#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P01901 uniprotkb:P07725 intact:EBI-1265227|ensembl:ENSMUSP00000025181 intact:EBI-15728591|ensembl:ENSRNOP00000009516 psi-mi:ha1b_mouse(display_long)|uniprotkb:H2-K1(gene name)|psi-mi:H2-K1(display_short)|uniprotkb:H2-K(gene name synonym) psi-mi:cd8a_rat(display_long)|uniprotkb:Cd8a(gene name)|psi-mi:Cd8a(display_short)|uniprotkb:CD8 antigen 32 kDa chain(gene name synonym)|uniprotkb:OX-8 membrane antigen(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Endo et al. (2008) pubmed:18787130|doi:10.1073/pnas.0804571105|imex:IM-22469 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15728622|imex:IM-22469-1|dip:DIP-196220E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001892.2|dip:DIP-6189N|ensembl:ENSMUSG00000061232(gene)|ensembl:ENSMUST00000025181(transcript)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002476"(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:"GO:0002485"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030881"(beta-2-microglobulin binding)|go:"GO:0042277"(peptide binding)|go:"GO:0042590"(antigen processing and presentation of exogenous peptide antigen via MHC class I)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042610"(CD8 receptor binding)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046977"(TAP binding)|go:"GO:0048839"(inner ear development)|go:"GO:0062061"(TAP complex binding)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|mint:P01901|rcsb pdb:1BQH|rcsb pdb:1FO0|rcsb pdb:1FZJ|rcsb pdb:1FZK|rcsb pdb:1FZM|rcsb pdb:1FZO|rcsb pdb:1G6R|rcsb pdb:1G7P|rcsb pdb:1G7Q|rcsb pdb:1KBG|rcsb pdb:1KJ2|rcsb pdb:1KJ3|rcsb pdb:1KPU|rcsb pdb:1KPV|rcsb pdb:1LEG|rcsb pdb:1LEK|rcsb pdb:1LK2|rcsb pdb:1MWA|rcsb pdb:1N59|rcsb pdb:1NAM|rcsb pdb:1NAN|rcsb pdb:1OSZ|rcsb pdb:1P1Z|rcsb pdb:1P4L|rcsb pdb:1RJY|rcsb pdb:1RJZ|rcsb pdb:1RK0|rcsb pdb:1RK1|rcsb pdb:1S7Q|rcsb pdb:1S7R|rcsb pdb:1S7S|rcsb pdb:1S7T|rcsb pdb:1T0M|rcsb pdb:1T0N|rcsb pdb:1VAC|rcsb pdb:1VAD|rcsb pdb:1WBZ|rcsb pdb:2CKB|rcsb pdb:2CLV|rcsb pdb:2CLZ|rcsb pdb:2FO4|rcsb pdb:2MHA|rcsb pdb:2OL3|rcsb pdb:2QRI|rcsb pdb:2QRS|rcsb pdb:2QRT|rcsb pdb:2VAA|rcsb pdb:2VAB|rcsb pdb:2ZSV|rcsb pdb:2ZSW|rcsb pdb:3C8K|rcsb pdb:3CVH|rcsb pdb:3P4M|rcsb pdb:3P4N|rcsb pdb:3P4O|rcsb pdb:3P9L|rcsb pdb:3P9M|rcsb pdb:3PAB|rcsb pdb:3RGV|rcsb pdb:3ROL|rcsb pdb:3ROO|rcsb pdb:3TID|rcsb pdb:3TIE|rcsb pdb:4HKJ|rcsb pdb:4HS3|rcsb pdb:4PG9|rcsb pdb:4PGB|rcsb pdb:4PGC|rcsb pdb:4PGD|rcsb pdb:4PGE|rcsb pdb:4PV8|rcsb pdb:4PV9|rcsb pdb:5OQF|rcsb pdb:5OQG|rcsb pdb:5OQH|rcsb pdb:5OQI|rcsb pdb:6GB6|rcsb pdb:6JQ2|rcsb pdb:6JQ3|rcsb pdb:6WL2|rcsb pdb:6WL3|rcsb pdb:6WL4|rcsb pdb:7JI2|reactome:R-MMU-1236974|reactome:R-MMU-1236977|reactome:R-MMU-198933|reactome:R-MMU-6798695|reactome:R-MMU-983170 ensembl:ENSRNOG00000007178(gene)|ensembl:ENSRNOT00000009515(transcript)|go:"GO:0002456"(T cell mediated immunity)|go:"GO:0006954"(inflammatory response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023024"(MHC class I protein complex binding)|go:"GO:0042110"(T cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045065"(cytotoxic T cell differentiation)|go:"GO:0050850"(positive regulation of calcium-mediated signaling)|go:"GO:0051607"(defense response to virus)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015468(CD8 alpha chain)|interpro:IPR036179|reactome:R-RNO-198933|dip:DIP-60779N|refseq:NP_113726.1|refseq:XP_006236692.1|refseq:XP_008761198.1|rgd:2316 psi-mi:"MI:0465"(dip) - crc64:ADFAC54E4C99C1BE full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:dsETQ24P6uiTklK2dPUh3rAmym010090 rogid:ZaJlIAaZiu1/s2ootrjv0vGLGVA10116 rigid:GUeupf/IIL7kR/W+rqwQfR5kVss false - sufficient binding region:1-151 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P97484 uniprotkb:P01901 intact:EBI-15728641|ensembl:ENSMUSP00000077546 intact:EBI-1265227|ensembl:ENSMUSP00000025181 psi-mi:lirb3_mouse(display_long)|uniprotkb:Lilrb3(gene name)|psi-mi:Lilrb3(display_short)|uniprotkb:Pirb(gene name synonym)|uniprotkb:Cell-surface glycoprotein p91(gene name synonym)|uniprotkb:Paired immunoglobulin-like receptor B(gene name synonym) psi-mi:ha1b_mouse(display_long)|uniprotkb:H2-K1(gene name)|psi-mi:H2-K1(display_short)|uniprotkb:H2-K(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Endo et al. (2008) pubmed:18787130|doi:10.1073/pnas.0804571105|imex:IM-22469 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15728667|imex:IM-22469-2|dip:DIP-196221E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000058818(gene)|ensembl:ENSMUST00000078451(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0005886"(plasma membrane)|go:"GO:0007611"(learning or memory)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|refseq:NP_035225.2|dip:DIP-59889N refseq:NP_001001892.2|dip:DIP-6189N|ensembl:ENSMUSG00000061232(gene)|ensembl:ENSMUST00000025181(transcript)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002476"(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:"GO:0002485"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030881"(beta-2-microglobulin binding)|go:"GO:0042277"(peptide binding)|go:"GO:0042590"(antigen processing and presentation of exogenous peptide antigen via MHC class I)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042610"(CD8 receptor binding)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046977"(TAP binding)|go:"GO:0048839"(inner ear development)|go:"GO:0062061"(TAP complex binding)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|mint:P01901|rcsb pdb:1BQH|rcsb pdb:1FO0|rcsb pdb:1FZJ|rcsb pdb:1FZK|rcsb pdb:1FZM|rcsb pdb:1FZO|rcsb pdb:1G6R|rcsb pdb:1G7P|rcsb pdb:1G7Q|rcsb pdb:1KBG|rcsb pdb:1KJ2|rcsb pdb:1KJ3|rcsb pdb:1KPU|rcsb pdb:1KPV|rcsb pdb:1LEG|rcsb pdb:1LEK|rcsb pdb:1LK2|rcsb pdb:1MWA|rcsb pdb:1N59|rcsb pdb:1NAM|rcsb pdb:1NAN|rcsb pdb:1OSZ|rcsb pdb:1P1Z|rcsb pdb:1P4L|rcsb pdb:1RJY|rcsb pdb:1RJZ|rcsb pdb:1RK0|rcsb pdb:1RK1|rcsb pdb:1S7Q|rcsb pdb:1S7R|rcsb pdb:1S7S|rcsb pdb:1S7T|rcsb pdb:1T0M|rcsb pdb:1T0N|rcsb pdb:1VAC|rcsb pdb:1VAD|rcsb pdb:1WBZ|rcsb pdb:2CKB|rcsb pdb:2CLV|rcsb pdb:2CLZ|rcsb pdb:2FO4|rcsb pdb:2MHA|rcsb pdb:2OL3|rcsb pdb:2QRI|rcsb pdb:2QRS|rcsb pdb:2QRT|rcsb pdb:2VAA|rcsb pdb:2VAB|rcsb pdb:2ZSV|rcsb pdb:2ZSW|rcsb pdb:3C8K|rcsb pdb:3CVH|rcsb pdb:3P4M|rcsb pdb:3P4N|rcsb pdb:3P4O|rcsb pdb:3P9L|rcsb pdb:3P9M|rcsb pdb:3PAB|rcsb pdb:3RGV|rcsb pdb:3ROL|rcsb pdb:3ROO|rcsb pdb:3TID|rcsb pdb:3TIE|rcsb pdb:4HKJ|rcsb pdb:4HS3|rcsb pdb:4PG9|rcsb pdb:4PGB|rcsb pdb:4PGC|rcsb pdb:4PGD|rcsb pdb:4PGE|rcsb pdb:4PV8|rcsb pdb:4PV9|rcsb pdb:5OQF|rcsb pdb:5OQG|rcsb pdb:5OQH|rcsb pdb:5OQI|rcsb pdb:6GB6|rcsb pdb:6JQ2|rcsb pdb:6JQ3|rcsb pdb:6WL2|rcsb pdb:6WL3|rcsb pdb:6WL4|rcsb pdb:7JI2|reactome:R-MMU-1236974|reactome:R-MMU-1236977|reactome:R-MMU-198933|reactome:R-MMU-6798695|reactome:R-MMU-983170 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:LvDmslSnZmh1nZvksx5uODaSLd010090 rogid:dsETQ24P6uiTklK2dPUh3rAmym010090 rigid:6L4JQco9PcEZR2diAsQ2/9QZX68 false sufficient binding region:1-618 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)