#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q6ZVN8	uniprotkb:Q8IU80	intact:EBI-10900704|uniprotkb:B1ALI7|uniprotkb:Q2PQ63|uniprotkb:Q6IMF6|uniprotkb:Q8NAH2|uniprotkb:Q8WVJ5|ensembl:ENSP00000337014	intact:EBI-11686504|uniprotkb:B0QYB4|uniprotkb:B0QYB7|uniprotkb:B0QYB8|uniprotkb:Q5TI06|uniprotkb:Q6ICC2|uniprotkb:Q6UXD8|uniprotkb:Q8IUE2|uniprotkb:Q8IXV8	psi-mi:rgmc_human(display_long)|uniprotkb:HJV(gene name)|psi-mi:HJV(display_short)|uniprotkb:HFE2(gene name synonym)|uniprotkb:Hemochromatosis type 2 protein(gene name synonym)|uniprotkb:Hemojuvelin BMP coreceptor(gene name synonym)|uniprotkb:RGM domain family member C(gene name synonym)|uniprotkb:RGMC(gene name synonym)	psi-mi:tmps6_human(display_long)|uniprotkb:Matriptase-2(gene name synonym)|uniprotkb:UNQ354/PRO618(orf name)|uniprotkb:TMPRSS6(gene name)|psi-mi:TMPRSS6(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Altamura et al. (2010)	imex:IM-25100|pubmed:20704562	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11686846|imex:IM-25100-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001303696.1|refseq:NP_660320.3|refseq:NP_973733.1|refseq:NP_998817.1|refseq:NP_998818.1|refseq:XP_005272989.1|ensembl:ENSG00000168509(gene)|ensembl:ENST00000336751(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0032924"(activin receptor signaling pathway)|go:"GO:0036122"(BMP binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0070724"(BMP receptor complex)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0098797"(plasma membrane protein complex)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990712"(HFE-transferrin receptor complex)|interpro:IPR009496(Repulsive guidance molecule, C-terminal)|interpro:IPR010536(Repulsive guidance molecule, N-terminal)|interpro:IPR033606|interpro:IPR040287|rcsb pdb:4UI1|rcsb pdb:6Z3L|reactome:R-HSA-373752|dip:DIP-61608N	refseq:NP_001275929.1|refseq:NP_001275930.1|refseq:NP_705837.1|interpro:IPR000859(CUB)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR017118(Matriptase-2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR000082(SEA)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR018114|interpro:IPR033116|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0033619"(membrane protein proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0097264"(self proteolysis)|reactome:R-HSA-1442490|reactome:R-HSA-1474228|interpro:IPR035914|interpro:IPR036055|interpro:IPR036364|interpro:IPR043504	-	-	-	figure legend:6A|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2016/03/08	2016/04/12	rogid:/AJNZs236A0oBXK8DPnb6jpixgs9606	rogid:XVG3Nxb6mD2FtxZ+9YugTbLUNCo9606	rigid:NMD5VTYxCr2gzWYZHp6xC2T7iiA	false	myc tag:n-n	mutation with no effect:141-141|flag tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)