#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:A1YH68 uniprotkb:P46116 intact:EBI-10098044|ensemblbacteria:SUC45241|ensemblbacteria:SUC77857 intact:EBI-10098058 psi-mi:a1yh68_prost(display_long)|uniprotkb:tatA(gene name)|psi-mi:tatA(display_short)|uniprotkb:NCTC12257_03922(orf name) psi-mi:aara_prost(display_long)|uniprotkb:aarA(gene name)|psi-mi:aarA(display_short)|uniprotkb:Intramembrane serine protease(gene name synonym) psi-mi:"MI:0435"(protease assay) Stevenson et al. (2007) pubmed:17215357|doi:10.1073/pnas.0608140104|imex:IM-22498 taxid:588(prost)|taxid:588(Providencia stuartii) taxid:588(prost)|taxid:588(Providencia stuartii) psi-mi:"MI:0570"(protein cleavage) psi-mi:"MI:0465"(DIP) intact:EBI-15618464|imex:IM-22498-1|dip:DIP-196276E - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_004924718.1|ensemblbacteria:NCTC11800_03651(gene)|ensemblbacteria:NCTC12257_03922(gene)|ensemblbacteria:SUC45241(transcript)|ensemblbacteria:SUC77857(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0033281"(TAT protein transport complex)|go:"GO:0043953"(protein transport by the Tat complex)|interpro:IPR003369(Bacterial sec-independent translocation protein mttA/Hcf106)|interpro:IPR006312(Twin-arginine translocation protein TatA/E)|dip:DIP-60799N refseq:WP_004917931.1|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR022764|interpro:IPR035952|dip:DIP-60798N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:PkODM+LJUIm2icak0UjYA99sezc588 rogid:rMLMMVi9OcU6ksCBsNOREGL4uPA588 rigid:/+Vemi0U1dJHjv9zZkP55kBw0dA false 35s radiolabel:?-? - - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:P42287 uniprotkb:P46116 intact:EBI-122571|uniprotkb:Q9VLL2|ensemblmetazoa:FBpp0079313 intact:EBI-10098058 psi-mi:grk_drome(display_long)|uniprotkb:CG17610(orf name)|uniprotkb:grk(gene name)|psi-mi:grk(display_short) psi-mi:aara_prost(display_long)|uniprotkb:aarA(gene name)|psi-mi:aarA(display_short)|uniprotkb:Intramembrane serine protease(gene name synonym) psi-mi:"MI:0435"(protease assay) Stevenson et al. (2007) pubmed:17215357|doi:10.1073/pnas.0608140104|imex:IM-22498 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:588(prost)|taxid:588(Providencia stuartii) psi-mi:"MI:0570"(protein cleavage) psi-mi:"MI:0465"(DIP) intact:EBI-15618483|imex:IM-22498-2|dip:DIP-196277E - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-20922N|refseq:NP_476568.2|flybase:FBgn0001137|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007314"(oocyte anterior/posterior axis specification)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0008069"(dorsal/ventral axis specification, ovarian follicular epithelium)|go:"GO:0008070"(maternal determination of dorsal/ventral axis, ovarian follicular epithelium, germ-line encoded)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016325"(oocyte microtubule cytoskeleton organization)|go:"GO:0030381"(chorion-containing eggshell pattern formation)|go:"GO:0030714"(anterior/posterior axis specification, follicular epithelium)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0048263"(determination of dorsal identity)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR043403|rcsb pdb:5F5K|rcsb pdb:6PJP|rcsb pdb:6PJQ|rcsb pdb:6PJR|rcsb pdb:6PJU|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|ensemblmetazoa:FBgn0001137(gene)|ensemblmetazoa:FBtr0079708(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005615"(extracellular space) refseq:WP_004917931.1|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR022764|interpro:IPR035952|dip:DIP-60798N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:9TGh46UunwejPDdD4Zxav6Xbl2M7227 rogid:rMLMMVi9OcU6ksCBsNOREGL4uPA588 rigid:jFCmbGM/kYlGEiUF18nLm1+C3+I false 35s radiolabel:?-? - - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:P09391 uniprotkb:P42287 intact:EBI-9134140|uniprotkb:Q2M788|uniprotkb:Q6BF32|uniprotkb:P76691|ensemblbacteria:AAT48182|ensemblbacteria:BAE77868 intact:EBI-122571|uniprotkb:Q9VLL2|ensemblmetazoa:FBpp0079313 psi-mi:glpg_ecoli(display_long)|uniprotkb:Intramembrane serine protease(gene name synonym)|uniprotkb:JW5687(locus name)|uniprotkb:b3424(locus name)|uniprotkb:glpG(gene name)|psi-mi:glpG(display_short) psi-mi:grk_drome(display_long)|uniprotkb:CG17610(orf name)|uniprotkb:grk(gene name)|psi-mi:grk(display_short) psi-mi:"MI:0435"(protease assay) Stevenson et al. (2007) pubmed:17215357|doi:10.1073/pnas.0608140104|imex:IM-22498 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0570"(protein cleavage) psi-mi:"MI:0465"(DIP) intact:EBI-15618502|imex:IM-22498-3|dip:DIP-196278E - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_026220.1|refseq:WP_000928723.1|dip:DIP-9796N|ensemblbacteria:AAT48182(transcript)|ensemblbacteria:b3424(gene)|ensemblbacteria:BAE77868(gene)|ensemblbacteria:BAE77868(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0042802"(identical protein binding)|interpro:IPR022732|interpro:IPR022764|interpro:IPR023662|interpro:IPR035952|interpro:IPR038236|rcsb pdb:2IC8|rcsb pdb:2IRV|rcsb pdb:2LEP|rcsb pdb:2NRF|rcsb pdb:2O7L|rcsb pdb:2XOV|rcsb pdb:2XOW|rcsb pdb:2XTU|rcsb pdb:2XTV|rcsb pdb:3B44|rcsb pdb:3B45|rcsb pdb:3TXT|rcsb pdb:3UBB|rcsb pdb:3ZMH|rcsb pdb:3ZMI|rcsb pdb:3ZMJ|rcsb pdb:3ZOT|rcsb pdb:4H1D|rcsb pdb:4HDD|rcsb pdb:4NJN|rcsb pdb:4NJP|rcsb pdb:5F5B|rcsb pdb:5F5D|rcsb pdb:5F5G|rcsb pdb:5F5J|rcsb pdb:5F5K|rcsb pdb:5MT6|rcsb pdb:5MT7|rcsb pdb:5MT8|rcsb pdb:6PJ4|rcsb pdb:6PJ5|rcsb pdb:6PJ7|rcsb pdb:6PJ8|rcsb pdb:6PJ9|rcsb pdb:6PJA|rcsb pdb:6PJP|rcsb pdb:6PJQ|rcsb pdb:6PJR|rcsb pdb:6PJU|rcsb pdb:6VJ8|rcsb pdb:6VJ9|rcsb pdb:6XRO|rcsb pdb:6XRP|rcsb pdb:3ZEB dip:DIP-20922N|refseq:NP_476568.2|flybase:FBgn0001137|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007314"(oocyte anterior/posterior axis specification)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0008069"(dorsal/ventral axis specification, ovarian follicular epithelium)|go:"GO:0008070"(maternal determination of dorsal/ventral axis, ovarian follicular epithelium, germ-line encoded)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016325"(oocyte microtubule cytoskeleton organization)|go:"GO:0030381"(chorion-containing eggshell pattern formation)|go:"GO:0030714"(anterior/posterior axis specification, follicular epithelium)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0048263"(determination of dorsal identity)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR043403|rcsb pdb:5F5K|rcsb pdb:6PJP|rcsb pdb:6PJQ|rcsb pdb:6PJR|rcsb pdb:6PJU|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|ensemblmetazoa:FBgn0001137(gene)|ensemblmetazoa:FBtr0079708(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005615"(extracellular space) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:9oSV7b6N1B4CKLgucotWxJlZigU83333 rogid:9TGh46UunwejPDdD4Zxav6Xbl2M7227 rigid:J0pgGPSj88Z5QmBIfdhsHgcH3Jk false - 35s radiolabel:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)