#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O60337 uniprotkb:Q14534 intact:EBI-2684600|uniprotkb:A5PKZ4|uniprotkb:O14670|uniprotkb:Q86X77|uniprotkb:D3DTC8|intact:EBI-28971061|ensembl:ENSP00000274140|uniprotkb:B4DKJ2|uniprotkb:B4DT33 intact:EBI-3905171|uniprotkb:Q9UEK6|ensembl:ENSP00000265896|uniprotkb:Q9UNR6 psi-mi:marh6_human(display_long)|uniprotkb:MARCHF6(gene name)|psi-mi:MARCHF6(display_short)|uniprotkb:Doa10 homolog(gene name synonym)|uniprotkb:KIAA0597(gene name synonym)|uniprotkb:MARCH6(gene name synonym)|uniprotkb:Membrane-associated RING finger protein 6(gene name synonym)|uniprotkb:Membrane-associated RING-CH protein VI(gene name synonym)|uniprotkb:Protein TEB-4(gene name synonym)|uniprotkb:RING finger protein 176(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MARCHF6(gene name synonym)|uniprotkb:RNF176(gene name synonym)|uniprotkb:TEB4(gene name synonym) psi-mi:erg1_human(display_long)|uniprotkb:SQLE(gene name)|psi-mi:SQLE(display_short)|uniprotkb:ERG1(gene name synonym)|uniprotkb:Squalene epoxidase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zelcer et al. (2014) imex:IM-24145|pubmed:24449766 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-10815110|imex:IM-24145-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000274140|ensembl:ENST00000449913|ensembl:ENSP00000414643|ensembl:ENST00000503788|ensembl:ENSP00000425930|refseq:NP_005876.2|ensembl:ENSG00000145495(gene)|ensembl:ENST00000274140(transcript)|go:"GO:0000835"(ER ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|refseq:NP_001257589.1|refseq:NP_001257590.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:O60337|reactome:R-HSA-901032|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|dip:DIP-56134N refseq:NP_003120.2|ensembl:ENSG00000104549(gene)|go:"GO:0004506"(squalene monooxygenase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006725"(cellular aromatic compound metabolic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071949"(FAD binding)|go:"GO:0140042"(lipid droplet formation)|interpro:IPR013698(Squalene epoxidase)|interpro:IPR036188|interpro:IPR040125|mint:Q14534|rcsb pdb:6C6N|rcsb pdb:6C6P|rcsb pdb:6C6R|reactome:R-HSA-191273|reactome:R-HSA-2426168|ensembl:ENST00000265896(transcript) - - - figure legend:f3c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/05/04 2015/05/04 rogid:ow2W2xIcL82tgIHRS0SxlY4Ffjs9606 rogid:jZnV6eRSD75A7YVspfL6SBq8XkA9606 rigid:arch1fgXxSdmZOya+n0oafeJPsw false myc tag:?-?|mutation increasing interaction:9-9 v5 tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)