#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q96BT7 uniprotkb:P40227 intact:EBI-10825637|uniprotkb:B1Q2M0|uniprotkb:B4DEF6|uniprotkb:Q8N989|ensembl:ENSP00000374219|ensembl:ENSP00000415885 intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2 psi-mi:alkb8_human(display_long)|uniprotkb:Probable alpha-ketoglutarate-dependent dioxygenase ABH8(gene name synonym)|uniprotkb:S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8(gene name synonym)|uniprotkb:"tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8"(gene name synonym)|uniprotkb:ABH8(gene name synonym)|uniprotkb:ALKBH8(gene name)|psi-mi:ALKBH8(display_short) psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fu et al. (2010) imex:IM-24230|pubmed:20308323 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10825748|imex:IM-24230-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001287939.1|refseq:NP_620130.2|ensembl:ENSG00000137760(gene)|ensembl:ENST00000389568(transcript)|ensembl:ENST00000428149(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016300"("tRNA (uracil) methyltransferase activity")|go:"GO:0016604"(nuclear body)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030488"(tRNA methylation)|go:"GO:0106335"("tRNA (carboxymethyluridine(34)-5-O)-methyltransferase activity")|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR015095(Region of unknown function DUF1891)|interpro:IPR027450|interpro:IPR029063|interpro:IPR034256|interpro:IPR035979|rcsb pdb:2CQ2|rcsb pdb:3THP|rcsb pdb:3THT|reactome:R-HSA-6782315 refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/05/29 2015/06/08 rogid:45RDrj2pdEfqaYo8Cuel6Vjh9j49606 rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606 rigid:nCqfbheXrDXzF5+dhBubM4vjlzQ false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96BT7 uniprotkb:P17987 intact:EBI-10825637|uniprotkb:B1Q2M0|uniprotkb:B4DEF6|uniprotkb:Q8N989|ensembl:ENSP00000374219|ensembl:ENSP00000415885 intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334 psi-mi:alkb8_human(display_long)|uniprotkb:Probable alpha-ketoglutarate-dependent dioxygenase ABH8(gene name synonym)|uniprotkb:S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8(gene name synonym)|uniprotkb:"tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8"(gene name synonym)|uniprotkb:ABH8(gene name synonym)|uniprotkb:ALKBH8(gene name)|psi-mi:ALKBH8(display_short) psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fu et al. (2010) imex:IM-24230|pubmed:20308323 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10825748|imex:IM-24230-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001287939.1|refseq:NP_620130.2|ensembl:ENSG00000137760(gene)|ensembl:ENST00000389568(transcript)|ensembl:ENST00000428149(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016300"("tRNA (uracil) methyltransferase activity")|go:"GO:0016604"(nuclear body)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030488"(tRNA methylation)|go:"GO:0106335"("tRNA (carboxymethyluridine(34)-5-O)-methyltransferase activity")|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR015095(Region of unknown function DUF1891)|interpro:IPR027450|interpro:IPR029063|interpro:IPR034256|interpro:IPR035979|rcsb pdb:2CQ2|rcsb pdb:3THP|rcsb pdb:3THT|reactome:R-HSA-6782315 refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/05/29 2015/06/08 rogid:45RDrj2pdEfqaYo8Cuel6Vjh9j49606 rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606 rigid:nCqfbheXrDXzF5+dhBubM4vjlzQ false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96BT7 uniprotkb:P50990 intact:EBI-10825637|uniprotkb:B1Q2M0|uniprotkb:B4DEF6|uniprotkb:Q8N989|ensembl:ENSP00000374219|ensembl:ENSP00000415885 intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788 psi-mi:alkb8_human(display_long)|uniprotkb:Probable alpha-ketoglutarate-dependent dioxygenase ABH8(gene name synonym)|uniprotkb:S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8(gene name synonym)|uniprotkb:"tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8"(gene name synonym)|uniprotkb:ABH8(gene name synonym)|uniprotkb:ALKBH8(gene name)|psi-mi:ALKBH8(display_short) psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fu et al. (2010) imex:IM-24230|pubmed:20308323 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10825748|imex:IM-24230-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001287939.1|refseq:NP_620130.2|ensembl:ENSG00000137760(gene)|ensembl:ENST00000389568(transcript)|ensembl:ENST00000428149(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016300"("tRNA (uracil) methyltransferase activity")|go:"GO:0016604"(nuclear body)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030488"(tRNA methylation)|go:"GO:0106335"("tRNA (carboxymethyluridine(34)-5-O)-methyltransferase activity")|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR015095(Region of unknown function DUF1891)|interpro:IPR027450|interpro:IPR029063|interpro:IPR034256|interpro:IPR035979|rcsb pdb:2CQ2|rcsb pdb:3THP|rcsb pdb:3THT|reactome:R-HSA-6782315 refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/05/29 2015/06/08 rogid:45RDrj2pdEfqaYo8Cuel6Vjh9j49606 rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606 rigid:nCqfbheXrDXzF5+dhBubM4vjlzQ false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96BT7 uniprotkb:P07900 intact:EBI-10825637|uniprotkb:B1Q2M0|uniprotkb:B4DEF6|uniprotkb:Q8N989|ensembl:ENSP00000374219|ensembl:ENSP00000415885 intact:EBI-296047|intact:EBI-1642144|uniprotkb:Q2PP14|ensembl:ENSP00000216281|uniprotkb:Q5CAQ6|uniprotkb:Q5CAQ7|uniprotkb:Q9BVQ5|intact:EBI-2211817|uniprotkb:A8K500|uniprotkb:B3KPJ9 psi-mi:alkb8_human(display_long)|uniprotkb:Probable alpha-ketoglutarate-dependent dioxygenase ABH8(gene name synonym)|uniprotkb:S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8(gene name synonym)|uniprotkb:"tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8"(gene name synonym)|uniprotkb:ABH8(gene name synonym)|uniprotkb:ALKBH8(gene name)|psi-mi:ALKBH8(display_short) psi-mi:hs90a_human(display_long)|uniprotkb:HSP90AA1(gene name)|psi-mi:HSP90AA1(display_short)|uniprotkb:HSP90A(gene name synonym)|uniprotkb:HSPC1(gene name synonym)|uniprotkb:Heat shock 86 kDa(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-38(gene name synonym)|uniprotkb:HSPCA(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fu et al. (2010) imex:IM-24230|pubmed:20308323 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10825748|imex:IM-24230-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001287939.1|refseq:NP_620130.2|ensembl:ENSG00000137760(gene)|ensembl:ENST00000389568(transcript)|ensembl:ENST00000428149(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016300"("tRNA (uracil) methyltransferase activity")|go:"GO:0016604"(nuclear body)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030488"(tRNA methylation)|go:"GO:0106335"("tRNA (carboxymethyluridine(34)-5-O)-methyltransferase activity")|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR015095(Region of unknown function DUF1891)|interpro:IPR027450|interpro:IPR029063|interpro:IPR034256|interpro:IPR035979|rcsb pdb:2CQ2|rcsb pdb:3THP|rcsb pdb:3THT|reactome:R-HSA-6782315 go:"GO:0009409"(response to cold)|go:"GO:0016020"(membrane)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032273"(positive regulation of protein polymerization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903827"|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P07900|rcsb pdb:1BYQ|rcsb pdb:1OSF|rcsb pdb:1UY6|rcsb pdb:1UY7|ensembl:ENST00000216281(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000080824(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009408"(response to heat)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043209"(myelin sheath)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043335"(protein unfolding)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051020"(GTPase binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1UY9|rcsb pdb:1UYC|rcsb pdb:1UYD|rcsb pdb:1UYE|rcsb pdb:1UYF|rcsb pdb:1UYG|rcsb pdb:1UYH|rcsb pdb:1UYI|rcsb pdb:1UYK|rcsb pdb:1UYL|rcsb pdb:1UY8|rcsb pdb:1YC1|rcsb pdb:1YC3|rcsb pdb:1YC4|rcsb pdb:1YER|rcsb pdb:1YES|rcsb pdb:1YET|rcsb pdb:2BSM|rcsb pdb:2BT0|rcsb pdb:2BUG|rcsb pdb:2WI1|rcsb pdb:2WI2|rcsb pdb:2WI3|rcsb pdb:2WI4|rcsb pdb:2WI5|rcsb pdb:2WI6|rcsb pdb:2WI7|rcsb pdb:2XAB|rcsb pdb:2XDK|rcsb pdb:2XDL|rcsb pdb:2XDS|rcsb pdb:2XDU|rcsb pdb:2XDX|rcsb pdb:2XHR|rcsb pdb:2XHT|rcsb pdb:2XHX|rcsb pdb:2XJG|rcsb pdb:2XJJ|rcsb pdb:2XJX|rcsb pdb:2XK2|rcsb pdb:2YE2|rcsb pdb:2YE3|rcsb pdb:2YE4|rcsb pdb:2YE5|rcsb pdb:2YE6|rcsb pdb:2YE7|rcsb pdb:2YE8|rcsb pdb:2YE9|rcsb pdb:2YEA|rcsb pdb:2YEB|rcsb pdb:2BYI|rcsb pdb:2BZ5|rcsb pdb:2C2L|rcsb pdb:2CCS|rcsb pdb:2CCT|rcsb pdb:2CCU|rcsb pdb:2FWY|rcsb pdb:2FWZ|rcsb pdb:2H55|rcsb pdb:2JJC|rcsb pdb:2K5B|rcsb pdb:2QF6|rcsb pdb:2QFO|rcsb pdb:2QG0|rcsb pdb:2QG2|rcsb pdb:2UWD|rcsb pdb:2VCI|rcsb pdb:2BYH|rcsb pdb:2VCJ|rcsb pdb:3B25|rcsb pdb:3B26|rcsb pdb:3B27|rcsb pdb:3B28|rcsb pdb:3BM9|rcsb pdb:3BMY|rcsb pdb:3D0B|rcsb pdb:3EKO|rcsb pdb:3EKR|rcsb pdb:3FT5|rcsb pdb:3FT8|rcsb pdb:3HEK|rcsb pdb:3HHU|rcsb pdb:3HYY|rcsb pdb:3HYZ|rcsb pdb:3HZ1|rcsb pdb:3HZ5|rcsb pdb:3INW|rcsb pdb:3B24|rcsb pdb:3INX|rcsb pdb:3K97|rcsb pdb:3K98|rcsb pdb:2YEC|rcsb pdb:2YED|rcsb pdb:2YEE|rcsb pdb:2YEF|rcsb pdb:2YEG|rcsb pdb:2YEH|rcsb pdb:2YEI|rcsb pdb:2YEJ|rcsb pdb:2YI0|rcsb pdb:2YI5|rcsb pdb:2YI6|rcsb pdb:2YI7|rcsb pdb:2YJW|rcsb pdb:2YJX|rcsb pdb:2YK2|rcsb pdb:2YK9|rcsb pdb:2YKB|rcsb pdb:2YKC|rcsb pdb:2YKE|rcsb pdb:2YKI|rcsb pdb:2YKJ|rcsb pdb:4CWF|rcsb pdb:4CWN|rcsb pdb:4CWO|rcsb pdb:4CWP|rcsb pdb:4CWQ|rcsb pdb:4CWR|rcsb pdb:4CWS|rcsb pdb:4CWT|rcsb pdb:4EEH|rcsb pdb:4EFT|rcsb pdb:4EFU|rcsb pdb:4EGH|rcsb pdb:4EGI|rcsb pdb:4EGK|rcsb pdb:4FCP|rcsb pdb:4FCQ|rcsb pdb:4FCR|rcsb pdb:4HY6|rcsb pdb:4JQL|rcsb pdb:4L8Z|rcsb pdb:4L90|rcsb pdb:4L91|rcsb pdb:5LO5|rcsb pdb:5LO6|rcsb pdb:5LQ9|rcsb pdb:5LR1|rcsb pdb:5LR7|rcsb pdb:5LRL|rcsb pdb:5LRZ|rcsb pdb:5LS1|rcsb pdb:5M4E|rcsb pdb:5M4H|rcsb pdb:5NYH|rcsb pdb:5NYI|rcsb pdb:5OCI|rcsb pdb:5OD7|rcsb pdb:5ODX|rcsb pdb:5T21|rcsb pdb:5VYY|rcsb pdb:5XQD|rcsb pdb:5XQE|rcsb pdb:5XR5|rcsb pdb:5XR9|rcsb pdb:5XRB|rcsb pdb:5XRD|rcsb pdb:5XRE|rcsb pdb:5LO1|rcsb pdb:5ZR3|rcsb pdb:6B99|rcsb pdb:6B9A|rcsb pdb:6CEO|rcsb pdb:6CYG|rcsb pdb:6EI5|rcsb pdb:6EL5|rcsb pdb:6ELN|rcsb pdb:6ELO|rcsb pdb:6ELP|rcsb pdb:6EY8|rcsb pdb:6EY9|rcsb pdb:6EYA|rcsb pdb:6EYB|rcsb pdb:6F1N|rcsb pdb:6FCJ|rcsb pdb:6FDP|rcsb pdb:6GP4|rcsb pdb:6GP8|rcsb pdb:6GPF|rcsb pdb:6GPH|rcsb pdb:6CYH|rcsb pdb:6GPO|rcsb pdb:6GPP|rcsb pdb:6GPR|rcsb pdb:6GPT|rcsb pdb:6GPW|rcsb pdb:6GPY|rcsb pdb:6GQ6|rcsb pdb:6GQR|rcsb pdb:6GQS|rcsb pdb:6GQU|rcsb pdb:6GR1|rcsb pdb:6GR3|rcsb pdb:6GR4|rcsb pdb:6GR5|rcsb pdb:6HHR|rcsb pdb:6KSQ|rcsb pdb:6LR9|rcsb pdb:6LSZ|rcsb pdb:6LT8|rcsb pdb:6LTI|rcsb pdb:6LTK|rcsb pdb:6N8X|rcsb pdb:6OLX|rcsb pdb:6TN5|rcsb pdb:6U98|rcsb pdb:6U99|rcsb pdb:6U9A|rcsb pdb:6U9B|rcsb pdb:7LSZ|rcsb pdb:7LT0|reactome:R-HSA-1227986|reactome:R-HSA-1236382|rcsb pdb:6TN4|reactome:R-HSA-1474151|reactome:R-HSA-168928|reactome:R-HSA-192905|reactome:R-HSA-2029482|reactome:R-HSA-203615|reactome:R-HSA-2565942|reactome:R-HSA-3000484|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-399954|reactome:R-HSA-4420097|reactome:R-HSA-5218920|reactome:R-HSA-5336415|reactome:R-HSA-5601884|reactome:R-HSA-5620912|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8863795|reactome:R-HSA-8939211|reactome:R-HSA-9009391|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9634285|reactome:R-HSA-9646399|reactome:R-HSA-9652282|reactome:R-HSA-9665233|reactome:R-HSA-9664565|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|reactome:R-HSA-9679191|rcsb pdb:3MNR|rcsb pdb:3O0I|rcsb pdb:3OW6|rcsb pdb:3OWB|rcsb pdb:3OWD|rcsb pdb:3Q6M|rcsb pdb:3Q6N|rcsb pdb:3QDD|rcsb pdb:3QTF|rcsb pdb:3R4M|rcsb pdb:3R4N|rcsb pdb:3R4O|rcsb pdb:3R4P|rcsb pdb:3R91|rcsb pdb:3R92|rcsb pdb:3K99|rcsb pdb:3RKZ|rcsb pdb:3RLP|rcsb pdb:3RLQ|rcsb pdb:3RLR|rcsb pdb:4L93|rcsb pdb:4L94|rcsb pdb:4LWE|rcsb pdb:4LWF|rcsb pdb:4LWG|rcsb pdb:4LWH|rcsb pdb:4LWI|rcsb pdb:4NH7|rcsb pdb:4NH8|rcsb pdb:4O04|rcsb pdb:4O05|rcsb pdb:4O07|rcsb pdb:4O09|rcsb pdb:4O0B|rcsb pdb:4R3M|rcsb pdb:4U93|rcsb pdb:4W7T|rcsb pdb:4XIP|rcsb pdb:4XIQ|rcsb pdb:4XIR|rcsb pdb:4XIT|rcsb pdb:4YKQ|rcsb pdb:4YKR|rcsb pdb:4YKT|rcsb pdb:4YKU|rcsb pdb:4YKW|rcsb pdb:4YKX|rcsb pdb:4YKY|rcsb pdb:3T0Z|rcsb pdb:3T10|rcsb pdb:3T1K|rcsb pdb:3T2S|rcsb pdb:3TUH|rcsb pdb:3VHA|rcsb pdb:3VHC|rcsb pdb:3VHD|rcsb pdb:3WHA|rcsb pdb:3WQ9|rcsb pdb:4AIF|rcsb pdb:4AWO|rcsb pdb:4AWP|rcsb pdb:3T0H|rcsb pdb:4AWQ|rcsb pdb:4B7P|rcsb pdb:4BQG|rcsb pdb:4BQJ|rcsb pdb:4CGQ|rcsb pdb:4CGU|rcsb pdb:4CGV|rcsb pdb:4CGW|rcsb pdb:5CF0|rcsb pdb:5FNC|rcsb pdb:5FND|rcsb pdb:5FNF|rcsb pdb:5GGZ|rcsb pdb:5J20|rcsb pdb:5J27|rcsb pdb:5J2V|rcsb pdb:5J2X|rcsb pdb:5J64|rcsb pdb:5J6L|rcsb pdb:5J6M|rcsb pdb:5J6N|rcsb pdb:5J80|rcsb pdb:5J82|rcsb pdb:5J86|rcsb pdb:5J8M|rcsb pdb:5J8U|rcsb pdb:5J9X|rcsb pdb:4YKZ|rcsb pdb:5LNY|rcsb pdb:5LNZ|rcsb pdb:5LO0|refseq:NP_001017963.2|refseq:NP_005339.3|dip:DIP-27595N - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/05/29 2015/06/08 rogid:45RDrj2pdEfqaYo8Cuel6Vjh9j49606 rogid:qfaAHww82iR1p0hvrJY5oavsNyA9606 rigid:nCqfbheXrDXzF5+dhBubM4vjlzQ false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96BT7 uniprotkb:P50991 intact:EBI-10825637|uniprotkb:B1Q2M0|uniprotkb:B4DEF6|uniprotkb:Q8N989|ensembl:ENSP00000374219|ensembl:ENSP00000415885 intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958 psi-mi:alkb8_human(display_long)|uniprotkb:Probable alpha-ketoglutarate-dependent dioxygenase ABH8(gene name synonym)|uniprotkb:S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8(gene name synonym)|uniprotkb:"tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8"(gene name synonym)|uniprotkb:ABH8(gene name synonym)|uniprotkb:ALKBH8(gene name)|psi-mi:ALKBH8(display_short) psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fu et al. (2010) imex:IM-24230|pubmed:20308323 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10825748|imex:IM-24230-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001287939.1|refseq:NP_620130.2|ensembl:ENSG00000137760(gene)|ensembl:ENST00000389568(transcript)|ensembl:ENST00000428149(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016300"("tRNA (uracil) methyltransferase activity")|go:"GO:0016604"(nuclear body)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030488"(tRNA methylation)|go:"GO:0106335"("tRNA (carboxymethyluridine(34)-5-O)-methyltransferase activity")|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR015095(Region of unknown function DUF1891)|interpro:IPR027450|interpro:IPR029063|interpro:IPR034256|interpro:IPR035979|rcsb pdb:2CQ2|rcsb pdb:3THP|rcsb pdb:3THT|reactome:R-HSA-6782315 refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/05/29 2015/06/08 rogid:45RDrj2pdEfqaYo8Cuel6Vjh9j49606 rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606 rigid:nCqfbheXrDXzF5+dhBubM4vjlzQ false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96BT7 uniprotkb:P78371 intact:EBI-10825637|uniprotkb:B1Q2M0|uniprotkb:B4DEF6|uniprotkb:Q8N989|ensembl:ENSP00000374219|ensembl:ENSP00000415885 intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300 psi-mi:alkb8_human(display_long)|uniprotkb:Probable alpha-ketoglutarate-dependent dioxygenase ABH8(gene name synonym)|uniprotkb:S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8(gene name synonym)|uniprotkb:"tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8"(gene name synonym)|uniprotkb:ABH8(gene name synonym)|uniprotkb:ALKBH8(gene name)|psi-mi:ALKBH8(display_short) psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fu et al. (2010) imex:IM-24230|pubmed:20308323 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10825748|imex:IM-24230-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001287939.1|refseq:NP_620130.2|ensembl:ENSG00000137760(gene)|ensembl:ENST00000389568(transcript)|ensembl:ENST00000428149(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016300"("tRNA (uracil) methyltransferase activity")|go:"GO:0016604"(nuclear body)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030488"(tRNA methylation)|go:"GO:0106335"("tRNA (carboxymethyluridine(34)-5-O)-methyltransferase activity")|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR015095(Region of unknown function DUF1891)|interpro:IPR027450|interpro:IPR029063|interpro:IPR034256|interpro:IPR035979|rcsb pdb:2CQ2|rcsb pdb:3THP|rcsb pdb:3THT|reactome:R-HSA-6782315 refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/05/29 2015/06/08 rogid:45RDrj2pdEfqaYo8Cuel6Vjh9j49606 rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606 rigid:nCqfbheXrDXzF5+dhBubM4vjlzQ false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96BT7 uniprotkb:P48643 intact:EBI-10825637|uniprotkb:B1Q2M0|uniprotkb:B4DEF6|uniprotkb:Q8N989|ensembl:ENSP00000374219|ensembl:ENSP00000415885 intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8 psi-mi:alkb8_human(display_long)|uniprotkb:Probable alpha-ketoglutarate-dependent dioxygenase ABH8(gene name synonym)|uniprotkb:S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8(gene name synonym)|uniprotkb:"tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8"(gene name synonym)|uniprotkb:ABH8(gene name synonym)|uniprotkb:ALKBH8(gene name)|psi-mi:ALKBH8(display_short) psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fu et al. (2010) imex:IM-24230|pubmed:20308323 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10825748|imex:IM-24230-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001287939.1|refseq:NP_620130.2|ensembl:ENSG00000137760(gene)|ensembl:ENST00000389568(transcript)|ensembl:ENST00000428149(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016300"("tRNA (uracil) methyltransferase activity")|go:"GO:0016604"(nuclear body)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030488"(tRNA methylation)|go:"GO:0106335"("tRNA (carboxymethyluridine(34)-5-O)-methyltransferase activity")|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR015095(Region of unknown function DUF1891)|interpro:IPR027450|interpro:IPR029063|interpro:IPR034256|interpro:IPR035979|rcsb pdb:2CQ2|rcsb pdb:3THP|rcsb pdb:3THT|reactome:R-HSA-6782315 refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/05/29 2015/06/08 rogid:45RDrj2pdEfqaYo8Cuel6Vjh9j49606 rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606 rigid:nCqfbheXrDXzF5+dhBubM4vjlzQ false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96BT7 uniprotkb:Q99832 intact:EBI-10825637|uniprotkb:B1Q2M0|uniprotkb:B4DEF6|uniprotkb:Q8N989|ensembl:ENSP00000374219|ensembl:ENSP00000415885 intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091 psi-mi:alkb8_human(display_long)|uniprotkb:Probable alpha-ketoglutarate-dependent dioxygenase ABH8(gene name synonym)|uniprotkb:S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8(gene name synonym)|uniprotkb:"tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8"(gene name synonym)|uniprotkb:ABH8(gene name synonym)|uniprotkb:ALKBH8(gene name)|psi-mi:ALKBH8(display_short) psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fu et al. (2010) imex:IM-24230|pubmed:20308323 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10825748|imex:IM-24230-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001287939.1|refseq:NP_620130.2|ensembl:ENSG00000137760(gene)|ensembl:ENST00000389568(transcript)|ensembl:ENST00000428149(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016300"("tRNA (uracil) methyltransferase activity")|go:"GO:0016604"(nuclear body)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030488"(tRNA methylation)|go:"GO:0106335"("tRNA (carboxymethyluridine(34)-5-O)-methyltransferase activity")|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR015095(Region of unknown function DUF1891)|interpro:IPR027450|interpro:IPR029063|interpro:IPR034256|interpro:IPR035979|rcsb pdb:2CQ2|rcsb pdb:3THP|rcsb pdb:3THT|reactome:R-HSA-6782315 dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/05/29 2015/06/08 rogid:45RDrj2pdEfqaYo8Cuel6Vjh9j49606 rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606 rigid:nCqfbheXrDXzF5+dhBubM4vjlzQ false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96BT7 uniprotkb:Q9UI30 intact:EBI-10825637|uniprotkb:B1Q2M0|uniprotkb:B4DEF6|uniprotkb:Q8N989|ensembl:ENSP00000374219|ensembl:ENSP00000415885 intact:EBI-373326|uniprotkb:Q3MHC7|uniprotkb:Q8N2Z4|uniprotkb:B2R539|uniprotkb:J3KNG5|ensembl:ENSP00000438349 psi-mi:alkb8_human(display_long)|uniprotkb:Probable alpha-ketoglutarate-dependent dioxygenase ABH8(gene name synonym)|uniprotkb:S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8(gene name synonym)|uniprotkb:"tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8"(gene name synonym)|uniprotkb:ABH8(gene name synonym)|uniprotkb:ALKBH8(gene name)|psi-mi:ALKBH8(display_short) psi-mi:tr112_human(display_long)|uniprotkb:tRNA methyltransferase 112 homolog(gene name synonym)|uniprotkb:AD-001(orf name)|uniprotkb:HSPC152(orf name)|uniprotkb:HSPC170(orf name)|uniprotkb:TRMT112(gene name)|psi-mi:TRMT112(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fu et al. (2010) imex:IM-24230|pubmed:20308323 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10825748|imex:IM-24230-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001287939.1|refseq:NP_620130.2|ensembl:ENSG00000137760(gene)|ensembl:ENST00000389568(transcript)|ensembl:ENST00000428149(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016300"("tRNA (uracil) methyltransferase activity")|go:"GO:0016604"(nuclear body)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030488"(tRNA methylation)|go:"GO:0106335"("tRNA (carboxymethyluridine(34)-5-O)-methyltransferase activity")|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR015095(Region of unknown function DUF1891)|interpro:IPR027450|interpro:IPR029063|interpro:IPR034256|interpro:IPR035979|rcsb pdb:2CQ2|rcsb pdb:3THP|rcsb pdb:3THT|reactome:R-HSA-6782315 refseq:NP_001273011.1|refseq:NP_057488.1|ensembl:ENSG00000173113(gene)|ensembl:ENST00000544844(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0018364"(peptidyl-glutamine methylation)|go:"GO:0030488"(tRNA methylation)|go:"GO:0031167"(rRNA methylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070476"("rRNA (guanine-N7)-methylation")|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR005651(Protein of unknown function DUF343)|mint:Q9UI30|rcsb pdb:6G4W|rcsb pdb:6H1D|rcsb pdb:6H1E|rcsb pdb:6H2U|rcsb pdb:6H2V|rcsb pdb:6K0X|rcsb pdb:6KHS|rcsb pdb:6KMR|rcsb pdb:6KMS|rcsb pdb:6PED|reactome:R-HSA-156581|reactome:R-HSA-6782315|reactome:R-HSA-6790901|reactome:R-HSA-72764|interpro:IPR039127 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/05/29 2015/06/08 rogid:45RDrj2pdEfqaYo8Cuel6Vjh9j49606 rogid:N3kvBRpRMFAeB5AYgOmAvs34u+c9606 rigid:nCqfbheXrDXzF5+dhBubM4vjlzQ false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96BT7 uniprotkb:Q59H77 intact:EBI-10825637|uniprotkb:B1Q2M0|uniprotkb:B4DEF6|uniprotkb:Q8N989|ensembl:ENSP00000374219|ensembl:ENSP00000415885 intact:EBI-10825733 psi-mi:alkb8_human(display_long)|uniprotkb:Probable alpha-ketoglutarate-dependent dioxygenase ABH8(gene name synonym)|uniprotkb:S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8(gene name synonym)|uniprotkb:"tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8"(gene name synonym)|uniprotkb:ABH8(gene name synonym)|uniprotkb:ALKBH8(gene name)|psi-mi:ALKBH8(display_short) psi-mi:q59h77_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fu et al. (2010) imex:IM-24230|pubmed:20308323 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10825748|imex:IM-24230-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001287939.1|refseq:NP_620130.2|ensembl:ENSG00000137760(gene)|ensembl:ENST00000389568(transcript)|ensembl:ENST00000428149(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016300"("tRNA (uracil) methyltransferase activity")|go:"GO:0016604"(nuclear body)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030488"(tRNA methylation)|go:"GO:0106335"("tRNA (carboxymethyluridine(34)-5-O)-methyltransferase activity")|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR015095(Region of unknown function DUF1891)|interpro:IPR027450|interpro:IPR029063|interpro:IPR034256|interpro:IPR035979|rcsb pdb:2CQ2|rcsb pdb:3THP|rcsb pdb:3THT|reactome:R-HSA-6782315 refseq:NP_005989.3|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR027409|interpro:IPR027413|interpro:IPR027410|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/05/29 2015/06/08 rogid:45RDrj2pdEfqaYo8Cuel6Vjh9j49606 rogid:tn8HSeQgYEs249MFFURgFAPpceg9606 rigid:nCqfbheXrDXzF5+dhBubM4vjlzQ false flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96BT7 uniprotkb:P17987 intact:EBI-10825637|uniprotkb:B1Q2M0|uniprotkb:B4DEF6|uniprotkb:Q8N989|ensembl:ENSP00000374219|ensembl:ENSP00000415885 intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334 psi-mi:alkb8_human(display_long)|uniprotkb:Probable alpha-ketoglutarate-dependent dioxygenase ABH8(gene name synonym)|uniprotkb:S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8(gene name synonym)|uniprotkb:"tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8"(gene name synonym)|uniprotkb:ABH8(gene name synonym)|uniprotkb:ALKBH8(gene name)|psi-mi:ALKBH8(display_short) psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fu et al. (2010) imex:IM-24230|pubmed:20308323 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10825868|imex:IM-24230-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001287939.1|refseq:NP_620130.2|ensembl:ENSG00000137760(gene)|ensembl:ENST00000389568(transcript)|ensembl:ENST00000428149(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016300"("tRNA (uracil) methyltransferase activity")|go:"GO:0016604"(nuclear body)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030488"(tRNA methylation)|go:"GO:0106335"("tRNA (carboxymethyluridine(34)-5-O)-methyltransferase activity")|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR015095(Region of unknown function DUF1891)|interpro:IPR027450|interpro:IPR029063|interpro:IPR034256|interpro:IPR035979|rcsb pdb:2CQ2|rcsb pdb:3THP|rcsb pdb:3THT|reactome:R-HSA-6782315 refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N - - - figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/05/29 2015/06/17 rogid:45RDrj2pdEfqaYo8Cuel6Vjh9j49606 rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606 rigid:m4ZUnzj48Y2gte6Hk/Wc0CAt+iU false flag tag:n-n|sufficient binding region:411..411-664 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96BT7 uniprotkb:P50990 intact:EBI-10825637|uniprotkb:B1Q2M0|uniprotkb:B4DEF6|uniprotkb:Q8N989|ensembl:ENSP00000374219|ensembl:ENSP00000415885 intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788 psi-mi:alkb8_human(display_long)|uniprotkb:Probable alpha-ketoglutarate-dependent dioxygenase ABH8(gene name synonym)|uniprotkb:S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8(gene name synonym)|uniprotkb:"tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8"(gene name synonym)|uniprotkb:ABH8(gene name synonym)|uniprotkb:ALKBH8(gene name)|psi-mi:ALKBH8(display_short) psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fu et al. (2010) imex:IM-24230|pubmed:20308323 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10825868|imex:IM-24230-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001287939.1|refseq:NP_620130.2|ensembl:ENSG00000137760(gene)|ensembl:ENST00000389568(transcript)|ensembl:ENST00000428149(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016300"("tRNA (uracil) methyltransferase activity")|go:"GO:0016604"(nuclear body)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030488"(tRNA methylation)|go:"GO:0106335"("tRNA (carboxymethyluridine(34)-5-O)-methyltransferase activity")|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR015095(Region of unknown function DUF1891)|interpro:IPR027450|interpro:IPR029063|interpro:IPR034256|interpro:IPR035979|rcsb pdb:2CQ2|rcsb pdb:3THP|rcsb pdb:3THT|reactome:R-HSA-6782315 refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N - - - figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/05/29 2015/06/17 rogid:45RDrj2pdEfqaYo8Cuel6Vjh9j49606 rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606 rigid:m4ZUnzj48Y2gte6Hk/Wc0CAt+iU false flag tag:n-n|sufficient binding region:411..411-664 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96BT7 uniprotkb:P78371 intact:EBI-10825637|uniprotkb:B1Q2M0|uniprotkb:B4DEF6|uniprotkb:Q8N989|ensembl:ENSP00000374219|ensembl:ENSP00000415885 intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300 psi-mi:alkb8_human(display_long)|uniprotkb:Probable alpha-ketoglutarate-dependent dioxygenase ABH8(gene name synonym)|uniprotkb:S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8(gene name synonym)|uniprotkb:"tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8"(gene name synonym)|uniprotkb:ABH8(gene name synonym)|uniprotkb:ALKBH8(gene name)|psi-mi:ALKBH8(display_short) psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fu et al. (2010) imex:IM-24230|pubmed:20308323 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10825868|imex:IM-24230-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001287939.1|refseq:NP_620130.2|ensembl:ENSG00000137760(gene)|ensembl:ENST00000389568(transcript)|ensembl:ENST00000428149(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016300"("tRNA (uracil) methyltransferase activity")|go:"GO:0016604"(nuclear body)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030488"(tRNA methylation)|go:"GO:0106335"("tRNA (carboxymethyluridine(34)-5-O)-methyltransferase activity")|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR015095(Region of unknown function DUF1891)|interpro:IPR027450|interpro:IPR029063|interpro:IPR034256|interpro:IPR035979|rcsb pdb:2CQ2|rcsb pdb:3THP|rcsb pdb:3THT|reactome:R-HSA-6782315 refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695 - - - figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/05/29 2015/06/17 rogid:45RDrj2pdEfqaYo8Cuel6Vjh9j49606 rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606 rigid:m4ZUnzj48Y2gte6Hk/Wc0CAt+iU false flag tag:n-n|sufficient binding region:411..411-664 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96BT7 uniprotkb:P17987 intact:EBI-10825637|uniprotkb:B1Q2M0|uniprotkb:B4DEF6|uniprotkb:Q8N989|ensembl:ENSP00000374219|ensembl:ENSP00000415885 intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334 psi-mi:alkb8_human(display_long)|uniprotkb:Probable alpha-ketoglutarate-dependent dioxygenase ABH8(gene name synonym)|uniprotkb:S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8(gene name synonym)|uniprotkb:"tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8"(gene name synonym)|uniprotkb:ABH8(gene name synonym)|uniprotkb:ALKBH8(gene name)|psi-mi:ALKBH8(display_short) psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fu et al. (2010) imex:IM-24230|pubmed:20308323 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10890041|imex:IM-24230-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001287939.1|refseq:NP_620130.2|ensembl:ENSG00000137760(gene)|ensembl:ENST00000389568(transcript)|ensembl:ENST00000428149(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016300"("tRNA (uracil) methyltransferase activity")|go:"GO:0016604"(nuclear body)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030488"(tRNA methylation)|go:"GO:0106335"("tRNA (carboxymethyluridine(34)-5-O)-methyltransferase activity")|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR015095(Region of unknown function DUF1891)|interpro:IPR027450|interpro:IPR029063|interpro:IPR034256|interpro:IPR035979|rcsb pdb:2CQ2|rcsb pdb:3THP|rcsb pdb:3THT|reactome:R-HSA-6782315 refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N - - - figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/05/29 2015/06/17 rogid:45RDrj2pdEfqaYo8Cuel6Vjh9j49606 rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606 rigid:DonOXKfk9FhvoeSEnBE376N5hgk false flag tag:n-n|sufficient binding region:126-664 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96BT7 uniprotkb:P50990 intact:EBI-10825637|uniprotkb:B1Q2M0|uniprotkb:B4DEF6|uniprotkb:Q8N989|ensembl:ENSP00000374219|ensembl:ENSP00000415885 intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788 psi-mi:alkb8_human(display_long)|uniprotkb:Probable alpha-ketoglutarate-dependent dioxygenase ABH8(gene name synonym)|uniprotkb:S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8(gene name synonym)|uniprotkb:"tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8"(gene name synonym)|uniprotkb:ABH8(gene name synonym)|uniprotkb:ALKBH8(gene name)|psi-mi:ALKBH8(display_short) psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fu et al. (2010) imex:IM-24230|pubmed:20308323 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10890041|imex:IM-24230-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001287939.1|refseq:NP_620130.2|ensembl:ENSG00000137760(gene)|ensembl:ENST00000389568(transcript)|ensembl:ENST00000428149(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016300"("tRNA (uracil) methyltransferase activity")|go:"GO:0016604"(nuclear body)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030488"(tRNA methylation)|go:"GO:0106335"("tRNA (carboxymethyluridine(34)-5-O)-methyltransferase activity")|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR015095(Region of unknown function DUF1891)|interpro:IPR027450|interpro:IPR029063|interpro:IPR034256|interpro:IPR035979|rcsb pdb:2CQ2|rcsb pdb:3THP|rcsb pdb:3THT|reactome:R-HSA-6782315 refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N - - - figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/05/29 2015/06/17 rogid:45RDrj2pdEfqaYo8Cuel6Vjh9j49606 rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606 rigid:DonOXKfk9FhvoeSEnBE376N5hgk false flag tag:n-n|sufficient binding region:126-664 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96BT7 uniprotkb:P78371 intact:EBI-10825637|uniprotkb:B1Q2M0|uniprotkb:B4DEF6|uniprotkb:Q8N989|ensembl:ENSP00000374219|ensembl:ENSP00000415885 intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300 psi-mi:alkb8_human(display_long)|uniprotkb:Probable alpha-ketoglutarate-dependent dioxygenase ABH8(gene name synonym)|uniprotkb:S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8(gene name synonym)|uniprotkb:"tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8"(gene name synonym)|uniprotkb:ABH8(gene name synonym)|uniprotkb:ALKBH8(gene name)|psi-mi:ALKBH8(display_short) psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fu et al. (2010) imex:IM-24230|pubmed:20308323 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10890041|imex:IM-24230-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001287939.1|refseq:NP_620130.2|ensembl:ENSG00000137760(gene)|ensembl:ENST00000389568(transcript)|ensembl:ENST00000428149(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016300"("tRNA (uracil) methyltransferase activity")|go:"GO:0016604"(nuclear body)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030488"(tRNA methylation)|go:"GO:0106335"("tRNA (carboxymethyluridine(34)-5-O)-methyltransferase activity")|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR015095(Region of unknown function DUF1891)|interpro:IPR027450|interpro:IPR029063|interpro:IPR034256|interpro:IPR035979|rcsb pdb:2CQ2|rcsb pdb:3THP|rcsb pdb:3THT|reactome:R-HSA-6782315 refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695 - - - figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/05/29 2015/06/17 rogid:45RDrj2pdEfqaYo8Cuel6Vjh9j49606 rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606 rigid:DonOXKfk9FhvoeSEnBE376N5hgk false flag tag:n-n|sufficient binding region:126-664 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96BT7 uniprotkb:Q9UI30 intact:EBI-10825637|uniprotkb:B1Q2M0|uniprotkb:B4DEF6|uniprotkb:Q8N989|ensembl:ENSP00000374219|ensembl:ENSP00000415885 intact:EBI-373326|uniprotkb:Q3MHC7|uniprotkb:Q8N2Z4|uniprotkb:B2R539|uniprotkb:J3KNG5|ensembl:ENSP00000438349 psi-mi:alkb8_human(display_long)|uniprotkb:Probable alpha-ketoglutarate-dependent dioxygenase ABH8(gene name synonym)|uniprotkb:S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8(gene name synonym)|uniprotkb:"tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8"(gene name synonym)|uniprotkb:ABH8(gene name synonym)|uniprotkb:ALKBH8(gene name)|psi-mi:ALKBH8(display_short) psi-mi:tr112_human(display_long)|uniprotkb:tRNA methyltransferase 112 homolog(gene name synonym)|uniprotkb:AD-001(orf name)|uniprotkb:HSPC152(orf name)|uniprotkb:HSPC170(orf name)|uniprotkb:TRMT112(gene name)|psi-mi:TRMT112(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fu et al. (2010) imex:IM-24230|pubmed:20308323 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10890041|imex:IM-24230-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001287939.1|refseq:NP_620130.2|ensembl:ENSG00000137760(gene)|ensembl:ENST00000389568(transcript)|ensembl:ENST00000428149(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016300"("tRNA (uracil) methyltransferase activity")|go:"GO:0016604"(nuclear body)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030488"(tRNA methylation)|go:"GO:0106335"("tRNA (carboxymethyluridine(34)-5-O)-methyltransferase activity")|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR015095(Region of unknown function DUF1891)|interpro:IPR027450|interpro:IPR029063|interpro:IPR034256|interpro:IPR035979|rcsb pdb:2CQ2|rcsb pdb:3THP|rcsb pdb:3THT|reactome:R-HSA-6782315 refseq:NP_001273011.1|refseq:NP_057488.1|ensembl:ENSG00000173113(gene)|ensembl:ENST00000544844(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0018364"(peptidyl-glutamine methylation)|go:"GO:0030488"(tRNA methylation)|go:"GO:0031167"(rRNA methylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070476"("rRNA (guanine-N7)-methylation")|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR005651(Protein of unknown function DUF343)|mint:Q9UI30|rcsb pdb:6G4W|rcsb pdb:6H1D|rcsb pdb:6H1E|rcsb pdb:6H2U|rcsb pdb:6H2V|rcsb pdb:6K0X|rcsb pdb:6KHS|rcsb pdb:6KMR|rcsb pdb:6KMS|rcsb pdb:6PED|reactome:R-HSA-156581|reactome:R-HSA-6782315|reactome:R-HSA-6790901|reactome:R-HSA-72764|interpro:IPR039127 - - - figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2015/05/29 2015/06/17 rogid:45RDrj2pdEfqaYo8Cuel6Vjh9j49606 rogid:N3kvBRpRMFAeB5AYgOmAvs34u+c9606 rigid:DonOXKfk9FhvoeSEnBE376N5hgk false flag tag:n-n|sufficient binding region:126-664 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UI30 uniprotkb:Q96BT7 intact:EBI-373326|uniprotkb:Q3MHC7|uniprotkb:Q8N2Z4|uniprotkb:B2R539|uniprotkb:J3KNG5|ensembl:ENSP00000438349 intact:EBI-10825637|uniprotkb:B1Q2M0|uniprotkb:B4DEF6|uniprotkb:Q8N989|ensembl:ENSP00000374219|ensembl:ENSP00000415885 psi-mi:tr112_human(display_long)|uniprotkb:tRNA methyltransferase 112 homolog(gene name synonym)|uniprotkb:AD-001(orf name)|uniprotkb:HSPC152(orf name)|uniprotkb:HSPC170(orf name)|uniprotkb:TRMT112(gene name)|psi-mi:TRMT112(display_short) psi-mi:alkb8_human(display_long)|uniprotkb:Probable alpha-ketoglutarate-dependent dioxygenase ABH8(gene name synonym)|uniprotkb:S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8(gene name synonym)|uniprotkb:"tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8"(gene name synonym)|uniprotkb:ABH8(gene name synonym)|uniprotkb:ALKBH8(gene name)|psi-mi:ALKBH8(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fu et al. (2010) imex:IM-24230|pubmed:20308323 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-10825850|imex:IM-24230-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001273011.1|refseq:NP_057488.1|ensembl:ENSG00000173113(gene)|ensembl:ENST00000544844(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0018364"(peptidyl-glutamine methylation)|go:"GO:0030488"(tRNA methylation)|go:"GO:0031167"(rRNA methylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070476"("rRNA (guanine-N7)-methylation")|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR005651(Protein of unknown function DUF343)|mint:Q9UI30|rcsb pdb:6G4W|rcsb pdb:6H1D|rcsb pdb:6H1E|rcsb pdb:6H2U|rcsb pdb:6H2V|rcsb pdb:6K0X|rcsb pdb:6KHS|rcsb pdb:6KMR|rcsb pdb:6KMS|rcsb pdb:6PED|reactome:R-HSA-156581|reactome:R-HSA-6782315|reactome:R-HSA-6790901|reactome:R-HSA-72764|interpro:IPR039127 refseq:NP_001287939.1|refseq:NP_620130.2|ensembl:ENSG00000137760(gene)|ensembl:ENST00000389568(transcript)|ensembl:ENST00000428149(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016300"("tRNA (uracil) methyltransferase activity")|go:"GO:0016604"(nuclear body)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030488"(tRNA methylation)|go:"GO:0106335"("tRNA (carboxymethyluridine(34)-5-O)-methyltransferase activity")|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR015095(Region of unknown function DUF1891)|interpro:IPR027450|interpro:IPR029063|interpro:IPR034256|interpro:IPR035979|rcsb pdb:2CQ2|rcsb pdb:3THP|rcsb pdb:3THT|reactome:R-HSA-6782315 - - - figure legend:Fig. 2D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2015/05/29 2015/06/08 rogid:N3kvBRpRMFAeB5AYgOmAvs34u+c9606 rogid:45RDrj2pdEfqaYo8Cuel6Vjh9j49606 rigid:zRe+PTVMzK+sguzpqtCQmBb5gZ0 false - flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)