#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9VUQ5	uniprotkb:Q9IJX4	intact:EBI-442476|ensemblmetazoa:FBpp0075312|uniprotkb:Q2Q3Y0|uniprotkb:Q2Q3Y1|uniprotkb:Q2Q3Y3|uniprotkb:Q2Q3Y4|uniprotkb:Q2Q3Y5|uniprotkb:Q86P07|uniprotkb:C7LAD2|uniprotkb:Q8T3N2|uniprotkb:Q9VUQ6|intact:EBI-3430439	intact:EBI-15848754	psi-mi:ago2_drome(display_long)|uniprotkb:AGO2(gene name)|psi-mi:AGO2(display_short)|uniprotkb:CG7439(orf name)	psi-mi:poln_crpvc(display_long)|uniprotkb:ORF1(orf name)	psi-mi:"MI:0096"(pull down)	Nayak et al. (2010)	pubmed:20400949|doi:10.1038/nsmb.1810|imex:IM-15949	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:928300(crpvc)|taxid:928300(crpvc)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15848776|imex:IM-15949-1|dip:DIP-186371E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:FBgn0087035(gene)|ensemblmetazoa:FBtr0075559(transcript)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007279"(pole cell formation)|go:"GO:0007349"(cellularization)|go:"GO:0007367"(segment polarity determination)|go:"GO:0009047"(dosage compensation by hyperactivation of X chromosome)|go:"GO:0009616"(RNAi-mediated antiviral immune response)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016246"(RNA interference)|go:"GO:0016442"(RISC complex)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0033227"(dsRNA transport)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035190"(syncytial nuclear migration)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0070551"(endoribonuclease activity, cleaving siRNA-paired mRNA)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0070922"(small RNA loading onto RISC)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:0098586"(cellular response to virus)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|interpro:IPR036085|interpro:IPR036397|mint:Q9VUQ5|rcsb pdb:1R6Z|rcsb pdb:1T2R|rcsb pdb:1T2S|rcsb pdb:1VYN|rcsb pdb:3MJ0|reactome:R-DME-203927|reactome:R-DME-426486|reactome:R-DME-426496|go:"GO:0035197"(siRNA binding)|refseq:NP_648775.1|refseq:NP_730054.1|flybase:FBgn0087035|dip:DIP-41570N	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0060698"(endoribonuclease inhibitor activity)|go:"GO:0140533"(suppression of host RNAi-mediated antiviral immune response)|interpro:IPR000605(Helicase, superfamily 3, single-stranded DNA/RNA virus)|interpro:IPR001205(RNA-directed RNA polymerase, P3D protein)|interpro:IPR004004(Helicase/polymerase/peptidase polyprotein, Calicivirus)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR014759(Helicase, superfamily 3, single-stranded RNA virus)|interpro:IPR024387|interpro:IPR043128|interpro:IPR043502|interpro:IPR043504|interpro:IPR044067|rcsb pdb:6C3R|go:"GO:0060702"(negative regulation of endoribonuclease activity)|dip:DIP-59000N|refseq:NP_647481.1	psi-mi:"MI:0465"(dip)	-	crc64:78C5969469EAA716	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	-	2017/08/06	2017/08/10	rogid:Y3Jc/eqc+QUJupZ169PcsPduqro7227	rogid:z6mQQxKh8ME7ceRwqW7+iWNnUGk928300	rigid:T2QDhlCIwbYweMJbGPo8JEYMdLQ	false	-	binding-associated region:1-148|his tag:c-c	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9VUQ5	uniprotkb:Q9IJX4	intact:EBI-442476|ensemblmetazoa:FBpp0075312|uniprotkb:Q2Q3Y0|uniprotkb:Q2Q3Y1|uniprotkb:Q2Q3Y3|uniprotkb:Q2Q3Y4|uniprotkb:Q2Q3Y5|uniprotkb:Q86P07|uniprotkb:C7LAD2|uniprotkb:Q8T3N2|uniprotkb:Q9VUQ6|intact:EBI-3430439	intact:EBI-15848754	psi-mi:ago2_drome(display_long)|uniprotkb:AGO2(gene name)|psi-mi:AGO2(display_short)|uniprotkb:CG7439(orf name)	psi-mi:poln_crpvc(display_long)|uniprotkb:ORF1(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Nayak et al. (2010)	pubmed:20400949|doi:10.1038/nsmb.1810|imex:IM-15949	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:928300(crpvc)|taxid:928300(crpvc)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15848797|imex:IM-15949-2|dip:DIP-186371E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:FBgn0087035(gene)|ensemblmetazoa:FBtr0075559(transcript)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007279"(pole cell formation)|go:"GO:0007349"(cellularization)|go:"GO:0007367"(segment polarity determination)|go:"GO:0009047"(dosage compensation by hyperactivation of X chromosome)|go:"GO:0009616"(RNAi-mediated antiviral immune response)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016246"(RNA interference)|go:"GO:0016442"(RISC complex)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0033227"(dsRNA transport)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035190"(syncytial nuclear migration)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0070551"(endoribonuclease activity, cleaving siRNA-paired mRNA)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0070922"(small RNA loading onto RISC)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:0098586"(cellular response to virus)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|interpro:IPR036085|interpro:IPR036397|mint:Q9VUQ5|rcsb pdb:1R6Z|rcsb pdb:1T2R|rcsb pdb:1T2S|rcsb pdb:1VYN|rcsb pdb:3MJ0|reactome:R-DME-203927|reactome:R-DME-426486|reactome:R-DME-426496|go:"GO:0035197"(siRNA binding)|refseq:NP_648775.1|refseq:NP_730054.1|flybase:FBgn0087035|dip:DIP-41570N	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0060698"(endoribonuclease inhibitor activity)|go:"GO:0140533"(suppression of host RNAi-mediated antiviral immune response)|interpro:IPR000605(Helicase, superfamily 3, single-stranded DNA/RNA virus)|interpro:IPR001205(RNA-directed RNA polymerase, P3D protein)|interpro:IPR004004(Helicase/polymerase/peptidase polyprotein, Calicivirus)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR014759(Helicase, superfamily 3, single-stranded RNA virus)|interpro:IPR024387|interpro:IPR043128|interpro:IPR043502|interpro:IPR043504|interpro:IPR044067|rcsb pdb:6C3R|go:"GO:0060702"(negative regulation of endoribonuclease activity)|dip:DIP-59000N|refseq:NP_647481.1	psi-mi:"MI:0465"(dip)	-	crc64:78C5969469EAA716	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	-	2017/08/06	2017/08/10	rogid:Y3Jc/eqc+QUJupZ169PcsPduqro7227	rogid:z6mQQxKh8ME7ceRwqW7+iWNnUGk928300	rigid:T2QDhlCIwbYweMJbGPo8JEYMdLQ	false	-	flag tag:c-c|binding-associated region:1-148	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9VUQ5	uniprotkb:Q9IJX4	intact:EBI-442476|ensemblmetazoa:FBpp0075312|uniprotkb:Q2Q3Y0|uniprotkb:Q2Q3Y1|uniprotkb:Q2Q3Y3|uniprotkb:Q2Q3Y4|uniprotkb:Q2Q3Y5|uniprotkb:Q86P07|uniprotkb:C7LAD2|uniprotkb:Q8T3N2|uniprotkb:Q9VUQ6|intact:EBI-3430439	intact:EBI-15848754	psi-mi:ago2_drome(display_long)|uniprotkb:AGO2(gene name)|psi-mi:AGO2(display_short)|uniprotkb:CG7439(orf name)	psi-mi:poln_crpvc(display_long)|uniprotkb:ORF1(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Nayak et al. (2010)	pubmed:20400949|doi:10.1038/nsmb.1810|imex:IM-15949	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:928300(crpvc)|taxid:928300(crpvc)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15848818|imex:IM-15949-3|dip:DIP-186371E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:FBgn0087035(gene)|ensemblmetazoa:FBtr0075559(transcript)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007279"(pole cell formation)|go:"GO:0007349"(cellularization)|go:"GO:0007367"(segment polarity determination)|go:"GO:0009047"(dosage compensation by hyperactivation of X chromosome)|go:"GO:0009616"(RNAi-mediated antiviral immune response)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016246"(RNA interference)|go:"GO:0016442"(RISC complex)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0033227"(dsRNA transport)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035190"(syncytial nuclear migration)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0070551"(endoribonuclease activity, cleaving siRNA-paired mRNA)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0070922"(small RNA loading onto RISC)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:0098586"(cellular response to virus)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|interpro:IPR036085|interpro:IPR036397|mint:Q9VUQ5|rcsb pdb:1R6Z|rcsb pdb:1T2R|rcsb pdb:1T2S|rcsb pdb:1VYN|rcsb pdb:3MJ0|reactome:R-DME-203927|reactome:R-DME-426486|reactome:R-DME-426496|go:"GO:0035197"(siRNA binding)|refseq:NP_648775.1|refseq:NP_730054.1|flybase:FBgn0087035|dip:DIP-41570N	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0060698"(endoribonuclease inhibitor activity)|go:"GO:0140533"(suppression of host RNAi-mediated antiviral immune response)|interpro:IPR000605(Helicase, superfamily 3, single-stranded DNA/RNA virus)|interpro:IPR001205(RNA-directed RNA polymerase, P3D protein)|interpro:IPR004004(Helicase/polymerase/peptidase polyprotein, Calicivirus)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR014759(Helicase, superfamily 3, single-stranded RNA virus)|interpro:IPR024387|interpro:IPR043128|interpro:IPR043502|interpro:IPR043504|interpro:IPR044067|rcsb pdb:6C3R|go:"GO:0060702"(negative regulation of endoribonuclease activity)|dip:DIP-59000N|refseq:NP_647481.1	psi-mi:"MI:0465"(dip)	-	crc64:78C5969469EAA716	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	-	2017/08/06	2017/08/10	rogid:Y3Jc/eqc+QUJupZ169PcsPduqro7227	rogid:z6mQQxKh8ME7ceRwqW7+iWNnUGk928300	rigid:T2QDhlCIwbYweMJbGPo8JEYMdLQ	false	-	flag tag:c-c|binding-associated region:1-148	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)