#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P58301	uniprotkb:P58301	intact:EBI-2505704|ensemblbacteria:AAL81291	intact:EBI-2505704|ensemblbacteria:AAL81291	psi-mi:rad50_pyrfu(display_long)|uniprotkb:rad50(gene name)|psi-mi:rad50(display_short)|uniprotkb:pfRad50(gene name synonym)|uniprotkb:PF1167(locus name)	psi-mi:rad50_pyrfu(display_long)|uniprotkb:rad50(gene name)|psi-mi:rad50(display_short)|uniprotkb:pfRad50(gene name synonym)|uniprotkb:PF1167(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Deshpande et al. (2014)	pubmed:24493214|imex:IM-23096	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9348981|imex:IM-23096-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAL81291(transcript)|ensemblbacteria:PF1167(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016787"(hydrolase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR022982|interpro:IPR027417|interpro:IPR038729|rcsb pdb:1F2T|rcsb pdb:1F2U|rcsb pdb:1II8|rcsb pdb:1L8D|rcsb pdb:1US8|rcsb pdb:3QKR|rcsb pdb:3QKS|rcsb pdb:3QKT|rcsb pdb:3QKU|rcsb pdb:4NCH|rcsb pdb:4NCI|rcsb pdb:4NCJ|rcsb pdb:4NCK|rcsb pdb:6ZFF|interpro:IPR013134(Zinc hook, Rad50)|refseq:WP_011012307.1|dip:DIP-54373N	ensemblbacteria:AAL81291(transcript)|ensemblbacteria:PF1167(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016787"(hydrolase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR022982|interpro:IPR027417|interpro:IPR038729|rcsb pdb:1F2T|rcsb pdb:1F2U|rcsb pdb:1II8|rcsb pdb:1L8D|rcsb pdb:1US8|rcsb pdb:3QKR|rcsb pdb:3QKS|rcsb pdb:3QKT|rcsb pdb:3QKU|rcsb pdb:4NCH|rcsb pdb:4NCI|rcsb pdb:4NCJ|rcsb pdb:4NCK|rcsb pdb:6ZFF|interpro:IPR013134(Zinc hook, Rad50)|refseq:WP_011012307.1|dip:DIP-54373N	rcsb pdb:IM-23096-1(imex-primary)|rcsb pdb:4NCH|rcsb pdb:4NCK|rcsb pdb:4NCI|rcsb pdb:4NCJ	-	-	figure legend:t1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/04/02	2014/10/16	rogid:vvNFVksbWSbwW6N3e98xeKa+HBY186497	rogid:vvNFVksbWSbwW6N3e98xeKa+HBY186497	intact-crc:D3A90908560BF591|rigid:toq0DY9xR+MmGGRxLrLFYFXEb4Q	false	-	-	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P58301	uniprotkb:P58301	intact:EBI-2505704|ensemblbacteria:AAL81291	intact:EBI-2505704|ensemblbacteria:AAL81291	psi-mi:rad50_pyrfu(display_long)|uniprotkb:rad50(gene name)|psi-mi:rad50(display_short)|uniprotkb:pfRad50(gene name synonym)|uniprotkb:PF1167(locus name)	psi-mi:rad50_pyrfu(display_long)|uniprotkb:rad50(gene name)|psi-mi:rad50(display_short)|uniprotkb:pfRad50(gene name synonym)|uniprotkb:PF1167(locus name)	psi-mi:"MI:0071"(molecular sieving)	Deshpande et al. (2014)	pubmed:24493214|imex:IM-23096	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9819287|imex:IM-23096-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAL81291(transcript)|ensemblbacteria:PF1167(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016787"(hydrolase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR022982|interpro:IPR027417|interpro:IPR038729|rcsb pdb:1F2T|rcsb pdb:1F2U|rcsb pdb:1II8|rcsb pdb:1L8D|rcsb pdb:1US8|rcsb pdb:3QKR|rcsb pdb:3QKS|rcsb pdb:3QKT|rcsb pdb:3QKU|rcsb pdb:4NCH|rcsb pdb:4NCI|rcsb pdb:4NCJ|rcsb pdb:4NCK|rcsb pdb:6ZFF|interpro:IPR013134(Zinc hook, Rad50)|refseq:WP_011012307.1|dip:DIP-54373N	ensemblbacteria:AAL81291(transcript)|ensemblbacteria:PF1167(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016787"(hydrolase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR022982|interpro:IPR027417|interpro:IPR038729|rcsb pdb:1F2T|rcsb pdb:1F2U|rcsb pdb:1II8|rcsb pdb:1L8D|rcsb pdb:1US8|rcsb pdb:3QKR|rcsb pdb:3QKS|rcsb pdb:3QKT|rcsb pdb:3QKU|rcsb pdb:4NCH|rcsb pdb:4NCI|rcsb pdb:4NCJ|rcsb pdb:4NCK|rcsb pdb:6ZFF|interpro:IPR013134(Zinc hook, Rad50)|refseq:WP_011012307.1|dip:DIP-54373N	rcsb pdb:4NCH|rcsb pdb:4NCK|rcsb pdb:4NCI	-	-	figure legend:sf1b f2a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/04/02	2014/10/16	rogid:vvNFVksbWSbwW6N3e98xeKa+HBY186497	rogid:vvNFVksbWSbwW6N3e98xeKa+HBY186497	intact-crc:42360B62A09E4497|rigid:toq0DY9xR+MmGGRxLrLFYFXEb4Q	false	binding-associated region:1-882|mutation disrupting interaction:802-802	binding-associated region:1-882|mutation disrupting interaction:802-802	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P58301	uniprotkb:P58301	intact:EBI-2505704|ensemblbacteria:AAL81291	intact:EBI-2505704|ensemblbacteria:AAL81291	psi-mi:rad50_pyrfu(display_long)|uniprotkb:rad50(gene name)|psi-mi:rad50(display_short)|uniprotkb:pfRad50(gene name synonym)|uniprotkb:PF1167(locus name)	psi-mi:rad50_pyrfu(display_long)|uniprotkb:rad50(gene name)|psi-mi:rad50(display_short)|uniprotkb:pfRad50(gene name synonym)|uniprotkb:PF1167(locus name)	psi-mi:"MI:0030"(cross-linking study)	Deshpande et al. (2014)	pubmed:24493214|imex:IM-23096	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9819396|imex:IM-23096-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAL81291(transcript)|ensemblbacteria:PF1167(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016787"(hydrolase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR022982|interpro:IPR027417|interpro:IPR038729|rcsb pdb:1F2T|rcsb pdb:1F2U|rcsb pdb:1II8|rcsb pdb:1L8D|rcsb pdb:1US8|rcsb pdb:3QKR|rcsb pdb:3QKS|rcsb pdb:3QKT|rcsb pdb:3QKU|rcsb pdb:4NCH|rcsb pdb:4NCI|rcsb pdb:4NCJ|rcsb pdb:4NCK|rcsb pdb:6ZFF|interpro:IPR013134(Zinc hook, Rad50)|refseq:WP_011012307.1|dip:DIP-54373N	ensemblbacteria:AAL81291(transcript)|ensemblbacteria:PF1167(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016787"(hydrolase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR022982|interpro:IPR027417|interpro:IPR038729|rcsb pdb:1F2T|rcsb pdb:1F2U|rcsb pdb:1II8|rcsb pdb:1L8D|rcsb pdb:1US8|rcsb pdb:3QKR|rcsb pdb:3QKS|rcsb pdb:3QKT|rcsb pdb:3QKU|rcsb pdb:4NCH|rcsb pdb:4NCI|rcsb pdb:4NCJ|rcsb pdb:4NCK|rcsb pdb:6ZFF|interpro:IPR013134(Zinc hook, Rad50)|refseq:WP_011012307.1|dip:DIP-54373N	rcsb pdb:4NCH|rcsb pdb:4NCK|rcsb pdb:4NCI	-	-	figure legend:F7B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/04/02	2014/10/16	rogid:vvNFVksbWSbwW6N3e98xeKa+HBY186497	rogid:vvNFVksbWSbwW6N3e98xeKa+HBY186497	intact-crc:D872E7F7138E23EC|rigid:toq0DY9xR+MmGGRxLrLFYFXEb4Q	false	-	-	2	0	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:P58301	uniprotkb:Q8U1N9	intact:EBI-2505704|ensemblbacteria:AAL81291	intact:EBI-2014945|ensemblbacteria:AAL81290	psi-mi:rad50_pyrfu(display_long)|uniprotkb:rad50(gene name)|psi-mi:rad50(display_short)|uniprotkb:pfRad50(gene name synonym)|uniprotkb:PF1167(locus name)	psi-mi:mre11_pyrfu(display_long)|uniprotkb:mre11(gene name)|psi-mi:mre11(display_short)|uniprotkb:pfMre11(gene name synonym)|uniprotkb:PF1166(locus name)	psi-mi:"MI:0030"(cross-linking study)	Deshpande et al. (2014)	pubmed:24493214|imex:IM-23096	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9819428|imex:IM-23096-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAL81291(transcript)|ensemblbacteria:PF1167(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016787"(hydrolase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR022982|interpro:IPR027417|interpro:IPR038729|rcsb pdb:1F2T|rcsb pdb:1F2U|rcsb pdb:1II8|rcsb pdb:1L8D|rcsb pdb:1US8|rcsb pdb:3QKR|rcsb pdb:3QKS|rcsb pdb:3QKT|rcsb pdb:3QKU|rcsb pdb:4NCH|rcsb pdb:4NCI|rcsb pdb:4NCJ|rcsb pdb:4NCK|rcsb pdb:6ZFF|interpro:IPR013134(Zinc hook, Rad50)|refseq:WP_011012307.1|dip:DIP-54373N	dip:DIP-52386N|ensemblbacteria:AAL81290(transcript)|ensemblbacteria:PF1166(gene)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045027"(DNA end binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR029052|interpro:IPR032885|interpro:IPR041796|rcsb pdb:1II7|rcsb pdb:1S8E|rcsb pdb:3DSC|rcsb pdb:3DSD|rcsb pdb:3QKR|rcsb pdb:3QKS|rcsb pdb:3QKU|rcsb pdb:4HD0	rcsb pdb:4NCH|rcsb pdb:4NCK|rcsb pdb:4NCI	-	-	figure legend:F7C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/04/02	2014/10/16	rogid:vvNFVksbWSbwW6N3e98xeKa+HBY186497	rogid:Mgf8L+4uDXb3qMP0/Mbju9KE7AM186497	intact-crc:9067CE2C2EEDC55D|rigid:Ga6l0qHFZtKWwPAr545YRHIYO3E	false	-	-	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q8U1N9	uniprotkb:P58301	intact:EBI-2014945|ensemblbacteria:AAL81290	intact:EBI-2505704|ensemblbacteria:AAL81291	psi-mi:mre11_pyrfu(display_long)|uniprotkb:mre11(gene name)|psi-mi:mre11(display_short)|uniprotkb:pfMre11(gene name synonym)|uniprotkb:PF1166(locus name)	psi-mi:rad50_pyrfu(display_long)|uniprotkb:rad50(gene name)|psi-mi:rad50(display_short)|uniprotkb:pfRad50(gene name synonym)|uniprotkb:PF1167(locus name)	psi-mi:"MI:0826"(x ray scattering)	Deshpande et al. (2014)	pubmed:24493214|imex:IM-23096	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9993843|imex:IM-23096-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-52386N|ensemblbacteria:AAL81290(transcript)|ensemblbacteria:PF1166(gene)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045027"(DNA end binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR029052|interpro:IPR032885|interpro:IPR041796|rcsb pdb:1II7|rcsb pdb:1S8E|rcsb pdb:3DSC|rcsb pdb:3DSD|rcsb pdb:3QKR|rcsb pdb:3QKS|rcsb pdb:3QKU|rcsb pdb:4HD0	ensemblbacteria:AAL81291(transcript)|ensemblbacteria:PF1167(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016787"(hydrolase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR022982|interpro:IPR027417|interpro:IPR038729|rcsb pdb:1F2T|rcsb pdb:1F2U|rcsb pdb:1II8|rcsb pdb:1L8D|rcsb pdb:1US8|rcsb pdb:3QKR|rcsb pdb:3QKS|rcsb pdb:3QKT|rcsb pdb:3QKU|rcsb pdb:4NCH|rcsb pdb:4NCI|rcsb pdb:4NCJ|rcsb pdb:4NCK|rcsb pdb:6ZFF|interpro:IPR013134(Zinc hook, Rad50)|refseq:WP_011012307.1|dip:DIP-54373N	-	-	-	figure legend:sf2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/04/02	2014/12/02	rogid:Mgf8L+4uDXb3qMP0/Mbju9KE7AM186497	rogid:vvNFVksbWSbwW6N3e98xeKa+HBY186497	intact-crc:DCC87728935FFD07|rigid:Ga6l0qHFZtKWwPAr545YRHIYO3E	false	-	-	-	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)