#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P43601	uniprotkb:P53855	intact:EBI-22968|uniprotkb:D6VTQ1|ensemblfungi:YFR021W	intact:EBI-29212|uniprotkb:D6W0V1|ensemblfungi:YNL242W	psi-mi:atg18_yeast(display_long)|uniprotkb:NMR1(gene name synonym)|uniprotkb:YFR021W(locus name)|uniprotkb:ATG18(gene name)|psi-mi:ATG18(display_short)|uniprotkb:AUT10(gene name synonym)|uniprotkb:CVT18(gene name synonym)|uniprotkb:SVP1(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 18(gene name synonym)|uniprotkb:Swollen vacuole phenotype protein 1(gene name synonym)|uniprotkb:Needed for premeiotic replication protein 1(gene name synonym)	psi-mi:atg2_yeast(display_long)|uniprotkb:Sporulation-specific protein 72(gene name synonym)|uniprotkb:YNL242W(locus name)|uniprotkb:N1106(orf name)|uniprotkb:ATG2(gene name)|psi-mi:ATG2(display_short)|uniprotkb:APG2(gene name synonym)|uniprotkb:AUT8(gene name synonym)|uniprotkb:SPO72(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Rieter et al. (2013)	imex:IM-25116|pubmed:23230146	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11685224|imex:IM-25116-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_444297.1|sgd:S000001917|dip:DIP-5185N|mint:P43601|ensemblfungi:YFR021W(gene)|ensemblfungi:YFR021W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006497"(protein lipidation)|go:"GO:0006624"(vacuolar protein processing)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061908"(phagophore)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070772"(PAS complex)|go:"GO:0071944"(cell periphery)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:6KYB|reactome:R-SCE-1632852	refseq:NP_014157.1|sgd:S000005186|dip:DIP-2620N|mint:P53855|ensemblfungi:YNL242W(gene)|ensemblfungi:YNL242W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|go:"GO:0061908"(phagophore)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026885|interpro:IPR026886	-	crc64:06B2DFAF842AE933	crc64:54FDDF56297FFF99	figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2016/04/07	2016/04/07	rogid:dUJPRtNzoRFY/sp9LSteu2xC13A559292	rogid:RAgkv6PtLHv/KywG517+jp11EFE559292	rigid:nRNlkAChVJmvdoGkFNB5nsqmPrw	false	necessary binding region:42-47,90-94|mutation disrupting interaction strength:47-47,90-94,42-44	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43601	uniprotkb:P53855	intact:EBI-22968|uniprotkb:D6VTQ1|ensemblfungi:YFR021W	intact:EBI-29212|uniprotkb:D6W0V1|ensemblfungi:YNL242W	psi-mi:atg18_yeast(display_long)|uniprotkb:NMR1(gene name synonym)|uniprotkb:YFR021W(locus name)|uniprotkb:ATG18(gene name)|psi-mi:ATG18(display_short)|uniprotkb:AUT10(gene name synonym)|uniprotkb:CVT18(gene name synonym)|uniprotkb:SVP1(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 18(gene name synonym)|uniprotkb:Swollen vacuole phenotype protein 1(gene name synonym)|uniprotkb:Needed for premeiotic replication protein 1(gene name synonym)	psi-mi:atg2_yeast(display_long)|uniprotkb:Sporulation-specific protein 72(gene name synonym)|uniprotkb:YNL242W(locus name)|uniprotkb:N1106(orf name)|uniprotkb:ATG2(gene name)|psi-mi:ATG2(display_short)|uniprotkb:APG2(gene name synonym)|uniprotkb:AUT8(gene name synonym)|uniprotkb:SPO72(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Rieter et al. (2013)	imex:IM-25116|pubmed:23230146	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11685324|imex:IM-25116-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_444297.1|sgd:S000001917|dip:DIP-5185N|mint:P43601|ensemblfungi:YFR021W(gene)|ensemblfungi:YFR021W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006497"(protein lipidation)|go:"GO:0006624"(vacuolar protein processing)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061908"(phagophore)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070772"(PAS complex)|go:"GO:0071944"(cell periphery)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:6KYB|reactome:R-SCE-1632852	refseq:NP_014157.1|sgd:S000005186|dip:DIP-2620N|mint:P53855|ensemblfungi:YNL242W(gene)|ensemblfungi:YNL242W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|go:"GO:0061908"(phagophore)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026885|interpro:IPR026886	-	crc64:06B2DFAF842AE933	crc64:54FDDF56297FFF99	figure legend:Fig. 2A, 7E|comment:Interaction was not observed in ATG14-/- cells, which the authors interpreted as indicating that the interaction requires  the  generation  of PtDIns3P.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/04/07	2016/04/07	rogid:dUJPRtNzoRFY/sp9LSteu2xC13A559292	rogid:RAgkv6PtLHv/KywG517+jp11EFE559292	rigid:nRNlkAChVJmvdoGkFNB5nsqmPrw	false	myc tag:c-c|mutation decreasing interaction strength:90-94|necessary binding region:42-47,90-94|mutation disrupting interaction strength:47-47,90-94,42-44	protein a tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
chebi:"CHEBI:16851"	uniprotkb:P43601	intact:EBI-1257121	intact:EBI-22968|uniprotkb:D6VTQ1|ensemblfungi:YFR021W	psi-mi:1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate(display_short)|psi-mi:"CHEBI:16851"(display_long)	psi-mi:atg18_yeast(display_long)|uniprotkb:NMR1(gene name synonym)|uniprotkb:YFR021W(locus name)|uniprotkb:ATG18(gene name)|psi-mi:ATG18(display_short)|uniprotkb:AUT10(gene name synonym)|uniprotkb:CVT18(gene name synonym)|uniprotkb:SVP1(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 18(gene name synonym)|uniprotkb:Swollen vacuole phenotype protein 1(gene name synonym)|uniprotkb:Needed for premeiotic replication protein 1(gene name synonym)	psi-mi:"MI:0049"(filter binding)	Rieter et al. (2013)	imex:IM-25116|pubmed:23230146	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11685350|imex:IM-25116-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_444297.1|sgd:S000001917|dip:DIP-5185N|mint:P43601|ensemblfungi:YFR021W(gene)|ensemblfungi:YFR021W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006497"(protein lipidation)|go:"GO:0006624"(vacuolar protein processing)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061908"(phagophore)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070772"(PAS complex)|go:"GO:0071944"(cell periphery)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:6KYB|reactome:R-SCE-1632852	-	-	crc64:06B2DFAF842AE933	figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/04/07	2016/05/26	-	rogid:dUJPRtNzoRFY/sp9LSteu2xC13A559292	-	false	-	myc tag:c-c|mutation disrupting interaction strength:285-286	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P43601	uniprotkb:P53855	intact:EBI-22968|uniprotkb:D6VTQ1|ensemblfungi:YFR021W	intact:EBI-29212|uniprotkb:D6W0V1|ensemblfungi:YNL242W	psi-mi:atg18_yeast(display_long)|uniprotkb:NMR1(gene name synonym)|uniprotkb:YFR021W(locus name)|uniprotkb:ATG18(gene name)|psi-mi:ATG18(display_short)|uniprotkb:AUT10(gene name synonym)|uniprotkb:CVT18(gene name synonym)|uniprotkb:SVP1(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 18(gene name synonym)|uniprotkb:Swollen vacuole phenotype protein 1(gene name synonym)|uniprotkb:Needed for premeiotic replication protein 1(gene name synonym)	psi-mi:atg2_yeast(display_long)|uniprotkb:Sporulation-specific protein 72(gene name synonym)|uniprotkb:YNL242W(locus name)|uniprotkb:N1106(orf name)|uniprotkb:ATG2(gene name)|psi-mi:ATG2(display_short)|uniprotkb:APG2(gene name synonym)|uniprotkb:AUT8(gene name synonym)|uniprotkb:SPO72(gene name synonym)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Rieter et al. (2013)	imex:IM-25116|pubmed:23230146	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11685807|imex:IM-25116-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_444297.1|sgd:S000001917|dip:DIP-5185N|mint:P43601|ensemblfungi:YFR021W(gene)|ensemblfungi:YFR021W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006497"(protein lipidation)|go:"GO:0006624"(vacuolar protein processing)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061908"(phagophore)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070772"(PAS complex)|go:"GO:0071944"(cell periphery)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:6KYB|reactome:R-SCE-1632852	refseq:NP_014157.1|sgd:S000005186|dip:DIP-2620N|mint:P53855|ensemblfungi:YNL242W(gene)|ensemblfungi:YNL242W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|go:"GO:0061908"(phagophore)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026885|interpro:IPR026886	-	crc64:06B2DFAF842AE933	crc64:54FDDF56297FFF99	figure legend:Fig. 7A-D|comment:Interaction increased in atg3-/- cells, and was complete lost in atg13-/- cells.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2016/04/07	2016/04/08	rogid:dUJPRtNzoRFY/sp9LSteu2xC13A559292	rogid:RAgkv6PtLHv/KywG517+jp11EFE559292	rigid:nRNlkAChVJmvdoGkFNB5nsqmPrw	false	venus c-terminal fragment:c-c|mutation decreasing interaction strength:90-94|mutation disrupting interaction strength:285-286	venus n-terminal fragment:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)