#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P18847	uniprotkb:P18848	intact:EBI-712767|ensembl:ENSP00000344352|ensembl:ENSP00000355954|uniprotkb:Q5VTZ2|uniprotkb:Q6ICQ9|uniprotkb:Q7Z566|uniprotkb:Q8WYM6	intact:EBI-492498|uniprotkb:Q9UH31|ensembl:ENSP00000336790|ensembl:ENSP00000379912|ensembl:ENSP00000501783|ensembl:ENSP00000501863|ensembl:ENSP00000502400|ensembl:ENSP00000502610|ensembl:ENSP00000505360|ensembl:ENSP00000384587|intact:EBI-740263|uniprotkb:Q96AQ3	psi-mi:atf3_human(display_long)|uniprotkb:Activating transcription factor 3(gene name synonym)|uniprotkb:ATF3(gene name)|psi-mi:ATF3(display_short)	psi-mi:atf4_human(display_long)|uniprotkb:Activating transcription factor 4(gene name synonym)|uniprotkb:CREB2(gene name synonym)|uniprotkb:ATF4(gene name)|psi-mi:ATF4(display_short)|uniprotkb:TXREB(gene name synonym)|uniprotkb:Cyclic AMP-responsive element-binding protein 2(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 67(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wang et al. (2009)	pubmed:19164757|doi:10.1073/pnas.0807611106|imex:IM-14575	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15752938|imex:IM-14575-1|dip:DIP-103518E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162772(gene)|ensembl:ENST00000341491(transcript)|ensembl:ENST00000366987(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061394"(regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1903984"(positive regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029812|mint:P18847|reactome:R-HSA-380994|reactome:R-HSA-9633012|reactome:R-HSA-9648895|refseq:NP_001025458.1|refseq:NP_001665.1|refseq:XP_011507881.1|refseq:NP_001035709.1|refseq:NP_001193413.2|refseq:NP_001193415.1|refseq:NP_001193417.2|refseq:XP_005273203.1|dip:DIP-344N	refseq:NP_001666.2|refseq:NP_877962.1|ensembl:ENSG00000128272(gene)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0070982"(L-asparagine metabolic process)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140467"(integrated stress response signaling)|go:"GO:0140468"(HRI-mediated signaling)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990037"(Lewy body core)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990589"(ATF4-CREB1 transcription factor complex)|go:"GO:1990590"(ATF1-ATF4 transcription factor complex)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029811|mint:P18848|rcsb pdb:1CI6|reactome:R-HSA-380994|reactome:R-HSA-381042|reactome:R-HSA-381183|reactome:R-HSA-9633012|reactome:R-HSA-9648895|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0061395"(positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|ensembl:ENST00000337304(transcript)|ensembl:ENST00000396680(transcript)|ensembl:ENST00000404241(transcript)|ensembl:ENST00000674568(transcript)|ensembl:ENST00000674835(transcript)|ensembl:ENST00000674920(transcript)|ensembl:ENST00000676346(transcript)|ensembl:ENST00000679776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|refseq:XP_016884296.1|dip:DIP-354N	psi-mi:"MI:0465"(dip)	-	crc64:3BBB7379DC3B0D07|comment:"No Uniprot Update and Caution  removed \" The protein could not be merged with EBI-12907955 because of some conflicts with the protein sequence (features which cannot be shifted).\" -EBI-12907955 no longer exists."	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/06	2017/08/10	rogid:4OpideXaQoVFi+x4P6iN5PG6RKY9606	rogid:2UolKWXxKFddysaOo70/U/1pI5k9606	rigid:sewfFecpJeBl5XwqFygdH/uDywA	false	his tag:n-n	sufficient binding region:277-351|flag tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P18847	uniprotkb:P18848	intact:EBI-712767|ensembl:ENSP00000344352|ensembl:ENSP00000355954|uniprotkb:Q5VTZ2|uniprotkb:Q6ICQ9|uniprotkb:Q7Z566|uniprotkb:Q8WYM6	intact:EBI-492498|uniprotkb:Q9UH31|ensembl:ENSP00000336790|ensembl:ENSP00000379912|ensembl:ENSP00000501783|ensembl:ENSP00000501863|ensembl:ENSP00000502400|ensembl:ENSP00000502610|ensembl:ENSP00000505360|ensembl:ENSP00000384587|intact:EBI-740263|uniprotkb:Q96AQ3	psi-mi:atf3_human(display_long)|uniprotkb:Activating transcription factor 3(gene name synonym)|uniprotkb:ATF3(gene name)|psi-mi:ATF3(display_short)	psi-mi:atf4_human(display_long)|uniprotkb:Activating transcription factor 4(gene name synonym)|uniprotkb:CREB2(gene name synonym)|uniprotkb:ATF4(gene name)|psi-mi:ATF4(display_short)|uniprotkb:TXREB(gene name synonym)|uniprotkb:Cyclic AMP-responsive element-binding protein 2(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 67(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wang et al. (2009)	pubmed:19164757|doi:10.1073/pnas.0807611106|imex:IM-14575	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15752984|imex:IM-14575-3|dip:DIP-103518E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162772(gene)|ensembl:ENST00000341491(transcript)|ensembl:ENST00000366987(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061394"(regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1903984"(positive regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029812|mint:P18847|reactome:R-HSA-380994|reactome:R-HSA-9633012|reactome:R-HSA-9648895|refseq:NP_001025458.1|refseq:NP_001665.1|refseq:XP_011507881.1|refseq:NP_001035709.1|refseq:NP_001193413.2|refseq:NP_001193415.1|refseq:NP_001193417.2|refseq:XP_005273203.1|dip:DIP-344N	refseq:NP_001666.2|refseq:NP_877962.1|ensembl:ENSG00000128272(gene)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0070982"(L-asparagine metabolic process)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140467"(integrated stress response signaling)|go:"GO:0140468"(HRI-mediated signaling)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990037"(Lewy body core)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990589"(ATF4-CREB1 transcription factor complex)|go:"GO:1990590"(ATF1-ATF4 transcription factor complex)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029811|mint:P18848|rcsb pdb:1CI6|reactome:R-HSA-380994|reactome:R-HSA-381042|reactome:R-HSA-381183|reactome:R-HSA-9633012|reactome:R-HSA-9648895|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0061395"(positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|ensembl:ENST00000337304(transcript)|ensembl:ENST00000396680(transcript)|ensembl:ENST00000404241(transcript)|ensembl:ENST00000674568(transcript)|ensembl:ENST00000674835(transcript)|ensembl:ENST00000674920(transcript)|ensembl:ENST00000676346(transcript)|ensembl:ENST00000679776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|refseq:XP_016884296.1|dip:DIP-354N	psi-mi:"MI:0465"(dip)	-	crc64:3BBB7379DC3B0D07|comment:"No Uniprot Update and Caution  removed \" The protein could not be merged with EBI-12907955 because of some conflicts with the protein sequence (features which cannot be shifted).\" -EBI-12907955 no longer exists."	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/06	2017/08/10	rogid:4OpideXaQoVFi+x4P6iN5PG6RKY9606	rogid:2UolKWXxKFddysaOo70/U/1pI5k9606	rigid:sewfFecpJeBl5XwqFygdH/uDywA	false	flag tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P18847	uniprotkb:P18848	intact:EBI-712767|ensembl:ENSP00000344352|ensembl:ENSP00000355954|uniprotkb:Q5VTZ2|uniprotkb:Q6ICQ9|uniprotkb:Q7Z566|uniprotkb:Q8WYM6	intact:EBI-492498|uniprotkb:Q9UH31|ensembl:ENSP00000336790|ensembl:ENSP00000379912|ensembl:ENSP00000501783|ensembl:ENSP00000501863|ensembl:ENSP00000502400|ensembl:ENSP00000502610|ensembl:ENSP00000505360|ensembl:ENSP00000384587|intact:EBI-740263|uniprotkb:Q96AQ3	psi-mi:atf3_human(display_long)|uniprotkb:Activating transcription factor 3(gene name synonym)|uniprotkb:ATF3(gene name)|psi-mi:ATF3(display_short)	psi-mi:atf4_human(display_long)|uniprotkb:Activating transcription factor 4(gene name synonym)|uniprotkb:CREB2(gene name synonym)|uniprotkb:ATF4(gene name)|psi-mi:ATF4(display_short)|uniprotkb:TXREB(gene name synonym)|uniprotkb:Cyclic AMP-responsive element-binding protein 2(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 67(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wang et al. (2009)	pubmed:19164757|doi:10.1073/pnas.0807611106|imex:IM-14575	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15753003|imex:IM-14575-4|dip:DIP-103518E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162772(gene)|ensembl:ENST00000341491(transcript)|ensembl:ENST00000366987(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061394"(regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1903984"(positive regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029812|mint:P18847|reactome:R-HSA-380994|reactome:R-HSA-9633012|reactome:R-HSA-9648895|refseq:NP_001025458.1|refseq:NP_001665.1|refseq:XP_011507881.1|refseq:NP_001035709.1|refseq:NP_001193413.2|refseq:NP_001193415.1|refseq:NP_001193417.2|refseq:XP_005273203.1|dip:DIP-344N	refseq:NP_001666.2|refseq:NP_877962.1|ensembl:ENSG00000128272(gene)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0070982"(L-asparagine metabolic process)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140467"(integrated stress response signaling)|go:"GO:0140468"(HRI-mediated signaling)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990037"(Lewy body core)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990589"(ATF4-CREB1 transcription factor complex)|go:"GO:1990590"(ATF1-ATF4 transcription factor complex)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029811|mint:P18848|rcsb pdb:1CI6|reactome:R-HSA-380994|reactome:R-HSA-381042|reactome:R-HSA-381183|reactome:R-HSA-9633012|reactome:R-HSA-9648895|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0061395"(positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|ensembl:ENST00000337304(transcript)|ensembl:ENST00000396680(transcript)|ensembl:ENST00000404241(transcript)|ensembl:ENST00000674568(transcript)|ensembl:ENST00000674835(transcript)|ensembl:ENST00000674920(transcript)|ensembl:ENST00000676346(transcript)|ensembl:ENST00000679776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|refseq:XP_016884296.1|dip:DIP-354N	psi-mi:"MI:0465"(dip)	-	crc64:3BBB7379DC3B0D07|comment:"No Uniprot Update and Caution  removed \" The protein could not be merged with EBI-12907955 because of some conflicts with the protein sequence (features which cannot be shifted).\" -EBI-12907955 no longer exists."	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:4OpideXaQoVFi+x4P6iN5PG6RKY9606	rogid:2UolKWXxKFddysaOo70/U/1pI5k9606	rigid:sewfFecpJeBl5XwqFygdH/uDywA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P18847	uniprotkb:P18848	intact:EBI-712767|ensembl:ENSP00000344352|ensembl:ENSP00000355954|uniprotkb:Q5VTZ2|uniprotkb:Q6ICQ9|uniprotkb:Q7Z566|uniprotkb:Q8WYM6	intact:EBI-492498|uniprotkb:Q9UH31|ensembl:ENSP00000336790|ensembl:ENSP00000379912|ensembl:ENSP00000501783|ensembl:ENSP00000501863|ensembl:ENSP00000502400|ensembl:ENSP00000502610|ensembl:ENSP00000505360|ensembl:ENSP00000384587|intact:EBI-740263|uniprotkb:Q96AQ3	psi-mi:atf3_human(display_long)|uniprotkb:Activating transcription factor 3(gene name synonym)|uniprotkb:ATF3(gene name)|psi-mi:ATF3(display_short)	psi-mi:atf4_human(display_long)|uniprotkb:Activating transcription factor 4(gene name synonym)|uniprotkb:CREB2(gene name synonym)|uniprotkb:ATF4(gene name)|psi-mi:ATF4(display_short)|uniprotkb:TXREB(gene name synonym)|uniprotkb:Cyclic AMP-responsive element-binding protein 2(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 67(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wang et al. (2009)	pubmed:19164757|doi:10.1073/pnas.0807611106|imex:IM-14575	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15752963|imex:IM-14575-2|dip:DIP-103518E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162772(gene)|ensembl:ENST00000341491(transcript)|ensembl:ENST00000366987(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061394"(regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1903984"(positive regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029812|mint:P18847|reactome:R-HSA-380994|reactome:R-HSA-9633012|reactome:R-HSA-9648895|refseq:NP_001025458.1|refseq:NP_001665.1|refseq:XP_011507881.1|refseq:NP_001035709.1|refseq:NP_001193413.2|refseq:NP_001193415.1|refseq:NP_001193417.2|refseq:XP_005273203.1|dip:DIP-344N	refseq:NP_001666.2|refseq:NP_877962.1|ensembl:ENSG00000128272(gene)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0070982"(L-asparagine metabolic process)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140467"(integrated stress response signaling)|go:"GO:0140468"(HRI-mediated signaling)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990037"(Lewy body core)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990589"(ATF4-CREB1 transcription factor complex)|go:"GO:1990590"(ATF1-ATF4 transcription factor complex)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029811|mint:P18848|rcsb pdb:1CI6|reactome:R-HSA-380994|reactome:R-HSA-381042|reactome:R-HSA-381183|reactome:R-HSA-9633012|reactome:R-HSA-9648895|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0061395"(positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|ensembl:ENST00000337304(transcript)|ensembl:ENST00000396680(transcript)|ensembl:ENST00000404241(transcript)|ensembl:ENST00000674568(transcript)|ensembl:ENST00000674835(transcript)|ensembl:ENST00000674920(transcript)|ensembl:ENST00000676346(transcript)|ensembl:ENST00000679776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|refseq:XP_016884296.1|dip:DIP-354N	psi-mi:"MI:0465"(dip)	-	crc64:3BBB7379DC3B0D07|comment:"No Uniprot Update and Caution  removed \" The protein could not be merged with EBI-12907955 because of some conflicts with the protein sequence (features which cannot be shifted).\" -EBI-12907955 no longer exists."	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/06	2017/08/10	rogid:4OpideXaQoVFi+x4P6iN5PG6RKY9606	rogid:2UolKWXxKFddysaOo70/U/1pI5k9606	rigid:sewfFecpJeBl5XwqFygdH/uDywA	false	-	flag tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P18847	uniprotkb:P18848	intact:EBI-712767|ensembl:ENSP00000344352|ensembl:ENSP00000355954|uniprotkb:Q5VTZ2|uniprotkb:Q6ICQ9|uniprotkb:Q7Z566|uniprotkb:Q8WYM6	intact:EBI-492498|uniprotkb:Q9UH31|ensembl:ENSP00000336790|ensembl:ENSP00000379912|ensembl:ENSP00000501783|ensembl:ENSP00000501863|ensembl:ENSP00000502400|ensembl:ENSP00000502610|ensembl:ENSP00000505360|ensembl:ENSP00000384587|intact:EBI-740263|uniprotkb:Q96AQ3	psi-mi:atf3_human(display_long)|uniprotkb:Activating transcription factor 3(gene name synonym)|uniprotkb:ATF3(gene name)|psi-mi:ATF3(display_short)	psi-mi:atf4_human(display_long)|uniprotkb:Activating transcription factor 4(gene name synonym)|uniprotkb:CREB2(gene name synonym)|uniprotkb:ATF4(gene name)|psi-mi:ATF4(display_short)|uniprotkb:TXREB(gene name synonym)|uniprotkb:Cyclic AMP-responsive element-binding protein 2(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 67(gene name synonym)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Wang et al. (2009)	pubmed:19164757|doi:10.1073/pnas.0807611106|imex:IM-14575	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15753020|imex:IM-14575-5|dip:DIP-103518E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162772(gene)|ensembl:ENST00000341491(transcript)|ensembl:ENST00000366987(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061394"(regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1903984"(positive regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029812|mint:P18847|reactome:R-HSA-380994|reactome:R-HSA-9633012|reactome:R-HSA-9648895|refseq:NP_001025458.1|refseq:NP_001665.1|refseq:XP_011507881.1|refseq:NP_001035709.1|refseq:NP_001193413.2|refseq:NP_001193415.1|refseq:NP_001193417.2|refseq:XP_005273203.1|dip:DIP-344N	refseq:NP_001666.2|refseq:NP_877962.1|ensembl:ENSG00000128272(gene)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0070982"(L-asparagine metabolic process)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140467"(integrated stress response signaling)|go:"GO:0140468"(HRI-mediated signaling)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990037"(Lewy body core)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990589"(ATF4-CREB1 transcription factor complex)|go:"GO:1990590"(ATF1-ATF4 transcription factor complex)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029811|mint:P18848|rcsb pdb:1CI6|reactome:R-HSA-380994|reactome:R-HSA-381042|reactome:R-HSA-381183|reactome:R-HSA-9633012|reactome:R-HSA-9648895|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0061395"(positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|ensembl:ENST00000337304(transcript)|ensembl:ENST00000396680(transcript)|ensembl:ENST00000404241(transcript)|ensembl:ENST00000674568(transcript)|ensembl:ENST00000674835(transcript)|ensembl:ENST00000674920(transcript)|ensembl:ENST00000676346(transcript)|ensembl:ENST00000679776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|refseq:XP_016884296.1|dip:DIP-354N	psi-mi:"MI:0465"(dip)	-	crc64:3BBB7379DC3B0D07|comment:"No Uniprot Update and Caution  removed \" The protein could not be merged with EBI-12907955 because of some conflicts with the protein sequence (features which cannot be shifted).\" -EBI-12907955 no longer exists."	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:4OpideXaQoVFi+x4P6iN5PG6RKY9606	rogid:2UolKWXxKFddysaOo70/U/1pI5k9606	rigid:sewfFecpJeBl5XwqFygdH/uDywA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)