#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9UBZ9	uniprotkb:Q6NZ36	intact:EBI-7353917|intact:MINT-140323|uniprotkb:Q53SI7|uniprotkb:O95941|uniprotkb:Q9NUP2|uniprotkb:Q9C0J4|ensembl:ENSP00000258428	intact:EBI-2817693|uniprotkb:A8MQT6|uniprotkb:Q6ZT64|uniprotkb:A6PW40|uniprotkb:Q71M24|uniprotkb:A6PW39|uniprotkb:A6PW41|uniprotkb:Q96ND7|uniprotkb:F2Z2L4|intact:EBI-28984154|ensembl:ENSP00000367808	psi-mi:rev1_human(display_long)|uniprotkb:REV1(gene name)|psi-mi:REV1(display_short)|uniprotkb:REV1L(gene name synonym)|uniprotkb:Rev1-like terminal deoxycytidyl transferase(gene name synonym)|uniprotkb:Alpha integrin-binding protein 80(gene name synonym)	psi-mi:fap20_human(display_long)|uniprotkb:FANCA-associated protein of 20 kDa(gene name synonym)|uniprotkb:Fanconi anemia-associated protein of 20 kDa(gene name synonym)|uniprotkb:FP7162(orf name)|uniprotkb:FAAP20(gene name)|psi-mi:FAAP20(display_short)|uniprotkb:C1orf86(gene name synonym)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Lim et al. (2015)	pubmed:26318859|imex:IM-24702	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-11360756|imex:IM-24702-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001308383.1|refseq:NP_001308384.1|refseq:NP_001308387.1|refseq:NP_001308388.1|refseq:NP_001308389.1|refseq:NP_001032961.1|refseq:NP_057400.1|ensembl:ENSG00000135945(gene)|ensembl:ENST00000258428(transcript)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0009411"(response to UV)|go:"GO:0017125"(deoxycytidyl transferase activity)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0070987"(error-free translesion synthesis)|interpro:IPR001126(UMUC-like DNA-repair protein)|interpro:IPR001357(BRCT)|interpro:IPR012112(DNA repair protein, Rev1)|interpro:IPR017961|interpro:IPR025527|interpro:IPR031991|interpro:IPR036420|interpro:IPR036775|interpro:IPR038401|interpro:IPR043128|interpro:IPR043502|rcsb pdb:2EBW|rcsb pdb:2LSI|rcsb pdb:2LSK|rcsb pdb:2LSY|rcsb pdb:2N1G|rcsb pdb:3GQC|rcsb pdb:3VU7|rcsb pdb:4BA9|rcsb pdb:4EXT|rcsb pdb:4GK0|rcsb pdb:4GK5|rcsb pdb:5VZM|rcsb pdb:6ASR|rcsb pdb:6AXD|rcsb pdb:6WS0|rcsb pdb:6WS5|reactome:R-HSA-110312|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169	refseq:NP_001269599.1|refseq:NP_001269600.1|refseq:NP_001269601.1|refseq:NP_001269602.1|refseq:NP_872339.2|ensembl:ENST00000378543|ensembl:ENSP00000367804|ensembl:ENSP00000367808|ensembl:ENST00000400918|ensembl:ENSP00000383709|ensembl:ENST00000414253|ensembl:ENSP00000410450|refseq:NP_001243874.1|refseq:NP_001243875.1|refseq:NP_001243876.1|ensembl:ENSG00000162585(gene)|ensembl:ENST00000378546(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030054"(cell junction)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0140036"(ubiquitin-dependent protein binding)|interpro:IPR031490|interpro:IPR031491|rcsb pdb:2MUQ|rcsb pdb:2MUR|rcsb pdb:3WWQ|reactome:R-HSA-6783310|dip:DIP-59917N	-	comment:mint|comment:homomint|function:Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents	-	figure legend:f3 sf3 sf4 sf5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:395.86x10^-6(molar)	2015/11/04	2015/11/04	rogid:nqlZzaFe/OYk+xqMSxqvMxPULXI9606	rogid:Jn2G9RrMwRMLLW4BQ3mBxTXoLkA9606	rigid:y0Vz5+IjLYj3VUehjKrA6dEGj7Q	false	binding-associated region:44-132|mutation disrupting interaction:104-104,106-106	binding-associated region:133-180	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UBZ9	uniprotkb:Q6NZ36	intact:EBI-7353917|intact:MINT-140323|uniprotkb:Q53SI7|uniprotkb:O95941|uniprotkb:Q9NUP2|uniprotkb:Q9C0J4|ensembl:ENSP00000258428	intact:EBI-2817693|uniprotkb:A8MQT6|uniprotkb:Q6ZT64|uniprotkb:A6PW40|uniprotkb:Q71M24|uniprotkb:A6PW39|uniprotkb:A6PW41|uniprotkb:Q96ND7|uniprotkb:F2Z2L4|intact:EBI-28984154|ensembl:ENSP00000367808	psi-mi:rev1_human(display_long)|uniprotkb:REV1(gene name)|psi-mi:REV1(display_short)|uniprotkb:REV1L(gene name synonym)|uniprotkb:Rev1-like terminal deoxycytidyl transferase(gene name synonym)|uniprotkb:Alpha integrin-binding protein 80(gene name synonym)	psi-mi:fap20_human(display_long)|uniprotkb:FANCA-associated protein of 20 kDa(gene name synonym)|uniprotkb:Fanconi anemia-associated protein of 20 kDa(gene name synonym)|uniprotkb:FP7162(orf name)|uniprotkb:FAAP20(gene name)|psi-mi:FAAP20(display_short)|uniprotkb:C1orf86(gene name synonym)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Lim et al. (2015)	pubmed:26318859|imex:IM-24702	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-11360799|imex:IM-24702-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001308383.1|refseq:NP_001308384.1|refseq:NP_001308387.1|refseq:NP_001308388.1|refseq:NP_001308389.1|refseq:NP_001032961.1|refseq:NP_057400.1|ensembl:ENSG00000135945(gene)|ensembl:ENST00000258428(transcript)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0009411"(response to UV)|go:"GO:0017125"(deoxycytidyl transferase activity)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0070987"(error-free translesion synthesis)|interpro:IPR001126(UMUC-like DNA-repair protein)|interpro:IPR001357(BRCT)|interpro:IPR012112(DNA repair protein, Rev1)|interpro:IPR017961|interpro:IPR025527|interpro:IPR031991|interpro:IPR036420|interpro:IPR036775|interpro:IPR038401|interpro:IPR043128|interpro:IPR043502|rcsb pdb:2EBW|rcsb pdb:2LSI|rcsb pdb:2LSK|rcsb pdb:2LSY|rcsb pdb:2N1G|rcsb pdb:3GQC|rcsb pdb:3VU7|rcsb pdb:4BA9|rcsb pdb:4EXT|rcsb pdb:4GK0|rcsb pdb:4GK5|rcsb pdb:5VZM|rcsb pdb:6ASR|rcsb pdb:6AXD|rcsb pdb:6WS0|rcsb pdb:6WS5|reactome:R-HSA-110312|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169	refseq:NP_001269599.1|refseq:NP_001269600.1|refseq:NP_001269601.1|refseq:NP_001269602.1|refseq:NP_872339.2|ensembl:ENST00000378543|ensembl:ENSP00000367804|ensembl:ENSP00000367808|ensembl:ENST00000400918|ensembl:ENSP00000383709|ensembl:ENST00000414253|ensembl:ENSP00000410450|refseq:NP_001243874.1|refseq:NP_001243875.1|refseq:NP_001243876.1|ensembl:ENSG00000162585(gene)|ensembl:ENST00000378546(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030054"(cell junction)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0140036"(ubiquitin-dependent protein binding)|interpro:IPR031490|interpro:IPR031491|rcsb pdb:2MUQ|rcsb pdb:2MUR|rcsb pdb:3WWQ|reactome:R-HSA-6783310|dip:DIP-59917N	-	comment:mint|comment:homomint|function:Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents	-	figure legend:f4 f5 sf5 sf9|comment:"We decided to examine the effect of the interaction  between UBZ4 and ubiquitin on the BRCT binding to UBZ4. We performed  an NMR titration experiment, questioning whether ubiquitin  and BRCT compete for the interaction with UBZ4 or if the  binding surface of BRCT is separate from the ubiquitin binding site  on UBZ4. Unlabeled BRCT was titrated into a 1:2 mixture of  15N-UBZ4 and unlabeled ubiquitin. As shown in Fig. 4A and B, addition  of BRCT resulted in peak broadening and CSP in some amide  resonances, indicating that BRCT can bind to the UBZ4–ubiquitin  complex and that the binding is in the intermediate to fast  exchange on the NMR time scale. Moreover, this result did not  show the peaks returning to the position of 15N-UBZ4 bound to  BRCT, implying that BRCT does not compete with ubiquitin or displace  it from a single binding site"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:39586.0x10^-6(molar)	2015/11/04	2015/11/04	rogid:nqlZzaFe/OYk+xqMSxqvMxPULXI9606	rogid:Jn2G9RrMwRMLLW4BQ3mBxTXoLkA9606	rigid:y0Vz5+IjLYj3VUehjKrA6dEGj7Q	false	binding-associated region:44-132	binding-associated region:133-180	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)