#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9U2M5	uniprotkb:Q9XTR1	intact:EBI-2420074|uniprotkb:O77085|ensemblmetazoa:Y38F1A.5.1|ensemblmetazoa:Y38F1A.5.2	intact:EBI-14063019|ensemblmetazoa:F18H3.5b.1|uniprotkb:G5EFI3	psi-mi:ccnd_caeel(display_long)|uniprotkb:cyd-1(gene name)|psi-mi:cyd-1(display_short)|uniprotkb:Y38F1A.5(orf name)	psi-mi:cdk4_caeel(display_long)|uniprotkb:Cell division protein kinase 4(gene name synonym)|uniprotkb:F18H3.5(orf name)|uniprotkb:cdk-4(gene name)|psi-mi:cdk-4(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Park et al. (1999)	pubmed:10518501|imex:IM-25743	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14063636|imex:IM-25743-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_496763.1|wormbase:Y38F1A.5|interpro:IPR013763(Cyclin-related)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR036915|reactome:R-CEL-1538133|reactome:R-CEL-2559586|reactome:R-CEL-5689880|reactome:R-CEL-6804116|reactome:R-CEL-68911|reactome:R-CEL-68949|reactome:R-CEL-69017|reactome:R-CEL-69273|reactome:R-CEL-69563|reactome:R-CEL-69656|interpro:IPR039361|reactome:R-CEL-187577|ensemblmetazoa:WBGene00000870(gene)|ensemblmetazoa:Y38F1A.5.1(transcript)|ensemblmetazoa:Y38F1A.5.2(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007506"(gonadal mesoderm development)|go:"GO:0007530"(sex determination)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0008406"(gonad development)|go:"GO:0008584"(male gonad development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0032875"(regulation of DNA endoreduplication)|go:"GO:0032877"(positive regulation of DNA endoreduplication)|go:"GO:0040035"(hermaphrodite genitalia development)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0044843"(cell cycle G1/S phase transition)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0090727"(positive regulation of brood size)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904787"(positive regulation of asymmetric protein localization involved in cell fate determination)	reactome:R-CEL-8934593|ensemblmetazoa:F18H3.5b.1(transcript)|ensemblmetazoa:WBGene00000406(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007530"(sex determination)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0008584"(male gonad development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0016592"(mediator complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0032877"(positive regulation of DNA endoreduplication)|go:"GO:0040035"(hermaphrodite genitalia development)|go:"GO:0044843"(cell cycle G1/S phase transition)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090727"(positive regulation of brood size)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|refseq:NP_001024591.1|refseq:NP_510256.1|wormbase:F18H3.5a|wormbase:F18H3.5b|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)	-	-	-	figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells)	-	2017/05/19	2017/06/02	rogid:iekekZUkN2sk+xJJxtyQQhHL6M46239	rogid:kIXmmfDDEWhNhw3ryo5I/dpFINI6239	rigid:xrDyTmABUca9WwEU1D4KRWefnBE	false	ha tag:c-c	flag tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9U2M5	uniprotkb:Q9XTR1	intact:EBI-2420074|uniprotkb:O77085|ensemblmetazoa:Y38F1A.5.1|ensemblmetazoa:Y38F1A.5.2	intact:EBI-14063019|ensemblmetazoa:F18H3.5b.1|uniprotkb:G5EFI3	psi-mi:ccnd_caeel(display_long)|uniprotkb:cyd-1(gene name)|psi-mi:cyd-1(display_short)|uniprotkb:Y38F1A.5(orf name)	psi-mi:cdk4_caeel(display_long)|uniprotkb:Cell division protein kinase 4(gene name synonym)|uniprotkb:F18H3.5(orf name)|uniprotkb:cdk-4(gene name)|psi-mi:cdk-4(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Park et al. (1999)	pubmed:10518501|imex:IM-25743	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14063644|imex:IM-25743-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_496763.1|wormbase:Y38F1A.5|interpro:IPR013763(Cyclin-related)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR036915|reactome:R-CEL-1538133|reactome:R-CEL-2559586|reactome:R-CEL-5689880|reactome:R-CEL-6804116|reactome:R-CEL-68911|reactome:R-CEL-68949|reactome:R-CEL-69017|reactome:R-CEL-69273|reactome:R-CEL-69563|reactome:R-CEL-69656|interpro:IPR039361|reactome:R-CEL-187577|ensemblmetazoa:WBGene00000870(gene)|ensemblmetazoa:Y38F1A.5.1(transcript)|ensemblmetazoa:Y38F1A.5.2(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007506"(gonadal mesoderm development)|go:"GO:0007530"(sex determination)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0008406"(gonad development)|go:"GO:0008584"(male gonad development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0032875"(regulation of DNA endoreduplication)|go:"GO:0032877"(positive regulation of DNA endoreduplication)|go:"GO:0040035"(hermaphrodite genitalia development)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0044843"(cell cycle G1/S phase transition)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0090727"(positive regulation of brood size)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904787"(positive regulation of asymmetric protein localization involved in cell fate determination)	reactome:R-CEL-8934593|ensemblmetazoa:F18H3.5b.1(transcript)|ensemblmetazoa:WBGene00000406(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007530"(sex determination)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0008584"(male gonad development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0016592"(mediator complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0032877"(positive regulation of DNA endoreduplication)|go:"GO:0040035"(hermaphrodite genitalia development)|go:"GO:0044843"(cell cycle G1/S phase transition)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090727"(positive regulation of brood size)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|refseq:NP_001024591.1|refseq:NP_510256.1|wormbase:F18H3.5a|wormbase:F18H3.5b|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)	-	-	-	figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells)	-	2017/05/19	2017/06/02	rogid:iekekZUkN2sk+xJJxtyQQhHL6M46239	rogid:kIXmmfDDEWhNhw3ryo5I/dpFINI6239	rigid:xrDyTmABUca9WwEU1D4KRWefnBE	false	ha tag:c-c	flag tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)