#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O95793-2 uniprotkb:P04591-PRO_0000038594 intact:EBI-358189|ensembl:ENSP00000323443|ensembl:ENSP00000345425|ensembl:ENSP00000353604 intact:EBI-9871255 psi-mi:o95793-2(display_long)|uniprotkb:STAU1(gene name)|psi-mi:STAU1(display_short)|uniprotkb:STAU(gene name synonym) psi-mi:p04591-pro_0000038594(display_long)|uniprotkb:gag(gene name)|psi-mi:gag(display_short)|uniprotkb:Pr55Gag(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ghoujal et al. (2012) pubmed:22978549|imex:IM-24875 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:11706(hv1h2)|taxid:11706("Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1)") psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-10689962|imex:IM-24875-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-358174(stau_human)|ensembl:ENSG00000124214(gene)|ensembl:ENST00000340954(transcript)|ensembl:ENST00000347458(transcript)|ensembl:ENST00000360426(transcript)|uniprotkb:O95793-2(isoform-parent) intact:EBI-6163428(chain-parent) - - chain-seq-start:133|chain-seq-end:363 figure legend:1B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2015/03/06 2015/12/17 rogid:+JW/UIpMSSJSWv/4RT/yCLYjaUo9606 rogid:NJ62KblcsbHWlDc+IpZFGufRPjU11706 rigid:enL9+GWStchbi+hgWnmZU5ix2mY false ha tag:c-c|fusion protein:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O95793-2 uniprotkb:Q96H20 intact:EBI-358189|ensembl:ENSP00000323443|ensembl:ENSP00000345425|ensembl:ENSP00000353604 intact:EBI-747719|uniprotkb:Q8IXY3|uniprotkb:Q9UN50|ensembl:ENSP00000421380 psi-mi:o95793-2(display_long)|uniprotkb:STAU1(gene name)|psi-mi:STAU1(display_short)|uniprotkb:STAU(gene name synonym) psi-mi:snf8_human(display_long)|uniprotkb:ELL-associated protein of 30 kDa(gene name synonym)|uniprotkb:SNF8(gene name)|psi-mi:SNF8(display_short)|uniprotkb:EAP30(gene name synonym)|uniprotkb:ESCRT-II complex subunit VPS22(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ghoujal et al. (2012) pubmed:22978549|imex:IM-24875 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-10689962|imex:IM-24875-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-358174(stau_human)|ensembl:ENSG00000124214(gene)|ensembl:ENST00000340954(transcript)|ensembl:ENST00000347458(transcript)|ensembl:ENST00000360426(transcript)|uniprotkb:O95793-2(isoform-parent) refseq:NP_009172.2|refseq:NP_001304121.1|refseq:NP_001304122.1|refseq:NP_001304123.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016247"(channel regulator activity)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903772"(regulation of viral budding via host ESCRT complex)|interpro:IPR016689(ESCRT-2 complex, Snf8)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040608|mint:Q96H20|rcsb pdb:2ZME|rcsb pdb:3CUQ|reactome:R-HSA-917729|reactome:R-HSA-9610379|ensembl:ENSG00000159210(gene)|ensembl:ENST00000502492(transcript)|go:"GO:0000814"(ESCRT II complex) - - - figure legend:1B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2015/03/06 2015/12/17 rogid:+JW/UIpMSSJSWv/4RT/yCLYjaUo9606 rogid:FyjlBpOt9okBFV8Z+g8YLUeyCm49606 rigid:enL9+GWStchbi+hgWnmZU5ix2mY false ha tag:c-c|fusion protein:n-n flag tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P04591-PRO_0000038594 uniprotkb:O95793-2 intact:EBI-9871255 intact:EBI-358189|ensembl:ENSP00000323443|ensembl:ENSP00000345425|ensembl:ENSP00000353604 psi-mi:p04591-pro_0000038594(display_long)|uniprotkb:gag(gene name)|psi-mi:gag(display_short)|uniprotkb:Pr55Gag(gene name synonym) psi-mi:o95793-2(display_long)|uniprotkb:STAU1(gene name)|psi-mi:STAU1(display_short)|uniprotkb:STAU(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ghoujal et al. (2012) pubmed:22978549|imex:IM-24875 taxid:11706(hv1h2)|taxid:11706("Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-10690684|imex:IM-24875-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6163428(chain-parent) intact:EBI-358174(stau_human)|ensembl:ENSG00000124214(gene)|ensembl:ENST00000340954(transcript)|ensembl:ENST00000347458(transcript)|ensembl:ENST00000360426(transcript)|uniprotkb:O95793-2(isoform-parent) - chain-seq-start:133|chain-seq-end:363 - figure legend:1B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2015/03/06 2015/12/17 rogid:NJ62KblcsbHWlDc+IpZFGufRPjU11706 rogid:+JW/UIpMSSJSWv/4RT/yCLYjaUo9606 rigid:v9+Rdfx7U7sPD8YNe/Y3GVLmDA0 false - ha tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O95793-2 uniprotkb:Q96H20 intact:EBI-358189|ensembl:ENSP00000323443|ensembl:ENSP00000345425|ensembl:ENSP00000353604 intact:EBI-747719|uniprotkb:Q8IXY3|uniprotkb:Q9UN50|ensembl:ENSP00000421380 psi-mi:o95793-2(display_long)|uniprotkb:STAU1(gene name)|psi-mi:STAU1(display_short)|uniprotkb:STAU(gene name synonym) psi-mi:snf8_human(display_long)|uniprotkb:ELL-associated protein of 30 kDa(gene name synonym)|uniprotkb:SNF8(gene name)|psi-mi:SNF8(display_short)|uniprotkb:EAP30(gene name synonym)|uniprotkb:ESCRT-II complex subunit VPS22(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ghoujal et al. (2012) pubmed:22978549|imex:IM-24875 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-11472118|imex:IM-24875-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-358174(stau_human)|ensembl:ENSG00000124214(gene)|ensembl:ENST00000340954(transcript)|ensembl:ENST00000347458(transcript)|ensembl:ENST00000360426(transcript)|uniprotkb:O95793-2(isoform-parent) refseq:NP_009172.2|refseq:NP_001304121.1|refseq:NP_001304122.1|refseq:NP_001304123.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016247"(channel regulator activity)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903772"(regulation of viral budding via host ESCRT complex)|interpro:IPR016689(ESCRT-2 complex, Snf8)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040608|mint:Q96H20|rcsb pdb:2ZME|rcsb pdb:3CUQ|reactome:R-HSA-917729|reactome:R-HSA-9610379|ensembl:ENSG00000159210(gene)|ensembl:ENST00000502492(transcript)|go:"GO:0000814"(ESCRT II complex) - - - figure legend:1B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2015/03/06 2016/01/05 rogid:+JW/UIpMSSJSWv/4RT/yCLYjaUo9606 rogid:FyjlBpOt9okBFV8Z+g8YLUeyCm49606 rigid:ibYJGNpCdbFTHsc0Dhcxa3mWBFI false ha tag:c-c flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q96H20 uniprotkb:P04591-PRO_0000038594 intact:EBI-747719|uniprotkb:Q8IXY3|uniprotkb:Q9UN50|ensembl:ENSP00000421380 intact:EBI-9871255 psi-mi:snf8_human(display_long)|uniprotkb:ELL-associated protein of 30 kDa(gene name synonym)|uniprotkb:SNF8(gene name)|psi-mi:SNF8(display_short)|uniprotkb:EAP30(gene name synonym)|uniprotkb:ESCRT-II complex subunit VPS22(gene name synonym) psi-mi:p04591-pro_0000038594(display_long)|uniprotkb:gag(gene name)|psi-mi:gag(display_short)|uniprotkb:Pr55Gag(gene name synonym) psi-mi:"MI:0090"(protein complementation assay) Ghoujal et al. (2012) pubmed:22978549|imex:IM-24875 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:11706(hv1h2)|taxid:11706("Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-11472145|imex:IM-24875-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009172.2|refseq:NP_001304121.1|refseq:NP_001304122.1|refseq:NP_001304123.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016247"(channel regulator activity)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903772"(regulation of viral budding via host ESCRT complex)|interpro:IPR016689(ESCRT-2 complex, Snf8)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040608|mint:Q96H20|rcsb pdb:2ZME|rcsb pdb:3CUQ|reactome:R-HSA-917729|reactome:R-HSA-9610379|ensembl:ENSG00000159210(gene)|ensembl:ENST00000502492(transcript)|go:"GO:0000814"(ESCRT II complex) intact:EBI-6163428(chain-parent) go:"GO:0031410"(cytoplasmic vesicle) - chain-seq-start:133|chain-seq-end:363 figure legend:2B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2015/03/06 2015/12/17 rogid:FyjlBpOt9okBFV8Z+g8YLUeyCm49606 rogid:NJ62KblcsbHWlDc+IpZFGufRPjU11706 rigid:BxtaCA6Hi+PXgO8cUXDBkUO7rfw false fusion protein:?-? venus c-terminal fragment:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:O95793-2 uniprotkb:Q96H20 intact:EBI-358189|ensembl:ENSP00000323443|ensembl:ENSP00000345425|ensembl:ENSP00000353604 intact:EBI-747719|uniprotkb:Q8IXY3|uniprotkb:Q9UN50|ensembl:ENSP00000421380 psi-mi:o95793-2(display_long)|uniprotkb:STAU1(gene name)|psi-mi:STAU1(display_short)|uniprotkb:STAU(gene name synonym) psi-mi:snf8_human(display_long)|uniprotkb:ELL-associated protein of 30 kDa(gene name synonym)|uniprotkb:SNF8(gene name)|psi-mi:SNF8(display_short)|uniprotkb:EAP30(gene name synonym)|uniprotkb:ESCRT-II complex subunit VPS22(gene name synonym) psi-mi:"MI:0090"(protein complementation assay) Ghoujal et al. (2012) pubmed:22978549|imex:IM-24875 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-11472160|imex:IM-24875-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-358174(stau_human)|ensembl:ENSG00000124214(gene)|ensembl:ENST00000340954(transcript)|ensembl:ENST00000347458(transcript)|ensembl:ENST00000360426(transcript)|uniprotkb:O95793-2(isoform-parent) refseq:NP_009172.2|refseq:NP_001304121.1|refseq:NP_001304122.1|refseq:NP_001304123.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016247"(channel regulator activity)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903772"(regulation of viral budding via host ESCRT complex)|interpro:IPR016689(ESCRT-2 complex, Snf8)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040608|mint:Q96H20|rcsb pdb:2ZME|rcsb pdb:3CUQ|reactome:R-HSA-917729|reactome:R-HSA-9610379|ensembl:ENSG00000159210(gene)|ensembl:ENST00000502492(transcript)|go:"GO:0000814"(ESCRT II complex) go:"GO:0048471"(perinuclear region of cytoplasm) - - figure legend:2c|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2015/03/06 2015/12/17 rogid:+JW/UIpMSSJSWv/4RT/yCLYjaUo9606 rogid:FyjlBpOt9okBFV8Z+g8YLUeyCm49606 rigid:ibYJGNpCdbFTHsc0Dhcxa3mWBFI false venus c-terminal fragment:?-? fusion protein:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence)