pdb:6J6Q|dip:DIP-5164N	refseq:NP_013064.1|sgd:S000003959|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR038959|rcsb pdb:1N87|rcsb pdb:2BAY|rcsb pdb:3LRV|rcsb pdb:4ZB4|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ5|rcsb pdb:5M8C|rcsb pdb:5MQ0|ensemblfungi:YLL036C(gene)|ensemblfungi:YLL036C_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000974"(Prp19 complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0042802"(identical protein binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR003613(U box)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013915(Pre-mRNA-splicing factor 19)|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|dip:DIP-1112N|mint:P32523	psi-mi:"MI:0465"(dip)	crc64:371734A11DFDB339	crc64:A44D8C7DD6F64185	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:bCvRFfQxZ4QaBZqqOyQP7ye/UeQ559292	rogid:/oQc2rJZ7WcCIx7cnqE6XSW/3Vk559292	rigid:19svEltBUYs4ilzutfD7YZc6g3k	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q12046	uniprotkb:P32523	intact:EBI-553|ensemblfungi:YDL209C|uniprotkb:D6VRE5	intact:EBI-493|uniprotkb:Q07870|ensemblfungi:YLL036C|uniprotkb:D6VXW9	psi-mi:cwc2_yeast(display_long)|uniprotkb:CWC2(gene name)|psi-mi:CWC2(display_short)|uniprotkb:YDL209C(locus name)|uniprotkb:D1041(orf name)|uniprotkb:NTC40(gene name synonym)|uniprotkb:SLC3(gene name synonym)|uniprotkb:Complexed with CEF1 protein 2(gene name synonym)|uniprotkb:PRP19-associated complex protein 40(gene name synonym)|uniprotkb:Synthetic lethal with CLF1 protein 3(gene name synonym)	psi-mi:prp19_yeast(display_long)|uniprotkb:PRP19(gene name)|psi-mi:PRP19(display_short)|uniprotkb:PSO4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PRP19(gene name synonym)|uniprotkb:YLL036C(locus name)	psi-mi:"MI:0096"(pull down)	Vander et al. (2010)	pubmed:20462492|doi:10.1016/j.str.2010.02.015|imex:IM-15929	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15853854|imex:IM-15929-5|dip:DIP-83468E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR032297|interpro:IPR034181|interpro:IPR035979|interpro:IPR039171|interpro:IPR039173|rcsb pdb:3TP2|rcsb pdb:3U1L|rcsb pdb:3U1M|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|refseq:NP_010072.1|sgd:S000002368|ensemblfungi:YDL209C(gene)|ensemblfungi:YDL209C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0007049"(cell cycle)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0046872"(metal ion binding)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|rcsb pdb:6J6Q|dip:DIP-5164N	refseq:NP_013064.1|sgd:S000003959|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR038959|rcsb pdb:1N87|rcsb pdb:2BAY|rcsb pdb:3LRV|rcsb pdb:4ZB4|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ5|rcsb pdb:5M8C|rcsb pdb:5MQ0|ensemblfungi:YLL036C(gene)|ensemblfungi:YLL036C_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000974"(Prp19 complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0042802"(identical protein binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR003613(U box)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013915(Pre-mRNA-splicing factor 19)|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|dip:DIP-1112N|mint:P32523	psi-mi:"MI:0465"(dip)	crc64:371734A11DFDB339	crc64:A44D8C7DD6F64185	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/06	2017/08/10	rogid:bCvRFfQxZ4QaBZqqOyQP7ye/UeQ559292	rogid:/oQc2rJZ7WcCIx7cnqE6XSW/3Vk559292	rigid:19svEltBUYs4ilzutfD7YZc6g3k	false	his tag:n-n|sufficient binding region:228-339	mutation disrupting interaction:404-404,403-403|sufficient binding region:165-503	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P39964	uniprotkb:O14011	intact:EBI-538771|ensemblfungi:"SPAC644.12.1:pep"	intact:EBI-590830|ensemblfungi:"SPAC29A4.08c.1:pep"	psi-mi:cef1_schpo(display_long)|uniprotkb:Cell division control protein 5(gene name synonym)|uniprotkb:SPAC644.12(orf name)|uniprotkb:cdc5(gene name)|psi-mi:cdc5(display_short)	psi-mi:prp19_schpo(display_long)|uniprotkb:prp19(gene name)|psi-mi:prp19(display_short)|uniprotkb:Complexed with cdc5 protein 8(gene name synonym)|uniprotkb:cwf8(gene name synonym)|uniprotkb:SPAC29A4.08c(orf name)|uniprotkb:RING-type E3 ubiquitin transferase PRP19(gene name synonym)	psi-mi:"MI:0096"(pull down)	Vander et al. (2010)	pubmed:20462492|doi:10.1016/j.str.2010.02.015|imex:IM-15929	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15853881|imex:IM-15929-6|dip:DIP-186327E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_593880.1|ensemblfungi:SPAC644.12(gene)|ensemblfungi:SPAC644.12.1(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR021786|rcsb pdb:3JB9|dip:DIP-34817N	ensemblfungi:SPAC29A4.08c(gene)|ensemblfungi:SPAC29A4.08c.1(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000974"(Prp19 complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR003613(U box)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013915(Pre-mRNA-splicing factor 19)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR036322|interpro:IPR038959|rcsb pdb:3JB9|reactome:R-SPO-6781823|refseq:NP_594874.1|reactome:R-SPO-6782135|reactome:R-SPO-6782210|dip:DIP-34861N	psi-mi:"MI:0465"(dip)	crc64:9FCA639A2F9A9E84	crc64:3900431C90A94A41	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)")	-	2017/08/06	2017/08/10	rogid:vcTncFbysTij/H+MOPYgTp1dojo284812	rogid:+vJVXNhcae9jQAZ4MMncnAx7Gjk284812	rigid:HYR8iR3GjhWZOKlm+cpKtn/ScEA	false	tandem tag:c-c	myc tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39964	uniprotkb:P87126	intact:EBI-538771|ensemblfungi:"SPAC644.12.1:pep"	intact:EBI-538799|ensemblfungi:"SPAC3A12.11c.1:pep"|uniprotkb:Q9P8I7	psi-mi:cef1_schpo(display_long)|uniprotkb:Cell division control protein 5(gene name synonym)|uniprotkb:SPAC644.12(orf name)|uniprotkb:cdc5(gene name)|psi-mi:cdc5(display_short)	psi-mi:cwc2_schpo(display_long)|uniprotkb:Complexed with cdc5 protein 2(gene name synonym)|uniprotkb:Pre-mRNA-processing protein 3(gene name synonym)|uniprotkb:prp3(gene name synonym)|uniprotkb:cwf2(gene name)|psi-mi:cwf2(display_short)|uniprotkb:SPAC3A12.11c(orf name)	psi-mi:"MI:0096"(pull down)	Vander et al. (2010)	pubmed:20462492|doi:10.1016/j.str.2010.02.015|imex:IM-15929	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15853881|imex:IM-15929-6|dip:DIP-186327E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_593880.1|ensemblfungi:SPAC644.12(gene)|ensemblfungi:SPAC644.12.1(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR021786|rcsb pdb:3JB9|dip:DIP-34817N	ensemblfungi:SPAC3A12.11c(gene)|ensemblfungi:SPAC3A12.11c.1(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000974"(Prp19 complex)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0007049"(cell cycle)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0036002"(pre-mRNA binding)|refseq:NP_593337.1|go:"GO:0046872"(metal ion binding)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR032297|interpro:IPR034181|interpro:IPR035979|interpro:IPR036855|interpro:IPR039171|interpro:IPR039173|rcsb pdb:3JB9|dip:DIP-34853N	psi-mi:"MI:0465"(dip)	crc64:9FCA639A2F9A9E84	crc64:5CD36A5C880077DE	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)")	-	2017/08/06	2017/08/10	rogid:vcTncFbysTij/H+MOPYgTp1dojo284812	rogid:DCN6yHmQcPJXwojGWzHzc/E/QL8284812	rigid:HYR8iR3GjhWZOKlm+cpKtn/ScEA	false	tandem tag:c-c	myc tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32523	uniprotkb:P32523	intact:EBI-493|uniprotkb:Q07870|ensemblfungi:YLL036C|uniprotkb:D6VXW9	intact:EBI-493|uniprotkb:Q07870|ensemblfungi:YLL036C|uniprotkb:D6VXW9	psi-mi:prp19_yeast(display_long)|uniprotkb:PRP19(gene name)|psi-mi:PRP19(display_short)|uniprotkb:PSO4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PRP19(gene name synonym)|uniprotkb:YLL036C(locus name)	psi-mi:prp19_yeast(display_long)|uniprotkb:PRP19(gene name)|psi-mi:PRP19(display_short)|uniprotkb:PSO4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PRP19(gene name synonym)|uniprotkb:YLL036C(locus name)	psi-mi:"MI:0028"(cosedimentation in solution)	Vander et al. (2010)	pubmed:20462492|doi:10.1016/j.str.2010.02.015|imex:IM-15929	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15853905|imex:IM-15929-7|dip:DIP-3866E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013064.1|sgd:S000003959|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR038959|rcsb pdb:1N87|rcsb pdb:2BAY|rcsb pdb:3LRV|rcsb pdb:4ZB4|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ5|rcsb pdb:5M8C|rcsb pdb:5MQ0|ensemblfungi:YLL036C(gene)|ensemblfungi:YLL036C_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000974"(Prp19 complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0042802"(identical protein binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR003613(U box)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013915(Pre-mRNA-splicing factor 19)|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|dip:DIP-1112N|mint:P32523	refseq:NP_013064.1|sgd:S000003959|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR038959|rcsb pdb:1N87|rcsb pdb:2BAY|rcsb pdb:3LRV|rcsb pdb:4ZB4|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ5|rcsb pdb:5M8C|rcsb pdb:5MQ0|ensemblfungi:YLL036C(gene)|ensemblfungi:YLL036C_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000974"(Prp19 complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0042802"(identical protein binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR003613(U box)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013915(Pre-mRNA-splicing factor 19)|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|dip:DIP-1112N|mint:P32523	psi-mi:"MI:0465"(dip)	crc64:A44D8C7DD6F64185	crc64:A44D8C7DD6F64185	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/06	2017/08/10	rogid:/oQc2rJZ7WcCIx7cnqE6XSW/3Vk559292	rogid:/oQc2rJZ7WcCIx7cnqE6XSW/3Vk559292	rigid:7nwC0bwQm0f65jf4pK6AaYg+lWs	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)