#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9VK21 uniprotkb:Q9V475 intact:EBI-147243|ensemblmetazoa:FBpp0080063 intact:EBI-109873|ensemblmetazoa:FBpp0291366|ensemblmetazoa:FBpp0291367|ensemblmetazoa:FBpp0291368 psi-mi:q9vk21_drome(display_long)|uniprotkb:Ipp(gene name)|psi-mi:Ipp(display_short)|uniprotkb:Dmel\CG9426(gene name synonym)|uniprotkb:CG9426(orf name)|uniprotkb:Dmel_CG9426(orf name) psi-mi:q9v475_drome(display_long)|uniprotkb:CG11861(gene name synonym)|uniprotkb:CG31829(gene name synonym)|uniprotkb:Cul3(gene name)|psi-mi:Cul3(display_short)|uniprotkb:Cul-3(gene name synonym)|uniprotkb:cul-3(gene name synonym)|uniprotkb:gft(gene name synonym)|uniprotkb:CG42616(orf name)|uniprotkb:"BG:DS07851.2"(gene name synonym)|uniprotkb:CUL-3(gene name synonym)|uniprotkb:CUL3(gene name synonym)|uniprotkb:Cullin3(gene name synonym)|uniprotkb:DMcul-3(gene name synonym)|uniprotkb:Dmel\CG42616(gene name synonym)|uniprotkb:br34(gene name synonym)|uniprotkb:cul3(gene name synonym)|uniprotkb:dCul-3(gene name synonym)|uniprotkb:dCul3(gene name synonym)|uniprotkb:guftagu(gene name synonym)|uniprotkb:"l(2)06430"(gene name synonym)|uniprotkb:"l(2)35Cd"(gene name synonym)|uniprotkb:"l(2)br34"(gene name synonym)|uniprotkb:l35Cd(gene name synonym)|uniprotkb:mds(gene name synonym)|uniprotkb:Dmel_CG42616(orf name) psi-mi:"MI:0018"(two hybrid) Arama et al. (2007) pubmed:17880263|doi:10.1371/journal.pbio.0050251|imex:IM-8840 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15659242|imex:IM-8840-3|dip:DIP-58964E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_609616.1|flybase:FBgn0032485|dip:DIP-29552N|ensemblmetazoa:FBgn0032485(gene)|ensemblmetazoa:FBtr0080484(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0016567"(protein ubiquitination)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030104 refseq:NP_523573.1|refseq:NP_723907.1|refseq:NP_723908.2|flybase:FBgn0261268|dip:DIP-29549N|ensemblmetazoa:FBgn0261268(gene)|ensemblmetazoa:FBtr0302156(transcript)|ensemblmetazoa:FBtr0302157(transcript)|ensemblmetazoa:FBtr0302158(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007291"(sperm individualization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007423"(sensory organ development)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030431"(sleep)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0048813"(dendrite morphogenesis)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|reactome:R-DME-216167 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:oxy/YksXXIG45x+oufiCgXhIbDo7227 rogid:FdSkVuXrUqWZ/sUgajntxvW8pd07227 rigid:CaEisY0+zMy/qI9yktZghg5xT0c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9VFP2-2 uniprotkb:Q9V475 intact:EBI-15659276|ensemblmetazoa:FBpp0290847 intact:EBI-109873|ensemblmetazoa:FBpp0291366|ensemblmetazoa:FBpp0291367|ensemblmetazoa:FBpp0291368 psi-mi:q9vfp2-2(display_long)|uniprotkb:HIB(gene name synonym)|uniprotkb:Hh-induced MATH and BTB domain-containing protein(gene name synonym)|uniprotkb:CG12537(orf name)|uniprotkb:B(isoform synonym)|uniprotkb:rdx(gene name)|psi-mi:rdx(display_short) psi-mi:q9v475_drome(display_long)|uniprotkb:CG11861(gene name synonym)|uniprotkb:CG31829(gene name synonym)|uniprotkb:Cul3(gene name)|psi-mi:Cul3(display_short)|uniprotkb:Cul-3(gene name synonym)|uniprotkb:cul-3(gene name synonym)|uniprotkb:gft(gene name synonym)|uniprotkb:CG42616(orf name)|uniprotkb:"BG:DS07851.2"(gene name synonym)|uniprotkb:CUL-3(gene name synonym)|uniprotkb:CUL3(gene name synonym)|uniprotkb:Cullin3(gene name synonym)|uniprotkb:DMcul-3(gene name synonym)|uniprotkb:Dmel\CG42616(gene name synonym)|uniprotkb:br34(gene name synonym)|uniprotkb:cul3(gene name synonym)|uniprotkb:dCul-3(gene name synonym)|uniprotkb:dCul3(gene name synonym)|uniprotkb:guftagu(gene name synonym)|uniprotkb:"l(2)06430"(gene name synonym)|uniprotkb:"l(2)35Cd"(gene name synonym)|uniprotkb:"l(2)br34"(gene name synonym)|uniprotkb:l35Cd(gene name synonym)|uniprotkb:mds(gene name synonym)|uniprotkb:Dmel_CG42616(orf name) psi-mi:"MI:0018"(two hybrid) Arama et al. (2007) pubmed:17880263|doi:10.1371/journal.pbio.0050251|imex:IM-8840 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15659286|imex:IM-8840-7|dip:DIP-58963E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-132658(isoform-parent)|ensemblmetazoa:FBgn0264493(gene)|ensemblmetazoa:FBtr0301633(transcript) refseq:NP_523573.1|refseq:NP_723907.1|refseq:NP_723908.2|flybase:FBgn0261268|dip:DIP-29549N|ensemblmetazoa:FBgn0261268(gene)|ensemblmetazoa:FBtr0302156(transcript)|ensemblmetazoa:FBtr0302157(transcript)|ensemblmetazoa:FBtr0302158(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007291"(sperm individualization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007423"(sensory organ development)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030431"(sleep)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0048813"(dendrite morphogenesis)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|reactome:R-DME-216167 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:wK8MgTf5GOHgmS5XgIMphs8z+oE7227 rogid:FdSkVuXrUqWZ/sUgajntxvW8pd07227 rigid:7G8I7mb+8/6F4bSRcTK8ezJqOUw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9VK21 uniprotkb:Q9V475 intact:EBI-147243|ensemblmetazoa:FBpp0080063 intact:EBI-109873|ensemblmetazoa:FBpp0291366|ensemblmetazoa:FBpp0291367|ensemblmetazoa:FBpp0291368 psi-mi:q9vk21_drome(display_long)|uniprotkb:Ipp(gene name)|psi-mi:Ipp(display_short)|uniprotkb:Dmel\CG9426(gene name synonym)|uniprotkb:CG9426(orf name)|uniprotkb:Dmel_CG9426(orf name) psi-mi:q9v475_drome(display_long)|uniprotkb:CG11861(gene name synonym)|uniprotkb:CG31829(gene name synonym)|uniprotkb:Cul3(gene name)|psi-mi:Cul3(display_short)|uniprotkb:Cul-3(gene name synonym)|uniprotkb:cul-3(gene name synonym)|uniprotkb:gft(gene name synonym)|uniprotkb:CG42616(orf name)|uniprotkb:"BG:DS07851.2"(gene name synonym)|uniprotkb:CUL-3(gene name synonym)|uniprotkb:CUL3(gene name synonym)|uniprotkb:Cullin3(gene name synonym)|uniprotkb:DMcul-3(gene name synonym)|uniprotkb:Dmel\CG42616(gene name synonym)|uniprotkb:br34(gene name synonym)|uniprotkb:cul3(gene name synonym)|uniprotkb:dCul-3(gene name synonym)|uniprotkb:dCul3(gene name synonym)|uniprotkb:guftagu(gene name synonym)|uniprotkb:"l(2)06430"(gene name synonym)|uniprotkb:"l(2)35Cd"(gene name synonym)|uniprotkb:"l(2)br34"(gene name synonym)|uniprotkb:l35Cd(gene name synonym)|uniprotkb:mds(gene name synonym)|uniprotkb:Dmel_CG42616(orf name) psi-mi:"MI:0018"(two hybrid) Arama et al. (2007) pubmed:17880263|doi:10.1371/journal.pbio.0050251|imex:IM-8840 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15659259|imex:IM-8840-6|dip:DIP-58964E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_609616.1|flybase:FBgn0032485|dip:DIP-29552N|ensemblmetazoa:FBgn0032485(gene)|ensemblmetazoa:FBtr0080484(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0016567"(protein ubiquitination)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030104 refseq:NP_523573.1|refseq:NP_723907.1|refseq:NP_723908.2|flybase:FBgn0261268|dip:DIP-29549N|ensemblmetazoa:FBgn0261268(gene)|ensemblmetazoa:FBtr0302156(transcript)|ensemblmetazoa:FBtr0302157(transcript)|ensemblmetazoa:FBtr0302158(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007291"(sperm individualization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007423"(sensory organ development)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030431"(sleep)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0048813"(dendrite morphogenesis)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|reactome:R-DME-216167 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:oxy/YksXXIG45x+oufiCgXhIbDo7227 rogid:FdSkVuXrUqWZ/sUgajntxvW8pd07227 rigid:CaEisY0+zMy/qI9yktZghg5xT0c false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6GKZ1 uniprotkb:Q9VH01 intact:EBI-15659303|ensemblmetazoa:FBpp0112408|ensemblmetazoa:FBpp0112409|uniprotkb:Q500X7|uniprotkb:Q7PLC2 intact:EBI-2509194|ensemblmetazoa:FBpp0081717|uniprotkb:Q8MUM9|intact:EBI-3421368 psi-mi:q6gkz1_drome(display_long)|uniprotkb:klhl10(gene name)|psi-mi:klhl10(display_short)|uniprotkb:Dmel\CG12423(gene name synonym)|uniprotkb:anon-WO0140519.152(gene name synonym)|uniprotkb:CG12423(orf name)|uniprotkb:Dmel_CG12423(orf name)|uniprotkb:Klhl10(gene name synonym) psi-mi:q9vh01_drome(display_long)|uniprotkb:Bruce(gene name)|psi-mi:Bruce(display_short)|uniprotkb:CG6303(orf name)|uniprotkb:BRUCE(gene name synonym)|uniprotkb:Dmel\CG6303(gene name synonym)|uniprotkb:bruce(gene name synonym)|uniprotkb:dBRUCE(gene name synonym)|uniprotkb:dBruce(gene name synonym)|uniprotkb:dbruce(gene name synonym)|uniprotkb:mod86(gene name synonym)|uniprotkb:Dmel_CG6303(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Arama et al. (2007) pubmed:17880263|doi:10.1371/journal.pbio.0050251|imex:IM-8840 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15659379|imex:IM-8840-4|dip:DIP-58962E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0040038(gene)|ensemblmetazoa:FBtr0113685(transcript)|ensemblmetazoa:FBtr0113686(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007291"(sperm individualization)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|refseq:NP_001015100.2|refseq:NP_001015101.2|flybase:FBgn0040038|dip:DIP-29551N ensemblmetazoa:FBgn0266717(gene)|ensemblmetazoa:FBtr0082239(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007286"(spermatid development)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012501"(programmed cell death)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045849"(negative regulation of nurse cell apoptotic process)|go:"GO:0048477"(oogenesis)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR022103|refseq:NP_649995.2|flybase:FBgn0266717|dip:DIP-29548N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:eLtokUp/v7ND4paAiwyuUGU8m6E7227 rogid:xWuV06zMJ3+3XzdVUp9D0ldzzXk7227 rigid:VTzcgdJ9NXFBkxi/chpoJowdHHk false protein a tag:n-n sufficient binding region:1-378|ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9VFP2-2 uniprotkb:Q9V475 intact:EBI-15659276|ensemblmetazoa:FBpp0290847 intact:EBI-109873|ensemblmetazoa:FBpp0291366|ensemblmetazoa:FBpp0291367|ensemblmetazoa:FBpp0291368 psi-mi:q9vfp2-2(display_long)|uniprotkb:HIB(gene name synonym)|uniprotkb:Hh-induced MATH and BTB domain-containing protein(gene name synonym)|uniprotkb:CG12537(orf name)|uniprotkb:B(isoform synonym)|uniprotkb:rdx(gene name)|psi-mi:rdx(display_short) psi-mi:q9v475_drome(display_long)|uniprotkb:CG11861(gene name synonym)|uniprotkb:CG31829(gene name synonym)|uniprotkb:Cul3(gene name)|psi-mi:Cul3(display_short)|uniprotkb:Cul-3(gene name synonym)|uniprotkb:cul-3(gene name synonym)|uniprotkb:gft(gene name synonym)|uniprotkb:CG42616(orf name)|uniprotkb:"BG:DS07851.2"(gene name synonym)|uniprotkb:CUL-3(gene name synonym)|uniprotkb:CUL3(gene name synonym)|uniprotkb:Cullin3(gene name synonym)|uniprotkb:DMcul-3(gene name synonym)|uniprotkb:Dmel\CG42616(gene name synonym)|uniprotkb:br34(gene name synonym)|uniprotkb:cul3(gene name synonym)|uniprotkb:dCul-3(gene name synonym)|uniprotkb:dCul3(gene name synonym)|uniprotkb:guftagu(gene name synonym)|uniprotkb:"l(2)06430"(gene name synonym)|uniprotkb:"l(2)35Cd"(gene name synonym)|uniprotkb:"l(2)br34"(gene name synonym)|uniprotkb:l35Cd(gene name synonym)|uniprotkb:mds(gene name synonym)|uniprotkb:Dmel_CG42616(orf name) psi-mi:"MI:0018"(two hybrid) Arama et al. (2007) pubmed:17880263|doi:10.1371/journal.pbio.0050251|imex:IM-8840 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15659362|imex:IM-8840-1|dip:DIP-58963E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-132658(isoform-parent)|ensemblmetazoa:FBgn0264493(gene)|ensemblmetazoa:FBtr0301633(transcript) refseq:NP_523573.1|refseq:NP_723907.1|refseq:NP_723908.2|flybase:FBgn0261268|dip:DIP-29549N|ensemblmetazoa:FBgn0261268(gene)|ensemblmetazoa:FBtr0302156(transcript)|ensemblmetazoa:FBtr0302157(transcript)|ensemblmetazoa:FBtr0302158(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007291"(sperm individualization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007423"(sensory organ development)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030431"(sleep)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0048813"(dendrite morphogenesis)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|reactome:R-DME-216167 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:wK8MgTf5GOHgmS5XgIMphs8z+oE7227 rogid:FdSkVuXrUqWZ/sUgajntxvW8pd07227 rigid:7G8I7mb+8/6F4bSRcTK8ezJqOUw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6GKZ1 uniprotkb:Q9V475 intact:EBI-15659303|ensemblmetazoa:FBpp0112408|ensemblmetazoa:FBpp0112409|uniprotkb:Q500X7|uniprotkb:Q7PLC2 intact:EBI-109873|ensemblmetazoa:FBpp0291366|ensemblmetazoa:FBpp0291367|ensemblmetazoa:FBpp0291368 psi-mi:q6gkz1_drome(display_long)|uniprotkb:klhl10(gene name)|psi-mi:klhl10(display_short)|uniprotkb:Dmel\CG12423(gene name synonym)|uniprotkb:anon-WO0140519.152(gene name synonym)|uniprotkb:CG12423(orf name)|uniprotkb:Dmel_CG12423(orf name)|uniprotkb:Klhl10(gene name synonym) psi-mi:q9v475_drome(display_long)|uniprotkb:CG11861(gene name synonym)|uniprotkb:CG31829(gene name synonym)|uniprotkb:Cul3(gene name)|psi-mi:Cul3(display_short)|uniprotkb:Cul-3(gene name synonym)|uniprotkb:cul-3(gene name synonym)|uniprotkb:gft(gene name synonym)|uniprotkb:CG42616(orf name)|uniprotkb:"BG:DS07851.2"(gene name synonym)|uniprotkb:CUL-3(gene name synonym)|uniprotkb:CUL3(gene name synonym)|uniprotkb:Cullin3(gene name synonym)|uniprotkb:DMcul-3(gene name synonym)|uniprotkb:Dmel\CG42616(gene name synonym)|uniprotkb:br34(gene name synonym)|uniprotkb:cul3(gene name synonym)|uniprotkb:dCul-3(gene name synonym)|uniprotkb:dCul3(gene name synonym)|uniprotkb:guftagu(gene name synonym)|uniprotkb:"l(2)06430"(gene name synonym)|uniprotkb:"l(2)35Cd"(gene name synonym)|uniprotkb:"l(2)br34"(gene name synonym)|uniprotkb:l35Cd(gene name synonym)|uniprotkb:mds(gene name synonym)|uniprotkb:Dmel_CG42616(orf name) psi-mi:"MI:0018"(two hybrid) Arama et al. (2007) pubmed:17880263|doi:10.1371/journal.pbio.0050251|imex:IM-8840 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15659345|imex:IM-8840-5|dip:DIP-58965E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0040038(gene)|ensemblmetazoa:FBtr0113685(transcript)|ensemblmetazoa:FBtr0113686(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007291"(sperm individualization)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|refseq:NP_001015100.2|refseq:NP_001015101.2|flybase:FBgn0040038|dip:DIP-29551N refseq:NP_523573.1|refseq:NP_723907.1|refseq:NP_723908.2|flybase:FBgn0261268|dip:DIP-29549N|ensemblmetazoa:FBgn0261268(gene)|ensemblmetazoa:FBtr0302156(transcript)|ensemblmetazoa:FBtr0302157(transcript)|ensemblmetazoa:FBtr0302158(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007291"(sperm individualization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007423"(sensory organ development)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030431"(sleep)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0048813"(dendrite morphogenesis)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|reactome:R-DME-216167 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:eLtokUp/v7ND4paAiwyuUGU8m6E7227 rogid:FdSkVuXrUqWZ/sUgajntxvW8pd07227 rigid:Suf03loIFtuwpmtbXx/CFip8kjc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6GKZ1 uniprotkb:Q9V475 intact:EBI-15659303|ensemblmetazoa:FBpp0112408|ensemblmetazoa:FBpp0112409|uniprotkb:Q500X7|uniprotkb:Q7PLC2 intact:EBI-109873|ensemblmetazoa:FBpp0291366|ensemblmetazoa:FBpp0291367|ensemblmetazoa:FBpp0291368 psi-mi:q6gkz1_drome(display_long)|uniprotkb:klhl10(gene name)|psi-mi:klhl10(display_short)|uniprotkb:Dmel\CG12423(gene name synonym)|uniprotkb:anon-WO0140519.152(gene name synonym)|uniprotkb:CG12423(orf name)|uniprotkb:Dmel_CG12423(orf name)|uniprotkb:Klhl10(gene name synonym) psi-mi:q9v475_drome(display_long)|uniprotkb:CG11861(gene name synonym)|uniprotkb:CG31829(gene name synonym)|uniprotkb:Cul3(gene name)|psi-mi:Cul3(display_short)|uniprotkb:Cul-3(gene name synonym)|uniprotkb:cul-3(gene name synonym)|uniprotkb:gft(gene name synonym)|uniprotkb:CG42616(orf name)|uniprotkb:"BG:DS07851.2"(gene name synonym)|uniprotkb:CUL-3(gene name synonym)|uniprotkb:CUL3(gene name synonym)|uniprotkb:Cullin3(gene name synonym)|uniprotkb:DMcul-3(gene name synonym)|uniprotkb:Dmel\CG42616(gene name synonym)|uniprotkb:br34(gene name synonym)|uniprotkb:cul3(gene name synonym)|uniprotkb:dCul-3(gene name synonym)|uniprotkb:dCul3(gene name synonym)|uniprotkb:guftagu(gene name synonym)|uniprotkb:"l(2)06430"(gene name synonym)|uniprotkb:"l(2)35Cd"(gene name synonym)|uniprotkb:"l(2)br34"(gene name synonym)|uniprotkb:l35Cd(gene name synonym)|uniprotkb:mds(gene name synonym)|uniprotkb:Dmel_CG42616(orf name) psi-mi:"MI:0018"(two hybrid) Arama et al. (2007) pubmed:17880263|doi:10.1371/journal.pbio.0050251|imex:IM-8840 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15659328|imex:IM-8840-2|dip:DIP-58965E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0040038(gene)|ensemblmetazoa:FBtr0113685(transcript)|ensemblmetazoa:FBtr0113686(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007291"(sperm individualization)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|refseq:NP_001015100.2|refseq:NP_001015101.2|flybase:FBgn0040038|dip:DIP-29551N refseq:NP_523573.1|refseq:NP_723907.1|refseq:NP_723908.2|flybase:FBgn0261268|dip:DIP-29549N|ensemblmetazoa:FBgn0261268(gene)|ensemblmetazoa:FBtr0302156(transcript)|ensemblmetazoa:FBtr0302157(transcript)|ensemblmetazoa:FBtr0302158(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007291"(sperm individualization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007423"(sensory organ development)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030431"(sleep)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0048813"(dendrite morphogenesis)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|reactome:R-DME-216167 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:eLtokUp/v7ND4paAiwyuUGU8m6E7227 rogid:FdSkVuXrUqWZ/sUgajntxvW8pd07227 rigid:Suf03loIFtuwpmtbXx/CFip8kjc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6GKZ1 uniprotkb:Q9VH01 intact:EBI-15659303|ensemblmetazoa:FBpp0112408|ensemblmetazoa:FBpp0112409|uniprotkb:Q500X7|uniprotkb:Q7PLC2 intact:EBI-2509194|ensemblmetazoa:FBpp0081717|uniprotkb:Q8MUM9|intact:EBI-3421368 psi-mi:q6gkz1_drome(display_long)|uniprotkb:klhl10(gene name)|psi-mi:klhl10(display_short)|uniprotkb:Dmel\CG12423(gene name synonym)|uniprotkb:anon-WO0140519.152(gene name synonym)|uniprotkb:CG12423(orf name)|uniprotkb:Dmel_CG12423(orf name)|uniprotkb:Klhl10(gene name synonym) psi-mi:q9vh01_drome(display_long)|uniprotkb:Bruce(gene name)|psi-mi:Bruce(display_short)|uniprotkb:CG6303(orf name)|uniprotkb:BRUCE(gene name synonym)|uniprotkb:Dmel\CG6303(gene name synonym)|uniprotkb:bruce(gene name synonym)|uniprotkb:dBRUCE(gene name synonym)|uniprotkb:dBruce(gene name synonym)|uniprotkb:dbruce(gene name synonym)|uniprotkb:mod86(gene name synonym)|uniprotkb:Dmel_CG6303(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Arama et al. (2007) pubmed:17880263|doi:10.1371/journal.pbio.0050251|imex:IM-8840 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15659402|imex:IM-8840-8|dip:DIP-58962E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0040038(gene)|ensemblmetazoa:FBtr0113685(transcript)|ensemblmetazoa:FBtr0113686(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007291"(sperm individualization)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|refseq:NP_001015100.2|refseq:NP_001015101.2|flybase:FBgn0040038|dip:DIP-29551N ensemblmetazoa:FBgn0266717(gene)|ensemblmetazoa:FBtr0082239(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007286"(spermatid development)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012501"(programmed cell death)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045849"(negative regulation of nurse cell apoptotic process)|go:"GO:0048477"(oogenesis)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR022103|refseq:NP_649995.2|flybase:FBgn0266717|dip:DIP-29548N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:eLtokUp/v7ND4paAiwyuUGU8m6E7227 rogid:xWuV06zMJ3+3XzdVUp9D0ldzzXk7227 rigid:VTzcgdJ9NXFBkxi/chpoJowdHHk false protein a tag:n-n sufficient binding region:1-1622 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)