#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P24158	uniprotkb:P24001-4	intact:EBI-465028|uniprotkb:Q9UQD8|ensembl:ENSP00000234347|ensembl:ENSP00000478977|uniprotkb:P15637|uniprotkb:P18078|uniprotkb:Q4VB09|uniprotkb:Q6LBM7|uniprotkb:Q4VB08|uniprotkb:Q6LBN2|uniprotkb:Q9UD25	intact:EBI-15570379|ensembl:ENSP00000380096|ensembl:ENSP00000447496|ensembl:ENSP00000447812	psi-mi:prtn3_human(display_long)|uniprotkb:MBN(gene name synonym)|uniprotkb:PRTN3(gene name)|psi-mi:PRTN3(display_short)|uniprotkb:Leukocyte proteinase 3(gene name synonym)|uniprotkb:AGP7(gene name synonym)|uniprotkb:Wegener autoantigen(gene name synonym)|uniprotkb:P29(gene name synonym)|uniprotkb:C-ANCA antigen(gene name synonym)|uniprotkb:Neutrophil proteinase 4(gene name synonym)	psi-mi:p24001-4(display_long)|uniprotkb:IL32(gene name)|psi-mi:IL32(display_short)|uniprotkb:NK4(gene name synonym)|uniprotkb:TAIF(gene name synonym)|uniprotkb:Natural killer cells protein 4(gene name synonym)|uniprotkb:Tumor necrosis factor alpha-inducing factor(gene name synonym)|uniprotkb:Alpha(isoform synonym)	psi-mi:"MI:0096"(pull down)	Novick et al. (2006)	pubmed:16488976|doi:10.1073/pnas.0511206103|imex:IM-23438	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15570389|imex:IM-23438-1|dip:DIP-197513E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000196415(gene)|ensembl:ENSG00000277804(gene)|ensembl:ENST00000234347(transcript)|ensembl:ENST00000612112(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006909"(phagocytosis)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0019899"(enzyme binding)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045217"(cell-cell junction maintenance)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072672"(neutrophil extravasation)|go:"GO:0097029"(mature conventional dendritic cell differentiation)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|mint:P24158|rcsb pdb:1FUJ|reactome:R-HSA-140875|reactome:R-HSA-449836|reactome:R-HSA-6798695|reactome:R-HSA-6803157|interpro:IPR001314(Peptidase S1A, chymotrypsin)|refseq:NP_002768.3|dip:DIP-31107N	intact:EBI-2866752(isoform-parent)|ensembl:ENSG00000008517(gene)|ensembl:ENST00000396887(transcript)|ensembl:ENST00000549213(transcript)|ensembl:ENST00000551122(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/04	2017/08/10	rogid:+28oFrY+yAY4MtIR0vfAfItyhrM9606	rogid:m3n21+eUpJdbedB0EfYTE1STXjk9606	rigid:8UA/jGb+QlnGGmBYfCK7AgIyBTI	false	-	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:P24158	uniprotkb:P24001-4	intact:EBI-465028|uniprotkb:Q9UQD8|ensembl:ENSP00000234347|ensembl:ENSP00000478977|uniprotkb:P15637|uniprotkb:P18078|uniprotkb:Q4VB09|uniprotkb:Q6LBM7|uniprotkb:Q4VB08|uniprotkb:Q6LBN2|uniprotkb:Q9UD25	intact:EBI-15570379|ensembl:ENSP00000380096|ensembl:ENSP00000447496|ensembl:ENSP00000447812	psi-mi:prtn3_human(display_long)|uniprotkb:MBN(gene name synonym)|uniprotkb:PRTN3(gene name)|psi-mi:PRTN3(display_short)|uniprotkb:Leukocyte proteinase 3(gene name synonym)|uniprotkb:AGP7(gene name synonym)|uniprotkb:Wegener autoantigen(gene name synonym)|uniprotkb:P29(gene name synonym)|uniprotkb:C-ANCA antigen(gene name synonym)|uniprotkb:Neutrophil proteinase 4(gene name synonym)	psi-mi:p24001-4(display_long)|uniprotkb:IL32(gene name)|psi-mi:IL32(display_short)|uniprotkb:NK4(gene name synonym)|uniprotkb:TAIF(gene name synonym)|uniprotkb:Natural killer cells protein 4(gene name synonym)|uniprotkb:Tumor necrosis factor alpha-inducing factor(gene name synonym)|uniprotkb:Alpha(isoform synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Novick et al. (2006)	pubmed:16488976|doi:10.1073/pnas.0511206103|imex:IM-23438	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15570406|imex:IM-23438-2|dip:DIP-197513E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000196415(gene)|ensembl:ENSG00000277804(gene)|ensembl:ENST00000234347(transcript)|ensembl:ENST00000612112(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006909"(phagocytosis)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0019899"(enzyme binding)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045217"(cell-cell junction maintenance)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072672"(neutrophil extravasation)|go:"GO:0097029"(mature conventional dendritic cell differentiation)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|mint:P24158|rcsb pdb:1FUJ|reactome:R-HSA-140875|reactome:R-HSA-449836|reactome:R-HSA-6798695|reactome:R-HSA-6803157|interpro:IPR001314(Peptidase S1A, chymotrypsin)|refseq:NP_002768.3|dip:DIP-31107N	intact:EBI-2866752(isoform-parent)|ensembl:ENSG00000008517(gene)|ensembl:ENST00000396887(transcript)|ensembl:ENST00000549213(transcript)|ensembl:ENST00000551122(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/04	2017/08/10	rogid:+28oFrY+yAY4MtIR0vfAfItyhrM9606	rogid:m3n21+eUpJdbedB0EfYTE1STXjk9606	rigid:8UA/jGb+QlnGGmBYfCK7AgIyBTI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P24158	uniprotkb:P24001-4	intact:EBI-465028|uniprotkb:Q9UQD8|ensembl:ENSP00000234347|ensembl:ENSP00000478977|uniprotkb:P15637|uniprotkb:P18078|uniprotkb:Q4VB09|uniprotkb:Q6LBM7|uniprotkb:Q4VB08|uniprotkb:Q6LBN2|uniprotkb:Q9UD25	intact:EBI-15570379|ensembl:ENSP00000380096|ensembl:ENSP00000447496|ensembl:ENSP00000447812	psi-mi:prtn3_human(display_long)|uniprotkb:MBN(gene name synonym)|uniprotkb:PRTN3(gene name)|psi-mi:PRTN3(display_short)|uniprotkb:Leukocyte proteinase 3(gene name synonym)|uniprotkb:AGP7(gene name synonym)|uniprotkb:Wegener autoantigen(gene name synonym)|uniprotkb:P29(gene name synonym)|uniprotkb:C-ANCA antigen(gene name synonym)|uniprotkb:Neutrophil proteinase 4(gene name synonym)	psi-mi:p24001-4(display_long)|uniprotkb:IL32(gene name)|psi-mi:IL32(display_short)|uniprotkb:NK4(gene name synonym)|uniprotkb:TAIF(gene name synonym)|uniprotkb:Natural killer cells protein 4(gene name synonym)|uniprotkb:Tumor necrosis factor alpha-inducing factor(gene name synonym)|uniprotkb:Alpha(isoform synonym)	psi-mi:"MI:0435"(protease assay)	Novick et al. (2006)	pubmed:16488976|doi:10.1073/pnas.0511206103|imex:IM-23438	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0570"(protein cleavage)	psi-mi:"MI:0465"(DIP)	intact:EBI-15570423|imex:IM-23438-3|dip:DIP-197513E	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000196415(gene)|ensembl:ENSG00000277804(gene)|ensembl:ENST00000234347(transcript)|ensembl:ENST00000612112(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006909"(phagocytosis)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0019899"(enzyme binding)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045217"(cell-cell junction maintenance)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072672"(neutrophil extravasation)|go:"GO:0097029"(mature conventional dendritic cell differentiation)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|mint:P24158|rcsb pdb:1FUJ|reactome:R-HSA-140875|reactome:R-HSA-449836|reactome:R-HSA-6798695|reactome:R-HSA-6803157|interpro:IPR001314(Peptidase S1A, chymotrypsin)|refseq:NP_002768.3|dip:DIP-31107N	intact:EBI-2866752(isoform-parent)|ensembl:ENSG00000008517(gene)|ensembl:ENST00000396887(transcript)|ensembl:ENST00000549213(transcript)|ensembl:ENST00000551122(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/04	2017/08/10	rogid:+28oFrY+yAY4MtIR0vfAfItyhrM9606	rogid:m3n21+eUpJdbedB0EfYTE1STXjk9606	rigid:8UA/jGb+QlnGGmBYfCK7AgIyBTI	false	-	125i radiolabel:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)