#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O62305 uniprotkb:O62305 intact:EBI-313095|uniprotkb:A5JYT0|uniprotkb:A7LPH2|uniprotkb:B3GWC8|uniprotkb:O62304|uniprotkb:Q21431|uniprotkb:Q7JLT8|uniprotkb:Q9NG91|uniprotkb:Q9NH55|uniprotkb:Q9NH56|uniprotkb:Q9NH57|uniprotkb:Q9NH58|uniprotkb:Q9NH59|uniprotkb:Q9NH60|uniprotkb:Q9U6Q0 intact:EBI-313095|uniprotkb:A5JYT0|uniprotkb:A7LPH2|uniprotkb:B3GWC8|uniprotkb:O62304|uniprotkb:Q21431|uniprotkb:Q7JLT8|uniprotkb:Q9NG91|uniprotkb:Q9NH55|uniprotkb:Q9NH56|uniprotkb:Q9NH57|uniprotkb:Q9NH58|uniprotkb:Q9NH59|uniprotkb:Q9NH60|uniprotkb:Q9U6Q0 psi-mi:kcc2d_caeel(display_long)|uniprotkb:unc-43(gene name)|psi-mi:unc-43(display_short)|uniprotkb:Uncoordinated protein 43(gene name synonym)|uniprotkb:K11E8.1(orf name) psi-mi:kcc2d_caeel(display_long)|uniprotkb:unc-43(gene name)|psi-mi:unc-43(display_short)|uniprotkb:Uncoordinated protein 43(gene name synonym)|uniprotkb:K11E8.1(orf name) psi-mi:"MI:0071"(molecular sieving) Chao et al. (2010) pubmed:20139983|doi:10.1038/nsmb.1751|imex:IM-15931 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15834384|imex:IM-15931-1|dip:DIP-186329E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001023293.2|refseq:NP_001023294.1|refseq:NP_001023296.1|refseq:NP_001023297.1|refseq:NP_001023298.1|refseq:NP_001023299.1|refseq:NP_001023300.1|refseq:NP_001023301.1|refseq:NP_001023302.1|refseq:NP_001023303.1|refseq:NP_001023304.1|refseq:NP_001122788.1|refseq:NP_001122789.1|refseq:NP_001129863.1|wormbase:K11E8.1a|wormbase:K11E8.1b|wormbase:K11E8.1d|wormbase:K11E8.1e|wormbase:K11E8.1f|wormbase:K11E8.1g|wormbase:K11E8.1h|wormbase:K11E8.1i|wormbase:K11E8.1k|wormbase:K11E8.1l|wormbase:K11E8.1m|wormbase:K11E8.1n|wormbase:K11E8.1o|wormbase:K11E8.1p|go:"GO:0000165"(MAPK cascade)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0042427"(serotonin biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0072375"(medium-term memory)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904115"(axon cytoplasm)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|rcsb pdb:2BDW|rcsb pdb:2F86|rcsb pdb:3KK8|rcsb pdb:3KK9|rcsb pdb:3KL8|dip:DIP-25971N|dip:DIP-58986N|reactome:R-CEL-3371571|reactome:R-CEL-4086398|reactome:R-CEL-438066|reactome:R-CEL-5578775|reactome:R-CEL-936837 refseq:NP_001023293.2|refseq:NP_001023294.1|refseq:NP_001023296.1|refseq:NP_001023297.1|refseq:NP_001023298.1|refseq:NP_001023299.1|refseq:NP_001023300.1|refseq:NP_001023301.1|refseq:NP_001023302.1|refseq:NP_001023303.1|refseq:NP_001023304.1|refseq:NP_001122788.1|refseq:NP_001122789.1|refseq:NP_001129863.1|wormbase:K11E8.1a|wormbase:K11E8.1b|wormbase:K11E8.1d|wormbase:K11E8.1e|wormbase:K11E8.1f|wormbase:K11E8.1g|wormbase:K11E8.1h|wormbase:K11E8.1i|wormbase:K11E8.1k|wormbase:K11E8.1l|wormbase:K11E8.1m|wormbase:K11E8.1n|wormbase:K11E8.1o|wormbase:K11E8.1p|go:"GO:0000165"(MAPK cascade)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0042427"(serotonin biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0072375"(medium-term memory)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904115"(axon cytoplasm)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|rcsb pdb:2BDW|rcsb pdb:2F86|rcsb pdb:3KK8|rcsb pdb:3KK9|rcsb pdb:3KL8|dip:DIP-25971N|dip:DIP-58986N|reactome:R-CEL-3371571|reactome:R-CEL-4086398|reactome:R-CEL-438066|reactome:R-CEL-5578775|reactome:R-CEL-936837 psi-mi:"MI:0465"(dip) caution:This sequence has been withdrawn from Uniprot.|crc64:3231366FFF81A695 caution:This sequence has been withdrawn from Uniprot.|crc64:3231366FFF81A695 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:C4NFZBXWJlS7vjsWwkCSwnf76zM6239 rogid:C4NFZBXWJlS7vjsWwkCSwnf76zM6239 rigid:ANVzzWvxBO0d0bsBoyTrTSTXt+Q false sufficient binding region:1-291 sufficient binding region:1-291 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P62149 uniprotkb:O62305 intact:EBI-4421710|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q5ZIQ6|uniprotkb:Q61379|uniprotkb:Q61380|ensembl:ENSGALP00000016260|ensembl:ENSGALP00000042446 intact:EBI-313095|uniprotkb:A5JYT0|uniprotkb:A7LPH2|uniprotkb:B3GWC8|uniprotkb:O62304|uniprotkb:Q21431|uniprotkb:Q7JLT8|uniprotkb:Q9NG91|uniprotkb:Q9NH55|uniprotkb:Q9NH56|uniprotkb:Q9NH57|uniprotkb:Q9NH58|uniprotkb:Q9NH59|uniprotkb:Q9NH60|uniprotkb:Q9U6Q0 psi-mi:calm_chick(display_long)|uniprotkb:CALM(gene name)|psi-mi:CALM(display_short)|uniprotkb:CAM(gene name synonym)|uniprotkb:RCJMB04_24e7(orf name) psi-mi:kcc2d_caeel(display_long)|uniprotkb:unc-43(gene name)|psi-mi:unc-43(display_short)|uniprotkb:Uncoordinated protein 43(gene name synonym)|uniprotkb:K11E8.1(orf name) psi-mi:"MI:0071"(molecular sieving) Chao et al. (2010) pubmed:20139983|doi:10.1038/nsmb.1751|imex:IM-15931 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15834402|imex:IM-15931-2|dip:DIP-186331E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-29154N|ensembl:ENSGALG00000010023(gene)|ensembl:ENSGALG00000026445(gene)|ensembl:ENSGALT00000016279(transcript)|ensembl:ENSGALT00000045488(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0017022"(myosin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051401"(CH domain binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|rcsb pdb:1AHR|rcsb pdb:1UP5|rcsb pdb:2BCX|rcsb pdb:2BKI|rcsb pdb:2KZ2|rcsb pdb:2M3S|rcsb pdb:2O5G|rcsb pdb:2O60|rcsb pdb:2VB6|rcsb pdb:3GOF|rcsb pdb:3GP2|rcsb pdb:4BYA|rcsb pdb:5HIT|rcsb pdb:6BNV refseq:NP_001023293.2|refseq:NP_001023294.1|refseq:NP_001023296.1|refseq:NP_001023297.1|refseq:NP_001023298.1|refseq:NP_001023299.1|refseq:NP_001023300.1|refseq:NP_001023301.1|refseq:NP_001023302.1|refseq:NP_001023303.1|refseq:NP_001023304.1|refseq:NP_001122788.1|refseq:NP_001122789.1|refseq:NP_001129863.1|wormbase:K11E8.1a|wormbase:K11E8.1b|wormbase:K11E8.1d|wormbase:K11E8.1e|wormbase:K11E8.1f|wormbase:K11E8.1g|wormbase:K11E8.1h|wormbase:K11E8.1i|wormbase:K11E8.1k|wormbase:K11E8.1l|wormbase:K11E8.1m|wormbase:K11E8.1n|wormbase:K11E8.1o|wormbase:K11E8.1p|go:"GO:0000165"(MAPK cascade)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0042427"(serotonin biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0072375"(medium-term memory)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904115"(axon cytoplasm)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|rcsb pdb:2BDW|rcsb pdb:2F86|rcsb pdb:3KK8|rcsb pdb:3KK9|rcsb pdb:3KL8|dip:DIP-25971N|dip:DIP-58986N|reactome:R-CEL-3371571|reactome:R-CEL-4086398|reactome:R-CEL-438066|reactome:R-CEL-5578775|reactome:R-CEL-936837 psi-mi:"MI:0465"(dip) - caution:This sequence has been withdrawn from Uniprot.|crc64:3231366FFF81A695 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:tTYcOd9bOh211njZVz7cYVybAMQ9031 rogid:C4NFZBXWJlS7vjsWwkCSwnf76zM6239 rigid:2hPxQElhCmo9pv/81vLSKriVShc false - binding-associated region:1-340 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O62305 uniprotkb:O62305 intact:EBI-313095|uniprotkb:A5JYT0|uniprotkb:A7LPH2|uniprotkb:B3GWC8|uniprotkb:O62304|uniprotkb:Q21431|uniprotkb:Q7JLT8|uniprotkb:Q9NG91|uniprotkb:Q9NH55|uniprotkb:Q9NH56|uniprotkb:Q9NH57|uniprotkb:Q9NH58|uniprotkb:Q9NH59|uniprotkb:Q9NH60|uniprotkb:Q9U6Q0 intact:EBI-313095|uniprotkb:A5JYT0|uniprotkb:A7LPH2|uniprotkb:B3GWC8|uniprotkb:O62304|uniprotkb:Q21431|uniprotkb:Q7JLT8|uniprotkb:Q9NG91|uniprotkb:Q9NH55|uniprotkb:Q9NH56|uniprotkb:Q9NH57|uniprotkb:Q9NH58|uniprotkb:Q9NH59|uniprotkb:Q9NH60|uniprotkb:Q9U6Q0 psi-mi:kcc2d_caeel(display_long)|uniprotkb:unc-43(gene name)|psi-mi:unc-43(display_short)|uniprotkb:Uncoordinated protein 43(gene name synonym)|uniprotkb:K11E8.1(orf name) psi-mi:kcc2d_caeel(display_long)|uniprotkb:unc-43(gene name)|psi-mi:unc-43(display_short)|uniprotkb:Uncoordinated protein 43(gene name synonym)|uniprotkb:K11E8.1(orf name) psi-mi:"MI:0067"(light scattering) Chao et al. (2010) pubmed:20139983|doi:10.1038/nsmb.1751|imex:IM-15931 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15834421|imex:IM-15931-3|dip:DIP-186329E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001023293.2|refseq:NP_001023294.1|refseq:NP_001023296.1|refseq:NP_001023297.1|refseq:NP_001023298.1|refseq:NP_001023299.1|refseq:NP_001023300.1|refseq:NP_001023301.1|refseq:NP_001023302.1|refseq:NP_001023303.1|refseq:NP_001023304.1|refseq:NP_001122788.1|refseq:NP_001122789.1|refseq:NP_001129863.1|wormbase:K11E8.1a|wormbase:K11E8.1b|wormbase:K11E8.1d|wormbase:K11E8.1e|wormbase:K11E8.1f|wormbase:K11E8.1g|wormbase:K11E8.1h|wormbase:K11E8.1i|wormbase:K11E8.1k|wormbase:K11E8.1l|wormbase:K11E8.1m|wormbase:K11E8.1n|wormbase:K11E8.1o|wormbase:K11E8.1p|go:"GO:0000165"(MAPK cascade)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0042427"(serotonin biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0072375"(medium-term memory)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904115"(axon cytoplasm)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|rcsb pdb:2BDW|rcsb pdb:2F86|rcsb pdb:3KK8|rcsb pdb:3KK9|rcsb pdb:3KL8|dip:DIP-25971N|dip:DIP-58986N|reactome:R-CEL-3371571|reactome:R-CEL-4086398|reactome:R-CEL-438066|reactome:R-CEL-5578775|reactome:R-CEL-936837 refseq:NP_001023293.2|refseq:NP_001023294.1|refseq:NP_001023296.1|refseq:NP_001023297.1|refseq:NP_001023298.1|refseq:NP_001023299.1|refseq:NP_001023300.1|refseq:NP_001023301.1|refseq:NP_001023302.1|refseq:NP_001023303.1|refseq:NP_001023304.1|refseq:NP_001122788.1|refseq:NP_001122789.1|refseq:NP_001129863.1|wormbase:K11E8.1a|wormbase:K11E8.1b|wormbase:K11E8.1d|wormbase:K11E8.1e|wormbase:K11E8.1f|wormbase:K11E8.1g|wormbase:K11E8.1h|wormbase:K11E8.1i|wormbase:K11E8.1k|wormbase:K11E8.1l|wormbase:K11E8.1m|wormbase:K11E8.1n|wormbase:K11E8.1o|wormbase:K11E8.1p|go:"GO:0000165"(MAPK cascade)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0042427"(serotonin biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0072375"(medium-term memory)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904115"(axon cytoplasm)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|rcsb pdb:2BDW|rcsb pdb:2F86|rcsb pdb:3KK8|rcsb pdb:3KK9|rcsb pdb:3KL8|dip:DIP-25971N|dip:DIP-58986N|reactome:R-CEL-3371571|reactome:R-CEL-4086398|reactome:R-CEL-438066|reactome:R-CEL-5578775|reactome:R-CEL-936837 psi-mi:"MI:0465"(dip) caution:This sequence has been withdrawn from Uniprot.|crc64:3231366FFF81A695 caution:This sequence has been withdrawn from Uniprot.|crc64:3231366FFF81A695 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:C4NFZBXWJlS7vjsWwkCSwnf76zM6239 rogid:C4NFZBXWJlS7vjsWwkCSwnf76zM6239 rigid:ANVzzWvxBO0d0bsBoyTrTSTXt+Q false sufficient binding region:1-291 sufficient binding region:1-291 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JI15 uniprotkb:O62305 intact:EBI-15834440|ensembl:ENSRNOP00000021864 intact:EBI-313095|uniprotkb:A5JYT0|uniprotkb:A7LPH2|uniprotkb:B3GWC8|uniprotkb:O62304|uniprotkb:Q21431|uniprotkb:Q7JLT8|uniprotkb:Q9NG91|uniprotkb:Q9NH55|uniprotkb:Q9NH56|uniprotkb:Q9NH57|uniprotkb:Q9NH58|uniprotkb:Q9NH59|uniprotkb:Q9NH60|uniprotkb:Q9U6Q0 psi-mi:ck2n1_rat(display_long)|uniprotkb:Camk2n1(gene name)|psi-mi:Camk2n1(display_short)|uniprotkb:calcium/calmodulin-dependent protein kinase II inhibitor alpha(gene name synonym) psi-mi:kcc2d_caeel(display_long)|uniprotkb:unc-43(gene name)|psi-mi:unc-43(display_short)|uniprotkb:Uncoordinated protein 43(gene name synonym)|uniprotkb:K11E8.1(orf name) psi-mi:"MI:0114"(x-ray crystallography) Chao et al. (2010) pubmed:20139983|doi:10.1038/nsmb.1751|imex:IM-15931 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15834462|imex:IM-15931-4|dip:DIP-186330E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000016322(gene)|ensembl:ENSRNOT00000021864(transcript)|go:"GO:0003084"(positive regulation of systemic arterial blood pressure)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008427"(calcium-dependent protein kinase inhibitor activity)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030425"(dendrite)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|interpro:IPR026779|rcsb pdb:3KL8|refseq:NP_775459.1|rgd:708430|dip:DIP-58987N refseq:NP_001023293.2|refseq:NP_001023294.1|refseq:NP_001023296.1|refseq:NP_001023297.1|refseq:NP_001023298.1|refseq:NP_001023299.1|refseq:NP_001023300.1|refseq:NP_001023301.1|refseq:NP_001023302.1|refseq:NP_001023303.1|refseq:NP_001023304.1|refseq:NP_001122788.1|refseq:NP_001122789.1|refseq:NP_001129863.1|wormbase:K11E8.1a|wormbase:K11E8.1b|wormbase:K11E8.1d|wormbase:K11E8.1e|wormbase:K11E8.1f|wormbase:K11E8.1g|wormbase:K11E8.1h|wormbase:K11E8.1i|wormbase:K11E8.1k|wormbase:K11E8.1l|wormbase:K11E8.1m|wormbase:K11E8.1n|wormbase:K11E8.1o|wormbase:K11E8.1p|go:"GO:0000165"(MAPK cascade)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0042427"(serotonin biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0072375"(medium-term memory)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904115"(axon cytoplasm)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|rcsb pdb:2BDW|rcsb pdb:2F86|rcsb pdb:3KK8|rcsb pdb:3KK9|rcsb pdb:3KL8|dip:DIP-25971N|dip:DIP-58986N|reactome:R-CEL-3371571|reactome:R-CEL-4086398|reactome:R-CEL-438066|reactome:R-CEL-5578775|reactome:R-CEL-936837 psi-mi:"MI:0465"(dip) - caution:This sequence has been withdrawn from Uniprot.|crc64:3231366FFF81A695 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:KQ8N/AejbmfbL1uBc12WmNFbpYg10116 rogid:C4NFZBXWJlS7vjsWwkCSwnf76zM6239 rigid:G7R5vKleONgVsVWaYe3YMxy4esI false binding-associated region:42-62 binding-associated region:1-272 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O62305 uniprotkb:O62305 intact:EBI-313095|uniprotkb:A5JYT0|uniprotkb:A7LPH2|uniprotkb:B3GWC8|uniprotkb:O62304|uniprotkb:Q21431|uniprotkb:Q7JLT8|uniprotkb:Q9NG91|uniprotkb:Q9NH55|uniprotkb:Q9NH56|uniprotkb:Q9NH57|uniprotkb:Q9NH58|uniprotkb:Q9NH59|uniprotkb:Q9NH60|uniprotkb:Q9U6Q0 intact:EBI-313095|uniprotkb:A5JYT0|uniprotkb:A7LPH2|uniprotkb:B3GWC8|uniprotkb:O62304|uniprotkb:Q21431|uniprotkb:Q7JLT8|uniprotkb:Q9NG91|uniprotkb:Q9NH55|uniprotkb:Q9NH56|uniprotkb:Q9NH57|uniprotkb:Q9NH58|uniprotkb:Q9NH59|uniprotkb:Q9NH60|uniprotkb:Q9U6Q0 psi-mi:kcc2d_caeel(display_long)|uniprotkb:unc-43(gene name)|psi-mi:unc-43(display_short)|uniprotkb:Uncoordinated protein 43(gene name synonym)|uniprotkb:K11E8.1(orf name) psi-mi:kcc2d_caeel(display_long)|uniprotkb:unc-43(gene name)|psi-mi:unc-43(display_short)|uniprotkb:Uncoordinated protein 43(gene name synonym)|uniprotkb:K11E8.1(orf name) psi-mi:"MI:0114"(x-ray crystallography) Chao et al. (2010) pubmed:20139983|doi:10.1038/nsmb.1751|imex:IM-15931 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15834485|imex:IM-15931-5|dip:DIP-186329E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001023293.2|refseq:NP_001023294.1|refseq:NP_001023296.1|refseq:NP_001023297.1|refseq:NP_001023298.1|refseq:NP_001023299.1|refseq:NP_001023300.1|refseq:NP_001023301.1|refseq:NP_001023302.1|refseq:NP_001023303.1|refseq:NP_001023304.1|refseq:NP_001122788.1|refseq:NP_001122789.1|refseq:NP_001129863.1|wormbase:K11E8.1a|wormbase:K11E8.1b|wormbase:K11E8.1d|wormbase:K11E8.1e|wormbase:K11E8.1f|wormbase:K11E8.1g|wormbase:K11E8.1h|wormbase:K11E8.1i|wormbase:K11E8.1k|wormbase:K11E8.1l|wormbase:K11E8.1m|wormbase:K11E8.1n|wormbase:K11E8.1o|wormbase:K11E8.1p|go:"GO:0000165"(MAPK cascade)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0042427"(serotonin biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0072375"(medium-term memory)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904115"(axon cytoplasm)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|rcsb pdb:2BDW|rcsb pdb:2F86|rcsb pdb:3KK8|rcsb pdb:3KK9|rcsb pdb:3KL8|dip:DIP-25971N|dip:DIP-58986N|reactome:R-CEL-3371571|reactome:R-CEL-4086398|reactome:R-CEL-438066|reactome:R-CEL-5578775|reactome:R-CEL-936837 refseq:NP_001023293.2|refseq:NP_001023294.1|refseq:NP_001023296.1|refseq:NP_001023297.1|refseq:NP_001023298.1|refseq:NP_001023299.1|refseq:NP_001023300.1|refseq:NP_001023301.1|refseq:NP_001023302.1|refseq:NP_001023303.1|refseq:NP_001023304.1|refseq:NP_001122788.1|refseq:NP_001122789.1|refseq:NP_001129863.1|wormbase:K11E8.1a|wormbase:K11E8.1b|wormbase:K11E8.1d|wormbase:K11E8.1e|wormbase:K11E8.1f|wormbase:K11E8.1g|wormbase:K11E8.1h|wormbase:K11E8.1i|wormbase:K11E8.1k|wormbase:K11E8.1l|wormbase:K11E8.1m|wormbase:K11E8.1n|wormbase:K11E8.1o|wormbase:K11E8.1p|go:"GO:0000165"(MAPK cascade)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0042427"(serotonin biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0072375"(medium-term memory)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904115"(axon cytoplasm)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|rcsb pdb:2BDW|rcsb pdb:2F86|rcsb pdb:3KK8|rcsb pdb:3KK9|rcsb pdb:3KL8|dip:DIP-25971N|dip:DIP-58986N|reactome:R-CEL-3371571|reactome:R-CEL-4086398|reactome:R-CEL-438066|reactome:R-CEL-5578775|reactome:R-CEL-936837 psi-mi:"MI:0465"(dip) caution:This sequence has been withdrawn from Uniprot.|crc64:3231366FFF81A695 caution:This sequence has been withdrawn from Uniprot.|crc64:3231366FFF81A695 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:C4NFZBXWJlS7vjsWwkCSwnf76zM6239 rogid:C4NFZBXWJlS7vjsWwkCSwnf76zM6239 rigid:ANVzzWvxBO0d0bsBoyTrTSTXt+Q false binding-associated region:1-289 binding-associated region:1-289 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)